検索結果 12683 件
| JaLCDOI | 10.18926/40247 |
|---|---|
| タイトル（別表記） | Studies on the Influences of Balneal Treatment on Female Sexual Function |
| フルテキストURL | pitsr_025_025_052.pdf |
| 著者 | 長谷川 安正| |
| 抄録 | In the present study, observations of changes on female sexual function by balneal treatment were carried out with female rats with respects to sexual cycle, histological changes in ovary and uterus, histo-chemical changes in pituitary, cholinesterase activity in brain, cholesterol levels in ovary, etc. The results obtained were as follows. 1) Significant changes of sexual cycle appeared in 47 (62%) out of the 76 rats which were treated with several kinds of artificial balneal water at the temperature of 42°C (for 5 minutes per single course of the balneal treatment, twice daily during 4 weeks). Similar changes of sexual cycle also appeared in the subjects which were treated with the same kinds of balneal water at 37°C, though having showed to be less than the changes in case of the balneal treatment at 42°C. 2) A significant tendency of regulating sexual cycle of rat to normal was demonstrated in the subjects which were treated with artificial balneal sulfer, and on the other hand, a significant tendency of disturbing the cycle was demonstrated in the sUbjects which were treated with artificial balneal acid and alkali. 3) A tendency of extending the period of dioesterus phase in sexual cycle of rat was found in the subjects which were treated with our laboratory' balneal water at 42°C for 10 minutes per single course four times daily during 10 days. In these subjects, it was also demonstrated that the period of the estrus phase tended to be prolonged. 4) Histological pictures in ovary and uterus indicated normal growth in the subjects of which the sexual cycles were normalized by balneal treatment, whereas indicated an atrophy in the subjects of which the cycles were disturbed. Significant atrophy tended to appear remarkably in the subjects which developed some irregular cycles due to the treatment with artificial balneal acid or alkali. In view point of the daily changes in these tissues, it was demonstrated that atrophic changes appeared at the 10th day after onset of the treatment with a balneal water at 42°C for 5 minutes per single course or with a balneal water at 37°C for 5 minutes, and then turned to normal pictures at the 20th day after onset of the treatment. It was also indicated that remarkable atrophic changes in ovary and uterus appeared immediately after 10 days treatment with a balneal water at 42°C for 10 minutes per single course four times daily, and then turned to show a slight hyperfunction in the ovary at the 10th day after discontinuation of this balneal treatment. 5) A certain correlation was found between cholinesterase activity in the brain of rat and counts of PAS positive cells in the anterior pituitary (on the sexual zone named by Purves, H. D and W. E. Griesbach). Both the activity and the counts decreased at the 10th day after onset of the balneal treatment at the temperature of 42°C for 5 minutes per single course twice daily, and then increased at the 20th day after onset of this treatment. It was also demonstrated that both the activity and the counts decreased significantly at the 10th day after onset of the balneal treatment at 42°C for 10 minutes per single course four times daily, and then increased remarkably at the 10th day after discontinuation of this treatment. 6) A negative correlation was demonstrated between changes of cholesterol levels in ovary and those of cholinesterase activity in brain. Both the levels and the activity increased transitorily at the 10th day after the balneal treatment at 42°C for 5 minutes per single course, and then decreased at the 20th day after onset of the treatment. It was also demonstrated that both the activity and the levels increased at the 10th day after onset of the treatment at 42°C for 10 minutes per single course four times daily, and then decreased after discontinuation of this treatment. From the results mentioned above the following deduction may be drawn: (a) Sexual function is affected apparently by balneal treatment; (b) As to the mode of action of balneal water on sexual function, it is likely that balneal water acts extensively on autonomic nervous system, followed by producing changes in sexual function. In the other words, it seems that balneal water primarily affects on upper central nervous system, i. e. diencephalo-hypophyseo-system, and secondarily produces changes in sexual gland; (c) It was also demonstrated that though a transitory depression in sexual function appeared individually in some subjects which were treated with extensive stimulative balneal water or over time of balneal treatment, but in even the same subjects hyperfunction often appeared after discontinuation of such a treatment. These evidence should be taken into consideration in case of clinical balneotherapy; (d) In view point that the balneotherapy produces changes in sexual function through acting on central nervous system, it may be suggested that balneotherapy with conventional hormon therapy could produce the most desirous effect for the treatment of fertility and insufficiency of sexual function. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-05 |
| 巻 | 25巻 |
| 開始ページ | 25 |
| 終了ページ | 52 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462888 |
| JaLCDOI | 10.18926/40246 |
|---|---|
| タイトル（別表記） | Studies on the Chemical Composition and Levels of Ground Water at Misasa Hot Springs |
| フルテキストURL | 025_013_024.pdf |
| 著者 | 坂上 正信| |
| 抄録 | The water levels of the thermal springs and the ground water levels were measured and the contour of the water table was obtained. The contour was disturbed at two regions in which many springs issue. The thermal and ground waters were sampled all over the springs district, and the water temperatures were measured when they were sampled. The chloride, bicarbonate, sulfate, calcium and magnesium content was also determined. In addition, the analytical methods for the determination of arsenic, phosphorus and acid-soluble iron were improved. Also the concentration of these elements was determined. Based on the results of the observations and chemical analysis, the relations between the water temperatures and content of chemical constituent and the chloride content were checked respectively. Positive correlations were found in the relations between water temperature～Cl(-), HCO(3)(-)～Cl(-), SO(4)(2-)～Cl(-), Ca(2+)～Cl(-), and As～Cl(-). Furthermore, the regional differences were detectable in the ratios of water temperature to chloride content and of bicarbonate to chloride content, nevertheless the correlation as a whole were valid. The diversity and regional differences of the chemical composition of the waters were explained as due to the differences in the mixing proportion of the magmatic thermal water and the varying kinds of ground water at the deep site in the ground and at the site near the ground surfaces. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-05 |
| 巻 | 25巻 |
| 開始ページ | 13 |
| 終了ページ | 24 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40244 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/40242 |
|---|---|
| タイトル（別表記） | Clinical Studies on Anemia in Rheumatoid Arthritis (III) |
| フルテキストURL | 026_050_063.pdf |
| 著者 | 山本 泰久| |
| 抄録 | III. The Effects of Balneotherapy and Antianemics on Anemia in Rheumatoid Arthritis 1. Balneotherapy: The author investigated the changes of the peripheral blood picture, erythrocyte sedimentation rate, numbers of finger-ring (Wheatsheaf's ring-test) and grasping power (by means of hand-dynamometer or sphygmometer) before and after baneotherapy. The regimen of spa treatment in our hospital includes bathing in radioactive hot spring (42-3°C. in temperature)two or three times a day, local mud bath or mud pack (once or twice a day, massage and drinking of spring water. These measures performed for one or two months. When the spa treatment has finished the erythrocyte count and Hb-content of rheumatoid patients increased in 61% of 33 cases examined comparing with before treatment, leucocyte count tended to shift to normal and E.S.R. decreased in 58% of the cases. The swelling of the finger joints diminished. 2. Oral iron therapy: In previous report, the author verified that there exist simple iron deficiency anemia in some cases of rheumatoid arthritis. Oral iron therapy responded well in such cases, but the majority of cases were resistant to oral iron. 3. Transfusion of blood in rheumatoid anemia: The author transfused 100 ml. of blood once a day for 5-10 days in 11 rheumatoid anemic patients. By the treatment of transfusion, the findings in peripheral blood improved and E.S.R. decreased. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-10 |
| 巻 | 26巻 |
| 開始ページ | 50 |
| 終了ページ | 63 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/40241 |
|---|---|
| タイトル（別表記） | Clinical Studies on Anemia in Rheumatoid Arthritis (II) |
| フルテキストURL | 026_031_049.pdf |
| 著者 | 山本 泰久| |
| 抄録 | II. Iron Metabolism 1. The serum iron: The serum iron was estimated by the method of Umemoto and Yamamoto (by means of o-nitroso resorcinmonomethylether) The average serum iron level of 33 cases with rheumatoid arthritis was 47γ/100 ml., and in 27 of 33 cases (82%) the serum iron levels were shown to be below the lower limit of the normal range (5% rejection limit: 54-141γ/100 ml. ), but the concentrations of serum iron of neuralgias (degenerative Spondylosis, sciatica and painful shoulder) were mostly within the normal range. 2. Iron absorption: To investigate the possible role of poor absorption in preventing a response to oral iron therapy, the changes in serum iron were followed after a test of iron by mouth in 16 caseS with rheumatoid arthritis. The test dose was 1 gm. of reduced iron given with 30 mI. of lemonade-pepsin solution to preserve the iron in the ferrous state and obviate the effects of possible achlorhydria in rheumatoid patients. The results may be grouped under three headings: a) Large rise in serum iron: good adsorption. Three caseS (19%) showed a very large rise in serum iron after the test dose, which is similar to simple iron-deficiency anemia. b) Slight rise in serum iron: presumed poor absorption. Six cases (38%) showed a very small or negligible rise after the test dose, so that at its peak the serum iron was below the normal range. c) In the remaining 7 cases, a maximal rise in serum iron after the test dose was within the normal range. 3. The iron-binding capacity of the serum: The iron-binding capacity of the serum was estimated by means of intravenous injection of Gluferricon (Fe content: 10 mg.). The mean total iron-binding capacity of the serum in the present 13 cases with rheumatoid arthritis was 273γ/100ml., virtually the same as the normal figure (287γ /100 ml.). The degree of saturation of the iron-binding protein with iron was found to lie between 18 and 45% (average: 34%) in control sUbjects and between 7 and 24% (average: 16%) in rheumatoid patients. 4. The serum copper: The serum copper was estimated by means of diethyldithiocarbamate in rheumatoid arthritis with the following results. Healthy subjects: men (15 cases): mean 89.9±14.8γ /l00 ml., women (15 cases): mean 99.9± 12.6γ/100 ml. There is no significant difference between the two. In 10 of 17 cases (57%) with rheumatoid arthritis, the serum copper levels were shown to be above the upper limit of the normal range (57-138γ/100 ml. ・・・5% rejection limit), neuralgias were mostly (92%) within the normal range. The results of investigations upon alternations in iron metabolism of rheumatoid anemia are reported. 1. The serum iron concentration was usually reduced. 2. The intestinal absorption of iron after a single dose of 1 gm. of reduced iron was variable. Strong presumptive evidence of impaired absorption waS recognised in many cases, but some cases gave the excellent absorption. From these results, it seems that simple iron deficiency exist in some anemic caseS of rheumatoid arthritis. 3. The total iron-binding capacity of the serum was slightly reduced. 4. The degree of Saturation of iron-binding protein with iron was below nornal. 5. The serum copper concentration waS usually elevated. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-10 |
| 巻 | 26巻 |
| 開始ページ | 31 |
| 終了ページ | 49 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/40240 |
|---|---|
| タイトル（別表記） | Clinical Study on the Treatment of Rheumatoid Arthritis Part III. Experiences of Capsulosynovectomia Genu Anterior Totalis for Rheumatoid Arthritis |
| フルテキストURL | 026_020_030.pdf |
| 著者 | 泉 友圀| |
| 抄録 | Capsulosynovectomia genu anterior totalis was performed on five cases had marked hydrops and capsular thickening of joints, in which intraarticular injection of hydrocortisone or prednisolone, balneotherapy and hydrotherapy had been repeated in vain for long period with long standing pain and gradual decrease in motor function. The progress was observed for six to seventeen months after the operation, obtaining following results. Rheumatic symptoms were significantly improved after operation and restortion of function was also valuable. No exacerbations in the other joints and general condition were noted with rather improvement in the sign. Further, these operated joints became to react better, differ from preoperative, to balneotherapy and "Fango" with noticeable effects on the restoration of articular function. In histological findings of the resected synovia four cases showed Rs. and one Fr. by T. Kodama's classification. It is, therefore, recommended to appreciate this kind of operation on the cases shown no effects in the treatment of adrenocortical hormone or hot spring bath, which led to the decrease in gait ability, on the standpoint of medical rehabilitation. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-10 |
| 巻 | 26巻 |
| 開始ページ | 20 |
| 終了ページ | 30 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/40239 |
|---|---|
| タイトル（別表記） | Clinical Study on the Treatment of Rheumatoid Arthritis Part II. Experiences of Intraarticular Injection of Prednisolone for Rheumatoid Arthritis |
| フルテキストURL | 026_008_019.pdf |
| 著者 | 泉 友圀| |
| 抄録 | Meticorterone (Prednisolone acetate) were injected into joints of 33 cases of rheumatoid arthritis, 172 times in total, with better results. Although intraarticular injection of prednisolone is, at present, to be one of the most effective treatment for rheumatoid arthritis, one must pay attention at the appearance of general effect in frequent and abundant injection. Comparative studies were performed on the effects of intraarticular injectons of prednisolone T. B. A, (on twelve cases), hydrocortisone acetate and meticorterone. Prednisolone T. B. A. was proved markedly longer effect in local with minimum general effect, It was, therefore, thought that prednisolone T. B. A. was safest and most effective in intraarticular therapy on the rheumatoid arthritis. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-10 |
| 巻 | 26巻 |
| 開始ページ | 8 |
| 終了ページ | 19 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/40238 |
|---|---|
| タイトル（別表記） | Clinical Study on the Treatment of Rheumatoid Arthritis Part I. Therapeutic Experiences by Hot Spring Bath and "Fango" using Clay of Nigyo-pass |
| フルテキストURL | pitsr_026_001_007.pdf |
| 著者 | 泉 友圀| |
| 抄録 | Rheumatoid arthritis, thought incurable for many years, was treated by radioactive hot spring bath and uranium deposit clay at Ningyo-pass. The therapeutic effects of balneotherapy and "Fango" were stUdied comparatively. Results of hot spring bath for one month were effective in 63 of 73 cases (86.3 per cent), and 60 per cent even in (222) chr., in which attaind Grade III. It was thought that therapeutic effect of bathing on (222) chr. was increased using together with adrenocortical hormone. Uranium deposit clay at Ningyo-pass was used on 59 cases of this disease, in form of "Fango" and local bath in mud. It was effective in 60.8 per cent of 171 joints, and in 53.4 per cent of 131 joints of (222) chr. It showed that this was valuable as a local therapy for those incurable types of the disease. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1959-10 |
| 巻 | 26巻 |
| 開始ページ | 1 |
| 終了ページ | 7 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462886 |
| JaLCDOI | 10.18926/40236 |
|---|---|
| タイトル（別表記） | Geochemical Studies on the Area of Hot Springs in Hamamura and Shikano District Comparison of Characteristics of Hot Springs in the Central part of Tottori Prefecture, Japan |
| フルテキストURL | 027_025_044.pdf |
| 著者 | 阪上 正信| 御船 政明| |
| 抄録 | The thermal and ground waters were sampled in the hot springs district of Hamamura-Katsumi and Shikano and in their neighborhoods. The water temperatures were measured when they were sampled. Among the major chemical constituents, the chloride, sulfate, bicarbonate (methyl-orange alkalinity), calcium and magnesium content was determined. Furthermore, as the minor constituents, the arsenic and phosphorus content was also determined. The uranium, radium and radon content was determined in some samples of hot springs. Based on the results of chemical analysis, the relations between the chloride content and the content of other chemical constituents were cheked respectively. Positive correlations were found in the relations between water temperature-Cl(-), SO(4)(2-)-Cl(-), Ca(2+)-Cl(-) and As-Cl(-), although the ratios of each content showed the different characteristic in Hamamura-Katsumi compared with that in Shikano. In the samples of Hamamura-Katsumi where the thermal waters were pumped out from the sedimentary beds of volcanic rocks, the sulfate and calcium content was relatively richer compared with the content of these ions in the samples of Shikano where granitic rocks underlay as the basement in the fairly shallow depth from the cground surface. These characteristics were also noticed when the chemical compositions of other hot springs in the central part of Tottori prefecture were examined. In the neighborhood of the hot springs district mentioned-above, distinctive indications of hot spring were found at Kinashi which was placed between Hamamura and Shikano, comprehensively examining the content of chemical constituents in the ground water samples in this region. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1961-01 |
| 巻 | 27巻 |
| 開始ページ | 25 |
| 終了ページ | 44 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532371 |
| JaLCDOI | 10.18926/40234 |
|---|---|
| フルテキストURL | pitsr_027_001_009.pdf |
| 著者 | Sakanoue, Masanobu| |
| 抄録 | In recent years, coulometric analysis has been developed and widely used as a technique for the determination of substances in solution by measuring the quantity of electricity required for the completion of a reaction in an electrolysis cell. Of two coulometric techniques, i. e., coulometric titration with a constant current and coulometric analysis with a controlled potential of a working electrode, the latter is more interesting to the author, because by this method both electrolytic separation and quantitative determination of chemical species can be achieved simultaneously. Especially, the use of a mercury cathode as the working electrode(1)) has an advantage that the optimum control potentials can easily be determinable from polarographic data. In our laboratory, we took up the coulometry of uranium as one of the interesting themes of researches when we had an opPortunity in studying various kinds of analytical methods for uranium in accordance with the request by Japan Atomic Fuel Corporation. The coulometric determination of uranium (VI) by using a mercury cathode at a controlled potential was studied by G. L. Booman, W. B. Holbrook and ]. E. Rein(2)). It was found to be very useful for the analysis of uranium in a highly enriched nuclear element which underwent fission to an appreciable extent. But the instrument used by them(3)) was complicated and expensive. Therefore, a simple counter millicoulometer has been coustructed in our laboratory, a readymade potentiostat (electrical instrument for automatic controlled potential electrolysis) being tried for electrolysis. By these instruments, the author studied the fundam ental conditions of coulometry for uranium and tried the successive determinations of uranium and thallium in mixed solutions. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1961-01 |
| 巻 | 27巻 |
| 開始ページ | 1 |
| 終了ページ | 9 |
| ISSN | 0369-7142 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002462884 |
| JaLCDOI | 10.18926/40223 |
|---|---|
| タイトル（別表記） | Chemcal Study on a Spring Well in Tottori Hot Springs |
| フルテキストURL | pitsr_029_050_056.pdf |
| 著者 | 阪上 正信| 杉原 健| |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1961-06-25 |
| 巻 | 29巻 |
| 開始ページ | 50 |
| 終了ページ | 56 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462883 |
| JaLCDOI | 10.18926/40222 |
|---|---|
| タイトル（別表記） | CHEMICAL STUDY ON SEKIGANE HOT SPRINGS, TOTTORI-KEN |
| フルテキストURL | pitsr_029_038_049.pdf |
| 著者 | 阪上 正信| 御船 政明| |
| 抄録 | The chemical and physical characteristics of the thermal and ground waters in Sekigane Hot Springs were determined. The content of the following chemical constituents was determined: Cl(-), S0(4)(2-), HCO(3)(-), Ca(2+), As, F, U and Ra. The relationship between water temperature and depth of spring wens was found to be indicative of the presence of a fissure, in agreement with the conclusion reached geologically by Sugiyama. The water temperature, the e1ectricconductivity and the content of chemical constituents of the ground water were as expected markedly lower than those of the thermal water. As a whole, however, the water temperature, the electricconductivity and the content of SO(4)(2-), HCO(3)(-), Ca(2+), As and F are in positive and linear correlation with the Cl- content. In other words, these characteristics of the waters, excluding the U and Ra content, correlate positively and linearly with each other. This was interpreted to mean that a thermal water of high salinity is simply diluted by a cold ground water of very low salinity, and that a ground water of relatively high salinity is contaminated by thermal water. The content of U and Ra of these spring waters is lower than that of the spring waters in Ikeda, Shimane-ken, and Misasa, Tottori-ken, where radioactive springs also issue. Finally, it is concluded that As and F will be as useful as Cl- in chemically locating a new site for a spring well in Sekigane because of the low contamination due to human life of ground water by these elements. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1961-06-25 |
| 巻 | 29巻 |
| 開始ページ | 38 |
| 終了ページ | 49 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/21348 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462882 |
| JaLCDOI | 10.18926/40220 |
|---|---|
| タイトル（別表記） | Study on the Separation of Uranium by Ion Exchage |
| フルテキストURL | pitsr_029_007_019.pdf |
| 著者 | 梅本 春次| 渡辺 昌介| |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1961-06-25 |
| 巻 | 29巻 |
| 開始ページ | 7 |
| 終了ページ | 19 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462881 |
| JaLCDOI | 10.18926/40212 |
|---|---|
| タイトル（別表記） | A Clinical Investigation of the Gastric Acidity of 113 Patients with Cholecystopathy |
| 著者 | 仲原 泰博| 大谷 満| |
| 抄録 | In order to investigate the relationship between gastric acidity and various clinical and labolatory test findings in patients with cholecystopathy, the authors studied the case records of 113 such patients treated at this institute. The results obtained were as follows. 1) Concerning gastric acidity, 13,6%, of the 113 patients showed hyperacidity; 11,1%, normal acidity; 33, 0%, hypoacidity; and 42,3%, anacidity. 2) A higher percentage of cases showing low gastric acidity was found among those patients with a longer history of the disease. 3) Cases evencing lower level of gastric acidity tended to be characterized by a higher frequency of abnormal laboratory findings and clinical symptoms. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1962-04-25 |
| 巻 | 30巻 |
| 開始ページ | 72 |
| 終了ページ | 76 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40213 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532377 |
| JaLCDOI | 10.18926/40211 |
|---|---|
| フルテキストURL | pitsr_030_066_071.pdf |
| 著者 | 北山 稔| 桑田 昭| 河田 義郎| |
| 抄録 | The authors gathered 78 cases of gouty arthritis reported in Japan between 1898 and 1960, and analysed them statistically. 1. The incidence of gouty arthritis appears to have increased since about the end of the 2nd World War, especially since 1955. 2. The age of the presumptive onset of the disease is lower in Japanese than in white populations. 3. In many cases, the gouty patients were wrongly diagnosed as rheumatoid arthritis, synovitis or panaritium patients, and only 20 per cent of the cases examined were diagnosed correctly at the first consultation. The author stresses that diagnosis at an early stage is necessary to avoid serious complications such as cardiovascular and renal involvements. If the condition is satisfactorily controlled by diets and drugs, however, the prognosis for gouty patients is excellent. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1962-04-25 |
| 巻 | 30巻 |
| 開始ページ | 66 |
| 終了ページ | 71 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002401091 |
| JaLCDOI | 10.18926/40210 |
|---|---|
| タイトル（別表記） | Clinical Studies on Gout 1st Report: Five Cases of Gouty Arthritis |
| 著者 | 北山 稔| 桑田 昭| 河田 義郎| |
| 抄録 | Five cases of gouty arthritis encountered in the clinic of Branch Hospital of Okayama University at Misasa Spa are described. Case 1: Y.I., a man aged 58, was first seen on April 24, 1961. His first symptoms had occurred 10 years previously, when he was awakened by severe pain in the left instep. The attack resolved within a few days, but since that time he had 2 or 3 attacks of acute arthritis each year, at first restricted to the dorsum of his left foot, near the base of the big toe, but later involving the ankles and the knees. These attacks usually lasted about a week, but recently such attacks had become more frequent and tended to last longer. In early January, 1961, he noticed pain and swelling of the fingers and consulted this clinic for the purpose of obtaining balneotherapy. A tophaceous mass the size of walnut was presnt on the left olecranon. Nine determinations of the blood uric-acid level were made, ranging from 8.1 to 10.1 mg. per 100 ml. The serum cholesterol level was 279 mg. per 100 ml. Treatment combining the use of phenylbutazone and balneothenapy was effective. Case 2: J.K., a man aged 80, was first seen on July 25, 1961. For 4 years he had been subject to attacks of acute arthritis affecting the fingers and toes. On July 16, he had sudden severe pain in the instep of the left foot. His son had probable gout. The metatarso-phalangeal joint of the left big toe was swollen and painful. The blood uric-acid level was 10.1 mg. per 100 ml. Treatment combined the use of phenylbutazone, dietary regulation, and the drinking of radioactive spring water. In Oct. 1961, he wrote saying that he had remained free from symptoms of gout and had no further treatment. Case 3: I.M., a man aged 52, was first seen on January 24, 1962. His symptoms began in 1935 (at the age of 25), when he had sudden severe pain in his right big toe, which rapidly became swollen and red. The pain lasted about a month. After this, he had at least one similar attack of joint pain in each of the next 10 years. In 1945, he noticed a pain in the dorsum of his right foot. The attacks have tended to last longer and to involve multiple joints, most recently the knees and hands being also affected. He was treated for rheumatoid arthritis and hypercholesterolemia. About the middle of January, 1962, the swelling which had first appeared on his right foot in 1935 became very painful and was accompanied by fever (38.°5～39.℃.). There was no family history of gout. The metatarso-phalangeal joint of the right big toe was swollen and painful, and the right knee was swollen. Determinations of the blood uric-acid level ranged from 5.5 to 12.0 mg. per 100 ml. The serum cholesterol level was 196 mg. per 100 ml. Therapy with phenylbutazone was started on January 24, 1962, in a total daily dose of 200 mg. and by the middle of Feburary, symptoms had disappeared. He discontinued use of the medication, whereupon a recurrent attack appeared. For the first few days he was given phenylbutazone, 400 mg. daily. This dosage was later reduced to 300 mg. daily, and benemid was added. Case 4: Y.U., a man aged 57, was first seen on Feburary 12, 1962. For 8 years he had been subject to attacks of acute arthritis affecting both insteps. Swelling and limited movement were present in the big toes. He had aural tophi. The blood uric-acid level was 8.2 mg. per 100 ml. Case 5: B.A., a man aged 67, was first seen on April 10, 1962. His first relevant symptoms had occurred 3 years previously, when he developed sudden pain and swelling in his right big toe. The pain lasted about 5 days. Since then he had had similar attacks at the rate of five a year. In March, 1962, he had an attack of joint pain in the right ankle lasting 5 days. The blood uric-acid levels ranged from 5.0 to 9.3 mg. per 100 ml. Administration of phenylbutazone, 200 mg. daily, and balneotherapy relieved the symptoms of gouty arthritis. The Use of balneotherapy in the treatment of chronic gouty arthritis will be discussed in a second paper by the present authors in the next volume of this series. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1962-04-25 |
| 巻 | 30巻 |
| 開始ページ | 55 |
| 終了ページ | 65 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532379 |
| JaLCDOI | 10.18926/40208 |
|---|---|
| タイトル（別表記） | A Statistical and Clinical Study of Postoperative Intestinal Adhesions |
| フルテキストURL | pitsr_030_040_045.pdf |
| 著者 | 大谷 満| |
| 抄録 | The author studied 36 cases of postoperative intestinal adhesions treated in this insitute during the past ten years. The results obtained were as follow. 1) The sex ratio was 21 (male) to 15 (female). 2) Fifty-three percent of the cases ranged from 20 to 40 years in age. 3) The initial operations which supposedly caused the adhesions were appendectomies. 4) Of the primary causative disease of the acute intetinal obstruction group, appendicitis accounted for 62% and gastrointestinal diseases for 15.4%. The primary causative disease of the chronic intestinal obstruction group was found to be appendicitis in about 70% of the cases. 5) The chief complaints made by patients were of vomiting and generalized Severe pain of the abdomen. 6) The most frequent sites of occurrence of the adhesions were the greater omentum, the small intestine and the sutured part of the peritoneum. 7) As regards the final therapeutic approach, in the largest number of cases (36.% of the total) lysis of the adhesion was performed. In most other cases, however, distress was relieved by enterostomy, resection of the bowel, and so on. Finally, the four most recent cases, all of whom suffered from recurrent intestinal obstrution, were relieved of the major portion of their abdominal complaints by a new method, an improvement of the original technique advocated by Noble in 1937. The details of this new technique will be reported in the next issue. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1962-04-25 |
| 巻 | 30巻 |
| 開始ページ | 40 |
| 終了ページ | 45 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002401089 |
| JaLCDOI | 10.18926/40205 |
|---|---|
| タイトル（別表記） | Balneological Studies of Kaike Hot Springs (I) Effect of the Internal Use of Kaike Spring Water on Gastric Acidity |
| フルテキストURL | pitsr_030_014_019.pdf |
| 著者 | 河田 義郎| |
| 抄録 | Kaike Hot Spring is situated at the seaside, in the western part of Tottori Prefecture, Japan. In chemical composition it contains 9.3 g. of salts per kilogram of spring water and may be classified as a common salt spring. The author examined the effect of the drinking of Kaike spring water on gastric acidity in 21 patients. a) Two hundred m!. of this spring water were given to 10 patients by stomach tube at 37℃. The gastric acidity of the patients was measured at 30-minute intervals for a period of 105 minutes following the administration of the spring water. In 3 cases of normal acidity and 6 cases of hyperacidiy, the spring water appeared to inhibit the secretion of gastric acid, compared with the effect of the caffein control water. b) Two hundred m!. of the spring water diluted two-fold with tap water were given to 11 patients. In two cases of normal acidity and two cases of hypoacidity, on significant difference was observed between the effects of the spring water and those of the control water. In all 7 cases of hyperacidity, however, the spring water observably depressed the acid secretion of the stomach, as compared with the effect of the control water. On the basis of these results, the author concludes that it is advisable to use the spring water diluted two-fold with tap water for the purpose of treating gastric disorders. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1962-04-25 |
| 巻 | 30巻 |
| 開始ページ | 14 |
| 終了ページ | 19 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002401087 |
| JaLCDOI | 10.18926/40204 |
|---|---|
| タイトル（別表記） | Effect of Radioactive Hot Spring Baths on Leukocyte Functions (Wandering Velocity and Carbon-Particle Phagocytic Ability) |
| フルテキストURL | 030_001_013.pdf |
| 著者 | 井上 正勝| |
| 抄録 | The author studied the influence of a series of radioactive hot-spring baths, lasting 20 or 30 days, upon leukocyte functions in healthy male rabbits and in patients with rhenmatoid arthritis and other diseases. The radioactive hot springs used were "Hisui-no-Yu" and "Kenkyusho-sen" (the laboratory spring), both in Misasa Spa, the chemical compositions of which are deseribed in Table 1. The following results were obtained: 1) Wandering velocity of pseudo-neutrophilic leukocytes: When a series of plain water baths (41℃., for 5 minutes daily), were administered, velocity increased after the first bathing but later remained fairly constant, compared with initial levels, except for a temporary fall on the 9th day (Fig. 3). During the administration of a series of the weakly radioactive "Kenkyushosen" baths (43℃., for 5 minutes daily), it showed a slight increase during the first week, following a temporary fall after the first bathing, and a decrease during the third week, but it tended to return to the initial level by the forth week (Fig. 1). In the course of a series of the radioactive ·Hisui-no-Yu" baths (40℃., for 10 minutes daily), it increased during the first week and tended to decrease during the second week, but returned to the initial level by the third week (Fig. 2). 2) Phagocytic ability for carbon-particles of pseudo-neutrophic leukocytes in rabbits: When plain water baths were given, phagocytic ability showed a rise on the third day, after which it declined to the initial level and remained fairly constant to the end of the observation period (Fig. 6.). On the other hand, the phagocytic ability of the leukocytes in rabbits of the groups receiving radioactive hot-spring baths increased more and more markedly as serial bathing was continued, although it had slightly decreased immediately after the first bathing. The rise of phagocytic ability in the group bathed in "Kenkyusho-sen" was especially marked on the third and ninth days of serial bathing, and also on the tenth day after serial bathing had been discontinued (Fig. 4). This tendency was also observed in the group bathed in "Hisui-no-Yu", whose phagocytic ability was noticeable especially on the third and 14th days. The degree of the rise in phagocytic ability was demonstrably high in this group than in the former (Fig. 5). Acceleration of the phagocytic function of leukocytes in rabbits was observed up to the 40th day after the series of baths in the radioactive hot spring had been concluded. 3) From these findings. it is obvious that leukocyte function is increased by repeated bathing, but it should be kept in mind that a so-called dissociation phenomenon is present between the wandering velocity and the carbon-phagocytic ability of leukocytes in the groups bathed in hot springs: namely, wandering velocity showed a tendency to decline during the third week, while carbon particle phagocytic ability showed a marked increase during the same week. 4) In order to explore the effects of a series of radioactive hot-spring baths on leukocyte functions in patients with rheumatoid arthritis or other similar diseases (for example, back pain, fibrositis or neuritis), the author examined the wandering velocity and the phagocytic ability of neutrophils, and obtained the following results: The wandering velocity of neutrophils in patients with rheumatoid arthritis or similar diseases generally showed a tendency to increase during the adminlstration of a series of the radioactive "Kenkyusho-sen" baths at a temperature of 42～43℃. (Fig. 7). The carbon-particle phagocytic ability of neutrophils gradually increase from about the seventh day onward and reached a maximum during the second week, in patients with back pain, fibrositis and neuritis (Fig. 8a). In patients with rheumatoid arthritis, however, it declined temporarily on the fifth to seventh days in 3 out of 5 patients but thereafter increased gradually, reaching its maximum on the 20th day (Fig. 8b). Thus, the leukocyte functions in patients with rheumatoid arthritis are accelerated by serial bathing, but the response in some patients may be a decline of carbon-particle phagocytic ability during the first week. This is probably due to the stress bathing imposes on adrenocortical functions. It is believed, on the basis of the facts described above, that follow-up examinations of leucocyte functions can afford a better understanding of the effects of radioactive hot springs on the defence mechanisms operative in living bodies. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1962-04-25 |
| 巻 | 30巻 |
| 開始ページ | 1 |
| 終了ページ | 13 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40213 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532380 |
| JaLCDOI | 10.18926/40200 |
|---|---|
| タイトル（別表記） | Epidemiological study of the prevalence of rheumatic disorders in rural districts in Tottori Prefecture, Japan |
| フルテキストURL | 036_041_053.pdf |
| 著者 | 江沢 英光| |
| 抄録 | Epidemiological evaluation of rural population samples of Misasa, Tomari and Kofu villages in Tottori Prefecture, Japan (Fig. 1), for occurance of rheumatic disorders was performed. This region has an annual rainfall of about 80 inches. The principal occupations are farming, and fishery in part. 1. One thousand six hundreds and twenty-seven persons, age 30 and over were investigated by clinical and serological means. In this preliminary communication the prevalence of probable and definite rheumatoid arthritis, accoding to defined by the A.R.A. criteria, was 1.04% and low back pain-sciatic pain, arthralgia and painful shoulder (cervical spondylosis and so on) were 8.4, 8.9 and 7.1% respectively (Table 2 and 4). 2. Serum samples from residents in Misasa- and Tomari-districts were obtained and rheumatoid factor was tested by means of RA-test (Hyland Laboratories). The incidence of positive test was 3.2% in 407 males and 5.0% in 715 females, but there is no significant difference between the two. Concerning the effect of age, there was a general tendency for the proportion of positive test to be greatest in the older age groups (Fig. 2). 3. Serum uric acid concentrations of 230 males and 395 females were measured by the modified method of Folin-Wu (latron-kit-method). The mean serum uric acid concentration (with standard deviation) was found to be 4.02±0.18mg. per 100ml. for males and 3.38±0.13mg. per 100ml. for females (Fig. 3 and 4), and the differecne between the two was significant. The author found no gouty patient in this papulation survey. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1966-10-25 |
| 巻 | 36巻 |
| 開始ページ | 41 |
| 終了ページ | 53 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532335 |
| JaLCDOI | 10.18926/40197 |
|---|---|
| タイトル（別表記） | Minor elements of the Nanbu Kotai of Nakatsugo Deposits, Ningyo Toge Uranium Mine |
| フルテキストURL | pitsr_036_023_030.pdf |
| 著者 | 渡辺 晃二| |
| 抄録 | The Nakatsugo Deposits are the main deposits of the Ningyo Toge Mine which is located in the northern part of Okayama Prefecture. Nakatsugo Deposits consists of the two main ore body, namely, Nanbu Kotai (southern ore body) and Hon Kotai (main ore body). Nanbu Kotai is occupied mostly by the unoxidized zone and high grade ores containing ningyoite (n% U) are widely found in the basal conglomerates. Minor elements in the common rocks such as basal granites, conglomerates, sandstones, dikes, and shales as well as the uraniferous ores were determined quantatively by fluorescent X-ray spectrometric analysis (for U, Zr, Y, Sr, As, and Fe) and spectrophotometric analysis (for Ni and Co). As the results of this study, it is found that the uraniferous ores are characterised by extremely high contents of Zr, Y, Sr, and As, which show positive and linear correlation with the U contents. It is confirmed that As is concentrated in pyrite which is usually associated with the uraniferous ores. Elements such as Ni and Co are slightly concentrated both in the uraniferous ores and andesite dikes. This fact may suggest some genetic relationship among them. However, it does not seem to be plausible to draw any definite conclusion on the origin of the uranium deposits from these relationships. As to the minor element distribution in common rocks, no systematic variation was found except for the rock samples closely associated with the ore deposits. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1966-10-25 |
| 巻 | 36巻 |
| 開始ページ | 23 |
| 終了ページ | 30 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002400933 |