検索結果 18718 件
| JaLCDOI | 10.18926/AMO/54420 |
|---|---|
| フルテキストURL | 70_3_205.pdf |
| 著者 | Kozaki, Ken-ichi| Kawakami, Shigehisa| Konishi, Takayuki| Ohta, Keiji| Yano, Jitsuro| Onoda, Tomoo| Matsumoto, Hiroshi| Mizukawa, Nobuyoshi| Kimata, Yoshihiro| Nishizaki, Kazunori| Iida, Seiji| Gofuku, Akio| Abe, Masanobu| Minagi, Shogo| Okayama Dream Speech Project| |
| 抄録 | A palatal augmentation prosthesis (PAP) is used to facilitate improvement in the speech and swallowing functions of patients with tongue resection or tongue movement disorders. However, a PAPʼs effect is limited in cases where articulation disorder is severe due to wide glossectomy and/or segmental mandibulectomy. In this paper, we describe speech outcomes of a patient with an articulation disorder following glossectomy and segmental mandibulectomy. We used a palatal plate (PP) based on a PAP, along with an artificial tongue (KAT). Speech improvement was evaluated by a standardized speech intelligibility test consisting of 100 syllables. The speech intelligibility score was significantly higher when the patient wore both the PP and KAT than when he wore neither (p＝0.013). The conversational intelligibility score was significantly improved with the PP and KAT than without PP and KAT (p＝0.024). These results suggest that speech function can be improved in patients with hard tissue defects with segmental mandibulectomy using both a PP and a KAT. The nature of the design of the PP and that of the KAT will allow these prostheses to address a wide range of tissue defects. |
| キーワード | palatal augmentation prosthesis artificial tongue articulation disorder glossectomy mandibulectomy |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-06 |
| 巻 | 70巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 205 |
| 終了ページ | 211 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27339210 |
| Web of Science KeyUT | 000379406100008 |
| JaLCDOI | 10.18926/AMO/54419 |
|---|---|
| フルテキストURL | 70_3_197.pdf |
| 著者 | Takagi, Kosei| Yagi, Takahito| Yoshida, Ryuichi| Shinoura, Susumu| Umeda, Yuzo| Nobuoka, Daisuke| Kuise, Takashi| Watanabe, Nobuyuki| Sui, Kenta| Fuji, Tomokazu| Fujiwara, Toshiyoshi| |
| 抄録 | The operative mortality and morbidity of pancreaticoduodenectomy (PD) remain high. We analyzed PD patientsʼ clinical characteristics and surgical outcomes and discuss how PD clinical outcomes could be improved. We retrospectively reviewed the cases of 400 patients who underwent a PD between January 1998 and April 2014 at Okayama University Hospital, a very-high-volume center. We identified and compared the clinical outcomes between two time periods (period 1: 1998-2006 vs. period 2: 2007-2014). The total postoperative mortality and major complication rates were 0.75 and 15.8 , respectively, and the median postoperative length of stay (LOS) was 32 days. Subsequently, patients who underwent a PD during period 2 had a significantly shorter LOS than those who underwent a PD during period 1 (29 days vs. 38.5 days, p＜0.001). The incidence of mortality and major complications did not differ between the two periods. In our multivariate analysis, period 1 was an independent factor associated with a long LOS (p＜0.001). The improvement of the surgical procedure and perioperative care might be related to the shorter LOS in period 2 and ot the consistently maintained low mortality rate after PD. The development of multimodal strategies to accelerate postoperative recovery may further improve PDʼs clinical outcomes. |
| キーワード | pancreaticoduodenectomy surgical outcome mortality major complication length of stay |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-06 |
| 巻 | 70巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 197 |
| 終了ページ | 203 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27339209 |
| Web of Science KeyUT | 000379406100007 |
| JaLCDOI | 10.18926/AMO/54418 |
|---|---|
| フルテキストURL | 70_3_189.pdf |
| 著者 | Fujiwara, Hiroyasu| Arai, Yasuaki| Ishii, Hiroaki| Kanazawa, Susumu| |
| 抄録 | We retrospectively evaluated the safety and efficacy of artificial pneumothorax induction to perform computed tomography (CT)-guided radiofrequency ablation (RFA) for sub-diaphragm hepatocellular carcinomas (HCCs). From June 2008 to October 2010 at our institution, 19 HCCs (16 patients) were treated using CT-guided RFA after artificial pneumothorax induction. A 23-G needle was inserted into the liver surface at a site of 2 connected pleurae without lung tissue. After a small amount of air was injected, the pleural space widened, creating a small pneumothorax. Additional air was insufflated via a newly inserted 18-G cannula to raise the lung away from the planned puncture line for RFA. The electrode was then advanced transthoracically. Ablation was performed using a cool-tip electrode with manual impedance control mode. The injected air was then aspirated as much as possible. Artificial pneumothorax was successfully induced in all cases. The average total volume of injected air in each case was 238ml. No artificial pneumothorax-related complication occurred; lung injury occurred in one case during RF electrode insertion. No local progression occurred during follow-up. Recurring HCCs were observed in eight patients. Artificial pneumothorax induction is safe and effective for CT-guided RFA of sub-diaphragm HCCs, which are difficult to locate on US. |
| キーワード | hepatocellular carcinoma liver radiofrequency ablation CT fluoroscopy artificial pneumothorax |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-06 |
| 巻 | 70巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 189 |
| 終了ページ | 195 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27339208 |
| Web of Science KeyUT | 000379406100006 |
| JaLCDOI | 10.18926/AMO/54416 |
|---|---|
| フルテキストURL | 70_3_175.pdf |
| 著者 | Setiawan, Heri| Nagaoka, Kenjiro| Kubo, Masayuki| Fujikura, Yoshihisa| Ogino, Keiki| |
| 抄録 | Oxidative stress is widely known to play a role in asthma. However, the contribution of xanthine oxidoreductase (XOR) as a source of the superoxide anion radical (O2－) in oxidative stress associated with asthma has not yet been examined in detail. Here we investigated pathophysiological changes in XOR in an experimental model of asthma induced by the house dust mite Dermatophagoides farinae (Df). In the lungs of Df-treated mice, the production of O2－ from XOR increased and the nitrite concentrations decreased, whereas the protein expression of XOR remained unchanged. Moreover, the protein expression levels of XOR and the hydrogen peroxide (H2O2) concentrations in bronchoalveolar lavage fluid (BALF) were higher in the Df-treated mice than in saline-treated mice. Immunohistochemically, although XOR was highly localized in the bronchial epithelial cells of the saline-treated mice, immunostaining for XOR was absent in the bronchial epithelium of Df-treated mice. These results suggest that oxidative stress is up-regulated by increases in the conversion of the dehydrogenase form (xanthine dehydrogenase; XDH) of XOR to the oxidase form (xanthine oxidase; XOD). |
| キーワード | xanthine oxidase oxidative stress asthma |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-06 |
| 巻 | 70巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 175 |
| 終了ページ | 182 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27339206 |
| Web of Science KeyUT | 000379406100004 |
| JaLCDOI | 10.18926/AMO/54415 |
|---|---|
| フルテキストURL | 70_3_167.pdf |
| 著者 | Sugihara, Satoshi| Doi, Hiroyuki| Kato, Masahiko| Mitoh, Yoshihiro| Tsuda, Toshihide| Ikeda, Satoru| |
| 抄録 | Aflatoxin (AFT) contamination is frequent in foods grown in tropical regions, including rice. Although AFTs are generally not found in temperate-region foods, global warming has affected typical temperate-region climates, potentially permitting the contamination of foods with AFT-producing Aspergillus flavus (A. flavus). Here we investigated the AFT production in rice during storage under natural climate conditions in Japan. We examined AFTs in brown rice and rough rice artificially contaminated with A. flavus for 1 year in Japan, and we subjected AFTs in white rice to the same treatment in airtight containers and examined the samples in warm and cold seasons, simulating the storage of white rice in general households. In the brown rice, AFTs increased after 2 months (March) and peaked after 9 months (October). The AFT contamination in the rough rice was minimal. After the polishing and cooking of the brown rice, AFTs were undetectable. In the white rice stored in airtight containers, AFTs increased after 1 month (August) and peaked after 2 months (September). Minimal AFTs were detected in the cold season. Thus, AFT contamination in rice may occur in temperate regions following A. flavus contamination. The storage of rice as rough rice could provide be useful for avoiding AFT contamination. |
| キーワード | Aspergillus flavus aflatoxin rice temperate region storage |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-06 |
| 巻 | 70巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 167 |
| 終了ページ | 173 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27339205 |
| Web of Science KeyUT | 000379406100003 |
| JaLCDOI | 10.18926/AMO/54414 |
|---|---|
| フルテキストURL | 70_3_159.pdf |
| 著者 | Yoshioka, Takashi| Otsuki, Hideo| Uehara, Shinya| Shimizu, Toshihiro| Murao, Wataru| Fujio, Koji| Fujio, Kei| Wada, Koichiro| Araki, Motoo| Nasu, Yasutomo| |
| 抄録 | Upper urinary tract calculi are common; however, there is no recommended treatment selection for elderly patients. Ureteroscopic holmium laser lithotripsy (URS lithotripsy) is minimally invasive, and it provides a high stone-free rate (SFR) treatment for upper urinary tract calculi. Here, we retrospectively evaluated the surgical outcomes of URS lithotripsy after dividing the 189 cases into 3 groups by patient age: the ʻ＜65 groupʼ (＜65 years old, n＝108), the ʻ65-74 groupʼ (65-74 years old, n＝42), and the ʻ 75 groupʼ ( 75 years old, n＝39). The patientsʼ characteristics, stone status, and perioperative outcomes were assessed. The 65-74 group and the 75 group had a significantly higher prevalence of hypertension compared to the＜65 group. Compared to the＜65 group, the 65-74 group had a significantly higher prevalence of hyperlipidemia, and the 75 group had significantly higher the American Society of Anesthesiologists (ASA) scores. Despite these preoperative risk factors, SFR and postoperative pyelonephritis in the 65-74 group and the 75 group were similar to those of the＜65 group. In conclusion, URS lithotripsy is the preferred treatment for upper urinary tract calculi, even for elderly patients who have multiple preoperative risk factors. |
| キーワード | upper urinary tract calculi ureteroscopy (URS) holmium laser lithotripsy elderly patients stone-free rate (SFR) |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-06 |
| 巻 | 70巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 159 |
| 終了ページ | 166 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27339204 |
| Web of Science KeyUT | 000379406100002 |
| 著者 | 工藤 季之| |
|---|---|
| 発行日 | 2016-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 32巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 樅木 勝巳| |
|---|---|
| 発行日 | 2016-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 32巻 |
| 資料タイプ | その他 |
| 著者 | 加藤 内藏進| 加藤 晴子| 赤木 里香子| 稲田 佳彦| |
|---|---|
| 発行日 | 2016-02 |
| 出版物タイトル | 環境制御 |
| 巻 | 37巻 |
| 資料タイプ | 紀要論文 |
| フルテキストURL | ACA_924_60.pdf |
|---|---|
| 著者 | Karita, Shingo| Kaneta, Takashi| |
| キーワード | Chelate titration Microfluidic paper-based analytical device Hardness Calcium Magnesium Natural water |
| 備考 | © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/| |
| 発行日 | 2016-06-14 |
| 出版物タイトル | Analytica Chimica Acta |
| 巻 | 924巻 |
| 出版者 | Elsevier B.V. |
| 開始ページ | 60 |
| 終了ページ | 67 |
| ISSN | 0003-2670 |
| NCID | AA00524834 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2016 Elsevier B.V. |
| 論文のバージョン | author |
| PubMed ID | 27181645 |
| DOI | 10.1016/j.aca.2016.04.019 |
| Web of Science KeyUT | 000375747700008 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.aca.2016.04.019 |
| フルテキストURL | K0005355_abstract_review.pdf K0005355_fulltext.pdf |
|---|---|
| 著者 | 峯野 雅博| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5355号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（工学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005346_abstract_review.pdf K0005346_fulltext.pdf |
|---|---|
| 著者 | MD. EZHARUL ISLAM| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5346号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（工学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005301_abstract_review.pdf K0005301_fulltext.pdf K0005301_summary.pdf |
|---|---|
| 著者 | 後藤田 達洋| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5301号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005299_abstract_review.pdf K0005299_fulltext.pdf |
|---|---|
| 著者 | 伊藤 英史| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5299号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005297_abstract_review.pdf K0005297_fulltext.pdf |
|---|---|
| 著者 | HERI SETIAWAN| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5297号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005296_abstract_review.pdf K0005296_fulltext.pdf |
|---|---|
| 著者 | 時信 亜希子| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5296号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005292_abstract_review.pdf K0005292_fulltext.pdf |
|---|---|
| 著者 | 諏澤 憲| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5292号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005291_abstract_review.pdf K0005291_fulltext.pdf K0005291_summary.pdf |
|---|---|
| 著者 | 伊藤 麻衣子| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5291号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005285_abstract_review.pdf K0005285_fulltext.pdf |
|---|---|
| 著者 | 野坂 宜之| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5285号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005284_abstract_review.pdf K0005284_fulltext.pdf |
|---|---|
| 著者 | 河野 吉泰| |
| 発行日 | 2016-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5284号 |
| 学位授与年月日 | 2016-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |