| ID | 67339 |
| 著者 |
Sasaki, Hinako
Department of Radiological Technology, Faculty of Health Sciences, Okayama University Medical School
Morishita, Takumi
Department of Radiological Technology, Faculty of Health Sciences, Okayama University Medical School
Irie, Naho
Department of Radiological Technology, Faculty of Health Sciences, Okayama University Medical School
Kojima, Rena
Department of Radiological Technology, Faculty of Health Sciences, Okayama University Medical School
Kiriyama, Tetsukazu
Department of Radiology, Uwajima City Hospital
Nakamoto, Akira
Department of Radiology, Tokuyama Central Hospital
Nishioka, Kunio
Department of Radiology, Tokuyama Central Hospital
Takahashi, Shotaro
Department of Radiology, Tokuyama Central Hospital
Tanabe, Yoshinori
Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
ORCID
Kaken ID
researchmap
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| 抄録 | Accurate information on set-up error during radiotherapy is essential for determining the optimal number of treatments in hypofractionated radiotherapy for prostate cancer. This necessitates careful control by the radiotherapy staff to assess the patient's condition. This study aimed to develop an evaluation method of the temporal trends in a patient's specific prostate movement during treatment using image matching and margin values. This study included 65 patients who underwent prostate volumetric modulated arc therapy (mean treatment time, 87.2 s). Set-up errors were assessed using bone, inter-, and intra-fraction marker matching across 39 fractions. The set-up margin was determined by dividing the four periods into 39 fractions using Stroom's formula and correlation coefficient. The intra-fraction set-up error was biased in the anterior-superior (AS) direction during treatment. The temporal trend of set-up errors during radiotherapy slightly increased based on bone matching and inter-fraction marker matching, with a 1.6-mm difference in the set-up margin fractions 11 to 20. The correlation coefficient of the mean prostate movement during treatment significantly decreased in the superior-inferior direction, while remaining high in the left-right and anterior-posterior directions. Image matching contributed significantly to the improvement of set-up errors; however, careful attention is needed for prostate movement in the AS direction, particularly during short treatment times. Understanding the trend of set-up errors during the treatment period is essential in numerical information sharing on patient condition and evaluating the margins for tailored hypo-fractionated radiotherapy, considering the facility's image-guided radiation therapy technology.
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| キーワード | Hypofractionated radiotherapy
Image-guided radiation therapy
Prostate cancer
Prostate movement
Set-up margin
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| 備考 | © 2024 American Association of Medical Dosimetrists. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
This fulltext file will be available in Oct. 2025.
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| 発行日 | 2024-03-30
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| 出版物タイトル |
Medical Dosimetry
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| 巻 | 49巻
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| 号 | 4号
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| 出版者 | Elsevier
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| 開始ページ | 291
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| 終了ページ | 297
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| ISSN | 0958-3947
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| 資料タイプ |
学術雑誌論文
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| 言語 |
英語
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| OAI-PMH Set |
岡山大学
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| 著作権者 | © 2024 American Association of Medical Dosimetrists.
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| 論文のバージョン | publisher
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| PubMed ID | |
| DOI | |
| Web of Science KeyUT | |
| 関連URL | isVersionOf https://doi.org/10.1016/j.meddos.2024.02.004
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| ライセンス | https://creativecommons.org/licenses/by-nc-nd/4.0/
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| 助成機関名 |
Japan Society for the Promotion of Science
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| 助成番号 | JP23K07063
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