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JaLCDOI 10.18926/okadaironkou/59998
フルテキストURL okadaironkou_45_38_50.pdf
著者 渡辺 健|
出版物タイトル 岡大国文論稿
発行日 2017-03-31
45号
開始ページ 38
終了ページ 50
ISSN 0386-3123
言語 日本語
論文のバージョン publisher
NAID 40021262946
フルテキストURL fulltext.pdf
著者 Katsuyama, Eri| Miyawaki, Yoshia| Sada, Ken-Ei| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Hiramatsu-Asano, Sumie| Morishita, Michiko| Ohashi, Keiji| Watanabe, Haruki| Katsuyama, Takayuki| Narazaki, Mariko| Matsumoto, Yoshinori| Wada, Jun|
キーワード Lupus nephritis Active lesions Chronic lesions Urinary protein Serum creatinine
発行日 2020-06-01
出版物タイトル BMC Nephrology
21巻
1号
出版者 BMC
開始ページ 208
ISSN 1471-2369
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s). 2020
論文のバージョン publisher
PubMed ID 32487161
DOI 10.1186/s12882-020-01868-9
Web of Science KeyUT 000538054600002
関連URL isVersionOf https://doi.org/10.1186/s12882-020-01868-9
JaLCDOI 10.18926/AMO/59949
フルテキストURL 74_3_191.pdf
著者 Ohashi, Keiji| Sada, Ken-Ei| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Asano, Sumie Hiramatsu| Miyawaki, Yoshia| Morishita, Michiko| Katsuyama, Eri| Watanabe, Haruki| Tatebe, Noriko| Narazaki, Mariko| Matsumoto, Yoshinori| Sunahori-Watanabe, Katsue| Kawabata, Tomoko| Yajima, Nobuyuki| Wada, Jun|
抄録 Chronic damage accumulation affects not only mortality but also quality of life in patients with systemic lupus erythematosus (SLE). Risk factors for chronic damage were explored in SLE through different onset eras. Two hundred forty-five patients at Okayama University Hospital and Showa University Hospital were divided into three groups based on the onset era: a past-onset group (onset before 1995; n=83), middle-onset group (1996-2009; n=88), and recent-onset group (after 2010; n=74). The mean Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) score as an index of chronic damage was 1.93, 1.24, and 0.53 in the past-, middle-, and recent-onset groups, respectively. In the pastonset group, the total SDI score was significantly associated with glucocorticoid monotherapy by linear regression analysis (β-coefficient [β]=0.63; 95% confidence interval [CI], 0.21-1.05) and C-reactive protein levels (β=0.67; 95% CI, 0.27-1.07). In the middle-onset group, the total SDI score was significantly associated with the SLE Disease Activity Index at registration (β=0.09; 95% CI, 0.03-0.12). Reducing the accumulation of chronic damage in SLE patients might be possible with the concomitant use of immunosuppressants and tight control of disease activity.
キーワード systemic lupus erythematosus chronic damage glucocorticoids, disease activity disease duration
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-06
74巻
3号
出版者 Okayama University Medical School
開始ページ 191
終了ページ 198
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32577016
Web of Science KeyUT 000543363400002
NAID 120006862791
フルテキストURL 00-鹿田遺跡目次等.pdf 01-鹿田遺跡 第1章.pdf 02-鹿田遺跡 第2章.pdf 03-鹿田遺跡 第3章.pdf 04-鹿田遺跡 第4章.pdf 05-鹿田遺跡 第5章.pdf 06-鹿田遺跡遺構一覧表.pdf 07-鹿田遺跡-図版.pdf 08-鹿田遺跡報告抄録.pdf
著者 山口 雄治| 南 健太郎| 岩﨑 志保| 渡辺 正巳| 能城 修一| 沖 陽子| 江川 達也|
出版物タイトル 岡山大学構内遺跡発掘調査報告
発行日 2019-03-29
35巻
言語 日本語
論文のバージョン publisher
Pages 89p. 20図版
フルテキストURL JCR25_4_45.pdf Fig.pdf
著者 Motokura, Yumi| Watanabe, Haruki| Yamamura, Yuriko| Kano, Yuzuki| Matsumoto, Yoshinori| Kawabata, Tomoko| Sada, Ken-ei| Wada, Jun|
発行日 2019-06
出版物タイトル Journal of Clinical Rheumatology
25巻
4号
出版者 Lippincott, Williams & Wilkins
開始ページ 45
終了ページ 47
ISSN 1076-1608
NCID AA11016642
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 29470260
DOI 10.1097/RHU.0000000000000723
Web of Science KeyUT 000470908400007
関連URL isVersionOf https://doi.org/10.1097/RHU.0000000000000723
フルテキストURL SR9_1_3054.pdf
著者 Hiramatsu, Sumie| Watanabe, Katsue S.| Zeggar, Sonia| Asano, Yosuke| Miyawaki, Yoshia| Yamamura, Yuriko| Katsuyama, Eri| Katsuyama, Takayuki| Watanabe, Haruki| Takano-Narazaki, Mariko| Matsumoto, Yoshinori| Kawabata, Tomoko| Sada, Ken-Ei| Wada, Jun|
発行日 2019-2-28
出版物タイトル Scientific Reports
9巻
出版者 Nature Publishing Group
開始ページ 3054
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2019
論文のバージョン publisher
PubMed ID 30816218
DOI 10.1038/s41598-019-38809-y
Web of Science KeyUT 000459891700064
関連URL isVersionOf https://doi.org/10.1038/s41598-019-38809-y
フルテキストURL K0005653_abstract_review.pdf K0005653_summary.pdf K0005653_ fulltext.pdf
著者 渡辺 晴樹|
発行日 2018-03-23
資料タイプ 学位論文
学位授与番号 甲第5653号
学位授与年月日 2018-03-23
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
著者 Putri, Arrival Rince| Nova, Tertia Delia| Watanabe, Masaji|
発行日 2016
出版物タイトル AIP Conference Proceedings
1707巻
資料タイプ 会議発表論文
著者 Wardhani, Puteri Kusuma| Watanabe, Masaji|
発行日 2016
出版物タイトル AIP Conference Proceedings
1707巻
資料タイプ 会議発表論文
タイトル(別表記) Adenocarcinoma in the jejunum 20 years after surgery for familial adenomatous polyposis
フルテキストURL 129_111.pdf
著者 杉原 雄策| 川野 誠司| 原田 馨太| 高嶋 志保| 竹井 大介| 井口 俊博| 高原 政宏| 平岡 佐規子| 母里 淑子| 岸本 浩行| 永坂 岳司| 岡田 裕之|
抄録 A 58-year-old Japanese man visited a local clinic for the evaluation of a stomachache. He was diagnosed with intestinal obstruction. His medical history included a proctocolectomy at the age of 38 years, due to familial adenomatous polyposis (FAP). He was referred to our institution, where he underwent a computed tomography examination and endoscopy of the small intestine. The pathological diagnosis was adenocarcinoma. No invasive or metastatic lesions were observed. Therefore, partial resection of the ileum with lymphadenectomy and reconstruction of the ileostomy were performed. Pathological examination revealed that the tumor was type 2, pT3 (SS) , pN1, pPM0, pDM0, pRM0, INFb, ly1, v1, pEX0, PN0. Twenty-nine days after the surgery, the patient was diagnosed with lung metastasis and he underwent lung radiofrequency ablation. We suggest that long-term follow-up is necessary for patients after surgery for FAP, because of the risk of malignant disease developing in other organs.
キーワード 家族性大腸腺腫症 (familial adenomatous polyposis) 小腸癌 (jejunal cancer) 小腸内視鏡検査 (small intestine endoscope)
出版物タイトル 岡山医学会雑誌
発行日 2017-08-01
129巻
2号
開始ページ 111
終了ページ 114
ISSN 0030-1558
関連URL https://doi.org/10.4044/joma.129.111
言語 日本語
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.111
NAID 130006039373
タイトル(別表記) Changes of colonic mucosa caused by long-term use and discontinuation of anthraquinone
フルテキストURL 129_23.pdf
著者 岩野 英二| 岩室 雅也| 岡田 裕之|
抄録 Anthraquinone, an anthracene derivatives, is widely used as a purgative medicine. The long-term use of anthraquinone is known to cause melanosis coli and elevated lesions in the colon. However, the clinical course of patients who take anthraquinone over a long term and those who discontinue the drug has not been fully investigated. Here we investigated 22 patients who had colonic mucosal changes ( i.e., melanosis coli and elevated lesions) who had been taking anthraquinone for at least one year and discontinued it. We classified the elevated lesions into two subtypes:the small-lesion, which included multiple small nodules that were < 2 mm in dia., and the large-lesion, which included a single or multiple nodules of ≥ 2-mm dia. We used colonoscopy to investigate the changes of colonic lesions between before and after the discontinuation of anthraquinone. The results indicated that the nodules of the small-lesion group were lymphoid follicle hyperplasia. In the large-lesion group, adenoma was most frequently observed ( n=118) , followed by hyperplastic polyp ( n=52) and inflammatory changes with edema ( n=22) . Melanosis coli and elevated lesions were decreased or invisible after the discontinuation of anthraquinone. Our findings thus suggest that the long-term use of anthraquinone may cause some type of elevated lesions due to chronic inflammation. It is recommended that the use of anthraquinone be limited to a short term.
キーワード アントラセン誘導体(anthracene derivatives) アントラキノン(anthraquinone) 大腸黒皮症(melanosis coli) 大腸メラノーシス(pseudomelanosis coli) リンパ濾胞過形成(lymphoid follicle hyperplasia)
出版物タイトル 岡山医学会雑誌
発行日 2017-04-03
129巻
1号
開始ページ 23
終了ページ 30
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.23
NAID 130005632078
タイトル(別表記) Behçetʼs disease complicated by ileocecal and esophageal perforation
フルテキストURL 128_27.pdf
著者 九十九 悠太| 河本 和幸| 高木 弘誠| 陳 開| 松葉 優里| 長久 吉雄| 岡部 道雄| 白川 靖博| 伊藤 雅| 藤原 俊義|
抄録  A 36-year-old Japanese man known to have incomplete Behçet’s disease (oral aphthous ulcers, genital ulcers, skin lesions, and esophageal and ileocecal ulcers) was admitted to our hospital in January 2011 for abdominal pain. We administered corticosteroids and immunosuppressants. Two months later, we performed an ileocecal resection to control gastrointestinal bleeding from the ileocecal ulcers. High fever persisted after this surgery, and upper gastrointestinal endoscopy demonstrated ulcer penetration between the lower and abdominal esophagus. Eighteen days after the initial ileocecal resection, we performed a lower esophagus resection, gastric tube reconstruction and enterostomy, during which we confirmed a 5-mm-dia. perforated site at the posterior wall of the abdominal esophagus. Postoperative anastomotic leakage and empyema occurred, but they were relieved by thoracic drainage and empyema dissection.
キーワード ベーチェット病(Behçet’s disease) 食道(esophagus) 回盲部(ileocecal) 穿孔(perforation) 手術(surgery)
出版物タイトル 岡山医学会雑誌
発行日 2016-04-01
128巻
1号
開始ページ 27
終了ページ 32
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.128.27
言語 日本語
著作権者 Copyright (c) 2016 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.128.27
NAID 130005149603
タイトル(別表記) A case of mucinous adenocarcinoma of the duodenum and literature review of 16 cases reported in Japan
フルテキストURL 128_21.pdf
著者 浜野 郁美| 松本 祐介| 遠藤 芳克| 渡邊 直樹| 甲斐 恭平| 佐藤 四三| 和仁 洋治|
抄録  Primary mucinous adenocarcinoma of the duodenum is rare. Here we report a case we recently encountered, and we review 16 cases reported in Japan. An 82-year-old Japanese woman was admitted to our hospital complaining of abdominal pain and heartburn. An endoscopic examination revealed a Type 2 tumor in the descending limb of the duodenum, and endoscopically obtained specimens revealed a poorly differentiated adenocarcinoma. We performed a curative pancreatoduodenectomy with lymph node resection, and the surgical specimen revealed that the duodenum was the primary site of the mucinous adenocarcinoma. The patient is currently alive > 1 year after the operation without any evidence of recurrence. Of the 16 patients reviewed, all patients had advanced tumors those depth were T3-T4. 9 patients had lymph node metastasis and 4 patients had peritoneal dissemination at the time of surgery. Since mucinous adenocarcinoma of the duodenum is often progressive cancer at a diagnosis, which is tend to have a worse prognosis than other histological types.
キーワード 原発性十二指腸癌(primary duodenal cancer) 粘液癌(mucinous carcinoma) 膵頭十二指腸切除(pancreatoduodenectomy)
出版物タイトル 岡山医学会雑誌
発行日 2016-04-01
128巻
1号
開始ページ 21
終了ページ 25
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.128.21
言語 日本語
著作権者 Copyright (c) 2016 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.128.21
NAID 130005149602
タイトル(別表記) Drug-induced liver injury due to the long-term oral administration of rosuvastatin
フルテキストURL 127_219.pdf
著者 大西 理乃| 狩山 和也| 湧田 暁子| 西村 守| 能祖 一裕|
抄録 A 67-year-old man was admitted to our hospital presenting with a liver injury. He had used several types of oral medication for the prior 2 years, including rosuvastatin calcium for hypertension, hyperlipidemia, and prostatic hypertrophy. His liver dysfunction was noted for the first time in February 2013, and at re-examination in March 2013 he showed exacerbation of the liver dysfunction, he was admitted to our hospital at that time. We stopped all of his oral medications, and his liver function improved steadily. We conducted a drug-induced lymphocyte transformation test (DLST), and the rosuvastatin calcium result was positive. He was diagnosed as having a drug-induced (by rosvastatin calcium) liver injury. He resumed oral medications other than rosuvastatin calcium from the time of discharge, with no exacerbation of liver dysfunction since then. Reports of drug-induced liver injury due to drugs with a long-term oral administration are extremely rare. We discuss the relevant literature herein.
キーワード 薬物性肝障害(drug induced liver injury) ロスバスタチンカルシウム(Rosuvastatin) スタチン(statin) DLST
出版物タイトル 岡山医学会雑誌
発行日 2015-12-01
127巻
3号
開始ページ 219
終了ページ 222
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.219
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.219
NAID 130005116815
タイトル(別表記) Non-high-output cardiac failure in patients undergoing hemodialysis through an arteriovenous shunt
フルテキストURL 127_203.pdf
著者 鵜川 豊世武|
抄録 Background: Hemodialysis-related heart failure has been considered to be associated with excessive blood flow through the arteriovenous (AV) shunt used for vascular access. However, some patients undergoing dialysis have heart failure in the absence of an increase in cardiac output (CO) related to shunt blood-flow loading because the loading cannot be compensated for by increasing CO. This condition may be challenging to manage ; thus, early diagnosis is important. Methods and Results: Twelve patients (mean age, 71 years ; 9 men) with end-stage renal disease, dialysis-related heart failure, a high brain natriuretic peptide (BNP) level, and a mean New York Heart Association (NYHA) class of II underwent AV shunt closure. Their cardiac index (CI), pre- and post-dialysis BNP levels, and several cardiac variables were assessed pre- and postoperatively. All patients achieved relief of heart failure symptoms and a reduction in NYHA class after AV closure, but six patients had a postoperative increase in CI (the "non-high-output" cardiac failure group), whereas the other six had a decrease in CI (the "high-output" cardiac failure group). The high-output patients had greater improvements in BNP levels and most cardiac variables compared to the non-high-output group ; therefore, the heart failure in the non-high-output patients was considered more serious than that in the high-output group. Conclusions: The selection of effective strategies for treating dialysis-related heart failure may depend partly on identifying which patients have non-high-output failure. Such identification requires serial measurements of BNP levels and evaluations of cardiac variables other than the ejection fraction.
キーワード 心拍出量(cardiac output) 心不全(heart failure) 脳性ナトリウム利尿ペプチド(brain natriuretic peptide) 非過大シャント心不全(non-high-output cardiac failure) 腎臓(kidney)
出版物タイトル 岡山医学会雑誌
発行日 2015-12-01
127巻
3号
開始ページ 203
終了ページ 207
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.203
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.203
NAID 130005116810
著者 永井 伊作| Yamauchi, Genki| Nagatani, Keiji| Watanabe, Keigo| Yoshida, Kazuya|
発行日 2013-07-22
出版物タイトル Advanced Robotics
27巻
15号
資料タイプ 学術雑誌論文
著者 永井 伊作| Watanabe, Keigo|
発行日 2015-09-28
出版物タイトル IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)
資料タイプ 会議発表論文
タイトル(別表記) Successful laparoscopic resection of a cecal tumor in a 95-year-old man
フルテキストURL 127_117.pdf
著者 渡邉 彩子| 稲田 涼| 永坂 岳司| 八木 朝彦| 松本 聖| 戸嶋 俊明| 菊池 覚次| 黒田 新士| 近藤 喜太| 母里 淑子| 岸本 浩行| 藤原 俊義|
抄録 We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials (RCTs) revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients.
キーワード 超高齢者(extremely elderly patient) 大腸癌(colorectal cancer) 腹腔鏡手術(laparoscopic surgery)
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
127巻
2号
開始ページ 117
終了ページ 121
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.117
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.117
NAID 130005096253
フルテキストURL K0005075 abstract_review.pdf K0005075_fulltext.pdf
著者 渡辺 雅子|
発行日 2015-03-25
資料タイプ 学位論文
学位授与番号 甲第5075号
学位授与年月日 2015-03-25
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
タイトル(別表記) Okayama University Survey of the current situation of community-based medical facilities supported by part-time work by physicians
フルテキストURL 127_13.pdf
著者 勅使川 早苗| 岩瀬 敏秀| 金森 達也| 川畑 智子| 佐藤 勝| 片岡 仁美|
抄録  We investigated the situation of how physicians at Okayama University support local medical institutions by serving as a part-time worker, and analyzed the difference between the five medical districts of Okayama prefecture and other prefectures. Many physicians (actual number of physicians, full-time equivalent number of physicians) served in the southeastern region of the Okayama prefecture (339, 82.2). On the other hand, fewer physicians (42, 11.4) served in Takahashi・Niimi in the northwestern region of Okayama. Many physicians also served in Hiroshima prefecture (193, 48.8), Hyogo prefecture (109, 26.7), and the four prefectures of Shikoku Island (81, 23.6).  It has been clarified that many physicians at Okayama University are working on a part-time basis to support local and community medical institutions in the wide area of Okayama prefecture, Hiroshima prefecture, Hyogo prefecture and the four prefectures of Shikoku Island.
キーワード 岡山大学勤務医師(physicians at Okayama University) 非常勤勤務(part-time worker) 地域医療機関支援(community-based medical facilities)
出版物タイトル 岡山医学会雑誌
発行日 2015-04-01
127巻
1号
開始ページ 13
終了ページ 17
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.13
NAID 130005068345