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dt-accepted=
dt-pub-year=2025
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en-title=Market Reactions to Earnings Announcements in Profitable and Loss Firm-Quarters: Changes Around the Market Restructuring
kn-title=�•ŽšŠé‹Æ‚Æ�ÔŽšŠé‹Æ‚É‚¨‚¯‚錈ŽZ”­•\‚ɑ΂·‚éŽs�ê‚Ì”½‰ž�\Žs�ê‹æ•ª•Ï�X‘OŒã‚É‚¨‚¯‚镪�Í�\
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kn-subtitle=
en-abstract=
kn-abstract=The purpose of this paper is to examine whether the market reaction to earnings announcements in each market segment �iprime market segment, standard market segment, and growth market segment�j differs between profitable and loss-making firms around the time of market restructuring. We have previously studied market reactions to quarterly earnings announcements in the context of the revision of market segmentation at the Tokyo Stock Exchange. However, we have not studied the differences between profitable firm quarters and loss firm quarters. Therefore, the analysis in this paper focuses on whether the net income attributable to owners of the parent is positive or negative. In the growth market segment, significant differences between profitable and loss-making firms were observed in the results of the analysis.
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en-aut-name=NakagawaToyotaka
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en-aut-name=YamanishiYuki
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en-aut-name=KobayashiHiroaki
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affil-num=2
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affil-num=3
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kn-affil=�ÂŽRŠw‰@‘åŠw‘åŠw‰@‰ïŒvƒvƒ�ƒtƒFƒbƒVƒ‡ƒ“Œ¤‹†‰È
END

start-ver=1.4
cd-journal=joma
no-vol=56
cd-vols=
no-issue=3
article-no=
start-page=1
end-page=13
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250321
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Market Segmentation and Market Reactions to Earnings Announcements: A Quarterly Analysis
kn-title=Žs�ê‹æ•ª‚ÆŒˆŽZ”­•\‚ɑ΂·‚éŽs�ê‚Ì”½‰ž �\Žl”¼Šúƒf�[ƒ^‚ð—˜—p‚µ‚½•ª�Í�\
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The purpose of this paper is to examine, using quarterly financial data, how the market reaction to earnings announcements in each market segment �iprime market segment, standard market segment, and growth market segment�j has changed after the revision of market segmentation at the Tokyo Stock Exchange. For the research design, the abnormal volume and residual returns for the 12 quarters around April 1, 2022, when the market segmentation was changed, were calculated using the analysis method of Beaver et al. �m2020�n. The results of the analysis suggest that volume is significantly affected by changes in market segmentation. In addition, for the group of stocks in the growth market, there appears to have been some change in the trend of stock price fluctuations after the market segmentation revision.
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en-aut-name=NakagawaToyotaka
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en-aut-name=YamanishiYuki
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en-aut-name=KobayashiHiroaki
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dt-pub=20170315
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en-title=Newsletter from Course for Prospective Museum Workers, Faculty of Letters, Okayama University
kn-title=ŠwŒ|ˆõ‰Û’ö Newsletter ‘æ8�†
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kn-affil=•¶Šw•”—ðŽj•¶‰»Šw�ê�CƒR�[ƒX

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kn-affil=•¶Šw•”“NŠwŒ|�pŠw�ê�CƒR�[ƒX

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cd-journal=joma
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article-no=
start-page=33
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dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240329
dt-online=
en-article=
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kn-subject=
en-title=The Role of Teachers in the Development of Play Using Grasses and Flowers in a Kindergarten Class for 4-year-olds
kn-title=—c’t‰€‚S�ÎŽ™Šw‹‰‚É‚¨‚¯‚é‘�‰Ô‚ðŽg‚Á‚½—V‚Ñ‚Ì“WŠJ‚ÉŒ©‚鋳Žt‚Ì–ðŠ„
en-subtitle=
kn-subtitle=
en-abstract=This paper aims to organize and examine the role of teachers in the play using grasses and flowers in a kindergarten class for 4-year-olds. In early childhood education, harmonious and diverse learning deepens and develops alongside the development of play, with play and learning seemingly occurring spontaneously and child-directed. However, the roles of teachers, such as �genvironmental constitution anticipating the child's presence,�h �gmaintenance of the physical environment in accordance with changes in play,�h and �gbridging to the development of play,�h were identified as underlying the background of the development of play and learning.
kn-abstract=�@–{˜_‚Í�C—c’t‰€‚S�ÎŽ™Šw‹‰‚É‚¨‚¯‚é‘�‰Ô‚ðŽg‚Á‚½—V‚Ñ‚É‚¨‚¢‚Ä�C‹³Žt‚Ì–ðŠ„‚ð�®—�‚µ�C�lŽ@‚·‚é‚à‚Ì‚Å‚ ‚é�B—cŽ™‹³ˆç‚Å‚Í�C—V‚Ñ‚Ì“WŠJ‚É”º‚Á‚Ä�C’²˜a“I‚Å‘½—l‚ÈŠw‚Ñ‚ª�[‰»�E”­“W‚µ�C—V‚Ñ‚âŠw‚Ñ‚Í�C—cŽ™Žå‘Ì‚Å‹ô”­“I‚É�¶‚¶‚Ä‚¢‚é‚悤‚ÉŒ©‚¦‚é�B‚µ‚©‚µ�C—V‚Ñ‚Ì“WŠJ‚âŠw‚Ñ‚Ì”wŒi‚É‚Í�C�u—cŽ™‚ÌŽp‚ð—\‘z‚µ‚½ŠÂ‹«�\�¬�v�u—V‚Ñ•û‚̕ω»‚É�‡‚킹‚½•¨“IŠÂ‹«‚Ì�®”õ�v�u—V‚Ñ‚Ì”­“W‚ւ̉˂¯‹´�v‚Æ‚¢‚Á‚½‹³Žt‚Ì–ðŠ„‚ªŒ©�o‚³‚ꂽ�B
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en-aut-name=TAKAHASHIToshiyuki
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affil-num=1
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affil-num=2
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affil-num=4
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en-keyword=‘�‰Ô—V‚Ñ (play using grasses and flowers)
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en-keyword=—V‚Ñ‚Ì“WŠJ‚ÆŠw‚Ñ (development of play and learning)
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cd-journal=joma
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article-no=
start-page=327
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dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230330
dt-online=
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en-title=Diverse Learning of Children that Can Be Observed during Developing Play with Flowers in the Class of Kindergarten for Four-year-old Children
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en-abstract=The purpose of this paper is to clarify the development of play in early childhood education. The learning in childhood is diverse and comprehensive therefore it was difficult to capture the complete picture and it has been empirically understood. Accordingly, we considered play with flowers in the class of kindergarten for four-year-old children. As their play was developed, the learning was deepened, developed, and related to five fields of childcare contents. In addition, the background of learning in childhood that seemed incidental involved effective approaches by te achers.
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en-aut-name=NISHIMURA (NAKAGAWA)Kana
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en-aut-name=TakahashiToshiyuki
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affil-num=1
en-affil=Social welfare corporation Tachibana kai Minan Manmaru childcare center
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affil-num=2
en-affil=Former The Kindergarten Attached to the Faculty of Education, Okayama University
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cd-journal=joma
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en-title=Market Reaction to More Informative Earnings Announcements
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en-aut-name=NakagawaToyotaka
en-aut-sei=Nakagawa
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start-ver=1.4
cd-journal=joma
no-vol=54
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dt-accepted=
dt-pub-year=2022
dt-pub=20220729
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kn-subject=
en-title=Preliminary Study of the Relationship Between Accounting Fundamentals and Stock Prices for the Prime Market
kn-title=ƒvƒ‰ƒCƒ€Žs�ê‚ð‘Î�Û‚Æ‚µ‚½‰ïŒv‚̃tƒ@ƒ“ƒ_ƒ�ƒ“ƒ^ƒ‹ƒY‚ÆŠ”‰¿‚ÌŠÖŒW‚ÉŠÖ‚·‚é—\”õ“IŒ¤‹†
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kn-subtitle=
en-abstract=
kn-abstract=The purpose of this paper is to examine the relationship between accounting fundamentals and future abnormal returns for prime market issues on the Tokyo Stock Exchange. The background of the study is the revision of market segmentation in Japan starting April 2022. To elaborate, the market classification on the Tokyo Stock Exchange has been reorganized from the four categories of�g First Section,�h�g Second Section,�h�g Mothers,�h and�g JASDAQ�h to three categories of�g Prime Market,�h�g Standard Market,�h and�g Growth Market.�h By examining the relationship between accounting fundamentals and future abnormal returns for prime market stocks, this paper provides empirical evidence on how the introduction of this new market classification affects the relationship between value based on accounting fundamentals and stock prices.
en-copyright=
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en-aut-name=NakagawaToyotaka
en-aut-sei=Nakagawa
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en-aut-name=YamanishiYuki
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affil-num=2
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kn-abstract= The purpose of this paper is to examine fundamental analysis from an accounting perspective and clarify its value and significance. For that purpose, I focus on quantitative investment strategies, capital market research in accounting, accounting anomalies, mispricing, and research paths. Fundamental analysis is one of the important directions in empirical accounting research that has been studied since Ball and Brown�i 1968�j. Fundamental analysis influences neighboring research areas, and thus it should not be ignored or downplayed in accounting research because of the dissemination of quantitative investment strategies.
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kn-title=Current Treatment Strategies and Nanoparticle-Mediated Drug Delivery Systems for Pulmonary Arterial Hypertension
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kn-abstract=There are three critical pathways for the pathogenesis and progression of pulmonary arterial hypertension (PAH): the prostacyclin (prostaglandin I-2) (PGI(2)), nitric oxide (NO), and endothelin pathways. The current approved drugs targeting these three pathways, including prostacyclin (PGI(2)), phosphodiesterase type-5 (PDE5) inhibitors, and endothelin receptor antagonists (ERAs), have been shown to be effective, however, PAH remains a severe clinical condition and the long-term survival of patients with PAH is still suboptimal. The full therapeutic abilities of available drugs are reduced by medication, patient non-compliance, and side effects. Nanoparticles are expected to address these problems by providing a novel drug delivery approach for the treatment of PAH. Drug-loaded nanoparticles for local delivery can optimize the efficacy and minimize the adverse effects of drugs. Prostacyclin (PGI(2)) analogue, PDE5 inhibitors, ERA, pitavastatin, imatinib, rapamycin, fasudil, and oligonucleotides-loaded nanoparticles have been reported to be effective in animal PAH models and in vitro studies. However, the efficacy and safety of nanoparticle mediated-drug delivery systems for PAH treatment in humans are unknown and further clinical studies are required to clarify these points.
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affil-num=8
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kn-subject=
en-title=Preliminary Study on Classification of Financial Ratios Using Factor Analysis
kn-title=ˆöŽq•ª�Í‚É‚æ‚é�à–±”ä—¦‚Ì•ª—Þ‚ÉŠÖ‚·‚é—\”õ“IŒ¤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The purpose of this paper is to perform factor analysis on financial ratios calculated using consolidated financial statement data from the fiscal year ended March 31, 2006 to the fiscal year ended March 31, 2017, which are disclosed by Japanese companies, and to classify financial ratios.<br/>
�@The analysis provided evidence to suggest that both net income and cash flows from operating activities are functioned as financial performance measures with similar properties. We also find that capital efficiency is an important factor. Furthermore, there is also evidence that cash flows from investing activities and cash flows from financing activities have a common factor.
en-copyright=
kn-copyright=

en-aut-name=NakagawaToyotaka
en-aut-sei=Nakagawa
en-aut-mei=Toyotaka
kn-aut-name=’†�ì–L—²
kn-aut-sei=’†�ì
kn-aut-mei=–L—²
aut-affil-num=1
ORCID=

en-aut-name=NagahataHidekazu
en-aut-sei=Nagahata
en-aut-mei=Hidekazu
kn-aut-name=’·”¨�G˜a
kn-aut-sei=’·”¨
kn-aut-mei=�G˜a
aut-affil-num=2
ORCID=

en-aut-name=YamanishiYuki
en-aut-sei=Yamanishi
en-aut-mei=Yuki
kn-aut-name=ŽR�¼—C‹G
kn-aut-sei=ŽR�¼
kn-aut-mei=—C‹G
aut-affil-num=3
ORCID=

affil-num=1
en-affil=Graduate School of Humanities and Social Sciences, Okayama University
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ŽÐ‰ï•¶‰»‰ÈŠwŒ¤‹†‰È

affil-num=2
en-affil=Graduate School of Humanities and Social Sciences, Okayama University
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ŽÐ‰ï•¶‰»‰ÈŠwŒ¤‹†‰È

affil-num=3
en-affil=
kn-affil=ŒF–{Œ§—§‘åŠw‘��‡ŠÇ—�Šw•”
END

start-ver=1.4
cd-journal=joma
no-vol=47
cd-vols=
no-issue=
article-no=
start-page=93
end-page=111
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190322
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The Key Factors of Growth over the Industry Lifecycle
kn-title=ƒ‰ƒCƒtƒTƒCƒNƒ‹‚ð�l—¶‚µ‚½Šé‹Æ‚Ì�¬’·—vˆö
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=KoshidaTakahisa
en-aut-sei=Koshida
en-aut-mei=Takahisa
kn-aut-name=‰z“c�F‹v
kn-aut-sei=‰z“c
kn-aut-mei=�F‹v
aut-affil-num=1
ORCID=

en-aut-name=NakagawaToyotaka
en-aut-sei=Nakagawa
en-aut-mei=Toyotaka
kn-aut-name=’†�ì–L—²
kn-aut-sei=’†�ì
kn-aut-mei=–L—²
aut-affil-num=2
ORCID=

en-aut-name=NagahataHidekazu
en-aut-sei=Nagahata
en-aut-mei=Hidekazu
kn-aut-name=’·”¨�G˜a
kn-aut-sei=’·”¨
kn-aut-mei=�G˜a
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ŽÐ‰ï•¶‰»‰ÈŠwŒ¤‹†‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ŽÐ‰ï•¶‰»‰ÈŠwŒ¤‹†‰È

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ŽÐ‰ï•¶‰»‰ÈŠwŒ¤‹†‰È
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20180323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=�^‹Û“ñŽŸ‘ãŽÓŽY•¨‚Å‚ ‚é(+)-terrein‚ªƒ}ƒEƒX�œ�‘—R—ˆƒ}ƒNƒ�ƒtƒ@�[ƒW‚É‚¨‚¢‚ÄRANKL—U“±�«”j�œ�×–E•ª‰»‚É‹y‚Ú‚·‰e‹¿‚Æ•W“I•ªŽq‚̉ð–¾
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaSaki
en-aut-sei=Nakagawa
en-aut-mei=Saki
kn-aut-name=’†�ì�¹‹I
kn-aut-sei=’†�ì
kn-aut-mei=�¹‹I
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È
END

start-ver=1.4
cd-journal=joma
no-vol=166
cd-vols=
no-issue=
article-no=
start-page=31
end-page=40
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20171128
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An Attempt to Analyze the Transformation in the Concept of the Environment during Class Practice for a Childcare Contents �gEnvironment�h
kn-title=•Ûˆç“à—e�uŠÂ‹«�v‚ÌŽö‹ÆŽÀ‘H‚É‚¨‚¯‚é ŠÂ‹«ŠT”O‚Ì•Ï—e‚𑨂¦‚鎎‚Ý
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=�@�gEnvironment? has special meanings in early childhood education and care in Japan. The present study, we identified characteristic that is a problem faced by students in understanding the concept of the environment in a class on child care in the context of the �genvironment? in a training school for child care providers. Specifically, this study used a sentence completion test to detect the transformation in the concept of environment in the students. These data were quantitatively analyzed using text mining. In addition, we examined the transformation in the environmental concept qualitatively. As a result, the tendency to use the captured environment as a method was seen, and some characteristics became clear. Based on these findings, we considered it necessary for class improvement to be expedited.
en-copyright=
kn-copyright=

en-aut-name=NishiyamaOsamu
en-aut-sei=Nishiyama
en-aut-mei=Osamu
kn-aut-name=�¼ŽR�C
kn-aut-sei=�¼ŽR
kn-aut-mei=�C
aut-affil-num=1
ORCID=

en-aut-name=OkamuraSachiyo
en-aut-sei=Okamura
en-aut-mei=Sachiyo
kn-aut-name=‰ª‘º�K‘ã
kn-aut-sei=‰ª‘º
kn-aut-mei=�K‘ã
aut-affil-num=2
ORCID=

en-aut-name=NakagawaTomoyuki
en-aut-sei=Nakagawa
en-aut-mei=Tomoyuki
kn-aut-name=’†�ì’q”V
kn-aut-sei=’†�ì
kn-aut-mei=’q”V
aut-affil-num=3
ORCID=

en-aut-name=KatayamaMika
en-aut-sei=Katayama
en-aut-mei=Mika
kn-aut-name=•ÐŽR”ü��
kn-aut-sei=•ÐŽR
kn-aut-mei=”ü��
aut-affil-num=4
ORCID=

affil-num=1
en-affil=Graduate School of Education, Okayama University
kn-affil=‰ªŽR‘åŠw‘åŠw‰@‹³ˆçŠwŒ¤‹†‰È

affil-num=2
en-affil=Graduate School of Education, Okayama University
kn-affil=‰ªŽR‘åŠw‘åŠw‰@‹³ˆçŠwŒ¤‹†‰È

affil-num=3
en-affil=Graduate School of Education, Okayama University
kn-affil=‰ªŽR‘åŠw‘åŠw‰@‹³ˆçŠwŒ¤‹†‰È

affil-num=4
en-affil=Graduate School of Education, Okayama University
kn-affil=‰ªŽR‘åŠw‘åŠw‰@‹³ˆçŠwŒ¤‹†‰È
END

start-ver=1.4
cd-journal=joma
no-vol=129
cd-vols=
no-issue=2
article-no=
start-page=111
end-page=114
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20170801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Adenocarcinoma in the jejunum 20 years after surgery for familial adenomatous polyposis
kn-title=‰Æ‘°�«‘å’°‘BŽî�Ç�pŒã20”NŒã‚É�¬’°Šà‚ð”­�Ç‚µ‚½1—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 58-year-old Japanese man visited a local clinic for the evaluation of a stomachache. He was diagnosed with intestinal obstruction. His medical history included a proctocolectomy at the age of 38 years, due to familial adenomatous polyposis (FAP). He was referred to our institution, where he underwent a computed tomography examination and endoscopy of the small intestine. The pathological diagnosis was adenocarcinoma. No invasive or metastatic lesions were observed. Therefore, partial resection of the ileum with lymphadenectomy and reconstruction of the ileostomy were performed. Pathological examination revealed that the tumor was type 2, pT3 (SS) , pN1, pPM0, pDM0, pRM0, INFb, ly1, v1, pEX0, PN0. Twenty-nine days after the surgery, the patient was diagnosed with lung metastasis and he underwent lung radiofrequency ablation. We suggest that long-term follow-up is necessary for patients after surgery for FAP, because of the risk of malignant disease developing in other organs.
en-copyright=
kn-copyright=

en-aut-name=SugiharaYuusaku
en-aut-sei=Sugihara
en-aut-mei=Yuusaku
kn-aut-name=�™Œ´—Y�ô
kn-aut-sei=�™Œ´
kn-aut-mei=—Y�ô
aut-affil-num=1
ORCID=

en-aut-name=KawanoSeiji
en-aut-sei=Kawano
en-aut-mei=Seiji
kn-aut-name=�ì–ì�½Ži
kn-aut-sei=�ì–ì
kn-aut-mei=�½Ži
aut-affil-num=2
ORCID=

en-aut-name=HaradaKeita
en-aut-sei=Harada
en-aut-mei=Keita
kn-aut-name=Œ´“cŠ]‘¾
kn-aut-sei=Œ´“c
kn-aut-mei=Š]‘¾
aut-affil-num=3
ORCID=

en-aut-name=TakashimaShiho
en-aut-sei=Takashima
en-aut-mei=Shiho
kn-aut-name=�‚“ˆŽu•Û
kn-aut-sei=�‚“ˆ
kn-aut-mei=Žu•Û
aut-affil-num=4
ORCID=

en-aut-name=TakeiDaisuke
en-aut-sei=Takei
en-aut-mei=Daisuke
kn-aut-name=’|ˆä‘å‰î
kn-aut-sei=’|ˆä
kn-aut-mei=‘å‰î
aut-affil-num=5
ORCID=

en-aut-name=InokuchiToshihiro
en-aut-sei=Inokuchi
en-aut-mei=Toshihiro
kn-aut-name=ˆäŒû�r”Ž
kn-aut-sei=ˆäŒû
kn-aut-mei=�r”Ž
aut-affil-num=6
ORCID=

en-aut-name=TakaharaMasahiro
en-aut-sei=Takahara
en-aut-mei=Masahiro
kn-aut-name=�‚Œ´�­�G
kn-aut-sei=�‚Œ´
kn-aut-mei=�­�G
aut-affil-num=7
ORCID=

en-aut-name=HiraokaSakiko
en-aut-sei=Hiraoka
en-aut-mei=Sakiko
kn-aut-name=•½‰ª�²‹KŽq
kn-aut-sei=•½‰ª
kn-aut-mei=�²‹KŽq
aut-affil-num=8
ORCID=

en-aut-name=MoriYoshiko
en-aut-sei=Mori
en-aut-mei=Yoshiko
kn-aut-name=•ê—¢�iŽq
kn-aut-sei=•ê—¢
kn-aut-mei=�iŽq
aut-affil-num=9
ORCID=

en-aut-name=KishimotoHiroyuki
en-aut-sei=Kishimoto
en-aut-mei=Hiroyuki
kn-aut-name=ŠÝ–{�_�s
kn-aut-sei=ŠÝ–{
kn-aut-mei=�_�s
aut-affil-num=10
ORCID=

en-aut-name=NagasakaTakeshi
en-aut-sei=Nagasaka
en-aut-mei=Takeshi
kn-aut-name=‰i�âŠxŽi
kn-aut-sei=‰i�â
kn-aut-mei=ŠxŽi
aut-affil-num=11
ORCID=

en-aut-name=OkadaHiroyuki
en-aut-sei=Okada
en-aut-mei=Hiroyuki
kn-aut-name=‰ª“c—T”V
kn-aut-sei=‰ª“c
kn-aut-mei=—T”V
aut-affil-num=12
ORCID=

affil-num=1
en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»Ší“à‰È

affil-num=2
en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»Ší“à‰È

affil-num=3
en-affil=Department of Gastroenterological Surgery, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@ŒõŠwˆã—Ã�f—Õ”

affil-num=4
en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»Ší“à‰È

affil-num=5
en-affil=Department of Gastroenterological Surgery, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@ŒõŠwˆã—Ã�f—Õ”

affil-num=6
en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»Ší“à‰È

affil-num=7
en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»Ší“à‰È

affil-num=8
en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»Ší“à‰È

affil-num=9
en-affil=Division of Endoscopy, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»ŠÇŠO‰È

affil-num=10
en-affil=Division of Endoscopy, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»ŠÇŠO‰È

affil-num=11
en-affil=Division of Endoscopy, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»ŠÇŠO‰È

affil-num=12
en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@�Á‰»Ší“à‰È
en-keyword=‰Æ‘°�«‘å’°‘BŽî�Ç (familial adenomatous polyposis)
kn-keyword=‰Æ‘°�«‘å’°‘BŽî�Ç (familial adenomatous polyposis)
en-keyword=�¬’°Šà (jejunal cancer)
kn-keyword=�¬’°Šà (jejunal cancer)
en-keyword=�¬’°“àŽ‹‹¾ŒŸ�¸ (small intestine endoscope)
kn-keyword=�¬’°“àŽ‹‹¾ŒŸ�¸ (small intestine endoscope)
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20170324
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=ŒÅ’è�«‰Ë�H‹`Ž•‚Ɖ“P�«•”•ª�°‹`Ž•‚ÌŽ¡—ÃŒø‰Ê”»’è‚Ì‚½‚ß‚ÌŒû�oŠÖ˜AQOLŽ¿–â•[‚Æ‚»‚Ì�Å�¬—LŒø�· : �Å�¬—LŒø�·‚Ì‘ª’è‚É‹y‚Ú‚·“VˆäŒø‰Ê‚ƃŒƒXƒ|ƒ“ƒXƒVƒtƒg‚̉e‹¿
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaShinsuke
en-aut-sei=Nakagawa
en-aut-mei=Shinsuke
kn-aut-name=’†�ì�W•ã
kn-aut-sei=’†�ì
kn-aut-mei=�W•ã
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=‰ªŽR‘åŠw‘åŠwˆãŽ•–òŠw‘��‡Œ¤‹†‰È
END

start-ver=1.4
cd-journal=joma
no-vol=128
cd-vols=
no-issue=3
article-no=
start-page=191
end-page=196
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20161201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Our experience with the significance of collaborative medical and dental surgeries at the Head and Neck Cancer Center, Okayama University Hospital
kn-title=‰ªŽR‘åŠw•a‰@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[‚É‚¨‚¯‚éˆã‰ÈŽ•‰È�‡“¯Žè�p‚ÌŒ»�ó‰ð�Í‚Æ‚»‚̈Ӌ`
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=�@�@We have been collaborating with head and neck surgeons, plastic surgeons and oral surgeons in surgeries for many patients with head and neck carcinomas�i especially oral carcinomas�j since 2006�i fiscal year 2005�j. The Head and Neck Cancer Center was established at Okayama University Hospital in 2012.
�@This Center was the first of its kind at a national university hospital in Japan.
�@At the Center, 174 operations on head and neck carcinomas and 96 reconstructive operations were performed in 2014�i fiscal year�j.
�@Medical and dental collaborative operations have been increasing almost every year since the 2005 fiscal year. There were 45 collaborative operations in the 2014 fiscal year, which included 30 cases of bone or metal plate reconstruction or plate reinforcement of the jaws.
�@There were 76 medical and dental collaborative operations in the 7 years before the establishment of the Center, with a mean of 10.9 operations per year. Since the establishment of the Center, there have been 112 cases over 3 years with a mean of 37.3 operations per year. The number of surgeries has been markedly increased by the establishment of the Head and Neck Cancer Center.
en-copyright=
kn-copyright=

en-aut-name=MizukawaNobuyoshi
en-aut-sei=Mizukawa
en-aut-mei=Nobuyoshi
kn-aut-name=�…�ì“W‹g
kn-aut-sei=�…�ì
kn-aut-mei=“W‹g
aut-affil-num=1
ORCID=

en-aut-name=OnodaTomoo
en-aut-sei=Onoda
en-aut-mei=Tomoo
kn-aut-name=�¬–ì“c—F’j
kn-aut-sei=�¬–ì“c
kn-aut-mei=—F’j
aut-affil-num=2
ORCID=

en-aut-name=MatsumotoHiroshi
en-aut-sei=Matsumoto
en-aut-mei=Hiroshi
kn-aut-name=�¼–{—m
kn-aut-sei=�¼–{
kn-aut-mei=—m
aut-affil-num=3
ORCID=

en-aut-name=TakedaSeiko
en-aut-sei=Takeda
en-aut-mei=Seiko
kn-aut-name=•�“c�ÄŽq
kn-aut-sei=•�“c
kn-aut-mei=�Ďq
aut-affil-num=4
ORCID=

en-aut-name=NodaYouhei
en-aut-sei=Noda
en-aut-mei=Youhei
kn-aut-name=–ì“c—m•½
kn-aut-sei=–ì“c
kn-aut-mei=—m•½
aut-affil-num=5
ORCID=

en-aut-name=OnodaSatoshi
en-aut-sei=Onoda
en-aut-mei=Satoshi
kn-aut-name=�¬–ì“c‘�
kn-aut-sei=�¬–ì“c
kn-aut-mei=‘�
aut-affil-num=6
ORCID=

en-aut-name=FukushimaMai
en-aut-sei=Fukushima
en-aut-mei=Mai
kn-aut-name=•Ÿ“‡–ƒˆß
kn-aut-sei=•Ÿ“‡
kn-aut-mei=–ƒˆß
aut-affil-num=7
ORCID=

en-aut-name=TsumuraMunechika
en-aut-sei=Tsumura
en-aut-mei=Munechika
kn-aut-name=’Ѻ�@‹ß
kn-aut-sei=’Ѻ
kn-aut-mei=�@‹ß
aut-affil-num=8
ORCID=

en-aut-name=TakeuchiTetsuo
en-aut-sei=Takeuchi
en-aut-mei=Tetsuo
kn-aut-name=’|“à“N’j
kn-aut-sei=’|“à
kn-aut-mei=“N’j
aut-affil-num=9
ORCID=

en-aut-name=SugiyamaNarushi
en-aut-sei=Sugiyama
en-aut-mei=Narushi
kn-aut-name=�™ŽR�¬Žj
kn-aut-sei=�™ŽR
kn-aut-mei=�¬Žj
aut-affil-num=10
ORCID=

en-aut-name=KimataYoshihiro
en-aut-sei=Kimata
en-aut-mei=Yoshihiro
kn-aut-name=–،Ҍh—T
kn-aut-sei=–ØŒÒ
kn-aut-mei=Œh—T
aut-affil-num=11
ORCID=

affil-num=1
en-affil=Departments of Oral and Maxillofacial Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�C Š{Œû�o�ÄŒšŠO‰È

affil-num=2
en-affil=Departments of Otorhinolaryngology, Head and Neck Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŽ¨•@ˆô�A�E“ªèò•”ŠO‰È

affil-num=3
en-affil=Departments of Plastic and Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŒ`�¬ŠO‰È

affil-num=4
en-affil=Departments of Oral and Maxillofacial Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŠ{Œû�o�ÄŒšŠO‰È

affil-num=5
en-affil=Departments of Otorhinolaryngology, Head and Neck Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŽ¨•@ˆô�A�E“ªèò•”ŠO‰È

affil-num=6
en-affil=Departments of Plastic and Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŒ`�¬ŠO‰È

affil-num=7
en-affil=Departments of Oral and Maxillofacial Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŠ{Œû�o�ÄŒšŠO‰È

affil-num=8
en-affil=Departments of Otorhinolaryngology, Head and Neck Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŽ¨•@ˆô�A�E“ªèò•”ŠO‰È

affil-num=9
en-affil=Departments of Dental Laboratory, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŽ•‰È‹Z�HŽº

affil-num=10
en-affil=Departments of Plastic and Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŒ`�¬ŠO‰È

affil-num=11
en-affil=Departments of Plastic and Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital
kn-affil=‰ªŽR‘åŠw•a‰@�@“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�CŒ`�¬ŠO‰È
en-keyword=“ªèò•”‚ª‚ñ�ihead and neck carcinoma�j
kn-keyword=“ªèò•”‚ª‚ñ�ihead and neck carcinoma�j
en-keyword=Œû�o‚ª‚ñ�ioral carcinoma�j
kn-keyword=Œû�o‚ª‚ñ�ioral carcinoma�j
en-keyword=“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�iHead and Neck Cancer Center�j
kn-keyword=“ªèò•”‚ª‚ñƒZƒ“ƒ^�[�iHead and Neck Cancer Center�j
en-keyword=ˆã‰ÈŽ•‰È�‡“¯Žè�p�icollaborative medical and dental surgeries�j
kn-keyword=ˆã‰ÈŽ•‰È�‡“¯Žè�p�icollaborative medical and dental surgeries�j
en-keyword=Š{�œ�ÄŒš�ireconstructive operations of the jaw�j
kn-keyword=Š{�œ�ÄŒš�ireconstructive operations of the jaw�j
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=5
article-no=
start-page=397
end-page=400
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=201610
dt-online=
en-article=
kn-article=
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kn-subject=
en-title=
kn-title=Feasibility of Repairing Defects Followed by Treatment with Pulmonary Hypertension-specific Drugs (Repair and Treat) in Patients with Pulmonary Hypertension Associated with Atrial Septal Defect: Study Protocol for Interventional Trial
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A treatment strategy for patients with pulmonary hypertension (PH) and atrial septal defect (ASD) remains unclear. This study was designed to evaluate the effects of initial repair of ASD followed by treatment with PH-specific drugs in patients with PH and ASD. Eligible patients receive transcatheter ASD closure followed by treatment with bosentan and sildenafil. Right heart catheterization is performed at baseline and at 12, 24 and 48 weeks. The primary endpoint is change in pulmonary artery pressure and pulmonary vascular resistance from baseline to follow-up. This study should provide valuable information to establish a therapeutic strategy for PH and ASD.
en-copyright=
kn-copyright=

en-aut-name=AkagiSatoshi
en-aut-sei=Akagi
en-aut-mei=Satoshi
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kn-aut-sei=
kn-aut-mei=
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ORCID=

en-aut-name=NakamuraKazufumi
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kn-aut-mei=
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ORCID=

en-aut-name=AkagiTeiji
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kn-aut-mei=
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en-aut-name=NakagawaKoji
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en-aut-name=TakayaYoichi
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en-aut-name=SarashinaToshihiro
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en-aut-name=EjiriKentaro
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aut-affil-num=7
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en-aut-name=ItoHiroshi
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kn-aut-mei=
aut-affil-num=8
ORCID=

affil-num=1
en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
kn-affil=

affil-num=2
en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
kn-affil=

affil-num=3
en-affil=Cardiac Intensive Care Unit, Okayama University Hospital
kn-affil=

affil-num=4
en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
kn-affil=

affil-num=5
en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
kn-affil=

affil-num=6
en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
kn-affil=

affil-num=7
en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
kn-affil=

affil-num=8
en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
kn-affil=
en-keyword=pulmonary hypertension
kn-keyword=pulmonary hypertension
en-keyword=atrial septal defect
kn-keyword=atrial septal defect
en-keyword=repair and treat
kn-keyword=repair and treat
en-keyword=transcatheter closure
kn-keyword=transcatheter closure
END

start-ver=1.4
cd-journal=joma
no-vol=47
cd-vols=
no-issue=3
article-no=
start-page=173
end-page=184
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20160319
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An Analysis of Accruals and Management Earnings Forecast Revisions
kn-title=‰ïŒv”­�¶�‚‚ÆŒo‰cŽÒ—\‘z—˜‰v‚Ì�C�³‚ÉŠÖ‚·‚镪�Í
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
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kn-copyright=

en-aut-name=NakagawaToyotaka
en-aut-sei=Nakagawa
en-aut-mei=Toyotaka
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kn-aut-mei=–L—²
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ORCID=

en-aut-name=YamanishiYuuki
en-aut-sei=Yamanishi
en-aut-mei=Yuuki
kn-aut-name=ŽR�¼—C‹G
kn-aut-sei=ŽR�¼
kn-aut-mei=—C‹G
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw

affil-num=2
en-affil=
kn-affil=ŒF–{Œ§—§‘åŠw
END

start-ver=1.4
cd-journal=joma
no-vol=47
cd-vols=
no-issue=2
article-no=
start-page=129
end-page=140
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20160223
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=What is Value Relevance?
kn-title=Value Relevance‚Ƃ͉½‚©
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaToyotaka
en-aut-sei=Nakagawa
en-aut-mei=Toyotaka
kn-aut-name=’†�ì–L—²
kn-aut-sei=’†�ì
kn-aut-mei=–L—²
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw
END

start-ver=1.4
cd-journal=joma
no-vol=128
cd-vols=
no-issue=1
article-no=
start-page=53
end-page=59
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20160401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Drug interaction (35. Opioid-analgesic drug interactions)
kn-title=–ò•¨‘ŠŒÝ�ì—p (35�\ƒIƒsƒIƒCƒh’Á’É–ò‚Ì–ò•¨‘ŠŒÝ�ì—p�j
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=SadaHikaru
en-aut-sei=Sada
en-aut-mei=Hikaru
kn-aut-name=�²“cŒõ
kn-aut-sei=�²“c
kn-aut-mei=Λ
aut-affil-num=1
ORCID=

en-aut-name=KajizonoMakoto
en-aut-sei=Kajizono
en-aut-mei=Makoto
kn-aut-name=’bŽ¡‰€�½
kn-aut-sei=’bŽ¡‰€
kn-aut-mei=�½
aut-affil-num=2
ORCID=

en-aut-name=KitamuraYoshihisa
en-aut-sei=Kitamura
en-aut-mei=Yoshihisa
kn-aut-name=–k‘º‰À‹v
kn-aut-sei=–k‘º
kn-aut-mei=‰À‹v
aut-affil-num=3
ORCID=

en-aut-name=SendoToshiaki
en-aut-sei=Sendo
en-aut-mei=Toshiaki
kn-aut-name=�ç“°”N�º
kn-aut-sei=�瓰
kn-aut-mei=”N�º
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ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw•a‰@�@–ò�Ü•”

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠw•a‰@�@–ò�Ü•”

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠw•a‰@�@–ò�Ü•”

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠw•a‰@�@–ò�Ü•”
END

start-ver=1.4
cd-journal=joma
no-vol=128
cd-vols=
no-issue=1
article-no=
start-page=21
end-page=25
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2016
dt-pub=20160401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of mucinous adenocarcinoma of the duodenum and literature review of 16 cases reported in Japan
kn-title=Œ´”­�«�\“ñŽw’°”S‰tŠà‚̈ê—á�\ –{–M•ñ��16—á‚ÌŒŸ“¢�\
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=�@Primary mucinous adenocarcinoma of the duodenum is rare. Here we report a case we recently encountered, and we review 16 cases reported in Japan. An 82-year-old Japanese woman was admitted to our hospital complaining of abdominal pain and heartburn. An endoscopic examination revealed a Type 2 tumor in the descending limb of the duodenum, and endoscopically obtained specimens revealed a poorly differentiated adenocarcinoma. We performed a curative pancreatoduodenectomy with lymph node resection, and the surgical specimen revealed that the duodenum was the primary site of the mucinous adenocarcinoma. The patient is currently alive �„ 1 year after the operation without any evidence of recurrence. Of the 16 patients reviewed, all patients had advanced tumors those depth were T3-T4. 9 patients had lymph node metastasis and 4 patients had peritoneal dissemination at the time of surgery. Since mucinous adenocarcinoma of the duodenum is often progressive cancer at a diagnosis, which is tend to have a worse prognosis than other histological types.
en-copyright=
kn-copyright=

en-aut-name=HamanoIkumi
en-aut-sei=Hamano
en-aut-mei=Ikumi
kn-aut-name=•l–ìˆè”ü
kn-aut-sei=•l–ì
kn-aut-mei=ˆè”ü
aut-affil-num=1
ORCID=

en-aut-name=MatsumotoYusuke
en-aut-sei=Matsumoto
en-aut-mei=Yusuke
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kn-aut-mei=—S‰î
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en-aut-name=EndoYoshikatsu
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kn-aut-mei=–F�Ž
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ORCID=

en-aut-name=WatanabeNaoki
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en-aut-mei=Naoki
kn-aut-name=“nç²’¼Ž÷
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kn-aut-mei=’¼Ž÷
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ORCID=

en-aut-name=KaiKyouhei
en-aut-sei=Kai
en-aut-mei=Kyouhei
kn-aut-name=�b”㋱•½
kn-aut-sei=�b”ã
kn-aut-mei=‹±•½
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en-aut-name=SatoShizou
en-aut-sei=Sato
en-aut-mei=Shizou
kn-aut-name=�²“¡ŽlŽO
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kn-aut-mei=ŽlŽO
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en-aut-name=WaniYoji
en-aut-sei=Wani
en-aut-mei=Yoji
kn-aut-name=˜a�m—mŽ¡
kn-aut-sei=˜a�m
kn-aut-mei=—mŽ¡
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=•P˜H�Ô�\Žš•a‰@�@ŠO‰È

affil-num=2
en-affil=
kn-affil=•P˜H�Ô�\Žš•a‰@�@ŠO‰È

affil-num=3
en-affil=
kn-affil=•P˜H�Ô�\Žš•a‰@�@ŠO‰È

affil-num=4
en-affil=
kn-affil=•P˜H�Ô�\Žš•a‰@�@ŠO‰È

affil-num=5
en-affil=
kn-affil=•P˜H�Ô�\Žš•a‰@�@ŠO‰È

affil-num=6
en-affil=
kn-affil=•P˜H�Ô�\Žš•a‰@�@ŠO‰È

affil-num=7
en-affil=
kn-affil=•P˜H�Ô�\Žš•a‰@�@•a—��f’f‰È
en-keyword=Œ´”­�«�\“ñŽw’°Šà�iprimary duodenal cancer�j
kn-keyword=Œ´”­�«�\“ñŽw’°Šà�iprimary duodenal cancer�j
en-keyword=”S‰tŠà�imucinous carcinoma�j
kn-keyword=”S‰tŠà�imucinous carcinoma�j
en-keyword=äX“ª�\“ñŽw’°�Ø�œ�ipancreatoduodenectomy�j
kn-keyword=äX“ª�\“ñŽw’°�Ø�œ�ipancreatoduodenectomy�j
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150930
dt-online=
en-article=
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kn-subject=
en-title=—‘‘ƒŽq‹{“à–Œ�Ç‚Æ�ã”ç�«—‘‘ƒŽîᇂ̑g�DŠw“IƒTƒuƒ^ƒCƒv‚É‚¨‚¯‚éCA19 -9‚Æ CA125‚Ì”½‰ž�«
kn-title=Reactivity of CA19-9 and CA125 in Histological Subtypes of Epithelial Ovarian Tumors and Ovarian Endometriosis
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
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en-aut-name=NakagawaNaohisa
en-aut-sei=Nakagawa
en-aut-mei=Naohisa
kn-aut-name=’†�ì�®‹v
kn-aut-sei=’†�ì
kn-aut-mei=�®‹v
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@
END

start-ver=1.4
cd-journal=joma
no-vol=47
cd-vols=
no-issue=1
article-no=
start-page=31
end-page=43
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150702
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The Development of Studies for Accounting Anomalies and Market Efficiency
kn-title=‰ïŒvƒAƒmƒ}ƒŠ�[Œ¤‹†‚Ì�i“W‚ÆŽs�ê‚ÌŒø—¦�«
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kn-subtitle=
en-abstract=
kn-abstract=
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kn-copyright=

en-aut-name=NakagawaToyotaka
en-aut-sei=Nakagawa
en-aut-mei=Toyotaka
kn-aut-name=’†�ì–L—²
kn-aut-sei=’†�ì
kn-aut-mei=–L—²
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw
END

start-ver=1.4
cd-journal=joma
no-vol=127
cd-vols=
no-issue=1
article-no=
start-page=25
end-page=29
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Laparoscopic total colectomy with lymph node dissection for familial adenomatous polyposis with multiple colorectal cancers
kn-title=‰Æ‘°�«‘å’°‘BŽî�Ç�iFAP�j‚É�‡•¹‚µ‚½“¯Žž�«‚T‘½”­‘å’°Šà‚ɑ΂µ‚ăŠƒ“ƒp�ߊs�´‚𔺂¤• �o‹¾‰º‘å’°‘S“E�p‚ðŽ{�s‚µ‚½‚P—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=�@A 49-year-old Japanese man visited our hospital with chief complaints of difficulty with and bleeding during defecation. After a detailed examination, he was diagnosed with familial adenomatous polyposis (FAP) with multiple (five) colorectal cancers. The tumors were located in the right-sided, left-sided, and sigmoid colon, and the lower rectum. Regional lymph node involvement was observed, but no metastasis to other organs was detected. We, therefore, performed a laparoscopic total colectomy with superior mesenteric artery (SMA) and inferior mesenteric artery (IMA) lymph node dissection. We were able to perform minimally invasive and cosmetically acceptable surgery using laparoscopy instead of highly-invasive open abdominal surgery. Our search of the literature revealed no reported cases of laparoscopic total colectomy with lymph node dissection for FAP with multiple colorectal cancers, making the present case the first to be reported in the literature.
en-copyright=
kn-copyright=

en-aut-name=KatoHiroshi
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ORCID=

en-aut-name=OishiMasahiro
en-aut-sei=Oishi
en-aut-mei=Masahiro
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ORCID=

en-aut-name=KoderaMasahito
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kn-aut-name=�¬Ž›�³�l
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kn-aut-mei=�³�l
aut-affil-num=3
ORCID=

en-aut-name=YamamuraMasao
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en-aut-mei=Masao
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ORCID=

en-aut-name=IkedaHideaki
en-aut-sei=Ikeda
en-aut-mei=Hideaki
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kn-aut-mei=�G–¾
aut-affil-num=5
ORCID=

en-aut-name=MizunoKenji
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en-aut-mei=Kenji
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aut-affil-num=6
ORCID=

en-aut-name=YamashitaYutaka
en-aut-sei=Yamashita
en-aut-mei=Yutaka
kn-aut-name=ŽR‰º—T
kn-aut-sei=ŽR‰º
kn-aut-mei=—T
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=’¹ŽæŽs—§•a‰@�@ŠO‰È

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en-title=Curriculum Vitae of Emeritus Professor Kyojiro NAKAGAWA
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en-title=Ecological studies on water nutsedge (Cyperus serotinus Rottb.) III. The intraspecific variations
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en-title=Ecological studies on water nutsedge (Cyperus serotinus Rottb.) II. The methods of cultural control
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en-title=Ecological studies on water nutsedge (Cyperus serotinus Rottb.) I. Individual ecological characteristics
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en-title=The distribution of tall goldenrod (Solidago altissima L.) in Japan
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en-title=Lung cancer and molecular targeted drugs
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en-aut-name=KiuraKatsuyuki
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en-aut-name=TanimotoMitsune
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affil-num=1
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affil-num=2
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en-keyword=•ªŽq•W“I–ò
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en-keyword=EGFRˆâ“`Žq•ÏˆÙ
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start-ver=1.4
cd-journal=joma
no-vol=125
cd-vols=
no-issue=1
article-no=
start-page=35
end-page=39
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20130401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An epidemiologically rare case of Vibrio vulnificus infection that occurred in October in an inland city of Japan
kn-title=“à—¤’n’ÃŽR‚Å”­�Ç‚µ‚½‹G�ߊO‚ê‚ÌVibrio vulnificusŠ´�õ�Ç
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=�@A 68-year-old man with alcohol addiction, who lived in the suburbs of Tsuyama, an inland city located in northeast Okayama prefecture, was transported to the emergency unit of the Tsuyama Central Hospital in a state of cardiopulmonary arrest (CPA). Despite rigorous systemic investigation and treatment, the patient died 2 hours after arrival. After his death, Vibrio vulnificus was isolated from his blood culture.
�@Vibrio vulnificus causes fatal infection in humans, usually only in areas located close to the sea where appropriate temperature and suitable salt concentration for its growth are available. Therefore, its occurrence is epidemiologically restricted ; in Japan, the western coastal areas, especially in summers, are reported to be the high-risk regions. This is a rare case because it occurred in a city approximately 50 kilometers from both the Sea of Japan and the Pacific coast of Okayama, and at the end of October in 2011. Economic development and distribution systems have made it possible to transport various food products from coastal areas or abroad to any place in a short time, such that these infections can potentially develop in areas other than expected. We should be aware of the increasing risk of Vibrio vulnificus infection during any season and at any place, especially in patients with abnormal liver function.
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en-aut-name=HagiyaHideharu
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en-aut-name=MorimotoNaoki
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affil-num=3
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affil-num=4
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affil-num=5
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kn-affil=’ÃŽR’†‰›•a‰@�@‹~–½‹~‹}ƒZƒ“ƒ^�[

affil-num=6
en-affil=
kn-affil=’ÃŽR’†‰›•a‰@�@‹~–½‹~‹}ƒZƒ“ƒ^�[

affil-num=7
en-affil=
kn-affil=’ÃŽR’†‰›•a‰@�@‹~–½‹~‹}ƒZƒ“ƒ^�[

affil-num=8
en-affil=
kn-affil=’ÃŽR’†‰›•a‰@�@‹~–½‹~‹}ƒZƒ“ƒ^�[

affil-num=9
en-affil=
kn-affil=’ÃŽR’†‰›•a‰@�@‹~–½‹~‹}ƒZƒ“ƒ^�[

affil-num=10
en-affil=
kn-affil=’ÃŽR’†‰›•a‰@�@‹~–½‹~‹}ƒZƒ“ƒ^�[

affil-num=11
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kn-affil=’ÃŽR’†‰›•a‰@�@‹~–½‹~‹}ƒZƒ“ƒ^�[
en-keyword=Vibrio vulnificus
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END

start-ver=1.4
cd-journal=joma
no-vol=124
cd-vols=
no-issue=3
article-no=
start-page=243
end-page=247
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20121203
dt-online=
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en-title=A case of intracystic carcinoma of the breast showing pathological complete response by neoadjuvant chemotherapy
kn-title=�p‘O‰»Šw—Ö@‚É‚æ‚è•Ç‚ªäÉ”–‰»‚µ‘g�DŠw“IŠ°‰ð�ipCR�j‚Æ‚È‚Á‚½‹�‘å”X–E“à“ûŠà‚Ì‚P—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=�@A 31-year-old woman presented to our hospital because of a lump 5cm in diameter in her right breast. Ultrasonography revealed a multilocular cystic mass with partial thickening of the wall and the septum. Core needle biopsy (CNB) of the septum confirmed invasive ductal carcinoma. The patient was administered neoadjuvant chemotherapy consisting of 12 cycles of weekly paclitaxel followed by 4 cycles of FEC (5FU, Epilubicin and cyclophosphamide). While the thickness of the wall and septum became thinner, the tumor size did not change in diameter. She underwent right mastectomy and sentinel node biopsy. Post-surgical histopathological findings showed a pathological complete response (pCR).<br>
�@We report a rare case of invasive ductal carcinoma presenting a multilobular phenotype which showed pCR by neoadjuvant chemotherapy despite no size reduction of the tumor.
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en-aut-name=MatsuokaJunji
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en-aut-name=MotokiTakayuki
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en-aut-name=IwamotoTakayuki
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en-aut-name=MakabeMikio
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en-aut-name=NogamiHiromi
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affil-num=1
en-affil=
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affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»ŠíŠO‰ÈŠw

affil-num=3
en-affil=
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affil-num=4
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kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»ŠíŠO‰ÈŠw

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠw•a‰@�@•a—��f’f‰È

affil-num=6
en-affil=
kn-affil=‰ªŽR‘å•ŸƒNƒŠƒjƒbƒN

affil-num=7
en-affil=
kn-affil=‰ªŽR‘å•ŸƒNƒŠƒjƒbƒN

affil-num=8
en-affil=
kn-affil=‰ªŽR‘å•ŸƒNƒŠƒjƒbƒN

affil-num=9
en-affil=
kn-affil=‰ªŽR’†‰›•a‰@

affil-num=10
en-affil=
kn-affil=–ì�ã•a‰@
en-keyword=”X–E“à“ûŠà�iintracystic breast cancer�j
kn-keyword=”X–E“à“ûŠà�iintracystic breast cancer�j
en-keyword=�p‘O‰»Šw—Ö@�ineoadjuvant chemotherapy�j
kn-keyword=�p‘O‰»Šw—Ö@�ineoadjuvant chemotherapy�j
en-keyword=‘g�DŠw“IŠ®‘S‘tŒ÷�ipahthological CR�j
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start-ver=1.4
cd-journal=joma
no-vol=57
cd-vols=
no-issue=4
article-no=
start-page=241
end-page=251
dt-received=
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dt-accepted=
dt-pub-year=2008
dt-pub=20080425
dt-online=
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en-subject=
kn-subject=
en-title=Basic Study on Activation of Antioxidation Function in Some Organs of Mice by Radon Inhalation Using New Radon Exposure Device
kn-title=ƒ‰ƒhƒ“‹z“üŽŽ�ì‘•’u‚É‚æ‚éƒ}ƒEƒX�”‘ŸŠí’†‚Ì�RŽ_‰»‹@”\‚̘´�i‚ÉŠÖ‚·‚錤‹†
en-subtitle=
kn-subtitle=
en-abstract=There are a lot of life style diseases that are related to reactive oxygen species in indications of the radon therapy, and, the further clarification of mechanism is expected. Therefore, in this study, we investigated the activation of antioxidation function in some organs of mice by radon inhalation using the new radon exposure device. It was enable that this device was the adjustments of radon concentration by changing the air flow rate to the specially processed radon source and so on. The mice were made to inhale the radon of 400Bq/m<sup>3</sup> or 4000Bq/m<sup>3</sup> with this device. Results show that in brain, lungs, liver, and kidney, both the activities of superoxide dismutase(SOD) and catalase increased, and lipid peroxide levels decreased. This suggests that radon inhalation enhanced the antioxidation function. These findings are important in understanding the mechanism of diseases in which radon therapy is used as treatment, and most of which are called activated oxygen-related diseases.
kn-abstract=ƒ‰ƒhƒ“—Ö@‚Ì“K‰ž�Ç‚É‚ÍŠˆ�«Ž_‘f‚É—R—ˆ‚·‚é�¶Šˆ�KŠµ•a‚ª‘½‚­�C‚»‚Ì‹@�\‚Ì�X‚È‚é‰ð–¾‚ªŠú‘Ò‚³‚ê‚Ä‚¢‚é�B‚Ü‚½�C”Ä—p�«‚ª‚ ‚èˆãŠw“IŒø‰Ê‚ª�ÄŒ»‚Å‚«‚郉ƒhƒ“‹z“ü‘•’u‚Ì�\’z‚͈Ӌ`‚ª‘å‚«‚¢�B‚±‚Ì‚½‚ß�C’˜ŽÒ‚ç‚Í‹¤“¯‚ÅŠJ”­‚µ‚½ƒ‰ƒhƒ“‹z“üŽŽ�ì‘•’u‚ð—p‚¢�Cƒ}ƒEƒX�”‘ŸŠí’†‚Ì�RŽ_‰»‹@”\‚̕ω»“Á�«‚ðŒŸ“¢‚µ‚½�Bƒ‰ƒhƒ“‹z“üŽŽ�ì‘•’u‚Í�C“ÁŽê‰Á�H‚µ‚½ƒ‰ƒhƒ“�üŒ¹‚ðŽû”[‚µ‚½ƒ†ƒjƒbƒg‚Ì�”—Ê�C‚»‚ê‚Ö‚Ì‘—•——Ê‹y‚ÑŽ¼“x‚È‚Ç‚ð’²�ß‚·‚邱‚Æ‚É‚æ‚胉ƒhƒ“”Z“x‚ðŽ©�Ý‚É’²�®‰Â”\‚É‚·‚é‚à‚Ì‚Å‚ ‚é�B‚±‚Ì‘•’u‚É‚æ‚èƒ}ƒEƒX‚É400Bq/m<sup>3</sup>‚ ‚é‚¢‚Í4000Bq/m<sup>3</sup>‚̃‰ƒhƒ“‚ð‹z“ü‚³‚¹‚½�B‚»‚ÌŒ‹‰Ê�C”]�E”x�EŠÌ‘Ÿ�E�t‘Ÿ‚É‚¨‚¢‚Ä�C�RŽ_‰»Œn�y‘f‚Å‚ ‚éSOD‚ƃJƒ^ƒ‰�[ƒ[‚Ì—¼Šˆ�«‚ª‘�‰Á‚µ�C‰ßŽ_‰»Ž‰Ž¿—Ê‚ªŒ¸�­‚µ‚½�B‚±‚Ì�RŽ_‰»‹@”\‚̘´�i‚É‚æ‚è�C–{ŽÀŒ±�ðŒ�‚ł̃‰ƒhƒ“‹z“ü‚ÍŠˆ�«Ž_‘f�áŠQ‚Ì—}�§�C‚·‚È‚í‚¿�C�¶Šˆ�KŠµ•a‚Ì—\–h‚â�Ç�óŠÉ˜a‚ÉŒø‰Ê‚Ì‚ ‚é‰Â”\�«‚ª‰ü‚ß‚ÄŽ¦�´‚Å‚«‚½�B
en-copyright=
kn-copyright=

en-aut-name=NakagawaShinya
en-aut-sei=Nakagawa
en-aut-mei=Shinya
kn-aut-name=’†�ì�T–ç
kn-aut-sei=’†�ì
kn-aut-mei=�T–ç
aut-affil-num=1
ORCID=

en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=•Ð‰ª—²�_
kn-aut-sei=•Ð‰ª
kn-aut-mei=—²�_
aut-affil-num=2
ORCID=

en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=”—“c�W�O
kn-aut-sei=”—“c
kn-aut-mei=�W�O
aut-affil-num=3
ORCID=

en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=�Î�X—L
kn-aut-sei=��X
kn-aut-mei=—L
aut-affil-num=4
ORCID=

en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=‰ÔŒ³�Ž–¤
kn-aut-sei=‰ÔŒ³
kn-aut-mei=�Ž–¤
aut-affil-num=5
ORCID=

en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=ŽR‰ª�¹“T
kn-aut-sei=ŽR‰ª
kn-aut-mei=�¹“T
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@•ÛŒ’ŠwŒ¤‹†‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@•ÛŒ’ŠwŒ¤‹†‰È

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@•ÛŒ’ŠwŒ¤‹†‰È

affil-num=4
en-affil=
kn-affil=“Æ—§�s�­–@�l�@“ú–{Œ´Žq—ÍŒ¤‹†ŠJ”­‹@�\�lŒ`“»ŠÂ‹«‹Z�pƒZƒ“ƒ^�[

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@•ÛŒ’ŠwŒ¤‹†‰È

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@•ÛŒ’ŠwŒ¤‹†‰È
en-keyword=new radon exposure device
kn-keyword=new radon exposure device
en-keyword=radon inhalation
kn-keyword=radon inhalation
en-keyword=antioxidative function
kn-keyword=antioxidative function
en-keyword=superoxide dismutase
kn-keyword=superoxide dismutase
en-keyword=catalase
kn-keyword=catalase
en-keyword=lipid peroxide
kn-keyword=lipid peroxide
en-keyword=active oxygen
kn-keyword=active oxygen
en-keyword=mouse
kn-keyword=mouse
en-keyword=radon-222
kn-keyword=radon-222
END

start-ver=1.4
cd-journal=joma
no-vol=124
cd-vols=
no-issue=2
article-no=
start-page=149
end-page=153
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of strangulated ileus caused by transomental hernia with reference to previously reported cases
kn-title=�p‘O�f’f‚µ“¾‚½‘å–Ô—ô�Eƒwƒ‹ƒjƒA‚̈ê—á�\–{–M•ñ��203—á‚Ì—Õ�°•a—�Šw“IŒŸ“¢�\
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Transomental hernia often develops into strangulated ileus. We report on an 81-year-old man with strangulated ileus due to transomental hernia, diagnosed preoperatively by abdominal CT. The patient was referred to our surgical division because of progressive abdominal pain and vomiting. He had no history of laparotomy. An abdominal CT scan showed dilated small intestinal loops with intraluminal air and strangulated small intestinal loops with engorged mesenteric vessels. We diagnosed this as a strangulated internal hernia due to transomental hernia and conducted an emergency laparotomy. The jejunum had herniated through an abnormal hiatus of the greater omentum to the peritoneal cavity. The strangulated intestinal loop, about 15 cm long, was released and the postoperative course was uneventful. In the absence of a previous laparotomy, the differential diagnosis of intestinal obstruction should include internal hernia. An abdominal CT scan is useful for the preoperative and prompt diagnosis of transomental hernia.
en-copyright=
kn-copyright=

en-aut-name=KimuraYuji
en-aut-sei=Kimura
en-aut-mei=Yuji
kn-aut-name=–Ø‘º—TŽi
kn-aut-sei=ЯԼ
kn-aut-mei=—TŽi
aut-affil-num=1
ORCID=

en-aut-name=IwakawaKazuhide
en-aut-sei=Iwakawa
en-aut-mei=Kazuhide
kn-aut-name=Šâ�ì˜a�G
kn-aut-sei=Šâ�ì
kn-aut-mei=˜a�G
aut-affil-num=2
ORCID=

en-aut-name=NishieManabu
en-aut-sei=Nishie
en-aut-mei=Manabu
kn-aut-name=�¼�]Šw
kn-aut-sei=�¼�]
kn-aut-mei=Šw
aut-affil-num=3
ORCID=

en-aut-name=InagakiMasaru
en-aut-sei=Inagaki
en-aut-mei=Masaru
kn-aut-name=ˆîŠ_—D
kn-aut-sei=ˆîŠ_
kn-aut-mei=—D
aut-affil-num=4
ORCID=

en-aut-name=IwagakiHiromi
en-aut-sei=Iwagaki
en-aut-mei=Hiromi
kn-aut-name=ŠâŠ_”Ž–¤
kn-aut-sei=ŠâŠ_
kn-aut-mei=”Ž–¤
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=2
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=3
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=4
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=5
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È
en-keyword=‘å–Ô—ô�Eƒwƒ‹ƒjƒA�itransomental hernia�j
kn-keyword=‘å–Ô—ô�Eƒwƒ‹ƒjƒA�itransomental hernia�j
en-keyword=�i�N�«ƒCƒŒƒEƒX�istrangulated ileus�j
kn-keyword=�i�N�«ƒCƒŒƒEƒX�istrangulated ileus�j
END

start-ver=1.4
cd-journal=joma
no-vol=28
cd-vols=
no-issue=
article-no=
start-page=59
end-page=62
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=201204
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Usefulness of ICR mice as genetic resources
kn-title=ICRƒ}ƒEƒX‚̈â“`ŽqŽ‘Œ¹‚Æ‚µ‚Ä‚Ì—L—p�«
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=ICR(Yok:ICR)mice were introduced into the National Instltute of Infectious Diseases in 1965,and have been bred and produced there.Two inbred mutant mouse strains,MPS and ICGN,were created using(originated from)Yok:ICR mice in 1986.The MPS and ICGN mouse strains have served as the
animal disease models of mycoplasma infectious disease and congenital nephritic syndrome,respectively.
Genetic variations were detected by the genetic monitoring of Yok:ICR mice using biochemical markers.However, no difference was detected in gene expression profiles between the MPS and ICGN mouse strains.ICR mice may harbor genes that are spontaneously mutated,thereby allowing the creation of
new pathological models through the segregation and/or selection(screening)of mutant genes.
en-copyright=
kn-copyright=

en-aut-name=YamamotoYoshie
en-aut-sei=Yamamoto
en-aut-mei=Yoshie
kn-aut-name=ŽR–{”ü�]
kn-aut-sei=ŽR–{
kn-aut-mei=”ü�]
aut-affil-num=1
ORCID=

en-aut-name=Uchio-YamadaKozue
en-aut-sei=Uchio-Yamada
en-aut-mei=Kozue
kn-aut-name=“à”ö-ŽR“c‚±‚¸‚¦
kn-aut-sei=“à”ö-ŽR“c
kn-aut-mei=‚±‚¸‚¦
aut-affil-num=2
ORCID=

en-aut-name=TakanoKaoru
en-aut-sei=Takano
en-aut-mei=Kaoru
kn-aut-name=�‚–ìŒO
kn-aut-sei=�‚–ì
kn-aut-mei=ŒO
aut-affil-num=3
ORCID=

en-aut-name=OguraAtsuo
en-aut-sei=Ogura
en-aut-mei=Atsuo
kn-aut-name=�¬‘q�~˜Y
kn-aut-sei=�¬‘q
kn-aut-mei=�~˜Y
aut-affil-num=4
ORCID=

en-aut-name=AsanoToshihiko
en-aut-sei=Asano
en-aut-mei=Toshihiko
kn-aut-name=�ó–ì•q•F
kn-aut-sei=�ó–ì
kn-aut-mei=•q•F
aut-affil-num=5
ORCID=

en-aut-name=NakagawaMasarou
en-aut-sei=Nakagawa
en-aut-mei=Masarou
kn-aut-name=’†�ì‰ë˜Y
kn-aut-sei=’†�ì
kn-aut-mei=‰ë˜Y
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=�‘—§Š´�õ�ÇŒ¤‹†�Š

affil-num=2
en-affil=
kn-affil=ˆã–òŠî”ÕŒ¤‹†�Š

affil-num=3
en-affil=
kn-affil=ˆã–òŠî”ÕŒ¤‹†�Š

affil-num=4
en-affil=
kn-affil=—�‰»ŠwŒ¤‹†�Š

affil-num=5
en-affil=
kn-affil=�‘—§Š´�õ�ÇŒ¤‹†�Š

affil-num=6
en-affil=
kn-affil=�‘—§Š´�õ�ÇŒ¤‹†�Š
END

start-ver=1.4
cd-journal=joma
no-vol=124
cd-vols=
no-issue=1
article-no=
start-page=63
end-page=66
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Pathological complete response of advanced gastric cancer with pyloric stenosis to neoadjuvant S-1/CDDP chemotherapy: A case report
kn-title=S-1/CDDP�p‘O‰»Šw—Ö@‚É‚æ‚è‘g�DŠw“ICR‚ª“¾‚ç‚ꂽ—H–å‹·�ó�‡•¹�i�sˆÝŠà‚Ì‚P—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 59-year-old man with epigastric discomfort and anorexia was referred to our hospital. Endoscopy revealed a type 3 advanced gastric cancer with pyloric stenosis diagnosed as a poorly differentiated adenocarcinoma in the biopsy specimens. A gastrojejunal bypass operation was performed because of direct invasion to the pancreas. The patient was treated by three courses of neoadjuvant chemotherapy with S-1/CDDP. Follow-up abdominal CT scan revealed that the primary tumor had become smaller, suggesting that a partial response had been achieved. Distal gastrectomy with D2 lymphadenectomy was performed. The histopathological examination showed no residual cancer cells in the primary lesion or dissected lymph nodes. Final chemotherapy efficacy was evaluated as Grade 3. The patient was treated with S-1 for one year after the gastrectomy and lymphadenectomy and has been followed up for 18 months without evidence of recurrence.
en-copyright=
kn-copyright=

en-aut-name=NishizakiMasahiko
en-aut-sei=Nishizaki
en-aut-mei=Masahiko
kn-aut-name=�¼�è�³•F
kn-aut-sei=�¼�è
kn-aut-mei=�³•F
aut-affil-num=1
ORCID=

en-aut-name=FujiwaraYasuhiro
en-aut-sei=Fujiwara
en-aut-mei=Yasuhiro
kn-aut-name=“¡Œ´�N�G
kn-aut-sei=“¡Œ´
kn-aut-mei=�N�G
aut-affil-num=2
ORCID=

en-aut-name=ChoudaYasuhiro
en-aut-sei=Chouda
en-aut-mei=Yasuhiro
kn-aut-name=’š“c‘×�G
kn-aut-sei=’š“c
kn-aut-mei=‘×�G
aut-affil-num=3
ORCID=

en-aut-name=KanazawaTakashi
en-aut-sei=Kanazawa
en-aut-mei=Takashi
kn-aut-name=‹ààV‘ì
kn-aut-sei=‹ààV
kn-aut-mei=‘ì
aut-affil-num=4
ORCID=

en-aut-name=NinomiyaMotoki
en-aut-sei=Ninomiya
en-aut-mei=Motoki
kn-aut-name=“ñ‹{ŠîŽ÷
kn-aut-sei=“ñ‹{
kn-aut-mei=ŠîŽ÷
aut-affil-num=5
ORCID=

en-aut-name=FujiwaraToshiyoshi
en-aut-sei=Fujiwara
en-aut-mei=Toshiyoshi
kn-aut-name=“¡Œ´�r‹`
kn-aut-sei=“¡Œ´
kn-aut-mei=�r‹`
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»ŠíŠO‰ÈŠw

affil-num=2
en-affil=
kn-affil=�L“‡Žs—§�L“‡Žs–¯•a‰@�@ŠO‰È

affil-num=3
en-affil=
kn-affil=�L“‡Žs—§�L“‡Žs–¯•a‰@�@ŠO‰È

affil-num=4
en-affil=
kn-affil=�L“‡Žs—§�L“‡Žs–¯•a‰@�@ŠO‰È

affil-num=5
en-affil=
kn-affil=�L“‡Žs—§�L“‡Žs–¯•a‰@�@ŠO‰È

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»ŠíŠO‰ÈŠw
en-keyword=—H–å‹·�ó (pyloric stenosis)
kn-keyword=—H–å‹·�ó (pyloric stenosis)
en-keyword=�i�sˆÝŠà (advanced gastric cancer)
kn-keyword=�i�sˆÝŠà (advanced gastric cancer)
en-keyword=S-1/CDDP
kn-keyword=S-1/CDDP
en-keyword=�p‘O‰»Šw—Ö@ (neoadjuvant chemotherapy)
kn-keyword=�p‘O‰»Šw—Ö@ (neoadjuvant chemotherapy)
en-keyword=‘g�DŠw“ICR (pathological CR)
kn-keyword=‘g�DŠw“ICR (pathological CR)
END

start-ver=1.4
cd-journal=joma
no-vol=33
cd-vols=
no-issue=383
article-no=
start-page=853
end-page=855
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1921
dt-pub=19211231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=œ¦�«–¬—�–Œ�ã”çŽîƒm‹}‘¬çzˆÚƒmˆê—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=’†�ì•�—Y
kn-aut-sei=’†�ì
kn-aut-mei=•�—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΛ{�ê–å›{�ZŽY•w�l‰È
END

start-ver=1.4
cd-journal=joma
no-vol=33
cd-vols=
no-issue=373
article-no=
start-page=127
end-page=158
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1921
dt-pub=19210228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=ƒo�[ƒ“ƒXŽ��uƒ\ƒŠƒEƒ€�v‰tƒjˆËƒ‹�uƒsƒGƒ�ƒOƒ‰ƒtƒB�[�vƒj�Aƒe
en-subtitle=
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kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=’†�ì�¬Žl˜Y
kn-aut-sei=’†�ì
kn-aut-mei=�¬Žl˜Y
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=‘º�¼“ÄŽ¡
kn-aut-sei=‘º�¼
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aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΛ{�ê–å›{�Z”ç‰Ô”å”A‰È‹y�uƒŒƒ“ƒgƒQƒ“�v‰È

affil-num=2
en-affil=
kn-affil=‰ªŽRçΛ{�ê–å›{�Z”ç‰Ô”å”A‰È‹y�uƒŒƒ“ƒgƒQƒ“�v‰È
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110930
dt-online=
en-article=
kn-article=
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kn-subject=
en-title=ƒjƒtƒFƒJƒ‰ƒ“ƒg’ï�R�«•s�®–¬‚ɑ΂·‚é�Ã’�ƒAƒ~ƒIƒ_ƒ�ƒ““Š—^‚ɂ‚¢‚Ä�\�d�Ç�S•s‘SŠ³ŽÒ˜A‘±11—á‚Å‚ÌŒŸ“¢�\
kn-title=Use of Intravenous Amiodarone in the Treatment of Nifekalant-Resistant Arrhythmia : A Review of 11 Consecutive Cases with Severe Heart Failure
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaKoji
en-aut-sei=Nakagawa
en-aut-mei=Koji
kn-aut-name=’†�ì�WŽu
kn-aut-sei=’†�ì
kn-aut-mei=�WŽu
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw
END

start-ver=1.4
cd-journal=joma
no-vol=123
cd-vols=
no-issue=2
article-no=
start-page=129
end-page=132
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Laparoscopic surgery for mesenteric Castleman's disease
kn-title=• �o‹¾‰º‚É“E�o‚µ‚¦‚½�ã�sŒ‹’°ŠÔ–Œ”­�¶‚ÌCastleman•a‚Ì‚P—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We report herein a case of mesenteric Castleman's disease which was confirmed on pathology. A 60-year-old man was admitted to our hospital complaining of abdominal pain. On the physical examination, there was no palpable mass. Computed tomography findings and magnetic resonance imaging revealed a well circumscribed, lobulated round mass on the right side of the superior mesenteric vein. Laparoscopic surgery for the mesenteric tumor was carried out to obtain a definite diagnosis and treatment. In the operative field, the mass was located on the ascending colic mesentery and measured about 3 cm in size. It was solid and surrounded by a thin fibrous capsule. The histological diagnosis of the mesenteric tumor was hyaline vascular type Castleman's disease. The postoperative course of the patient was uneventful, and he was discharged on the 10th postoperative day.
en-copyright=
kn-copyright=

en-aut-name=NishieManabu
en-aut-sei=Nishie
en-aut-mei=Manabu
kn-aut-name=�¼�]Šw
kn-aut-sei=�¼�]
kn-aut-mei=Šw
aut-affil-num=1
ORCID=

en-aut-name=OtsukaShinya
en-aut-sei=Otsuka
en-aut-mei=Shinya
kn-aut-name=‘å’Ë�^�Æ
kn-aut-sei=‘å’Ë
kn-aut-mei=�^�Æ
aut-affil-num=2
ORCID=

en-aut-name=TomodaJun
en-aut-sei=Tomoda
en-aut-mei=Jun
kn-aut-name=—F“c�ƒ
kn-aut-sei=—F“c
kn-aut-mei=�ƒ
aut-affil-num=3
ORCID=

en-aut-name=FujiwaraKeishi
en-aut-sei=Fujiwara
en-aut-mei=Keishi
kn-aut-name=“¡Œ´ŒhŽm
kn-aut-sei=“¡Œ´
kn-aut-mei=ŒhŽm
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=2
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=3
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@“à‰È

affil-num=4
en-affil=
kn-affil=Œõ�¶•a‰@�@“à‰È
en-keyword=Œ‹’°ŠÔ–Œ (mesocolon)
kn-keyword=Œ‹’°ŠÔ–Œ (mesocolon)
en-keyword=Castleman•a (Castleman's disease)
kn-keyword=Castleman•a (Castleman's disease)
en-keyword=• �o‹¾Žè�p (laparoscopic surgery)
kn-keyword=• �o‹¾Žè�p (laparoscopic surgery)
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=6
article-no=
start-page=1193
end-page=1205
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=?ber die Wirkung der reinen Lipage auf Blutbefunde
kn-title=�uƒŠƒp�[ƒ[�vƒmŒŒ‰t�ŠŒ©ƒj‹yƒ{ƒX‰e‹¿
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Nach dem Yerfahren von Willst?tter und Waldschmidt-Leitz hat der Verf. aus dem Pankreas von Schweinen Lipasel?sung hergestellt, indem er zun?chst das Pankreas durch Anwendung von Azeton und ?ther getrocknet, durch Glyzerin extrahiert, nach Ans?tuerung die Lipase an Tonerde-B adsorbieren liess und schliesslich mittels einer L?sung von Ammonphosphatglyzerin extrahiert hatte. Die auf diese Weise erhaltene Lipasel?sung hat er sodann den Versuchskaninchen intraven?s eingef?hrt, um die Zahl der Leukozyten, Erythrozyten und Blutpl?ttchen, Blutsenkungsgeschwindigkeit, Blutungs-und gerinnungszeit festzugtellen.Als Kontrolle dienten die Kaninchen, denen die L?sung von Ammonphosphatglyzerin intraven?s eingef?hrt worden war. Ausserdem hat der Verf. anderen Kaninchen vegetative Rizinuslipase intrapelitoneal injiziert und gleiche Bestimmungen vorgenommen. Aus diesen Versuchen erhielt der Verf.folgende Ergebnisse: 1) Die Leukozyten scheinen quantitativ zuzunehmen. 2) Die Erythrozyten nehmen im allgemeinen an Mengeg ab, ab, aber nach intraperitonealer Einf?hrungmng der Rizinuslipase tritt bei ihnen vielmehr Vermehrung ein. 3) Die Senkungsgeschwindigkeit der Erythrozyten wird zwar beschleunigt, aber in nur versch windend geringem Masse. 4) Blutungs- und Gerinnungszeit wird ohne allen Zweifel vel?ngertb. 5) Die Blutpl?ttchen nehmen auch an Zahl ab.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshio
en-aut-sei=Nakagawa
en-aut-mei=Yoshio
kn-aut-name=’†�ì”ü—Y
kn-aut-sei=’†�ì
kn-aut-mei=”ü—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{’ÓcŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=6
article-no=
start-page=1179
end-page=1192
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Untersuchungen der Lipase und der Toxizitat des Pankreas bei der experimentell hervorgerufenen akuten Pankreasnekrose (VI. Mitteilung). ?ber die Giftigkeit des Pankreas bei experimcntell hervorgerufener akuter Pankreasnekrose
kn-title=›‰é„“I‹}�«äX‘ŸšÓŽ€Žžƒj‰—ƒPƒ‹�uƒŠƒp�[ƒ[�vâ�ƒj“Å�«ƒjè�ƒXƒ‹Œ¤‹†�i‘æ4•Ò�j›‰é„“I‹}�«äX‘ŸšÓŽ€Žžƒj‰—ƒPƒ‹äX‘Ÿƒm“Å�«ƒjè�ƒXƒ‹Œ¤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Es ist bereits von vielen Autoren festgestellt worden, dass bei t?dlicher Nekrose der Bauchspeicheldr?se die Spaltungsprodukte von Eiweiss eine wichtige Rolle spielen. Um diese Verh?ltnisse noch h?her zu er?rtern, hat der Verf. 50%ige Emulsion von Hundpankreas in die Schwanzvenen von M?usen eingef?hrt und fand, dass zwischen dem normalen und dem nekrotischen Pankreas an Toxizit?t kein erheblicher Unterschied vorhanden war. Beim Kochen der Emulsion auf 10'-30' aber gingen die Fermente des Pankreas fast vollstandig verloren und es ergab sich, dass in diesen Fall das durch Einf?hrung von Oliven?l nekrotisierte Pankreas die st?rkste Giftigkeit hervorbrachte. Als er ferner gesundes und nekrotisiertes Pankreas von Hunden nach Goodpasture und Clark auf autolytischem Wege verfl?ssigte und sodann das anges?uerte Filtrat durch Hinzuf?gung von Eisessig zum Fall brachte, konnte er zwischen den beiden Niederschl?gen keinen grossen Unterschied an Giftigkeit feststellen. Das Kommt nach dem Erachten des Verf.s daher, dass beim gesunden Pankreas durch Autolyse giftige Substanzen in reichlicher Menge entstehen. Wenn man aber das Pankreas ohne Ausf?hrung der Autolyse emulgierte und das sauer reagierende Filtrat sofort durch Eisessig zum Fall brachte, ergab sich, dass das in st?rkerem Masse nekrotisierte Pankreas viel betr?chtlichere Giftigkeit aufwies als das nicht so stark krankhaft ver?nderte Pankreas. Um den Einfluss der Autolyse auf die Giftigkeit festzustellen, liess der Verf. das Pankreas nach der Einf?brung von Galle, ?lusw. 24-48 Stunden lang der Autolyse verfallen. Daraus stellte sich heraus, dass die Giftigkeit um so st?rker auftrat, je l?nger das Pankreas auf der Autolyse verlassen worden waren. Um schliesslich das Wesen dieser giftigen Substanzen festzustellen, hat der Verf. bei der Pankreasemulsion die Phosphorwolframs?ure-Isolierung durchgef?hrt und fand, dass der basische R?ckstand viel st?rkere Giftigkeit aufwies als das saure Filtrat.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshio
en-aut-sei=Nakagawa
en-aut-mei=Yoshio
kn-aut-name=’†�ì”ü—Y
kn-aut-sei=’†�ì
kn-aut-mei=”ü—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{’ÓcŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=5
article-no=
start-page=1147
end-page=1158
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Ein Fall von traumatischer Pankreasnekrose
kn-title=ŠO���«äXäf‰óŽ€ƒm1—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) Der Verf. konnte bei einem 33 j?hrigen Mann, der infolge von stumpfer Gewalteinwirkung auf den Oberbauch akute Pankreasnekrose erlitt, bald nach dem Auftritt diesen Krankheit (1 Stunde 50 Minuten sp?ter) die Operation ausf?hren und den Kranken zur Heilung bringen. 2) Es handelte sich um eine ausgedehnte Blutung am Kopf- und K?rperteile des Pankreas ohne Sch?digungen anderer Organe der B?uchh?hle. Gesunder Herd wurde nur am Schwanzteil des Pankreas beobachtet, 3) Der Kranke wurde n?chtern verwundet, was die Annahme nahe legte, dass sich das Pankreas, vom topographisch-anatomischen Standpunkt aus betrachtet, in einer leicht zu verletzenden l. age befand. An Hand von Statistiken weist der Verf. darauf hin, dass bei jugendlichen Personen die Verletzung des Pankreas auch nach Mahlzeit leicht zustande kommt. 4) Allgemeines Symptom bestand in traumatischer Schock. Als lokale Symptome zeigte der Oberbauch grosse Schmerzhaftigkeit gegen die r-Oberbauchgegend hin. Der Muskel dieser Gegend befand sich im Zustand der sog. D?fense musculaire. Vor der Operation wurden eine Vermehrung der weissen Zellen sowie eine leichtgradige Linksverschiebung und eine Verringerung der roten Zellen beobachtet. Die Menge der Harndiastase war normal, wahread die der Serum-Diastase eine kleine Vermehrung aufwies, 5) Bei der Operation wurde das Exsudat der Pankreasgegend durch eine Drainage, welche durch das Lig. gastrocolica hindurchgezogen wurde, auf das m?glichste ausgeschieden. Das Exsudat das sich vom Foramen Winslowi her in der Umgebung der Gallenblase stagnierte, wurde durch Anlegung einer Drainage an dieser Gegend abgelassen. 6) Der Verf. sammelte sodann in der japanischen Literatur I8 F?lle der subkutanen Sch?digung des Pankreas, an denen er st?tistische Beobachtung angestellt hat. Daraus stellte sich heraus, dass die Sch?digung meistens durch Stoss Von Holz und Stein, durch Hufschlag, Eingeklemmtwerden zwischen den Pufferapparaten usw. verursacht wurde. Das Alter der Patienten lag zwischen 6 und 40 Jahren. Die Krankheit kamen fast ausschliesslich bei M?nnern vor. Nach Art der Verletzungen nimmt unvollst?ndige Zerreissung die erste Stelle ein, ihr folgen dann Blutung, Vollst?ndige Zerreissung, Quetschung und Quetschungsnekrose. Bez?glich des Ausgangs der Krankheit ergibt sich, dass von den 18 Fallen 13 F?lle zur Heilung kamen, 4 F?lle t?dlich ausgingen and 1 Fall unklar war.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshio
en-aut-sei=Nakagawa
en-aut-mei=Yoshio
kn-aut-name=’†�ì”ü—Y
kn-aut-sei=’†�ì
kn-aut-mei=”ü—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{’ÓcŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=5
article-no=
start-page=1074
end-page=1080
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Untersuchungen der Lipase und der Toxizit?t des Pankreas bei der experimentell hervorgerufenen akuten Pankreasnekrose (III. Mitteilung). ?ber die Menge der Fetts?uren im nekrotischen Pankreas bei experimentell hervorgerufener akuter Pankreasnekrose
kn-title=›‰é„“I‹}�«äXäf‰óŽ€Žžƒj‰—ƒPƒ‹�uƒŠƒp�[ƒ[�vâ�ƒj“Å�«ƒjè�ƒXƒ‹Œ¤‹†�i‘æ3•Ò�j›‰é„“I‹}�«äXäf‰óŽ€Žžƒj‰—ƒPƒ‹‰óŽ€äXäf’†ƒmŽ‰–bŽ_—ʃj�Aƒe
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Es ist schon l?ngst allgemein anerkannt, dass bei akuter Pankreasnekrose die Fette durch Einwirkung von Lipasen in Fetts?uren und Glyzerin abgebaut werden, und dass die Fetts?uren dann mit dem im Blut enthaltenen Kalzium in Verbindung treten, wodurch toxische Seifen entstehen, die das Pankreasgewebe zur Nekrose f?hren. Der Verf. hat bei Versuchshunden durch Einfubr?ng von Galle und Oliven?l oder durch Unterbindung der Arterien des Pankreas usw. akute Paekreasnekrose hervorgerufen. Als er nach dem Tode der Hunden durch Anwepdung der Modifikation der Methode von Bloor, Pelkan und Allen die Menge der Fetts?ueren im Pankreas bestimmt hatte, ergab sich, dass die Fetts?uren des Pankreas bei nekrotjsierten Partien am starksten zunahmen, weniger stark bei Blutungspartien. Bei ?demat?sen Partien wurde bisweilen beobachtet, dass die Fetts?uren eine st?rkere Verminderung als bei der noch gesund gebliebenen Partien zeigten. Das kommt wohl nach dem Erachten des Verf. s daher, dass diese ?demat?sen Partien reichlich Wasser enthielten. Eine besonders starke Vermehrnng der Fetts?uren nach Einfuhrung von Oliven?l findet ihre Erkl?rung in der Spaltung des Oliven?ls. In einem klinischen Fall von akuter Pankreasnekrose konnte der Verf. in dem bei der Sektion herausgenommenen Pankreas eine betr?chtliohe Vermehung der Fests?uren feststellen.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshio
en-aut-sei=Nakagawa
en-aut-mei=Yoshio
kn-aut-name=’†�ì”ü—Y
kn-aut-sei=’†�ì
kn-aut-mei=”ü—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{’ÓcŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=5
article-no=
start-page=1063
end-page=1074
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Unterauchungen der Lipase und der Toxizitat des Pankreae bei der experimentell hervorgerufenen akuten Pankreasnekrose (II. Mitteilung) ?ber die Menge der Lipase in der Lunge, Leber, Milz, den Nieren und dem Pankreas bei experimentell hervorgerufener akuter Pankreasnekrose
kn-title=›‰é„“I‹}�«äX‘Ÿ‰óŽ€Žžƒj‰—ƒPƒ‹�uƒŠƒp�[ƒ[�vâ�ƒj“Å�«ƒjè�ƒXƒ‹Œ¤‹†�i‘æ2•Ò�j›‰é„“I‹}�«äX‘Ÿ‰óŽ€Žžƒj‰—ƒPƒ‹”xŠÌäB�täX‘Ÿ’†ƒm�uƒŠƒy�[ƒ[�v—ʃj�Aƒe
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Um die quantitative Verteilung der Lipase in den wichtigeren Organen des K?rpersbei akuter Pankreasnekrose featzustellen, hat der Verf. bei Versuchshunden akute Pankreasnekrose experimentell hervorgerufen und nach dem Tode bzw. nach kunstlicher T?tung der Hunde die Lunge, Leber, Milz und die Nieren aus ihnen herausgenommen. Als er sodann diese Organe in 50% ige. Emulsion verwandelt und die Menge der Lipase durch Anwendung der Imokawaschen Methode bestimmt hatte, fand er, dass die Menge derLipase in jedem Organ mit den Veranderungen des Pankreas in einer bestimmten Bezie-hung stand. Es ergab sich namlich, dass, wenn die Krankheitsver?nderung nur in leichterem Grade auftrat, die Lipase in den einzelnen genannten Organen im Fr?hstadium der Krankheit keine Vermehrung aufwies, und das die Vermehrung erst nach 50-80 Stundenzur Beobachtung kam. Wenn aber die Veranderungen ziemlich stark eintraten, nahm die Lipase im Gegensatz zum leichten Fall vor dem Ablauf von 20-30 Stunden an Menge ab, um sich danach nicht nur nicht zu vermehren, sondern sich im allgemeinen vielmehr zu vermindern. Wenn ferner die Veranderung im hochsten Grade auftrat, d.h. bei der hochgradigen Nekrose, zeigte die Lipase in jedem Organ fast keine Vermehrung mehr. Aus der Erw?gung ?ber die St?rke der Veranderungen und die Menge der Lipase im Pankreas geht hervor, dass es, obwohl sich das Pankreas bei leichterer Veranderung in ziemlich lebhafter T?tigkeit befindet, sehr lang dauert, bis die Lipase in die Blutbahn geNangt und weiterhin in die einzelnen Organe eintritt da die Lipase nur schwer absorbiert werden kann. Daher kommt es, dass die Vermehrung der Lipase bei leichteier Krankheitsform nicht im Fr?hstadium, sondern erst im Sp?tstadium eintritt, und zwar in gerin-gem Masse. Wenn die krankhafte Ver?nderung in ziemlich starkem Masse auftritt, ge- langt die Lipase yerh?ltnismassig schnell in die einzelnen Organe, da die Pankreasfunktion dem Grad der Ver?nderungen entsprechend gesteigert wird. Was die Verringerung der Lipase im Sp?tstadium angeht, so liegt die Annahme nahe, dass die Lipase vom Pankreas nicht mehr abgesondert wird, da das Pankreas schliesslich zerst?rt wird und ihm die Funktionen verloren gehen. Wenn die Krankheitsveranderung den h?chsten Grad erreicht, so wird die Lipase im vollst?ndig zerst?rten Pankreas gar nicht erzeugt, was ihren ?bergang in die Blutbahn und auch ihre Vermehrung in den Organen unm?glich machen muss. Die Lipase wurde in den Nieren am reichlichsten angetroffen, weniger reichlich in der Leber und Milz, am wenigsten in der Lunge.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshio
en-aut-sei=Nakagawa
en-aut-mei=Yoshio
kn-aut-name=’†�ì”ü—Y
kn-aut-sei=’†�ì
kn-aut-mei=”ü—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{’ÓcŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=5
article-no=
start-page=1039
end-page=1062
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Uutersuchungen der Lipase und der ToxizitAus der Chirurgischen Klinik der Medizinischen Fakult?t Okayamat des Pankreas bei der experimentell hervorgerufenenakuten Pankreasnekrose (I. Mitteilung.) ?ber die quantitativen Schwankungen der Lipase im Blutserum und im Bauchexsudat bei experimentell hervorgerufener akuter Pankreasnekrose)
kn-title=›‰é„“I‹}�«äX‘ŸšÓŽ€Žžƒj‰—ƒPƒ‹�uƒŠƒp�[ƒ[�vâ�ƒj“Å�«ƒjè�ƒXƒ‹Œ¤‹†�i‘æ1•Ò)›‰é„“I‹}�«äX‘ŸšÓŽ€Žžƒj‰—ƒPƒ‹ŒŒ�´‹yƒr• �o�Z�o‰t’†�uƒŠƒp�[ƒ[�vƒm�Á’·ƒj�Aƒe�j
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Was das quantitative Verhalten der Lipase im Blutserum bei akuter Pankreasnekrose angeht, ist man noch nicht zu einer Einigung gekommen. W?hrend einige Forscher eine Vermehrung der Lipase annehmen, behaupten andere, sie erleide quantitativ keine Veranderungen. Auch f?r die Bestimmung der Lipase haben wir verschiedene Verfahren, unter denen das am meisten Angewandte das Verfahren von Rona-Michaelis ist. Nat?rlich hat dieses Verfahren auch manches Nacheilige. Der Verfasser hat Willst?tter, Waldschmitz und Leitz'sche methode angewandt. Er hat bei Versuchshunden durch Einf?hrung von Oliven?l, Galle, in den Ductus pancreaticus akute Pankreasnekrose hervorgerufen, um die Menge der Serumlipase in bestimmten Zeitabst?nden festzustellen. Dadurch konnte er das quantitative Verhalten der Lipase im Serum in folgende 5 Formen eingeteilt: 1) Steigende Form, bei der die Lipase nach der Operation allm?hlich zunimmt. 2) Bergform, bei der sie nach einer Zunahme wieder abnimmt. 3) Talform, bei der sie nach einer Abnahme quantitative gesteigert wird. 4) Absteigform, bei der sie nach der Operation allmahlich abnimmt. 5) Wellenform, bei der die Zu- und Abnahme sich entsprechend folgen. Unter diesen Formen zeigen die 1. und 2. eine ganz steile Erh?hung an, d.h. die quantitativen Ver?nderungen der Serunmlipase Bind auffallend gross, w?hrend die ?brigen drei Formen nur langsame Ver?nderungen geben. Die Tiere, die den ersteren Formen angeh?ren, sterben in kurzer Zeit, w?hrend die Tiere, die zu den letzteren Formen geh?ren, verh?ltnism?ssig lang am Leben bleiben. Ferner hat der Verf. in bestimmten Zeit?bstanden Blutserum und Bauchexsudate herausgenommen und die Menge der Lipase in heiden Fl?ssigkeiten bestimmt, um quantitativen Zusammenhang zwischen den Lipasen der beiden Fl?ssigkeiten festzustellen Dabei wurden folgende 4 Formen beobachtet: 1) I. Form, bei der die Lipase der Bauchexsudate abnimmt, w?hrend die Serumlipase zunimmt. 2) II. Form, bei der die Lipase der Bauchexsudate zunimmt, w?hrend die Serumlipase abnimmt. 3) III. Form, bei der die Lipase der Bauchexsudate sowie die Serumlipase zunehmen. 4) IV. Form, bei der die beiden Lipasen abnehmen. Es muss angenommen werden, dass bei der I. Form die Lipase der Bauchexunate ins Blut resorbiert wird, und class bei der II. Form dagegen eine solche Resorption nicht zustande kommt und infolgedessen das Serum nicht zunimmt. Ferner nimmt der Verf. an, dass bei der III. Form die Vermehrung der Lipase in den Exsudaten so intensiv vonstatten ging, dass auch die Serumlipase zunahm. Bei der IV. Form muss die Lipase der Bauchexsudate zwar in das Blut resorbiert worden sein, wurde aber sofort aus der Niere ausgeschieden, so dass ihre Vermehrune in den beiden Fl?ssigkeiten nicht eintrat.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshio
en-aut-sei=Nakagawa
en-aut-mei=Yoshio
kn-aut-name=’†�ì”ü—Y
kn-aut-sei=’†�ì
kn-aut-mei=”ü—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{’ÓcŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=3
article-no=
start-page=626
end-page=634
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Ein Fall von Dottergangfisteln
kn-title=ä`’°ŠÇᑃm1—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) Bericht ?ber einen Fall. von Dottergangfisteln, die sich bei einem Knaben von 7 Lebensmonaten infolge von angeborener Missbildung entwickelt hatten. Die Schleimhaut der Fistel prolabierte ein wenig. Durch Ausschneidung des Fistelgangs wurde eine vollst?ndige Heilung erzielt. 2) Beim Vorhandensein einer solchen Fistel kann es schliesslich zum Prolaps von Darmkan?lchen kommen. Die Prognose ist dann eine durchaus ung?nstige. Die-moglichst fr?hzeitige Exstirpation des Fistelgangs wird als die Methode der Wahl angesehen.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshio
en-aut-sei=Nakagawa
en-aut-mei=Yoshio
kn-aut-name=’†�ì”ü—Y
kn-aut-sei=’†�ì
kn-aut-mei=”ü—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{’ÓcŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=2
article-no=
start-page=380
end-page=388
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Ein Fall von Mischgeschwulst an der Inguinalgegend
kn-title=‘læü•”�¬�‡Žîᇃm1—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Der Pat. war ein 45 j?hriger Mann. Vor drei Jahren hat er einen Tumor in der Mitte der rechten Inguinalgegend bemerkt. Der Tumor, der am Anfang nicht grosser als die Spitze des Kleinfingers war, nahm allmahlich an Gr?sse. zu und wurde endlich so gross wie eine Faust. Beim operativen Eingriff liess sich der Tumor ohne Schwierigkeit exstirpieren, da er unter der Haut entstanden und mit der Umgebung nicht verwachsen war. Er war 11�~6�~9cm gross. Seine Schnittfl?mche zeigte eine Reihe von kleinen rundlichen Teilen. Seine Peripherie zeigte eine myxomat?se braune Farbe. In der Mitte lag ein lipomat?ser Teil, der gelblich gef?mrbt war. An der Grenze dieser beiden Teile war ein Knorpel vorhanden. Die histologische Untersuchung ergab, dass es sich hier um ein Fibro-myxo-lipo-chondrom handelte. Es war n?mlich eine mesenchymare Mischgeschwulst, die subkutan in der rechten Inguinalgegend auftrat. Wegen dieser Lage stellte dieser Tumor eine besondere Seltenheit dar.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshio
en-aut-sei=Nakagawa
en-aut-mei=Yoshio
kn-aut-name=’†�ì”ü—Y
kn-aut-sei=’†�ì
kn-aut-mei=”ü—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{’ÓcŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=1
article-no=
start-page=154
end-page=161
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1941
dt-pub=19410131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Ein Fall von kleinem Hodentumor
kn-title=�Å�¬ƒiƒ‹áΊێîá‡
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Der Verf. berichtet ?ber einen Fall von einem ?usserst kleinen Seminom, das er operativ behandelt hat. Der Pat. war ein Knabe von 31 Monaten; er hatte in dem rechten Hoden einen 2.5�~1.5cm grossen Tumor. Aus statistischen Beobachtungen wissen wir, dass unter den Hodentumoren von Kindern Krebs am h?ufigsten vorkommt. weniger h?ufig Teratam, am wenigsten oder vielmehr sehr selten Mischgeschwulst und Seminom. Was das Entstehungsalter anbetrifft, so begegnetman diese Neubildungen am h?ufigsten im Zeitraum von der Geburt bis zum Alter von 5 Jahren., Die Therapie besteht in sofortiger Exstirpation der Neubildungen, und zwar nicht nur in malignen F?llen, sondern auch in solchen F?llen, in denen die B?sartigkeit des Tumors nicht sicher ist.Nur die sofortige Exstirpation befreit das Kind von den so oft eintretenden Metastasen und Rezidiven von Hodentumor, die sich oft ?usserst b?sartig entwickeln k?nnen.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshio
en-aut-sei=Nakagawa
en-aut-mei=Yoshio
kn-aut-name=’†�ì”ü—Y
kn-aut-sei=’†�ì
kn-aut-mei=”ü—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{’ÓcŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=63
cd-vols=
no-issue=2
article-no=
start-page=37
end-page=43
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1951
dt-pub=19510331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=‰ß‹ŽŒÜƒP”NŠÔác‹³Žº‚É“ü‰@‚µ‚½ä[”X�ÇŠ³ŽÒ‚ÉŽŽ‚Ý‚½—ÕଓI�”“�Œv�i�³‘O�j
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=ŽR‰ªŒ›“ñ
kn-aut-sei=ŽR‰ª
kn-aut-mei=Œ›“ñ
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=’†�ì“ñ˜Y
kn-aut-sei=’†�ì
kn-aut-mei=“ñ˜Y
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{‘æˆê�iŽR‰ª�j“à‰È‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽRçΉȑå›{‘æˆê�iŽR‰ª�j“à‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=63
cd-vols=
no-issue=1
article-no=
start-page=1
end-page=7
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1951
dt-pub=19510131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=‰ß‹ŽŒÜƒP”NŠÔác‹³Žº‚É“ü‰@‚µ‚½ä[”X�ÇŠ³ŽÒ‚ÉŽŽ‚Ý‚½—ÕଓI�”“�Œv
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=ŽR‰ªŒ›“ñ
kn-aut-sei=ŽR‰ª
kn-aut-mei=Œ›“ñ
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=’†�ì“ñ˜Y
kn-aut-sei=’†�ì
kn-aut-mei=“ñ˜Y
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽRçΉȑå›{‘æˆê�iŽR‰ª�j“à‰È‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽRçΉȑå›{‘æˆê�iŽR‰ª�j“à‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=8
article-no=
start-page=1675
end-page=1685
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the immunity of Newcastle disease virus Part III: The toxin of Newcastle disease virus
kn-title=Newcastle Disease Virus‚̖Ɖu‚ÉŠÖ‚·‚錤‹† ‘æ3•Ò Newcastle disease virus‚Ì“Å‘f‚ÌŒ¤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=There have been made few reports on the virus toxins except those of psitacossis-lymphogranuloma and influenza groups, and, as to the Newcastle disease virus, the existence of its toxin is only presumed by Upton. Considering the fact that this toxin is neutralized by the immune serum of Newcastle disease virus, this toxin seems to have some relationship with the immunity of the virus. Therefore, the author makes reports on the fact that the Newcastle disease virus has its toxin, and about the various results gained by studying its properties. 1) The intraveneous and intraabdominal injection of the chorioallantoic fluid inoculated with this virus, could kill the injected hosts such as chickens and mice. In the case of chickens, it took less than 24 hours to kill, and in the case of mice, the animals died with convulsion. 2) This toxic substance seems to be the virus itself, because the virulence of this toxin and the concentration of virus went parallel to each other and this toxin was not able to be separated from the virus by means of kaolin-adsorption and-dissociation. 3) This virus proliferated for 48 hours in embryonated eggs showed greater virulence than that proliferated for 24 hours. In this test, however, the quantities of virus were adjusted that their infectious titer might be the same one. 4) If this virus is kept at 6�‹C, it lost its virulence earlier than the infectious titer. Against heating, however, this virulence was a little more stable than the infectious titer, and, in the presence of formalin, these two were lost parallel to each other. 5) The lethal toxin of Newcastle disease virus was neutralized by antiserum and was also neutralized in the bodies of immunized hosts.
en-copyright=
kn-copyright=

en-aut-name=NakagawaFumio
en-aut-sei=Nakagawa
en-aut-mei=Fumio
kn-aut-name=’†�앶—Y
kn-aut-sei=’†�ì
kn-aut-mei=•¶—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”�׋ۊw‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=8
article-no=
start-page=1661
end-page=1673
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the immunity of Newcastle disease virus Part II: The antigenicity of Newcastle disease virus produced from the hosts' organs infected with it
kn-title=Newcastle Disease Virus‚̖Ɖu‚ÉŠÖ‚·‚錤‹† ‘æ2•Ò Š´�õ“®•¨‘ŸŠí‚æ‚è‚‚­‚‚½Newcastle virus vaccine‚Ì�RŒ´�«‚É�A‚Ä
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Although there are many investigations about the effects of various antigens of the Newcastle disease virus, the author makes reports on the antigenicity of this virus and also on the immune effects of various fractions obtained on the way of purification of the used materials. The materials chosen for this research were the fowl brains and chick-embryos infected with this virus. 1) In the case where the tissue emulsion was chosen as vaccine, the emulsized tissue as it was had very remarkable effect. 2) Whether formal dehyde or merzonin may be used for inactivation, the immune effect remained to the same degree. 3) The condensation of chorioallantoic fluid to one-fifth of it by Brumfield's methanol sedimentation method, showed great loss of antigenicity, having the hemagglutination and infectious titers of only one-second of those of the original chorioallantoic fluid. 4) The purified and non-purified antigens of the infected chorioallantoic fluid and of 10% emulsions of the fowl brains and chick-embyros were inoculated into the hearts of chickens. Then the purified antigen of chorioallantoic fluid and non-purified antigen of emulsized chick-embryos showed better results than the others, in all of the tests of sen sitized cell agglutination, hemagglutination and of protection against infection. 5) The Newcastle disease virus had its kaolin-adsorption and -dissociation points at pH 4.0 and 8.0 respectively, and the adsorption on kaolin was well performed by repeating it twice. 6) Studying the nitrogen quantity and infectious titer of the kaolin-adsorption and -dissociation products of 10% fowl brain emulsions, the supernatant of adsorption was rich in tissue components and poor in viruses, but that of dissociation was rich in viruses and poor in tissue components. 7) The portion, which is rich in tissue elements and poor in viruses, showed greater antigenicity than the other portion, when they were inactivated and inoculated into chick-hearts. Considering the above-mentioned results, the emulsized chick-embryos as these are seem to be the best one as the antigen of Newcastle disease virus, in view of the intensity of the antigenicity, and the possibility of intramuscular injection and mass production.
en-copyright=
kn-copyright=

en-aut-name=NakagawaFumio
en-aut-sei=Nakagawa
en-aut-mei=Fumio
kn-aut-name=’†�앶—Y
kn-aut-sei=’†�ì
kn-aut-mei=•¶—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”�׋ۊw‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=8
article-no=
start-page=1647
end-page=1660
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1954
dt-pub=19540831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the immunity of Newcastle disease virus Part I: The immune reaction of Newcastle diease virus
kn-title=Newcastle Disease Virus‚̖Ɖu‚ÉŠÖ‚·‚錤‹† ‘æ1•Ò Newcastle Disease Virus‚̖Ɖu”½‰ž‚É�A‚Ä
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Although there have been made many reports that the infection and vaccination of Neweastle disease virus can produce high immunity, the vaccination in the case of virus diseases is, still now, not sufficiently effective. This experiment is performed to make some contribution to the production of general virus vaccines, by studying the problems of immunity engendered with inactivated vaccines. Here the author makes reports on the results of re-examination of various serum reactions, which are often applied to immune rections, and, at the same time, on the various new facts observed through this experiment. The materials used for this experiment were the emulsions of the fowl brains and embryos, and chorioallantoic fluid. The strain of virus used was Miyadera strain of Newcastle disease virus. 1) The LD50 of this strain for the embryonated eggs, 3-day chickens, 20-day chickens and 35-day chickens were 10-11.5, 10-15.5, 10-13.1 and 10-4.8 respectively. Therefore, the infectious titer falls remarkably as the age of chickens increases. 2) The positive titers of Hirst's phenomenon of this Miyadera strain were from 320 to 1280, and hemagglutination test with fowl immune serum showed inhibitation titers from 320 to 640. 3) The guinea-pig serum, immunized with Newcastle disease virus-infected chorioallantoic fluid, showed complement fixation with the antigen of chorioallantoic membrane, with the antigen separated with kaolin from chorioallantoic fluid, and the antigen purified from chick-embryos. In this case, the condensation of purified antigen is not so necessary. 4) Complement fixation inhibitation is completed by using the fowl immune serum. 5) The neutralization with fowl immune serum drawn on the fifteenth and thirty-fifth day after injection of the antigen, showed the log. neutralization of 3.1 and 3.7 respectively. 6) The sensitized red cell agglutination was tested with the serum drawn, as days went by after the inoculation, from the adult fowls inoculated with Newcastle disease virus-infected chorioallantoic fluid. This agglutination test showed the maximum positive titer of 640 on the sixth or eighth day and disappeared on the twenty-second day after the inoculation. 7) As to the hemagglutination inhibitation test, however, it showed the maximum titer of 640 on the twenty-second day, but, on the thirty-fifth day, it fell to fairly low titer. 8) The log. neutralization showed the maximum titer of 5.5 on the twenty-second day after inoculation, but, on the thirty-fifth day, it fell to 5.2, the same titer as that on tho twenty-second day.
en-copyright=
kn-copyright=

en-aut-name=NakagawaFumio
en-aut-sei=Nakagawa
en-aut-mei=Fumio
kn-aut-name=’†�앶—Y
kn-aut-sei=’†�ì
kn-aut-mei=•¶—Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”�׋ۊw‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=24
cd-vols=
no-issue=3
article-no=
start-page=1
end-page=29
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=19921125
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Lural Life in Kanagawa Prefecture in the Late Meiji Era (I)
kn-title=–¾Ž¡ŒãŠú‚Ì�_“Þ�쌧ˆê”_‘º‚É‚¨‚¯‚鑺–¯�¶Šˆ�\�_“Þ�쌧“s’}ŒS’†�쑺‚Ì�u‘º�¥’²�¸�‘�n‚É‚æ‚錟“¢�\�iI�j
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=KandatsuHaruki
en-aut-sei=Kandatsu
en-aut-mei=Haruki
kn-aut-name=�_—§�tŽ÷
kn-aut-sei=�_—§
kn-aut-mei=�tŽ÷
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=25
cd-vols=
no-issue=1-2
article-no=
start-page=125
end-page=150
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1993
dt-pub=19930525
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Rural Life in Kanagawa Prefecture in the Late Meiji Era (II)
kn-title=–¾Ž¡ŒãŠú‚Ì�_“Þ�쌧ˆê”_‘º‚É‚¨‚¯‚鑺–¯�¶Šˆ�\�_“Þ�쌧“s’}ŒS’†�쑺‚Ì�u‘º�¥’²�¸�‘�v‚É‚æ‚錟“¢�\(2)
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=KandatsuHaruki
en-aut-sei=Kandatsu
en-aut-mei=Haruki
kn-aut-name=�_—§�tŽ÷
kn-aut-sei=�_—§
kn-aut-mei=�tŽ÷
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=102
cd-vols=
no-issue=9-10
article-no=
start-page=1127
end-page=1134
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199010
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the reactivity of human basophilic leukocytes Part 2. Correlation between morphological changes of human basophilic leukocytes and histamine release after stimulation with Ca. ionophore A23187
kn-title=�D‰–Šî‹…‚Ì”½‰ž�«‚ÉŠÖ‚·‚錤‹† ‘æ2•Ò Ca. ionophore A23187ŽhŒƒŽž‚Ì�D‰–Šî‹…‚ÌŒoŽž“IŒ`‘Ô“I•Ï‰»‚ƃqƒXƒ^ƒ~ƒ“—V—£
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Morphological changes in human basophils from 11 atopic asthmatics were observed in whole blood smears with respect to histamine release after the cells were challenged by Ca. ionophore A23187. A decreased number of basophils and granules in the cells as well as increase in cell diameters were observed upon histamine release after stimulation with Ca. ionophore A23187. Compared to cell reactions to antigen or anti-IgE, Ca. ionophore A23187 produced both more gradual morphological changes and histamine release and induced greater increases in the diameter of the basophils. No change in the ratio of the short to long axis diameter was observed after stimulation with Ca. ionophore A23187. The results suggest that basophils do not show any increased mobility upon stimulaion with Ca. ionophore A23187, though antigen and anti-IgE stimulation induces increased motility in these cells.
en-copyright=
kn-copyright=

en-aut-name=NakagawaSaburo
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affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰ÈŠw‹³Žº
en-keyword=‹CŠÇŽxšb‘§
kn-keyword=‹CŠÇŽxšb‘§
en-keyword=�D‰–Šî‹…
kn-keyword=�D‰–Šî‹…
en-keyword=ƒqƒXƒ^ƒ~ƒ“—V—£
kn-keyword=ƒqƒXƒ^ƒ~ƒ“—V—£
en-keyword=Œ`‘Ô“I•Ï‰»
kn-keyword=Œ`‘Ô“I•Ï‰»
en-keyword=Ca. ionophore A23187
kn-keyword=Ca. ionophore A23187
END

start-ver=1.4
cd-journal=joma
no-vol=102
cd-vols=
no-issue=9-10
article-no=
start-page=1119
end-page=1126
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199010
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the reactivity of human basophilic leukocytes Part 1. Correlation between morphological changes of human basophilic leukocytes and histamine release after stimulation with antigen or anti-IgE
kn-title=�D‰–Šî‹…‚Ì”½‰ž�«‚ÉŠÖ‚·‚錤‹† ‘æ1•Ò �RŒ´�C�RƒqƒgIgEŽhŒƒŽž‚Ì�D‰–Šî‹…‚ÌŒoŽž“IŒ`‘Ô“I•Ï‰»‚ƃqƒXƒ^ƒ~ƒ“—V—£
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Morphological changes in human basophils from atopic asthmatics were observed in whole blood smears with respect to histamine release after stimulation with antigen or anti-IgE. Histamine was rapidly released and was accompanied by morphological changes in basophils upon stimulation with antigen and anti-IgE. A decreased number of basophils and morphological changes including increased cell diameters, increased ratios of the short to long axis diameters, and decreased intracellular granule counts were observed upon the release of histamine after antigen and anti-IgE stimulation. Antigen stimulus induced both more rapid histamine release and morphological changes than anti-IgE stimulation.
en-copyright=
kn-copyright=

en-aut-name=NakagawaSaburo
en-aut-sei=Nakagawa
en-aut-mei=Saburo
kn-aut-name=’†�ìŽO˜Y
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kn-aut-mei=ŽO˜Y
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ORCID=

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kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰ÈŠw‹³Žº
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kn-keyword=‹CŠÇŽxšb‘§
en-keyword=�D‰–Šî‹…
kn-keyword=�D‰–Šî‹…
en-keyword=Œ`‘Ô“I•Ï‰»
kn-keyword=Œ`‘Ô“I•Ï‰»
en-keyword=“ÁˆÙ�RŒ´
kn-keyword=“ÁˆÙ�RŒ´
en-keyword=�RƒqƒgIgE
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END

start-ver=1.4
cd-journal=joma
no-vol=122
cd-vols=
no-issue=3
article-no=
start-page=231
end-page=236
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20101201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of transverse colon cancer with remarkable extramural invasion to stomach and jejunum
kn-title=•ÇŠO�«‚ÉŽîᎂðŒ`�¬‚µˆÝ�E�¬’°�Z��‚ðŽ¦‚µ‚½‰¡�sŒ‹’°Šà‚Ì‚P—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 77-year-old woman was admitted to our hospital due to abdominal pain and body weight loss. A palpable mass the size of an infant's head was tender on palpation and identified as an epigastric lesion. Colonoscopic examination revealed stenosis of the transverse colon, although no intraluminal growth of the tumor was found. The histologic findings of the biopsy material were poorly differentiated and/or undifferentiated cells. Abdominal CT scan showed an irregular-shaped tumor with a diameter of 10cm invading the stomach and jejunum. We performed an operation under a diagnosis of extramurally growing cancer or malignant lymphoma of the colon. Partial resection of the transverse colon was done by distal gastrectomy and partial resection of the jejunum. Histologic examination of the operative specimens revealed moderately differentiated adenocarcinoma of the transverse colon, prominently proliferating into the surrounding tissues. The finding of a long stenotic lesion and extramural compression by colonography are characteristic of this tumor, based on a review of 43 literature reports in Japan.
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en-aut-name=HamanoRyosuke
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en-aut-mei=Ryosuke
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en-aut-name=OtsukaShinya
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kn-aut-mei=áÁ�Æ
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en-aut-name=KimuraYuuji
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en-aut-mei=Yuuji
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en-aut-name=NishieManabu
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kn-aut-name=�¼�]Šw
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en-aut-name=TokunagaNaoyuki
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en-aut-name=MiyasouHideaki
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en-aut-mei=Hideaki
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en-aut-name=TsunemituYousuke
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en-aut-name=InagakiMasaru
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en-aut-mei=Masaru
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kn-aut-mei=—D
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en-aut-name=IwakawaKazuhide
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en-aut-mei=Kazuhide
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en-aut-name=IwagakiHiromi
en-aut-sei=Iwagaki
en-aut-mei=Hiromi
kn-aut-name=ŠâŠ_”Ž–¤
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affil-num=1
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kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=2
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=3
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=4
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=5
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=6
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=7
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=8
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=9
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È

affil-num=10
en-affil=
kn-affil=�‘—§•a‰@‹@�\•ŸŽRˆã—ÃZƒ“ƒ^�[�@ŠO‰È
en-keyword=‘å’°Šà (colon cancer)
kn-keyword=‘å’°Šà (colon cancer)
en-keyword=•ÇŠO�«”­ˆç (extraluminal growth)
kn-keyword=•ÇŠO�«”­ˆç (extraluminal growth)
END

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cd-journal=joma
no-vol=
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start-page=
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dt-received=
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dt-pub-year=2010
dt-pub=20100325
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en-article=
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en-title=�³�í‚ƃAƒJƒ^ƒ‰ƒZƒ~ƒA‚ȃ}ƒEƒX‚ÌŠÔ‚É‘S�g�ÆŽË‚É‚æ‚é•úŽË�üŠ´Žó�«‚É�·ˆÙ‚Í‚È‚¢
kn-title=No Different Sensitivity in Terms of Whole-body Irradiation Between Normal and Acatalasemic Mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaShinya
en-aut-sei=Nakagawa
en-aut-mei=Shinya
kn-aut-name=’†�ì�T–ç
kn-aut-sei=’†�ì
kn-aut-mei=�T–ç
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw
END

start-ver=1.4
cd-journal=joma
no-vol=54
cd-vols=
no-issue=
article-no=
start-page=35
end-page=38
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1984
dt-pub=19840325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=�D‰–Šî‹…‚©‚ç‚̃qƒXƒ^ƒ~ƒ“—V—£‚ÉŠÖ‚·‚錤‹†. 3. �RƒqƒgIgE ‚ɑ΂·‚é�D‰–Šî‹…‚Ì”½‰ž�«‚Æ––�½ŒŒ�DŽ_‹…‘�‘½
kn-title=Studies on the release of histamine from basophils. 3. Correlation between basophil reactivity to anti-IgE and blood eosinophilia
en-subtitle=
kn-subtitle=
en-abstract=––�½ŒŒ�DŽ_‹…‘�‘½‚ðŽ¦‚·‹CŠÇŽxšb‘§14�Ç—á‚ɂ‚¢‚Ä,�RƒqƒgIgE ‚É‚æ‚é�D‰–Šî‹…‚©‚ç‚̃qƒXƒ^ƒ~ƒ“—V—£‚ðŒŸ“¢‚µ‚½. ƒnƒEƒXƒ_ƒXƒg‚ɑ΂·‚é”ç“à”½‰ž‚¨‚æ‚ÑRAST‚ª—z�«‚ðŽ¦‚·�Ç—áŒQ(groupI)‚Å‚Í,ŒŒ�´IgE’l‚ª�‚‚­,‚Ü‚½�RƒqƒgIgE‚É‚æ‚éMax. % ƒqƒXƒ^ƒ~ƒ“—V—£‚à�‚‚­(50.7Žm5.0%),‚»‚Ìdoseresponse curve‚Í�RƒqƒgIgE“Y‰Á”Z“x‚ª�‚‚­‚È‚é‚ɂ‚ê‚Ä�ã�¸‚·‚éŒXŒü‚ðŽ¦‚µ‚½.ˆê•ûŽí�X‚̃AƒŒƒ‹ƒQƒ“ƒGƒLƒX‚ɑ΂·‚é”ç“à”½‰ž‚ª‰A�«‚Å,‚©‚ÂRAST ‚à‰A�«‚ðŽ¦‚·�Ç—áŒQ(group II)‚Å‚Í,ŒŒ�´IgE’l‚ª’á‚­,‚Ü‚½�RƒqƒgIgE‚É‚æ‚éMax. % ƒqƒXƒ^ƒ~ƒ“—V—£‚à’á‚­(10.5Žm1.7%),‚»‚Ìdose-response curve‚Í‘S”Ê“I‚É’á‚­,�RƒqƒgIgE“Y‰Á”Z“x‚ª�‚‚¢‚Æ‚±‚ë‚Å‚Í‚Þ‚µ‚ë—}�§‚³‚ê‚éŒXŒü‚ðŽ¦‚µ‚½.
kn-abstract=Histamine release from basophils induced by anti-IgE was examined in 14 asthmatic subjects with blood eosinophilia. The subjects were divided into two groups; group I (with blood eosinophilia, positive skin test and positive RAST to house dust) and group II (with blood eosinophilia, negative skin test to various allergens and negative RAST to house dust). 1. Serum IgE levels in group I were much higher than those in group II. 2. Maximum percent histamine release induced by anti-IgE was much higher in group I than in group II. 3. Dose-response curve of anti-IgE-induced histamine release in group I showed consistent increase as anti-IgE concentrations increased. while, dose-response curve in group II was very low. These findings suggested that blood eosinophilia in group I might be elicited relating to IgE-mediated reaction. However, mechanism causing eosinophilia in group II was not clear in the present study.
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=’J�è�Ÿ˜N
kn-aut-sei=’J�è
kn-aut-mei=�Ÿ˜N
aut-affil-num=1
ORCID=

en-aut-name=KomagoeHaruki
en-aut-sei=Komagoe
en-aut-mei=Haruki
kn-aut-name=‹î‰z�tŽ÷
kn-aut-sei=‹î‰z
kn-aut-mei=�tŽ÷
aut-affil-num=2
ORCID=

en-aut-name=SudoMichiyasu
en-aut-sei=Sudo
en-aut-mei=Michiyasu
kn-aut-name=Žü“¡�^�N
kn-aut-sei=Žü“¡
kn-aut-mei=�^�N
aut-affil-num=3
ORCID=

en-aut-name=MifuneMasaaki
en-aut-sei=Mifune
en-aut-mei=Masaaki
kn-aut-name=Œä”Ê�­–¾
kn-aut-sei=Œä”Ê
kn-aut-mei=�­–¾
aut-affil-num=4
ORCID=

en-aut-name=MorinagaHiroshi
en-aut-sei=Morinaga
en-aut-mei=Hiroshi
kn-aut-name=�X‰iŠ°
kn-aut-sei=�X‰i
kn-aut-mei=Š°
aut-affil-num=5
ORCID=

en-aut-name=NakagawaSaburo
en-aut-sei=Nakagawa
en-aut-mei=Saburo
kn-aut-name=’†�ìŽO˜Y
kn-aut-sei=’†�ì
kn-aut-mei=ŽO˜Y
aut-affil-num=6
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=‹M’JŒõ
kn-aut-sei=‹M’J
kn-aut-mei=Λ
aut-affil-num=7
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=–Ø‘ºˆè˜Y
kn-aut-sei=ЯԼ
kn-aut-mei=ˆè˜Y
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ2“à‰È

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ2“à‰È

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ2“à‰È
END

start-ver=1.4
cd-journal=joma
no-vol=55
cd-vols=
no-issue=
article-no=
start-page=7
end-page=10
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1984
dt-pub=19841130
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Spa therapy for patients with chronic obstructive lung disease
kn-title=Studies on the release of histamine from basophils 4. Difference between house dust- and Candida-induced secretion
en-subtitle=
kn-subtitle=
en-abstract=ƒnƒEƒXƒ_ƒXƒg‚ ‚é‚¢‚̓Jƒ“ƒWƒ_‚ª“ÁˆÙ�RŒ´‚Å‚ ‚é‹CŠÇŽxšb‘§30—á‚ð‘Î�Û‚É,‚»‚ꂼ‚ê‚Ì�RŒ´ŽhŒƒŽž‚Ì�D‰–Šî‹…‚©‚ç‚̃qƒXƒ^ƒ~ƒ“—V—£‚ð,�RƒqƒgIgE‚É‚æ‚é—V—£‚Æ”äŠrŒŸ“¢‚µ‚½. 1. ƒnƒEƒXƒ_ƒXƒg‚ªŒ´ˆö�RŒ´‚Å‚ ‚é�Ç—á‚Ì�D‰–Šî‹…‚©‚ç‚̃qƒXƒ^ƒ~ƒ“—V—£‚Í,�RŒ´ŽhŒƒŽž41.8%,�RƒqƒgIgEŽhŒƒŽž40.8%‚Å‚ ‚Á‚½. 2. ƒJƒ“ƒWƒ_‚ªŒ´ˆö�RŒ´‚Å‚ ‚é�Ç—á‚Ì�D‰–Šî‹…‚©‚ç‚̃qƒXƒ^ƒ~ƒ“—V—£‚Í,�RŒ´ŽhŒƒŽž27.1%,�RƒqƒgIgEŽhŒƒŽž32.2%‚Å‚ ‚Á‚½. 3. ƒnƒEƒXƒ_ƒXƒg‚Æ�RƒqƒgIgE‚É‚æ‚é�D‰–Šî‹…‚©‚ç‚̃qƒXƒ^ƒ~ƒ“—V—£‚Í,‚Ù‚Ú“¯—l‚Ì’l‚ðŽ¦‚µ‚½. ˆê•ûƒJƒ“ƒWƒ_‚Æ�RƒqƒgIgE‚É‚æ‚éƒqƒXƒ^ƒ~ƒ“—V—£‚ÌŠÔ‚É‚Í—LˆÓ‚Ì
‘ŠŠÖŠÖŒW‚Í‚Ý‚ç‚ê‚È‚©‚Á‚½.
kn-abstract=Histamine releasse from basophils induced by house dust and C. albicans was examined in 30 patients with bronchial asthma. House dust and C. albicans caused a significant amount of histamine release in subjects with a RAST score to corresponding allergen. A close correlation was found between house dust- and anti-IgE-induced histamine release. However, histamine release induced by C. albicans was considerably different from the release induced by anti-IgE.
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=’J�è�Ÿ˜N
kn-aut-sei=’J�è
kn-aut-mei=�Ÿ˜N
aut-affil-num=1
ORCID=

en-aut-name=KomagoeHaruki
en-aut-sei=Komagoe
en-aut-mei=Haruki
kn-aut-name=‹î‰z�tŽ÷
kn-aut-sei=‹î‰z
kn-aut-mei=�tŽ÷
aut-affil-num=2
ORCID=

en-aut-name=SudoMichiyasu
en-aut-sei=Sudo
en-aut-mei=Michiyasu
kn-aut-name=Žü“¡�^�N
kn-aut-sei=Žü“¡
kn-aut-mei=�^�N
aut-affil-num=3
ORCID=

en-aut-name=MorinagaHiroshi
en-aut-sei=Morinaga
en-aut-mei=Hiroshi
kn-aut-name=�X‰iŠ°
kn-aut-sei=�X‰i
kn-aut-mei=Š°
aut-affil-num=4
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=‹M’JŒõ
kn-aut-sei=‹M’J
kn-aut-mei=Λ
aut-affil-num=5
ORCID=

en-aut-name=NakagawaSaburo
en-aut-sei=Nakagawa
en-aut-mei=Saburo
kn-aut-name=’†�ìŽO˜Y
kn-aut-sei=’†�ì
kn-aut-mei=ŽO˜Y
aut-affil-num=6
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=–Ø‘ºˆè˜Y
kn-aut-sei=ЯԼ
kn-aut-mei=ˆè˜Y
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwŽO’©•ª‰@“à‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwŽO’©•ª‰@“à‰È

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwŽO’©•ª‰@“à‰È

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwŽO’©•ª‰@“à‰È

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠw‘æ2“à‰È

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠw‘æ2“à‰È

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠw‘æ2“à‰È
END

start-ver=1.4
cd-journal=joma
no-vol=2009
cd-vols=
no-issue=1
article-no=
start-page=111
end-page=116
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2009
dt-pub=20091111
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Design Support of Transportation Routing for a Multi Layered Factory
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Recently, it becomes important to improve transportation capability to attain high productivity in manufacturing. One of the necessary schemes to attain the purpose is that the floor layout is initially to be optimized. After the floor layout is determined, reasonable equipment position for transportation is decided. Then the design of the transportation route is to be determined. In this paper, design support system for transportation routing, based on agent method is proposed. To optimize the transportation route, the working space by the side of the equipment is to be prepared. Starting from given floor layout of a three layered factory, an appropriate transportation route is pursuit using Ant algorithm. To check the applicability of the proposed method, case studies are carried out under various constraints and objective functions, and its effects were verified.
en-copyright=
kn-copyright=

en-aut-name=NakagawaKoji
en-aut-sei=Nakagawa
en-aut-mei=Koji
kn-aut-name=’†�ìŒõ˜H
kn-aut-sei=’†�ì
kn-aut-mei=Œõ˜H
aut-affil-num=1
ORCID=

en-aut-name=KonishiMasami
en-aut-sei=Konishi
en-aut-mei=Masami
kn-aut-name=�¬�¼�³çZ
kn-aut-sei=�¬�¼
kn-aut-mei=�³çZ
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=Okayama University

affil-num=2
en-affil=
kn-affil=Okayama University
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=5
article-no=
start-page=1609
end-page=1615
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1958
dt-pub=19580531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical and Experimental Studies on the Artificial Hypotensive Operation. Part ‡X. Experimental Comparative Studies on Anesthesia under Normal Blood Pressure and Hypotention Nucleic Acid in Dogs
kn-title=�lˆ×’ጌˆ³‰ºŽè�p‚ÉŠÖ‚·‚é—Õ�°“I‚È‚ç‚Ñ‚ÉŽÀŒ±“IŒ¤‹† ‘æ5•Ò ŠjŽ_‚Ì�Á’·‚©‚ç‚Ý‚½�³�파ˆ³‰º–ƒ�Œ‚Æ�lˆ×’ጌˆ³‰º–ƒ�Œ‚Æ‚ÌŽÀŒ±“I”äŠrŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Male dogs were anesthetized with endotracheal anesthesia under the normal and the artificial hypotensive blood pressure and the influences of the anesthesia on the nucleic acid metabolism in the liver and the kidney were studied. 1) No marked degenerative changes were generally observed in both normal and hypotensive groups by anesthesia. 2) The influences on the nucleic acid metabolism were very slight in both groups. 3) In the hypotensive group, dilatation of the capillary vessels in the kidney and liver was observed. 4) The changes of R.N.A. seemed a little greater than those of D.N.A. in both groups, but no definite tendency was hardly observed. 5) Histological changes including the change of nucleic acid seemed stronger as the duration of anesthesia became longer and the grade of hypotention became greater. However, no marked difference observed between 2 and 3.5 hours of anesthesia and between 20% and 40% of hypotensive rate.
en-copyright=
kn-copyright=

en-aut-name=NakagawaToshimi
en-aut-sei=Nakagawa
en-aut-mei=Toshimi
kn-aut-name=’†�ì�r”ü
kn-aut-sei=’†�ì
kn-aut-mei=�r”ü
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ1�i�w“à�jŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=5
article-no=
start-page=1601
end-page=1608
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1958
dt-pub=19580531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical and Experimental Studies on the Artificial Hypotensive Operation. Part ‡W. Comparative Studies of Surgical Operations under Normal Blood Pressure and Hypotension regarding Renal Function
kn-title=�lˆ×’ጌˆ³‰ºŽè�p‚ÉŠÖ‚·‚é—Õ�°“I‚È‚ç‚Ñ‚ÉŽÀŒ±“IŒ¤‹† ‘æ4•Ò �t‹@”\‚©‚ç‚Ý‚½�³�파ˆ³‰ºŽè�p‚Æ�lˆ×’ጌˆ³‰ºŽè�p‚Æ‚Ì”äŠrŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The cases of pulmonary resection under endotracheal anesthsia of closed circulation were divided into two groups, i.e. the normal blood pressure group and the hypotensive group, and the glomerular filtration rate (C.F.R.) and the tubular reabsorption rate (T.R.R.) were evaluated in each group. 1) G.F.R. markedly decreased during operation in both groups and restored almost to the preoperative G.F.R. after recovery. 2) The hypotensive group showed a little more marked decrease of G.F.R. during and after operation than the normal group. The volume of urine showed a similar change to G.F.R. 3) T.R.R. showed no change before, during and after operation proved to be due to the decrease of G.F.R.
en-copyright=
kn-copyright=

en-aut-name=NakagawaToshimi
en-aut-sei=Nakagawa
en-aut-mei=Toshimi
kn-aut-name=’†�ì�r”ü
kn-aut-sei=’†�ì
kn-aut-mei=�r”ü
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ1�i�w“à�jŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=5
article-no=
start-page=1589
end-page=1600
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1958
dt-pub=19580531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical and Experimental Studies on the Artificial Hypotensive Operation. Part ‡V. Comparative Studies of Surgical Operations under Normal Blood Pressure and Hypotension with Measuring of the Liver Function
kn-title=�lˆ×’ጌˆ³‰ºŽè�p‚ÉŠÖ‚·‚é—Õ�°“I‚È‚ç‚Ñ‚ÉŽÀŒ±“IŒ¤‹† ‘æ3•Ò ŠÌ‹@”\‚©‚ç‚Ý‚½�³�파ˆ³‰ºŽè�p‚Æ�lˆ×’ጌˆ³‰ºŽè�p‚Æ‚Ì”äŠrŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The influences of endothracheal anesthesia upon the liver function in the preoprative stage, during the operation and after the recovery was estimated measuring the serum bilirubin and BSP test and the results in both groups were compared. 1) The total serum bilirubin increased in both groups slightly during the opeartion and mostly after the recovery. It showed a tendency to decrease gradually at the third postoperative day. But its mean value was larger in the hypotensive group than in the normal group during the operation. After the operation, however, it was rather more in the normal group. 2) The increase of the total serum bilirubin during the operation was mostly dut to the increase of the direct and indirect bilirubin. 3) BSP-test during the operation showed an increase of 22.5%-25.7% in the blood, but it showed a marked restoratation after recovery in both groups. BSP in the blood of the normal group during the operation seemed more than that of the hypotensive group, but not different after recovery.
en-copyright=
kn-copyright=

en-aut-name=NakagawaToshimi
en-aut-sei=Nakagawa
en-aut-mei=Toshimi
kn-aut-name=’†�ì�r”ü
kn-aut-sei=’†�ì
kn-aut-mei=�r”ü
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ1�i�w“à�jŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=5
article-no=
start-page=1575
end-page=1587
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1958
dt-pub=19580531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical and Experimental Studies on the Artificial Hypotensive Operation. Part ‡U. Comparative Studies of Surgical Operations under Normal Blood Pressure and Hypotension with Analysis of Blood Gases
kn-title=�lˆ×’ጌˆ³‰ºŽè�p‚ÉŠÖ‚·‚é—Õ�°“I‚È‚ç‚Ñ‚ÉŽÀŒ±“IŒ¤‹† ‘æ2•Ò ŒŒ‰tƒKƒX‚©‚ç‚Ý‚½�³�파ˆ³‰ºŽè�p‚Æ�lˆ×’ጌˆ³‰ºŽè�p‚Æ‚Ì”äŠrŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The group of pulmonary resections under normal blood pressure and the group of those under endotracheal anesthesia of closed circulation type were compared. The arterial blood gas content was measured at the pre-operative stage, directly after the intubation, during operation and after recovery using Van Slyke manometer. The results were as follows: 1) The O(2) content of the arterial blood showed a decreasing either under normal blood pressure of under hypotensive group, most strikingly during the operation moderately after recovery, and slightly directly after the intubation. The mean values of both groups were compared. The O(2) content of the arterial blood had more definite tendency of decreasing in the hypotensive group than the normal group, but it was not significant. 2) The CO(2) content in the arterial blood in both groups generally decreased slightly directly after intubation and most strikingly during the operation. After recovery it became rather more in the normal group than before the operation, while that in the hypotensive group decreased slightly and still less than before the operation. 3) Throughout all cases we found the decreasing of total blood gases especially during the operation, namely there was a decreasing tendency of general metabolic function of gases, which was regarded to be stronger in the hypotensive group than in the normal group. 4) Though the decreasing tendency of metabolic function of gases was rather stronger in the hypotensive group than that in the normal group, the value of arterial blood was rather better in the hypotensive group. This value in both groups increased with the lapse of the stages of operation. 5) In the cases, in which the arterial blood value more than 3.0 already before the operation, we must be careful to determine the indication of pulmonary resection. We must pay close attention to it, because the patient is apt to fall into risk postoperatively even if we can safely finish the operation.
en-copyright=
kn-copyright=

en-aut-name=NakagawaToshimi
en-aut-sei=Nakagawa
en-aut-mei=Toshimi
kn-aut-name=’†�ì�r”ü
kn-aut-sei=’†�ì
kn-aut-mei=�r”ü
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ1�i�w“à�jŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=70
cd-vols=
no-issue=5
article-no=
start-page=1567
end-page=1574
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1958
dt-pub=19580531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical and Experimental Studies on the Artificial Hypotensive Operation. Part 1. Comparative Studies of Surgical Operations and ‡V Effects under the Normal Blood Pressure and Artificial Hypotensive Anesthesia
kn-title=�lˆ×’ጌˆ³‰ºŽè�p‚ÉŠÖ‚·‚é—Õ�°“I‚È‚ç‚Ñ‚ÉŽÀŒ±“IŒ¤‹† ‘æ1•Ò �³�파ˆ³‰ºŽè�p‚Æ�lˆ×’ጌˆ³‰ºŽè�p‚Æ‚Ì—Õ�°�¬�Ñ‚È‚ç‚Ñ‚É•›�ì—p‚Ì”äŠrŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) The endotracheal anesthesia of closed circulation type was applicated to 259 cases and Hexamethonium bromide (C(6)) and inclining of the operating table were used for 30 cases of pulmonary resection. 2) The dose of C(6) for the artificial hypotensive operation was on the average of 63 mg and the maximum descending of blood pressure was on the average of 34% . Generally we got to the aimed hypotention by the intravenous injection of C(6) 50 mg and inclining of the operating table. But the additional intravenous injection of C(6) did not effected so strongly as the first one. 3) The mean amount of the lost blood in the hypotensive group less than half of that in normal groups. In the hypotensive group there was a tendency to decrease the bleeding even in those cases, in which we could not get the aimed hypotension. 4) The blood and saline used during pneumectomy for hypotensive group, were less than half of those used in the normal group. 5) The tendency of postoperative bleeding as a complication was stronger in the hypotensive group. In one hypotensive case we could only make thoracotomy, because of hypoxia, but in other cases we found no noted complication.
en-copyright=
kn-copyright=

en-aut-name=NakagawaToshimi
en-aut-sei=Nakagawa
en-aut-mei=Toshimi
kn-aut-name=’†�ì�r”ü
kn-aut-sei=’†�ì
kn-aut-mei=�r”ü
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ1�i�w“à�jŠO‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=72
cd-vols=
no-issue=11-12
article-no=
start-page=2145
end-page=2150
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1960
dt-pub=19601231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An Autopsy Case of Hypoplastic Anemia occurring during the Treatment with Dilantin (Aleviatin)
kn-title=Dilantin�iAleviatin�jŽg—p’†‚É”­�Ç‚µ‚½�Ä�¶•s—Ç�«•nŒŒ‚̈ê–UŒŸ—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The authors report a case of hypoplastic anemia which suddenly attacked a female, age 23, under the treatment with Dilantin (Aleviatin), an anticonvulsant and drove her to death three weeks after the onset of the disease in spite of various therapies. The chief complaints were a high fever, subcutaneous and gingival bleeding and pharyngealgia. On admission severe hyperchromic anemia, severe leukopenia with lymphocytosis (95%), thrombopenia, hemorrhagic diathesis, angina and typical myelogram were noticed. At autopsy the bone marrow showed hypoplasia and maturation arrest. It is emphasized that the single treatment with Dilantin may produce severe hematopoietic disturbance such as hypoplastic anemia that have not been reported.
en-copyright=
kn-copyright=

en-aut-name=NakagawaShoso
en-aut-sei=Nakagawa
en-aut-mei=Shoso
kn-aut-name=’†�ì�¹‘s
kn-aut-sei=’†�ì
kn-aut-mei=�¹‘s
aut-affil-num=1
ORCID=

en-aut-name=NishimuraAtsushi
en-aut-sei=Nishimura
en-aut-mei=Atsushi
kn-aut-name=�¼‘º“Õ
kn-aut-sei=�¼‘º
kn-aut-mei=“Õ
aut-affil-num=2
ORCID=

en-aut-name=OgoHiroshi
en-aut-sei=Ogo
en-aut-mei=Hiroshi
kn-aut-name=�¬‰Í”Ž”V
kn-aut-sei=�¬‰Í
kn-aut-mei=”Ž”V
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”–…”ö•a—�Šw‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=72
cd-vols=
no-issue=11-12
article-no=
start-page=2137
end-page=2144
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1960
dt-pub=19601231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A Case of Cushing's Syndrom
kn-title=CushingŽ��ÇŒóŒQ‚̈ê—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The authors report a case of Cushing's syndrom with typical clinical pictures, that is, generalized adipositas, full moon face, cutaneous striae, hypertension, osteoporosis, hyperglycemia and excessive secretion of 17-ketosteroid and 17-hydrooxycorticoid. Although the patient had various clinical examination, the primary pathologic site was not found. It might be thought that the site is benign, since no general symptoms became worse during long course.
en-copyright=
kn-copyright=

en-aut-name=WatanabeHaruo
en-aut-sei=Watanabe
en-aut-mei=Haruo
kn-aut-name=“n•Ó�t�¶
kn-aut-sei=“n•Ó
kn-aut-mei=�t�¶
aut-affil-num=1
ORCID=

en-aut-name=MonobeTaisei
en-aut-sei=Monobe
en-aut-mei=Taisei
kn-aut-name=•¨•”‘å�¬
kn-aut-sei=•¨•”
kn-aut-mei=‘å�¬
aut-affil-num=2
ORCID=

en-aut-name=NakagawaShoso
en-aut-sei=Nakagawa
en-aut-mei=Shoso
kn-aut-name=’†�ì�¹‘s
kn-aut-sei=’†�ì
kn-aut-mei=�¹‘s
aut-affil-num=3
ORCID=

en-aut-name=ShindoMinoru
en-aut-sei=Shindo
en-aut-mei=Minoru
kn-aut-name=�i“¡–«
kn-aut-sei=�i“¡
kn-aut-mei=–«
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=72
cd-vols=
no-issue=11-12
article-no=
start-page=2133
end-page=2136
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1960
dt-pub=19601231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An Experimental Study on Occult Blood in Feces (Experiment by Oral Administration of Human Blood)
kn-title=•³•Ö�öŒŒ”½‰ž‚ÌŽÀŒ±“IŒ¤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Examinations of occult blood in feces were performed after a certain amount of blood treated previously with hydrochloric acid limonnde was given into the stomach or duodenum through a Levin tube. The follwing results were obtained. 1. All the cases were positive in the reaction after the administration of more than 2 ml. of the blood. 2. No significant difference in the reaction between intragastric and intraduodenal administration. 3. The intensity of the positive reaction became weak as the acidity in gastric juice became high. 4. The longevity of the positive reaction was prolonged with larger amount of the blood given but they were not proportional when the amount of more than 3 ml. of the blood was administrated. After 4 days all the cases showed negative reaction.
en-copyright=
kn-copyright=

en-aut-name=NakagawaShoso
en-aut-sei=Nakagawa
en-aut-mei=Shoso
kn-aut-name=’†�ì�¹‘s
kn-aut-sei=’†�ì
kn-aut-mei=�¹‘s
aut-affil-num=1
ORCID=

en-aut-name=HiranoYutaka
en-aut-sei=Hirano
en-aut-mei=Yutaka
kn-aut-name=•½–슰
kn-aut-sei=•½–ì
kn-aut-mei=Š°
aut-affil-num=2
ORCID=

en-aut-name=YamamotoYuushi
en-aut-sei=Yamamoto
en-aut-mei=Yuushi
kn-aut-name=ŽR–{—TŽm
kn-aut-sei=ŽR–{
kn-aut-mei=—TŽm
aut-affil-num=3
ORCID=

en-aut-name=GotoShoichiro
en-aut-sei=Goto
en-aut-mei=Shoichiro
kn-aut-name=Œã“¡�ºˆê˜Y
kn-aut-sei=Œã“¡
kn-aut-mei=�ºˆê˜Y
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=72
cd-vols=
no-issue=8-10
article-no=
start-page=1711
end-page=1722
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1960
dt-pub=19601030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Bile Pigment Precursors in Erythrocytes Part 2. Relationship between Bile Pigment Precursors and Free Porphyrin in Erythrocytes
kn-title=�ÔŒŒ‹…“àBile Pigment Precursors‚ÉŠÖ‚·‚錤‹† ‘æ2•Ò �ÔŒŒ‹…“àBile Pigment Precursors‚Æ�ÔŒŒ‹…“à—V—£Parphyrin‚Æ‚ÌŠÖŒW
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In order to study the possibility of porphyrin to become bile pigment precursors, the relations between free porphyrin in erythrocytes, especially protoporphyrin, and intracorpuscular bile pigment precursors were experimentally observed. The results were as follows: 1. A part of protoporphyrin which increased was observed to change quickly into bile pigment precursors in the erythrocytes of a phlebotomized anemic or phenylhydrazine HC1 administered rabbits where reticulocytosis occurred. 2. This transformation of protoporphyrin into bile pigment precursors were also observed in preserving canine erythrocytes where reticulocytosis was caused by phlebotomies. 3. Judging from the variations of intracorpuscular easily split off blood iron, it seemed appropriate to consider that this transformation occurred after the formation of hems or hemoglobin. In the above experiment, however, of preserving erythrocytes of a phlebotomized anemic dog, the plainly direct transformation of protoporphyrin into bile pigment precursors were also observed. 4. In preserving canine erythrocytes with or without the addition of ascorbic acid, the increase of protoporphyrin and of bile pigment precursors were also observed. However, it is difficult to account for the relations betwaen these two; the increase of bile pigment precursors may be ascribable to the breakdown of hemoglobin.
5. Intracorpuscular free coproporphyrin was obsarvei to increase in those erythrocytes after phlebotomies. phenylhydrazine HC1 aiministratioa, or preservation with the addition of ascorbic acid. This increase may more properly be ascribed to protoporphyrin in the formation process of hemoglobin than to bile pigment precursors. On the other hand, free uroporphyrin in erythrocytes did not show any significant variations. 6. Protoporphyrin mixed with chloroform extract did not hinder the microquantitative analysis of bile pigment precursors by fluorescence.
en-copyright=
kn-copyright=

en-aut-name=NakagawaShoso
en-aut-sei=Nakagawa
en-aut-mei=Shoso
kn-aut-name=’†�ì�¹‘s
kn-aut-sei=’†�ì
kn-aut-mei=�¹‘s
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=72
cd-vols=
no-issue=8-10
article-no=
start-page=1695
end-page=1709
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1960
dt-pub=19601030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Bile Pigment Precursors in Erythrocytes Part 1. Micro-quantitative Analysis of Bile Pigment Precursors in Erythrocytes and its Alteration in Various Experimental Conditions
kn-title=�ÔŒŒ‹…“àBile Pigment Precursors‚ÉŠÖ‚·‚錤‹† ‘æ1•Ò �ÔŒŒ‹…“àBile Pigment Precursors‚Ì”÷—Ê’è—Ê–@‚ÌŒŸ“¢‹y‚ÑŽÀŒ±“I�lŽ@
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The method of micro-quantitative analysis of bile pigment precursors in erythrocytes was studied and various experimental observations were made for the elucidation of its physiological significance. The following results were obtained: 1. Studies of the fluorescent micro-quantitative analysis made it clear that bile pigment precursors in erythrocytes can be determined in the 0.1-5.0ƒÊg/ml biliverdin chloroform solution. Observing its absorption spectrum and fluorescent spectral characteristics, it was also made clear that all the bile pigment precursors were determined by the fluorescence of choleterin zincic complex salt. 2. Gardikas' method of extracting intracorpuscular bile pigment precursors under an anaerobic condition without adding ascorbic acid proved to be better than that of R. Lemberg of extracting by adding ascorbic acid under an aerobic condition. 3. Among normal erythrocytes of various animals were found no significant specific differences, the amount of bile pigment precursors being about 15ƒÊg/Hb. 4. When dog's erythrocytes were iucubated at 37�Ž. after the addition of ascorbic acid, bile pigment precursors in them attained to a remarkably great amount within several hours. This is considered to have resulted from the action of ascorbic acid in choleglobin formation in erythrocytes. 5. 4 hours after phenylhydrazine HCl was administered to a rabbit, the amount of bile pigment precursors in erythrocytes in circulating blood began to increase and attained to its maximum in 4-48 hours. The amount of easily split off blood iron also increased in parallel with it. 6. When canine blood was taken in A.C.D. solution and kept at 4�Ž., the amount of bile pigment precursors in erythrocytes gradually increased with the course of time, showing a sudden increase after 4 weeks. The amount of easily split off blood iron showed a similar variations. 7. In the erythrocytes of a phlebotomized anemic rabbit, the amount of bile pigment precursors decreased at the same time as reticulocytes showed a remarkable increase. The amount of easily split off blood iron showed a similar tendency of decrease. 8. From the above results the following conclusions were drawn. Bile pigment precursors which are usually observed in normal erythrocytes are increased by chemicals such as ascorbic acid and phenylhydrazine HCl, or by preservation, while in the case of anemia by phlebotomies where immature erythrocytes increase, the amount of bile pigment precursors decreases. Consequently, bile pigment precursors in erythrocytes physiologically increase with deterioration.
en-copyright=
kn-copyright=

en-aut-name=NakagawaShoso
en-aut-sei=Nakagawa
en-aut-mei=Shoso
kn-aut-name=’†�ì�¹‘s
kn-aut-sei=’†�ì
kn-aut-mei=�¹‘s
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=72
cd-vols=
no-issue=3
article-no=
start-page=801
end-page=810
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1960
dt-pub=19600228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Epidemiological Observations on Infectious Hepatitis Prevailed in Okayama Prefecture
kn-title=‰ªŽRŒ§‚É‚¨‚¯‚é—¬�s�«ŠÌ‰Š‚Ì—¬�s‚ÉŠÖ‚·‚錟“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=6246 infectious hepatitis cases treated at 25 hospitals located in Okayama Prefecture during the last six years, 1952 to 1957, were studied mainly from the epidemiological point of view, and the following results were obtained. 1) Infectious hepatitis has been prevailed all over the prefecture since the initial epidemic in 1951. As the mode of epidemic became protracted, chronic and abortive forms were prone to increase in number. The ratio of total patients to infectious hepatitis cases was 1.27 per cent. 2) Extensive infections among villagers were noted in 73 hamlets, and it was presumed that the epidemic has been prevailed over the whole prefecture taking a hamlet, village or a town as unit. Infections among family were noted in 62 families, however, fnrther detailed study in the epidemic areas might show the higher morbidity. It was not certain whether these infections were entirely family or simultaneous infections. 3) As to seasonal occurence, considerable number of cases had onset of the disease during the period of early summer to early fall. 4) As to age, it has ranged mostly from the second to third decade, rather many in children but not rare in the aged. As to sex, predominant in males in general, but considerable differences were seen among hospitals and times. No definite relationship was noted between the epidemc and sex. 5) Throughout the last six years there have been 38.7 per cent of chronic hepatitis cases. In 41.3 per cent of the whole patients presented jaundice in their clinical courses. The fact that the longer the period of the epidemic the more increase increase in anicteric cases was noted. 6) Two year's follow-up studies after the epidemic, showed 209 of relapsed cases in whom 36.4 per cent were icteric. 7) 110 cases has jaundice, which was thought to be infectious hepatitis, in the past. Some of them were presumably reinfections or superinfections but definite conclusion could not be made. 8) 20 cases of fulminant hepatitis, malignant type of infectious hepatitis, and 6 cases of protracted form were studied. 22 cases of them were fatal. Such severe hepatitis patients were seen mainly in males of the second and third decades. 9) 61 cases (0.98%) developed postnecrotic cirrhosis, and 10 cases of them were fatal. 10) Serum hepatitis was noted in 1.6 per cent of the whole patients seen in Medical Services at 18 hospitals in Okayama Prefecture during the last six years, 1952 to 1957. No definite correlation between the epidemic of infectious hepatitis and outbreak of serum hepatitis was noted.
en-copyright=
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kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=36
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=37
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=38
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=80
cd-vols=
no-issue=5-6
article-no=
start-page=631
end-page=635
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1968
dt-pub=19680630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Measurement of Human Blood Catalase Activity and the Screening Method of Hypocatalasemia by Spectrophotometry Part 4. A simple method of measuring human blood catalase activity and the screening test for hypocatalasemia
kn-title=•ªŒõŒõ“x–@‚É‚æ‚é�lŒŒ‰tƒJƒ^ƒ‰�[ƒ[Šˆ�«‚Ì’è—Ê‚¨‚æ‚Ñ’áƒJƒ^ƒ‰�[ƒ[ŒŒ‰t�ǂ̃XƒNƒŠ�[ƒjƒ“ƒO–@‚ɂ‚¢‚Ä ‘æ4•Ò –{–@‚É‚æ‚銈�«‚Ì’¼�Ú’è—Ê–@‚Æ’á�uƒJ�vŒŒ�ǂ̃XƒNƒŠ�[ƒjƒ“ƒO–@
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=It is generally accepted that modified Euler-Josephson's method of titration gives the value of catalase activity, �gKcat�h as the standard value. Whereas by the author's method taking the value of catalase activity as "k" measured, for example, at room temperature, recorded on an autorecording apparatus, it will be seen that we get the formula, Kcat=1/1.035 (100/90K+0.513) The present study has led to the following conclusions: This method is characterized by the fact that it is useful for the screening test for hypocatalasemia as well as for simultaneous measurement of the catalase activity in human blood. It is suggested that the level of the screening be fixed more appropriately at 2.4.
Attempts have been made to use a portable UV-colorimeter to the screening but it seemed that this apparatus is not suitable for the purpose.
This method can measure not only the activity of purified catalase but also that of a partially purified catalase. It can also be applied for the measurement of catalase activity in tissues other than blood. It is anticipated that this method can also be useful for the investigation of hypocatalasemic blood catalase from the aspect of enzyme kinetics.
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshito
en-aut-sei=Nakagawa
en-aut-mei=Yoshito
kn-aut-name=’†�ì‰Ã�l
kn-aut-sei=’†�ì
kn-aut-mei=‰Ã�l
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”Œö�O‰q�¶Šw‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=80
cd-vols=
no-issue=5-6
article-no=
start-page=625
end-page=630
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1968
dt-pub=19680630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Measurement of Human Blood Catalase Activity and the Screening Method of Hypocatalasemia by Spectrophotometry Part 3. Evaluation of UV method supplemented with basic experiments on the measurement of human blood catalase activity
kn-title=•ªŒõŒõ“x–@‚É‚æ‚é“üŒŒ‰tƒJƒ^ƒ‰�[ƒ[Šˆ�«‚Ì’è—Ê‚¨‚æ‚Ñ’áƒJƒ^ƒ‰�[ƒ[ŒŒ‰t�ǂ̃XƒNƒŠ�[ƒjƒ“ƒO–@‚ɂ‚¢‚Ä ‘æ3•Ò –{–@‚ÌŒŸ“¢‚ÆŠˆ�«‘ª’è‚ÉŠÖ‚·‚éŠî‘b“IŽÀŒ±
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The present communication deals with the principle of measuring and calculating the catalase activity of human blood by UV method. Under the conditions previously described, it has been clarified that the reaction of catalase-hydrogen peroxide practically follows the first order kinetics within 30-120 seconds. The velocity constant, k, seems to have no concern with the substrate concentration within the range of 0.005-0.025 mole. Catalase values, Kcat, measured under room temperature, are about 10% lower than those taken at 37�Ž. It has been found that measurements of the catalase activity have to be taken within 5 minutes after hemolysis
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshito
en-aut-sei=Nakagawa
en-aut-mei=Yoshito
kn-aut-name=’†�ì‰Ã�l
kn-aut-sei=’†�ì
kn-aut-mei=‰Ã�l
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”Œö�O‰q�¶Šw‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=80
cd-vols=
no-issue=5-6
article-no=
start-page=619
end-page=623
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1968
dt-pub=19680630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Measurement of Human Blood Catalase Activity and the Screening Method of Hypocatalasemia by Spectrophotometry Part 2. Measurement of human blood catalase activity by spectrophotometry with a temperature controlled cell chamber and autorecorder
kn-title=•ªŒõŒõ“xŒv‚É‚æ‚é�lŒŒ‰tƒJƒ^ƒ‰�[ƒ[Šˆ�«‚Ì’è—Ê‚¨‚æ‚Ñ’áƒJƒ^ƒ‰�[ƒ[ŒŒ‰t�ǂ̃XƒNƒŠ�[ƒjƒ“ƒO–@‚ɂ‚¢‚Ä ‘æ2•Ò �P‰·‚È‚ç‚Ñ‚ÉŽ©‹L‹L˜^‘•’u‚ð‘•’…‚µ‚Ä�³�í‹y‚Ñ’á�uƒJ�vŒŒ�ÇŒŒ‰t‚Ì‘ª’è
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshito
en-aut-sei=Nakagawa
en-aut-mei=Yoshito
kn-aut-name=’†�ì‰Ã�l
kn-aut-sei=’†�ì
kn-aut-mei=‰Ã�l
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”Œö�O‰q�¶Šw‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=80
cd-vols=
no-issue=5-6
article-no=
start-page=613
end-page=618
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1968
dt-pub=19680630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the Measurement of Human Blood Catalase Activity and the Screening Method of Hypocatalasemia by Spectrophotometry Part 1. Measurement of Human Blood Catalase Activity by Spectrophotometry (with a Hitachi GPO Model)
kn-title=•ªŒõ�X“x–@‚É‚æ‚é�lŒŒ‰tƒJƒ^ƒ‰�[ƒ[Šˆ�«‚Ì’è—Ê‚¨‚æ‚Ñ’áƒJƒ^ƒ‰�[ƒ[ŒŒ‰t�ǂ̃XƒNƒŠ�[ƒjƒ“ƒO–@‚ɂ‚¢‚Ä ‘æ1•Ò ’¼“ÇŽ®•ªŒõ�X“dŒõ“xŒv‚É‚æ‚é�³�파ƒJƒ^ƒ‰�[ƒ[Šˆ�«‚Ì‘ª’è
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshito
en-aut-sei=Nakagawa
en-aut-mei=Yoshito
kn-aut-name=’†�ì‰Ã�l
kn-aut-sei=’†�ì
kn-aut-mei=‰Ã�l
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”Œö�O‰q�¶Šw‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=88
cd-vols=
no-issue=5-6
article-no=
start-page=363
end-page=371
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1976
dt-pub=19760630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on vectorcardiography Part ‡T. Basic studies on vectorcardiography by Kimura system with special reference to Frank system
kn-title=ƒxƒNƒgƒ‹�S“d�}‚ÉŠÖ‚·‚錤‹† ‘æ‡T•Ò –Ø‘º–@ƒxƒNƒgƒ‹�S“d�}‚ÌŠî‘b“IŒŸ“¢(‚Æ‚­‚ÉFrank–@‚Ƃ̑Δä)
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Using a human torso model which had been made up with reference to normal stature of Japanese adult male and using four types of elliptical cylinder model which have different longitudinal diameter, Kimura system and Frank system were studied from the standpoint of transfer impedeance, and following results were obtained. 1) In Kimura system, elevation of transfer impedance of X and Z leads deviated to upward about 15 degrees in comparison with the latter. Nevertheless, the former's orthogonality was maintained relatively well, and have been scarcely affected by the type of elliptical cylinder. 2) In Frank system, according to narrowing of longitudinal diameter of thorax, orthogonality of X and Z leads became worse and included angles of their transfer impedance became narrow. 3) In Kimura system, the ratio of transfer impedance of X to Y leads was about 1:3 in each model, therefore, frontal plane vectorcardiogram of Kimura system could be useful for diagnosis of cases whose heart-electromotive forces change vertically. 4) Much axis deviation could not be caused by the changes of position of artificial current dipole and longitudinal diameter of the thorax.
en-copyright=
kn-copyright=

en-aut-name=NakagawaMasahiro
en-aut-sei=Nakagawa
en-aut-mei=Masahiro
kn-aut-name=’†�ì‰ë”Ž
kn-aut-sei=’†�ì
kn-aut-mei=‰ë”Ž
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æI“à‰ÈŠw‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=87
cd-vols=
no-issue=9-10
article-no=
start-page=915
end-page=922
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1975
dt-pub=19751030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Experimental Study on Lead Systems of Vectorcardiogram with Canine Homogenious Torso Model
kn-title=Œ¢‚̃xƒNƒgƒ‹�S“d�}—U“±–@‚ÌŠî‘b“IŒŸ“¢�i“`’BƒCƒ“ƒs�[ƒ_ƒ“ƒX‚ÌŠÏ“_‚©‚ç�j
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The transfer impedance determined on Frank's lead system and McFee, Parungao's lead system using canine torso model was studied and following results were obtained. A simplyfied canine torso model was made, which was a cylinderic type imitated faithfully the transverse section in the fifth intercostal space of the canine. The canine which was used as a model has a body weight of 16.2kg. Its torso dimensions were left to right of 14.0cm, front to back of 19.0cm and height of 55.0cm. Its form was an oval on the whole shape with more gently curved surface on the front. Heart center on the dog determined by the X-ray located on the position which was 0.75cm to the left, 2.9cm to the front from the body center in the fifth intercostal soace. The definite dipole was placed on the heart center of the torso filled with 0.1% NaCl solution. Electrode position on the torso surface is defined by two quantities; levels (number 1 throngh 10) and angles in the transverse plane. The levels were separated each other at a distance of 3cm. Thus determined level 6 correspond to heart center level of the canine. The angles were taken each 5 or 10 around the cylinder whose plane passed precisely through the center of the body. Thus, potentials were determined and image surface was drawned on the loops. Image loops were oval and located on left anteriorly and slightly inferiorly from the heart center. As a result, canine image loop was found to be clearly different from the shape of the human's one which has a shape of a pear projecting slightly to the back. Then, normality and orthogonality were examined on the torso with the Frank's orthogonal lead system for human and with the McFee, Parungao's axial lead system for dog resulting the latter to be better than the former.
en-copyright=
kn-copyright=

en-aut-name=FujitaTakashi
en-aut-sei=Fujita
en-aut-mei=Takashi
kn-aut-name=“¡“c‹»
kn-aut-sei=“¡“c
kn-aut-mei=‹»
aut-affil-num=1
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=�Ä“¡‘厡
kn-aut-sei=�Ä“¡
kn-aut-mei=‘厡
aut-affil-num=2
ORCID=

en-aut-name=InoueKatsutoshi
en-aut-sei=Inoue
en-aut-mei=Katsutoshi
kn-aut-name=ˆä�ã�Ÿ–«
kn-aut-sei=ˆä�ã
kn-aut-mei=�Ÿ–«
aut-affil-num=3
ORCID=

en-aut-name=NakagawaMasahiro
en-aut-sei=Nakagawa
en-aut-mei=Masahiro
kn-aut-name=’†�ì‰ë”Ž
kn-aut-sei=’†�ì
kn-aut-mei=‰ë”Ž
aut-affil-num=4
ORCID=

en-aut-name=HiranoKazuhiro
en-aut-sei=Hirano
en-aut-mei=Kazuhiro
kn-aut-name=•½–ì˜a”Ž
kn-aut-sei=•½–ì
kn-aut-mei=˜a”Ž
aut-affil-num=5
ORCID=

en-aut-name=UedaMinoru
en-aut-sei=Ueda
en-aut-mei=Minoru
kn-aut-name=�ã“c–«
kn-aut-sei=�ã“c
kn-aut-mei=–«
aut-affil-num=6
ORCID=

en-aut-name=HisamatsuMitsuo
en-aut-sei=Hisamatsu
en-aut-mei=Mitsuo
kn-aut-name=‹v�¼ŽO�¶
kn-aut-sei=‹v�¼
kn-aut-mei=ŽO�¶
aut-affil-num=7
ORCID=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=Œ´‰ª�ºˆê
kn-aut-sei=Œ´‰ª
kn-aut-mei=�ºˆê
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@’†‰›ŒŸ�¸•”
END

start-ver=1.4
cd-journal=joma
no-vol=90
cd-vols=
no-issue=11-12
article-no=
start-page=1399
end-page=1405
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1978
dt-pub=19781230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of electrode position (I,E,C,A,M) on Frank lead system of vectorcariography
kn-title=ƒxƒNƒgƒ‹�S“d�}�iFrank–@�j‚Ì‹¹•”—U“±Žq�iI,E,C,A,M�j‚̈ʒu‚ÉŠÖ‚·‚錤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The transverse level of electrodes, A, C, E, I and M in Frank system vectorcardiography is important, since it affects the accuracy of the vectorcardiogram. 1. Using a Japanese male torso mode, the effects of shift in electrode position from the fifth to the fourth intercostal space level on lead vector were studied, and results were as follows. The magnitude of elad vector decreased in lead Z and increased in lead Y with moving all electrodes downward from the level of artificial dipole. 2. The transverse level of the center of heart vector was determined in healthy Japanese males in supine position using three-step technique. Following results were obtained. The level was upper than the fifth intercostal space, and in association with an increase in cardio-thoracic ratio, it shifted upward from the fifth intercostal space.
en-copyright=
kn-copyright=

en-aut-name=HaraokaShoichi
en-aut-sei=Haraoka
en-aut-mei=Shoichi
kn-aut-name=Œ´‰ª�ºˆê
kn-aut-sei=Œ´‰ª
kn-aut-mei=�ºˆê
aut-affil-num=1
ORCID=

en-aut-name=NakagawaMasahiro
en-aut-sei=Nakagawa
en-aut-mei=Masahiro
kn-aut-name=’†�ì‰ë”Ž
kn-aut-sei=’†�ì
kn-aut-mei=‰ë”Ž
aut-affil-num=2
ORCID=

en-aut-name=SaitoDaiji
en-aut-sei=Saito
en-aut-mei=Daiji
kn-aut-name=�Ä“¡‘厡
kn-aut-sei=�Ä“¡
kn-aut-mei=‘厡
aut-affil-num=3
ORCID=

en-aut-name=MiyasakaMinoru
en-aut-sei=Miyasaka
en-aut-mei=Minoru
kn-aut-name=‹{�ãŽÀ
kn-aut-sei=‹{�ã
kn-aut-mei=ŽÀ
aut-affil-num=4
ORCID=

en-aut-name=KawasakiTomoko
en-aut-sei=Kawasaki
en-aut-mei=Tomoko
kn-aut-name=�ì�è’qŽq
kn-aut-sei=�ì�è
kn-aut-mei=’qŽq
aut-affil-num=5
ORCID=

en-aut-name=IkenagaToyotake
en-aut-sei=Ikenaga
en-aut-mei=Toyotake
kn-aut-name=�¶’·–LŒ’
kn-aut-sei=�¶’·
kn-aut-mei=–LŒ’
aut-affil-num=6
ORCID=

en-aut-name=YoshiokaNobuhiko
en-aut-sei=Yoshioka
en-aut-mei=Nobuhiko
kn-aut-name=‹g‰ª�M•F
kn-aut-sei=‹g‰ª
kn-aut-mei=�M•F
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=89
cd-vols=
no-issue=9-10
article-no=
start-page=1267
end-page=1283
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1977
dt-pub=19771030
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on vectorcardiography Part II. Vectrocardiographic studies on left axis deviation by comparison of the Frank lead system with Kimura lead system
kn-title=ƒxƒNƒgƒ‹�S“d�}‚ÉŠÖ‚·‚錤‹† ‘æII•Ò Frank–@‚Æ–Ø‘º–@‚̑Δä‚É‚æ‚é�¶Ž²•ÎˆÊ—á‚ÌŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To elucidate the cause of high degree left axis deviation (LAD) revealed in ECG, 86 subjects in total, 60 males and 26 females, whose ECG indicated a QRS-interval less than 0.12 sec and a mean QRS electrical axis in-between -30�Ž to -90�Ž, were selected for analysis of VCG. Lead systems of VCG introduced by Frank and Kimura were employed for this study. As described in preceeding paper, the Kimura lead system is considered to be useful for the analysis of LAD since in experiments of human torso models, this system was demonstrated to have a value in use to detect vertical changes of heart-electromotive-forces. Then, by the analysis of configurations of QRS-loop in the frontal plane of VCG, they were divided as follows; in the Frank lead system: 6 types, F-1 to F-6, in the Kimura lead system: 5 types, CCW(L), CCW(R), CCW(R'), CW(L), CW(R). In the latter, they were furthermore sub-divided into 3 types, a, b, and c, according to the length of the vertical component of QRS-loop. (See the text, Fig. 1 and Fig. 2) Results were as follows: 1) F-4 and F-5 types which are considered to represent the left anterior hemiblock (LAH) in the Frank lead system showed CCW(L) type, left superiorly deviated QRS-loop with elongation, in the Kimura lead system. 2) The S(I) S(II) S(III) type in the ECG was determined to corespond to F-1, F-2, or F-6 type in the Frank lead system, and to CCW(R), CCW(R'), or CW(R) type in the Kimura lead system in which the right component of QRS-loop was dominant. 3) Several cases classified as F-3 or F-6 type in the Frank lead system which could not be defined as LAH were determined as CCW(L)a type in the Kimura lead system suggesting the LAH. 4) There could not be found correlations between Rosenbaum's diagnostic criteria for LAH and these VCG configurations. Therefore, it was suggested by the present study that the analysis of VCG configurations are useful for the diagnosis of LAH. 5) VCGs of ostium primum atrial septal defect were classified as F-6 and CCW(R') types whose configurations of QRS-loop were different from the one of LAH. 6) Several cases of pulmonary emphysema associating with LAD were disclosed to be classified as F-4 and CCW(L)a types suggesting the LAH.
en-copyright=
kn-copyright=

en-aut-name=NakagawaMasahiro
en-aut-sei=Nakagawa
en-aut-mei=Masahiro
kn-aut-name=’†�ì‰ë”Ž
kn-aut-sei=’†�ì
kn-aut-mei=‰ë”Ž
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰È‹³Žº
END

start-ver=1.4
cd-journal=joma
no-vol=98
cd-vols=
no-issue=7-8
article-no=
start-page=687
end-page=695
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1986
dt-pub=19860830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Radiation Therapy of Angioblastoma (Nakagawa) of the Skin
kn-title=ŒŒŠÇ‰è�×–EŽî(’†�ì)‚Ì•úŽË�üŽ¡—Ã
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Percent depth dose curves of Lineac electron beam and Dermopan soft X-ray, which are used for radiation therapy of surface tumors, were studied in 2 patients with angioblastoma (Nakagawa) who had been followed up for a long time after radiation therapy. The results are discussed with a review of the literature. Lineac electron beam therapy at low doses that do not cause remote complications appeared to be useful in the treatment of surface tumors selected after careful consideration of the indications.
en-copyright=
kn-copyright=

en-aut-name=HirakiYoshio
en-aut-sei=Hiraki
en-aut-mei=Yoshio
kn-aut-name=•½–Ø�Ë•v
kn-aut-sei=•½–Ø
kn-aut-mei=�˕v
aut-affil-num=1
ORCID=

en-aut-name=MorimotoSetsuo
en-aut-sei=Morimoto
en-aut-mei=Setsuo
kn-aut-name=�X–{�ß•v
kn-aut-sei=�X–{
kn-aut-mei=�ߕv
aut-affil-num=2
ORCID=

en-aut-name=SatohNobuo
en-aut-sei=Satoh
en-aut-mei=Nobuo
kn-aut-name=�²“¡�L•v
kn-aut-sei=�²“¡
kn-aut-mei=�L•v
aut-affil-num=3
ORCID=

en-aut-name=YamamotoYoshio
en-aut-sei=Yamamoto
en-aut-mei=Yoshio
kn-aut-name=ŽR–{�i—Y
kn-aut-sei=ŽR–{
kn-aut-mei=�i—Y
aut-affil-num=4
ORCID=

en-aut-name=ShirakamiToshiaki
en-aut-sei=Shirakami
en-aut-mei=Toshiaki
kn-aut-name=”’�_•q–¾
kn-aut-sei=”’�_
kn-aut-mei=•q–¾
aut-affil-num=5
ORCID=

en-aut-name=JojaIkuo
en-aut-sei=Joja
en-aut-mei=Ikuo
kn-aut-name=�ãŽÒˆè•v
kn-aut-sei=�ãŽÒ
kn-aut-mei=ˆè•v
aut-affil-num=6
ORCID=

en-aut-name=KimotoShin
en-aut-sei=Kimoto
en-aut-mei=Shin
kn-aut-name=–Ø–{�^
kn-aut-sei=–Ø–{
kn-aut-mei=�^
aut-affil-num=7
ORCID=

en-aut-name=HashimotoKeiji
en-aut-sei=Hashimoto
en-aut-mei=Keiji
kn-aut-name=‹´–{Œ[“ñ
kn-aut-sei=‹´–{
kn-aut-mei=Œ[“ñ
aut-affil-num=8
ORCID=

en-aut-name=AonoKaname
en-aut-sei=Aono
en-aut-mei=Kaname
kn-aut-name=�–ì—v
kn-aut-sei=�–ì
kn-aut-mei=—v
aut-affil-num=9
ORCID=

en-aut-name=NakagiriYoshitada
en-aut-sei=Nakagiri
en-aut-mei=Yoshitada
kn-aut-name=’†‹Ë‹`’‰
kn-aut-sei=’†‹Ë
kn-aut-mei=‹`’‰
aut-affil-num=10
ORCID=

en-aut-name=ArakawaKenzo
en-aut-sei=Arakawa
en-aut-mei=Kenzo
kn-aut-name=�r�쌪ŽO
kn-aut-sei=�r�ì
kn-aut-mei=ŒªŽO
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@’†‰›•úŽË�ü•”

affil-num=11
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•””畆‰ÈŠw‹³Žº
en-keyword=ŒŒŠÇ‰è�×–EŽî(’†�ì)
kn-keyword=ŒŒŠÇ‰è�×–EŽî(’†�ì)
en-keyword=•úŽË�üŽ¡—Ã
kn-keyword=•úŽË�üŽ¡—Ã
en-keyword=“dŽq�üŽ¡—Ã
kn-keyword=“dŽq�üŽ¡—Ã
en-keyword=Dermopan “î X�üŽ¡—Ã
kn-keyword=Dermopan “î X�üŽ¡—Ã
END

start-ver=1.4
cd-journal=joma
no-vol=63
cd-vols=
no-issue=
article-no=
start-page=50
end-page=57
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199206
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=IgEŽó—e‘Ì‚ð‰î‚·‚éŽhŒƒ‚ɑ΂·‚é�D‰–Šî‹…‚ÌŒ`‘Ô“I•Ï‰»‚ÌŒ°”÷‹¾“IŠÏŽ@. �RŒ´‚Æ�RIgEŽhŒƒ‚Ì“Á’¥‚Æ‚»‚Ì‘Šˆá“_
kn-title=Microscopic observation on morphological changes of basophils induced by cross-linking of IgE receptors
en-subtitle=
kn-subtitle=
en-abstract=�RŒ´‚¨‚æ‚Ñ�RIgEŽhŒƒŽž‚Ì�D‰–Šî‹…‚ÌŒ`‘ԕω»‚Ì“Á’¥‚ɂ‚¢‚Ä,ƒqƒXƒ^ƒ~ƒ“—V—£‚Æ‚ÌŠÖ˜A‚Ì‚à‚Æ‚É,Œ°”÷‹¾‰º‚ÉŒoŽž“I‚ÉŠÏŽ@‚µ‚½¡1.�RŒ´ŽhŒƒŽž‚̃qƒXƒ^ƒ~ƒ“—V—£‚Í,15•ªŠÔ‚Ìincubation‚Ì‚¢‚¸‚ê‚ÌŽžŠú‚É‚¨‚¢‚Ä‚à,�RIgEŽhŒƒ‚É”ä‚×—LˆÓ‚É‘½‚­,incubationŽžŠÔ3•ª‚Æ9•ª‚Å‚Í—¼ŽÒŠÔ‚É—LˆÓ‚Ì�·‚ªŒ©‚ç‚ꂽ¡2.�RŒ´ŽhŒƒŽž‚Ì�D‰–Šî‹…�”‚ÌŒ¸�­‚à�RIgEŽhŒƒ‚É”ä‚ׂæ‚è�‚“x‚Å‚ ‚Á‚½¡3.‰^“®˜´�i‚É‚æ‚è—m—œŒ^‚ðŽ¦‚·�R‰–Šî‹…‚Å‚Í,’·Œa/’ZŒa”ä‚Ì‘�‘傪Œ©‚ç‚ꂽ¡‚±‚Ì’·Œa/’ZŒa”ä‚Ì‘�‘å‚ðŽ¦‚·�D‰–Šî‹…‚Í,�RŒ´ŽhŒƒŽž‚É�RIgEŽhŒƒ‚É”ä‚ׂæ‚è�‚•p“x‚ÉŒ©‚ç‚ê,“Á‚Éincubation6•ª‚Æ15•ª‚Å‚Í—¼ŽÒŠÔ‚É—LˆÓ‚Ì�·‚ªŒ©‚ç‚ꂽ¡4.–c‰»Œ^‚ðŽ¦‚·�D‰–Šî‹…‚Å‚Í‚»‚Ì•½‹Ï’¼Œa‚Ì‘�‘傪Œ©‚ç‚ê‚邪,‚±‚Ì•½‹Ï’¼Œa‚Ì‘�‘å‚ɂ‚¢‚Ä‚Í,�RŒ´‚Æ�RlgEŽhŒƒ‚Æ‚ÌŠÔ‚É�·‚ÍŒ©‚ç‚ê‚È‚©‚Á‚½¡ˆÈ�ã‚ÌŒ‹‰Ê‚æ‚è,�RŒ´ŽhŒƒ‚Å‚Í,�D‰–Šî‹…‚Ìactivate,‰^“®˜´�i‚Ö
‚̉ߒö‚ª�RIgEŽhŒƒŽž‚Æ”ä‚ׂæ‚è�‚“x‚Å‚ ‚邪,–c‰»‚ւ̉ߒö‚É‚Í—¼ŽÒŠÔ‚É�·‚ªŒ©‚ç‚ê‚È‚¢‚±‚Æ‚ªŽ¦�´‚³‚ꂽ¡
kn-abstract=Differences in morphological changes of basophils between antigen and anti-IgE�@stimulation were examined in atopic subjects in relation to histamine release.�@1. Antigen-�@induced release of histamine was remarkably more rapid and larger at any incubation time than the release by anit-IgE, and a significant difference was found at 3 to 9 min. 2. Decrease in number of basophils induced by antigen was significantly higher for 12 to 15 min incubation time than that by anti-IgE. 3. Morphological changes of basophils representing increased motility such as an increased ratio of short to long axis diameter (L/S ratio) and an increased incidence of basophils with localized granules (LG) were more often observed in antigen stimulation compared with anti-IgE, and the L/S ratio of the cells was significantly more increased in antigen stimulation at 6 and 15 min. 4. There was no difference in morphological
changes of basophils showimg swollen type (degranulation) such as an increased mean diameter (MD) of the cells between antigen and anti-IgE. These results suggest that antigen activates basophils and induces increased motility more strongly than anti-IgE, but the action on degranulation was not different between the two agents.
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=’J�è�Ÿ˜N
kn-aut-sei=’J�è
kn-aut-mei=�Ÿ˜N
aut-affil-num=1
ORCID=

en-aut-name=NakagawaSaburo
en-aut-sei=Nakagawa
en-aut-mei=Saburo
kn-aut-name=’†�ìŽO˜Y
kn-aut-sei=’†�ì
kn-aut-mei=ŽO˜Y
aut-affil-num=2
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=–Ø‘ºˆè˜Y
kn-aut-sei=ЯԼ
kn-aut-mei=ˆè˜Y
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰È

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰È
en-keyword=Histamine release (ƒqƒXƒ^ƒ~ƒ“—V—£)
kn-keyword=Histamine release (ƒqƒXƒ^ƒ~ƒ“—V—£)
en-keyword=Morphological changes of basophils (�D‰–Šî‹…‚ÌŒ`‘Ô“I•Ï‰»)
kn-keyword=Morphological changes of basophils (�D‰–Šî‹…‚ÌŒ`‘Ô“I•Ï‰»)
en-keyword=Antigen (�RŒ´)
kn-keyword=Antigen (�RŒ´)
en-keyword=Anti-IgE (�RIgE)
kn-keyword=Anti-IgE (�RIgE)
en-keyword=IgE receptors (IgEŽó—e‘Ì)
kn-keyword=IgE receptors (IgEŽó—e‘Ì)
END

start-ver=1.4
cd-journal=joma
no-vol=64
cd-vols=
no-issue=
article-no=
start-page=43
end-page=51
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1993
dt-pub=199306
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=�RŒ´‚¨‚æ‚Ñ Ca ionophore A23187 ŽhŒƒŽž‚É‚¨‚¯‚éƒAƒgƒs�[Œ^‹CŠÇŽxšb‘§––�½ŒŒ�D‰–Šî‹…‚̉^“®”\
kn-title=Difference in motility of basophilic, granulocytes from atopic subjects following antigen- and Ca inophore A23187-stimulation
en-subtitle=
kn-subtitle=
en-abstract=ƒAƒgƒs�[Œ^‹CŠÇŽxšb‘§––�½ŒŒ�D‰–Šî‹…‚ð—p‚¢,�RŒ´‚¨‚æ‚Ñ Ca ionophore A23187 ŽhŒƒŽž‚̃qƒXƒ^ƒ~ƒ“—V—£‚¨‚æ‚Ñ‚»‚ÌŒ`‘Ô“I•Ï‰»‚ɂ‚¢‚Ä”äŠrŒŸ“¢‚µ‚½¡1.�RŒ´ŽhŒƒŽž‚É‚Í, Ca ionophore A23187 ŽhŒƒŽž‚É”ä‚×,�D‰–Šî‹…‚©‚ç‚̃qƒXƒ^ƒ~ƒ“—V—£‚¨‚æ‚Ñ�D‰–Šî‹…�”‚ÌŒ¸�­‚Ì’ö“x‚Í,‚æ‚è‹}Œƒ‚Å‚©‚Â�‚“x‚Å‚ ‚Á‚½¡2.�D‰–Šî‹…‚ÌŒ`‘Ô“I•Ï‰»,‚·‚È‚í‚¿,’·Œo/’ZŒo”ä‚Ì‘�‘å,ŒÀ‹Ç�«è÷—±‚ ‚é‚¢‚Í‹U‘«‚ð—L‚·‚é�D‰–Šî‹…‚Ì�oŒ»•p“x‚Ì‘�‰Á‚Ȃǂ̉^“®”\‚̘´�i‚ðŽ¦�´‚·‚é�D‰–Šî‹…‚ÌŒ`‘Ô“I•Ï‰»‚Í, Ca ionophore A23187 ‚É”ä‚×�RŒ´ŽhŒƒŽž‚É‚æ‚è�‚“x‚Å‚ ‚Á‚½¡ˆê•û,•½‹Ï’¼Œa‚Ì‘�‘å,5ŒÂˆÈ�ã‚Ì‹ó–C‚ð—L‚·‚é�D‰–Šî‹…‚Ì�oŒ»•p“x‚Ì‘�‰Á‚È‚Ç‚Ì,‚Þ‚µ‚ë–c‰»ŒXŒü‚ðŽ¦�´‚·‚é�D‰–Šî‹…‚ÌŒ`‘Ô“I•Ï‰»‚Í,�RŒ´ŽhŒƒŽž‚É”ä‚×, Co ionophore A23187 ŽhŒƒŽž‚É‚æ‚è�‚“x‚Å‚ ‚Á‚½¡‚±‚ê‚ç‚ÌŒ‹‰Ê‚æ‚è,�RŒ´ŽhŒƒ‚É‚æ‚éIgEŽó—e‘Ì‚Ìbridging‚ª,�D‰–Šî‹…‚ðŠˆ�«‰»‚µ,‰^“®”\‚̘´�i‚ð‚Ђ«‹N‚±‚·‚à‚Ì‚Æ”»’f‚³‚ꂽ�B
kn-abstract=We examined histamine release and morphological changes in basophilic granulocytes from atopic subjects, in response to stimulation with antigen and Ca ionophore A23187. 1. Histamine release and a reduction in the rumber of basophils were more rapid and greater in extent at an early stage of antigen stimulation compared with Ca ionophore A23187 stimulation. 2. Morphological changes in basophils, represented by increased motility, in terms of an increased ratio of short to long axis diameter (L/S ratio), as well as the increased frequency of basophils with localized granules and those with pseudopods, were more often observed antigen stimulation than with Ca ionophore A23187 stimulation. In contrast, morphogical changes in which basophils appeared swollen, showing an increased mean cell diameter and an increased frequency of cells with 5 vacuoles or more were more predominant with Ca ionophore A23187 than with antigen stimulation. The results obtained here show that bridging of IgE receptors is essential to activate basophils and induce increased motility in these cells.
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=’J�è�Ÿ˜N
kn-aut-sei=’J�è
kn-aut-mei=�Ÿ˜N
aut-affil-num=1
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=‹M’JŒõ
kn-aut-sei=‹M’J
kn-aut-mei=Λ
aut-affil-num=2
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=Œä‘D�®Žu
kn-aut-sei=Œä‘D
kn-aut-mei=�®Žu
aut-affil-num=3
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=Œõ‰„•¶—T
kn-aut-sei=Œõ‰„
kn-aut-mei=•¶—T
aut-affil-num=4
ORCID=

en-aut-name=OchiKoji
en-aut-sei=Ochi
en-aut-mei=Koji
kn-aut-name=‰z’q�_“ñ
kn-aut-sei=‰z’q
kn-aut-mei=�_“ñ
aut-affil-num=5
ORCID=

en-aut-name=HaradaHideo
en-aut-sei=Harada
en-aut-mei=Hideo
kn-aut-name=Œ´“c‰p—Y
kn-aut-sei=Œ´“c
kn-aut-mei=‰p—Y
aut-affil-num=6
ORCID=

en-aut-name=NakagawaSaburo
en-aut-sei=Nakagawa
en-aut-mei=Saburo
kn-aut-name=’†�ì“ñ˜Y
kn-aut-sei=’†�ì
kn-aut-mei=“ñ˜Y
aut-affil-num=7
ORCID=

en-aut-name=SodaRyo
en-aut-sei=Soda
en-aut-mei=Ryo
kn-aut-name=�@“c—Ç
kn-aut-sei=�@“c
kn-aut-mei=—Ç
aut-affil-num=8
ORCID=

en-aut-name=TakahashiKiyoshi
en-aut-sei=Takahashi
en-aut-mei=Kiyoshi
kn-aut-name=�‚‹´�´
kn-aut-sei=�‚‹´
kn-aut-mei=�´
aut-affil-num=9
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=–Ø‘ºˆè˜Y
kn-aut-sei=ЯԼ
kn-aut-mei=ˆè˜Y
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”—Õ�°ŒŸ�¸ˆãŠw

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”—Õ�°ŒŸ�¸ˆãŠw

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ2“à‰È

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ2“à‰È

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ2“à‰È

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ2“à‰È
en-keyword=histamine release (ƒqƒXƒ^ƒ~ƒ“—V—£)
kn-keyword=histamine release (ƒqƒXƒ^ƒ~ƒ“—V—£)
en-keyword=increased basophil motility (�D‰–Šî‹…‚̉^“®”\‚̘´�i)
kn-keyword=increased basophil motility (�D‰–Šî‹…‚̉^“®”\‚̘´�i)
en-keyword=bridging of IgE receptors (LgE Žó—e‘Ì)
kn-keyword=bridging of IgE receptors (LgE Žó—e‘Ì)
en-keyword=antigen (�RŒ´)
kn-keyword=antigen (�RŒ´)
en-keyword=Ca ionophore A23187
kn-keyword=Ca ionophore A23187
END

start-ver=1.4
cd-journal=joma
no-vol=8
cd-vols=
no-issue=1
article-no=
start-page=37
end-page=42
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970910
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Influence of the Bone for Electron-beam Therapy
kn-title=“dŽq�üŽ¡—Âɂ¨‚¯‚é�œ‚Ì�ü—Ê•ª•z‚ɑ΂·‚é‰e‹¿‚ÉŠÖ‚·‚錟“¢
en-subtitle=
kn-subtitle=
en-abstract=The Electron-beam therapy is often used for the treatment to malignant tumors on the surface or its neighborhood of the body. An electron-beam has the range depended on its energy, and its dose is rapidly decreased at the points beyond the range. This property is available to irradiating
a tumor with leaving the critical organs unexposed. However, we should take notice that the dose-distributions are disordered if materials of various densities are in the irradiation field. In this paper, we examined how the dose-distribution are disordered by using the phantom made from human bones of various volumes. As a result, the peculiar disorders of the dose-distribution due to the difference of the bone width were found at the back and edge of a bone. Moreover, the dose at the edge of a bone was decreased, but the dose at the side of a bone was rapidly increased in the distance position from the bone. It is necessary to take account of that the above peculiar phenomenon affect the total dose for the treatment when bones exist near the target volume in the irradiation field.
kn-abstract=“dŽq�üŽ¡—ÂÍ,‘Ì•\–Ê‚Ü‚½‚Í‚»‚Ì‹ß–T‚É”­�¶‚·‚鈫�«Žîᇂ̎¡—Âɂµ‚΂µ‚Ηp‚¢‚ç‚ê‚鎡—Ö@‚Å‚ ‚é¡“dŽq�ü‚̓Gƒlƒ‹ƒM�[‚ɑΉž‚µ‚½”ò’ö‚ðŽ�‚Á‚Ä‚¨‚è,”ò’ö‚ð‰z‚¦‚é‚Æ‹}Œƒ‚É�ü—Ê‚ÍŒ¸�­‚·‚é�B‚±‚Ì�«Ž¿‚ÍŽîᇂɈê’è‚Ì�ü—Ê‚ð�ÆŽË‚µ,Žîᇌã•û‚É‘¶�Ý‚·‚錈’è‘ŸŠí‚ð•ÛŒì‚·‚邱‚Æ‚ª‚Å‚«‚é‚Ì‚Å,•a‘ƒ‚ð‘I‘ð“I
‚ÉŽ¡—·‚é‚Ì‚É�D“s�‡‚Å‚ ‚é¡‚µ‚©‚µ,�ÆŽË–ì“à‚É�l‘Ì‹O•”‘g�D‚æ‚è–§“x‚̈Ⴄ•¨Ž¿‚ª‘¶�Ý‚·‚é�ê�‡,ŽU—�,‹zŽû‚̉e‹¿‚ª‘å‚«‚­,“dŽq�ü�ü—Ê•ª•z‚Í—�‚ꂽ‚à‚Ì‚Æ‚È‚é¡�¡‰ñ,�l‘Ì“à‚É‚ ‚é�œ‚ð‘z’肵‚ÄVolume‚̈Ⴄ�œPhantom‚ðŽg
—p‚µ‚ĉe‹¿‚𒲂ׂ½‚Æ‚±‚ë,�œ•�‚É‚æ‚Á‚Ä�œŒã•û‚¨‚æ‚Ñ’f’[‚É�ü—Ê‚Ì—�‚ꂪ�¶‚¶‚邱‚Æ‚ª‚í‚©‚Á‚½¡‚·‚È‚í‚¿,�œ‚Ì’†‰›‚Å‚Í‚ ‚é’ö“xŒã•û‚É‹——£‚ª—£‚ê‚é‚Æ,�ü—Ê‚Í‘å‚«‚­Œ¸�­‚·‚錻�Û‚ªŒ©‚ç‚ꂽ�B‚Ü‚½,‰¡•ûŒü‚Ì�ü—Ê•ª•z‚Í�œ’f’[‹ß‚­‚ňê’U�ü—Ê‚ÌŒ¸�­‚ªŒ©‚ç‚ê,’f’[‚𗣂ê‚é‚Æ‹}Œƒ‚É‘�‰Á‚·‚é¡‚µ‚½‚ª‚Á‚Ä,ŽÀ�Û‚Ì—Õ�°‚É‚¨‚¢‚Ä,Target Volume‹ß‚­‚É�œ‚ª‘¶�Ý‚·‚é�ê�‡‚Í‘��ü—Ê‚ÌŒˆ’è‚É�Û‚µ‚Ä’�ˆÓ‚ª•K—v‚Å‚ ‚é¡
en-copyright=
kn-copyright=

en-aut-name=NakagiriYoshitada
en-aut-sei=Nakagiri
en-aut-mei=Yoshitada
kn-aut-name=’†‹Ë‹`’‰
kn-aut-sei=’†‹Ë
kn-aut-mei=‹`’‰
aut-affil-num=1
ORCID=

en-aut-name=InamuraKeiji
en-aut-sei=Inamura
en-aut-mei=Keiji
kn-aut-name=ˆî‘ºŒ\Ži
kn-aut-sei=ˆî‘º
kn-aut-mei=Œ\Ži
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ORCID=

en-aut-name=TaharaSeiji
en-aut-sei=Tahara
en-aut-mei=Seiji
kn-aut-name=“cŒ´�½Ži
kn-aut-sei=“cŒ´
kn-aut-mei=�½Ži
aut-affil-num=3
ORCID=

en-aut-name=UnoHirofumi
en-aut-sei=Uno
en-aut-mei=Hirofumi
kn-aut-name=‰F–ì�O•¶
kn-aut-sei=‰F–ì
kn-aut-mei=�O•¶
aut-affil-num=4
ORCID=

en-aut-name=AzumaYoshiharu
en-aut-sei=Azuma
en-aut-mei=Yoshiharu
kn-aut-name=“Œ‹`�°
kn-aut-sei=“Œ
kn-aut-mei=‹`�°
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en-aut-name=SibuyaKoichi
en-aut-sei=Sibuya
en-aut-mei=Koichi
kn-aut-name=�a’JŒõˆê
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kn-aut-mei=Œõˆê
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ORCID=

en-aut-name=GotoSachiko
en-aut-sei=Goto
en-aut-mei=Sachiko
kn-aut-name=Œã“¡�²’mŽq
kn-aut-sei=Œã“¡
kn-aut-mei=�²’mŽq
aut-affil-num=7
ORCID=

en-aut-name=MaruyamaToshinori
en-aut-sei=Maruyama
en-aut-mei=Toshinori
kn-aut-name=ŠÛŽR•q‘¥
kn-aut-sei=ŠÛŽR
kn-aut-mei=•q‘¥
aut-affil-num=8
ORCID=

en-aut-name=MoriokaYasuki
en-aut-sei=Morioka
en-aut-mei=Yasuki
kn-aut-name=�X‰ª‘׎÷
kn-aut-sei=�X‰ª
kn-aut-mei=‘׎÷
aut-affil-num=9
ORCID=

en-aut-name=SakaeKatsuyosi
en-aut-sei=Sakae
en-aut-mei=Katsuyosi
kn-aut-name=‰h�Ÿ”ü
kn-aut-sei=‰h
kn-aut-mei=�Ÿ”ü
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ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=’†�ì•x•v
kn-aut-sei=’†�ì
kn-aut-mei=•x•v
aut-affil-num=11
ORCID=

en-aut-name=TakemotoMitsuhiro
en-aut-sei=Takemoto
en-aut-mei=Mitsuhiro
kn-aut-name=•�–{�[�L
kn-aut-sei=•�–{
kn-aut-mei=�[�L
aut-affil-num=12
ORCID=

en-aut-name=SugitaKatsuhiko
en-aut-sei=Sugita
en-aut-mei=Katsuhiko
kn-aut-name=�™“c�Ÿ•F
kn-aut-sei=�™“c
kn-aut-mei=�Ÿ•F
aut-affil-num=13
ORCID=

en-aut-name=HirakiYoshio
en-aut-sei=Hiraki
en-aut-mei=Yoshio
kn-aut-name=•½–Ø�Ë•v
kn-aut-sei=•½–Ø
kn-aut-mei=�˕v
aut-affil-num=14
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@’†‰›•úŽË�ü•”

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@’†‰›•úŽË�ü•”

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@’†‰›•úŽË�ü•”

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@’†‰›•úŽË�ü•”

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=11
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=12
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=13
en-affil=
kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”

affil-num=14
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº
en-keyword=“dŽq�üŽ¡—à (electron-beam therapy)
kn-keyword=“dŽq�üŽ¡—à (electron-beam therapy)
en-keyword=�ü—Ê•ª•z (dose distribution)
kn-keyword=�ü—Ê•ª•z (dose distribution)
en-keyword=•s‹ÏŽ¿•¨Ž¿ (inhomogeneity)
kn-keyword=•s‹ÏŽ¿•¨Ž¿ (inhomogeneity)
END

start-ver=1.4
cd-journal=joma
no-vol=121
cd-vols=
no-issue=1
article-no=
start-page=17
end-page=24
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2009
dt-pub=20090401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Two cases of mandibular and masticatory reconstruction with vascularized fibra bone flaps and implants
kn-title=ŒŒŠÇ•¿•täC�œ”ç•ÙˆÚ�A‚ƃCƒ“ƒvƒ‰ƒ“ƒg‚É‚æ‚éŠ{�œ™ù�‡�ÄŒš‚Ì‚Q—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=�@Defects of the jawbone have conventionally been repaired using free bone grafts and metallic plates, but patients undergoing reconstruction using these materials experience difficulty using dentures and restoring masticatory function. The use of vascularized bone grafts, which has recently been enabled, has improved bone graft survival rates, and its combination with dental implants has enabled both morphological and functional reconstruction, leading to a higher quality of life.
�@We experienced two patients with tumors of the jaw that were treated by resecting and reconstructing it using a vascularized bone graft with the cooperation of the Department of Plastic Surgery in the School of Medicine. We subsequently inserted dental implants, and the superstructure was created by the Department of Prosthetics. We report the course of these patients, who achieved sufficient jaw morphology as well as masticatory function and who are presently satisfied overall three years to three years and nine months postoperatively.
en-copyright=
kn-copyright=

en-aut-name=TakagiShin
en-aut-sei=Takagi
en-aut-mei=Shin
kn-aut-name=�‚–ØœÄ
kn-aut-sei=�‚–Ø
kn-aut-mei=π
aut-affil-num=1
ORCID=

en-aut-name=MizukawaNobuyoshi
en-aut-sei=Mizukawa
en-aut-mei=Nobuyoshi
kn-aut-name=�…�ì“W‹g
kn-aut-sei=�…�ì
kn-aut-mei=“W‹g
aut-affil-num=2
ORCID=

en-aut-name=FukunagaJoji
en-aut-sei=Fukunaga
en-aut-mei=Joji
kn-aut-name=•Ÿ‰i�éŽi
kn-aut-sei=•Ÿ‰i
kn-aut-mei=�éŽi
aut-affil-num=3
ORCID=

en-aut-name=IshidaNobuhisa
en-aut-sei=Ishida
en-aut-mei=Nobuhisa
kn-aut-name=�Γc“W‹v
kn-aut-sei=�Γc
kn-aut-mei=“W‹v
aut-affil-num=4
ORCID=

en-aut-name=MaruoYukinori
en-aut-sei=Maruo
en-aut-mei=Yukinori
kn-aut-name=ŠÛ”ö�KŒ›
kn-aut-sei=ŠÛ”ö
kn-aut-mei=�KŒ›
aut-affil-num=5
ORCID=

en-aut-name=KannyamaManabu
en-aut-sei=Kannyama
en-aut-mei=Manabu
kn-aut-name=Š®ŽRŠw
kn-aut-sei=Š®ŽR
kn-aut-mei=Šw
aut-affil-num=6
ORCID=

en-aut-name=KimataYoshihiro
en-aut-sei=Kimata
en-aut-mei=Yoshihiro
kn-aut-name=–،Ҍ[—T
kn-aut-sei=–ØŒÒ
kn-aut-mei=Œ[—T
aut-affil-num=7
ORCID=

en-aut-name=KoushimaIsao
en-aut-sei=Koushima
en-aut-mei=Isao
kn-aut-name=Œõ“ˆŒM
kn-aut-sei=Œõ“ˆ
kn-aut-mei=ŒM
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–ò‘��‡Œ¤‹†‰È�@Š{Œû�o�ÄŒšŠO‰ÈŠw

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•Šw•”•�‘®•a‰@�@Œû�oŠO‰È�i�ÄŒšŒn�j

affil-num=3
en-affil=
kn-affil=•P˜HŽs

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•Šw•”•�‘®•a‰@�@Œû�oŠO‰È�i�ÄŒšŒn�j

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–ò‘��‡Œ¤‹†‰È�@™ù�‡�E—L�°‹`Ž••â’ÔŠw

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–ò‘��‡Œ¤‹†‰È�@ƒCƒ“ƒvƒ‰ƒ“ƒg�Ä�¶•â’ÔŠw

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–ò‘��‡Œ¤‹†‰È�@Œ`�¬�ÄŒšŠO‰ÈŠw

affil-num=8
en-affil=
kn-affil=“Œ‹ž‘åŠw‘åŠw‰@ˆãŠwŒnŒ¤‹†‰È�@Š´Šo�E‰^“®‹@”\ˆãŠw
en-keyword=ŒŒŠÇ•¿•t�œˆÚ�A�@�ivascularized bone graft�j
kn-keyword=ŒŒŠÇ•¿•t�œˆÚ�A�@�ivascularized bone graft�j
en-keyword=Š{�œ�ÄŒš�@�imandibular reconstruction�j
kn-keyword=Š{�œ�ÄŒš�@�imandibular reconstruction�j
en-keyword=ƒCƒ“ƒvƒ‰ƒ“ƒg�@�iimplant�j
kn-keyword=ƒCƒ“ƒvƒ‰ƒ“ƒg�@�iimplant�j
en-keyword=™ù�‡�ÄŒš�@�iocclusal reconstruction�j
kn-keyword=™ù�‡�ÄŒš�@�iocclusal reconstruction�j
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=11-12
article-no=
start-page=1287
end-page=1299
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=1991
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Nutritional effects of branched chain amino acids and lipids in surgical stress after partial hepatectomy in the rat
kn-title=�‚”Z“x•ªŠò�½ƒAƒ~ƒmŽ_‚ð’‚‘fŒ¹‚Æ‚·‚é�¬•ª‰h—{�Ü‚Ì�N�P‰º‚É‚¨‚¯‚éŒø‰Ê�\ŠÌ�Ø�œƒ‰ƒbƒg‚ð—p‚¢‚Ä�\
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The nutritional influence of branched chain amino acids (BCAA) and lipids in surgical stress was examined after 70% hepatectomy in rats. Two types of elemental diet (ED) were given through the gastrostomy tude for 7 days. Group A : ED containing 33% BCAA and 30% lipid (medium chain triglycerides 8.5g�{soy bean oil 1.5g/300 kcal). Group B : ED containing 17% BCAA and 1.5% lipid (soy bean oil 0.49g/300 kcal). Up to the 7th postoperative day, the excretion of nitrogen into urine decreased in group A, but no change occurred in group B. Up to the 5th postoperative day, molar ratio of 3MH to creatinine in urine in group A decreased more rapidly than in group B. Plasma concentration of albumin in group A was higher than in group B on the 7th postoperative day. Fischer ratio was significantly higher in group A than in group B on the 7th postoperative day. Both plasma and muscle levels of Tyr, Met and Gln were higher in group B than in group A, Glu and Ala were lower in group B than in group A. Essential fatty acid deficiency occurred more severely in group B than in group A. While fatty livers were microscopically observed in some livers in group B, there were few fatty deposits in group A.
en-copyright=
kn-copyright=

en-aut-name=MizutaMinoru
en-aut-sei=Mizuta
en-aut-mei=Minoru
kn-aut-name=�…“c–«
kn-aut-sei=�…“c
kn-aut-mei=–«
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñŠO‰ÈŠw‹³Žº
en-keyword=•ªŠò�½ƒAƒ~ƒmŽ_
kn-keyword=•ªŠò�½ƒAƒ~ƒmŽ_
en-keyword=Ž‰–b“û�Ü
kn-keyword=Ž‰–b“û�Ü
en-keyword=Œo’°‰h—{
kn-keyword=Œo’°‰h—{
en-keyword=Ž‰–bŠÌ
kn-keyword=Ž‰–bŠÌ
END

start-ver=1.4
cd-journal=joma
no-vol=102
cd-vols=
no-issue=1-2
article-no=
start-page=165
end-page=176
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199002
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Magnetic resonance image database system and its clinical applications
kn-title=MR ‰æ‘œƒf�[ƒ^ƒx�[ƒXƒVƒXƒeƒ€‚ÌŠJ”­‚Æ‚»‚Ì—Õ�°‰ž—p‚ÉŠÖ‚·‚錤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A magnetic resonance (MR) image detabase system has been developed. The purpose of this paper is to present this system and its application. It consists of an image processing system and database system to handle data of clinical cases and a medical knowledge base. Using the image processing system and the database system with stored data of clinical cases, the MR image data of cases can be retrieved by diagnosis as well as ID number, patient's name, etc., and MR images can be processed. By using the database system with the medical knowledge base, differential diagnoses can be offered.
en-copyright=
kn-copyright=

en-aut-name=NoriyasuToshiaki
en-aut-sei=Noriyasu
en-aut-mei=Toshiaki
kn-aut-name=‘¥ˆÀ�r�º
kn-aut-sei=‘¥ˆÀ
kn-aut-mei=�r�º
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº
en-keyword=MRI
kn-keyword=MRI
en-keyword=database
kn-keyword=database
en-keyword=medical image
kn-keyword=medical image
en-keyword=knowledge base
kn-keyword=knowledge base
en-keyword=PACS
kn-keyword=PACS
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=4
article-no=
start-page=247
end-page=255
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=1991
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Oncogene mRNA in gastric cancer by in situ hybridization by using a biotin-labeled probe
kn-title=Biotin •WŽ¯ probe ‚ð—p‚¢‚½ histo in situ hydridization –@‚É‚æ‚éˆÝŠà‘g�D‚É‚¨‚¯‚éŠàˆâ“`Žq mRNA ‚ÌŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Expression of oncogene mRNA in gastric cancer was studied by in situ hybridization. Cancer tissues were fixed in formalin and embeded in paraffin. Then, DNA-mRNA hybridization was performed by using two biotin-labeled cDNA probes (c-myc, c-Ha ras).
Oncogene mRNA was intracuelularly localized, mainly in the cytoplasm, and also found in the nucleus of partial cells. Higher concentrations of oncogene mRNA vere found in advanced cancers than in early cancers, and in metastatic positive cases of the above n2 than of n0 or n1.
This suggests that the expression of oncogene mRNA is related to the malignant potency of cancer.
en-copyright=
kn-copyright=

en-aut-name=TanakaIzuru
en-aut-sei=Tanaka
en-aut-mei=Izuru
kn-aut-name=“c’†�o
kn-aut-sei=“c’†
kn-aut-mei=�o
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº
en-keyword=histo in situ hybridization –@
kn-keyword=histo in situ hybridization –@
en-keyword=ˆÝŠà
kn-keyword=ˆÝŠà
en-keyword=Šàˆâ“`Žq
kn-keyword=Šàˆâ“`Žq
en-keyword=‚�RNA
kn-keyword=‚�RNA
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=1-2
article-no=
start-page=183
end-page=197
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=1991
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Experimental study on pathogenesis and treatment of cerebral vasospasm Part 2. Effects of PGI2 analogue, thromboxane A2 synthetase inhibitor and Ca blocker on experimental delayed spasm models
kn-title=”]ŒŒŠÇ�¹�k‚Ì”­�¶‹@�˜‚ÆŽ¡—ÂɊւ·‚éŽÀŒ±“IŒ¤‹† ‘æ2•Ò ŽÀŒ±“I’x”­�«”]ŒŒŠÇ�¹�k‚ɑ΂·‚é PGI2 analogue, Thromboxane A2 �‡�¬�y‘f‘jŠQ�Ü, Ca �h�R�Ü‚ÌŒø‰Ê
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The effects of a PGI2 analogue (OP-41483), a thromboxane A2 synthetase inhibitor (OKY-046) and a Ca blocker (nifedipine) on the diameter of constricted basilar arteries and on the regional cerebral blood flow (r-CBF) in the brain stem were investigated in the cat delayed spasm model. The experiment was performed three days (72 hours) after artificial subarachnoid hemorrhage. The basilar artery was exposed transclivally, and more advanced vasospasm was produced by topical application of a lysed erythrocyte solution for 5 to 6 hours which domonstrated no more vascular dilatation even by topical application of papaverine hydrochloride (0.01mg/ml). In the delayed spasm model, the intravenous administration of neither OP-41483 (8ƒÊg/kg), OKY-046 (60mg/kg) nor nifedipine (0.003mg/kg) affected the vascular diameter. OP-41483 increased r-CBF in the brain stem in 3, and nifedipine increased it in 4 out of the 5 studied delayed spasm models, whereas OKY-046 never increased r-CBF (n=5). There was no significant difference in the amount of fatty acids including arachidonic acid between normal and constricted arteries. This study suggested that thromboxane A2 is not the major factor of cerebral vasospasm and OKY-046 might not be effective on vascular diameter or r-CBF at the late spasm stage. However, the PGI2 analogue (OP-41483) and Ca blocker (nifedipine) may be effective in increasing r-CBF even at the late spasm stage.
en-copyright=
kn-copyright=

en-aut-name=MotokiMototsugu
en-aut-sei=Motoki
en-aut-mei=Mototsugu
kn-aut-name=Œ³–ØŠîŽk
kn-aut-sei=Œ³–Ø
kn-aut-mei=ŠîŽk
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•””]�_ŒoŠO‰È‹³Žº
en-keyword=cerebral vasospasm
kn-keyword=cerebral vasospasm
en-keyword=thromboxane A2
kn-keyword=thromboxane A2
en-keyword=OP-41483
kn-keyword=OP-41483
en-keyword=OKY-046
kn-keyword=OKY-046
en-keyword=nifedipine
kn-keyword=nifedipine
END

start-ver=1.4
cd-journal=joma
no-vol=62
cd-vols=
no-issue=
article-no=
start-page=47
end-page=51
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=199108
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Motility of basophilic granulocytes and histaminerelease
kn-title=�D‰–Šî‹…‚̉^“®”\‚ƃqƒXƒ^ƒ~ƒ“—V—£
en-subtitle=
kn-subtitle=
en-abstract=Morphological changes of basophilic leucocytes from atopic asthmatics were observed in relation to histamine release after the cells were challeuged by a specific allergen, anti-IgE and Ca ionophore A 23187 . 1. Increase in motility and degranulation of basophilic granulocytes were observed after the stimulation with antigen and anti-IgE.
The incidence of basophils with oriented movement was siguificantly increased at 36 min and reached the peak at 12-15 min after addition of antigen. 2. A decreased
number of basophils, increased cell diameter and increased ratio of the short to long axis diameters were observed with a significant amount of histamine release after
antigen and anti-IgE stimulation. 3. Compared to cell reactions to antigen and anti-IgE, Ca ionophore A 23187 stimulation showed more decreased motility and greater
increase in the diameter of the cells.
kn-abstract=ŠeŽíŽhŒƒ•¨Ž¿“Y‰ÁŽž‚Ì�D‰–Šî‹…‚ÌŒ`‘Ô“I•Ï‰»�\‰^“®˜´�i‚Æ–c‰»�C’Eè÷—±�\‚Ɖ»Šw“`’B•¨Ž¿—V—£‚Æ‚ÌŠÖ˜A‚ð’†�S‚Ɏ኱‚Ì’mŒ©‚ð‚ׂ̂½�B‚Ü‚¸�C�RŒ´ŽhŒƒŽž‚É‚Í�C(1)‰^“®˜´�i‚ð‚«‚½‚µ�C—m—œ�ó‚ðŽ¦‚·�D‰–Šî‹…‚Æ–c‰»�C’Eè÷—±‚ðŽ¦‚·�D‰–Šî‹…‚Ì2Ží—Þ‚ªŠÏŽ@‚³‚ê‚邱‚Æ�C(2)ƒAƒgƒs�[Œ^šb‘§‚Ì�D‰–Šî‹…‚ÍŒ’�N�l‚Æ”ä‚ׂđS”Ê“I‚ɉ^“®‚ª—}�§‚³‚ê‚Ä‚¢‚邱‚Æ�C(3)‰^“®˜´�i‚Ì�ó‘Ô‚Æ‚µ‚Ä‚Í�Crandom movement‚Æoriented movement‚ª‚ ‚è�C�RŒ´‚ɑΉž‚µ‚½“Á’¥“I‚ȉ^“®˜´�i‚Íoriented movement‚Å‚ ‚邱‚Æ�C(4)‰^“®˜´�i‚Æ–c‰»�C’Eè÷—±‚Í�C˜A‘±‚µ‚½ˆê˜A‚Ì‚à‚Ì‚Å‚Í‚È‚­�C‚»‚ꂼ‚ê“Æ—§‚µ‚½‰ß’ö‚ðŽ�‚Á‚Ä‚¢‚邱‚Æ�C‚È‚Ç‚ªŠÏŽ@‚³‚ê‚Ä‚¢‚é�B‚Ü‚½�CŽhŒƒ•¨Ž¿‚ÌŽí—Þ‚É‚æ‚Á‚Ä�C�D‰–Šî‹…‚ÌŒ`‘Ô“I•Ï‰»‚≻Šw“`’B•¨Ž¿—V—£‚Ì�ó‘Ô‚ªˆÙ‚Ȃ邱‚Ƃɂ‚¢‚Ä‚à•ñ��‚µ‚½�B
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=’J�è�Ÿ˜N
kn-aut-sei=’J�è
kn-aut-mei=�Ÿ˜N
aut-affil-num=1
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=‹M’JŒõ
kn-aut-sei=‹M’J
kn-aut-mei=Λ
aut-affil-num=2
ORCID=

en-aut-name=OkazakiMorihiro
en-aut-sei=Okazaki
en-aut-mei=Morihiro
kn-aut-name=‰ª�èŽç�G
kn-aut-sei=‰ª�è
kn-aut-mei=Žç�G
aut-affil-num=3
ORCID=

en-aut-name=MifuneTakashi
en-aut-sei=Mifune
en-aut-mei=Takashi
kn-aut-name=Œäät�®Žu
kn-aut-sei=Œäät
kn-aut-mei=�®Žu
aut-affil-num=4
ORCID=

en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=Œõ‰„•¶—T
kn-aut-sei=Œõ‰„
kn-aut-mei=•¶—T
aut-affil-num=5
ORCID=

en-aut-name=NakagawaSaburo
en-aut-sei=Nakagawa
en-aut-mei=Saburo
kn-aut-name=’†�ìŽO˜Y
kn-aut-sei=’†�ì
kn-aut-mei=ŽO˜Y
aut-affil-num=6
ORCID=

en-aut-name=SodaRyo
en-aut-sei=Soda
en-aut-mei=Ryo
kn-aut-name=�@“c—Ç
kn-aut-sei=�@“c
kn-aut-mei=—Ç
aut-affil-num=7
ORCID=

en-aut-name=TadaShinya
en-aut-sei=Tada
en-aut-mei=Shinya
kn-aut-name=‘½“c�T–ç
kn-aut-sei=‘½“c
kn-aut-mei=�T–ç
aut-affil-num=8
ORCID=

en-aut-name=TakahashiKiyoshi
en-aut-sei=Takahashi
en-aut-mei=Kiyoshi
kn-aut-name=�‚‹´�´
kn-aut-sei=�‚‹´
kn-aut-mei=�´
aut-affil-num=9
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=–Ø‘ºˆè˜Y
kn-aut-sei=ЯԼ
kn-aut-mei=ˆè˜Y
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@ŽO’©•ª‰@“à‰È

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@‘æ“ñ“à‰È

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@‘æ“ñ“à‰È

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@‘æ“ñ“à‰È

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@‘æ“ñ“à‰È

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•�‘®•a‰@‘æ“ñ“à‰È
en-keyword=�D‰–Šî‹… (Basophils)
kn-keyword=�D‰–Šî‹… (Basophils)
en-keyword=�RŒ´ (Antigen)
kn-keyword=�RŒ´ (Antigen)
en-keyword=‰^“®˜´�i (lncreased motility)
kn-keyword=‰^“®˜´�i (lncreased motility)
en-keyword=’Eè÷—± (Degranulation)
kn-keyword=’Eè÷—± (Degranulation)
en-keyword=ƒqƒXƒ^ƒ~ƒ“—V—£ (Histamine release)
kn-keyword=ƒqƒXƒ^ƒ~ƒ“—V—£ (Histamine release)
END

start-ver=1.4
cd-journal=joma
no-vol=103
cd-vols=
no-issue=1-2
article-no=
start-page=53
end-page=63
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1991
dt-pub=1991
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The role of endogenous thyrotropin releasing hormone (TRH) in maintenance of the blood pressure in awake and unrestrained rats with hemorrhagic hypotension
kn-title=–³–ƒ�Œ¥–³�S‘©‰ºƒ‰ƒbƒg‚Ì�oŒŒ�«’ጌˆ³ƒ‚ƒfƒ‹‚É‚¨‚¯‚é“àˆö�« Thyrotropin releasing hormone (TRH) ‚ÌŒŒˆ³ˆÛŽ��ì—p‚È‚ç‚Ñ‚É‚»‚Ì�ì—p•”ˆÊ‚ÉŠÖ‚·‚éŽÀŒ±“IŒ¤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A pressor effect of TRH in hemorrhagic hypotensive rats was studied. First, TRH (1mg/kg, 2mg/kg, 5mg/kg), its analogue MK771 (0.2mg/kg) and anti-TRH antibody were given intravenously. The change in the mean arterial blood pressure (MAP) was observed. After administration of TRH, MAP rose dose-dependently, and it also rose after administration of MK771. The anti-TRH antibody significantly suppressed the compensatory and reflective increase of MAP following the hemorrhage. This suggested that the endogenous TRH plays an important role in the maintenance of MAP in the hemorrhagic hypotensive state. Next, the same hypotention models were made using adreno-demedullated rats. TRH or anti-TRH antibody was given intravenously. TRH significantly increased MAP, while the anti-TRH antibody suppressed MAP. This indicates that the pressor effect of TRH is not mediated by the adrenal medulla. The endogenous TRH may play its maintenance role of blood pressure via medulla oblongata.
en-copyright=
kn-copyright=

en-aut-name=MiyazakiMineo
en-aut-sei=Miyazaki
en-aut-mei=Mineo
kn-aut-name=‹{�è•ô�¶
kn-aut-sei=‹{�è
kn-aut-mei=•ô�¶
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”–ƒ�Œ�E‘h�¶Šw‹³Žº
en-keyword=�oŒŒ�«’ጌˆ³
kn-keyword=�oŒŒ�«’ጌˆ³
en-keyword=TRH
kn-keyword=TRH
en-keyword=MK771
kn-keyword=MK771
en-keyword=�R TRH �R‘Ì
kn-keyword=�R TRH �R‘Ì
en-keyword=•›�t�‘Ž¿�œ‹Žƒ‰ƒbƒg
kn-keyword=•›�t�‘Ž¿�œ‹Žƒ‰ƒbƒg
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=5-6
article-no=
start-page=483
end-page=487
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=1992
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of fibromuscular dysplasia with large cerebral aneurysm at the bifurcation of the vertebral artery to cerebellar artery associated with renal hypertensin
kn-title=�t“®–¬�«�‚ŒŒˆ³‚É�„�œ“®–¬�\Œã‰º�¬”]“®–¬•ªŠò•”‹�‘å“®–¬áŽ‚ð�‡•¹‚µ‚½�üˆÛ‹Ø�«ˆÙŒ`�¬‚̈ê—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 27-year-old man was admitted with symptoms of hypertension and headache. His soft palate and uvula were deviated to the right. The left side of his tongue was atrophic with fasciculation. Plasma renin activity, plasma angiotensin-I and aldosteron levels were elevated. Renal arteriography revealed membranous-stenosis with poststenotic dilation at the mid and peripheral portion of the renal artery, which was consistent with the findings of fibromus-cular dysplasia (FMD). Large aneurysm at the bifucation of the vertebral artery to postero-inferior cerebellar artery was observed by cerebral arteriography. The patient was treated with medication for renal hypertension. Percutaneous embolization of the aneurysm was performed. In conclusion, the present case had a giant cerebral aneurysm, located at a rare portion and was diagnosed before its rupture. Examination of the cerebral artery was essential in renal FMD.
en-copyright=
kn-copyright=

en-aut-name=NakagawaHiroshi
en-aut-sei=Nakagawa
en-aut-mei=Hiroshi
kn-aut-name=’†�ì—T
kn-aut-sei=’†�ì
kn-aut-mei=—T
aut-affil-num=1
ORCID=

en-aut-name=KusachiShozo
en-aut-sei=Kusachi
en-aut-mei=Shozo
kn-aut-name=‘�’n�È‘ 
kn-aut-sei=‘�’n
kn-aut-mei=�È‘ 
aut-affil-num=2
ORCID=

en-aut-name=OkaTakefumi
en-aut-sei=Oka
en-aut-mei=Takefumi
kn-aut-name=‰ªŠx•¶
kn-aut-sei=‰ª
kn-aut-mei=Šx•¶
aut-affil-num=3
ORCID=

en-aut-name=UrabeNorio
en-aut-sei=Urabe
en-aut-mei=Norio
kn-aut-name=�è•”‘¥�¶
kn-aut-sei=�蕔
kn-aut-mei=‘¥�¶
aut-affil-num=4
ORCID=

en-aut-name=NogamiKunio
en-aut-sei=Nogami
en-aut-mei=Kunio
kn-aut-name=–ì�ã–M•v
kn-aut-sei=–ì�ã
kn-aut-mei=–M•v
aut-affil-num=5
ORCID=

en-aut-name=TakemotoMasao
en-aut-sei=Takemoto
en-aut-mei=Masao
kn-aut-name=’|–{‰ë—Y
kn-aut-sei=’|–{
kn-aut-mei=‰ë—Y
aut-affil-num=6
ORCID=

en-aut-name=MorishitaNaoya
en-aut-sei=Morishita
en-aut-mei=Naoya
kn-aut-name=�X‰º’¼–ç
kn-aut-sei=�X‰º
kn-aut-mei=’¼–ç
aut-affil-num=7
ORCID=

en-aut-name=InoueKimihito
en-aut-sei=Inoue
en-aut-mei=Kimihito
kn-aut-name=ˆä�ãŒö�m
kn-aut-sei=ˆä�ã
kn-aut-mei=Œö�m
aut-affil-num=8
ORCID=

en-aut-name=TsujiTakao
en-aut-sei=Tsuji
en-aut-mei=Takao
kn-aut-name=’Ò�F•v
kn-aut-sei=’Ò
kn-aut-mei=�F•v
aut-affil-num=9
ORCID=

en-aut-name=TomitaSusumu
en-aut-sei=Tomita
en-aut-mei=Susumu
kn-aut-name=•x“c‹œ
kn-aut-sei=•x“c
kn-aut-mei=‹œ
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰ÈŠw‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰ÈŠw‹³Žº

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰ÈŠw‹³Žº

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰ÈŠw‹³Žº

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰ÈŠw‹³Žº

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰ÈŠw‹³Žº

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰ÈŠw‹³Žº

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰ÈŠw‹³Žº

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê“à‰ÈŠw‹³Žº

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•””]�_ŒoŠO‰ÈŠw‹³Žº
en-keyword=�üˆÛ‹Ø�«ˆÙŒ`�¬
kn-keyword=�üˆÛ‹Ø�«ˆÙŒ`�¬
en-keyword=”]“®–¬áŽ
kn-keyword=”]“®–¬áŽ
en-keyword=�t“®–¬�«�‚ŒŒˆ³
kn-keyword=�t“®–¬�«�‚ŒŒˆ³
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=11-12
article-no=
start-page=1135
end-page=1144
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199212
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Examination of ANP secretion-atrial specific granules and hemodynamics
kn-title=ANP •ª”å�\ŒŒ�s“®‘Ô‚Æ“ÁŽêè÷—±‚ÉŠÖ‚·‚錟“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To clarify factors affecting atrial natriuretic peptide (ANP) secretion, the relationship between blood ANP level and intracardiac pressure, and that between the number of atrial specific granules (ASG) in the right atrial auricle and ANP level were investigated in 21 patients undergoing extracorporeal circulation. In the atrial loaded group, the Group TR (Tricuspid regurgitation) served as right atrial load and Group M (Mitral valve disease) as left atrial load, ANP and the number of ASG were compared with those in the control group. Accordingly, the effect of atrial load on ANP secretion and the number of ASG were investigated. Moreover, ANP and the number of ASG in the atrial myolysis group {Group A f(atrial fibrillation)} were compared with those of the sinus rhythm group to determine effect of atrio-myolysis. The ANP level showed a positive correlation with left atrial pressure (r=0.820 p<0.01) and with left ventricular end-diastolic pressure (r=0.726 p<0.01), but no correlation with right atrial pressure nor ventricular pressure. The ANP level in Group M was significantly higher than other groups, but there was no significant difference compared with Group TR. Consequently, the left atrium and rihgt atrium were considered to have different effects on ANP secretion.
en-copyright=
kn-copyright=

en-aut-name=AsanoHirotaka
en-aut-sei=Asano
en-aut-mei=Hirotaka
kn-aut-name=�ó–ì�O�F
kn-aut-sei=�ó–ì
kn-aut-mei=�O�F
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñŠO‰ÈŠw‹³Žº
en-keyword=“ÁŽêè÷—±
kn-keyword=“ÁŽêè÷—±
en-keyword=ANP
kn-keyword=ANP
en-keyword=•ª”å’²�ß
kn-keyword=•ª”å’²�ß
en-keyword=�¶�S–[
kn-keyword=�¶�S–[
en-keyword=‰E�S–[
kn-keyword=‰E�S–[
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=11-12
article-no=
start-page=1117
end-page=1125
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199212
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the role of interferon gamma (IFN-ƒÁ) in the pathogenesis of bronchial asthma : Evaluation of IFN-ƒÁ production induced by Candida or mite antigen in comparison with other factors of lymphocytic function
kn-title=‹CŠÇŽxšb‘§‚É‚¨‚¯‚é interferon-ƒÁ (IFN-ƒÁ) ŽY�¶”\‚ÉŠÖ‚·‚錤‹† ‘æ2•Ò ‹CŠÇŽxšb‘§‚É‚¨‚¯‚é IFN-ƒÁ ŽY�¶”\‚ÆŠeŽíƒŠƒ“ƒp‹…‹@”\‚Æ‚Ì”äŠrŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=It is known that IFN-ƒÁ, T-cell lymphokine, has potent effects on immunoglobulin synthesis, leukotrienes synthesis and delayed-type hypersensitivity. These factors are thought to be closely related to allergic reactions in bronchial asthma. Therefore, IFN-ƒÁ production from peripheral blood mononuclear cells induced by Candida or mite antigen was examined in asthmatics, and relations with other lymphocytic functions were studied to eluciate the role of IFN-ƒÁ. The results were as follows : (1) There was a significant correlation between IFN-ƒÁ production and Candida specific serum IgG1 antibody. (2) There was a significant correlation between IFN-ƒÁ production and lymphocyte blastgenesis induced by Candida antigen. (3) High levels of IFN-ƒÁ production were observed in asthmatics with positive late phase or delayed phase skin reaction to Candida antigen compared to asthmatics with negative late phase or delayed phase skin reaction. (4) Asthmatics with positive Candida or mite specific IgE radioallergosorbent test(RAST) showed a low level of IFN-ƒÁ production compared to asthmatics with negative IgE RAST. These results indicate that asthmatics with low IgE antibody and activated lymphocytes show high levels of IFN-ƒÁ production, and in these low IgE asthmatics, IFN-ƒÁ may play an important role in the allergic reactions of bronchial asthma.
en-copyright=
kn-copyright=

en-aut-name=KimuraGoro
en-aut-sei=Kimura
en-aut-mei=Goro
kn-aut-name=–Ø‘ºŒÜ˜Y
kn-aut-sei=ЯԼ
kn-aut-mei=ŒÜ˜Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰ÈŠw‹³Žº
en-keyword=bronchial asthma
kn-keyword=bronchial asthma
en-keyword=delayed-type hypersensitivity
kn-keyword=delayed-type hypersensitivity
en-keyword=IFN-ƒÁ
kn-keyword=IFN-ƒÁ
en-keyword=IgE antibody
kn-keyword=IgE antibody
en-keyword=IgG1 antibody
kn-keyword=IgG1 antibody
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=11-12
article-no=
start-page=1087
end-page=1091
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199212
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of gallbladder torsion diagnosed by abdominal CT prior to surgery
kn-title=• •” CT ŒŸ�¸‚ª�p‘O�f’f‚É—L—p‚Å‚ ‚Á‚½’_”X”P“]�Ç‚Ì1—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 77-year-old female with a chief complaint of epigastralgia was diagnosed with torsion of the gallbladder by abdominal CT prior to surgery and successfully treated by an emergency operation. Only 16 cases of gallbladder torsion including the present case have been diagnosed prior to surgery in Japan. Almost all of them were diagnosed with abdominal ultrasonography. With the growing use of CT in the evaluation of abdominal pain, preoperative diagnosis of the condition may be expedited. CT shows characteristic findings of torsion of the gallbladder such as 1) pronounded swelling of the gallbladder and circumscribed thickening of the gallbladder wall, 2) displacement of the gallbladder, and 3) volvulated gallbladder neck. We found CT to be useful for preoperative diagnosis of patients with abdominal pain.
en-copyright=
kn-copyright=

en-aut-name=YunokiYasuhiro
en-aut-sei=Yunoki
en-aut-mei=Yasuhiro
kn-aut-name=—M–Ø–õ�O
kn-aut-sei=—M–Ø
kn-aut-mei=–õ�O
aut-affil-num=1
ORCID=

en-aut-name=MiyakeMikio
en-aut-sei=Miyake
en-aut-mei=Mikio
kn-aut-name=ŽO‘îŽOŠì’j
kn-aut-sei=ŽO‘î
kn-aut-mei=ŽOŠì’j
aut-affil-num=2
ORCID=

en-aut-name=MiyagiKouji
en-aut-sei=Miyagi
en-aut-mei=Kouji
kn-aut-name=‹{–ØŒ÷ŽŸ
kn-aut-sei=‹{–Ø
kn-aut-mei=Œ÷ŽŸ
aut-affil-num=3
ORCID=

en-aut-name=NakagawaHidekazu
en-aut-sei=Nakagawa
en-aut-mei=Hidekazu
kn-aut-name=’†�ì�G˜a
kn-aut-sei=’†�ì
kn-aut-mei=�G˜a
aut-affil-num=4
ORCID=

en-aut-name=MatsuoYouji
en-aut-sei=Matsuo
en-aut-mei=Youji
kn-aut-name=�¼”ö—m“ñ
kn-aut-sei=�¼”ö
kn-aut-mei=—m“ñ
aut-affil-num=5
ORCID=

en-aut-name=NakagouJitsuo
en-aut-sei=Nakagou
en-aut-mei=Jitsuo
kn-aut-name=’†‹½ŽÀ—Y
kn-aut-sei=’†‹½
kn-aut-mei=ŽÀ—Y
aut-affil-num=6
ORCID=

en-aut-name=LiuMiao
en-aut-sei=Liu
en-aut-mei=Miao
kn-aut-name=—«ûE
kn-aut-sei=—«
kn-aut-mei=ûE
aut-affil-num=7
ORCID=

en-aut-name=FuchimotoSadanori
en-aut-sei=Fuchimoto
en-aut-mei=Sadanori
kn-aut-name=•£–{’è‹V
kn-aut-sei=•£–{
kn-aut-mei=’è‹V
aut-affil-num=8
ORCID=

en-aut-name=OritaKunzo
en-aut-sei=Orita
en-aut-mei=Kunzo
kn-aut-name=�Ü“cŒOŽO
kn-aut-sei=�ܓc
kn-aut-mei=ŒOŽO
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=‹Ê–ìŽOˆä•a‰@ŠO‰È

affil-num=2
en-affil=
kn-affil=‹Ê–ìŽOˆä•a‰@ŠO‰È

affil-num=3
en-affil=
kn-affil=‹Ê–ìŽOˆä•a‰@ŠO‰È

affil-num=4
en-affil=
kn-affil=‹Ê–ìŽOˆä•a‰@ŠO‰È

affil-num=5
en-affil=
kn-affil=‹Ê–ìŽOˆä•a‰@ŠO‰È

affil-num=6
en-affil=
kn-affil=‹Ê–ìŽOˆä•a‰@“à‰È

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆê•a—�Šw‹³Žº

affil-num=8
en-affil=
kn-affil=’†�‘“d—ÍŠ”Ž®‰ïŽÐ’†“d•a‰@ŠO‰È

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº
en-keyword=’_”X”P“]�Ç
kn-keyword=’_”X”P“]�Ç
en-keyword=�p‘O�f’f
kn-keyword=�p‘O�f’f
en-keyword=• •” CT ŒŸ�¸
kn-keyword=• •” CT ŒŸ�¸
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=1-2
article-no=
start-page=187
end-page=194
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=1992
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An expert system for valvular heart disease using MRI and its clinical applications
kn-title=�S‘Ÿ•Ù–Œ�Ç‚ÌMR‰æ‘œ�f’fŽx‰‡ƒVƒXƒeƒ€‚ÌŠJ”­‚Æ‚»‚Ì—Õ�°‰ž—p‚ÉŠÖ‚·‚錤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=MRI is a valuable tool for diagnosing heart disease today. The cardiac blood flow is determined by an MRI image analysis and expert system. Image data are taken by a TV camera and digitalized. After gray level thresholding and region segmentation, the boundary of the regurgitant flow region is precisely extracted. Using this expert system, a doctor can easily make an accurate diagnosis of the valvular heart disease. This method should prove useful for the diagnosis of various heart diseases.
en-copyright=
kn-copyright=

en-aut-name=NakagawaTomio
en-aut-sei=Nakagawa
en-aut-mei=Tomio
kn-aut-name=’†�ì•x•v
kn-aut-sei=’†�ì
kn-aut-mei=•x•v
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº
en-keyword=expert system
kn-keyword=expert system
en-keyword=MRI
kn-keyword=MRI
en-keyword=valvular heart disease
kn-keyword=valvular heart disease
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=11-12
article-no=
start-page=1059
end-page=1068
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199212
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Evaluation of myocardial damage and cardiac residual capacity by Tl-201 myocardial scintigraphy in valvular heart diseases
kn-title=Tl-201�S‹ØƒVƒ“ƒ`ƒOƒ‰ƒtƒB�[‚ð—p‚¢‚½�S‘Ÿ•Ù–Œ�Ç‚É‚¨‚¯‚é�S‹Ø�«�ó‹y‚Ñ�S—\”õ”\‚Ì•]‰¿
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=This study was performed to clarify whether the extent-score (Ex-Score) calculated by Tl-201 myocardial scintigraphy is a reliable indicator of the severity of myocardial damage and cardiac residual capacity in valvular heart diseases. The subjects consisted of 38 patients (10 with aortic regurgitation (AR), 4 with aortic stenosis (AS), 13 with mitral regurgitation (MR) and 11 with mitral stenosis (MS)). Ex-Score were significantly correlated with the severity of myocardial damage found in biopsied specimens obtained intraoperatively (correlation efficiency to Ex-Score with cell diameter in AR, % fibrosis in AR, cell diameter in AS, electron microscopic score in MR and % fibrosis in MS was 0.873, 0.734, 0.970, 0.913 and 0.659, respectively). Ex-Score were also correlated with cardiac residual capacity determined by radioisotope angiography (correlation efficiency to Ex-Score with % ઠejection fraction in AR,  % ઠend-systolic volume in MR,  % ઠend-diastolic volume in MS was -0.764, 0.790 and -0.763, respectively). These results suggest that the severity of myocardial damage and cardiac residual capacity can be estimated by Tl-201 myocardial scintigraphy (Ex-Score) in valvular heart diseases.
en-copyright=
kn-copyright=

en-aut-name=IndoShunju
en-aut-sei=Indo
en-aut-mei=Shunju
kn-aut-name=ˆö“¡�t�H
kn-aut-sei=ˆö“¡
kn-aut-mei=�t�H
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñŠO‰ÈŠw‹³Žº
en-keyword=Tl-201�S‹ØƒVƒ“ƒ`ƒOƒ‰ƒtƒB�[
kn-keyword=Tl-201�S‹ØƒVƒ“ƒ`ƒOƒ‰ƒtƒB�[
en-keyword=Extent Score
kn-keyword=Extent Score
en-keyword=�S‹ØŠÔ�üˆÛ—Ê
kn-keyword=�S‹ØŠÔ�üˆÛ—Ê
en-keyword=�S‹Ø�×–E‰¡Œa
kn-keyword=�S‹Ø�×–E‰¡Œa
en-keyword=“dŒ°ƒXƒRƒA
kn-keyword=“dŒ°ƒXƒRƒA
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=9-10
article-no=
start-page=923
end-page=929
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199210
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Combined resection of lung cancer and invaded aorta with the use of simple temporary bypass : A case reort
kn-title=”xŠà‚É‚¨‚¯‚éŠÈˆÕŽ®ˆêŽžƒoƒCƒpƒX–@‚ð—p‚¢‚½‘å“®–¬�‡•¹�Ø�œ‚̈ê—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Left pneumonectomy and concomitant resection of the invaded aorta were performed by the simple temporary bypass method. The patient was a 59-year-old male with the chief complaint of left thoracic pain. The 57�~43�~35 mm tumor was in a region centering on segment 6 of the left lung and had infiltrated the descending aorta. It was diagnosed as T4NOMO, Stage IIIb. A bypass for blood flow was established between the aortic arch avobe the invasion and the left femoral artery, after ligation of the pulmonary artery and vein and closure of the left bronchial stump. Vascular blocking forceps were applied to the descending aorta above and below the tumor infiltration, and two thirds of the circumference of the invaded aortic wall, 4.0�~3.0 cm, along with the tumor, was resected. Reconstruction was performed with an 18mm Cooly double velour graft. Blood pressure was monitored with a pressure probe inserted into the right femoral artery. It did not fall below 60 mmHg during the operation. Local recurrence was observed 10 montns post-operatively, and the patient is now receiving radiation therapy.
en-copyright=
kn-copyright=

en-aut-name=InoueFumiyuki
en-aut-sei=Inoue
en-aut-mei=Fumiyuki
kn-aut-name=ˆä�㕶”V
kn-aut-sei=ˆä�ã
kn-aut-mei=•¶”V
aut-affil-num=1
ORCID=

en-aut-name=KamikawaYasuaki
en-aut-sei=Kamikawa
en-aut-mei=Yasuaki
kn-aut-name=�ã�ì�N–¾
kn-aut-sei=�ã�ì
kn-aut-mei=�N–¾
aut-affil-num=2
ORCID=

en-aut-name=NaomotoYoshio
en-aut-sei=Naomoto
en-aut-mei=Yoshio
kn-aut-name=—P–{—Ç•v
kn-aut-sei=—P–{
kn-aut-mei=—Ç•v
aut-affil-num=3
ORCID=

en-aut-name=GouchiAkira
en-aut-sei=Gouchi
en-aut-mei=Akira
kn-aut-name=�‡’n–¾
kn-aut-sei=�‡’n
kn-aut-mei=–¾
aut-affil-num=4
ORCID=

en-aut-name=OritaKunzo
en-aut-sei=Orita
en-aut-mei=Kunzo
kn-aut-name=�Ü“cŒOŽO
kn-aut-sei=�ܓc
kn-aut-mei=ŒOŽO
aut-affil-num=5
ORCID=

en-aut-name=HataTakato
en-aut-sei=Hata
en-aut-mei=Takato
kn-aut-name=”¨—²“o
kn-aut-sei=Ӭ
kn-aut-mei=—²“o
aut-affil-num=6
ORCID=

en-aut-name=KuinoseMasahiko
en-aut-sei=Kuinose
en-aut-mei=Masahiko
kn-aut-name=�Yƒm�£�¹•F
kn-aut-sei=�Yƒm�£
kn-aut-mei=�¹•F
aut-affil-num=7
ORCID=

en-aut-name=NanbaHirofumi
en-aut-sei=Nanba
en-aut-mei=Hirofumi
kn-aut-name=“ï”g�G•¶
kn-aut-sei=“ï”g
kn-aut-mei=�G•¶
aut-affil-num=8
ORCID=

en-aut-name=TaniguchiGyou
en-aut-sei=Taniguchi
en-aut-mei=Gyou
kn-aut-name=’JŒûêŸ
kn-aut-sei=’JŒû
kn-aut-mei=êŸ
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº

affil-num=6
en-affil=
kn-affil=�S‘Ÿ•aƒZƒ“ƒ^�[�匴•a‰@ŠO‰È

affil-num=7
en-affil=
kn-affil=�S‘Ÿ•aƒZƒ“ƒ^�[�匴•a‰@ŠO‰È

affil-num=8
en-affil=
kn-affil=�S‘Ÿ•aƒZƒ“ƒ^�[�匴•a‰@ŠO‰È

affil-num=9
en-affil=
kn-affil=�S‘Ÿ•aƒZƒ“ƒ^�[�匴•a‰@ŠO‰È
en-keyword=ŠÈˆÕŽ®ˆêŽžƒoƒCƒpƒX
kn-keyword=ŠÈˆÕŽ®ˆêŽžƒoƒCƒpƒX
en-keyword=‘å“®–¬�‡•¹�Ø�œ
kn-keyword=‘å“®–¬�‡•¹�Ø�œ
en-keyword=�i�s�«”xŠà
kn-keyword=�i�s�«”xŠà
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=1-2
article-no=
start-page=97
end-page=106
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=1992
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Attitude toward mental disorders : A comparative study of a attitude of nurses and attendants between Japan and Brazil
kn-title=�¸�_�áŠQ‚̑΂·‚é‘Ô“x�\“ú–{, ƒuƒ‰ƒWƒ‹‚ÌŠÅŒì•w, ŠÅŒìŽm‚Ì‘Ô“x‚Ì”äŠrŒ¤‹†�\
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Attitude of nureses and attendants toward mental disorders was studied by using question-naire in Japan and Brazil. By factor analysis, three factors, negative attitude toward mental disorders and misunder-standing, positive attitude toward mental disorders and mental health ideology were extracted. The score of negative attitude toward mental disorders and misunderstanding was high in Brazil. This was suspected to be caused by poor knowledge about mental disorders. The score of positive attitude toward mental disorders was similar in Japan and Brazil. The score of mental health ideology was high in Japan. Mental health ideology is important to improve the attitude toward mental disorders both Japan and Brazil. It is important to spread knowledge about mental disorders in Brazil. In Japan, it is important to increase the interest in mental disorders.
en-copyright=
kn-copyright=

en-aut-name=TakenamiKatsuko
en-aut-sei=Takenami
en-aut-mei=Katsuko
kn-aut-name=•�“ì�ŽŽq
kn-aut-sei=•�“ì
kn-aut-mei=�ŽŽq
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”�_Œo�¸�_ˆãŠw‹³Žº
en-keyword=�¸�_�áŠQ‚ɑ΂·‚é‘Ô“x
kn-keyword=�¸�_�áŠQ‚ɑ΂·‚é‘Ô“x
en-keyword=ˆöŽq•ª�Í
kn-keyword=ˆöŽq•ª�Í
en-keyword=�¸�_•ÛŒ’“IŠÏ”O
kn-keyword=�¸�_•ÛŒ’“IŠÏ”O
en-keyword=ŠÖ�S“x
kn-keyword=ŠÖ�S“x
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=9-10
article-no=
start-page=885
end-page=895
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199210
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The effect of nutritional intake on energy metabolism in postoperative patients after gastrointestinal surgery
kn-title=ŠÔ�Ú”M—Ê‘ª’è‚É‚æ‚é�Á‰»ŠíŽè�pŒã‚̃Gƒlƒ‹ƒM�[‘ãŽÓ‚ÌŒŸ“¢�\“Š—^—Ê¥“Š—^Œo˜H‚Ì”äŠr�\
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Many studies have shown that enteral nutrition (EN) has nutritional effects comparable to total parenteral nutrition (TPN). However, the energy metabolism of the two different nutritioanl methods remains undefined. The two nutritional methods were compared by measuring the resting energy expenditure (REE) and nutritional assessment in postoperative patients after gastrointestinal surgery. The effects of different amounts of EN were also evaluated. Patients were diveded into three groups : Patients who were fed by EN of 30 Cal/kg/day (Group I, EN 30 : n=8), patients who were fed by EN of 40 Cal/kg/day (Group II, EN 40 : n=8), and patients who were fed by TPN of 30 Cal/kg/day (Group III, TPN : n=8). REE was measured by the Datex indirect calorimetry and nutritional assessment included the measurements of triceps skinfold thickness (TSF), arm muscle circumference (AMC), albumin and rapid turnover proteins. �“REE/BEE of EN30, EN40 and TPN was 122.5�}14.3%, 138.2�}16.8% and 107.6�}10.5% respectively. The RQ for the three groups was about 1.0, which means the energy source of all regimens is carbohydrate. The TPN group showed a significantly higher RQ than the EN groups, but there was no difference in albumin or transferrin. There was no difference in nutritional effect between EN 30 and EN 40. No difference was found in anthropometric effects among the three groups. These findings suggest that 30 Cal/kg/day would be preferable to 40 Cal/kg/day in energy supply of enteral nutrition and that the energy expenditure of EN is higher than that of TPN under 30 Cal/kg/day nutrition. There is no difference among the three mehtods in terms of nutritional effects.
en-copyright=
kn-copyright=

en-aut-name=YoshizaneKen
en-aut-sei=Yoshizane
en-aut-mei=Ken
kn-aut-name=‹g›‰Œ›
kn-aut-sei=‹g›‰
kn-aut-mei=Œ›
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñŠO‰ÈŠw‹³Žº
en-keyword=ŠÔ�Ú”M—ÊŒv
kn-keyword=ŠÔ�Ú”M—ÊŒv
en-keyword=Œo’°‰h—{
kn-keyword=Œo’°‰h—{
en-keyword=Œo�Ö¬‰h—{
kn-keyword=Œo�Ö¬‰h—{
en-keyword=‘ãŽÓ”M—Ê
kn-keyword=‘ãŽÓ”M—Ê
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=9-10
article-no=
start-page=871
end-page=884
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199210
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Experimental study on cerebral venous circulatory disturbance
kn-title=”]�Ö¬ŠÂ—¬�áŠQ‚ÉŠÖ‚·‚éŽÀŒ±“IŒ¤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A new experimental model of cerebral venous occlusion was developed and the cerebral hemodynamics and water content using this model were studied. An anatomical study of the cerebral venous system using methacyrl resin showed that the venous system was composed of superficial and deep veins. The superficial veins drained into the superior sagittal sinus (SSS). The SSS was connected to internal and external jugular veins via the transverse sinuses and diploic veins (DV), respectively. The cats were divided into three groups on the basis of the occlusion sites as follows ; Group I : SSS occlusion, Group II : DV occlusion, Group III : occlusion of both the SSS and DV. Intracranial pressure (ICP) and cerebral blood volume (CBV, photoelectric method) were monitored continuously. Local cerebral blood flow (1-CBF) and water content were measured by hydrogen clearance and gravimetric methods, respectively. Somatosensory evoked potential (SEP) was also recorded. Evans blue was injected intravenously to evaluate blood brain barrier permeability. There were no siginificant changes in ICP, 1-CBF or N1 latency of SEP after the occlusioon in Group I or II. However, in Group III, 1-CBF decreased significantly 2 hours after the occlusion as ICP increased gradually. N1 latency of SEP was prolonged and water content increased significantly. CBV increased immediately after the occlusion. There was no extravasated Evans blue. The increase in CBV and water content during sinus occlusion appeared to have led to intracranial hypertension and decrease of 1-CBF, which resulted in neural dysfunction. The brain edema in this model seemed to be hydrostatic edema or cytotoxic edema.
en-copyright=
kn-copyright=

en-aut-name=SaijoToshikazu
en-aut-sei=Saijo
en-aut-mei=Toshikazu
kn-aut-name=�¼�ðŽõˆê
kn-aut-sei=�¼�ð
kn-aut-mei=Žõˆê
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•””]�_ŒoŠO‰ÈŠw‹³Žº
en-keyword=cerebral venous circulatory disturbance
kn-keyword=cerebral venous circulatory disturbance
en-keyword=dural sinus occlusion
kn-keyword=dural sinus occlusion
en-keyword=brain edema
kn-keyword=brain edema
en-keyword=cerebral blood flow
kn-keyword=cerebral blood flow
en-keyword=cerebral blood volume
kn-keyword=cerebral blood volume
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=7-8
article-no=
start-page=809
end-page=820
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199208
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on IgG subclass antibodies in asthmatics with late asthmatic responses Part 2. Antigen-specific IgG subclass antibodies in the BALF of asthmatics with late asthmatic responses
kn-title=’x”­Œ^‹C“¹”½‰ž‚É‚¨‚¯‚éIgG ƒTƒuƒNƒ‰ƒX�R‘Ì‚ÉŠÖ‚·‚錤‹†�@‘æ2•Ò�@‹CŠÇŽx”x–E�ô�ò‰t’†�RŒ´“ÁˆÙ“I IgG ƒTƒuƒNƒ‰ƒX�R‘Ì‚Æ’x”­Œ^‹C“¹”½‰ž‚ÌŠÖ˜A‚ɂ‚¢‚Ä
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Immunoglobulin classes which induce a non-immediate asthmatic response (non-IAR) in the case of low level of IgE antibody are still unknown, although IAR is mediated by IgE. To elucidate the relationship between antibodies and late asthmatic responses (LAR), antigen-specific IgG subclass antibodies in the serum and bronchoalveolar lavage fluid (BALF) of asthmatics were measured by avidin-biotin ELISA before provocation by antigen. The BALF levels of IgG and IgG1 antibodies to mite and Candida antigen in bronchial asthmatics were higher than those in healthy subjects (p<0.05). Followed by inhalation of house dust or Candida antigen, bronchial asthmatics were divided into group A (higher levels of BALF IgG1 antibody) and gourp B (lower levels of BALF IgG1 antibody). The percentages of LAR including DAR after inhalation of house dust antigen in group A were significantly higher than those in group B (p<0.05). The percentages of LAR including DAR after inhalation of Candida antigen in group A were significantly higher than those in group B (p<0.01). In asthmatics with LAR after inhalation of house dust antigen or Candida antigen, the BALF levels of antigen-specific IgG and IgG1 antibodies were significantly higher than those in asthmatics without LAR of healthy subjects (p<0.01). In asthmatics with LAR after inhalation of house dust antigen or Candida antigen, the BALF levels of antigen-specific IgG and IgG1 antibodies were significantly higher than those in asthmatics without LAR of healthy subjects (p<0.01). In asthmatics with LAR, the relative (to albumin) of coefficients of excretion (RCE) in the BALF of antigen-specific IgG and IgG1 antibodies were higher than those in asthmatics without LAR of healthy subjects. These findings suggest that local production of antigen-specific IgG and IgG1 antibodies incerases in asthmatics with LAR, and that these antibodies may induce LAR.
en-copyright=
kn-copyright=

en-aut-name=OgurusuKazuro
en-aut-sei=Ogurusu
en-aut-mei=Kazuro
kn-aut-name=�¬ŒI�²˜a˜Y
kn-aut-sei=�¬ŒI�²
kn-aut-mei=˜a˜Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰ÈŠw‹³Žº
en-keyword=’x”­Œ^‹C“¹”½‰ž
kn-keyword=’x”­Œ^‹C“¹”½‰ž
en-keyword=IgG ƒTƒuƒNƒ‰ƒX�R‘Ì
kn-keyword=IgG ƒTƒuƒNƒ‰ƒX�R‘Ì
en-keyword=‹CŠÇŽx”x–E�ô�ò
kn-keyword=‹CŠÇŽx”x–E�ô�ò
en-keyword=“�«šb‘§
kn-keyword=“�«šb‘§
en-keyword=�RŒ´‹z“ü—U”­ŽŽŒ±
kn-keyword=�RŒ´‹z“ü—U”­ŽŽŒ±
END

start-ver=1.4
cd-journal=joma
no-vol=104
cd-vols=
no-issue=7-8
article-no=
start-page=797
end-page=807
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199208
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on IgG subclass antibodies in asthmatics with late asthmatic responses Part 1. Serum antigen-specific IgG subclass antibodies in asthmatics with late asthmatic response
kn-title=’x”­Œ^‹C“¹”½‰ž‚É‚¨‚¯‚éIgG ƒTƒuƒNƒ‰ƒX�R‘Ì‚ÉŠÖ‚·‚錤‹†�@‘æ1•Ò�@ŒŒ�´’†�RŒ´“ÁˆÙ“I IgG ƒTƒuƒNƒ‰ƒX�R‘Ì‚Æ’x”­Œ^‹C“¹”½‰ž‚ÌŠÖ˜A‚ɂ‚¢‚Ä
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The immediate asthmatic response is mainly induced by IgE-dependent mechanisms. However, the late asthmatic response (LAR) is induced by inhalation of antigens without the participation of antigen-specific IgE antibodies in some asthmatics, especially in intractable asthma induced by Candida antigen. To elucidate the relationship between antibodies and those bronchial responses, the antigen-specific IgG subclass antibodies in sera from asthmatics were measureed and compared with IgE antibody. The avidin-biotin ELISA (enzyme-linked immunosorbent assay) method was established for the measurement of specific IgG and IgG subclass antibodies to mite or Candida antigen. Serum levels of IgG and IgG1 antibodies to mite and Candida antigen in bronchial asthmatics were significantly higher than those in healthy subjects (p<0.01). Bronchial asthmatics who were tested with inhalation of house dust or Candida antigen were divided into group A (higher levels of serum IgG1 antibody) and group B (lower levels of serum IgG1 antibody). The percentage of LAR including DAR after inhalation of house dust antigen in group A were significantly higher than those in group B (p<0.01). The percentages of LAR and LAR including DAR after inhalation of Candida antigen in group A were significantly higherSerum levels of house du than those in group B(p<0.01). Serum levels of antigen-specific IgG and IgG1 antibodies in asthmatics with LAR after inhalation of house dust or Candida antigen were significantly higher than those in asthmatics with IAR or non-responders (p<0.01). The serum level of specific IgE antibody to these antigens in asthmatics with LAR after inhalation of house dust or Candida antigen was slightly lower than that in the asthmatics without LAR, though the difference was not significant. These findings suggest that high serum levels of specific IgG and IgG1 antibodies to adequate antigens play a role in inducing an attack in asthmatics with LAR.
en-copyright=
kn-copyright=

en-aut-name=OgurusuKazuro
en-aut-sei=Ogurusu
en-aut-mei=Kazuro
kn-aut-name=�¬ŒI�²˜a˜Y
kn-aut-sei=�¬ŒI�²
kn-aut-mei=˜a˜Y
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰ÈŠw‹³Žº
en-keyword=’x”­Œ^‹C“¹”½‰ž
kn-keyword=’x”­Œ^‹C“¹”½‰ž
en-keyword=I‚‡G ƒTƒuƒNƒ‰ƒX�R‘Ì
kn-keyword=I‚‡G ƒTƒuƒNƒ‰ƒX�R‘Ì
en-keyword=IgE �R‘Ì
kn-keyword=IgE �R‘Ì
en-keyword=�RŒ´‹z“ü—U”­ŽŽŒ±
kn-keyword=�RŒ´‹z“ü—U”­ŽŽŒ±
en-keyword=“�«šb‘§
kn-keyword=“�«šb‘§
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=5-6
article-no=
start-page=539
end-page=547
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Mechanism of immunotherapy related to the production of antigen specific IgG subclass antibodies and leukotrienes in bronchial asthmatics
kn-title=‹CŠÇŽxšb‘§Š³ŽÒ‚É‚¨‚¯‚錸Š´�ì—Ö@‚É�ì—p‹@�˜‚ÉŠÖ‚·‚錤‹†�\�RŒ´“ÁˆÙ“IIgGƒTƒuƒNƒ‰ƒX�R‘̂ƃ�ƒCƒRƒgƒŠƒGƒ“ŽY�¶”\‚É‹y‚Ú‚·‰e‹¿‚ɂ‚¢‚Ä�\
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To clarify the mechanism of immunotherapy in bronchial asthma, the level of mite specific IgG subclass asntibodies (total IgG, IgG(1), IgG(4)) and the production of leukotrienes (LTB(4), LTC(4)) released from leukocytes were examined. Eighteen mite-sensitive asthmatic patiens who received immunotherapy with house dust extract for 1 year were dividel into two groups, the responsive patients and non-responsive patients. Before treatment and 1 year after treatment, the levels of mite specific serum IgG subclass antibodies were measured by enzyme-linked immunosorbent assay (ELISA) and the levels of LTs were measured by high performance liquid chromatography (HPLC). In the responsive group, the level of mite specific serum IgG(4) antibody was significantly increased (p<0.05), and the level of mite specific serum total IgG and IgG(1) antibody was decreased. The release of LTB(4) and LTC(4) from leukocytes stimulated by mite antigen was significantly decreased (p<0.05,p<0.05).
 These results indicate that increases in the antigen specific IgG(4) and the inhibiton of chemical madiators play important roles in the mechanism of immunotherapy.
en-copyright=
kn-copyright=

en-aut-name=KatagiSachie
en-aut-sei=Katagi
en-aut-mei=Sachie
kn-aut-name=•Ð–Ø�KŒb
kn-aut-sei=•Ð–Ø
kn-aut-mei=�KŒb
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰ÈŠw‹³Žº
en-keyword=bronchial asthma
kn-keyword=bronchial asthma
en-keyword=immunotherapy
kn-keyword=immunotherapy
en-keyword=IgG subclass antibodies
kn-keyword=IgG subclass antibodies
en-keyword=leukotrienes
kn-keyword=leukotrienes
END

start-ver=1.4
cd-journal=joma
no-vol=105
cd-vols=
no-issue=5-6
article-no=
start-page=489
end-page=498
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1993
dt-pub=1993
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical trial of enhancement method fro ultrasonographic diagnosis of thyroid nodules
kn-title=Œ‹�ß�«�b�ó‘BŽî‚Ì’´‰¹”g�f’f‚É‚¨‚¯‚é Enhancement –@‚ÌŽŽ‚Ý
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Enhancement in thyroid ultrasonography was investigated with thyroid lymphography by injection of Lipiodol into thyroid nodules in 50 patients. On plain thyroid ultrasonography (PU), the echo levels of normal and tumorous portions of the thyroid glands were evaluated. Then, the echo level ratios (P-N/T) were calculated. Moreover, by the same method, the echo level ratios between normal and tumorous portions of the thyroid glands were culculated 6 hours after Lipiodol injection (E-N/T), when the greatest enhancement was anticipated. The mean value of P-N/T was 1.305, and that of E-N/T was 1.474. The echo level ratio was significantly elevated in the enhancement method (p<0.0014). We concluded that the enhancement is obtained with Lipiodol injection into the normal portion of the thyroid glands, regardless of whether the tumor is benign or malignant and with or without cystic degeneration. This method is useful in promoting quality and location diagnosis of thyroid nodules. N : echo level value in the normal portion of thyroid gland T : echo level value in the tumorous portion of thyroid gland N/T : echo level raito
en-copyright=
kn-copyright=

en-aut-name=TakeuchiRyuzo
en-aut-sei=Takeuchi
en-aut-mei=Ryuzo
kn-aut-name=’|“à—´ŽO
kn-aut-sei=’|“à
kn-aut-mei=—´ŽO
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñŠO‰ÈŠw‹³Žº
en-keyword=’´‰¹”g�f’f
kn-keyword=’´‰¹”g�f’f
en-keyword=Œ‹�ß�«�b�ó‘BŽî
kn-keyword=Œ‹�ß�«�b�ó‘BŽî
en-keyword=Enhancement
kn-keyword=Enhancement
en-keyword=�b�ó‘BƒŠƒ“ƒp‘¢‰e
kn-keyword=�b�ó‘BƒŠƒ“ƒp‘¢‰e
en-keyword=ƒGƒR�[ƒŒƒxƒ‹
kn-keyword=ƒGƒR�[ƒŒƒxƒ‹
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=3-4
article-no=
start-page=415
end-page=428
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=1994
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Analysis of the dynamic states of pulmonary ventilation and perfusion in bronchial asthmatics using (133)Xe gas ventilation scintigraphy and (99m)Tc-MAA lung perfusion scintigraphy
kn-title=‹CŠÇŽxšb‘§‚É‚¨‚¯‚銷‹CŒŒ—¬“®‘Ô‚ÌŒ¤‹†�\(133)XeŠ·‹CƒVƒ“ƒ`‹y‚Ñ(99m)Tc-MAAŒŒ—¬ƒVƒ“ƒ`‚É‚æ‚錟“¢�\
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To clarify the organic changes and pathophysiology of the lungs in intractable asthmatics, the dynamic states of pulmonary ventilation and perfusion were analyzed in 15 bronchial asthmatic in the stable state using (133)Xe gas ventilation scintigraphy and (99m)Tc-MAA lung perfusion scintigraphy, respectively. Dysfunction of pulmonary ventilation and impairment of pulmonary perfusin were significantly severer in intractable asthmatics than in non-intractable asthmatics (p<0.01, P<0.05, respectively) and those of asthma caused by aging. Late onset asthmatics with a long duration of disease tended to show severe impairment of pulmonary perfusion. Above all the longer the duration of the disease the severer became the impairment of pulmonary perfusion in late onset intractable asthmatics (LOIA). These findings suggest that the progression of irreversible organic changes of lungs in LOIA is involved in the severity of brochial asthma.
en-copyright=
kn-copyright=

en-aut-name=IshihamaHidenobu
en-aut-sei=Ishihama
en-aut-mei=Hidenobu
kn-aut-name=�Îà_‰p’¨
kn-aut-sei=�Îà_
kn-aut-mei=‰p’¨
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰ÈŠw‹³Žº
en-keyword=‹CŠÇŽxšb‘§
kn-keyword=‹CŠÇŽxšb‘§
en-keyword=’†�‚”N”­�ÇŒ^“�«šb‘§ (LOIA)
kn-keyword=’†�‚”N”­�ÇŒ^“�«šb‘§ (LOIA)
en-keyword=Š·‹CƒVƒ“ƒ`
kn-keyword=Š·‹CƒVƒ“ƒ`
en-keyword=ŒŒ—¬ƒVƒ“ƒ`
kn-keyword=ŒŒ—¬ƒVƒ“ƒ`
END

start-ver=1.4
cd-journal=joma
no-vol=105
cd-vols=
no-issue=1-2
article-no=
start-page=97
end-page=106
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1993
dt-pub=19930227
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on the pathogenesis of allergic gastroenteropathy Part 2. Existence of allergic gastroenteropathy caused by house dust
kn-title=ƒAƒŒƒ‹ƒM�[�«ˆÝ’°�Ç‚Ì•a‘Ô‚ÉŠÖ‚·‚錤‹† ‘æ2•Ò ƒnƒEƒXƒ_ƒXƒg‚É‹Nˆö‚·‚éƒAƒŒƒ‹ƒM�[�«ˆÝ’°�Ç‚Ì‘¶�Ý‚ÉŠÖ‚·‚錟“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Not only many food substances but also other substances such as house dust(HD) may serve as causative allergens of allergic gastroenteropathy. To clarify the causative allergens and the pathogenesis of allergic gastroenteropathy, an oral loading test using HD, was applied to two patients with allergic gastroenteropathy caused by an unknown antigen, and with HD-sensitivity, and 24 bronchial asthmatics with or without HD-sensitivity, ther were examined using the ultrasonography of stomach reported previously. Two patients with gastroenteropathy showed a positive skin test and IgE RAST to HD, although they had bronchial asthma in the past history. Peripheral blood eosinophils in the 1st and 2nd patients showed a high (max 78%) and slightly increased (9%) value. The precipitating antibody in the two cases was negative, but lymphocyte blastogenesis to HD was enhanced in one case. During the oral loading test using HD, both patients had abdominal pain at immediate and late phase and acceleration of gastric peristalic movements was confirmed by ultrasonography. One of the 2 patients showed a strong gastrointestinal reaction during the delayed phase. LTC4 and histamine were considered to be involved in the abdominal pain of these cases. One of the 12 patients with bronchial asthma and HD-sensitivity showed an immediate reaction in oral loading test without abdominal pain, suggensting a correlation of the hypersensitivity between the bronchi and the digestive tract, including 2 former cases.
en-copyright=
kn-copyright=

en-aut-name=ToyotaYuji
en-aut-sei=Toyota
en-aut-mei=Yuji
kn-aut-name=–L“c—TŽ¡
kn-aut-sei=–L“c
kn-aut-mei=—TŽ¡
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰ÈŠw‹³Žº
en-keyword=ƒAƒŒƒ‹ƒM�[�«ˆÝ’°�Ç
kn-keyword=ƒAƒŒƒ‹ƒM�[�«ˆÝ’°�Ç
en-keyword=ŒoŒû•‰‰×ŽŽŒ±
kn-keyword=ŒoŒû•‰‰×ŽŽŒ±
en-keyword=’´‰¹”g‘–�¸–@
kn-keyword=’´‰¹”g‘–�¸–@
en-keyword=ƒnƒEƒXƒ_ƒXƒg
kn-keyword=ƒnƒEƒXƒ_ƒXƒg
en-keyword=‹CŠÇŽxšb‘§
kn-keyword=‹CŠÇŽxšb‘§
END

start-ver=1.4
cd-journal=joma
no-vol=3
cd-vols=
no-issue=1
article-no=
start-page=43
end-page=46
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960920
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Sulfur isotope ratios of some Roseki deposits in the Inner Zone of Southwest Japan
kn-title=�¼“ì“ú–{“à‘т̂낤�Î�z�°‚Ì—°‰©“¯ˆÊ‘Ì”ä
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Sulfur isotope ratios of pyrite and alunite from 5 Roseki deposits in the Inner Zone of Southwest Japan were determined. The ƒÂ34S values of all pyrite samples were in the range from -13.2 to +2.3%, the variation range for each deposit being within 8%. In each deposit ƒÂ34S values of alunite were always higher than those of pyrite, which may be interpreted as that alunite was precipirated under more oxidizing conditions than pyrite. Sulfur isotope rations of the Roseki pyrite showed a distribution similar to that of ore sulfur from skarn and vein deposits in the same Zone. This suggests that the origin of sulfur of the Roseki deposits is also host igneous rocks.
en-copyright=
kn-copyright=

en-aut-name=YamamotoMasahiro
en-aut-sei=Yamamoto
en-aut-mei=Masahiro
kn-aut-name=ŽR–{‰ë�O
kn-aut-sei=ŽR–{
kn-aut-mei=‰ë�O
aut-affil-num=1
ORCID=

en-aut-name=MatsudaToshihiko
en-aut-sei=Matsuda
en-aut-mei=Toshihiko
kn-aut-name=�¼“c•q•F
kn-aut-sei=�¼“c
kn-aut-mei=•q•F
aut-affil-num=2
ORCID=

en-aut-name=NakagawaRaiki
en-aut-sei=Nakagawa
en-aut-mei=Raiki
kn-aut-name=’†�ì—Š‹L
kn-aut-sei=’†�ì
kn-aut-mei=—Š‹L
aut-affil-num=3
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw—�Šw•”’n‹…‰ÈŠw‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠw—�Šw•”’n‹…‰ÈŠw‰È

affil-num=3
en-affil=
kn-affil=Š”Ž®‰ïŽÐƒˆ�[ƒ^ƒC
en-keyword=sulfur isotope ratio
kn-keyword=sulfur isotope ratio
en-keyword=Roseki deposit
kn-keyword=Roseki deposit
en-keyword=pyrite
kn-keyword=pyrite
en-keyword=alunite
kn-keyword=alunite
END

start-ver=1.4
cd-journal=joma
no-vol=105
cd-vols=
no-issue=1-2
article-no=
start-page=35
end-page=41
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1993
dt-pub=19930227
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Operative morbidity of elderly patients with gastrointestinal disease
kn-title=�‚—îŽÒ�Á‰»ŠíŽè�p‚É‚¨‚¯‚é�pŒã�‡•¹�Ç
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The operative morbidity and its relating factors were studied on 95 patients, 80 years old or older, operated for gastrointestinal (GI) diseases under general anesthesia at the department in a recent 11-year period. Among a total of 98 cases of GI diseases including 32 of gastric cancer, 17 of colorectal cancer, 16 of cholelithiasis and 33 of others, 108 procedures were performed for 38 gastric, 27 colorectal, 31 hepato-biliary-pancreatic and 12 other surgical conditions. Fifty-four operative complications occurred in 39 cases(41%), which were 13 respiratory, 11 delirium, 9 cardiovascular and 21 other complications. The respiratory morbidity rate was significantly high in males and significantly low in the cases receiving halanced epidural anesthesia. Postoperative delirium occurred more frequently in patients having an intraoperative blood loss of over 200 ml, and the cardiovascular morbidity rate was significantly high for an operative time of over 3 hours. The operative morbidity and 30-day operative mortality rate were significantly higher for emergency operations than for non-emergency operations. These findings suggest that, in the surgery for elderly patients and especially in an emergent situation, special care must be paid to decrease the quantity of bleeding and shorten the duration of operation by employing a proper procedure and anesthesia.
en-copyright=
kn-copyright=

en-aut-name=ShiikiShigeo
en-aut-sei=Shiiki
en-aut-mei=Shigeo
kn-aut-name=’Å–ØŽ —Y
kn-aut-sei=’Å–Ø
kn-aut-mei=Ž —Y
aut-affil-num=1
ORCID=

en-aut-name=NakagawaKazuhiro
en-aut-sei=Nakagawa
en-aut-mei=Kazuhiro
kn-aut-name=’†�ì˜a•F
kn-aut-sei=’†�ì
kn-aut-mei=˜a•F
aut-affil-num=2
ORCID=

en-aut-name=SasakiHiroshi
en-aut-sei=Sasaki
en-aut-mei=Hiroshi
kn-aut-name=�²�X–ØŠ°
kn-aut-sei=�²�X–Ø
kn-aut-mei=Š°
aut-affil-num=3
ORCID=

en-aut-name=YamashitaYutaka
en-aut-sei=Yamashita
en-aut-mei=Yutaka
kn-aut-name=ŽR‰º—T
kn-aut-sei=ŽR‰º
kn-aut-mei=—T
aut-affil-num=4
ORCID=

en-aut-name=YumuraMasahito
en-aut-sei=Yumura
en-aut-mei=Masahito
kn-aut-name=“’‘º�³�m
kn-aut-sei=“’‘º
kn-aut-mei=�³�m
aut-affil-num=5
ORCID=

en-aut-name=KodaniJohji
en-aut-sei=Kodani
en-aut-mei=Johji
kn-aut-name=�¬’J�õŽ¡
kn-aut-sei=�¬’J
kn-aut-mei=�õŽ¡
aut-affil-num=6
ORCID=

en-aut-name=YunokiYasuhiro
en-aut-sei=Yunoki
en-aut-mei=Yasuhiro
kn-aut-name=—M–Ø–õ�O
kn-aut-sei=—M–Ø
kn-aut-mei=–õ�O
aut-affil-num=7
ORCID=

en-aut-name=OritaKunzo
en-aut-sei=Orita
en-aut-mei=Kunzo
kn-aut-name=�Ü“cŒOŽO
kn-aut-sei=�ܓc
kn-aut-mei=ŒOŽO
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=’¹ŽæŽs—§•a‰@ŠO‰È

affil-num=2
en-affil=
kn-affil=’¹ŽæŽs—§•a‰@ŠO‰È

affil-num=3
en-affil=
kn-affil=’¹ŽæŽs—§•a‰@ŠO‰È

affil-num=4
en-affil=
kn-affil=’¹ŽæŽs—§•a‰@ŠO‰È

affil-num=5
en-affil=
kn-affil=’¹ŽæŽs—§•a‰@ŠO‰È

affil-num=6
en-affil=
kn-affil=’¹ŽæŽs—§•a‰@ŠO‰È

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº
en-keyword=�‚—îŽÒ
kn-keyword=�‚—îŽÒ
en-keyword=�Á‰»ŠíŽè�p
kn-keyword=�Á‰»ŠíŽè�p
en-keyword=�pŒã�‡•¹�Ç
kn-keyword=�pŒã�‡•¹�Ç
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=9-10
article-no=
start-page=947
end-page=962
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=199410
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Low dose melphalan for myelodysplastic syndrome
kn-title=�œ�‘ˆÙŒ`�¬�ÇŒóŒQ‚É‚¨‚¯‚é melphalan �­—ʗÖ@‚ÌŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Myelodysplastic syndrome (MDS) is a disorder of multipotential hematopoietic stem cells. There is no effective therapy for MDS, especially for MDS associated with an excess of blasts, such as refractory anemia with excess blasts (RAEB) or RAEB in transformation (RAEBt). We previously reported the effect of K-18 (a human IgG-melphalan conjugate) in 15 patients with RAEB or RAEBt. The overall response rate was not high, but no side effects were noted. Although the mode of action of K-18 is not certain, it was suggested that the effect was associated with the activity of melpahlan itself. Therefore, low-dose melphalan therapy was initiated in eldery patients with RAEB or RAEBt. Six patients with RAEB and 12 patients with RAEBt received 2mg oral administration daily. Median age of the patients was 64. Six patients achieved complete remission (CR), one patient showed a partial response and four patients had a minor response. Total dosage of melpahlan for patients who achieved CR was 143�}18 mg. Median duration of CR was 14.5 months. Serious toxicity was not encountered in any case and neither marrow suppression nor pancytopenia were observed in cases that achieved CR during the administration of melphalan. Changes in cell surface markers (CD34, CD33, CD13) were examined during the time course of CR in two cases. CD34 + cells decreased rapidly during the first two weeks and CD34-CD33+cells increased after four weeks of melpahlan administration. Studying the clinical course of CR with cell surface marker analysis provided evidence that melphalan therapy induced differentiation of transformed hemopoietic precursors.
We conclude that daily chronic administration of melpahlan is a useful therapy for elderly patients with RAEB or RAEBt.
en-copyright=
kn-copyright=

en-aut-name=TakabaSeiji
en-aut-sei=Takaba
en-aut-mei=Seiji
kn-aut-name=�‚�ê�¬Ž¡
kn-aut-sei=�‚�ê
kn-aut-mei=�¬Ž¡
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æ“ñ“à‰ÈŠw‹³Žº
en-keyword=RAEB
kn-keyword=RAEB
en-keyword=RAEBt
kn-keyword=RAEBt
en-keyword=low dose melpahlan therapy
kn-keyword=low dose melpahlan therapy
en-keyword=CD34
kn-keyword=CD34
en-keyword=CD33
kn-keyword=CD33
END

start-ver=1.4
cd-journal=joma
no-vol=109
cd-vols=
no-issue=1-2
article-no=
start-page=7
end-page=14
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Choroidal arteriole changes after experimental destruction of the outer layer of the retina
kn-title=ŽÀŒ±“I–Ô–ŒŠO‘w�áŠQƒ‚ƒfƒ‹‚Ì–¬—�–ŒŒŒŠÇ‚̕ω»
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The purpose of the present study is to clarify the changes of choroidal circulation developing in the selective injuries of the outer layer of the retina. One, 2, 3 weeks and 3 months after intravenous administration of Monoiodoacetic acid in the rabbits, choroidal vessels were observed using indocyanine green angiography (ICG). The diameter of retinal arterioles decreased significantly at 3 weeks and 3 months after the treatment and hypofluorescence in the background was observed at 3 months. Histological examination revealed significant decrease in choriocapillaris at 3 weeks, a thickening of the endothelial cytoplasma and a disappearance of fenestration in choriocapillaris after 3 months. These histological findings were considered to be a cause of hypofluorescence of background in ICG. The results suggest that the selective damage of the outer layer of the retina induce changes in the choroidal circulation.
en-copyright=
kn-copyright=

en-aut-name=FujikawaEtsuko
en-aut-sei=Fujikawa
en-aut-mei=Etsuko
kn-aut-name=“¡�삦‚‚±
kn-aut-sei=“¡�ì
kn-aut-mei=‚¦‚‚±
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”Šá‰ÈŠw‹³Žº
en-keyword=–Ô–ŒŠO‘w�áŠQ
kn-keyword=–Ô–ŒŠO‘w�áŠQ
en-keyword=–¬—�–Œ�zŠÂ
kn-keyword=–¬—�–Œ�zŠÂ
en-keyword=ƒ‚ƒmƒˆ�[ƒh�|Ž_
kn-keyword=ƒ‚ƒmƒˆ�[ƒh�|Ž_
en-keyword=ƒCƒ“ƒhƒVƒAƒjƒ“ƒOƒŠ�[ƒ“ŒuŒõŠá’ê‘¢‰e
kn-keyword=ƒCƒ“ƒhƒVƒAƒjƒ“ƒOƒŠ�[ƒ“ŒuŒõŠá’ê‘¢‰e
END

start-ver=1.4
cd-journal=joma
no-vol=108
cd-vols=
no-issue=3-6
article-no=
start-page=155
end-page=159
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960629
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Laparoscopic cholecystectomy in 3 cases of hemodialysis patients
kn-title=“§�ÍŠ³ŽÒ‚É‚¨‚¯‚é• �o‹¾‰º’_?“E�o�p‚ÌŒoŒ±
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Laparoscopic cholecystectomy has proven to be a safe and effective treatment for symptomatic gall stone disease. However, laparoscopic cholecystectomy in hemodialysis patients is considered to be relatively contraindicated because of anemia and bleeding tendency. We performed laparoscopic cholecystectomy in three patients being treated by hemodialysis for chronic renal failure. No significant complications were observed after surgery. Laparoscopic cholecystectomy should be considered for hemodialysis patients requiring cholecystectomy.
en-copyright=
kn-copyright=

en-aut-name=TakaiKenichi
en-aut-sei=Takai
en-aut-mei=Kenichi
kn-aut-name=�‚ˆäŒ¤ˆê
kn-aut-sei=�‚ˆä
kn-aut-mei=Œ¤ˆê
aut-affil-num=1
ORCID=

en-aut-name=TaniaiKazuhi
en-aut-sei=Taniai
en-aut-mei=Kazuhi
kn-aut-name=’J�‡ˆê—z
kn-aut-sei=’J�‡
kn-aut-mei=ˆê—z
aut-affil-num=2
ORCID=

en-aut-name=TakatoriKatsuhiko
en-aut-sei=Takatori
en-aut-mei=Katsuhiko
kn-aut-name=�‚Žæ�Ž•F
kn-aut-sei=�‚Žæ
kn-aut-mei=�Ž•F
aut-affil-num=3
ORCID=

en-aut-name=OhtaSachiko
en-aut-sei=Ohta
en-aut-mei=Sachiko
kn-aut-name=‘å“c�ËŽq
kn-aut-sei=‘å“c
kn-aut-mei=�ˎq
aut-affil-num=4
ORCID=

en-aut-name=KunitomiMie
en-aut-sei=Kunitomi
en-aut-mei=Mie
kn-aut-name=�‘•xŽOŠG
kn-aut-sei=�‘•x
kn-aut-mei=ŽOŠG
aut-affil-num=5
ORCID=

en-aut-name=MatsuokaJunji
en-aut-sei=Matsuoka
en-aut-mei=Junji
kn-aut-name=�¼‰ª�‡Ž¡
kn-aut-sei=�¼‰ª
kn-aut-mei=�‡Ž¡
aut-affil-num=6
ORCID=

en-aut-name=KuroseMasao
en-aut-sei=Kurose
en-aut-mei=Masao
kn-aut-name=�•�£ú‹—Y
kn-aut-sei=�•�£
kn-aut-mei=ú‹—Y
aut-affil-num=7
ORCID=

en-aut-name=KojimaKazushi
en-aut-sei=Kojima
en-aut-mei=Kazushi
kn-aut-name=�¬“‡ˆêŽu
kn-aut-sei=�¬“‡
kn-aut-mei=ˆêŽu
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR’†‰›•a‰@“à‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR’†‰›•a‰@“à‰È

affil-num=3
en-affil=
kn-affil=‰ªŽR’†‰›•a‰@“à‰È

affil-num=4
en-affil=
kn-affil=‰ªŽR’†‰›•a‰@“à‰È

affil-num=5
en-affil=
kn-affil=‰ªŽR’†‰›•a‰@“à‰È

affil-num=6
en-affil=
kn-affil=‰ªŽR’†‰›•a‰@ŠO‰È

affil-num=7
en-affil=
kn-affil=‰ªŽR’†‰›•a‰@ŠO‰È

affil-num=8
en-affil=
kn-affil=‰ªŽR’†‰›•a‰@ŠO‰È
en-keyword=• �o‹¾‰º’_?“E�o�p
kn-keyword=• �o‹¾‰º’_?“E�o�p
en-keyword=“§�Í
kn-keyword=“§�Í
END

start-ver=1.4
cd-journal=joma
no-vol=108
cd-vols=
no-issue=3-6
article-no=
start-page=139
end-page=144
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960629
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Radioprotective effect of epinephrine as a vasoconstrictor in mouse oral mucosa and scalp
kn-title=ƒ}ƒEƒXŒû�o”S–Œ‚¨‚æ‚Ñ“ª•””畆‚ɑ΂·‚錌ŠÇŽû�k�܃GƒsƒlƒtƒŠƒ“‚Ì•úŽË�ü–hŒìŒø‰Ê‚ÌŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Epinephrine is the most widely used vasoconstrictive drug. However, its radioprotective potential has not yet been studied for radiation-induced mucositis and dermatitis. Other vasoconstrictive drugs induce a radioprotective effect, but are not used because of their severe side effects. We studied the radioprotective effect of epinephrine on the oral mucosa and scalp of the mice. The radiation dose was 20Gy in a single fraction to the head of the mouse. In the group treated with epinephrine ointment, secretion from the oral cavity was slight, body wieght loss was less and hair loss was observed in fewer cases compared to those in the group without of epinephrine ointment. The mechanism is thought to be related to oxygenation. Epinephrine causes vasoconstriction, therefore the blood supply is lowered and the oxygen concentration in the tissue decline. In conclusion, epinephrine is considered to have potential as a radioprotective ointment for mucous membranes and skin.
en-copyright=
kn-copyright=

en-aut-name=GaoXianshu
en-aut-sei=Gao
en-aut-mei=Xianshu
kn-aut-name=�‚Œ£�‘
kn-aut-sei=�‚
kn-aut-mei=Œ£�‘
aut-affil-num=1
ORCID=

en-aut-name=NakagawaTomio
en-aut-sei=Nakagawa
en-aut-mei=Tomio
kn-aut-name=’†�ì•x•v
kn-aut-sei=’†�ì
kn-aut-mei=•x•v
aut-affil-num=2
ORCID=

en-aut-name=YamamotoMichinori
en-aut-sei=Yamamoto
en-aut-mei=Michinori
kn-aut-name=ŽR–{“¹–@
kn-aut-sei=ŽR–{
kn-aut-mei=“¹–@
aut-affil-num=3
ORCID=

en-aut-name=KurodaMasahiro
en-aut-sei=Kuroda
en-aut-mei=Masahiro
kn-aut-name=�•“c�¹�G
kn-aut-sei=�•“c
kn-aut-mei=�¹�G
aut-affil-num=4
ORCID=

en-aut-name=SakaeKatsuyoshi
en-aut-sei=Sakae
en-aut-mei=Katsuyoshi
kn-aut-name=‰h�Ÿ”ü
kn-aut-sei=‰h
kn-aut-mei=�Ÿ”ü
aut-affil-num=5
ORCID=

en-aut-name=ShimizuMitsuharu
en-aut-sei=Shimizu
en-aut-mei=Mitsuharu
kn-aut-name=�´�…Œõ�t
kn-aut-sei=�´�…
kn-aut-mei=Œõ�t
aut-affil-num=6
ORCID=

en-aut-name=NiiyaHarutaka
en-aut-sei=Niiya
en-aut-mei=Harutaka
kn-aut-name=�V‰®�°�F
kn-aut-sei=�V‰®
kn-aut-mei=�°�F
aut-affil-num=7
ORCID=

en-aut-name=TakedaYoshihiro
en-aut-sei=Takeda
en-aut-mei=Yoshihiro
kn-aut-name=’|“c–F�O
kn-aut-sei=’|“c
kn-aut-mei=–F�O
aut-affil-num=8
ORCID=

en-aut-name=JojaIkuo
en-aut-sei=Joja
en-aut-mei=Ikuo
kn-aut-name=�ãŽÒˆè•v
kn-aut-sei=�ãŽÒ
kn-aut-mei=ˆè•v
aut-affil-num=9
ORCID=

en-aut-name=HirakiYoshio
en-aut-sei=Hiraki
en-aut-mei=Yoshio
kn-aut-name=•½–Ø�Ë•v
kn-aut-sei=•½–Ø
kn-aut-mei=�˕v
aut-affil-num=10
ORCID=

en-aut-name=KawasakiShoji
en-aut-sei=Kawasaki
en-aut-mei=Shoji
kn-aut-name=�ì�è�Ë“ñ
kn-aut-sei=�ì�è
kn-aut-mei=�Ë“ñ
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽË�üˆãŠw‹³Žº

affil-num=11
en-affil=
kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”�f—ÕúŽË�ü‹Z�pŠw‰È
en-keyword=ƒGƒsƒlƒtƒŠƒ“
kn-keyword=ƒGƒsƒlƒtƒŠƒ“
en-keyword=•úŽË�ü–hŒì�Ü
kn-keyword=•úŽË�ü–hŒì�Ü
en-keyword=ŒŒŠÇŽû�k
kn-keyword=ŒŒŠÇŽû�k
en-keyword=Ž_‘fŒø‰Ê
kn-keyword=Ž_‘fŒø‰Ê
en-keyword=ƒ}ƒEƒX”S–Œ”畆
kn-keyword=ƒ}ƒEƒX”S–Œ”畆
END

start-ver=1.4
cd-journal=joma
no-vol=108
cd-vols=
no-issue=3-6
article-no=
start-page=129
end-page=137
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960629
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Suppression of liver metastasis by biological response modifiers (BRMs) and the significance of local immunity in the liver
kn-title=Biological response modifier (BRM) ‚É‚æ‚éŠÌ“]ˆÚ—}�§‚ÆŠÌ‹Ç�Š–Ɖu‚ÉŠÖ‚·‚錤‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Efficacy of a combination therapy with two biological response modifiers (BRMs), oral PSK and systemic IL-2, was evaluated in a mouse model system of hepatic metastasis from colon cancer. Hepatic metastasis was significantly suppressed and the duration of survival was significantly prolonged by combination therapy, but not by either therapy alone. The therapeutic effects were attributable to the mechanism that non-MHC restricted cytotoxicity of hepatic non-parenchymal lymphocytes activated by IL-2 was augmented by PSK-activated Kupffer cells with direct cell-to-cell contact. These results suggest that local immunity in the liver plays an important role in the formation and development of hepatic metastasis and that the combination of these two BRMs may provide an effective new clinical therapy.
en-copyright=
kn-copyright=

en-aut-name=TakahashiMasahiko
en-aut-sei=Takahashi
en-aut-mei=Masahiko
kn-aut-name=�‚‹´�³•F
kn-aut-sei=�‚‹´
kn-aut-mei=�³•F
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰È‹³Žº
en-keyword=ŠÌˆÚ“]
kn-keyword=ŠÌˆÚ“]
en-keyword=ŠÌƒŠƒ“ƒp‹…
kn-keyword=ŠÌƒŠƒ“ƒp‹…
en-keyword=ƒNƒbƒp�[�×–E
kn-keyword=ƒNƒbƒp�[�×–E
en-keyword=PSK
kn-keyword=PSK
en-keyword=interleukin 2 (IL-2)
kn-keyword=interleukin 2 (IL-2)
END

start-ver=1.4
cd-journal=joma
no-vol=108
cd-vols=
no-issue=3-6
article-no=
start-page=83
end-page=95
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960629
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Comparison of postoperative circulatory, respiratory and immunological parameters between one-stage and two-stage surgery of intrathoracic esophageal carcinoma
kn-title=�zŠÂ�CŒÄ‹z�C–Ɖu“®‘Ô‚æ‚è‚Ý‚½‹¹•”�H“¹Šà‚ɑ΂·‚é1Šú“IŽè�p‚Æ•ªŠ„Žè�p‚Æ‚Ì”äŠrŒŸ“¢
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=There are two major surgical procedures for excision of esophageal carcinoma and reconstruction of the esophagus: the one-stage procedure and the two-stage procedure. In the present study, we evaluated the two methods by comparing the cardiovascular, respiratory and immune parameters of 10 patients who underwent one-stage procedure with those of 10 other patients who underwent two-stage procedure. To estimate cardiovascular function, we measured the left ventricular stroke work index (LVSWI)-pulmonary capillary wedge pressure (PCWP). Most of the patients treated by the one-stage procedure showed a significant decrease in LVSWI-PCWP, whereas the index of patients treated by the two-stage procedure did not change much. When we assessed the respiratory system by forced vital capacity (FVC) and peak expiratory flow (PEF), the patients treated by the two-stage procedure recovered much faster and better than those receiving the one-stage procedure. Natural killer (NK) activity in lymphocytes was also measured as a marker of the immuno-reactive system. Although most patients show a drop in NK activity one week after major surgery, NK activity did not demonstrate a significant change in any of the patients who underwent the two-stage procedume. Thus, our systemic comparison of the three different parameters demonstrated better results after the two-stage procedure and we recommend it over the one-stage procedure, especially for aged and high risk patients.
en-copyright=
kn-copyright=

en-aut-name=MuramatsuTomoyoshi
en-aut-sei=Muramatsu
en-aut-mei=Tomoyoshi
kn-aut-name=‘º�¼—F‹`
kn-aut-sei=‘º�¼
kn-aut-mei=—F‹`
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‘æˆêŠO‰ÈŠw‹³Žº
en-keyword=intrathoracic esophageal carcinoma
kn-keyword=intrathoracic esophageal carcinoma
en-keyword=one-stage procedure
kn-keyword=one-stage procedure
en-keyword=two-stage procedure
kn-keyword=two-stage procedure
en-keyword=reduction of operative stress
kn-keyword=reduction of operative stress
END

start-ver=1.4
cd-journal=joma
no-vol=111
cd-vols=
no-issue=3-8
article-no=
start-page=95
end-page=104
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Stress raises intraocular pressure in rabbits
kn-title=ƒXƒgƒŒƒX‚ªŠáˆ³‚É—^‚¦‚é‰e‹¿
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Purpose. To test whether encagement and volume load as stressors influence the intraocular pressure in rabbits.
Method. Rabbits were encaged for an hour in a horizontally-plastic tube with an internal diameter of 13.2 cm and a length of 33.2cm. After the encagement, rabbits received a rapid intraveonus drip infusion of 5% glucose solution, 20 ml per kilogram of body weight, for 5-6 minutes. All experiments were performed at the same time of day.
Results. The intraocular pressure after encagement (11.2�}3.0mmHg as a mean and standard deviation) was significantly higher compared with that of control rabbits without encagement (9.2�}1.0mmHg, Student t-test,p=0.046). This differnce became signifficantly larger when volume load was exerted on both groups of rabbits (p=0.0007). Serum levels of cortisol, adrenaline, and nordrenaline were significantly elevated afte encagement (n=6, p=0.0002, p=0.027, p=0.030, respectively). Venous pressure of the ear tended to increase in rabbits after encagement (15.8�}3.1mmHg) compared with that of control rabbits (8.5�}2.3mmHg,p=0.11), and the difference became significant when volume load was placed on each group of rabbits (p=0.021).
Conclusions.Encagement, especially in combination with volume losd, increased the intraocular pressure in rabbits. The elevation of peripheral venous pressure caused by an increase in serum catecholamines would underlie the elevation of intraocular pressure proh-ably through the increased outflow resistance.
en-copyright=
kn-copyright=

en-aut-name=MiyazakiYoshinori
en-aut-sei=Miyazaki
en-aut-mei=Yoshinori
kn-aut-name=‹{ú±‹`‘¥
kn-aut-sei=‹{ú±
kn-aut-mei=‹`‘¥
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”Šá‰ÈŠw�u�À
en-keyword=stress
kn-keyword=stress
en-keyword=intraocular pressure
kn-keyword=intraocular pressure
en-keyword=cortisol
kn-keyword=cortisol
en-keyword=catecholamines
kn-keyword=catecholamines
en-keyword=venus pressure
kn-keyword=venus pressure
END

start-ver=1.4
cd-journal=joma
no-vol=112
cd-vols=
no-issue=3-8
article-no=
start-page=39
end-page=46
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2000
dt-pub=20000831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The effects of health services facilities on medical expenditure for the elderly
kn-title=˜V�l•ÛŒ’Ž{�Ý‚ª˜V�lˆã—Ôï‚É—^‚¦‚é‰e‹¿‚ɂ‚¢‚Ä
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The first Health Services Facility was started in 1988, to provide the elderly with medical care services in Japan. The facilities have encouraged home care and their numbers have been increasing rapidly. In order to examine the effects of the facilities on medical expenditure for the elderly, cross-sectional and follow-up surveys were conducted with epidemiological analyses of the data from all 47 prefectures in 1990, 1993 and 1996. Multiple regression models were performed using several costs that used medical expenditure for the elderly as the explanatory variables. Furthermore, correlation coefficients between the changes in admission rates, duration of hospitalization, and the change of the numbers of beds in the facilities were calculated. The results are as follows. 1) There was a positive correlation between the cost of the facilities and medical expenditure for the elderly, but the effects have been decreasing with increased construction. 2) There was no relationship between the numbers of beds in the facilities and admission rate to the hospitals, but there was a correlation with the duration of hospitalization.
en-copyright=
kn-copyright=

en-aut-name=OhtsuTadahiro
en-aut-sei=Ohtsu
en-aut-mei=Tadahiro
kn-aut-name=‘å’Ã’‰�O
kn-aut-sei=‘å’Ã
kn-aut-mei=’‰�O
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”‰q�¶Šw�u�À
en-keyword=˜V�l•ÛŒ’Ž{�Ý
kn-keyword=˜V�l•ÛŒ’Ž{�Ý
en-keyword=˜V�lˆã—Ôï
kn-keyword=˜V�lˆã—Ôï
en-keyword=“ü‰@Žó�f—¦
kn-keyword=“ü‰@Žó�f—¦
en-keyword=“ü‰@“ú�”
kn-keyword=“ü‰@“ú�”
END

start-ver=1.4
cd-journal=joma
no-vol=114
cd-vols=
no-issue=3
article-no=
start-page=289
end-page=296
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=20030131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of phospholipase A(2) on proliferation of the primary cultured biliary epithelial cells from the extra-hepatic bile duct to rats using D-valine containing medium
kn-title=D-ƒoƒŠƒ“”|’n–@‚É‚æ‚è‘I‘ð“I‚É�‰‘ã”|—{‚µ‚½ƒ‰ƒbƒg’_ŠÇ�ã”ç�×–E‚ɑ΂·‚é Phospholipase A(2) ‚Ì�×–E‘��B‘£�iŒø‰Ê‚̉ð�Í
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We hypothesized that a high level of phospholipase A(2) (PLA(2)) in bile juice works as a growth factor of biliary epithelial cells and causes hyperplastic change of the bile duct in pancreaticobiliary maljunction. in order to examine this hypothesis, we established a primary culture system of biliary epithelial cells from the extra-hepatic bile duct of rats. We successfully excluded fibroblasts from the epithelial cells using D-valine-containing medium and the single-cell cloning method. The established cells exhibited the characteristic features of rat bile duct epithelial cells. They were stained with anti-cytokeratin antibody, a marker protein of epithelial cells, were positive with PAS stain, and possessed the architectures of microvilli, tonofilament fibers and desmosomes. The effect of PLA(2) on proliferation of these cells was then examined. We clearly demonstrated that PLA(2) at nano-molar concentration (50nM, 100nM), that is, equivalent to the level of PLA(2) in the bile juice of pancreaticobiliary maljunction cases, caused a significant enhancement of epithelial cell proliferation.
en-copyright=
kn-copyright=

en-aut-name=OguraKaoru
en-aut-sei=Ogura
en-aut-mei=Kaoru
kn-aut-name=�¬‘qŒO
kn-aut-sei=�¬‘q
kn-aut-mei=ŒO
aut-affil-num=1
ORCID=

en-aut-name=WatanabeYasuhiro
en-aut-sei=Watanabe
en-aut-mei=Yasuhiro
kn-aut-name=“n•Ó‘×�G
kn-aut-sei=“n•Ó
kn-aut-mei=‘×�G
aut-affil-num=2
ORCID=

en-aut-name=HiramineChiharu
en-aut-sei=Hiramine
en-aut-mei=Chiharu
kn-aut-name=•½•õ�ç�t
kn-aut-sei=•½•õ
kn-aut-mei=�ç�t
aut-affil-num=3
ORCID=

en-aut-name=NakagawaToshitaka
en-aut-sei=Nakagawa
en-aut-mei=Toshitaka
kn-aut-name=’†�ì—˜�F
kn-aut-sei=’†�ì
kn-aut-mei=—˜�F
aut-affil-num=4
ORCID=

en-aut-name=TokiAkira
en-aut-sei=Toki
en-aut-mei=Akira
kn-aut-name=“yŠò�²
kn-aut-sei=“yŠò
kn-aut-mei=�²
aut-affil-num=5
ORCID=

en-aut-name=TokudaMasaaki
en-aut-sei=Tokuda
en-aut-mei=Masaaki
kn-aut-name=“¿“c‰ë–¾
kn-aut-sei=“¿“c
kn-aut-mei=‰ë–¾
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=���ìˆã‰È‘åŠw�¬Ž™ŠO‰ÈŠw

affil-num=2
en-affil=
kn-affil=���ìˆã‰È‘åŠw�¬Ž™ŠO‰ÈŠw

affil-num=3
en-affil=
kn-affil=���ìˆã‰È‘åŠwŠî‘bŠÅŒìŠw

affil-num=4
en-affil=
kn-affil=���ìˆã‰È‘åŠw•�‘®ŽÀŒ±ŽÀ�K‹@ŠíƒZƒ“ƒ^�[

affil-num=5
en-affil=
kn-affil=���ìˆã‰È‘åŠw�¬Ž™ŠO‰ÈŠw

affil-num=6
en-affil=
kn-affil=���ìˆã‰È‘åŠw�¶—�Šw
en-keyword=äX�E’_ŠÇ�‡—¬ˆÙ�í
kn-keyword=äX�E’_ŠÇ�‡—¬ˆÙ�í
en-keyword=’_ŠÇ�ã”ç�×–E
kn-keyword=’_ŠÇ�ã”ç�×–E
en-keyword=D�|ƒoƒŠƒ“
kn-keyword=D�|ƒoƒŠƒ“
en-keyword=Phospholipase A(2)
kn-keyword=Phospholipase A(2)
en-keyword=�×–E‘��B
kn-keyword=�×–E‘��B
END

start-ver=1.4
cd-journal=joma
no-vol=115
cd-vols=
no-issue=2
article-no=
start-page=119
end-page=123
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of adult Meckel's diveticul um with gastrointestinal bleeding
kn-title=‰ºŒŒ‚ðŽå‘i‚Æ‚µ‚Ä”­Œ©‚³‚ꂽ�¬�l Meckel ŒeŽº‚É1—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Gastrointestinal bleeding is often intermittent and its souree may be difficult to locate, resulting in delay of definitve diagnosis. Melena usually denotes bleeding not only from the upper, and lower gastrointestine but from the small int estine. Adult Meckel's diverticulum with gastrointestinal beeding is a relatively rare disease and  often presents difficulty in preoperative diagnosis. A 65-year-old man was admitted to our hospital due to melena. Upper and lower gastrointestional endoscopy revealed no  bleeding stie. (99m)Tc-pertechnetate scintigraphy is well known as a useful tool for preoperative delineation of Meckel's diverticulm. (99m)Tc-pertechnetate scintigraphy was performed in this patient and succesfully depicted the lesion noninvasively. In surgery, Meckel's diverticulum was found at an oral stie 90 cm from the terminalileum, and a sleevereseection was performed. Histopathologically, the diver ticulum had ectopic gastric muco sa and two 5mm ulcers on the border of the gastric mucosa.
en-copyright=
kn-copyright=

en-aut-name=MorimotoYoshinori
en-aut-sei=Morimoto
en-aut-mei=Yoshinori
kn-aut-name=Žç–{–F“T
kn-aut-sei=Žç–{
kn-aut-mei=–F“T
aut-affil-num=1
ORCID=

en-aut-name=IwagakiHiromi
en-aut-sei=Iwagaki
en-aut-mei=Hiromi
kn-aut-name=ŠâŠ_”ŽŒÈ
kn-aut-sei=ŠâŠ_
kn-aut-mei=”ŽŒÈ
aut-affil-num=2
ORCID=

en-aut-name=MorishitaNorio
en-aut-sei=Morishita
en-aut-mei=Norio
kn-aut-name=�X‰º‹I•v
kn-aut-sei=�X‰º
kn-aut-mei=‹I•v
aut-affil-num=3
ORCID=

en-aut-name=NakagawaHitoshi
en-aut-sei=Nakagawa
en-aut-mei=Hitoshi
kn-aut-name=’†�ì�mŽu
kn-aut-sei=’†�ì
kn-aut-mei=�mŽu
aut-affil-num=4
ORCID=

en-aut-name=MatsubaraNagahide
en-aut-sei=Matsubara
en-aut-mei=Nagahide
kn-aut-name=�¼Œ´’·�G
kn-aut-sei=�¼Œ´
kn-aut-mei=’·�G
aut-affil-num=5
ORCID=

en-aut-name=IsozakiHiroshi
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en-aut-mei=Hiroshi
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kn-aut-mei=”ŽŽi
aut-affil-num=6
ORCID=

en-aut-name=KajiEisuke
en-aut-sei=Kaji
en-aut-mei=Eisuke
kn-aut-name=‰Á’n‰p•ã
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kn-aut-mei=‰p•ã
aut-affil-num=7
ORCID=

en-aut-name=OkadaHiroyuki
en-aut-sei=Okada
en-aut-mei=Hiroyuki
kn-aut-name=‰ª“c—T”V
kn-aut-sei=‰ª“c
kn-aut-mei=—T”V
aut-affil-num=8
ORCID=

en-aut-name=MizunoMotoo
en-aut-sei=Mizuno
en-aut-mei=Motoo
kn-aut-name=�…–쌳•v
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kn-aut-mei=Œ³•v
aut-affil-num=9
ORCID=

en-aut-name=ShiratoriYasushi
en-aut-sei=Shiratori
en-aut-mei=Yasushi
kn-aut-name=”’’¹�NŽj
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kn-aut-mei=�NŽj
aut-affil-num=10
ORCID=

en-aut-name=TnakaNoriaki
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en-aut-mei=Noriaki
kn-aut-name=“c’†‹I�Í
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kn-aut-mei=‹I�Í
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰È

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰È

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰È

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰È

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰È

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰È

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŠÌ‘Ÿ�EŠ´�õ�Ç“à‰ÈŠw

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŠÌ‘Ÿ�EŠ´�õ�Ç“à‰ÈŠw

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŠÌ‘Ÿ�EŠ´�õ�Ç“à‰ÈŠw

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŠÌ‘Ÿ�EŠ´�õ�Ç“à‰ÈŠw

affil-num=11
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•Šw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰È
en-keyword=‰ºŒŒ
kn-keyword=‰ºŒŒ
en-keyword=�¬�l
kn-keyword=�¬�l
en-keyword=MeckelŒeŽº
kn-keyword=MeckelŒeŽº
en-keyword=ˆÙ�Š�«ˆÝ”S–Œ
kn-keyword=ˆÙ�Š�«ˆÝ”S–Œ
en-keyword=99mTc-pertechnetateƒVƒ“ƒ`ƒOƒ‰ƒtƒB
kn-keyword=99mTc-pertechnetateƒVƒ“ƒ`ƒOƒ‰ƒtƒB
END

start-ver=1.4
cd-journal=joma
no-vol=117
cd-vols=
no-issue=3
article-no=
start-page=211
end-page=217
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2006
dt-pub=20060104
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=�œ“î•”Žîá‡�f’f‚ÆŽ¡—Âɂ¨‚¯‚é‹ß”N‚Ì�i•à
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
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kn-aut-sei=”öú±
kn-aut-mei=•q•¶
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È �®Œ`ŠO‰ÈŠw
en-keyword=�œ“î•”Žîá‡
kn-keyword=�œ“î•”Žîá‡
en-keyword=Ž¡—Ã
kn-keyword=Ž¡—Ã
en-keyword=�¶‘¶—¦
kn-keyword=�¶‘¶—¦
en-keyword=‹@”\�ÄŒš
kn-keyword=‹@”\�ÄŒš
END

start-ver=1.4
cd-journal=joma
no-vol=117
cd-vols=
no-issue=2
article-no=
start-page=97
end-page=103
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050901
dt-online=
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kn-subject=
en-title=
kn-title=‘å’°Šà‚É‚¨‚¯‚éKRAS�CBRAF ˆâ“`Žq“Ë‘R•ÏˆÙ‚ÆDNA ƒ�ƒ`ƒ‹‰»
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ORCID=

en-aut-name=
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ORCID=

en-aut-name=
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ORCID=

en-aut-name=
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kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=2
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affil-num=4
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affil-num=6
en-affil=
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affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=11
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=12
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=13
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=14
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=15
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�Á‰»Ší�EŽîᇊO‰ÈŠw
en-keyword=Colorectal Cancer
kn-keyword=Colorectal Cancer
en-keyword=MSI
kn-keyword=MSI
en-keyword=DNA Methylation
kn-keyword=DNA Methylation
en-keyword=KRAS mutation
kn-keyword=KRAS mutation
en-keyword=BRAF mutation
kn-keyword=BRAF mutation
END

start-ver=1.4
cd-journal=joma
no-vol=118
cd-vols=
no-issue=1
article-no=
start-page=41
end-page=45
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2006
dt-pub=20060501
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Two cases of acute pulmonary embolism after esophageal cancer operation
kn-title=‘�Šú�f’f‚µ“¾‚½�H“¹Šà�pŒã�Ö¬ŒŒ�ð�Ç�ð�Ç‚Ì2—á
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We encountered two cases of pulmonary embolism (PE)/venous thrombs (DVT) after surgery for esophageal cancer. The first case was a 58-year-old male. He underwent a subtotal esophagectomy and reconstruction using the stomach via the subcutaneus route. His postoperative course was stable; however, 13 days after the operation¤ he had an elevated fever and pulmonary thrombi were observed on CT-scan screening. Scintigraphy confirmed the thrombi. An inferior vena cava filter (IVCF) was inserted and anti-coagulation therapy using heparin was started. His fever subsided, and 35 days after the operation, the thrombi disappeared. He was discharged thereafter and is being followed up using warfarin. The second case was a 74-year-old male. He also underwent subtotal esophagectomy and reconstruction using the stomach via the subcutaneus route. A central line was inserted via right femoral vein; however, the artery was injured and pressurization to the vessel was needed. His post-operative course was stable and symptom-free; however, ultrasound screening detected DVT in his right femoral vein. IVCF was mserted and anti-coagulation therapy was begun, thrombi disappeared 8 days after the therapy.
en-copyright=
kn-copyright=

en-aut-name=KanazawaTakashi
en-aut-sei=Kanazawa
en-aut-mei=Takashi
kn-aut-name=‹ààV‘ì
kn-aut-sei=‹ààV
kn-aut-mei=‘ì
aut-affil-num=1
ORCID=

en-aut-name=WatababeNobuyuki
en-aut-sei=Watababe
en-aut-mei=Nobuyuki
kn-aut-name=“n•Ó�M”V
kn-aut-sei=“n•Ó
kn-aut-mei=�M”V
aut-affil-num=2
ORCID=

en-aut-name=NaomotoYoshio
en-aut-sei=Naomoto
en-aut-mei=Yoshio
kn-aut-name=—P–{—Ç•v
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kn-aut-mei=—Ç•v
aut-affil-num=3
ORCID=

en-aut-name=KobayashiMasahiko
en-aut-sei=Kobayashi
en-aut-mei=Masahiko
kn-aut-name=�¬—Ñ�³•F
kn-aut-sei=�¬—Ñ
kn-aut-mei=�³•F
aut-affil-num=4
ORCID=

en-aut-name=ShirakawaYasuhiro
en-aut-sei=Shirakawa
en-aut-mei=Yasuhiro
kn-aut-name=”’�ì–õ”Ž
kn-aut-sei=”’�ì
kn-aut-mei=–õ”Ž
aut-affil-num=5
ORCID=

en-aut-name=YamatsujiTomoki
en-aut-sei=Yamatsuji
en-aut-mei=Tomoki
kn-aut-name=ŽR’Ò’mŽ÷
kn-aut-sei=ŽR’Ò
kn-aut-mei=’mŽ÷
aut-affil-num=6
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en-aut-name=KobayashiNaoya
en-aut-sei=Kobayashi
en-aut-mei=Naoya
kn-aut-name=�¬—Ñ’¼�Æ
kn-aut-sei=�¬—Ñ
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en-aut-name=FujiwaraTohsiyoshi
en-aut-sei=Fujiwara
en-aut-mei=Tohsiyoshi
kn-aut-name=“¡Œ´�r‹`
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kn-aut-mei=�r‹`
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en-aut-name=MatsubaraNagahide
en-aut-sei=Matsubara
en-aut-mei=Nagahide
kn-aut-name=�¼Œ´’·�G
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en-aut-name=IwagakiHiromi
en-aut-sei=Iwagaki
en-aut-mei=Hiromi
kn-aut-name=ŠâŠ_”Ž–¤
kn-aut-sei=ŠâŠ_
kn-aut-mei=”Ž–¤
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ORCID=

en-aut-name=MatsuokaJunji
en-aut-sei=Matsuoka
en-aut-mei=Junji
kn-aut-name=�¼‰ª�‡Ž¡
kn-aut-sei=�¼‰ª
kn-aut-mei=�‡Ž¡
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ORCID=

en-aut-name=TanakaNoriaki
en-aut-sei=Tanaka
en-aut-mei=Noriaki
kn-aut-name=“c’†‹I�Í
kn-aut-sei=“c’†
kn-aut-mei=‹I�Í
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ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=11
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw

affil-num=12
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È�@�Á‰»Ší�EŽîᇊO‰ÈŠw
en-keyword=�H“¹Šà (esophageal cancer)
kn-keyword=�H“¹Šà (esophageal cancer)
en-keyword=”x�Ç�ð�Ç (pulmonary embolism)
kn-keyword=”x�Ç�ð�Ç (pulmonary embolism)
en-keyword=�[•”�Ö¬ŒŒ�ð�Ç (deep venous thrombs)
kn-keyword=�[•”�Ö¬ŒŒ�ð�Ç (deep venous thrombs)
END

start-ver=1.4
cd-journal=joma
no-vol=119
cd-vols=
no-issue=3
article-no=
start-page=267
end-page=272
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=20080104
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A collaborative approach to head and neck carcinoma for oral surgeons, head and neck surgeons, and plastic surgeons: The role of oral surgeons in two cases
kn-title=“ªèò•”Šà‚É‚¨‚¯‚鎨•@ˆô�A‰È, Œ`�¬ŠO‰È, Œû�oŠO‰È3‰È�‡“¯Žè�p‚̈Ӌ` : 2�Ç—á‚É‚¨‚¯‚éŒû�oŠO‰È‚Ì–ðŠ„‚ð’†�S‚É
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=There is a medical team approach used in many hospitals for oral cancer patients. The members are head & neck surgeons and plastic surgeons, or oral surgeons and plastic surgeons. However, in Japan, it is very difficult for oral surgeons to cooperate with head & neck surgeons, except in the case of extractions and oral health care, because both surgeons treat oral carcinomas and there is therefore a conflict in their scope of practice. We believe it desirable for head & neck surgeons to treat oral cancer patients with tumors extending to other regions, and oral surgeons should be in charge of occlusion in head and neck carcinomas. We treated two patients with oral carcinomas in collaboration with head and neck surgeons and plastic surgeons, with head & neck surgeons resecting the tumors, plastic surgeons reconstructing, and oral surgeons (dentists) taking charge of the occlusion for patients in the operating room. This collaboration resulted in patients having good position of the temporomandibular joint and occlusions after the operation. We therefore conclude that this collaborative team approach may be of benefit to the patients.
en-copyright=
kn-copyright=

en-aut-name=MizukawaNobuyoshi
en-aut-sei=Mizukawa
en-aut-mei=Nobuyoshi
kn-aut-name=�…�ì“W‹g
kn-aut-sei=�…�ì
kn-aut-mei=“W‹g
aut-affil-num=1
ORCID=

en-aut-name=TominagaSusumu
en-aut-sei=Tominaga
en-aut-mei=Susumu
kn-aut-name=•y‰i�i
kn-aut-sei=•y‰i
kn-aut-mei=�i
aut-affil-num=2
ORCID=

en-aut-name=KimataYoshihiro
en-aut-sei=Kimata
en-aut-mei=Yoshihiro
kn-aut-name=–،Ҍh—T
kn-aut-sei=–ØŒÒ
kn-aut-mei=Œh—T
aut-affil-num=3
ORCID=

en-aut-name=OnodaTomoo
en-aut-sei=Onoda
en-aut-mei=Tomoo
kn-aut-name=�¬–ì“c—F’j
kn-aut-sei=�¬–ì“c
kn-aut-mei=—F’j
aut-affil-num=4
ORCID=

en-aut-name=NomiyaShigenobu
en-aut-sei=Nomiya
en-aut-mei=Shigenobu
kn-aut-name=–ì‹{�d�M
kn-aut-sei=–ì‹{
kn-aut-mei=�d�M
aut-affil-num=5
ORCID=

en-aut-name=SugiyamaNarushi
en-aut-sei=Sugiyama
en-aut-mei=Narushi
kn-aut-name=�™ŽR�¬Žj
kn-aut-sei=�™ŽR
kn-aut-mei=�¬Žj
aut-affil-num=6
ORCID=

en-aut-name=KawamotoTomoaki
en-aut-sei=Kawamoto
en-aut-mei=Tomoaki
kn-aut-name=�ì–{’m–¾
kn-aut-sei=�ì–{
kn-aut-mei=’m–¾
aut-affil-num=7
ORCID=

en-aut-name=YamachikaEiki
en-aut-sei=Yamachika
en-aut-mei=Eiki
kn-aut-name=ŽR‹ß‰pŽ÷
kn-aut-sei=ŽR‹ß
kn-aut-mei=‰pŽ÷
aut-affil-num=8
ORCID=

en-aut-name=UenoTakaaki
en-aut-sei=Ueno
en-aut-mei=Takaaki
kn-aut-name=�A–ì�‚�Í
kn-aut-sei=�A–ì
kn-aut-mei=�‚�Í
aut-affil-num=9
ORCID=

en-aut-name=TakagiShin
en-aut-sei=Takagi
en-aut-mei=Shin
kn-aut-name=�‚–Ø�T
kn-aut-sei=�‚–Ø
kn-aut-mei=�T
aut-affil-num=10
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠwˆãŠw•”�EŽ•Šw•”•�‘®•a‰@ Œû�oŠO‰È�ÄŒšŒn

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Ž¨•@ˆô�A�E“ªèò•”ŠO‰ÈŠw

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Œ`�¬�ÄŒšŠO‰ÈŠw

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Ž¨•@ˆô�A�E“ªèò•”ŠO‰ÈŠw

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Ž¨•@ˆô�A�E“ªèò•”ŠO‰ÈŠw

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Œ`�¬�ÄŒšŠO‰ÈŠw

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Ž•Š{Œû�o‹@”\�ÄŒšŠO‰ÈŠw

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Ž•Š{Œû�o‹@”\�ÄŒšŠO‰ÈŠw

affil-num=9
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Ž•Š{Œû�o‹@”\�ÄŒšŠO‰ÈŠw

affil-num=10
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Ž•Š{Œû�o‹@”\�ÄŒšŠO‰ÈŠw
en-keyword=ƒ`�[ƒ€ˆã—à (medical team approach)
kn-keyword=ƒ`�[ƒ€ˆã—à (medical team approach)
en-keyword=“ªèò•”Šà (head and neck carcinoma)
kn-keyword=“ªèò•”Šà (head and neck carcinoma)
END

start-ver=1.4
cd-journal=joma
no-vol=119
cd-vols=
no-issue=2
article-no=
start-page=127
end-page=129
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2007
dt-pub=20070903
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=XAGE-1expression in non-small cell Lung cancer and antibody response in patients
kn-title=”ñ�¬�×–E”xŠà‚É‚¨‚¯‚éŠà�E�¸‘ƒ�RŒ´XAGE-1‚Ì”­Œ»‚ƖƉu‰ž“š‚̉ð�Í
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaKazuhiko
en-aut-sei=Nakagawa
en-aut-mei=Kazuhiko
kn-aut-name=’†�ì˜a•F
kn-aut-sei=’†�ì
kn-aut-mei=˜a•F
aut-affil-num=1
ORCID=

en-aut-name=NoguchiYuji
en-aut-sei=Noguchi
en-aut-mei=Yuji
kn-aut-name=–ìŒû—YŽi
kn-aut-sei=ГΞ
kn-aut-mei=—YŽi
aut-affil-num=2
ORCID=

en-aut-name=OkumuraHideo
en-aut-sei=Okumura
en-aut-mei=Hideo
kn-aut-name=‰œ‘º‰p—Y
kn-aut-sei=‰œ‘º
kn-aut-mei=‰p—Y
aut-affil-num=3
ORCID=

en-aut-name=SatoShuichiro
en-aut-sei=Sato
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en-aut-name=TanakaMotoyuki
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en-aut-name=Ali EldibAli Mohamed
en-aut-sei=Ali Eldib
en-aut-mei=Ali Mohamed
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kn-aut-sei=ƒAƒŠ�EƒGƒ‹ƒfƒBƒu ƒAƒŠ
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en-aut-name=YamashitaKazuki
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en-aut-name=TsunodaTsukasa
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en-aut-name=ShimizuNobuyoshi
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kn-aut-name=’†ŽRá͈ê
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affil-num=1
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kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È –ƉuŠw

affil-num=2
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kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È –ƉuŠw

affil-num=3
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kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È –ƉuŠw

affil-num=4
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kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È –ƉuŠw

affil-num=5
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kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È –ƉuŠw

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È –ƉuŠw

affil-num=7
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È –ƉuŠw

affil-num=8
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Žîá‡�E‹¹•”ŠO‰ÈŠw

affil-num=9
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kn-affil=‰ªŽR‘åŠwŽ©‘R�¶–½‰ÈŠwŒ¤‹†Žx‰‡ƒZƒ“ƒ^�[

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kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È –ƉuŠw

affil-num=11
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È •a—��E•a‘ÔŠw

affil-num=12
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È •a—��E•a‘ÔŠw

affil-num=13
en-affil=
kn-affil=�ì�èˆã‰È‘åŠw•�‘®•a‰@ �Á‰»ŠíŠO‰ÈŠw

affil-num=14
en-affil=
kn-affil=�ì�èˆã‰È‘åŠw•�‘®•a‰@ �Á‰»ŠíŠO‰ÈŠw

affil-num=15
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È Žîá‡�E‹¹•”ŠO‰ÈŠw

affil-num=16
en-affil=
kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘��‡Œ¤‹†‰È –ƉuŠw
en-keyword=XAGE-1b
kn-keyword=XAGE-1b
en-keyword=Šà�¸‘ƒ�RŒ´
kn-keyword=Šà�¸‘ƒ�RŒ´
en-keyword=”ñ�¬�×–E”xŠà
kn-keyword=”ñ�¬�×–E”xŠà
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=20080325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=CT index ‚ð—p‚¢‚½�i˜R“l‹¹‚ɑ΂·‚é�jNuss–@‚Ì•]‰¿
kn-title=Evaluation of the Nuss procedure using pre and postoperative CT index
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaYoshikiyo
en-aut-sei=Nakagawa
en-aut-mei=Yoshikiyo
kn-aut-name=’†�ì‰ê�´
kn-aut-sei=’†�ì
kn-aut-mei=‰ê�´
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=20080325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=HGF�EPGISˆâ“`Žq‚Ì‹Ç�Š“I‹¤“±“ü‚É‚æ‚é”ç•Ù�¶’…—¦‚ÌŒü�ã
kn-title=Improvement of survival of skin flaps by combined gene transfer of hepatocyte growth factor and prostacyclin synthase
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=NakagawaAya
en-aut-sei=Nakagawa
en-aut-mei=Aya
kn-aut-name=’†�ì�Ê
kn-aut-sei=’†�ì
kn-aut-mei=�Ê
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw
END

start-ver=1.4
cd-journal=joma
no-vol=13
cd-vols=
no-issue=1
article-no=
start-page=7
end-page=15
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=200803
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Statistical modeling for analysis of malaria epidemic behavior at Ishigaki�@Island
kn-title=�Ί_“‡‚É‚¨‚¯‚éƒ}ƒ‰ƒŠƒA—¬�s‰ð�Í‚Ì‚½‚ß‚Ì“�Œvƒ‚ƒfƒŠƒ“ƒO
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=It is necessary to consider a stochastic variability in modeling malaria epidemic behavior since the�@malaria infection  cycle essentially depends on stochastic elements. For this requirement, we need to construct an appropriate statistical model from available data in advance. In this report, we provide some statistical models for the analysis of malaria epidemic behavior at Ishigaki Island. These models can be used for recurrence of past malaria epidemic and prediction of future malaria epidemic at Ishigaki Island.
en-copyright=
kn-copyright=

en-aut-name=UekiMasao
en-aut-sei=Ueki
en-aut-mei=Masao
kn-aut-name=�A–Ø—D•v
kn-aut-sei=�A–Ø
kn-aut-mei=—D•v
aut-affil-num=1
ORCID=

en-aut-name=NakagawaYuuki
en-aut-sei=Nakagawa
en-aut-mei=Yuuki
kn-aut-name=’†�ì—SŠó
kn-aut-sei=’†�ì
kn-aut-mei=—SŠó
aut-affil-num=2
ORCID=

en-aut-name=FuedaKaoru
en-aut-sei=Fueda
en-aut-mei=Kaoru
kn-aut-name=“J“cŒO
kn-aut-sei=“J“c
kn-aut-mei=ŒO
aut-affil-num=3
ORCID=

en-aut-name=IshikawaHirofumi
en-aut-sei=Ishikawa
en-aut-mei=Hirofumi
kn-aut-name=�Î�ì—m•¶
kn-aut-sei=�Î�ì
kn-aut-mei=—m•¶
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw

affil-num=2
en-affil=
kn-affil=‰ªŽR‘åŠw

affil-num=3
en-affil=
kn-affil=‰ªŽR‘åŠw

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠw
en-keyword=Anopheles minimus,
kn-keyword=Anopheles minimus,
en-keyword=generalized liner model
kn-keyword=generalized liner model
en-keyword=Ishigaki Island
kn-keyword=Ishigaki Island
en-keyword=malaria epidemic behavior
kn-keyword=malaria epidemic behavior
en-keyword=prediction
kn-keyword=prediction
en-keyword=stochastic model
kn-keyword=stochastic model
END

start-ver=1.4
cd-journal=joma
no-vol=39
cd-vols=
no-issue=2
article-no=
start-page=57
end-page=67
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2007
dt-pub=200709
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Inflation and Announcement?Drift ?Discussion about the Inflation Illusion Hypothesis?
kn-title=ƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“‚ƃAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg �|ƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“�öŠo‰¼�à‚ÉŠÖ‚·‚錟“¢�|
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=–{�e‚Ì–Ú“I‚Í�C—˜‰v‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg�ipost?earnings?announcement?drift�j‚ð�à–¾‚·‚éˆê‚‚̉¼�à‚Å‚ ‚éƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“�öŠo‰¼�à�iinflation illusion hypothesis�j‚ɂ‚¢‚ÄŠTŠÏ‚µ‚È‚ª‚ç�C‚±‚̉¼�à‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg�ipost?announcement?drift�jŒ¤‹†‚É‚¨‚¯‚éˆÓ‹`‚ɂ‚¢‚Ä�lŽ@‚·‚邱‚Æ‚Å‚ ‚é�Bƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ÌŒŸ�Ø‚Í�C�à–±�î•ñ‚ÆŒˆŽZ”­•\Œã‚ÌŠ”‰¿‚Æ‚ÌŠÖ˜A�«‚ð”»’f‚·‚é�ã‚Å—LŒø‚Å‚ ‚邪�C‚»‚ÌŠÖ˜A�«‚ªƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“‚ÆŠÖŒW‚µ‚Ä‚¢‚é‚Æ‚¢‚¤‚±‚Æ‚Í�CƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“‚ª�¶‚¶‚Ä‚¢‚é�ê�‡‚Ì�à–±�î•ñ‚Ì—L—p�«‚ɂ‚¢‚Ä�lŽ@‚·‚é�ã‚Ŗ𗧂‚©‚à‚µ‚ê‚È‚¢�Bƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚Í�C�à–±�î•ñ‚ª”­•\‚³‚ꂽŒã�C�”ƒ–ŒŽŠÔ‚ɂ킽‚è�Cƒvƒ‰ƒX‚̃Tƒvƒ‰ƒCƒY‚ɑ΂µ‚ÄŠ”‰¿‚ªŽs�ꕽ‹Ï‚æ‚è‚à�ã�¸‚µ�Cƒ}ƒCƒiƒX‚̃Tƒvƒ‰ƒCƒY‚ɑ΂µ‚ĉº—Ž‚·‚éƒAƒmƒ}ƒŠ�[Œ»�Û‚Å‚ ‚é�B‚Ü‚½�Cƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ÉŠÖ‚·‚邱‚ê‚Ü‚Å‚ÌŒ¤‹†‚Å‚Í�C—˜‰v‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚¾‚¯‚Å‚Í‚È‚­�CƒLƒƒƒbƒVƒ…ƒtƒ��[‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg
�ipost?cash?flow?announcement?drift�j‚ɂ‚¢‚Ä‚àŒŸ�Ø‚ª�s‚í‚ê‚Ä‚¨‚è�C‚»‚ê‚ç‚Ì‘¶�Ý‚ªŠm”F‚³‚ê‚Ä‚¢‚邪�C‚±‚Ì‚±‚Æ‚Í—˜‰v�î•ñ‚âƒLƒƒƒbƒVƒ…ƒtƒ��[�î•ñ‚ÌŒˆŽZ”­•\Œã‚É‚¨‚¯‚銔‰¿‚Æ‚ÌŠÖ˜A�«‚ð�Ø‹’•t‚¯‚Ä‚¢‚é�B‚µ‚©‚µ‚È‚ª‚ç�C—˜‰v�î•ñ‚àƒLƒƒƒbƒVƒ…ƒtƒ��[�î•ñ‚àˆê”Ê‚ÉŒö•\‚³‚ê‚Ä‚¨‚è�C’N‚Å‚àƒRƒXƒg‚ð‚©‚¯‚邱‚Æ‚È‚­—˜—p‰Â”\‚Å‚ ‚é‚É‚à‚©‚©‚í‚炸�Cƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ª�¶‚¶‚é‚Ì‚Í‚È‚º‚©‚Æ‚¢‚¤‹^–â“_‚͈ˑR‚Æ‚µ‚Ä‘¶�Ý‚µ‚Ä‚¢‚é�Bƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚Ì‘¶�Ý‚ª‰½“x‚àŠm”F‚³‚ê‚éˆê•û‚Å�C‚»‚ÌŒ»�Û‚ª”­�¶‚·‚錴ˆö‚ɂ‚¢‚Ä‚Í�C‚¢‚Ü‚¾Š®‘S‚É‚Í“Ë‚«Ž~‚ß‚ç‚ê‚Ä‚¢‚È‚¢‚Ì‚Å‚ ‚é�B‚±‚̂悤‚È�󋵂ɂ¨‚¢‚Ä�CƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“�öŠo‰¼�à‚Í�C—˜‰v‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ª�¶‚¶‚錴ˆö‚ðƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“‚Å�à–¾‚·‚邱‚Æ‚ðŽŽ‚Ý‚é‚à‚Ì‚Å‚ ‚é�B‚»‚̉¼�à‚ÌŽåŽ|‚Í�CƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“‰º‚Å‚Í�C“ŠŽ‘‰Æ‚ÍŠé‹Æ‚Ì�«—ˆ‹Æ�тɃCƒŠƒ…�[ƒWƒ‡ƒ“�i�öŠo�j‚ð‚¢‚¾‚¢‚Ä‚¨‚è�C‚»‚Ì‚±‚Æ‚ª“ŠŽ‘‰Æ‚Ì�‡—��«‚ð’ቺ‚³‚¹‚Ä�Cƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ð�¶‚¶‚³‚¹‚é‚Æ‚¢‚¤‚±‚Æ‚Å‚ ‚é�B–{�e‚Ì�\�¬‚͈ȉº‚Ì‚Æ‚¨‚è‚Å‚ ‚é�B‚Ü‚¸�CŽŸ�ß‚Å‚Í�CƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒgŒ¤‹†‚É‚¨‚¯‚éƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“�öŠo‰¼�à‚̈ʒu‚¯‚ɂ‚¢‚Ä�à–¾‚·‚é�B‘æ‚R�ß‚Å‚Í�CƒCƒ“ƒtƒŒ�[ƒVƒ‡ƒ“�öŠo‰¼�à‚ðŒŸ�Ø‚µ‚½Chordia and Shivakumar�i‚Q‚O‚O‚T�j‚ðŠTŠÏ‚µ‚Ä�C‚»‚Ì•ª�ÍŽè–@‚ÆŽå‚È•ª�ÍŒ‹‰Ê‚ðŠm”F‚µ�C‘æ‚S�ß‚Å‚Í�C“ú–{‚ÅŒŸ�Ø‚ð�s‚¤�Û‚É”FŽ¯‚µ‚Ä‚¨‚­‚ׂ«“_‚ðŽw“E‚µ‚Ä�C�ÅŒã‚É‚Þ‚·‚Ñ‚Æ‚µ‚½‚¢�B
en-copyright=
kn-copyright=

en-aut-name=NakagawaToyotaka
en-aut-sei=Nakagawa
en-aut-mei=Toyotaka
kn-aut-name=’†�ì–L—²
kn-aut-sei=’†�ì
kn-aut-mei=–L—²
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw
END

start-ver=1.4
cd-journal=joma
no-vol=38
cd-vols=
no-issue=1
article-no=
start-page=21
end-page=32
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2006
dt-pub=200606
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Post?Announcement Drift and Cash Flows
kn-title=ƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ƃLƒƒƒbƒVƒ…ƒtƒ��[
en-subtitle=
kn-subtitle=
en-abstract=The purpose of this paper is to discuss the relationship between post?announcement drift and the usefulness
of cash flow information. The post?announcement drift is the phenomenon that stock prices continue changing
for a direction even after the announcement days. The first evidence of the post?announcement drift was
indicated by the Ball and Brown (1968), and then many papers have been illustrated the robustness of the
evidences for the post?announcement drift phenomenon and tried to explain why the phenomenon occur. On the
other hand, the listed companies disclose the statement of cash flows, but the many papers focused on only the
post �gearnings�h announcement drift. So, this paper addresses not only earnings but also �gcash flows�h and
�gaccruals�h.
As for the causes of the post?earnings?announcement drift, we could classify roughly into two explanations.
First, the error of abnormal returns estimations causes the post?earnings?announcement drift. In other words,
the explanation asserts that the capital asset pricing model (CAPM) is not adequate to calculate the capital cost
enough to reflect the risk of stocks. That is to say, the explanation addresses the methodological issues. Bernard
and Thomas (1989) said it �gexplanation based on incomplete risk adjustment�h. The other is said �gexplanation
based on delayed response to information�h by them. In the case, we could interpret the phenomenon as the
insufficiency of the investors�f understanding for the accounting information and other the limitations in the real�@transactions.
Many papers, for example Rayburn (1986), Wilson (1986) (1987), Ali (1994), Pfeiffer et al. (1998), Barth et
al. (1999) (2001), documented the usefulness of cash flows information, and many papers investigated the post?
earnings?announcement drift, but did not for cash flows one. So, this paper addressed the post?cash?flows?
announcement drift and post?accruals?announcement drift, especially the relationship between them and�@usefulness of cash flows information.
This paper has two conclusions, which are (1) the usefulness of cash flows information might influence the
interpretation of post?earnings?announcement drift, (2) it is necessary that we will investigate the post?cash?
flows?announcement drift.
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‚»‚̂悤‚ÈŠ”‰¿“®Œü‚Í�CƒvƒŒƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg�ipre?announcement drift�j‚ƌĂ΂ê�C‚»‚ê‚ç‚Ì“ñ‚Â‚ð‚ ‚í‚¹‚ăAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg�iannouncement drift�j‚ƌĂ΂ê‚Ä‚¢‚é�Bƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒgŒ»�Û‚Í�CBall and Brown�i‚P‚X‚U‚W�j‚ª‚±‚ÌŒ»�Û‚ð— •t‚¯‚é�Ø‹’‚ðŽ¦‚µ‚Ĉȗˆ�CŽÀ�Ø“I‚ȉïŒvŠw‚̗̈æ‚ÅŠÖ�S‚ð�W‚ß‚Ä‚«‚½�B
–{�e‚Å‚Í�à–±�î•ñ‚Ì—L—p�«‚ÌŽ‹“_‚©‚ç�C‚±‚ÌŒ»�ۂƃLƒƒƒbƒVƒ…ƒtƒ��[�î•ñ‚Ì—L—p�«‚Æ‚ÌŠÖŒW‚ð’T‚Á‚Ä‚Ý‚½‚¢�B•~Ÿ¥‚·‚ê‚Î�C–{�e‚Ì–Ú“I‚Í�C—˜‰v‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg�ipost?earnings?announcement drift�j‚ÉŠÖ‚·‚邱‚ê‚Ü‚Å‚ÌŒ¤‹†‚ð’­‚ß‚½�ã‚Å�CƒLƒƒƒbƒVƒ…ƒtƒ��[‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg�ipost?cash?flows?announcement drift�j‚ðˆµ‚Á‚Ä‚¢‚éShivakumar�i‚Q‚O‚O‚U�j‚ÌŒŸ�Ø“à—e‚ɂ‚¢‚Ä�lŽ@‚µ‚È‚ª‚ç�Cƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒgŒ»�ۂƃLƒƒƒbƒVƒ…ƒtƒ��[�î•ñ‚Ì—L—p�«‚Æ‚ÌŠÖŒW‚ɂ‚¢‚ÄŒŸ“¢‚·‚邱‚Æ‚Å‚ ‚é�Bƒ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ɂ‚¢‚Ä‚Í�C•Ä�‘‚ð’†�S‚É‚±‚ê‚Ü‚Å‚É‘½‚­‚ÌŒ¤‹†‚ª“WŠJ‚³‚ê‚Ä‚«‚½�B‚µ‚©‚µ‚È‚ª‚ç�C‚»‚ê‚ç‚Ì�æ�sŒ¤‹†‚Í—˜‰v‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ÉŠÖ‚·‚é‚à‚Ì‚ª‚Ù‚Æ‚ñ‚Ç‚Å‚ ‚é�B‚±‚ê‚ɑ΂µ‚Ä�C–{�e‚ł̓LƒƒƒbƒVƒ…ƒtƒ��[‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ɂ‚¢‚Ä‚à–Ú‚ðŒü‚¯‚Ä‚¢‚é�B‚Ü‚½�CƒLƒƒƒbƒVƒ…ƒtƒ��[�î•ñ‚Ì—L—p�«‚ÉŠÖ‚·‚錤‹†‚Í�C‚±‚ê‚Ü‚ÅŠú‘ÒŠOƒLƒƒƒbƒVƒ…ƒtƒ��[•Ï�”‚ƃŠƒ^�[ƒ“‚Æ‚ÌŠÖ˜A�«�i�î•ñ“à—e�j‚âƒLƒƒƒbƒVƒ…ƒtƒ��[ƒ‚ƒfƒ‹‚ÌŠ”‰¿�à–¾—Í�iŽ�•ª‰¿’l•]‰¿�j‚Æ‚¢‚¤Ž‹“_‚©‚ç�s‚í‚ê‚邱‚Æ‚ª‘½‚©‚Á‚½‚ª�C–{�e‚Å‚Í�CƒLƒƒƒbƒVƒ…ƒtƒ��[�î•ñ‚Ì—L—p�«‚ƃ|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚Æ‚ÌŠÖŒW‚ɂ‚¢‚ÄŒŸ“¢‚µ‚Ä‚¢‚é�B‚±‚ê‚炪–{�e‚̈Ӌ`‚Å‚ ‚é�B–{�e‚Ì�\�¬‚͈ȉº‚Ì‚Æ‚¨‚è‚Å‚ ‚é�B‚Ü‚¸ŽŸ�ß‚Å‚Í�C—˜‰v‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ÉŠÖ‚·‚邱‚ê‚Ü‚Å‚ÌŒ¤‹†‚ɂ‚¢‚Ä�C‚»‚ÌŒ»�Û‚Ì�à–¾•û–@‚ðŒð‚¦‚È‚ª‚ç�à–¾‚·‚é�BŽŸ‚É�C‘æ‚R�ß‚Å‚Í�CƒLƒƒƒbƒVƒ…ƒtƒ��[‚̃|ƒXƒgƒAƒiƒEƒ“ƒXƒ�ƒ“ƒgƒhƒŠƒtƒg‚ðŒŸ�Ø‚·‚éˆÓ‹`‚ɂ‚¢‚Ä�C‚»‚Ì‘O’ñ‚Æ‚È‚é�l‚¦•û‚âƒLƒƒƒbƒVƒ…ƒtƒ��[�î•ñ‚Ì—L—p�«‚Æ‚ÌŒ‹‚т‚«‚ÆŠÖŒW‚¯‚Ä�lŽ@‚·‚é�B�ÅŒã‚É�C–{�e‚ÌŒŸ“¢Ž–�€‚ð�®—�‚µ�C�¡Œã‚ÌŒŸ“¢‰Û‘è‚ɂ‚¢‚Ä�lŽ@‚·‚邱‚Æ‚ÅŒ‹‚Ñ‚Æ‚µ‚½‚¢�B
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en-aut-name=NakagawaToyotaka
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aut-affil-num=1
ORCID=

affil-num=1
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END

start-ver=1.4
cd-journal=joma
no-vol=1
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no-issue=
article-no=
start-page=91
end-page=97
dt-received=
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dt-accepted=
dt-pub-year=1991
dt-pub=19910325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The Neurophysiological Implications of an Atypical Slow Negative Potential in Short Interval CNV�@Paradigm
kn-title=CNV‚Ì‹L˜^�ðŒ�‚Æ”ñ’èŒ^”gŒ`‚Ì�¶—�Šw“IˆÓ‹`
en-subtitle=
kn-subtitle=
en-abstract=CNV‚Ì‹L˜^�ðŒ�‚ðŒŸ“¢‚·‚é–Ú“I‚Å�AŒ’�NŽá”N�¬�l49–¼�i’j12�A�—37�j‚ð‘Î�Û‚ÉS(1)-S(2)+Rƒpƒ‰ƒ_ƒCƒ€‚ð—p‚¢‚ÄCNV‚ð‹L˜^‚µ‚½�BS(1)-S(2)ŠÔŠu2•b‚Ì‚Ù‚¤‚ª3•b‚æ‚è‚àˆÀ’肵‚ÄCNV‚ª‹L˜^‚³‚ꂽ‚ª�AŽhŒƒŠÔŠu‚Æ‚Í–³ŠÖŒW‚É26�`30�“‚ÌŽŽ�s‚Å“ñ•ô�«‚̉A�«•Ï“®‚ð‚à‚”ñ’èŒ^‚ÈŠÉ“dˆÊ‚ª‹L˜^‚³‚ꂽ�B‚±‚ÌŠÉ“dˆÊ‚Í“¯ˆê”팟ŽÒ‚Å‚à�oŒ»�«‚ªˆêŠÑ‚¹‚¸�AŒÂ‘Ì�·‚æ‚è‚à”팟ŽÒ‚Ì�ó‘ԂɈˑ¶‚µ‚Ä‚¢‚½�B“ñ•ô�«‰A�«”g‚Ì‚¤‚¿�AŒãŠú�¬•ª‚Í�€”õ“dˆÊ‚ɑΉž‚·‚é‚à‚Ì‚ÆŽv‚í‚ꂽ‚ª�A‘OŠú�¬•ª‚ÍS(1)Œã900�`1100msec‚Ƀs�[ƒN‚ð‚à‚‰A�«”g‚Å�A‚±‚ê‚Ü‚Å•ñ��‚³‚ꂽCNV‚Ì—v‘f”g‚Ƃ͑Ήž‚µ‚È‚©‚Á‚½�B‚Ü‚½�A‚±‚Ì”ñ’èŒ^CNV‚ðŽ¦‚·”팟ŽÒ‚Å‚ÍCNV�oŒ»‚ª•sˆÀ’è‚Å�ASVR‚¨‚æ‚уpƒ^�[ƒ“VEP‚Ì�U•�‚ª’á‚¢ŒXŒü‚ª‚ ‚è�AŽŽ�sŽž‚̔팟ŽÒ‚ÌŠo�Á�…�€’ቺ‚æ‚é‚à‚Ì‚Å‚Í‚È‚¢‚©‚Æ�l‚¦‚ç‚ꂽ�B
kn-abstract=We recorded a slow negative potential from Cz (10/20 method) in 49 healthy students (12 male, 37 female, mean age 19.1) by a short interstumulus interval CNV paradigm. The interstimulus interval was 2 or 3 seconds, the warning stimulus presented at random or regular interval at 0.2 Hz. An atypical negative variation with two separated negative peaks was recorded in 26.0-30.6% trials regardless of interstimulus interval or modality of warning stimulus presentation, while a typical CNV was recorded in 32.0-59.2% of trials. No apparent negative variation was recorded in 14.3-18.4% in 2 seconds interstimulus interval, and 28-38% in 3 seconds interstimulus interval, showing that 2 seconds interval is better to get stable CNV recording than 3 seconds interval. The first negative wave of the atypical negative variation was 692-799msec in duration, but frequently prolonged to 1000msec or more in 3 seconds interval. It usually had negative peak around 900-1100msec, but sometimes around 1500msec. This features are different from any reported negative components of CNV. The second negative wave began 800-1200msec before second stimulus, and had its peak just before second stimulus, showing common features with readiness potential. The appearance of CNV was unsatble in the students in which the atypical negative variation was recorded in regular, 2 seconds intersitimulus interval, and the amplitude of slow vertex response and pattern reversal visual evoked potential was lower in thses students than in the students in which a typical CNV was recorded more than 3 times in total 4 times of trials. These findings indicate that the atypical variation observed in this study is due to a lowered arousal level or cortical neuronal activity, rather than a separated appearance of different components of CNV.
en-copyright=
kn-copyright=

en-aut-name=OkamotoMotoi
en-aut-sei=Okamoto
en-aut-mei=Motoi
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kn-aut-mei=Šî
aut-affil-num=1
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en-aut-name=TeminoMasato
en-aut-sei=Temino
en-aut-mei=Masato
kn-aut-name=Žè–ª�³�l
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kn-aut-mei=�³�l
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ORCID=

en-aut-name=NakagawaNaohisa
en-aut-sei=Nakagawa
en-aut-mei=Naohisa
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en-aut-name=MoriHirokazu
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ORCID=

affil-num=1
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kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”‰q�¶‹Z�pŠw‰È

affil-num=2
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kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”‰q�¶‹Z�pŠw‰È

affil-num=3
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kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”‰q�¶‹Z�pŠw‰È

affil-num=4
en-affil=
kn-affil=‰ªŽR‘åŠwˆã—ËZ�p’ZŠú‘åŠw•”‰q�¶‹Z�pŠw‰È
en-keyword=contingent negative variation
kn-keyword=contingent negative variation
en-keyword=atypical slow negative potential
kn-keyword=atypical slow negative potential
en-keyword=arousal level
kn-keyword=arousal level
en-keyword=slow vertex response
kn-keyword=slow vertex response
en-keyword=visual evoked potential
kn-keyword=visual evoked potential
END

start-ver=1.4
cd-journal=joma
no-vol=87
cd-vols=
no-issue=1
article-no=
start-page=85
end-page=90
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1998
dt-pub=199802
dt-online=
en-article=
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en-subject=
kn-subject=
en-title=Photodecomposition of Ergosterol by Near-UV irradiation in the Plasma Membrane of the Yeast Rhodotorula minuta
kn-title=’·”g’·Ž‡ŠOŒõ�ÆŽË‚É‚æ‚é�y•ê Rhodotorula minuta �×–E–ŒƒGƒ‹ƒSƒXƒeƒ��[ƒ‹‚Ì•ª‰ð
en-subtitle=
kn-subtitle=
en-abstract=�y•êRhodotorula minuta‚É‚¨‚¯‚éƒJƒ�ƒeƒmƒCƒh‚ÌŒõ—U“±�‡�¬‚¨‚æ‚Ñ�×–E–Œ‚Ì‹@”\‘¹��‚ÉŠÖ‚í‚é�‰ŠúŒõ‰»Šw”½‰ž‚ɂ‚¢‚Ä‚Ì’mŒ©‚𓾂é–Ú“I‚Å�A’·”g’·Ž‡ŠOŒõ(UV-AŒõ)‚É‚æ‚é�×–E–ŒƒGƒ‹ƒSƒXƒeƒ��[ƒ‹‚Ì•ª‰ð‚𒲂×�AŽŸ‚ÌŒ‹‰Ê‚𓾂½�B�y•ê‹Û‘Ì‚¨‚æ‚Ñ‹Û‘Ì‚©‚ç’²�»‚µ‚½�×–E–Œ’²�»•i‚É’·”g’·Ž‡ŠOŒõ‚ð�ÆŽË‚·‚é‚Æ‹zŽûƒXƒyƒNƒgƒ‹‚É”÷�ׂȕω»‚ª�¶‚¶‚邱‚Æ‚ð”F‚ß‚½�B�×–E–Œ’²�»•i‚É�¶‚¶‚½‹zŽûƒXƒyƒNƒgƒ‹‚̕ω»‚Í�×–E–ŒƒGƒ‹ƒSƒXƒeƒ��[ƒ‹‚ªŒõ‰»Šw•ª‰ð‚ðŽó‚¯‚邱‚Æ‚ð—\‘z‚³‚¹�A‚±‚Ì—\‘z‚ÍHPLC•ª�Í‚É‚æ‚Á‚ÄŠm‚©‚ß‚ç‚ꂽ�B‚Ü‚½�Aƒ‚ƒfƒ‹Œn‚Å‚ÌŽÀŒ±‚É‚æ‚Á‚Ä�A�×–E–Œ’†‚̃Gƒ‹ƒSƒXƒeƒ��[ƒ‹‚ÌŒõ‰»Šw”½‰ž‚É‚Í“Á•Ê‚ÈŒõŽó—e‘Ì‚ ‚é‚¢‚ÍŒõ‘�Š´�܂͉î�Ý‚µ‚Ä‚¨‚炸�AƒGƒ‹ƒSƒXƒeƒ��[ƒ‹Ž©�g‚ªŒõŽó—e‘Ì‚Å‚ ‚蔽‰žŠîŽ¿‚Æ‚È‚Á‚Ä‚¢‚邱‚Æ‚ª–¾‚ç‚©‚É‚È‚Á‚½�B
kn-abstract=In search for primary photochemical reaction related to photoinduced carotenogenesis and photoinactivivation in yeast Rhodotorula minuta, the influence of near-UV radiation (300-400 nm) on ergosterol in the plasma membrane of the yeast. Irradiation by near-UV of intact cells and the plasma membrane preparation from the yeast caused changes in their absorption spectra. For the plasma membrane, difference spectra measured after irradiation of near-UV suggested the decomposition of ergosterol and the suggestion was proved by HPLC analysis. Experiments in model systems revealed that ergosterol itself was the photoreceptor in the photochemical reaction, and that there was not any other photoreceptor or photosensitizer which was related to photochemical reaction of ergosterol decomposition in the plasma membrane.
en-copyright=
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en-aut-name=NakaumaMakoto
en-aut-sei=Nakauma
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en-aut-name=AramiShin-ichiro
en-aut-sei=Arami
en-aut-mei=Shin-ichiro
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kn-aut-sei=�rŒ©
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en-aut-name=HadaMegumi
en-aut-sei=Hada
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en-aut-name=NakagawaIchiro
en-aut-sei=Nakagawa
en-aut-mei=Ichiro
kn-aut-name=’†�ìˆê˜Y
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aut-affil-num=4
ORCID=

en-aut-name=MurataYoshiyuki
en-aut-sei=Murata
en-aut-mei=Yoshiyuki
kn-aut-name=‘º“c–F�s
kn-aut-sei=‘º“c
kn-aut-mei=–F�s
aut-affil-num=5
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en-aut-name=TadaMikiro
en-aut-sei=Tada
en-aut-mei=Mikiro
kn-aut-name=‘½“cŠ²˜Y
kn-aut-sei=‘½“c
kn-aut-mei=Š²˜Y
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ORCID=

affil-num=1
en-affil=
kn-affil=‰ªŽR‘åŠw

affil-num=2
en-affil=
kn-affil=”_—Ñ�…ŽY�È�H•i‘��‡Œ¤‹†�Š

affil-num=3
en-affil=
kn-affil=�_ŒË‘åŠw—�Šw•”

affil-num=4
en-affil=
kn-affil=‹ã�B”_�­‹Ç

affil-num=5
en-affil=
kn-affil=‰ªŽR‘åŠw

affil-num=6
en-affil=
kn-affil=‰ªŽR‘åŠw
en-keyword=Rhodotorula minuta
kn-keyword=Rhodotorula minuta
en-keyword=near-UV
kn-keyword=near-UV
en-keyword=ergosterol
kn-keyword=ergosterol
en-keyword=absorbance change
kn-keyword=absorbance change
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