| ID | 14009 |
| Eprint ID | 14009
|
| フルテキストURL | |
| タイトル（別表記） | Studies on the treatment of intractable asthman Part 1. Effect of Saiboku-to on cell-mediated allergy in the experimental asthma using guinea pigs
|
| 著者 |
岡本 章一
岡山大学医学部第二内科学教室
|
| 抄録 | Saiboku-to seems to be a useful drug in the teatment of intractable asthmatics. The pharmacological effect of Saiboku-to was examined in an experimental model of bronchial asthma with cell-mediated allergy in guinea pigs. The fundings revealed that Saiboku-to inhibited the late asthmatic response. It suppressed the lymphocyte blastogensis by ascaris antigen and eosinophil infiltration into BALF and peribronchial tissue. Moreover, Saiboku-to lowered the levls of LTB4 and LTC4 in the cardiac blood, but not the antigen-specific IgG subclass. These findings suggest that the inhibitory effect of Saiboku-to on the late asthmatic response is caused by the suppression of cell-mediated allergy.
|
| キーワード | Saiboku-to
cell-mediated allergy
actively sensitized model
lymphocyte
leukotrienes
|
| 備考 | 原著
|
| 発行日 | 1994
|
| 出版物タイトル |
岡山医学会雑誌
|
| 出版物タイトル（別表記） | Journal of Okayama Medical Association
|
| 巻 | 106巻
|
| 号 | 3-4号
|
| 出版者 | 岡山医学会
|
| 出版者（別表記） | Okayama Medical Association
|
| 開始ページ | 305
|
| 終了ページ | 314
|
| ISSN | 0030-1558
|
| NCID | AN00032489
|
| 資料タイプ |
学術雑誌論文
|
| オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/106/3-4/106_3-4_305/_article/-char/ja/
|
| 関連URL | http://www.okayama-u.ac.jp/user/oma/index.html
|
| 言語 |
日本語
|
| 著作権者 | 岡山医学会
|
| 論文のバージョン | publisher
|
| 査読 |
有り
|
| Eprints Journal Name | joma
|
