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JaLCDOI 10.18926/40348
タイトル(別表記) MEDICAL STUDIES ON CHONDROITIN SULFATE (III)
フルテキストURL 013_036_041.pdf
著者 大島 良雄| 外園 正純|
抄録 2-5cc. of 1% Rodium chondroitin-sulfate solution subcutaneouRly or 2cc. of 5% solution intraveneously was administered to 37 cares of painful disorders such as headache, backache or arthralgia. A marked improvement was obtained in 12 cares and a moderate result was seen in 16 cases. No definite change was proved concerning blood pressure in the patients and detoxicating effect in animal experiment.
出版物タイトル 岡山大学温泉研究所報告
発行日 1953-12
13巻
開始ページ 36
終了ページ 41
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40340
言語 日本語
論文のバージョン publisher
NAID 40017532453
JaLCDOI 10.18926/40347
タイトル(別表記) KLINISCHE UND EXPERIMENTELLE UNTERSUCHUNGEN ÜBER DIE WIRKUNG VON THERMALBÄDERN AUF DIE SEXUALFUNKTION VON FRAUEN (5) UNTERSUCHUNGEN ÜBER DIE BEEINFLUSSUNG DER QUAINTITÄT DER ACETYLCHOLINARTIGEN SUBSTANZ IN ZWISCHENHIRN DER RATTE NACH THERMALBADE
フルテキストURL pitsr_013_031_035.pdf
著者 田中 良憲|
抄録 In frühen Arbeiten habe ich den Nachweiss erbracht, dass Thermalbädern den Brunstzyklus der weiblichen Ratten regelmässig werden lassen, und diese Erscheinung auf die Steigerung der Hupophysenvorderlappenfunktion zurückzuführen ist. Andererseits ist es bekannt, dass Zunahme der acetylcholinartigen Substanz der Zwischenhirn die Steigerung der Hypophysenvorderlappenfunktion mit sich bringt. Unter diesen Gesichtspunkten wurden die Bestimmnngen der acetylcholinartigen Substanz in zwischenhirn der Ratte nach Thermalbade vorgennommen. 47 männliche Ratte wurden in Misasa Therma - radioaktive Thermen - 10 Minuten lang bei 42°C gebadet, dann in 4 Gruppen geteilt, und εfort, an 30., 60., und 90. Minute nach dem Bade wurde diese Subfotanz nach Methode von M. rectus abdeminis der Frosch bestimmt, und mit kontrolltiere verglichen. Es wurde festgestellt, dass freie acetylcholinartige Snbstanz sich an 30. Minute nach dem Bade vermehrte, aber an anderen Zeiten kein statistisch signifikanter Unterschied zwischen Badgruppe lmd Kontrollgruppre hinisichtlich des Gehalt der freien, kombinierten und gesamten acetylcholinartigen Subtanz war. Die Tatsachen lassen daran denken, dass Zunahme der freien acetylcholinartigen Substanz in Zwischenhirn, die gescbah nach dem Thermalbade, sich an Verbesserung der Sexualfunktion von Thermalbädern vielleicht beteiligt. Üher diese Erscheinungen werden die Rolle der Radiumemanation im Thermalwasser und Unterschied zwischen Thermalwasser und Süsswasser in künftigen Arbeiten untersucht werden.
出版物タイトル 岡山大学温泉研究所報告
発行日 1953-12
13巻
開始ページ 31
終了ページ 35
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40340
言語 日本語
論文のバージョン publisher
NAID 120002484881
JaLCDOI 10.18926/40346
タイトル(別表記) STUDIES ON SERUM MUCOPROTEIN (2) RELATION BETWEEN SERUM MUCOPROTEIN LEVEL AND DIFFERENTIAL AGGLUTINATION TEST FOR RHEUMATOID ARTHRITIS. AN EXPERIMENTAL AND CLINICAL STUDY
フルテキストURL 013_024_030.pdf
著者 上田 良雄|
抄録 (1) Mucoprotein level in serum and agglutination reaction by Rose for rheumatoid arthritis were measured in 40 cases of rheumatoid arthritis, cancer, pulmonary tuberculosis or liver disease (mostly acute hepatitis). A raised titer of mucoprotein was often observed in cancer, and a marked rise in agglutination titer was often proved in rheumatoid arthritis. But no significant correlation was proved between the serum mucoprotein level and agglutination test in patients. (2) [n animal experiment an inereased agglutination titer was caused by sensitization with egg albumin, Arthus' s phenomenon, anaphylactic, shock, thermal spring bath, X-ray irradiation, blocking of reticuloendothelial system, liver injuries, injection of A. C. T. H., adrenaline, atropin or pilocarpin. A simultaneoas rise in serum mucoprotein level was observed after sensitization, thermal bath, X-ray irradiation, administmtion of chloroform, injection of toxic agents to vegetative nerve system. And a significant positive linear correlation was proved between the serum mucoprotein level and agglutination titer in the animal experiment on the whole. But a dissociation in this relation was observed during anaphylactic shok. Namely serum mucoprotein level tended to fall soon after the reinjection, while the agglutination titer rose higher temporarily and then both showed a tendency to decrease.
出版物タイトル 岡山大学温泉研究所報告
発行日 1953-12
13巻
開始ページ 24
終了ページ 30
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40340
言語 日本語
論文のバージョン publisher
NAID 40017532450
JaLCDOI 10.18926/40345
タイトル(別表記) BALNEOLOGICAL STUDIES USING RADIOACTIVE ISOTOPES (3)
フルテキストURL pitsr_013_018_023.pdf
著者 横田 剛男| 芦沢 峻|
抄録 By using labelled sodium sulfate or calcium sulfate (sulfate containing S(35)) the transition of sulfate ion into the body across the skin was investigated soon after taking a bath in sodium sulfate or calcium sulfate solution under varing conditions. Mice were used for experiments. The percutaneous absorption of sulfate ion proved to decrease gradually in the course of serial baths in sodium sulfate solntion and was accelerated by making a fresh burn on the skin of the bathed animals, but it showed a tendency to decrease as the wound became more and more healed. The application of basic dye to the skin (e.g. 1% methylenblue or 1% fuchsin solution) increased the transition of sulfate ion into the test animal. Little difference was proved between the bath in sodium sulfate and calcium sulfate solution with respect to the penetration of sulfate ion. Passage of sulfate ion from the bath water through the skin was a little promoted by the use of sodium sulfate solution than by the use of calcium sulfate solution.
出版物タイトル 岡山大学温泉研究所報告
発行日 1953-12
13巻
開始ページ 18
終了ページ 23
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40340
言語 日本語
論文のバージョン publisher
NAID 120002484880
JaLCDOI 10.18926/40344
タイトル(別表記) STUDIES ON VITRIOL SPRINGS (4) ON THE COPPER, ZINC, NICKEL, AND COBALT CONTENTS OF BLOOD AFTER THE INTERNAL USE OF A VITRIOL WATER
フルテキストURL 013_015_017.pdf
著者 大島 良雄| 芦沢 峻|
抄録 Sotozono proved that the administration of daily 20cc of Fujino Mineral Water (an acid vitriol water containing copper, zinc, nickel and cobalt) has a remarkably beneficial effect on several kinds of hypochromic anemia. It contains 9.56gms of iron, 0.007gm of zinc, 0.005gm of copper 0.001gm of nickel, and 0.006gm of cobalt in one liter. 20 - 40cc of Fujino water was diluted 5 - 10 fold with plain water and administered to the fasting patients perorally. Blood samples were taken from cubital vein before, 1, 2, 4, 6, 24, 48, and 72 hours after the intake of the vitriol water. Copper, zinc, nickel and cobalt contents of the blood samples were measured by Ashizawa' s dithizone- chromatographic method. It was shown that copper, nickel, and cobalt contents of blood rose unexpectedly high temporarily, in a manner that did not correspond to their amount in the given mineral water. So that the mobilization of copper, nickel, and cobalt in the body after the intake of the mineral IVrter was susrected. Zinc content of blood showed no constant tendency.
出版物タイトル 岡山大学温泉研究所報告
発行日 1953-12
13巻
開始ページ 15
終了ページ 17
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002484879
JaLCDOI 10.18926/40343
タイトル(別表記) STUDIES ON VITRIOL SPRINGS (3) EFFECT OF THE INTERNAL USE OF VITRIOL WATER OF FUJINO ON THE GASTRIC ACIDITY
フルテキストURL pitsr_013_009_014.pdf
著者 森永 寛|
抄録 Fujino Spring is the foremost acid vitriol spring of Japan in ferrous and ferric ion contents. Six years ago the author reported that its internal use had an remarkable hemopoietic effect on hypochromic anemia and delayed the curve of alimentary hyperglycemia in rabbit. Twenty ml. of this vitriol water was diluted with plain water to two hundred ml. and was given to twenty one patients by stomach tube at 37°C. Gastric acidity of the patients was measured at 30 minutes intervals during the following 150 minutes after the administration of the water. In six cases of normal acidity no significant difference was proved between the effects of the mineral water and of caffein control (0.2g. in 200 ml.). In six cases of hyperacidity it seemed that the vitriol water decreased in the acidity curve compared with control. In nine patients of hypo- and anacidity both free and total acidity curve was elevated by the use of the mineral water compared with caffein control. The internal use of Fujino Spring in moderate dilution with plain water regulated the gastric acidity.
出版物タイトル 岡山大学温泉研究所報告
発行日 1953-12
13巻
開始ページ 9
終了ページ 14
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002484879
JaLCDOI 10.18926/40342
タイトル(別表記) ON THE EXISTENCE OF RADIUM B, RADIUM C AND THORIUM B IN MISASA HOT SPRINGS
フルテキストURL pitsr_013_005_008.pdf
著者 佐藤 三雄|
抄録 The author tried to measure RaB, RaC and ThB in the hot spring waters using G-M counter and proved the existence of RaB and ThB in Misasa Hot Springs. To 100 liters of spring water ahout 20 gms of ferric chloride and then sodium hydroxide were added. Precipitate was dissolved in hydrochloric acid and after adding bismuth and lead, the solution was saturated with hydrogen sulfide. The precipitate of sulfides was filtered and ignited to ashes after drying. The β-activity of the ashes was measured by a mica-window type G-M counter with the recording circuits of scale of 16. Natural background was 50±5 connts per minutes. Six spring waters of Misasa, namely "Spring of Branch Laboratory", "Nakayu", "Gunze" "O-T-R", "Jwayu", and "Tsukiminoyu" were investigated. RaB was detected in all samples. ThB was found only in "Gunze" and "O-T-R". ThB content of "Gunze" was estimated, to be roughly 1×10(-12) Curie units per liter.
出版物タイトル 岡山大学温泉研究所報告
発行日 1953-12
13巻
開始ページ 5
終了ページ 8
ISSN 0369-7142
言語 英語
論文のバージョン publisher
NAID 120002484878
JaLCDOI 10.18926/40341
フルテキストURL pitsr_013_001_005.pdf
著者 Umemoto, Shunji|
抄録 Various colormetric methods for determining magnesium in natural waters have been studied, and the methods using 8-oxyquinolin, ammonium molybdate and titan yellow were studied most frequently(1)), following the studies on the interfering ions(2)). Brilliant yellow(3)), l-amino-2-naphthol-6-sulfonic acid(4)) and other new reagents were also used. E. D. T. A. was used, but the determination by using this reagent is not exact. Present reagent already reported by T. Ashizawa(5)), magneson II, is insoluble in water, soluble in alkali and hardly soluble in ethanol. In the existence of magnesium ion, the color of solution varies from pink-violet (in alkali) and orange (in ethanol) to blue-violet. This variation of color was evaluated photometrically by Shimadzu photoelectric spectrophotometer, and moreover the grades of interference by interfering ions were clarified.
出版物タイトル 岡山大学温泉研究所報告
発行日 1953-12
13巻
開始ページ 1
終了ページ 5
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40340
言語 英語
論文のバージョン publisher
NAID 120002484877
JaLCDOI 10.18926/40332
タイトル(別表記) MEDICAL STUDIES ON THE RURAL PEOPLE (II) A STUDY ON THE INCIDENCE OF STRUMA IN THE SOUTH-WESTERN RURAL DISTRICTS OF OKAYAMA PREFECTURE, JAPAN
フルテキストURL pitsr_014_051_056.pdf
著者 森永 寛|
抄録 The author investigated the thyroid glands of 1480 school children (aged from 6 to 14) living in the vicinity of Yakage, the south-western rural district of Okayama Prefecture, and 1516 out-patients of Yakage Hospital, in 1950. The incidence of struma among the school children was 4.6 per cent and among the out-patients 4.7% on an average, and the percentage of struma in the spring (7.8%) was higher than in the summer (2.98%). This result suggests that thyroid glands are in some way susceptible to seasonal influences, and it is therefore necessary to consider the effect of season during investigation. The white blood pictures of seven patients showed no specific findings.
出版物タイトル 岡山大学温泉研究所報告
発行日 1954-03
14巻
開始ページ 51
終了ページ 56
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002462907
JaLCDOI 10.18926/40331
タイトル(別表記) MEDICAL STUDIES ON THE RURAL PEOPLE (I) CLINICAL AND STATISTICAL OBSERVATIONS ON HOOKWORM DISEASE IN RURAL DISTRICTS
フルテキストURL pitsr_014_045_050.pdf
著者 森永 寛|
抄録 The author studied statistically 160 cases of hookworm infection who had been admitted to Misasa Branch of Okayama University Hospital, Misasa Hot Springs in Tottori prefecture, during 1946~1949 and 162 cases of out-patients with anchylostomiasis in Yakage Hospital, Okayama Prefecture, during 1949~1950. The clinical findings were as follows: (1). Females showed a higher incidence than males and the incidence ratio of infected persons to total out-patients increased with age up to the 50~69 years group. (2). The most patients consulted our hospital for the first time in April~May and in August, and 62 per cent of cases came within 3 months scince they had noticed disorders in some way, but 22% remained at home without medical cure more than a year. (3). Chief subjective complaints were palpitation of heart (35.3%), lassitude of legs (31.2%), pains in the abdomen (22.9%), feeling of dizziness (21.6%) and so on. (4). Laboratory findings: The total number of erythrocytes was between 1.23 and 5.54 millions per cubic millimeter and a moderate anemia almost always developed in the hookworm disease (77.9% of all cases). The number of white cells was normal or slightly increased. Relative or absolute eosinophilia was recognized in 83.5% of all patients. Wassermann's test was positive in 20%, and Takata's reaction positive in 53% of the cases. The acidity of the gastric juice was lower than normal. Hypo- and anacidity were verified in 58%. Both albumen and urobilinogen test in urine were positive in 5.4% of 61 cases. Sugar in none. (5). Treatment: Thymol, tetrachlorethylene and oil of chenopodium were used alternately to remove the worms. The eggs in stool became negative after 3-4 times of the administration of anthelmintics in 76 per cent of 151 cases. As mentioned above, the patients infected with hookworm had various functional disorders of bodies, but they consulted the hospital only when the farmer's busy season began and their trouble became unbearable. And then the recovery of anemia took a month or two. Prof. Kitayama reported that the cold environment under 9°C. in the winter had perished the larva of hookworm in the soil. From these viewpoints, the author proposed that examination and cure of hookworms should be carried out in the winter, the slack season for farming, to prevent the fall of working ability due to anchylostomiasis during the busy farming seasons.
出版物タイトル 岡山大学温泉研究所報告
発行日 1954-03
14巻
開始ページ 45
終了ページ 50
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40330
言語 日本語
論文のバージョン publisher
NAID 120002462906
JaLCDOI 10.18926/40329
タイトル(別表記) DIE ERFAHRUNGEN VON GYNEKOLOGISCHEN BALNEOTHERAPIE (5) DER EINFLUSS VON ORALEN ANWENDUNG VON THERMALWASSER AUF DIE LEBERFUNKTION VON SCHWANGEREN FRAU
フルテキストURL 014_038_044.pdf
著者 長谷川 安正|
抄録 Nach oraler Anwendung vom kochsalzhaitigen schwach radioaktiven Thermalwasser von MISASA 500 ccm bei 20 schwangeren Frauen (meistens S. S. IIM. bis S. S. IVM.) wurden die folgneden Untersuchungen über Leberfunktionen angestellt und mit dem Resultat nach oralen Anwendung von Süsswasser verglichen. 1) Das Thermalwasser steigerte die Zusammensetzungsfähigkeit von Hippursäure d. h· Entgiftungsfähigkeit von Leber. 2) Nach Asorbin S Methode erwies sich keine Veränderung. 3) Die Aussheidungsfähigkeit von Bromsulfalein wurde schwach. 4) 4 stundige Harnmenge nach den oralen Anwendung war weniger bei dem Thermalwasser als bei Süsswasser, und NaCl Menge in beiden Harn war gleich. In Rücksicht auf oben genannten Untersuchungen, trotz des speziellen Einflusses auf die Leberfunktion, wegen antidiuretischer Wirkung darf orale Anwendung des Thermalwassers von MISASA bei schwangeren Frau nur mit einer gewissen Vorsicht gemacht werden.
出版物タイトル 岡山大学温泉研究所報告
発行日 1954-03
14巻
開始ページ 38
終了ページ 44
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 40017532463
JaLCDOI 10.18926/40328
タイトル(別表記) KLINISCHE UND EXPERIMENTELLE UNTERSUCHUENGN ÜBER DIE WIRKUNG VON THERMALBÄDERN AUF DIE SEXUALFUNKTION VON FRAUEN (6) KONSCHE SILBERREAKTION VON HYPOPHYSEN-HYPOPHYSEN VORDERLAPPEN, OVARIUM UND NEBENNIERE VON RATTE UND DAS THERMALBAD
フルテキストURL pitsr_014_033_037.pdf
著者 田中 良憲| 長谷川 安正|
抄録 Konsche Siberreaktion (Kon : Silberreaktion der Zellen - Gustav Fischer) ist eine histochemische methode für den Nachweis der Reduktionskraft der Zellen, die von Professor Kon erfunden wurde und im Zusammenhang mit Vitalität der Zellen besonders der endokrinen Organe steht. Also bedeutet die starke Offenbarung dieser Reaktion die gesteigerte Funktion der Gewebe. Um zu forschen ob die geschlechtsfunktion durch Thermalbad beeinflusst wurde, wurde diese Reaktion auf die Hypophysenvorderlappen, Ovarium und Nebenniere der Ratte nach Thermalbad (schwach radioaktive Therme und H2S Therme, 42°C, 5 Minuten lang) angewandt. Sofort nach einmaligem Bad handelte es sich kein Unterschied zwischen Badgruppe und Komtrollgruppe. Nach eimal täglich 50 tägigen Btidern verstaerkte sich die Reaktion von Hypophysenvorderlappen und Corpus luteum von Ovarium (besonders bei H(2)S Therme) aber in anderer Gewebe befand keine Veraenderung sich. Also ist es klar, dass Funktion von Hypophysenvorderlappen und Ovarium nach wiederholten Thermalbaedern sich steigert.
出版物タイトル 岡山大学温泉研究所報告
発行日 1954-03
14巻
開始ページ 33
終了ページ 37
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002462905
JaLCDOI 10.18926/40327
タイトル(別表記) THE EFFECT OF THERMAL BATHS UPON THE ETHER-EJACULATION IN ALBINO RATS
フルテキストURL pitsr_014_030_032.pdf
著者 岡田 俊郎|
抄録 The rate of ejaculation induced by ether narcosis in adult male albino rats increased after the serial thermal baths of Misasa (at 42°C for 5 minutes) during 3 weeks. No remarkable difference was shown concerning the above-mentioned actions between the weakly and the strongly radioactive spring.
出版物タイトル 岡山大学温泉研究所報告
発行日 1954-03
14巻
開始ページ 30
終了ページ 32
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002462904
JaLCDOI 10.18926/40326
タイトル(別表記) ASOZU (WEAK COMMON SALT SPRING), HAMAMURA (SULPHATED BITTER SPRING), KAlKE (CALCIUM CHLORIDE CONTAINING SALINE SPRING) AND FUJINO (ACID ALUM VITRIOL SPRING) SPRING WATERS AND THE ALIMENTARY HYPERGLYCEMIA
フルテキストURL pitsr_014_022_029.pdf
著者 森永 寛|
抄録 There are many experimental reports and clinical observations about the internal use of thermal waters on carbohydrate metabolism, and alkaline springs, alkaline common salt springs and sulphur springs are used for the balneological therapy of diabetic patients. The author reported that the internal use of the radon springs of Japan, such as Misasa, Ikeda and Masutomi thermal waters promoted the action of insuline and inhibited the experimental hyperglycemia in rabbits, and he suggested that these radioactive waters also would be able to utilize for the diabetic treatment. On the other hand, trace elements such as Cu, Zn and Mn have protective effects against disturbed carbohydrate metabolism of diabetic body. Some thermal waters contain these trace elements in various degrees, and Oshima & Ashizawa observed that after the drinking of Fujino mineral water the iron, copper, nickel and cobalt content in blood rose temporarily. In this report, the author investigated the influence of the drinking of Asozu (weak common salt spring), Hamamura (sulphated bitter spring), Kaike (calcium chloride containing saline spring) and Fujino (acid alum vitriol spring) Spring waters upon the alimentary hyperglycemia in rabbits. Thirty ml. of 10% glucose solution in thermal water (Fujino Water was diluted twice with plain water) or in plain water per kg. of bodyweight was administered to the rabbit by stomach tube and blood sugar level was determined before, 1/2, 1, 2, 3 and 4 hours after the administration. The results were as follows: 1. The drinking of Asozu Spring water inhibited the alimentary hyperglycemia compared with the plain water as a control. 2. Hamamura Spring had a tendency to decrease the blood sugar level. 3. Kaike Spring water had no inhibitory a.ction upon the alimentary hyperglycemia. 4. In spite of the existence of trace elements, Fujino mineral water had no significant effect. The author supposed that this was due to its high acidity.
出版物タイトル 岡山大学温泉研究所報告
発行日 1954-03
14巻
開始ページ 22
終了ページ 29
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002462903
JaLCDOI 10.18926/40325
タイトル(別表記) EFFECT OF WATER LEVEL OF RIVER ON MINERAL SPRING
フルテキストURL pitsr_014_015_021.pdf
著者 梅本 春次|
抄録 From June 1953 to January 1954, the water temperature and amount of flow of a spring called IITanaka-no-Yu", Misasa Hot Springs, Tottori Prefecture, were observed continuously. It issues 10 metres north of the riverside of the River Misasa and a stream runs 3 metres south of it. The water level of the River and the stream were also observed. The water level of the stream have close connection with the water volume of rice-field which surround that spring, because it is a watercourse of irrigation to rice-field. It was found that when the amount of flow increased, the water temperature rose, namely there was a positive correlation between them, and the correlation coefficient was 0.952 (highly significant). The analysis of variance showed that the amount of flow would be affected by the water level of the River but would not be severely affected by that of the stream. The correlation between the amount of flow and the water level of the River was also positive and the correlation coefficient was 0.731 (highly significant). As a result of the analysis of variance, the computation of confidence limit and the analysis of covariance, in summer the averages of the amount of flow and the water temperature would be higher than those in autumn and winter. This difference was seemed to be induced by the water level of the stream. The end of the observation, a dam had been constructed 20 metres down (west) the River and she rised, but the effect of it must be observed after this.
出版物タイトル 岡山大学温泉研究所報告
発行日 1954-03
14巻
開始ページ 15
終了ページ 21
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002462902
JaLCDOI 10.18926/40324
タイトル(別表記) RADON CONTENT OF HOT SPRINGS IN TOTTORI PREFECTURE, JAPAN
フルテキストURL 014_001_014.pdf
著者 大島 良雄| 山田 尚春| 御船 政明|
抄録 1. Radon content of 166 thermal waters in IWAI, TOTTORI YOSHIOKA, HAMAMURA, TOGO, SEKIGANE, MISASA, and KAlKE Hot Springs was measured by I. M. Fontactoscope in the years 1950-1951. Of which 66 samples showed a radon content over 30×10(-10) curie units per liter. Namely, 50 springs in Misasa, 6 in Sekigane, 9 in Hamamura, and one in Togo belonged to the radioactive spring in the definition by Ministry of Social Welfare. The highest Radon content (1150×10(10) curie units per liter) was recorded in Hisuino-Yu in Misasa, where five springs had a radon content over 360×10(-10) curie units per liter. 2. No marked difference was proved between the results obtained this time and the data in the former reports concerning the radon content of these thermal springs. 3. Radon content proved higher in the springs which issue from granite than in the springs of other districts. No definite relation was proved between the radon content and water temperature. The radon content was generally high in simple thermals or in weak sodium chloride springs, low in sulfated springs and in saline springs which had a comparatively high sulfate content.
出版物タイトル 岡山大学温泉研究所報告
発行日 1954-03
14巻
開始ページ 1
終了ページ 14
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 40017532457
JaLCDOI 10.18926/40322
タイトル(別表記) THE CLINICAL STUDIES OF RHEUMATOID ARTHRITIS (I)
フルテキストURL 016_035_048.pdf
著者 森永 寛|
抄録 The value of spa treatment of rheumatic disease is an established feature of medical management based on experiences for many centuries. The author has been practising the balneotherapy of rheumatic diseases at Misasa Spa for several years, and has found this therapy efficacious in many cases in relieving the anemia that accompanies rheumatoid arthritis. For this reason, the author is investigating the metabolism of iron in rheumatic anemia, which is expected to occur in the course of the spa treatment. In this report, the results of clinical examinations of 24 patients with rheumatoid arthritis, of the type (2. 2. 2.) Polyarthritis systemica chronica (in Prof. Kodama's classification of arthritis), are described. I. Some observations of anemia in rheumatoid arthritis 1. The peripheral blood The number of erythrocytes is 266×10(4)~455×10(4)/c. mm. (average: (381±32)×10(4)/c. mm.), Hb-content : 55~90% (average : 76±5.8%), and the color index is about 1.0. The anemia of rheumatic disease treated is mostly normochromic. The white blood count is between 3240 and 13300/c. mm. (average: 6421±955/c. mm. ), and the number of the leucocytes in 80% of the cases ranges within the normal limits. Eosinophilia is observed in 15% of the cases. 2. Anemia-producing substance in the serum of rheumatoid arthritis When serum from rheumatoid arthritis patients was injected into rabbits, the number of erythrocytes and the hemoglobin -content of the rabbits was found to decrease markedly for 2~6hours after the injection. But no such effect was observed when the serum of healthy subjects was injected. From this, the author presumes the presence of an anemia-producing substance in the serum of rheumatoid arthritis. The nature of this substance in now under investigation. II. Clinical-biochemical studies 3. Gastric acidity of rheumatic patients Of 7 cases examined, anacidity of gastric juice was observed in 2 cases, subacidity in other 2 cases and normacidity in the remaining 3 cases. Thus, a decrease in the gastric acidity was found to occur in 57% of the cases. 4. Takata-serum-test and sedimentation rate It is said that the sedimentation rate and the Weltmann-reaction are very sensitive indicators of the extent of the activity of rheumatic disease. The Takata-serum-test was applied in 18 cases and was found to give positive results in 10 cases (55%). The sedimentation rate was found to increase in 17 of 20 cases (85%). 5. Blood uric acid As is well known, the concentration of uric acid is abnormally high in the blood of patients with gout; while, according to the literature, the blood uric acid levels of patients with rheumatoid arthritis range within the normal limits. The author, using the method of Benedict, obtained the following results for blood uric acid in 14 normal subjects in fasting state: Range - 2.30~3.47mg./dl. , 5% rejection limit -- 1.97~3.68mg./dl. In 5 of 7 cases of rheumatoid arthritis, the blood uric acid levels were shown to be above the upper limit of the normal range, but the concentrations of blood uric acid of non-rheumatic joint diseases and neuralgias were mostly within the normal range. 6. Blood sugar The fasting blood sugar levels of rheumatoid patients ranged from 82 to 1l0mg./dl. (average : 100mg./dl.), higher than the levels of healthy subjects (78~108mg./dl., average : 90mg./dl.). The intravenously injected glucose load test was applied to 8 rheumatoid patients. A solution of 40 ml. of 20% glucose was injected into a fasting subject for 2 minutes. Blood samples were taken before the injection, 3 minutes after the injection, and at each subsequent 10 minute-interval for 70 minutes. The glucose tolerance curves in 5 of these cases were found to be out of the normal range. It is to be noticed that the average blood sugar for rheumatoid arthritis is similar to the curve for liver disease. 7. Serum alkaline phosphatase activity and serum phosphorus The method of Taussky-Shorr was used for the determination of the level of alkaline phosphatase activity and inorganic phosphate in the serum. The alkaline phosphatase activity of 11 normal individuals ranged from 1.4 to 6.4 Shinowara-Jones-Rheinhart units/dl. (5% rejection limit), while in 4 of 8 cases of rheumatoid arthritis, it was of abnormally high levels. The concentration of inorganic phosphate in the serum of 12 normal subjects ranged from 2.9 to 5.0mg. /dl. (5% rejection limit), while in 3 cases of rheumatoid patients, it showed higher levels than normal. 8. Total cholesterol in serum The total cholesterol in the serum of fasting normal individuals was measured by Bloor's method, and the concentration was found to range from 124 to 188mg./dl. (rejection limit of 5% level of significance), and the total cholesterol in the serum of rheumatoid arthritis to be abnormally high in concentration in 6 of 7 cases. The liver function was evaluated by the Takata-serum-test, the test of fasting blood sugar levels, the glucose load test, and the test of serum alkaline phosphatase activity; and from this the hepatic dysfunction was found to occur in rheumatoid arthritis patients in about 50% of the cases examined. Disturbances in the protein, fat, and carbohydrate metabolism were also found to occur. The above-mentioned findings indicate that rheumatoid arthritis is not only a disease of the joints, but also a general and systemic illness. Attention must accordingly be given to the general condition of the patient in the treatment of rheumatic disease.
出版物タイトル 岡山大学温泉研究所報告
発行日 1956-01
16巻
開始ページ 35
終了ページ 48
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40318
言語 日本語
論文のバージョン publisher
NAID 40017532470
JaLCDOI 10.18926/40321
タイトル(別表記) SEASONAL VARIATION OF GASTRIC ACIDITY
フルテキストURL pitsr_016_031_034.pdf
著者 森永 寛|
抄録 Since, in Japan situated in the temperate zone, climatic change through the four seasons of a year is regular, it is expected that there the physiological reactions of the human body may vary regularly in accordance with the climatic change. In fact, we experience that the attacks of diseases and their conditions are in close connection with the changes of the seasons. The author investigated the effect of the seasons upon the human gastric acidity, by means of the coffein-test, in 580 cases with gastrointestinal disorders, at the Misasa Branch Hospital of Okayama University, Misasa Spa in Tottori Prefecture, in 1946~1946. Hyperacidity was verified in 194 (33%) of 580 cases, normacidity in 134 (23%), anacidity in 138 (24%) and hypacidity in 114 (20%). The percentage of hyperacidity increases in winter (41%), decreases in spring (32%) and in summer (28%), and increases again in autumn (34%). The cases of anacidity decrease in winter and spring, but increase in summer. In chi-square test, the season and the acidity of gastric juice were taken as factors of variation. The chi-square was computed with the result: Pr {X(3)=14.013<16.919} =5%, so it cannot be asserted that the seasonal changes effect the acidity of gastric juice. But if Comparison is made between summer and winter with respect to the anacidity-hypacidity vs. the hyperacidity, the author: obtains Pr {X(2)=6.06> 5.412} =2%. It is thus verified that the cases of hyperacidity predominate over those of anacidity-hypacidity in winter, while the relation is reverse in summer. As was mentioned above, the tendency is obvious that the acidity of gastric juice decreases in summer and increases in winter. It was found that there is a regular seasonal variation in gastric acidity.
出版物タイトル 岡山大学温泉研究所報告
発行日 1956-01
16巻
開始ページ 31
終了ページ 34
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40318
言語 日本語
論文のバージョン publisher
NAID 120002462901
JaLCDOI 10.18926/40320
タイトル(別表記) ANEMIA-PRODUCING SUBSTANCE IN RHEUMATOID ARTHRITIS
フルテキストURL pitsr_016_019_030.pdf
著者 岸田 専蔵|
抄録 The anemia that usually accompanies rheumatoid arthritis has been thought to be caused by an infection of unknown etiology. The author found from his experiment that a temporary anemia is caused in rabbits by the injection of the serum of patients with rheumatoid arthritis into them, but no such effect by the injection of the serum of healthy subjects. The author presumes the existance of an anemia-producing substance in the serum of the rheumatoid arthritis. The nature of this substance is now under investigation.
出版物タイトル 岡山大学温泉研究所報告
発行日 1956-01
16巻
開始ページ 19
終了ページ 30
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40318
言語 日本語
論文のバージョン publisher
NAID 120002462900
JaLCDOI 10.18926/40319
タイトル(別表記) REPORT OF THE CHEMICAL ANALYSIS OF MISASA HOT SPRINGS, TOTTORI PREFECTURE
フルテキストURL 016_001_018.pdf
著者 大島 良雄| 御船 政明| 山田 尚春| 上山 昭子|
抄録 The water samples of 55 springs of Misasa were analysed in the years 1950~1951. The temperatures of the waters ranged from 44° to 85° C. Radon content ranged from 34.1 to 2360×10(-10) curies per liter. pH 6.2~7.5. Evaporation residue: 534~1940 mg/kg. K(+) :10.4~47.3mg/kg. Na(+) : 140.4~574mg/kg. Ca(2+) : 7.56~49.06mg/kg. Mg(2+) : 0.11~15.3mg/kg.. Fe(2+) : 0.10~0.67mg/kg. Cl(-) : 138~854mg/kg. SO(4)(2-) : 29.2~187mg/kg. HCO(3)(-) : 74.8~370mg/kg. HBO(2)(-) : 1.80~19.6mg/kg. S(2)O(3)(2-) : o.62~3.69mg/kg. Radon sources seem to exist at shallow places under the ground and the radon in the thermal wacer is supposed to have been derive partly from the ground water which also contains considerable amount of radon. A close linear correlation (r=0.751) was proved between the sulfate and the chloride ion contents.
出版物タイトル 岡山大学温泉研究所報告
発行日 1956-01
16巻
開始ページ 1
終了ページ 18
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40318
言語 日本語
論文のバージョン publisher
NAID 40017532473