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ID 41021
フルテキストURL
71_4561.pdf 1.04 MB
タイトル(別表記)
Morphological Studies on Human Ascites Tumor Cells by Tissue Culture Part 3. Influences of anticancerogenic agents on human ascites tumor cells
著者
浅香 隆一 岡山大学平木内科
抄録
By performing the tissue culture of cell suspension similarly as in Part 2, using the cells in ascites of the patients with coelothelioma but loading five anticancerogenic agents such as colcemide, carzinophilin, glucosamine, nitromine and unsaturated fatty acid extract of roentgenized liver (Yamamoto) the author carried out a series of observations on the morphological changes of the cells under culture and also compared the anticancerogenic mechanism of each of these drugs. The following are the results. 1) In the case loaded with colcemide a marked degeneration of cytoplasma and the abnormality in cell division can be recognized. 2) In the case loaded with carzinophilin the pyknosis and disintegration of the nucleus and cytoplasma can be observed. 3) In the case loaded with glucosamine the same as in (2), the pyknosis and disintegration of the nucleus and cytoplasma can be seen. 4) In the case of nitromine, the swelling and destruction of the nucleus and cytoplasma as well as the formation of bubbles can be recognized. 5) In the case loaded with unsaturated fatty acid extract of the roentgenized liver, the pyknosis and disintegration of the nucleus and the disintegration and swelling of cytoplasma, namely, the mechanism acting in two ways as carzinophilin and nitromine combined, can be recognized. As can be seen from above, it has been confirmed that the anticancerogenic mechanism of each of these drugs is characteristic respectively.
発行日
1959-08-10
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
71巻
8-1号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
4561
終了ページ
4569
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/71/8-1/71_8-1_4561/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
日本語
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma