癌毒素の骨髄に及ぼす影響 第2編 肝臓及び脾臓の関与と癌毒素の作用に関する実験的研究

It has been confirmed by many authorities that the liver and spleen play an important role on production of anemic-factor in development of anemia by various agents. However, no studies are found regarding cancer toxin. To disclose the anemia-producing action of cancer toxin an experiment irrigating the liver and spleen by extract of cancerous tissue obtained from stomach cancer has been performed. No significant fluctuations between the blood pictures of portal and hepatic veins following irrigation of cancer extract into the portal vein of rabbit is noticeable. Serum of hepatic venous blood obtained during lirer irrigation by cancer extract produces decrase of red cells (12.9% -14% ) in nutritional vein by one to two hours irrigation into femur marrow of normal rabbit. The same result is obtained in the case of spleen irrigation, too. It will be believed, after all, that the liver and the spleen form anemia-producing substances by influence of cancer toxin and they play significant roles on develo-pment of anemia in cancer patients.