Allerglic histological changes in the pregnant rabbit organs induced by injection of the globulin fractions from human placenta,pt.2.

The soluble protein, whole soluble protein, globulin and albumin fraction from human placenta, both normal and toxemic, have been introduced repeatedly into normal and pregnant rabbits and histological changes in the liver were observed. The striking changes in the liver have been induced by treating the animals with the globulin fraction and histologic pictures suggest that the toxemic liver damage is of allergic nature.