ID | 18179 |
Eprint ID | 18179
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フルテキストURL | |
タイトル(別表記) | Studies on (90)YCl(3) Colloid for Clinical Use Part I. Purification of (90)YCl(3) Colloid by Milking Method and the Observation of Electrone Microscopy
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著者 |
立花 明久
岡山大学医学部第1外科教室
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抄録 | (90)Y is a high-energy radioisotope and emite β-ray with 2.6 days half life. (90)YCl(3) colloid has been used for malignant tumor therapeutically, as (198)Au colloid. In the present experiment, the purification of (90)Y, and the detection of the contaminated (90)Sr was studied. Amberlite XE-100 column was suitable for this prupose. The colloidal size of (90)YCl(3) was transformed by pH, and the features of (90)YCl(3) colloids were observed on electrone microscope. 1) (90)Y and (90)Sr mixture adsorbed on Amberlite XE-100 column (100-200 mesh, 2.5 column volume), and eluted by 0.5 N HCl. (90)Sr is eluted out at 10-60 ml, and (90)Y is eluted out from 170 ml. 2) A mixture of 20 mC of citrate-(90)Y complex and 1μC of (90)Sr fixed on this column, and then eluted by 0.5 N HCl. One drop of eluate at 10 ml was detectable by GM counter. The detectable lower limit of contaminated (90)Sr is 0.1μC by re-counting on GM counter 24 hrs after the elution. 3) Amberlite XE-100 column is suitable for the second column on the milking system, for the purpose of separating the contaminated (90)Sr and (90)Y. This procedure is complete in 1 hr process. 4) (90)YCl(3) colloid is aggregated and formed clamp in high pH solution, Electrone microscopic observations showed that the colloidal size was 40-50 mμ at pH 5, and 20 mμ at pH7.
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発行日 | 1968-12-30
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出版物タイトル |
岡山医学会雑誌
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出版物タイトル(別表記) | Journal of Okayama Medical Association
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巻 | 80巻
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号 | 11-12号
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出版者 | 岡山医学会
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出版者(別表記) | Okayama Medical Association
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開始ページ | 1091
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終了ページ | 1103
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ISSN | 0030-1558
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NCID | AN00032489
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資料タイプ |
学術雑誌論文
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オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/80/11-12/80_11-12_1091/_article/-char/ja/
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関連URL | http://www.okayama-u.ac.jp/user/oma/
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言語 |
日本語
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著作権者 | 岡山医学会
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論文のバージョン | publisher
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査読 |
有り
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Eprints Journal Name | joma
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