検索結果 942 件
| JaLCDOI | 10.18926/AMO/40508 |
|---|---|
| フルテキストURL | 64_5_323.pdf |
| 著者 | Kanaoka, Yuji| Inagaki, Ei-ichirou| Hamanaka, Souhei| Masaki, Hisao| Tanemoto, Kazuo| |
| 抄録 | The transient systemic low perfusion that occurs during cardiovascular surgery leads to oxidative stress and the production of free radicals. A systemic increase of various markers of oxidative stress has been shown to occur during cardiopulmonary bypass (CPB). However, these markers have not been adequately evaluated because they seem to be reactive and short-lived. Here, oxidative stress was measured using the free radical analytical system (FRAS 4) assessing the derivatives of reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP). Blood samples were taken from 21 patients undergoing elective cardiovascular surgery. CPB was used in 15 patients, and abdominal aortic aneurysm (AAA) surgery without CPB was performed in 6. Measurements of d-ROMs and BAP were taken before surgery, 1 day, 1 week, and 2 weeks after surgery, and oxidative stress was evaluated. The d-ROM level increased gradually after cardiovascular surgery up to 2 weeks. Over time, the d-ROM level after surgery involving CPB became higher than that after AAA surgery. This difference reached statistical significance at 1 week and lasted to 2 weeks. The prolongation of CPB was prone to elevate the d-ROM level whereas the duration of the aortic clamp in AAA surgery had no relation to the d-ROM level. The BAP was also elevated after surgery, and was positively correlated with the level of d-ROMs. In this study, patients who underwent cardiovascular surgery involving CPB had significant oxidative damage. The production of ROMs was shown to depend on the duration of CPB. Damage can be reduced if CPB is avoided. When CPB must be used, shortening the CPB time may be effective in reducing oxidative stress. |
| キーワード | oxidative stress reactive oxygen metabolites (ROM) extracorporeal circulation (ECC) |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2010-10 |
| 巻 | 64巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 323 |
| 終了ページ | 330 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2010 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 20975766 |
| Web of Science KeyUT | 000283563300008 |
| JaLCDOI | 10.18926/40432 |
|---|---|
| タイトル（別表記） | MEDICAL STUDIES ON CHONDROITlN SULFATE (IV) DISTRIBUTION OF CHONDROITIN SULFATE LABELED WITH S(35) IN ANIMAL BODY |
| フルテキストURL | pitsr_012_042_051.pdf |
| 著者 | 岸田 專蔵| |
| 抄録 | 0.1 ml. of the 1% solution of chondroitin sulfate labeled with S(35) was administered to mice intraperitoneally or 0.5 ml. was given per orally with gastric tube to another gronp of mice. Each two mice were killed every one, two, six, twelve, twenty four and fouty eight hours after the injection respectively and after a series of daily injection for a week samples of blood, lungs, heart, liver, kidneys, skin, muscles bones, spleen, brain, stomach and ntestines were taken from these animals. Radioactivity of S(35) was measured by BaSO(4) method using Lanritsen's electroscope. 1) The highest activity in blood was observed by about two hours after the injection, while in per oral administration it was reached after six hours. absorption of perorally administered chondroitin sulfate was estimated to reach roughly 35% abter 6 hours. 2) The excretion of labeled chondroitin sulfate seemed to be done from kidneys. The greater part was excreted in six hours and then the decrease in the activity of kidneys became slower. 3) Muscles and skin showed a considerable activity in 1-2 hours. A marked decrease was seen after six hours, then their activity seemed to remain unchanged. 4) Radioactivity of skeleton rose gradually, reached its maximum in twelve hours, and then had a tendency to show constant value. 5) In liver, spleen and brain highest activity was observed two hours after the injection. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-09 |
| 巻 | 12巻 |
| 開始ページ | 42 |
| 終了ページ | 51 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40422 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002509308 |
| JaLCDOI | 10.18926/40413 |
|---|---|
| タイトル（別表記） | STUDIES ON THE AGING OF MINERAL WATERS (II) CHANGES IN THE SILICATE CONTENT OF THERMAL WATERS OF MISASA AFTER FLOWING OUT |
| フルテキストURL | pitsr_011_014_018.pdf |
| 著者 | 杉原 健| |
| 抄録 | The author determined the silicate content of the thermal water of Hisui-no-Yu, Misasa, Tottori Prefecture, Japan, at varying times after flowing out, and obtained the following results: 1) The change in the silicate content after flowing out is at first remarkable. 2) The velocity of the changes in the silicate content has a tendency to be faster in the sample that is kept in the vessel with a wide water surface than in the one that has a smaller surface. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-06 |
| 巻 | 11巻 |
| 開始ページ | 14 |
| 終了ページ | 18 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40410 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002509298 |
| JaLCDOI | 10.18926/40383 |
|---|---|
| タイトル（別表記） | ON THE DETECTION OF RADIOACTIVE SPRING BY GROUND WATER |
| フルテキストURL | 009_037_042.pdf |
| 著者 | 杉原 健| |
| 抄録 | The author determined the radon content in the ground waters of Misasa and its vicinity by the I. M. fontactoscope from August to November, 1952. The results and conclusions are as follocvs : A close correlation was observed between the radon contents in the spring-waters and that in the ground-waters near the springs, so it seems possible to prospect the existence of radioactive springs by determination of the radon content in groundwaters in the place where no radioactive spring was found as yet. The highest radon content in 53 samples was 741 Mache (2697×10(-10) Curie/l) of the Mr, shigemasa Matsubara's well-water, and this record ecceeds the highest radon content in thermal waters of Misasa known up to the present time. Though the temperature of its well-water was 24.0°C in the afternrnoon of November 25th, 1952, the hot-springs of Yamadaku-kyodoYu, Gunzeshinsenryo, Koyoen, and so on, issue neare by the well. Therefore, the author points out that if a boring is tried in the place where the well is the centre, a most strongly radioactive hot spring in the world may issue. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-01 |
| 巻 | 9巻 |
| 開始ページ | 37 |
| 終了ページ | 42 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532515 |
| JaLCDOI | 10.18926/40382 |
|---|---|
| タイトル（別表記） | ON THE DISTRIBUTION OF THE NITRATE CONTENT IN THE MISASA HOT SPRINGS, TOTTORI PREFECTURE |
| フルテキストURL | 009_032_036.pdf |
| 著者 | 杉原 健| |
| 抄録 | The author determined the nitrate content in Misasa Hot-Springs, sampled from August to October, 1952, In all the well-waters, the amounts of nitrate were higher than 1mg/l, and the highest nitrate content was 9.6mg/l in the well-water in front of Mr. Aoki, s house. In the hot-springs, the author found 10 springs containing more than 1 mg/l of nitrate, and the highest nitrate content was 9.0 mg/l in the Hakuro-Yu, but the lotvest content was about 0 mg/l in the Iwasaki Hot-Springs. In Ishiyu and "Yamadaku-KyodoYu" during the stay of irrigation water in rice-fields from the rain season to September, the amounts of flow incrensed, but the content of radon and chloride decreased. On the other hand, in Hisui-no-yu, the chloride content decreased and the radon content increased with the amount of flow. Moreover, the amounts of nitrate were considerably high in the Ishiyu and Yamndaku-KyodoYu Hot Springs, but fairly low in the Hisui-no-Yu. So the author expects that some relation may be found between the variation of the radon content and the amounts of nitrate. The water samples, which nitrate contents were high, showed a tendency to have a high phosfate content generally. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-01 |
| 巻 | 9巻 |
| 開始ページ | 32 |
| 終了ページ | 36 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532514 |
| JaLCDOI | 10.18926/40380 |
|---|---|
| タイトル（別表記） | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (VI) DISTRICT NEAR THE SPRING IN KITADANI VILLAGE, TOTTORI PREFECTURE, JAPAN |
| フルテキストURL | 009_024_027.pdf |
| 著者 | 梅本 春次| |
| 抄録 | In Fukudome, Kitadani Village, the chloride, sulfate and phosfate content and water temperatures of well waters and the amounts of chloride and sulhte fixed to the soil were determined with the samples collected from various parts near the spring which contains much inorganic salts. The chloride, sulfate and phosfate content of the well water samples collected from the district which surrounds the spring, were higher than those from its neighhonrhood, but for the water temperatures of the well water samples, no difference was recognized. As the existence of other sources which would supply the chloride, sulthte and phosfate to the well water is not expected, the difference in the chloride, sulfate and phosfate content of well waters between the samples collected from the A district and its neighbourhood, seems to be due to the effects of the spring which contains much inorganic salts or its sources. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-01 |
| 巻 | 9巻 |
| 開始ページ | 24 |
| 終了ページ | 27 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532512 |
| JaLCDOI | 10.18926/40379 |
|---|---|
| タイトル（別表記） | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (V) HAMAMURA AND KACHIMI HOT-SPRINGS, TOTTORI PREFECTURE, JAPAN |
| フルテキストURL | 009_020_023.pdf |
| 著者 | 梅本 春次| |
| 抄録 | In Hamamura and Kachimi Hot-Springs, the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from vmions parts of the mineral spring districts. The chloride and sulfate content and warter temperatures of well waters were higher in the samples collected from the thermal spring districts than in the samples collected from its neighbourhood, but for the amounts of chloride and sulfate fixed to the soil, no difference was recognized. As the existence of other sources whlch would supply the chloride, sulfate and heat to the well waters is not expected, the difference in the chloride and sulfate content and water temperatures of well waters, between the samples collected from the thermal spring districts and its neighbourhood, seems to he due to the effects of the thermal springs. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-01 |
| 巻 | 9巻 |
| 開始ページ | 20 |
| 終了ページ | 23 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532512 |
| JaLCDOI | 10.18926/40378 |
|---|---|
| タイトル（別表記） | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (IV) TAMATSUKURI HOT-SPRINGS, SHIMANE PREFECTURE, JAPAN |
| フルテキストURL | 009_016_019.pdf |
| 著者 | 梅本 春次| |
| 抄録 | In Tamatsukuri Hot-Springs, the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from various parts of the mineral spring districts. For the values which were determined with samples collected from the thermal spring districts and its neighbourhood, no difference was recognized. This result is quite different from the results given in the previous reports of the present author. But this fact may be explaned as the effects of the sea warter, and the further study is being continued. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-01 |
| 巻 | 9巻 |
| 開始ページ | 16 |
| 終了ページ | 19 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532512 |
| JaLCDOI | 10.18926/40377 |
|---|---|
| タイトル（別表記） | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (III) SIIGAKU AND YUGAKAI HOT-SPRINGS, SHIMANE PREFECTURE, JAPAN |
| フルテキストURL | 009_010_015.pdf |
| 著者 | 梅本 春次| |
| 抄録 | 1) In Shigaku Hot-Springs, the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from various parts of the thermal spring district and its neighbourhood. The amounts of chloride and sulfate fixed to the soil were greater in the samples from the thermal spring district than in those from its neighbourhood. As the existence of other sources which would supply the chloride and foulfate to the soil is not expected, the difference in the amounts of chloride and sulfate, between the samples from the thermal spring district and it; neighbourhood, seems to be due to the effects. of thermal springs. 2) In Yugakai Hot-Springs the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from various parts of the mineral spring district. The water temperatures of well water samples from the district which has the mineral springs with higher temperatures, were higher than those from the district which has the mineral springs with lower temperatures, but for the chloride and sulfate content of the well water samples and the amounts of chloride and sulfate fixed to the soil, no difference was detected. As the existence of other sources which would supply the heat to the water is not expected, the difference in the water temperatures, between the samples from the district which has the mineral springs with higher temperatures and the district which has the mineral springs with lower temperatures, seems to be due to the effects of the mineral springs. On the other hand, for the chloride and sulfate content of well water samples and the amounts of chloride and sulfate fixed to the soil, no difference is recognized. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-01 |
| 巻 | 9巻 |
| 開始ページ | 10 |
| 終了ページ | 15 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532512 |
| JaLCDOI | 10.18926/40376 |
|---|---|
| タイトル（別表記） | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (II) SEKIGANE HOT-SPRINGS, TOTTORI PREFECTURE, JAPAN |
| フルテキストURL | 009_006_009.pdf |
| 著者 | 梅本 春次| |
| 抄録 | In Sekigane Hot-Springs, the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from the various parts of the thermal spring district and its neighbourhood. The chloride and sulfate content of the well water samples collected from the thermal spring district were higher than those from its neighbourhood, and no difference was found for the water temperatures. The amonnts of chloride fixed to the soil in the samples collected from the thermal spring district were greater than those from its neighbourhood, and the amounts of sulfate in the samples collected from the thermal spring district were extremely greater than those from its neighhourhood. As the existence of other sources which would supply the chloride and sulfate to the water and soil is not expected, the difference in the chloride and sulfate content and water temperatures, between the sa.mples from the thermal spring district and its neighbourhood, seems to be due to the effects of thermal springs. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-01 |
| 巻 | 9巻 |
| 開始ページ | 6 |
| 終了ページ | 9 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532512 |
| JaLCDOI | 10.18926/40375 |
|---|---|
| タイトル（別表記） | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (I) MISASA HOT-SPRINGS, TOTTORI PREFECTURE, JAPAN |
| フルテキストURL | 009_001_005.pdf |
| 著者 | 梅本 春次| |
| 抄録 | In Misasa Hot-Springs, the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from various parts of the thermal spring district and its neighbourhood. The chloride and sulfate content and water temperatures of the well water samples collected from the thermal spring district were higher than those from its neibourhood, and the amounts of chloride fixed to the soil were greater in the samples collected from the thermal spring district than in those from its neighbourhood, but for the amounts of sulfate fixed to the soil, no difference was detected. As the existence of other sources which would supply the chloride and sulfate to the water and soil is not expected, the difference in the chloride and sulfate content and water temperatures, between the samples collected from the thermal spring district and its neighbourhood, seemes to be due to the effects of thermal springs. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-01 |
| 巻 | 9巻 |
| 開始ページ | 1 |
| 終了ページ | 5 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532512 |
| JaLCDOI | 10.18926/40364 |
|---|---|
| タイトル（別表記） | Direct colorimetric and volumetric determination of calcium with new reagent |
| フルテキストURL | rbl_003_039_042.pdf |
| 著者 | 芦澤 峻| |
| 抄録 | The anthor found that azocal-A reacts only with calcium, and devised a direct colorimetric, and a direct titration method for calcium determination using azocal-A as an indicator, and obtained a satisfactory result. Accuracy : detectable amount in NaOH……0.28 γ, of Ca ; detectable amount in NH(4)OH……2 γ, of Ca. Sensibility……1 : 125,000 & 1 : 17,500 respectively. Interfering substances : Fe, U, Ni, Co, Hg, Ag, citrate, tartarate, oxalate, large amount of NH(4) salts, Sr, Mg. Not interfering subst. : Ba, F, acetate and silicate. Reagents : Saturated soln. of azocal-A in weak NaOH soln.. Spot test procedure : Place a drop of the acid or neutral test soln. upon white spot plate, add 1 drop of azocal-A soln., and mix them. If a yellow color appears, calcium is present. Colorimetric method: Transfer water sample containg not more than 0.05 mg of calcium, and not more than 5 mg of Fe, Mn, Mg, etc. to a 20 cc colorimetric tube, add 0.5-1 cc of azocal-A soln. and 0.5 cc of 6N-NaOH soln.. Allow it to stand for 10 minutes. Then compare the resulted yellow color with standard Ca soln. prepared similarly and simultaneously. Volumetric method : Amount determinable : 0.1 g of calcium. Transfer 40 cc of sample containg 5-100 mg to a 100 cc Erlenmeyer's flask, add 0.5 cc of 6N-HCl, add azocal-A to the amount of pink color as caused by methyl orange in acid soln.. Make alkaline with 1 cc of 6N-NaOH. Add 10 cc alcohol to every 40 cc of the sample solution. Then its color turns to yellow. Titrate with 0.1 N oxalate soln.. 1.0 cc of 0.1 N oxalate soln. is equivalent to 2.0 mg of Ca. Absorption band of the acid soln. at 4900 A, alkaline soln. at 5000 A, Ca-compound at 4300 A. The azocal-A is o-carboxy-benzol-azo-2-naphtol 3, 6-disulfonic acid prepared from anthranilic acid and R-salt. |
| 出版物タイトル | 放射能泉研究所報告 |
| 発行日 | 1950-07-25 |
| 巻 | 3巻 |
| 開始ページ | 39 |
| 終了ページ | 42 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002484888 |
| JaLCDOI | 10.18926/40353 |
|---|---|
| タイトル（別表記） | STUDIES ON THE AGING OF THE MINERAL WATERS (Ill) VARIATION OF SILICATE IN THEMINERAL WATERS |
| フルテキストURL | pitsr_012_006_010.pdf |
| 著者 | 杉原 健| |
| 抄録 | When silicate content is determined by the colorimetric method, the silicate content in the mineral waters and sodium silcate solution decreases in addition of ammonium hydroxide and sodium carbonate respectively, and moreover after addition of aluminium ion in the samples, when aluminium hydroxide is precipitated from ammonium hydroxide solution, total silicates in various forms are coprecipitated with it. The silicate content in the mineral waters that are kept in concentrations of 0.1～0.4 normality of sodium hydroxide showed special variations with times. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-09 |
| 巻 | 12巻 |
| 開始ページ | 6 |
| 終了ページ | 10 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002484889 |
| JaLCDOI | 10.18926/40352 |
|---|---|
| タイトル（別表記） | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE A;\lD SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (VIII) MATSUZAKI, TOGO AND ASOZU HOT SPRINGS, TOTTORI PREFECTURE, JAPAN |
| フルテキストURL | 012_001_005.pdf |
| 著者 | 木村 健二郎| 梅本 春次| |
| 抄録 | In Matsuzaki, Togo and Asozu Hot Springs which issue around the Pond Togo, the chloride and sulfate content and water temperatures of well waters and the amount of chloride and sufate fixed to the soil were determined with samples collected from various parts of the thermal spring districts and its neighborhood. The chloride and sulfate content and water temperatures of the well water samples collected from the thermal spring districts were higher than those from its neighbourhood, but for the amounts of chloride and sulfate fixed to the soil, no difference was detected. As the existence of other sources which would supply the chloride, sulfate and heat to the water is not expected, the difference in the chloride and sulfate content and water temperatures of well waters, between the samples collected from the thermal spring districts and its neighbourhood, seems to be due to the effects of thermal springs. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-09 |
| 巻 | 12巻 |
| 開始ページ | 1 |
| 終了ページ | 5 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532436 |
| JaLCDOI | 10.18926/40344 |
|---|---|
| タイトル（別表記） | STUDIES ON VITRIOL SPRINGS (4) ON THE COPPER, ZINC, NICKEL, AND COBALT CONTENTS OF BLOOD AFTER THE INTERNAL USE OF A VITRIOL WATER |
| フルテキストURL | 013_015_017.pdf |
| 著者 | 大島 良雄| 芦沢 峻| |
| 抄録 | Sotozono proved that the administration of daily 20cc of Fujino Mineral Water (an acid vitriol water containing copper, zinc, nickel and cobalt) has a remarkably beneficial effect on several kinds of hypochromic anemia. It contains 9.56gms of iron, 0.007gm of zinc, 0.005gm of copper 0.001gm of nickel, and 0.006gm of cobalt in one liter. 20 - 40cc of Fujino water was diluted 5 - 10 fold with plain water and administered to the fasting patients perorally. Blood samples were taken from cubital vein before, 1, 2, 4, 6, 24, 48, and 72 hours after the intake of the vitriol water. Copper, zinc, nickel and cobalt contents of the blood samples were measured by Ashizawa' s dithizone- chromatographic method. It was shown that copper, nickel, and cobalt contents of blood rose unexpectedly high temporarily, in a manner that did not correspond to their amount in the given mineral water. So that the mobilization of copper, nickel, and cobalt in the body after the intake of the mineral IVrter was susrected. Zinc content of blood showed no constant tendency. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-12 |
| 巻 | 13巻 |
| 開始ページ | 15 |
| 終了ページ | 17 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002484879 |
| JaLCDOI | 10.18926/40342 |
|---|---|
| タイトル（別表記） | ON THE EXISTENCE OF RADIUM B, RADIUM C AND THORIUM B IN MISASA HOT SPRINGS |
| フルテキストURL | pitsr_013_005_008.pdf |
| 著者 | 佐藤 三雄| |
| 抄録 | The author tried to measure RaB, RaC and ThB in the hot spring waters using G-M counter and proved the existence of RaB and ThB in Misasa Hot Springs. To 100 liters of spring water ahout 20 gms of ferric chloride and then sodium hydroxide were added. Precipitate was dissolved in hydrochloric acid and after adding bismuth and lead, the solution was saturated with hydrogen sulfide. The precipitate of sulfides was filtered and ignited to ashes after drying. The β-activity of the ashes was measured by a mica-window type G-M counter with the recording circuits of scale of 16. Natural background was 50±5 connts per minutes. Six spring waters of Misasa, namely "Spring of Branch Laboratory", "Nakayu", "Gunze" "O-T-R", "Jwayu", and "Tsukiminoyu" were investigated. RaB was detected in all samples. ThB was found only in "Gunze" and "O-T-R". ThB content of "Gunze" was estimated, to be roughly 1×10(-12) Curie units per liter. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1953-12 |
| 巻 | 13巻 |
| 開始ページ | 5 |
| 終了ページ | 8 |
| ISSN | 0369-7142 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002484878 |
| JaLCDOI | 10.18926/40324 |
|---|---|
| タイトル（別表記） | RADON CONTENT OF HOT SPRINGS IN TOTTORI PREFECTURE, JAPAN |
| フルテキストURL | 014_001_014.pdf |
| 著者 | 大島 良雄| 山田 尚春| 御船 政明| |
| 抄録 | 1. Radon content of 166 thermal waters in IWAI, TOTTORI YOSHIOKA, HAMAMURA, TOGO, SEKIGANE, MISASA, and KAlKE Hot Springs was measured by I. M. Fontactoscope in the years 1950-1951. Of which 66 samples showed a radon content over 30×10(-10) curie units per liter. Namely, 50 springs in Misasa, 6 in Sekigane, 9 in Hamamura, and one in Togo belonged to the radioactive spring in the definition by Ministry of Social Welfare. The highest Radon content (1150×10(10) curie units per liter) was recorded in Hisuino-Yu in Misasa, where five springs had a radon content over 360×10(-10) curie units per liter. 2. No marked difference was proved between the results obtained this time and the data in the former reports concerning the radon content of these thermal springs. 3. Radon content proved higher in the springs which issue from granite than in the springs of other districts. No definite relation was proved between the radon content and water temperature. The radon content was generally high in simple thermals or in weak sodium chloride springs, low in sulfated springs and in saline springs which had a comparatively high sulfate content. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1954-03 |
| 巻 | 14巻 |
| 開始ページ | 1 |
| 終了ページ | 14 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532457 |
| JaLCDOI | 10.18926/40322 |
|---|---|
| タイトル（別表記） | THE CLINICAL STUDIES OF RHEUMATOID ARTHRITIS (I) |
| フルテキストURL | 016_035_048.pdf |
| 著者 | 森永 寛| |
| 抄録 | The value of spa treatment of rheumatic disease is an established feature of medical management based on experiences for many centuries. The author has been practising the balneotherapy of rheumatic diseases at Misasa Spa for several years, and has found this therapy efficacious in many cases in relieving the anemia that accompanies rheumatoid arthritis. For this reason, the author is investigating the metabolism of iron in rheumatic anemia, which is expected to occur in the course of the spa treatment. In this report, the results of clinical examinations of 24 patients with rheumatoid arthritis, of the type (2. 2. 2.) Polyarthritis systemica chronica (in Prof. Kodama's classification of arthritis), are described. I. Some observations of anemia in rheumatoid arthritis 1. The peripheral blood The number of erythrocytes is 266×10(4)～455×10(4)/c. mm. (average: (381±32)×10(4)/c. mm.), Hb-content : 55～90% (average : 76±5.8%), and the color index is about 1.0. The anemia of rheumatic disease treated is mostly normochromic. The white blood count is between 3240 and 13300/c. mm. (average: 6421±955/c. mm. ), and the number of the leucocytes in 80% of the cases ranges within the normal limits. Eosinophilia is observed in 15% of the cases. 2. Anemia-producing substance in the serum of rheumatoid arthritis When serum from rheumatoid arthritis patients was injected into rabbits, the number of erythrocytes and the hemoglobin -content of the rabbits was found to decrease markedly for 2～6hours after the injection. But no such effect was observed when the serum of healthy subjects was injected. From this, the author presumes the presence of an anemia-producing substance in the serum of rheumatoid arthritis. The nature of this substance in now under investigation. II. Clinical-biochemical studies 3. Gastric acidity of rheumatic patients Of 7 cases examined, anacidity of gastric juice was observed in 2 cases, subacidity in other 2 cases and normacidity in the remaining 3 cases. Thus, a decrease in the gastric acidity was found to occur in 57% of the cases. 4. Takata-serum-test and sedimentation rate It is said that the sedimentation rate and the Weltmann-reaction are very sensitive indicators of the extent of the activity of rheumatic disease. The Takata-serum-test was applied in 18 cases and was found to give positive results in 10 cases (55%). The sedimentation rate was found to increase in 17 of 20 cases (85%). 5. Blood uric acid As is well known, the concentration of uric acid is abnormally high in the blood of patients with gout; while, according to the literature, the blood uric acid levels of patients with rheumatoid arthritis range within the normal limits. The author, using the method of Benedict, obtained the following results for blood uric acid in 14 normal subjects in fasting state: Range - 2.30～3.47mg./dl. , 5% rejection limit -- 1.97～3.68mg./dl. In 5 of 7 cases of rheumatoid arthritis, the blood uric acid levels were shown to be above the upper limit of the normal range, but the concentrations of blood uric acid of non-rheumatic joint diseases and neuralgias were mostly within the normal range. 6. Blood sugar The fasting blood sugar levels of rheumatoid patients ranged from 82 to 1l0mg./dl. (average : 100mg./dl.), higher than the levels of healthy subjects (78～108mg./dl., average : 90mg./dl.). The intravenously injected glucose load test was applied to 8 rheumatoid patients. A solution of 40 ml. of 20% glucose was injected into a fasting subject for 2 minutes. Blood samples were taken before the injection, 3 minutes after the injection, and at each subsequent 10 minute-interval for 70 minutes. The glucose tolerance curves in 5 of these cases were found to be out of the normal range. It is to be noticed that the average blood sugar for rheumatoid arthritis is similar to the curve for liver disease. 7. Serum alkaline phosphatase activity and serum phosphorus The method of Taussky-Shorr was used for the determination of the level of alkaline phosphatase activity and inorganic phosphate in the serum. The alkaline phosphatase activity of 11 normal individuals ranged from 1.4 to 6.4 Shinowara-Jones-Rheinhart units/dl. (5% rejection limit), while in 4 of 8 cases of rheumatoid arthritis, it was of abnormally high levels. The concentration of inorganic phosphate in the serum of 12 normal subjects ranged from 2.9 to 5.0mg. /dl. (5% rejection limit), while in 3 cases of rheumatoid patients, it showed higher levels than normal. 8. Total cholesterol in serum The total cholesterol in the serum of fasting normal individuals was measured by Bloor's method, and the concentration was found to range from 124 to 188mg./dl. (rejection limit of 5% level of significance), and the total cholesterol in the serum of rheumatoid arthritis to be abnormally high in concentration in 6 of 7 cases. The liver function was evaluated by the Takata-serum-test, the test of fasting blood sugar levels, the glucose load test, and the test of serum alkaline phosphatase activity; and from this the hepatic dysfunction was found to occur in rheumatoid arthritis patients in about 50% of the cases examined. Disturbances in the protein, fat, and carbohydrate metabolism were also found to occur. The above-mentioned findings indicate that rheumatoid arthritis is not only a disease of the joints, but also a general and systemic illness. Attention must accordingly be given to the general condition of the patient in the treatment of rheumatic disease. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1956-01 |
| 巻 | 16巻 |
| 開始ページ | 35 |
| 終了ページ | 48 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40318 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532470 |
| JaLCDOI | 10.18926/40319 |
|---|---|
| タイトル（別表記） | REPORT OF THE CHEMICAL ANALYSIS OF MISASA HOT SPRINGS, TOTTORI PREFECTURE |
| フルテキストURL | 016_001_018.pdf |
| 著者 | 大島 良雄| 御船 政明| 山田 尚春| 上山 昭子| |
| 抄録 | The water samples of 55 springs of Misasa were analysed in the years 1950～1951. The temperatures of the waters ranged from 44° to 85° C. Radon content ranged from 34.1 to 2360×10(-10) curies per liter. pH 6.2～7.5. Evaporation residue: 534～1940 mg/kg. K(+) :10.4～47.3mg/kg. Na(+) : 140.4～574mg/kg. Ca(2+) : 7.56～49.06mg/kg. Mg(2+) : 0.11～15.3mg/kg.. Fe(2+) : 0.10～0.67mg/kg. Cl(-) : 138～854mg/kg. SO(4)(2-) : 29.2～187mg/kg. HCO(3)(-) : 74.8～370mg/kg. HBO(2)(-) : 1.80～19.6mg/kg. S(2)O(3)(2-) : o.62～3.69mg/kg. Radon sources seem to exist at shallow places under the ground and the radon in the thermal wacer is supposed to have been derive partly from the ground water which also contains considerable amount of radon. A close linear correlation (r=0.751) was proved between the sulfate and the chloride ion contents. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1956-01 |
| 巻 | 16巻 |
| 開始ページ | 1 |
| 終了ページ | 18 |
| ISSN | 0369-7142 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/40318 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532473 |
| JaLCDOI | 10.18926/40272 |
|---|---|
| タイトル（別表記） | THE CHANGE IN CONCENTRATION OF FERROUS IRON AND REDUCIBLE IRON, DISSOLVED IN SPRING WATER AT MISASA HOT SPRINGS, JAPAN, DURING PRESERVATION OF THE WATER SAMPLE IN A SEALED BOTTLE |
| フルテキストURL | pitsr_020_048_054.pdf |
| 著者 | 田中 重男| |
| 抄録 | The two sprigns called "Tanaka-no-Yu" and "Hisui-no-Yu" at Misasa Hot Springs, japan (Fig. 1), suitable for sampling the unpolluted water, the locations of which, are shown in Fig. 2, were chosen for this study. The o-phenanthroline method, details of which were discussed in the previous report by the author (Repts. Balneol. Lab. Okyama Univ., 17, 1, (1956)) was used for the determination of ferrous iron, ferrous iron + reducible iron, and ferrous iron + reducible iron + colloidally dispersed iron (to be referred to as "total irons" in this report). For comparison, the change in concentratin of iron dissolved in distilled water during preservation in a sealed bottle was observed, and the results obtained for the solutions with the pH values of 5.4 and 5.8 are illustrated in Fig.3 and Fig.5, rspectively. Both ferrous and reducible iron disappear within 5 minutes, when the pH of the solution is 6.4. The hydrogen ion concentration was thus seen to give a sensitive effects on the speed of diminution of ferrous and reducible iron dissolved in the distilled water. It should be noticed that no appreciable diminution was observed during the period from 60 min. to 120 min,. It is probable that the diminution of total iron is caused by the adsorption of colloidal iron hydroxides on the wall of glass bottle. The effects of charged anion (SO(4)(--)) on the change in concentration of iron during preservation was also investigated, but no appreciable effect was found. (Fig. 5 and Fig. 6). Fig.7, Fig.8, and Fig.9 show the change in concentration of iron during preservation of the spring water at "Tanaka-no-Yu". The content of iron in the spring water is about 0.3 mg/l, and its pH value is about 7.1. For the first 30 minutes, ferrous iron diminishes rapidly, the slope of the diminution curve being sharp and almost straight. Thereafter the slope becomes gentler, and, after an hour, the slope approaches nearly zero. On the other hand, ferrous iron dissolved in distilled water disappears in a moment at the same pH 7.1. Fig.10, Fig.11, and Fig.12 show the change in concentration of iron during preservation of the spring water at "Hisui-no-Yu". The content of iron in the spring water is about 1.0 mg/l, and its pH value is about 6.4. In this case, the diminution of ferrous iron is not remarkable, and only 20% of the initial quantity diminishes within 2 days. Whereas, in the case of distilled water, the diminution is very rapid at the same pH 6,4, and the ferrous iron disappears completely within 5 minutes. In Fig.13 the speed of diminution of iron in distilled water and that in spring water are compared. The difference here seen may probably be due either to that the ferrous iron in spring water is in a certain complex form not easily oxidizable, or to that the spring water contains some reducing substances. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1958-01 |
| 巻 | 20巻 |
| 開始ページ | 48 |
| 終了ページ | 54 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002462895 |