検索結果 3336 件
| フルテキストURL | K0007096_abstract_review.pdf K0007096_fulltext.pdf K0007096_summary.pdf |
|---|---|
| 著者 | 富永 悠介| |
| 発行日 | 2024-09-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第7096号 |
| 学位授与年月日 | 2024-09-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| 著作権者 | © 2024 American Society of Andrology and European Academy of Andrology. |
| フルテキストURL | K0007088_abstract_review.pdf K0007088_fulltext.pdf K0007088_other.pdf K0007088_summary.pdf |
|---|---|
| 著者 | 宮原 大輔| |
| 発行日 | 2024-09-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第7088号 |
| 学位授与年月日 | 2024-09-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| 著作権者 | © 2023 Wiley Periodicals LLC. |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Higo, Hisao| Ichikawa, Hirohisa| Arakawa, Yukako| Mori, Yoshihiro| Tamura, Tomoki| Kuyama, Shoichi| Matsumoto, Chiaki| Sugimoto, Keisuke| Hamada, Noboru| Suwaki, Toshimitsu| Itano, Junko| Tanimoto, Yasushi| Senoo, Satoru| Taniguchi, Akihiko| Inukai, Yumi| Arita, Machiko| Makimoto, Satoko| Kojima, Katsuhide| Matsushita, Takashi| Maeda, Yoshinobu| Miyahara, Nobuaki| |
| キーワード | interstitial pneumonia with autoimmune features cryptogenic organizing pneumonia bronchoalveolar lavage prospective multicenter observational study connective tissue disease |
| 発行日 | 2024-11-15 |
| 出版物タイトル | Journal of Clinical Medicine |
| 巻 | 13巻 |
| 号 | 22号 |
| 出版者 | MDPI |
| 開始ページ | 6870 |
| ISSN | 2077-0383 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/jcm13226870 |
| Web of Science KeyUT | 001365308300001 |
| 関連URL | isVersionOf https://doi.org/10.3390/jcm13226870 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Enomoto, Shota| Furuuchi, Shunya| Ishibashi, Tatsuki| Yamada, Shu| Oda, Toshiaki| |
| キーワード | achilles tendon computational model small composite design subtendon tendinopathy |
| 発行日 | 2024-10-31 |
| 出版物タイトル | Frontiers in Bioengineering and Biotechnology |
| 巻 | 12巻 |
| 出版者 | Frontiers Media |
| 開始ページ | 1445364 |
| ISSN | 2296-4185 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 Enomoto, Furuuchi, Ishibashi, Yamada and Oda. |
| 論文のバージョン | publisher |
| PubMed ID | 39545020 |
| DOI | 10.3389/fbioe.2024.1445364 |
| Web of Science KeyUT | 001365485200001 |
| 関連URL | isVersionOf https://doi.org/10.3389/fbioe.2024.1445364 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Hiraoka, Tomohiro| Obara, Takafumi| Matsumoto, Naomi| Tsukahara, Kohei| Hongo, Takashi| Nojima, Tsuyoshi| Hisamura, Masaki| Yumoto, Tetsuya| Nakao, Atsunori| Yorifuji, Takashi| Naito, Hiromichi| |
| キーワード | Retrospective cohort study Injury recurrence Injury prevention |
| 備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-76403-z| |
| 発行日 | 2024-10-21 |
| 出版物タイトル | Scientific Reports |
| 巻 | 14巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 24716 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 39433855 |
| DOI | 10.1038/s41598-024-76403-z |
| Web of Science KeyUT | 001339991400047 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-024-76403-z |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kanemoto, Hideka| Obata, Kyoichi| Kadoya, Koichi| Ono, Kisho| Kawai, Hotaka| Kunisada, Yuki| Yao, Mayumi| Ibaragi, Soichiro| |
| 発行日 | 2024-10-28 |
| 出版物タイトル | Case Reports in Dentistry |
| 巻 | 2024巻 |
| 出版者 | Wiley |
| 開始ページ | 8836103 |
| ISSN | 2090-6447 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 Hideka Kanemoto et al. |
| 論文のバージョン | publisher |
| PubMed ID | 39503010 |
| DOI | 10.1155/2024/8836103 |
| Web of Science KeyUT | 001352105100001 |
| 関連URL | isVersionOf https://doi.org/10.1155/2024/8836103 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Miyamoto, Satoshi| Heerspink, Hiddo J.L.| de Zeeuw, Dick| Sakamoto, Kota| Yoshida, Michihiro| Toyoda, Masao| Suzuki, Daisuke| Hatanaka, Takashi| Nakamura, Tohru| Kamei, Shinji| Murao, Satoshi| Hida, Kazuyuki| Ando, Shinichiro| Akai, Hiroaki| Takahashi, Yasushi| Kitada, Munehiro| Sugano, Hisashi| Nunoue, Tomokazu| Nakamura, Akihiko| Sasaki, Motofumi| Nakatou, Tatsuaki| Fujimoto, Kei| Kawanami, Daiji| Wada, Takashi| Miyatake, Nobuyuki| Kuramoto, Hiromi| Shikata, Kenichi| |
| キーワード | canagliflozin CANPIONE study chronic kidney disease microalbuminuria preintervention eGFR slope sodium-glucose cotransporter 2 inhibitor |
| 発行日 | 2024-11 |
| 出版物タイトル | Kidney International |
| 巻 | 106巻 |
| 号 | 5号 |
| 出版者 | Elsevier BV |
| 開始ページ | 972 |
| 終了ページ | 984 |
| ISSN | 0085-2538 |
| NCID | AA00710996 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 International Society of Nephrology. |
| 論文のバージョン | publisher |
| PubMed ID | 39216659 |
| DOI | 10.1016/j.kint.2024.08.019 |
| Web of Science KeyUT | 001343408600001 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.kint.2024.08.019 |
| JaLCDOI | 10.18926/OER/67705 |
|---|---|
| タイトル（別表記） | Why Is Intermediate Organization Necessary? |
| フルテキストURL | oer_056_2_001_016.pdf |
| 著者 | 藤井 大児| 大島 珠子| |
| 抄録 | This paper challenges a fundamental question, ‘Why is an intermediate organization necessary?’ Due to transaction costs and market failures on the one hand and the limitations of organizational control mechanisms on the other hand, many‘ intermediate organizations’ are observed in the real world. How can we tackle to explain the governance mechanism considered to be‘ intermediate?’ If we are to discuss such socioeconomic orders, this paper assumes that we should not be able to link micro-level explanations and macro-level ones concerning the third mode of governance mechanisms all at once. We need to stick to the meso-level at fi rst. The theoretical elaboration since Ouchi’s（1980） discussion of clan-type governance and cumulative empirical research on industrial agglomerations have allowed us to construct a more sophisticated theory called community capital. In effective communities, members are ‘embedded as insiders’ who serve the purpose of the community, share experiences of failures and successes, and find and deepen their common identity. This limited membership is bound by‘ mutual trust to rely on each other’ for‘ distribution of short-term risks.’ In contrast to social norms that need to be abstract enough to be widely shared, the communal norms that are concrete enough to allow the members to understand without hesitation how they should behave in localized contexts are cumulatively cultivated along socializing process. Among the norms, sense of mutual obligation to incur intermittent costs for the whole community is a crucial norm for the sustainable development of the community. However, as a practical matter, membership control, mutual trust and short-term risk allocation may serve the communities in the short run, but they do not guarantee long-term accumulation of shared capital. As a result, the limits of community capital may need to be discussed once again, especially today when market liquidity is increasing, and its failures tend to become more apparent in a variety of areas. |
| キーワード | 中間組織 内部組織の経済学 産業集積 コミュニティ・キャピタル |
| 出版物タイトル | 岡山大学経済学会雑誌 |
| 発行日 | 2024-11-25 |
| 巻 | 56巻 |
| 号 | 2号 |
| 開始ページ | 1 |
| 終了ページ | 16 |
| ISSN | 2433-4146 |
| 言語 | 日本語 |
| 著作権者 | Copyright © 2024 岡山大学経済学会 |
| 論文のバージョン | publisher |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Nishimura, Seitaro| Noma, Kazuhiro| Kawasaki, Kento| Hashimoto, Masashi| Kato, Takuya| Maeda, Naoaki| Tanabe, Shunsuke| Shirakawa, Yasuhiro| Fujiwara, Toshiyoshi| |
| キーワード | Gastro-tracheal fistula Esophageal cancer Retrosternal route Esophageal surgery |
| 備考 | The version of record of this article, first published in Surgical Case Reports, is available online at Publisher’s website: http://dx.doi.org/10.1186/s40792-024-02052-z| |
| 発行日 | 2024-11-04 |
| 出版物タイトル | Surgical Case Reports |
| 巻 | 10巻 |
| 号 | 1号 |
| 出版者 | Springer |
| 開始ページ | 252 |
| ISSN | 2198-7793 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024. |
| 論文のバージョン | publisher |
| PubMed ID | 39489816 |
| DOI | 10.1186/s40792-024-02052-z |
| Web of Science KeyUT | 001347685400001 |
| 関連URL | isVersionOf https://doi.org/10.1186/s40792-024-02052-z |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Vu, Thuy Ha| Nakamura, Keiichiro| Shigeyasu, Kunitoshi| Kashino, Chiaki| Okamoto, Kazuhiro| Kubo, Kotaro| Kamada, Yasuhiko| Masuyama, Hisashi| |
| キーワード | Apolipoprotein-B mRNA-editing complex 3B Endometriosis Apoptosis Potential therapeutic target |
| 備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-76589-2| |
| 発行日 | 2024-10-23 |
| 出版物タイトル | Scientific Reports |
| 巻 | 14巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 24968 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 39443671 |
| DOI | 10.1038/s41598-024-76589-2 |
| Web of Science KeyUT | 001341352800136 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-024-76589-2 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Nishikori, Asami| Nishimura, Midori Filiz| Tomida, Shuta| Chijimatsu, Ryota| Ueta, Himawari| Lai, You Cheng| Kawahara, Yuri| Takeda, Yudai| Ochi, Sayaka| Haratake, Tomoka| Ennishi, Daisuke| Nakamura, Naoya| Momose, Shuji| Sato, Yasuharu| |
| キーワード | idiopathic multicentric Castleman disease cytokine storm transcriptome analysis |
| 発行日 | 2024 |
| 出版物タイトル | Journal of Clinical and Experimental Hematopathology |
| 巻 | 64巻 |
| 号 | 4号 |
| 出版者 | Japanese Society for Lymphoreticular Tissue Research |
| 開始ページ | 297 |
| 終了ページ | 306 |
| ISSN | 1346-4280 |
| NCID | AA11556796 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 The Japanese Society for Lymphoreticular Tissue Research |
| 論文のバージョン | publisher |
| PubMed ID | 39462545 |
| DOI | 10.3960/jslrt.24061 |
| Web of Science KeyUT | 001344315800001 |
| 関連URL | isVersionOf https://doi.org/10.3960/jslrt.24061 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yamanaka-Kohno, Reiko| Shirakawa, Yasuhiro| Yokoi, Aya| Maeda, Naoaki| Tanabe, Shunsuke| Noma, Kazuhiro| Shimizu, Kazuyoshi| Mituhashi, Toshiharu| Nakamura, Yoshihide| Nanba, Souto| Uchida, Yurika| Maruyama, Takayuki| Morita, Manabu| Ekuni, Daisuke| |
| キーワード | Esophageal cancer Esophagectomy Gum-chewing training Tongue pressure Historical control Propensity score matching analysis |
| 備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-74090-4| |
| 発行日 | 2024-10-12 |
| 出版物タイトル | Scientific Reports |
| 巻 | 14巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 23886 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 39396079 |
| DOI | 10.1038/s41598-024-74090-4 |
| Web of Science KeyUT | 001336579100027 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-024-74090-4 |
| フルテキストURL | fulltext.pdf correction.pdf |
|---|---|
| 著者 | Obayashi, Yuka| Hirata, Shoichiro| Kono, Yoshiyasu| Abe, Makoto| Miyahara, Koji| Nakagawa, Masahiro| Ishida, Michihiro| Choda, Yasuhiro| Hamada, Kenta| Iwamuro, Masaya| Kawano, Seiji| Kawahara, Yoshiro| Otsuka, Motoyuki| |
| 備考 | The version of record of this article, first published in Drugs - Real World Outcomes, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40801-024-00460-z| |
| 発行日 | 2024-10-19 |
| 出版物タイトル | Drugs - Real World Outcomes |
| 巻 | 11巻 |
| 号 | 4号 |
| 出版者 | Springer Nature |
| 開始ページ | 557 |
| 終了ページ | 564 |
| ISSN | 2199-1154 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 39425893 |
| DOI | 10.1007/s40801-024-00460-z |
| Web of Science KeyUT | 001337505400001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s40801-024-00460-z |
| JaLCDOI | 10.18926/AMO/67667 |
|---|---|
| フルテキストURL | 78_5_423.pdf |
| 著者 | Sakamoto, Shinya| Tabuchi, Motoyasu| Yoshimatsu, Rika| Hishida, Ai| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| |
| 抄録 | Nesidioblastosis, also known as persistent hyperinsulinemic hypoglycemia, is usually observed in children and infants, although more recently adult-onset nesidioblastosis has also been described. We present a case of nesidioblastosis in a 78-year-old man that was detected by 111In-pentetreotide single photon emission computed tomography (SPECT/CT). The patient was transferred to our hospital’s emergency department in a hypoglycemic coma. Dynamic enhanced CT could detect no lesion in the pancreas, but an 111In-pentetreotide SPECT/CT scan performed after a similar episode four weeks later showed increased focal uptake at the head of the pancreas. The results of a selective arterial calcium injection test were negative. After careful consideration and discussion among colleagues, surgical intervention was selected, and a pancreaticoduodenectomy was performed. On histology, there were elevated numbers of Langerhans islets in the pancreatic head, and the islets themselves appeared enlarged. Hypertrophic β-cells comprised the majority, but α-cells, δ-cells and pancreatic polypeptide were also detected in the islets. Based on the histopathological results and repeated hyperinsulinemic hypoglycemic crises, the patient was finally diagnosed with adult-onset nesidioblastosis. He had no hypoglycemic symptoms during outpatient follow-up examination. Since 111In-pentetreotide SPECT/CT may be able to detect nesidioblastosis, clinicians should consider this relatively new-modality examination when encountering such cases. |
| キーワード | 111In-pentetreotide nesidioblastosis single-photon emission computed tomography hyperinsulinemic hypoglycemia |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 423 |
| 終了ページ | 428 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467661 |
| Web of Science KeyUT | 001343346400009 |
| JaLCDOI | 10.18926/AMO/67666 |
|---|---|
| フルテキストURL | 78_5_413.pdf |
| 著者 | Kashihara, Kenichi| Irisawa, Minoru| Takao, Wataru| |
| 抄録 | We investigated patients with migraine or migraine variants who exhibited focal cerebral hypoperfusion on arterial spin-labeled (ASL) magnetic resonance (MR) imaging along with neurological symptoms. Fourteen patients with migraine demonstrated focal cerebral hypoperfusion. Three other patients did not have a history of recurrent headaches but exhibited comparable cerebral hypoperfusion to migraine patients on ASL-MRI in addition to neurological symptoms. Patients with migraine may present with neurological symptoms associated with cortical spreading depression during, after, or even without a headache phase. Additionally, the isolated neurological symptoms may be caused by a pathophysiology identical to that of migraine but without presenting with recurrent headaches. |
| キーワード | arterial spin-labeled magnetic resonance imaging cortical spreading depression migraine complex migraine without headache vertigo |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 413 |
| 終了ページ | 421 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467660 |
| JaLCDOI | 10.18926/AMO/67665 |
|---|---|
| フルテキストURL | 78_5_407.pdf |
| 著者 | Shimoyama, Kyoko| Nakajima, Atsushi| Minari, Yoshimitsu| |
| 抄録 | Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, but they have been known to cause immune-related adverse events (irAEs) by promoting T-cell activation. Neurological irAEs are rare (1%) but have a high fatality rate (11.5%). Here we report the first case of Bickerstaff brainstem encephalitis (BBE) induced by an ICI. A woman in her 60s with metastatic breast cancer was treated with atezolizumab plus nab-paclitaxel once intravenously. Eighteen days later, she lost consciousness with ophthalmoplegia and was diagnosed with a neurological irAE. She recovered consciousness immediately with the administration of intravenous immunoglobulin (IVIG) but suffered severe permanent peripheral neuropathy. Although it is just one case, this experience shows that BBE occurring as a neurological irAE of ICI cancer treatment may be associated with more severe outcomes than conventional BBE in metastatic cancer. Creating a system for multidisciplinary treatment is essential for ICI therapy. |
| キーワード | Bickerstaff brainstem encephalitis immune checkpoint inhibitor atezolizumab neurological immune-related adverse event breast cancer |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 407 |
| 終了ページ | 412 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467659 |
| Web of Science KeyUT | 001343346400007 |
| JaLCDOI | 10.18926/AMO/67663 |
|---|---|
| フルテキストURL | 78_5_387.pdf |
| 著者 | Naoe, Shota| Tanaka, Ayumi| Kanzaki, Norie| Takenaka, Reiju| Sakoda, Akihiro| Miyaji, Takaaki| Yamaoka, Kiyonori| Kataoka, Takahiro| |
| 抄録 | Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation. |
| キーワード | radon inhalation proteomics multivariate analysis brain oxidative stress |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 387 |
| 終了ページ | 399 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467657 |
| Web of Science KeyUT | 001343346400005 |
| JaLCDOI | 10.18926/AMO/67657 |
|---|---|
| フルテキストURL | 78_5_371.pdf |
| 著者 | Gotoh, Kazuyoshi| Miyoshi, Makoto| I Putu Bayu Mayura| Tsuji, Shuma| Iio, Koji| Fukushima, Shinnosuke| Matsushita, Osamu| Hagiya, Hideharu| |
| 抄録 | Spread of carbapenemase-producing Enterobacterales (CPE) is an ongoing public health issue worldwide, including in Japan. In this study, we investigated the phenotypic and genetic characteristics of CPE isolates at Okayama University Hospital over the 5 years (2013-2018) prior to the outbreak of the 2019 coronavirus pandemic. Of 24 carbapenem-resistant Enterobacterales isolated during the study period, we identified 8 CPE isolates harboring blaIMP-1 (5 isolates) and blaIMP-6 genes (3 isolates). Bacterial species and carbapenem susceptibility patterns exhibited diversity. Minimum inhibitory concentrations (MICs) of meropenem were generally higher than those of imipenem and biapenem. Results of pulsed-field gel electrophoresis demonstrated that neither clonal nor plasmid-mediated outbreaks of blaIMP-harboring CPE isolates have developed at our hospital. One Klebsiella oxytoca isolate showed a high MIC (128 μg/mL) of meropenem, which could be explained by the high plasmid copy number. Subsequent analysis of this isolate may elucidate the intricacies of carbapenem resistance profiles among CPE isolates. Collectively, our findings underscore the necessity for ongoing genetic surveillance of CPE, complemented by tailored approaches for infection prevention and control. |
| キーワード | antimicrobial resistance carbapenemase-producing enterobacterales carbapenemase-resistant enterobacterales Silent pandemic whole genome sequence |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 371 |
| 終了ページ | 376 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467655 |
| Web of Science KeyUT | 001343346400003 |
| JaLCDOI | 10.18926/AMO/67656 |
|---|---|
| フルテキストURL | 78_5_363.pdf |
| 著者 | Takanaga, Satoe| Matsumoto, Naomi| Kadowaki, Tomoka| Takao, Soshi| Yorifuji, Takashi| |
| 抄録 | Kawasaki disease (KD) is a pediatric disease of unknown etiology that commonly affects infants in East Asia. Infants born small for gestational age (SGA) have weaker immune systems and are more susceptible to infection. Using data from a nationwide Japanese birth cohort study conducted in 2010 (n=34,579), we investigated whether SGA increases the risk of KD. SGA was defined as birth weight below the 10th percentile for gestational age. The outcome was hospitalization for KD between 6 and 30 months of age. The association between SGA and hospitalization for KD, adjusted for child and maternal factors, was examined using logistic regression. Of the 231 children hospitalized for KD, 9.5% were SGA. Further statistical analysis showed that SGA did not increase the odds ratio (OR) of hospitalization for KD (adjusted OR 1.12, 95% confidence interval 0.71-1.75). This result was not changed with stratification by early daycare attendance and preterm status. Reasons for the lack of association may include the multifactorial pathogenesis of KD; in addition, the types of infections to which SGA infants are predisposed may differ from those triggering KD. Overall, our large nationwide study found no association between SGA and KD. |
| キーワード | Kawasaki disease (KD) small for gestational age (SGA) cohort epidemiology |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 363 |
| 終了ページ | 370 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467654 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Hirata, Shoichiro| Hamada, Kenta| Iwamuro, Masaya| Mouri, Hirokazu| Miyahara, Koji| Tsuzuki, Takao| Yamauchi, Kenji| Kobayashi, Sayo| Takahashi, Sakuma| Takenaka, Ryuta| Hori, Shinichiro| Inoue, Masafumi| Toyokawa, Tatsuya| Nishimura, Mamoru| Ishiyama, Shuhei| Miyaike, Jiro| Kato, Ryo| Matsubara, Minoru| Yunoki, Naoko| Kanzaki, Hiromitsu| Kawahara, Yoshiro| Okada, Hiroyuki| Ishikawa, Hideki| Otsuka, Motoyuki| Okayama Gut Study Group| |
| キーワード | direct oral anticoagulants endoscopic submucosal dissection gastric cancer postprocedural bleeding warfarin |
| 発行日 | 2024-10-03 |
| 出版物タイトル | Journal of Gastroenterology and Hepatology |
| 巻 | 39巻 |
| 号 | 12号 |
| 出版者 | Wiley |
| 開始ページ | 2760 |
| 終了ページ | 2766 |
| ISSN | 0815-9319 |
| NCID | AA10727383 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 39363400 |
| DOI | 10.1111/jgh.16757 |
| Web of Science KeyUT | 001328472100001 |
| 関連URL | isVersionOf https://doi.org/10.1111/jgh.16757 |