検索結果 - 岡山大学学術成果リポジトリ

Clinicopathological and histological analysis of secondary malignant giant cell tumors of bone without radiotherapy

フルテキストURL	fulltext.pdf
著者	Nakata, Eiji\| Kawai, Hotaka\| Fujiwara, Tomohiro\| Kunisada, Toshiyuki\| Inoue, Hirofumi\| Futagawa, Mashu\| Katayama, Haruyoshi\| Itano, Takuto\| Ozaki, Toshifumi\|
キーワード	giant cell tumor of bone malignant transformation p53 denosumab molecular targeted therapy
発行日	2022-07-19
出版物タイトル	Oncology Letters
巻	24巻
号	3号
出版者	Spandidos Publications
開始ページ	319
ISSN	1792-1074
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Nakata et al.
論文のバージョン	publisher
PubMed ID	35949597
DOI	10.3892/ol.2022.13439
Web of Science KeyUT	000840512400001
関連URL	isVersionOf https://doi.org/10.3892/ol.2022.13439

Incremental prognostic value of non-alcoholic fatty liver disease over coronary computed tomography angiography findings in patients with suspected coronary artery disease

フルテキストURL	fulltext.pdf
著者	Ichikawa, Keishi\| Miyoshi, Toru\| Osawa, Kazuhiro\| Miki, Takashi\| Toda, Hironobu\| Ejiri, Kentaro\| Yoshida, Masashi\| Nakamura, Kazufumi\| Morita, Hiroshi\| Ito, Hiroshi\|
キーワード	Coronary artery disease Computed tomography angiography Atherosclerotic plaque Risk assessment Hepatic steatosis
発行日	2021-07-19
出版物タイトル	European Journal of Preventive Cardiology
巻	28巻
号	18号
出版者	Oxford University Press (OUP)
開始ページ	2059
終了ページ	2066
ISSN	2047-4873
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2021.
論文のバージョン	publisher
PubMed ID	34279027
DOI	10.1093/eurjpc/zwab120
Web of Science KeyUT	000753584300031
関連URL	isVersionOf https://doi.org/10.1093/eurjpc/zwab120

Comparison of Bilateral and Trisegment Drainage in Patients with High-Grade Hilar Malignant Biliary Obstruction: A Multicenter Retrospective Study

フルテキストURL	fulltext.pdf
著者	Matsumoto, Kazuyuki\| Kato, Hironari\| Morimoto, Kosaku\| Miyamoto, Kazuya\| Saragai, Yosuke\| Kawamoto, Hirofumi\| Okada, Hiroyuki\|
キーワード	Bile duct obstruction Neoplasms Endoscopic biliary drainage Bilateral drainage Self-expandable metallic stents
発行日	2022-07-19
出版物タイトル	Gut and Liver
巻	17巻
号	1号
出版者	The Editorial Office of Gut and Liver
開始ページ	170
終了ページ	178
ISSN	1976-2283
NCID	AA12329814
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Gut and Liver.
論文のバージョン	publisher
PubMed ID	35851039
DOI	10.5009/gnl220012
Web of Science KeyUT	000830704600001
関連URL	isVersionOf https://doi.org/10.5009/gnl220012

Detailed Anatomy of Bridging Veins Around the Foramen Magnum: a Multicenter Study Using Three-dimensional Angiography

フルテキストURL	fulltext20230912-02.pdf
著者	Hiramatsu, Masafumi\| Ozaki, Tomohiko\| Tanoue, Shuichi\| Mizutani, Katsuhiro\| Nakamura, Hajime\| Tokuyama, Kohei\| Sakata, Hiroyuki\| Matsumaru, Yuji\| Nakahara, Ichiro\| Niimi, Yasunari\| Fujinaka, Toshiyuki\| Kiyosue, Hiro\|
キーワード	Bridging vein Foramen magnum Cone-beam CT Venous phase three-dimensional rotational angiography Slab maximum intensity projection Dural arteriovenous fistula
備考	The version of record of this article, first published in Clinical Neuroradiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00062-023-01327-6\|
発行日	2023-08-08
出版物タイトル	Clinical Neuroradiology
巻	34巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	67
終了ページ	74
ISSN	1869-1439
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37552244
DOI	10.1007/s00062-023-01327-6
Web of Science KeyUT	001044319100001
関連URL	isVersionOf https://doi.org/10.1007/s00062-023-01327-6

Randomized phase II study of daily versus alternate-day administrations of S-1 for the elderly patients with completely resected pathological stage IA (tumor diameter > 2 cm)-IIIA of non-small cell lung cancer: Setouchi Lung Cancer Group Study 1201

フルテキストURL	fulltext.pdf
著者	Yamamoto, Hiromasa\| Soh, Junichi\| Okumura, Norihito\| Suzuki, Hiroyuki\| Nakata, Masao\| Fujiwara, Toshiya\| Gemba, Kenichi\| Sano, Isao\| Fujinaga, Takuji\| Kataoka, Masafumi\| Terazaki, Yasuhiro\| Fujimoto, Nobukazu\| Kataoka, Kazuhiko\| Kosaka, Shinji\| Yamashita, Motohiro\| Inokawa, Hidetoshi\| Inoue, Masaaki\| Nakamura, Hiroshige\| Yamashita, Yoshinori\| Hotta, Katsuyuki\| Yoshioka, Hiroshige\| Morita, Satoshi\| Matsuo, Keitaro\| Sakamoto, Junichi\| Date, Hiroshi\| Toyooka, Shinichi\|
発行日	2023-05-19
出版物タイトル	PLoS ONE
巻	18巻
号	5号
出版者	Public Library of Science
開始ページ	e0285273
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 Yamamoto et al.
論文のバージョン	publisher
PubMed ID	37205678
DOI	10.1371/journal.pone.0285273
Web of Science KeyUT	001050599900034
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0285273

令和４年度岡山医学会賞　総合研究奨励賞（結城賞）

タイトル（別表記）	The 2022 Incentive Award of the Okayama Medical Association in General Medical Science (2022 Yuuki Prize)
フルテキストURL	135_55.pdf
著者	萩谷英大\|
出版物タイトル	岡山医学会雑誌
発行日	2023-08-01
巻	135巻
号	2号
開始ページ	55
終了ページ	57
ISSN	0030-1558
関連URL	isVersionOf https://doi.org/10.4044/joma.135.55
言語	日本語
著作権者	Copyright (c) 2023 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.135.55

Search for Astrophysical Electron Antineutrinos in Super-Kamiokande with 0.01% Gadolinium-loaded Water

フルテキストURL	fulltext.pdf
著者	Harada, M.\|
備考	システム処理の都合により筆頭著者のみ著者登録、その他の著者については以下の通り。 K. Abe2,3, C. Bronner2 , Y. Hayato2,3 , K. Hiraide2,3 , K. Hosokawa2 , K. Ieki2,3 , M. Ikeda2,3 , J. Kameda2,3, Y. Kanemura2, R. Kaneshima2, Y. Kashiwagi2, Y. Kataoka2,3 , S. Miki2, S. Mine2,4, M. Miura2,3, S. Moriyama2,3 , Y. Nakano2 , M. Nakahata2,3 , S. Nakayama2,3 , Y. Noguchi2 , K. Okamoto2, K. Sato2, H. Sekiya2,3 , H. Shiba2, K. Shimizu2, M. Shiozawa2,3 , Y. Sonoda2, Y. Suzuki2, A. Takeda2,3, Y. Takemoto2,3 , A. Takenaka2, H. Tanaka2,3, S. Watanabe2, T. Yano2 , S. Han5, T. Kajita3,5,6, K. Okumura3,5 , T. Tashiro5 , T. Tomiya5, X. Wang5, S. Yoshida5, G. D. Megias7, P. Fernandez8 , L. Labarga8 , N. Ospina8 , B. Zaldivar8, B. W. Pointon9,10, E. Kearns3,11, J. L. Raaf11, L. Wan11 , T. Wester11 , J. Bian4, N. J. Griskevich4 , S. Locke4, M. B. Smy3,4, H. W. Sobel3,4 , V. Takhistov4,12, A. Yankelevich4 , J. Hill13, S. H. Lee14, D. H. Moon14, R. G. Park14, B. Bodur15 , K. Scholberg3,15 , C. W. Walter3,15 , A. Beauchêne16, O. Drapier16, A. Giampaolo16, Th. A. Mueller16 , A. D. Santos16, P. Paganini16 , B. Quilain16, T. Ishizuka17, T. Nakamura18, J. S. Jang19, J. G. Learned20, K. Choi21, N. Iovine21 , S. Cao22, L. H. V. Anthony23, D. Martin23, M. Scott23 , A. A. Sztuc23, Y. Uchida23, V. Berardi24 , M. G. Catanesi24, E. Radicioni24, N. F. Calabria25 , A. Langella25 , L. N. Machado25 , G. De Rosa25, G. Collazuol26 , F. Iacob26 , M. Lamoureux26, M. Mattiazzi26 , L. Ludovici27, M. Gonin6, G. Pronost6 , C. Fujisawa28, Y. Maekawa28, Y. Nishimura28 , R. Okazaki28, R. Akutsu12, M. Friend12, T. Hasegawa12 , T. Ishida12, T. Kobayashi12, M. Jakkapu12, T. Matsubara12 , T. Nakadaira12, K. Nakamura3,12, Y. Oyama12 , K. Sakashita12, T. Sekiguchi12, T. Tsukamoto12, N. Bhuiyan29, G. T. Burton29, F. Di Lodovico29 , J. Gao29, A. Goldsack29, T. Katori29 , J. Migenda29 , Z. Xie29, S. Zsoldos3,29 , Y. Kotsar30, H. Ozaki30, A. T. Suzuki30, Y. Takagi30, Y. Takeuchi3,30 , J. Feng31, L. Feng31, J. R. Hu31 , Z. Hu31 , T. Kikawa31, M. Mori31, T. Nakaya3,31 , R. A. Wendell3,31 , K. Yasutome31, S. J. Jenkins32 , N. McCauley32 , P. Mehta32, A. Tarrant32 , Y. Fukuda33 , Y. Itow34,35 , H. Menjo34 , K. Ninomiya34, J. Lagoda36, S. M. Lakshmi36, M. Mandal36, P. Mijakowski36, Y. S. Prabhu36, J. Zalipska36, M. Jia37, J. Jiang37, C. K. Jung37, M. J. Wilking37, C. Yanagisawa37,56 , Y. Hino1 , H. Ishino1, H. Kitagawa1, Y. Koshio1,3 , F. Nakanishi1 , S. Sakai1 , T. Tada1, T. Tano1, G. Barr38, D. Barrow38 , L. Cook3,38, S. Samani38, D. Wark38,39, A. Holin40, F. Nova41 , B. S. Yang40 , J. Y. Yang40 , J. Yoo40 , J. E. P. Fannon42, L. Kneale42 , M. Malek42, J. M. McElwee42, M. D. Thiesse42 , L. F. Thompson42, S. T. Wilson42, H. Okazawa43, S. B. Kim44, E. Kwon44 , J. W. Seo44 , I. Yu44 , A. K. Ichikawa45, K. D. Nakamura45 , S. Tairafune45 , K. Nishijima46 , K. Nakagiri47, Y. Nakajima3,47 , S. Shima47, N. Taniuchi47, E. Watanabe47, M. Yokoyama3,47 , P. de Perio3 , K. Martens3, K. M. Tsui3, M. R. Vagins3,4 , J. Xia3, M. Kuze48 , S. Izumiyama48 , R. Matsumoto48 , M. Ishitsuka49, H. Ito49 , T. Kinoshita49, R. Matsumoto49, Y. Ommura49, N. Shigeta49, M. Shinoki49 , T. Suganuma49, K. Yamauchi49, J. F. Martin50, H. A. Tanaka50, T. Towstego50, R. Gaur10, V. Gousy-Leblanc10,57, M. Hartz10, A. Konaka10, X. Li10, N. W. Prouse10,51 , S. Chen51, B. D. Xu51 , B. Zhang51, M. Posiadala-Zezula52 , S. B. Boyd53, R. Edwards53, D. Hadley53, M. Nicholson53, M. O’Flaherty53, B. Richards53, A. Ali10,54, B. Jamieson54, Ll. Marti55 , A. Minamino55 , G. Pintaudi55, S. Sano55, S. Suzuki55, K. Wada55, and The Super-Kamiokande Collaboration 1 Department of Physics, Okayama University 2 Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo 3 Kavli Institute for the Physics and Mathematics of the Universe (WPI), The University of Tokyo Institutes for Advanced Study, University of Tokyo 4 Department of Physics and Astronomy, University of California 5 Research Center for Cosmic Neutrinos, Institute for Cosmic Ray Research, University of Tokyo 6 ILANCE, CNRS - University of Tokyo International Research Laboratory 7 Institute for Cosmic Ray Research, University of Tokyo 8 Department of Theoretical Physics, University Autonoma Madrid 9 Department of Physics, British Columbia Institute of Technology 10 TRIUMF 11 Department of Physics, Boston University 12 High Energy Accelerator Research Organization (KEK) 13 Department of Physics, California State University 14 Institute for Universe and Elementary Particles, Chonnam National University 15 Department of Physics, Duke University 16 Ecole Polytechnique, IN2P3-CNRS, Laboratoire Leprince-Ringuet 17 Junior College, Fukuoka Institute of Technology 18 Department of Physics, Gifu University 19 GIST College, Gwangju Institute of Science and Technology 20 Department of Physics and Astronomy, University of Hawaii 21 Institute for Basic Science (IBS) 22 Institute For Interdisciplinary Research in Science and Education, ICISE 23 Department of Physics, Imperial College London 24 Dipartimento Interuniversitario di Fisica, INFN Sezione di Bari and Università e Politecnico di Bari 25 Dipartimento di Fisica, INFN Sezione di Napoli and Università di Napoli 26 Dipartimento di Fisica, INFN Sezione di Padova and Università di Padova 27 INFN Sezione di Roma and Università di Roma "La Sapienza," 28 Department of Physics, Keio University 29 Department of Physics, King's College London 30 Department of Physics, Kobe University, Kobe 31 Department of Physics, Kyoto University, Kyoto 32 Department of Physics, University of Liverpool 33 Department of Physics, Miyagi University of Education 34 Institute for Space-Earth Environmental Research, Nagoya University 35 Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University 36 National Centre For Nuclear Research 37 Department of Physics and Astronomy, State University of New York at Stony Brook 38 Department of Physics, Oxford University 39 STFC, Rutherford Appleton Laboratory, Harwell Oxford, and Daresbury Laboratory 40 Department of Physics, Seoul National University 41 Rutherford Appleton Laboratory 42 Department of Physics and Astronomy, University of Sheffield 43 Department of Informatics in Social Welfare, Shizuoka University of Welfare 44 Department of Physics, Sungkyunkwan University 45 Department of Physics, Faculty of Science, Tohoku University 46 Department of Physics, Tokai University 47 Department of Physics, University of Tokyo 48 Department of Physics, Tokyo Institute of Technology 49 Department of Physics, Faculty of Science and Technology, Tokyo University of Science 50 Department of Physics, University of Toronto 51 Department of Engineering Physics, Tsinghua University 52 Faculty of Physics, University of Warsaw 53 Department of Physics, University of Warwick 54 Department of Physics, University of Winnipeg 55 Department of Physics, Yokohama National University\|
発行日	2023-07-07
出版物タイトル	Astrophysical Journal Letters
巻	951巻
号	2号
出版者	IOP Publishing Ltd
開始ページ	L27
ISSN	2041-8205
NCID	AA00553264
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023. The Author(s).
論文のバージョン	publisher
DOI	10.3847/2041-8213/acdc9e
Web of Science KeyUT	001026263300001
関連URL	isVersionOf https://doi.org/10.3847/2041-8213/acdc9e

A Case of Acute Zonal Occult Outer Retinopathy in which Oct en Face Imaging Was Useful for Diagnosis and Follow-up

JaLCDOI	10.18926/AMO/65756
フルテキストURL	77_4_433.pdf
著者	Ono, Ryuki\| Shiode, Yusuke\| Kimura, Shuhei\| Hosokawa, Mio\| Matoba, Ryo\| Kanzaki, Yuki\| Kindo, Hiroya\| Morita, Tetsuro\| Morizane, Yuki\|
抄録	A 23-year-old woman presented with a 1-month history of visual abnormalities in her right eye. A visual field test revealed temporal abnormalities in the right eye. Optical coherence tomography revealed an indistinct ellipsoid zone (EZ) on the B-scan image and hyporeflective areas in the EZ layer on the en face image in the right eye. We diagnosed the patient with acute zonal occult outer retinopathy. Visual field tests and B-scan images improved to almost normal at 6 months, but hyporeflective areas remained on the en face images. Thus, en face images may be more sensitive at detecting abnormalities in the outer retina than other modalities.
キーワード	acute zonal occult outer retinopathy optical coherence tomography en face image ellipsoid zone
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	433
終了ページ	437
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635145
Web of Science KeyUT	001088434900001

An Unusual Presentation of Chest Pain and Laryngeal Discomfort in a Pregnant Woman: A Case Report and Literature Review

JaLCDOI	10.18926/AMO/65755
フルテキストURL	77_4_429.pdf
著者	Sasanami, Misa\| Iida, Atsuyoshi\| Iwamuro, Masaya\| Hirai, Ryousuke\| Obara, Takashi\| Tsukahara, Kohei\| Yumoto, Tetsuya\| Naito, Hiromichi\| Nakao, Atsunori\|
抄録	Intramural esophageal dissection (IED), characterized by bleeding into the submucosal space, leads to mucosal separation and dissection. The most prevalent symptoms are sudden chest or retrosternal pain, hematemesis, and dysphagia. Therefore, acute coronary syndrome and aortic dissection are among its most notable differential diagnoses. A 31-year-old pregnant woman presented with acute chest pain, laryngeal discomfort, and hematemesis. Emergency esophagogastroscopy revealed longitudinal mucosal dissection (upper esophagus to esophagogastric junction). The patient was successfully treated by avoiding the ingestion of solid foods. Clinicians should consider a diagnosis of IED for pregnant patients with acute chest pain, especially if hematemesis is present.
キーワード	chest pain dysphagia esophageal dissection hematemesis
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	429
終了ページ	431
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635144
Web of Science KeyUT	001163659800012

Immunohistochemical Expression of Placental Vitamin D Receptors in Pregnancies Complicated by Early and Late-Onset Preeclampsia

JaLCDOI	10.18926/AMO/65752
フルテキストURL	77_4_415.pdf
著者	Jelcic, Dzenis\| Puzovic, Velibor\| Benzon, Benjamin\| Palada, Ivan\| Jerković, Jelena\| Vulic, Marko\|
抄録	The aim of our study was to determine whether the immunohistochemical expression of placental vitamin D receptors is altered in pregnancies complicated by preeclampsia. Vitamin D receptor expression was immunohistochemically analysed in the placentas of three groups: a control group, and early- and late-onset preeclampsia groups. Total immunohistochemical intensity staining of placentas showed that the control group had a median vitamin D receptor (VDR) expression significantly higher than the placentas of mothers with early- and late-onset preeclampsia. There was no difference among the three groups in a semiquantitative analysis of VDR staining of the stroma only. Vitamin D receptors showed lower median expression in preeclampsia-affected pregnancies, especially early-onset preeclampsia. Therefore, Vitamin D receptor expression may be an important marker for normal placentation and preeclampsia onset.
キーワード	vitamin D receptor immunohistochemistry early and late-onset preeclampsia
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	415
終了ページ	422
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635142
Web of Science KeyUT	001163659800006

Association of Tumor Necrosis Factor-Alpha with Psychopathology in Patients with Schizophrenia

JaLCDOI	10.18926/AMO/65750
フルテキストURL	77_4_395.pdf
著者	Pavlovic, Marko\| Babic, Dragan\| Rastovic, Pejana\| Arapovic, Jurica\| Martinac, Marko\| Jakovac, Sanja\| Barbaric, Romana\|
抄録	We investigated the relationship between serum tumor necrosis factor-alpha (TNF-α) levels and psychopathological symptoms, clinical and socio-demographic characteristics and antipsychotic therapy in individuals with schizophrenia. TNF-α levels were measured in 90 patients with schizophrenia and 90 healthy controls matched by age, gender, smoking status, and body mass index. The Positive and Negative Syndrome Scale (PANSS) was used to assess the severity of psychopathology in patients. No significant differences in TNF-α levels were detected between the patients and controls (p=0.736). TNF-α levels were not correlated with total, positive, negative, general, or composite PANSS scores (all p>0.05). A significant negative correlation was observed between TNF-α levels and the PANSS cognitive factor (ρ=−0.222, p=0.035). A hierarchical regression analysis identified the cognitive factor as a significant predictor of the TNF-α level (beta=−0.258, t=−2.257, p=0.027). There were no significant differences in TNF-α levels among patients treated with different types of antipsychotics (p=0.596). TNF-α levels correlated positively with the age of onset (ρ=0.233, p=0.027) and negatively with illness duration (ρ=−0.247, p=0.019) and antipsychotic treatment duration (ρ=−0.256, p=0.015). These results indicate that TNF-α may be involved in cognitive impairment in schizophrenia, and would be a potential clinical-state marker in schizophrenia.
キーワード	tumor necrosis factor-alpha schizophrenia psychopathology immune system
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	395
終了ページ	405
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635140
Web of Science KeyUT	001163659800010

Association between Radon Hot Spring Bathing and Health Conditions: A Cross-Sectional Study in Misasa, Japan

JaLCDOI	10.18926/AMO/65749
フルテキストURL	77_4_387.pdf
著者	Kataoka, Takahiro\| Habu, Hiroshi\| Tanaka, Ayumi\| Naoe, Shota\| Murakami, Kaito\| Fujimoto, Yuki\| Yukimine, Ryohei\| Takao, Soshi\| Mitsunobu, Fumihiro\| Yorifuji, Takashi\| Yamaoka, Kiyonori\|
抄録	No epidemiological studies have examined the health effects of daily bathing in radon hot springs. In this cross-sectional study, we investigated the associations between radon hot spring bathing and health conditions. The target population was 5,250 adults ≥ 20 years old in the town of Misasa, Japan. We collected information about the participants’ bathing habits and alleviation of a variety of disease symptoms, and their self-rated health (SRH). Unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CI) were calculated. In both the adjusted and unadjusted models of hypertension, significant associations between the > 1×/week hot spring bathing and the alleviation of hypertension symptoms were observed compared to the group whose hot spring bathing was <1×/week: adjusted model, OR 5.40 (95%CI: 1.98-14.74); unadjusted model, 3.67 (1.50-8.99) and for gastroenteritis: adjusted model, 9.18 (1.15-72.96); unadjusted model, 7.62 (1.59-36.49). Compared to the no-bathing group, higher SRH was significantly associated with both bathing < 1×/week: unadjusted model, 2.27 (1.53-3.37) and > 1×/week: adjusted model, 1.91 (1.15-3.19). These findings suggest that bathing in radon hot springs is associated with higher SRH and the alleviation of hypertension and gastroenteritis.
キーワード	radon hot spring bathing habit self-rated health cross-section study
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	387
終了ページ	394
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635139
Web of Science KeyUT	001163659800003

Disease Progression-Related Markers for Aged Non-Alcoholic Fatty Liver Disease Patients

JaLCDOI	10.18926/AMO/65748
フルテキストURL	77_4_377.pdf
著者	Morimoto, Kosaku\| Takeuchi, Yasuto\| Takaki, Akinobu\| Wada, Nozomu\| Oyama, Atsushi\| Adachi, Takuya\| Onishi, Hideki\| Shiraha, Hidenori\| Okada, Hiroyuki\|
抄録	Liver fibrosis is an important phenomenon in non-alcoholic fatty liver disease (NAFLD) progression. Standard markers reflecting liver fibrosis, including the FIB-4 index, increase with age. This study aimed to identify fibrosis progression-related markers that are diagnostically beneficial even in aged individuals. Serum levels of pro- and anti-inflammatory cytokines were measured by multiple enzyme-linked immunosorbent assay. Two standard NAFLD or fibrosis progression-related markers — the FIB-4 index and APRI score — were analyzed along with cytokine levels to define the best approach to discriminate advanced fibrosis. Ninety-eight NAFLD patients were enrolled: 59 and 39 patients with fibrosis stages 1-2 and 3-4 respectively. In addition to the FIB-4 index and APRI score, the following factors showed significant differences between stages 1-2 and stages 3-4 in a multivariate analysis: platelet counts, IP-10, and RANTES. The fibrosis stage, FIB-4, APRI, PDGF-BB, and RANTES were related to the prognosis. In aged patients, IP-10, GM-CSF, and RANTES differed between stages 1-2 and stages 3-4. FIB-4 and APRI were beneficial for their correlation with fibrosis. However, to stratify either young or elderly advanced fibrosis patients, and to identify patients likely to have a bad outcome, RANTES was the best marker.
キーワード	NAFLD NASH liver fibrosis chemokine FIB-4
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	377
終了ページ	385
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635138
Web of Science KeyUT	001163659800009

GATA4 rs61277615, rs73203482, and rs35813172 in Newborns with Transposition of the Great Arteries

JaLCDOI	10.18926/AMO/65745
フルテキストURL	77_4_365.pdf
著者	Moldovan, Elena\| Bănescu, Claudia\| Cucerea, Manuela\| Moldovan, Valeriu\| Gozar, Liliana\| Pușcașiu, Lucian\|
抄録	Congenital heart disease is the most common malformative pathology in newborns, with a worldwide incidence at 0.4-5%. We investigated the possible relationship between variations in nucleotide sequences and specific cardiac malformations in the GATA-binding factor 4 (GATA4) exon 1 region by using Sanger sequencing. Forty-four newborns from a third-level neonatal intensive care unit who were diagnosed with nonsyndromic, ductal-dependent congenital heart disease (i.e., transposition of the great arteries or ductal-dependent coarctation of the aorta) were enrolled. Their DNA was extracted using commercial methods and tested using the multiplex ligation-dependent probe amplification (MLPA) technique. The Sanger sequencing for GATA4 exon 1 in the newborns’ DNA identified rs61277615, rs73203482, and rs35813172 variants not reported in the ClinVar archive of human variations in newborns previously diagnosed with transposition of the great arteries (n=5) and coarctation of the aorta (n=1). The identification of these novel variants in newborns with transposition of the great arteries or ductal-dependent coarctation of the aorta may be the first step in determining the variants’ contribution to the occurrence of congenital heart disease. However, these results may be inconclusive, since the observed variants within GATA4 gene were not previously reported.
キーワード	transposition of the great arteries ductal-dependent coarctation of the aorta GATA4 MLPA Sanger sequencing
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	365
終了ページ	370
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635136
Web of Science KeyUT	001163659800008

Effectiveness of deep learning classifiers in histopathological diagnosis of oral squamous cell carcinoma by pathologists

フルテキストURL	fulltext.pdf
著者	Sukegawa, Shintaro\| Ono, Sawako\| Tanaka, Futa\| Inoue, Yuta\| Hara, Takeshi\| Yoshii, Kazumasa\| Nakano, Keisuke\| Takabatake, Kiyofumi\| Kawai, Hotaka\| Katsumitsu, Shimada\| Nakai, Fumi\| Nakai, Yasuhiro\| Miyazaki, Ryo\| Murakami, Satoshi\| Nagatsuka, Hitoshi\| Miyake, Minoru\|
備考	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-38343-y\|
発行日	2023-07-19
出版物タイトル	Scientific Reports
巻	13巻
号	1号
出版者	Nature Portfolio
開始ページ	11676
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37468501
DOI	10.1038/s41598-023-38343-y
Web of Science KeyUT	001033545700013
関連URL	isVersionOf https://doi.org/10.1038/s41598-023-38343-y

Changes in TRPV1 Receptor, CGRP, and BDNF Expression in Rat Dorsal Root Ganglion with Resiniferatoxin-Induced Neuropathic Pain: Modulation by Pulsed Radiofrequency Applied to the Sciatic Nerve

JaLCDOI	10.18926/AMO/65741
フルテキストURL	77_4_359.pdf
著者	Koshida, Tomohiro\| Maruta, Toyoaki\| Tanaka, Nobuhiko\| Hidaka, Kotaro\| Kurogi, Mio\| Nemoto, Takayuki\| Yanagita, Toshihiko\| Takeya, Ryu\| Tsuneyoshi, Isao\|
抄録	Pulsed radiofrequency (PRF) is a safe method of treating neuropathic pain by generating intermittent electric fields at the needle tip. Resiniferatoxin (RTX) is an ultrapotent agonist of transient receptor potential vanilloid subtype-1 (TRPV1) receptors. We investigated the mechanism of PRF using a rat model of RTX-induced neuropathic pain. After administering RTX intraperitoneally, PRF was applied to the right sciatic nerve. We observed the changes in TRPV1, calcitonin gene-related peptide (CGRP), and brain-derived neurotrophic factor (BDNF) in the dorsal root ganglia by western blotting. Expressions of TRPV1 and CGRP were significantly lower in the contralateral (RTX-treated, PRF-untreated) tissue than in control rats (p<0.0001 and p<0.0001, respectively) and the ipsilateral tissues (p<0.0001 and p<0.0001, respectively). BDNF levels were significantly higher in the contralateral tissues than in the control rats (p<0.0001) and the ipsilateral tissues (p<0.0001). These results suggest that, while TRPV1 and CGRP are decreased by RTX-induced neuronal damage, increased BDNF levels result in pain development. PRF may promote recovery from neuronal damage with concomitant restoration of TRPV1 and CGRP, and exert its analgesic effect by reversing BDNF increase. Further research is required to understand the role of TRPV1 and CGRP restoration in improving mechanical allodynia.
キーワード	pulsed radiofrequency resiniferatoxin transient receptor potential vanilloid subtype-1 (TRPV1) calcitonin gene-related peptide (CGRP) brain-derived neurotrophic factor (BDNF)
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	359
終了ページ	364
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635135
Web of Science KeyUT	001163659800011

Neuropeptidergic control circuits in the spinal cord for male sexual behaviour: Oxytocin–gastrin‐releasing peptide systems

フルテキストURL	fulltext20230817-02.pdf
著者	Oti, Takumi\| Sakamoto, Hirotaka\|
キーワード	gastrin-releasing peptide male sexual function non-synaptic volume transmission oxytocin spinal cord
備考	This is the peer reviewed version of the following article: [Oti T, Sakamoto H. Neuropeptidergic control circuits in the spinal cord for male sexual behaviour: Oxytocin–gastrin-releasing peptide systems. J Neuroendocrinol. 2023; 35(9):e13324. doi:10.1111/jne.13324], which has been published in final form at [https://doi.org/10.1111/jne.13324]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\| This fulltext file will be available in Jul. 2024.\|
発行日	2023-07-16
出版物タイトル	Journal of Neuroendocrinology
巻	35巻
号	9号
出版者	Wiley
開始ページ	e13324
ISSN	0953-8194
NCID	AA10755083
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 British Society for Neuroendocrinology.
論文のバージョン	author
PubMed ID	37515539
DOI	10.1111/jne.13324
Web of Science KeyUT	001036736100001
関連URL	isVersionOf https://doi.org/10.1111/jne.13324

Outcome of unlinked total elbow arthroplasty for rheumatoid arthritis in patients younger than 50 years old

フルテキストURL	fulltext20230817-03.pdf
著者	Nishida, Keiichiro\| Nasu, Yoshihisa\| Hashizume, Kenzo\| Okita, Shunji\| Nakahara, Ryuichi\| Saito, Taichi\| Ozaki, Toshifumi\| Inoue, Hajime\|
キーワード	Total elbow arthroplasty Rheumatoid arthritis Unlinked elbow Less than fifty years old
発行日	2023-01-13
出版物タイトル	Bone & Joint Open
巻	4巻
号	1号
出版者	British Editorial Society of Bone & Joint Surgery
開始ページ	19
終了ページ	26
ISSN	2633-1462
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 Author(s) et al.
論文のバージョン	publisher
PubMed ID	36636881
DOI	10.1302/2633-1462.41.bjo-2022-0151.r1
Web of Science KeyUT	001042052200001
関連URL	isVersionOf https://doi.org/10.1302/2633-1462.41.BJO-2022-0151.R1

Task shifting of medical office works: A preliminary questionnaire survey for generalists

フルテキストURL	fulltext.pdf
著者	Otsuka, Yuki\| Hagiya, Hideharu\| Sunada, Naruhiko\| Otsuka, Fumio\|
キーワード	burnout clerical work medical assistant overwork task shift
発行日	2023-07-25
出版物タイトル	Journal of General and Family Medicine
巻	24巻
号	5号
出版者	Wiley
開始ページ	317
終了ページ	319
ISSN	2189-7948
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 The Authors.
論文のバージョン	publisher
DOI	10.1002/jgf2.641
Web of Science KeyUT	001035827200001
関連URL	isVersionOf https://doi.org/10.1002/jgf2.641

Update in Molecular Aspects and Diagnosis of Autoimmune Gastritis

フルテキストURL	fulltext.pdf
著者	Iwamuro, Masaya\| Tanaka, Takehiro\| Otsuka, Motoyuki\|
キーワード	autoimmune gastritis esophagogastroduodenoscopy genetic predisposition lymphocyte oxidative stress
発行日	2023-06-21
出版物タイトル	Current Issues in Molecular Biology
巻	45巻
号	7号
出版者	MDPI
開始ページ	5263
終了ページ	5275
ISSN	1467-3037
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
PubMed ID	37504250
DOI	10.3390/cimb45070334
Web of Science KeyUT	001035130200001
関連URL	isVersionOf https://doi.org/10.3390/cimb45070334