| ID | 16930 |
| Eprint ID | 16930
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| フルテキストURL | |
| タイトル（別表記） | Studies on IgG-rheumatoid factor in systemic lupus erythematosus -Using the erythrocyte agglutination test-Part 1. Experimental studies
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| 著者 |
三橋 康彦
岡山大学医学部第三内科学教室
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| 抄録 | It has been difficult to detect IgG-rheumatoid factor (IgG-RF) by hemagglutination procedures. This difficulty was thought to be due to the size of IgG-RF being too small to break Z-potential on the red blood cell surface. Therefore, a new method for detection of IgG-RF in sera was devised using sheep red blood cells sensitized with rabbit gammaglobulin, and antihuman IgG antibody. Fundamental experiments were performed. The treatment of a few kinds of 19S-IgM hemagglutinins, i.e., heterophile antibody, anti-B antibody, cold agglutinin and IgMRF with 2-ME reduced hemagglutination activity. Furthermore, the addition of anti-IgM antibody restored that activity. These observations suggest that IgG-RF alone does not agglutinate sensitized sheep red blood cells, but that it might agglutinate them in the presence of antiIgG antibody.
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| キーワード | 全身性エリテマトーデス
IgG-リウマチ因子
抗グロブリン試験
Z-potential
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| 発行日 | 1979-06-30
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| 出版物タイトル |
岡山医学会雑誌
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| 出版物タイトル（別表記） | Journal of Okayama Medical Association
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| 巻 | 91巻
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| 号 | 5-6号
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| 出版者 | 岡山医学会
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| 出版者（別表記） | Okayama Medical Association
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| 開始ページ | 787
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| 終了ページ | 793
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| ISSN | 0030-1558
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| NCID | AN00032489
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| 資料タイプ |
学術雑誌論文
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| オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/91/5-6/91_5-6_787/_article/-char/ja/
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| 関連URL | http://www.okayama-u.ac.jp/user/oma/index.html
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| 言語 |
日本語
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| 著作権者 | 岡山医学会
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| 論文のバージョン | publisher
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| 査読 |
有り
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| Eprints Journal Name | joma
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