検索結果 28560 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Hayashi, Tatsuya| Okazaki, Mikio| Mitsuhashi, Toshiharu| Yamamoto, Hidetaka| Habu, Tomohiro| Shien, Kazuhiko| Suzawa, Ken| Yamamoto, Hiromasa| Otsuka, Tomoaki| Watanabe, Mototsugu| Kurosaki, Takeshi| Yamada, Eiji| Matsuda, Eisuke| Hayashi, Tatsurou| Fujiwara, Toshiya| Hayama, Makio| Tao, Hiroyuki| Yamane, Masaomi| Inokawa, Hidetoshi| Hirami, Yuji| Washio, Kazuhiro| Misao, Takahiko| Yamashita, Motohiro| Sano, Yoshifumi| Nakata, Masao| Kawamata, Osamu| Toyooka, Shinichi| |
| キーワード | partial thymectomy real-world data analysis retrospective comparative cohort study thymic carcinoma thymic epithelial tumors total thymectomy |
| 発行日 | 2025-10-10 |
| 出版物タイトル | International Journal of Surgery |
| 巻 | 112巻 |
| 号 | 2号 |
| 出版者 | Ovid Technologies (Wolters Kluwer Health) |
| 開始ページ | 2301 |
| 終了ページ | 2310 |
| ISSN | 1743-9159 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2025 The Author(s). Published by Wolters Kluwer Health, Inc. |
| 論文のバージョン | publisher |
| PubMed ID | 41085661 |
| DOI | 10.1097/js9.0000000000003600 |
| 関連URL | isVersionOf https://doi.org/10.1097/js9.0000000000003600 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Imano, Natsumi| Nishida, Mikako| Tokumasu, Miho| Zhao, Weiyang| Yamashita, Nahoko| Udono, Heiichiro| |
| キーワード | ascochlorin derivative CD8 positive T lymphocytes cell survival IFN-γ interleukin-9 Tc9 tumour immunity |
| 発行日 | 2026-02-19 |
| 出版物タイトル | British Journal of Pharmacology |
| 出版者 | Wiley |
| ISSN | 0007-1188 |
| NCID | AA00574810 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2026 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 41715914 |
| DOI | 10.1111/bph.70316 |
| 関連URL | isVersionOf https://doi.org/10.1111/bph.70316 |
| フルテキストURL | fulltext.pdf |
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| 著者 | Matsuoka, Daiki| Suehara, Kana| Naka, Shuhei| Misaki, Taro| Nagasawa, Yasuyuki| Ito, Seigo| Suehiro, Yuto| Nomura, Ryota| Nakano, Kazuhiko| Matsumoto-Nakano, Michiyo| |
| キーワード | bacterial surface proteins collagen-binding protein human immunoglobulins IgA nephropathy Streptococcus mutans |
| 発行日 | 2026-01-07 |
| 出版物タイトル | Frontiers in Cellular and Infection Microbiology |
| 巻 | 15巻 |
| 出版者 | Frontiers Media SA |
| 開始ページ | 1673581 |
| ISSN | 2235-2988 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2026 Matsuoka, Suehara, Naka, Misaki, Nagasawa, Ito, Suehiro, Nomura, Nakano and Matsumoto-Nakano. |
| 論文のバージョン | publisher |
| PubMed ID | 41574301 |
| DOI | 10.3389/fcimb.2025.1673581 |
| Web of Science KeyUT | 001665990400001 |
| 関連URL | isVersionOf https://doi.org/10.3389/fcimb.2025.1673581 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kong, Dezheng| Funabiki, Nobuo| Kyaw, Htoo Htoo Sandi| Kotama, I Nyoman Darma| Zhu, Zihao| Rahmadani, Alfiandi Aulia| |
| キーワード | internet of things AI retrieval-augmented generation vector database schema-based extraction data sheet technical information |
| 発行日 | 2026-02-07 |
| 出版物タイトル | Sensors |
| 巻 | 26巻 |
| 号 | 4号 |
| 出版者 | MDPI AG |
| 開始ページ | 1081 |
| ISSN | 1424-8220 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2026 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/s26041081 |
| 関連URL | isVersionOf https://doi.org/10.3390/s26041081 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Haz, Amma Liesvarastranta| Brata, Komang Candra| Funabiki, Nobuo| Kyaw, Htoo Htoo Sandi| Fajrianti, Evianita Dewi| Sukaridhoto, Sritrusta| |
| キーワード | slide annotation multimodal analysis speech-to-text LLM SUS |
| 発行日 | 2026-02-01 |
| 出版物タイトル | Algorithms |
| 巻 | 19巻 |
| 号 | 2号 |
| 出版者 | MDPI AG |
| 開始ページ | 110 |
| ISSN | 1999-4893 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2026 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/a19020110 |
| 関連URL | isVersionOf https://doi.org/10.3390/a19020110 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Wardani, Ni Wayan| Funabiki, Nobuo| Kyaw, Htoo Htoo Sandi| Zhu, Zihao| Kotama, I Nyoman Darma| Sugiartawan, Putu| Putra, I Nyoman Agus Suarya| |
| キーワード | database programming SQL query description problem (SDP) self-study programming learning assistant system (PLAS) generative AI |
| 発行日 | 2026-01-09 |
| 出版物タイトル | Information |
| 巻 | 17巻 |
| 号 | 1号 |
| 出版者 | MDPI AG |
| 開始ページ | 65 |
| ISSN | 2078-2489 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2026 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/info17010065 |
| Web of Science KeyUT | 001670537100001 |
| 関連URL | isVersionOf https://doi.org/10.3390/info17010065 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Permatasari, Perwira Annissa Dyah| Mentari, Mustika| Kinari, Safira Adine| Aung, Soe Thandar| Funabiki, Nobuo| Kyaw, Htoo Htoo Sandi| Wai, Khaing Hsu| |
| キーワード | Java programming learning JPLAS JUnit code writing problem plagiarism Levenshtein distance threshold IQR AI-generated |
| 発行日 | 2025-12-26 |
| 出版物タイトル | Analytics |
| 巻 | 5巻 |
| 号 | 1号 |
| 出版者 | MDPI AG |
| 開始ページ | 2 |
| ISSN | 2813-2203 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2025 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/analytics5010002 |
| 関連URL | isVersionOf https://doi.org/10.3390/analytics5010002 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Zhu, Zihao| Funabiki, Nobuo| Sandi Kyaw, Htoo Htoo| Kotama, I Nyoman Darma| Pradhana, Anak Agung Surya| Rahmadani, Alfiandi Aulia| Noprianto| |
| キーワード | IoT MQTT protocol AI-assisted learning exercise-based education Python programming docker learning platform |
| 発行日 | 2025-12-18 |
| 出版物タイトル | Electronics |
| 巻 | 14巻 |
| 号 | 24号 |
| 出版者 | MDPI AG |
| 開始ページ | 4967 |
| ISSN | 2079-9292 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2025 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/electronics14244967 |
| Web of Science KeyUT | 001646413000001 |
| 関連URL | isVersionOf https://doi.org/10.3390/electronics14244967 |
| JaLCDOI | 10.18926/AMO/70075 |
|---|---|
| フルテキストURL | 80_1_069.pdf |
| 著者 | Wakatsuki, Shinya| Sakamoto, Shinya| Ueno, Akiko| Namba, Takaomi| Yamamoto, Yorito| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| |
| 抄録 | Patients with hepatocellular carcinoma (HCC) and extensive peritoneal dissemination generally have a poor prognosis and are often resistant to systemic therapy. We report the case of a 47-year-old woman with HCC and massive peritoneal dissemination who presented with malignant ascites requiring repeated cell-free and concentrated ascites reinfusion therapy and peritoneovenous shunt placement, as well as malignant pleural effusion requiring pleurodesis. Combined immunotherapy with durvalumab/tremelimumab was initiated;however, disease progression was observed after three treatment courses, prompting a switch to lenvatinib therapy. Two months after initiation of lenvatinib, CT imaging demonstrated complete disappearance of arterial enhancement in the primary hepatic lesion, along with reduction in the size of peritoneal dissemination nodules. Thirteen months after switching to lenvatinib (16 months after the initial diagnosis), the alpha-fetoprotein level continued to decrease, and the disease remained stable under treatment. Despite the extremely high tumor burden, lenvatinib achieved disease stabilization and symptomatic improvement. |
| キーワード | diagnostic laparoscopy hepatocellular carcinoma peritoneal dissemination lenvatinib |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2026-02 |
| 巻 | 80巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 69 |
| 終了ページ | 74 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2026 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 41748152 |
| Web of Science KeyUT | 001712986800001 |
| JaLCDOI | 10.18926/AMO/70074 |
|---|---|
| フルテキストURL | 80_1_063.pdf |
| 著者 | Takasu, Eri| Shiode, Yusuke| Kindo, Hiroya| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Kanzaki, Yuki| Morita, Tetsuro| Adachi, Takuya| Otsuka, Motoyuki| Morizane, Yuki| |
| 抄録 | A 77-year-old man undergoing treatment for hepatocellular carcinoma (HCC) presented with blurred vision in his right eye, persisting for 2 months. Slit-lamp microscopy and fundus examination revealed inflammatory cells in the anterior chamber, severe vitreous opacities, and retinal vasculitis in the right eye. The patient underwent vitreous surgery with biopsy, and vitreous cytology confirmed a metastatic intraocular tumor originating from the HCC. Radiotherapy was administered to the right eye, with no recurrence of intraocular inflammation observed at 10 months post-irradiation. |
| キーワード | metastatic intraocular tumor hepatocellular carcinoma panuveitis uveitis masquerade syndrome |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2026-02 |
| 巻 | 80巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 63 |
| 終了ページ | 67 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2026 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 41748151 |
| Web of Science KeyUT | 001712997700001 |
| JaLCDOI | 10.18926/AMO/70073 |
|---|---|
| フルテキストURL | 80_1_055.pdf |
| 著者 | Akazawa, Hidemasa| Hagiya, Hideharu| Fukushima, Shinnosuke| Yamamoto, Shohei| Nakano, Yasuhiro| Otsuka, Fumio| |
| 抄録 | In Japan, antiviral agents for COVID-19 were freely available until September 2023 as part of national policy. This study evaluated changes in these agents’ prescribing patterns and the patient outcomes following the policy shift. We conducted a multicenter retrospective study at four hospitals in Japan’s Okayama and Kagawa prefectures from January 2022 to March 2024. The study period was divided into the public-expenditure phase (January 2022 to September 2023) and the post-expenditure phase (October 2023 to March 2024). We extracted the hospitalized patients’ clinical data from the electronic database. The study’s primary outcome was the antiviral prescription rate; the secondary outcome was in-hospital mortality. Among the 302 hospitalized patients (median age 85 years), 52.0% were classified as having a mild condition. Of the patients with mild conditions, 37.7% were diagnosed in outpatient settings prior to hospitalization. During the public-expenditure phase, 47.4% of the patients received antivirals as outpatients, mainly molnupiravir (80.9%). In the post-expenditure period, 80.0% of the patients were prescribed antivirals, mostly molnupiravir (91.7%). The antiviral prescription rate was significantly higher after the policy change. The overall in-hospital mortality was 15.8%, with no significant difference between the two periods (17.0% vs. 10.5%). Despite the termination of government funding, antiviral prescriptions remained frequent at community hospitals located in highly aging regions of western Japan such as Okayama and Kagawa prefectures. Mortality remains high among the elderly, highlighting the need for continued antiviral therapy and booster vaccinations. |
| キーワード | coronavirus disease 2019 public expenditure prescribing pattern prognosis Japan |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2026-02 |
| 巻 | 80巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 55 |
| 終了ページ | 62 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2026 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 41748150 |
| Web of Science KeyUT | 001712994500007 |
| JaLCDOI | 10.18926/AMO/70072 |
|---|---|
| フルテキストURL | 80_1_047.pdf |
| 著者 | Eguchi, Yukiomi| Ushio, Soichiro| Irie, Keiichi| Yamashita, Yuta| Eguchi, Miyu| Nakano, Takafumi| Mishima, Kenichi| |
| 抄録 | Deregulation of cannabis use is gradually expanding in Europe and the United States. However, the biological processes driving tolerance to delta-9-tetrahydrocannabinol (Δ9-THC), the main psychoactive component of cannabis, remain unclear. Thus, this study aimed to investigate the mechanisms and time course of tolerance development and loss to Δ9-THC in mice. Male ICR mice (7 weeks old) were administered Δ9-THC once daily for 3 days and then divided into three groups according to the washout period (3-, 10-, and 17-day washout groups). After each washout, changes in body temperature and locomotor activity were measured following re-exposure to Δ9-THC. Furthermore, the mRNA expression levels of CB1 and CB2 receptors in the brain were evaluated using real-time PCR. On day 1, significant hypothermia and reduced spontaneous locomotor activity were observed in the Δ9-THC-treated mice compared with the vehicle-treated mice. Tolerance to the hypothermic and locomotor-suppressing effects of Δ9-THC developed on days 2 and 3, respectively, and dissipated after 3 and 11 days of washout, respectively. These differences in the rates of tolerance development and recovery may reflect distinct underlying mechanisms. No significant changes in receptor mRNA expression were observed. These findings highlight the complexity of Δ9-THC tolerance and its potential implications for long-term cannabis use. |
| キーワード | delta-9-tetrahydrocannabinol cannabis tolerance locomotor hypothermic |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2026-02 |
| 巻 | 80巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 47 |
| 終了ページ | 54 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2026 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 41748149 |
| Web of Science KeyUT | 001712994500006 |
| JaLCDOI | 10.18926/AMO/70071 |
|---|---|
| フルテキストURL | 80_1_039.pdf |
| 著者 | Tezel, Nihal| Can, Aslı Gençay| |
| 抄録 | The study aimed to determine the prevalence of kinesiophobia in patients who had undergone lumbar microdiscectomy and to examine its associations with pain intensity, disability, quality of life, depression, anxiety, and satisfaction with surgery. Forty-eight patients with microdiscectomy and 48 healthy controls were enrolled. The Tampa Scale for Kinesiophobia (TSK), Roland-Morris Disability Index (RMDI), Hospital Anxiety and Depression Scale (HADS-A and HADS-D, respectively), and Short Form-36 Health Survey (SF-36) were administered to both groups. The scores of TSK, RMDI, HADS-A, and HADS-D were significantly higher and SF-36 scores were significantly lower in the microdiscectomy than the control group (p<0.001 for all). In the microdiscectomy group, median (min-max) RMDI, HADS-A, and HADS-D scores were 19 (4-34), 10 (0-18), and 9 (0-18), respectively, in kinesiophobic patients, and were significantly higher than 6 (2-20), 3 (0-11), 2.5 (0-11) in non-kinesiophobic patients (all p<0.001). The median (min-max) SF-36 PCS, SF-36 MCS, and VAS scores for surgery satisfaction were 36.5 (8.7-75), 52.1 (11-95), 5, 5 (0-10), respectively, in kinesiophobic patients and were significantly lower than 71 (28-95), 85.5 (9-93), 8.5 (3-10) in non-kinesiophobic patients (all p<0.05). TSK scores were significantly correlated with RMDI, HADS-A, HADS-D, SF-36, and surgery satisfaction scores (all p<0.05). Kinesiophobic patients with lumbar microdiscectomy therefore showed greater disability and psychological morbidity, poorer quality of life, and lower satisfaction with surgery. |
| キーワード | kinesiophobia microdiscectomy disability quality of life depression |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2026-02 |
| 巻 | 80巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 39 |
| 終了ページ | 46 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2026 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 41748148 |
| Web of Science KeyUT | 001712994500005 |
| JaLCDOI | 10.18926/AMO/70070 |
|---|---|
| フルテキストURL | 80_1_031.pdf |
| 著者 | Ishibashi, Kyota| Oishi, Hirotaka| Araki, Ryo| Kawamura, Kosuke| Sasaki, Isamu| Sasaki, Eiji| Kamada, Hikaru| Kogawa, Masakazu| Tanaka, Sunao| Numasawa, Takuya| Ishibashi, Yasuyuki| |
| 抄録 | We investigated global alignment changes following total hip arthroplasty (THA) and predictive alignment parameters for increased cup anteversion (CA) by retrospectively analyzing the primary THA data of 75 patients treated at our hospital (49 women, 26 men; age 65.1±5.7 years, BMI 28.3±3.4 kg/m2). Global alignment parameters, i.e., the anterior pelvic plane angle (APPa) and proximal femoral shaft angle (PFSa) and other alignment parameters were measured. CA was evaluated based on the patients’ standing coronal radiographs. ΔCA was defined as the difference in CA from 2 weeks before to 1 year after each THA. We classified the cases as stable (S) (CA < 10°; n=63) and pelvic retroversion (R) (CA ≥ 10°; n=12) groups. Associations between ΔCA and alignment parameters were evaluated by linear regression and a receiver operating characteristic (ROC) analysis. A significant decrease in the PFSa occurred between the 2-week and 1-year post-THA timepoints (7.8±4.3° vs. 4.2±3.6°, p<0.001), with no notable change in other alignment parameters. At 1-year post-THA, the CA of 12 (16%) patients had increased to 4.5±4.4°. Only the preoperative APPa was positively associated with ΔCA (β=0.165, p=0.020). The ROC analysis revealed that the optimal cut-off value for increased CA in the APPa is 2.1° (area under the curve, 0.700; p=0.020; odds ratio, 4.80). The APPa change predicted increased CA, which emphasizes the importance of the use of preoperative standing radiography for identifying the optimal cup positioning for post-THA changes in CA. |
| キーワード | total hip arthroplasty global alignment anterior pelvic plane cup anteversion pelvic tilt |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2026-02 |
| 巻 | 80巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 31 |
| 終了ページ | 37 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2026 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 41748147 |
| Web of Science KeyUT | 001712994500004 |
| JaLCDOI | 10.18926/AMO/70069 |
|---|---|
| フルテキストURL | 80_1_017.pdf |
| 著者 | Yano, Hideki| Takahata, Yoko| Yamaguchi, Takeshi| Saito, Shinya| |
| 抄録 | This study aimed to develop a scale enabling nurses to objectively evaluate their own stroke discharge support, as a basis for enhancing its overall effectiveness. A draft scale was created based on a literature review, and consisted of a 51-item, 5-point Likert-type questionnaire administered to ward nurses engaged in stroke discharge support at acute care hospitals. Factor analysis was performed to refine the scale. Construct validity was assessed using the known-groups method, and reliability was evaluated through internal consistency analysis. The resulting Stroke Discharge Support Evaluation Scale comprises 29 items across 5 factors, each rated on a 5-point Likert scale. Analysis of the data collected from 237 valid responses demonstrated good internal consistency and supported the scale’s construct validity. The Stroke Discharge Support Evaluation Scale is a reliable and valid tool enabling ward nurses in acute care hospitals to evaluate their own stroke discharge support. |
| キーワード | stroke discharge support scale development |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2026-02 |
| 巻 | 80巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 17 |
| 終了ページ | 30 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2026 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 41748146 |
| Web of Science KeyUT | 001712994500003 |
| JaLCDOI | 10.18926/AMO/70068 |
|---|---|
| フルテキストURL | 80_1_009.pdf |
| 著者 | Sugahara, Kentaro| Kondo, Takashi| Miyatake, Nobuyuki| Nishi, Hiroyuki| Ujike, Kazuhiro| Koumoto, Kiichi| Namio, Keiichi| Hishii, Shuhei| Katayama, Akihiko| Suzuki, Hiromi| Yamamoto, Yorimasa| |
| 抄録 | Appropriate treatments for chronic hemodialysis patients are a public health challenge in Japan. Sedentary behavior appears to be closely associated with these patients’ survival. We thus sought to develop a nomogram that predicts survival based on the duration of chronic hemodialysis patients’ sedentary behavior. One hundred twenty-four patients under chronic hemodialysis (73 men, 51 women, age 71.7±11.1 years) were enrolled in this cohort study. The patients wore a triaxial accelerometer that measured both their sedentary behavior, i.e., total sedentary behavior (minutes) and their maximum sedentary bouts (min) on non-hemodialysis days. We obtained the Kaplan-Meier curve and used the log-rank test and a Cox proportional hazards model to evaluate the relationship between the patients’ sedentary behavior and their survival. We also used a Cox proportional hazards model to develop a nomogram for the patients’ 5-year survival rate. Forty-six patients died during the follow-up period. When we stratified the patients by the medians of total sedentary behavior and maximum sedentary bouts, we observed significant between-group differences. After adjustment for confounding factors in a Cox proportional hazards model, total sedentary behavior and maximum sedentary bouts were identified as critical survival factors, and we generated a nomogram using an index of sedentary behavior. Our analysis results demonstrated that sedentary behavior on non-dialysis days was closely associated with the survival of the chronic hemodialysis patients, suggesting that a decrease in sedentary behavior would prolong their survival. The nomogram developed herein based on sedentary behavior may be useful for predicting the outcomes of chronic hemodialysis patients. |
| キーワード | nomogram chronic hemodialysis sedentary behavior Cox proportional hazards model Kaplan- Meier curve |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2026-02 |
| 巻 | 80巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 9 |
| 終了ページ | 16 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2026 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 41748145 |
| Web of Science KeyUT | 001712994500002 |
| JaLCDOI | 10.18926/AMO/70067 |
|---|---|
| フルテキストURL | 80_1_001.pdf |
| 著者 | Yamaoka, Hidenaru| Yoshida, Masashi| Sarashina, Toshihiro| Akagi, Satoshi| Miyoshi, Toru| Munemasa, Mitsuru| Nakamura, Kazufumi| Ito, Hiroshi| Yuasa, Shinsuke| |
| 抄録 | Venous thromboembolism (VTE) is a serious complication in patients with cancer. In this population, the presence of thrombi is often assessed at cancer diagnosis by measuring D-dimer levels, which have high sensitivity but low specificity for identifying VTE at this clinical time point. However, the usefulness of D-dimer measurement during anticoagulation therapy has not been fully established, despite its widespread use. In this retrospective observational study, we investigated whether D-dimer measurement during anticoagulation therapy in cancer patients could predict overt VTE at follow-up. The study included patients who underwent D-dimer testing and contrast-enhanced computed tomography between 30 and 100 days after initiation of anticoagulation therapy. Eighty-two patients were included: 60 with cancer and 22 without. The diagnostic performance of D-dimer for overt VTE was as follows: sensitivity, 85.7%; specificity, 87.2%; positive predictive value, 78.3%; and negative predictive value, 89.2%. These findings suggest that D-dimer measurement at follow-up has high sensitivity and specificity for overt VTE in cancer patients and may aid in assessing thrombotic status. Clinically, if anticoagulation therapy is continued until D-dimer levels become negative, the absence of overt VTE could be inferred without additional invasive testing. |
| キーワード | D-dimer venous thromboembolism cancer |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2026-02 |
| 巻 | 80巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 1 |
| 終了ページ | 7 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2026 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 41748144 |
| Web of Science KeyUT | 001712994500001 |
| タイトル（別表記） | David Graeber Pirate enlightment, or the real Libertalia |
|---|---|
| JaLCDOI | 10.18926/70066 |
| フルテキストURL | jdc_005_286.pdf |
| 著者 | 沢山 美果子| |
| Amo Type | 新刊紹介 (New Book) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2026-03 |
| 巻 | 5巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 286 |
| 終了ページ | 288 |
| ISSN | 2436-8326 |
| 資料タイプ | 一般雑誌記事 |
| 言語 | 日本語 |
| 著作権者 | © 2025 by RIDC |
| 論文のバージョン | publisher |
| タイトル（別表記） | Letter from Itō Miyoji to Suematsu Kenchō, held by the Inukai Bokudō Memorial Museum |
|---|---|
| JaLCDOI | 10.18926/70064 |
| フルテキストURL | jdc_005_273.pdf |
| 著者 | 前田 昌義| |
| Amo Type | 資料紹介 (Materials and data) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2026-03 |
| 巻 | 5巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 273 |
| 終了ページ | 278 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| 著作権者 | © 2025 by RIDC |
| 論文のバージョン | publisher |
| タイトル（別表記） | Biyō Kokugaku Kiroku (School records of the Okayama han in the Edo period) (5) |
|---|---|
| JaLCDOI | 10.18926/70063 |
| フルテキストURL | jdc_005_170.pdf |
| 著者 | 倉地 克直| |
| Amo Type | 資料紹介 (Materials and data) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2026-03 |
| 巻 | 5巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 170 |
| 終了ページ | 272 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| 著作権者 | © 2025 by RIDC |
| 論文のバージョン | publisher |