検索結果 47902 件
| JaLCDOI | 10.18926/14973 |
|---|---|
| タイトル（別表記） | Clinical significance of spa therapy in the treatment of patients with chronic obstructive pulmonary disease (COPD). A study on 520 patients with COPD admitted for last5 years. |
| フルテキストURL | 068_001_007.pdf |
| 著者 | 谷崎 勝朗| 御舩 尚志| 光延 文裕| 保崎 泰弘| 芦田 耕三| 柘野 浩史| 岩垣 尚志| 山本 和彦| |
| 抄録 | 1992年1月より1996年12月までの5力年間に当院へ入院した慢性閉塞性呼吸器疾患520例を対象に,疾患の種類,年齢,地域分布などについて検討を加えた｡1.最近5年間に当院へ入院した呼吸器疾患患者は588例で,このうち,慢性閉塞性呼吸器疾患患者は520例(88.4%)であった｡これらの慢性閉塞性呼吸器疾患のなかでは,気管支喘息が433例(83.3%)と最も多く,その他,慢性気管支炎19例,閉塞性細気管支炎33例,肺気腫35例であった｡2.慢性閉塞性呼吸器疾患の年齢別検討では,鳥取県内および遠隔地(鳥取県外)いずれの症例においても,60-69才および70才以上の症例が多い傾向が見られた｡3.入院患者の地域分布では,鳥取県内からの入院患者に比べ,遠隔地(鳥取県外)からの入院患者がより多く,その分布別検討では,岡山県,兵庫県,大阪腐,広島県,山口県,愛媛県からの入院患者が多い傾向が見られた｡ |
| キーワード | 慢性閉塞性呼吸器疾患 (COPD) 気管支喘息 (bronchial asthma) 温泉療法 (spa therapy) 高齢患者 (aged patients) 遠隔地 (distant area) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1997-12 |
| 巻 | 68巻 |
| 開始ページ | 1 |
| 終了ページ | 7 |
| ISSN | 0918-7839 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002308043 |
| JaLCDOI | 10.18926/14972 |
|---|---|
| タイトル（別表記） | 気管支喘息におけるアレルギー性鼻炎と花粉抗原に対するIgE抗体 |
| フルテキストURL | 068_022_027.pdf |
| 著者 | 御舩 尚志| 光延 文裕| 保崎 泰弘| 芦田 耕三| 柘野 浩史| 岡本 誠| 岩垣 尚史| 山本 和彦| 谷崎 勝朗| 越智 浩二| 原田 英雄| |
| 抄録 | IgE antibodies against inhalant allergens were estimated in 53 patients with bronchial asthma in relation to allergic rhinitis. Of them, 20 patients (37.7%) had allergic rhinitis. 1. Asthma + allergic rhinitis were often observed in patients between the ages of 0 and 39. In contrast, asthma alone in those over age 60. 2. A RAST score was positive in house dust mite (HDm)(50.9%), cockroach(24.5%), and Candida (26.4%) in these patients, and the positive rate was not different between patients with and without allergic rhinitis. 3. The frequency of positive RAST against Japanese cedar and rice plants was higher in patients with allergic rhinitis (42.9% and 18.5%) than in those without allergic rhinitis (28.6 and 3.7%), however, the each positive rate or RAST against the two allergens was not significantly different between those with AR and without AR. 4. The number of patients with AR induced by pollen alone (pollinosis) was not large ( 5/53, 9.4%) in the patients with asthma. It was clarified from the results that allergic rhinitis was often observed in asthma patients, but not pollinosis. and that IgE antibodies against Japanese cedar and rice plants were found even in patients without AR. |
| キーワード | bronchial asthma allergic rhinitis IgE antibodies house dust mite Japanese cedar |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1997-12 |
| 巻 | 68巻 |
| 開始ページ | 22 |
| 終了ページ | 27 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308327 |
| 著者 | 岡山大学医学部附属病院三朝分院| |
|---|---|
| 発行日 | 1998-12 |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 巻 | 69巻 |
| 資料タイプ | その他 |
| 著者 | 松原 扶美恵| 井上 妙子| 光延 彰子| 御舩 尚志| 谷崎 勝朗| |
|---|---|
| 発行日 | 1998-12 |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 巻 | 69巻 |
| 資料タイプ | データ・データベース |
| 著者 | 岡山大学医学部附属病院三朝分院看護部| |
|---|---|
| 発行日 | 1998-12 |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 巻 | 69巻 |
| 資料タイプ | その他 |
| JaLCDOI | 10.18926/14968 |
|---|---|
| フルテキストURL | 069_088_092.pdf |
| 著者 | 土海 智穂| 寺崎 佳代| 岡本 和代| 山田 修子| |
| 抄録 | 関節の変形と骨破壊を伴い,排泄動作に支障をきたしている慢性関節リウマチ患者に対し改良パンツの作成を試みた｡残存機能に合わせはきなれたパンツを=夫することにより,排泄動作が自立でき満足感が得られた｡ |
| キーワード | 慢性関節リウマチ 改良衣類 排泄自立 満足感 |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 88 |
| 終了ページ | 92 |
| ISSN | 0918-7839 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002308379 |
| 著者 | 徐 裕卿| |
|---|---|
| 発行日 | 2007-03-31 |
| 出版物タイトル | 文化共生学研究 |
| 巻 | 7巻 |
| 号 | 1号 |
| 資料タイプ | 紀要論文 |
| JaLCDOI | 10.18926/14967 |
| 著者 | 張 東震| |
|---|---|
| 発行日 | 2007-03-31 |
| 出版物タイトル | 文化共生学研究 |
| 巻 | 7巻 |
| 号 | 1号 |
| 資料タイプ | 紀要論文 |
| JaLCDOI | 10.18926/14966 |
| JaLCDOI | 10.18926/14965 |
|---|---|
| タイトル（別表記） | 膵癌における癌遺伝子および癌抑制遺伝子 |
| フルテキストURL | 069_082_087.pdf |
| 著者 | 越智 浩二| 松村 直樹| 一村 光子| 水島 孝明| 原田 英雄| 蓮岡 英明| 横山 元浩| 鶴見 哲也| 光延 文裕| 谷崎 勝朗| |
| 抄録 | Recent advances in molecular biology have revealed that a number of oncogenes (K-ras, erbB-2, and Met) and tumor suppressor genes (p53, p16, APC, and DCC) contribute to the development of pancreatic cancer. This paper reviewed the present knowledge of oncogenes and tumor suppressor genes relevant to pancreatic cancer. Further studies on molecular alterations in pancreatic cancer may lead to a better understanding of tumor biology, offering a possibility of development of new diagnostic and therapeutic approaches in the future. |
| キーワード | Pancreatic cancer oncogene tumor suppressor gene genetic mutation |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 82 |
| 終了ページ | 87 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308547 |
| JaLCDOI | 10.18926/14964 |
|---|---|
| タイトル（別表記） | The effects of perilla seed oil ointment for atopic dermatitis |
| フルテキストURL | 069_076_081.pdf |
| 著者 | 宮本 美由紀| 穐山 千晶| 能見 美智代| 高田 純子| 西村 伸子| 中村 寿美江| 川上 恭弘| 岡本 誠| 芦田 耕三| 光延 文裕| 谷崎 勝朗| |
| 抄録 | 近年アトピー性皮膚炎が増加しており,工ゴマ油を使った食事療法がアレルギー抑制に有用であることが報告されている｡そこで今回,エゴマ油を外用剤として使用するため,亜鉛華単軟膏を基剤とした工コマ軟膏を作製し,アトピー性皮膚炎患者3例を対象にその臨床応用を試みた｡その結果,掻痒感の軽減に効果がみられ,また皮膚症状では,丘疹.表皮剥離,苔癬化,落屑などの所見が改善される傾向が見られた｡ |
| キーワード | アトピー性皮膚炎 エゴマ軟膏 掻痒感 |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 76 |
| 終了ページ | 81 |
| ISSN | 0918-7839 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002308418 |
| JaLCDOI | 10.18926/14963 |
|---|---|
| タイトル（別表記） | サーモグラフィーによる体表面温度の測定 2.温水負荷の効果 |
| フルテキストURL | 069_068_075.pdf |
| 著者 | 保崎 泰弘| 高田 真吾| 光延 文裕| 御舩 尚志| 芦田 耕三| 柘野 浩史| 岡本 誠| 原田 誠之| 谷崎 勝朗| 越智 浩二| 原田 英雄| 辻 孝夫| |
| 抄録 | The body surface temperature of 41 patients suffering coldness, numbness or pain in their feet was examined using thermography. Thermographic results were analyzed quantitatively by calculating a recovery ratio as: Recovery ratio =[Total counts of thermography (Pixels) over temperature (T) after cold loading] ÷ [Initial counts over T before cold loading] x 100(%). Three different baseline temperatures, 26℃. 27℃ and 28℃, were used in processing the thermographic results into pictures. The recovery ratio was susceptible to temperature, and we recommend a baseline temperature limitation of 27℃ for clinical study. A bi-modal distribution of recovery ratio was observed in 18 patients with diabetes mellitus. One group (6 subjects) had high recovery ratio between 80%-100%, and another group (10 subjects) had a low recovery ratio between 0%-19%. The results of thermography were also influenced by weather. To reduce the effect of outside temperature, we used pre-loading with hot water at 36℃ for 5 min (hot loading). A large difference in recovery ratio between presence and absence of hot loading was observed in 6 of the 30 subjects. The difference was over-estimated in more than 20% of recovery ratio without hot loading as compared with hot loading in these 6 subjects. The effect of drugs on peripheral circulation, such as beraprost sodium and sarpogrelate hydrochloride, was clear and quantified using thermography under these conditions of hot loading. |
| キーワード | サーモグラフィー (thermography) 糖尿病 (diabetes mellitus) 末梢循環 (peripheral circulation) 冷水負荷 (cold loading) 温水負荷 (hot loading) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 68 |
| 終了ページ | 75 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308316 |
| JaLCDOI | 10.18926/14962 |
|---|---|
| タイトル（別表記） | ステロイド依存性重症難治性気管支喘息症例における胃粘膜病変の検討 |
| フルテキストURL | 069_063_067.pdf |
| 著者 | 御舩 尚志| 光延 文裕| 保崎 泰弘| 芦田 耕三| 柘野 浩史| 原田 誠之| 岡本 誠| 湯本 英一朗| 高田 真吾| 谷崎 勝朗| |
| 抄録 | Recently, we experienced two asthmatic patients with advanced gastric cancer. The two patients had steroid-dependent intractable asthma (SDIA) who had been on administration of corticosteroids for more than 2 years. To determine the influence of pathophysiology of SDIA on stomach mucous lesion, gastroscopic examinations and immunological examinations were performed in eight patients with SDIA, compared with 25 patient with non-SDIA. In patients with SDIA, gastric cancer, its precursor condition and immunosuppressive state were observed. These results suggest that the immunosuppressive state in SDIA induced by the long-term administration of corticosteroids may lead to the risk of gastric cancer development. |
| キーワード | ステロイド依存性重症難治性 (steroid-dependent intractable asthma (SDIA)) 胃癌 (gastric cancer) 免疫抑制 (immunosuppression) リンパ球 (lymphocytes) IgG |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 63 |
| 終了ページ | 67 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308665 |
| JaLCDOI | 10.18926/14961 |
|---|---|
| タイトル（別表記） | 鼻腔･副鼻腔疾患を合併する気管支喘息症例に対するクラリスロマイシン投与の効果 |
| フルテキストURL | 069_057_062.pdf |
| 著者 | 御舩 尚志| 光延 文裕| 保崎 泰弘| 芦田 耕三| 柘野 浩史| 原田 誠之| 岡本 誠| 湯本 英一朗| 高田 真吾| 谷崎 勝朗| |
| 抄録 | We experienced a case of 59-year-old woman with intractable asthma, who had aspirin intolerance. Despite various treatments including systemic corticosteroid administration, she was often admitted due to severe asthma attacks. Furthermore, she had allergic rhinitis and sinusitis. Computed tomography (CT) scans of sinonasal cavity revealed marked thickness of nasal mucosa and air-fluid level in maxillary sinuses. Although her asthma symptoms such as wheezing and dyspnea were improved by administration of bronchodilator, systemic corticosteroids and beclomethasone diisoccyanate (BDI) accompanied with spa therapy, her peak expiratory flow (PEF) showed no improvement. After readmission due to asthma attacks, clarithromycin (CAM) administration for sinonasal disorders was started. The PEF value showed marked improvement after starting CAM administration, and pulmonary functions and bronchial hyperresponsiveness were also improved. It is suggested from her clinical course that CAM may have beneficial effects in asthmatic patients with sinonasal disorders. |
| キーワード | bronchial asthma allergic rhinitis sinusitis clarithromycin peak expiratory flow (PEF) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 57 |
| 終了ページ | 62 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308388 |
| JaLCDOI | 10.18926/14960 |
|---|---|
| タイトル（別表記） | n-3系脂肪散を強化した食事療法が有効と考えられた肺気腫の一例 |
| フルテキストURL | 069_049_056.pdf |
| 著者 | 柘野 浩史| 芦田 耕三| 光延 文裕| 御舩 尚志| 岡本 誠| 保崎 泰弘| 谷崎 勝朗| 辻 孝夫| |
| 抄録 | An effective treatment for the advanced stages of chronic obstructive pulmonary disease (COPD) has not been established yet. We report our recent experience of one patient with pulmonary emphysema treated by dietary supplementation of n-3 fatty acid for two months. He presented improvements in clinical symptoms and pulmonary function, and suppression of leukotriene B(4) generation by peripheral leukocytes. We consequently suppose that dietary treatment with n-3 fatty acids (perilla seed oil) may offer benefits for the treatment of pulmonary emphysema by competitively inhiabiting the conversion of arachidonicacid to leukotrienes and prostanoids. |
| キーワード | pulmonary emphysema n-3 fatty acid leukotriene diet therapy |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 49 |
| 終了ページ | 56 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308253 |
| JaLCDOI | 10.18926/14959 |
|---|---|
| タイトル（別表記） | n-3系脂肪酸食の気管支喘息に対する臨床効果:n-6系脂肪酸との比較 |
| フルテキストURL | 069_040_048.pdf |
| 著者 | 岡本 誠| 芦田 耕三| 光延 文裕| 御舩 尚志| 保崎 泰弘| 柘野 浩史| 原田 誠之| 湯本 英一朗| 高田 真吾| 谷崎 勝朗| 片岡 幹男| 原田 実根| |
| 抄録 | N-3 fatty acids, such as fish oil, have been reported to have some beneficial effects in patients with bronchial asthma by suppressing leukocyte function, followed by reduction of the need for pharmacologic agents. To examine the effects of dietary supplementation with perilla seed oil rich in α-linolenic acid (ALA), 23 patients with asthma took corn oil rich in linoleic acid (LA) for the former two weeks, perilla seed oil for the later two weeks. The asthmatic patients were classified into two groups by the changes of the generation of leukotrienes B4 (LTB4), C4 (LTC4), and B5 (LTB5) during the two courses of dietary modification: one was sensitive to dietary modification, and the other was insensitive to dietary supplementation. We compared the two groups in clinical characteristics. Significant differences were observed in peak flow (PEF), forced expiratory volume in one second (FEV1.0), IgE, sex, obesity index (OI), concentration of serum total cholesterol, albumin, low density lipoprotein {LDL)-cholesterol, β-lipoprotein and phospholipids between two groups. This study indicated that these factors influence the generation of LTB4, C4 and B5 of asthmatic patients in dietary supplementation. |
| キーワード | n-3系脂肪酸 (n-3 fatty acids) エゴマ油 (perilla seed oil) 気管支喘息 (bronchial asthma) LTB4 LTC4 |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 40 |
| 終了ページ | 48 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308199 |
| 著者 | 周 光輝| 殷 冬水| |
|---|---|
| 発行日 | 2007-03-31 |
| 出版物タイトル | 文化共生学研究 |
| 巻 | 7巻 |
| 号 | 1号 |
| 資料タイプ | 紀要論文 |
| JaLCDOI | 10.18926/14958 |
| 著者 | 荒木 勝| |
|---|---|
| 発行日 | 2007-03-31 |
| 出版物タイトル | 文化共生学研究 |
| 巻 | 7巻 |
| 号 | 1号 |
| 資料タイプ | その他 |
| JaLCDOI | 10.18926/14956 |
|---|---|
| タイトル（別表記） | MR-angiographyで経過を観察しえた慢性関節リウマチに合併した巨細胞動脈炎の1例 |
| フルテキストURL | 069_035_039.pdf |
| 著者 | 原田 誠之| 光延 文裕| 兒玉 富美子| 保崎 泰弘| 御舩 尚志| 柘野 浩史| 岡本 誠| 湯本 英一朗| 高田 真吾| 谷崎 勝朗| |
| 抄録 | We report a patient who developed giant cell (temporal) arteritis during treatment of rheumatoid arthritis. The patient was a 57-year-old Japanese woman and had been well controlled with anti-rheumatic drugs, when she presented to our hospital with severe bitemporal headaches and marked fatigue. An exclusive diagnosis was rapidly made and she was diagnosed as having giant cell arteritis based on the classification criteria by American College of Reumatology. Additionally, magnetic resonance (MR) angiography was performed, from which stenotic change in the bilateral superficial temporal arteries was strongly suspected and then corticosteroid therapy was quickly started. The patient followed an uneventful course without developing any complications such as visual dysfunctions. Therapeutic effect was confirmed by MR-angiographic findings obtained 4 weeks after the initiation of therapy. |
| キーワード | 巨細胞動脈炎 (giant cell arteritis) 側頭動脈炎 (temporal arteritis) 慢性関節リウマチ (rheumatoid arthritis) MRアンギオグラフィー (MR-angiography) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 35 |
| 終了ページ | 39 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308121 |
| JaLCDOI | 10.18926/14955 |
|---|---|
| タイトル（別表記） | 気管支喘息患者における努力肺活量(% FVC)の低下と気道炎症ならびに臨床病型との関連 |
| フルテキストURL | 069_028_034.pdf |
| 著者 | 光延 文裕| 御舩 尚志| 保崎 泰弘| 芦田 耕三| 横田 聡| 柘野 浩史| 谷崎 勝朗| 越智 浩二| 原田 英雄| |
| 抄録 | Clinical features of asthmatics with a low % FVC (<80%) were studied in relation to airway inflammation and clinical asthma types. 1. Twenty four (75.0%) of the 32 subjects with a low % FVC had steroid-dependent intractable asthma. 2. A significant association between % FVC value and clinical asthma type was found. The value of % FVC was significantly lower in subjects with type II asthma (bronchiolar obstruction), in which significantly decreased proportion of lymphocytes,and significantly increased proportion of neutrophils in bronchoalveolar lavage (BAL) fluid were observed, than in those with type la-1 (simple bronchoconstriction) with (P<0.001) and without glucocorticoid therapy (P<0.02). 3. The % FVC value was significantly improved after treatment in type lb (hypersecretion) with BAL eosinophilia, but not in those with type II with BAL neutrophilia. These results demonstrate that marked decrease of % FVC in patients with asthma correlated with airway inflammation, and that airway reversibility by medication is very low in patients with type II asthma. |
| キーワード | ventilatory function FEV1.0 bronchoalveolar lavage bronchial reversibility |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 28 |
| 終了ページ | 34 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308252 |
| JaLCDOI | 10.18926/14954 |
|---|---|
| タイトル（別表記） | 肺気腫患者における吸入抗原に対するIgE抗体 |
| フルテキストURL | 069_021_027.pdf |
| 著者 | 光延 文裕| 御舩 尚志| 保崎 泰弘| 芦田 耕三| 柘野 浩史| 岡本 誠| 原田 誠之| 湯本 英一郎| 高田 真吾| 谷崎 勝朗| 越智 浩二| 原田 英雄| 長谷川 晴巳| |
| 抄録 | To analyze the pathophysiological changes ot the airways in emphysema, bronchial responsiveness and the generation of leukotrienes B4 (LTB4) and C4 (LTC4) by peripheral leucocytes were examined in 22 patients with emphysema. The subjects were divided into two groups according to the presence or absence of IgE antibodies against inhalant allergens; RAST positive group and RAST negative group. 1. Smoking history, mean CT number and mean maximum % low attenuation area (% LAA) <-950HU of the lung on high resolution computed tomography (HRCT), and DLco value suggested that there were emphysematous changes of the lung in all subjects. However, these findings were not different between the two groups. 2. The level of serum IgE was significantly higher in RAST positive group than in RAST negative group. 3. The mean % increase in FEV1.0 after inhalation of β-agonists was higher in RAST positive group than in RAST negative group. The % increase more than 15% was found in 4 of the 9 subjects (44.4%) in RAST positive group and 2 of the 12 (16.7%) in RAST negative group. 4. The generation of LTC4 by leucocytes was significantly higher in RAST positive group than in RAST negative group (p<0.01). The generation of LTB4 was not significantly different between the two groups. The results suggest that IgE-mediated allergy participates in the bronchial responsiveness of patients with emphysema. |
| キーワード | emphysema bronchial responsiveness FEV1.0 LTB4 LTC4 |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1998-12 |
| 巻 | 69巻 |
| 開始ページ | 21 |
| 終了ページ | 27 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308178 |