| ID | 40756 |
| フルテキストURL | |
| タイトル（別表記） | Studies of the treatment of pulmonary epidermoid carcinoma Part 2. Thermochemotherapy in human epidermoid carcinoma cells in culture
|
| 著者 |
瀬戸 匠
岡山大学医学部第二内科学教室
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| 抄録 | The effectiveness of hyperthermia in combination with anticancer drugs on EBC-1 cell line established from a patient with pulmonary epidermoid carcinoma was investigated. Anticancer drugs tested in the present study were adriamycin, bleomycin, cisdichlorodiammineplatinum (II) and mitomycin C. EBC-1 cells were incubated with the drug for one hour at 37°C or at elevated temperature (41°C, 42°C and 43°C). The enhancement of cytotoxicity by hyperthermia was found in combination with all of the drugs. The degree of enhanced cytotoxicity was positively elated to the temperature in combinations with adriamycin and bleomycin. Especially, a synergic enhancement of cytotoxicity was found with the combination of hyperthermia and bleomycin. The present study showed that the combination of hyperthermia and anticancer drugs produced potential cytotoxicity on EBC-1 cells in vitro, and may provide useful information for the clinical trials in the future.
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| キーワード | human lung cancer cell line
thermochemotherapy
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| 発行日 | 1989-06
|
| 出版物タイトル |
岡山医学会雑誌
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| 出版物タイトル（別表記） | Journal of Okayama Medical Association
|
| 巻 | 101巻
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| 号 | 5-6号
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| 出版者 | 岡山医学会
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| 出版者（別表記） | Okayama Medical Association
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| 開始ページ | 581
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| 終了ページ | 588
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| ISSN | 0030-1558
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| NCID | AN00032489
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| 資料タイプ |
学術雑誌論文
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| オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/101/5-6/101_5-6_581/_article/-char/ja/
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| 関連URL | http://www.okayama-u.ac.jp/user/oma/
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| 言語 |
日本語
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| 著作権者 | 岡山医学会
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| 論文のバージョン | publisher
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| 査読 |
有り
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| Eprints Journal Name | joma
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