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フルテキストURL fulltext.pdf
著者 Watanabe, Kenta| Katsui, Kuniaki| Sugiyama, Soichiro| Yoshio, Kotaro| Kuroda, Masahiro| Hiraki, Takao| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu|
キーワード Clinical pathology Elderly Non-small cell lung carcinoma Radiosurgery Stereotactic body radiation therapy
発行日 2021-02-23
出版物タイトル Radiation Oncology
16巻
1号
出版者 BMC
開始ページ 39
ISSN 1748-717X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2021.
論文のバージョン publisher
PubMed ID 33622369
DOI 10.1186/s13014-021-01769-7
Web of Science KeyUT 000623175000001
関連URL isVersionOf https://doi.org/10.1186/s13014-021-01769-7
フルテキストURL fulltext.pdf
著者 Hiraoka, Sakiko| Takashima, Shiho| Inokuchi, Toshihiro| Nakarai, Asuka| Takahara, Masahiro| Harada, Keita| Seki, Yasuhiro| Watanabe, Katsunori| Kato, Jun| Okada, Hiroyuki|
キーワード Colitis ulcerative Fecal calprotectin Quantitative fecal immunochemical test Latex agglutination turbidimetric immunoassay Mucosal healing
発行日 2018-12-14
出版物タイトル Intestinal Research
17巻
2号
出版者 Korean Association for the Study of Intestinal Diseases
開始ページ 202
終了ページ 209
ISSN 1598-9100
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Copyright 2019. Korean Association for the Study of Intestinal Diseases
論文のバージョン publisher
PubMed ID 30541228
DOI 10.5217/ir.2018.00086
Web of Science KeyUT 000466136800006
関連URL isVersionOf https://doi.org/10.5217/ir.2018.00086
JaLCDOI 10.18926/AMO/61442
フルテキストURL 75_1_95.pdf
著者 Minato, Keitaro| Hirano, Toru| Kawashima, Hiroyuki| Yamagishi, Tetsuro| Watanabe, Keigo| Ohashi, Masayuki| Ogose, Akira| Endo, Naoto|
抄録 A 21-year-old man consulted our hospital for treatment of a spinal giant cell tumor (GCT) of Enneking stage III. Lower lumbar-spine tumors and severe spinal canal stenosis are associated with high risk for surgical mor-bidity. Stability was temporarily secured with a percutaneous pedicle screw fixation in combination with deno-sumab, which shrank the tumor. Total en bloc spondylectomy was then performed 6 months after initiation of denosumab, and the patient was followed for 3 years. There was no local recurrence, and bony fusion was obtained. Minimally invasive surgery and denosumab allowed safer and easier treatment of a collapsing lower lumbar extra-compartmental GCT.
キーワード spinal stabilization denosumab spondylectomy giant cell tumor
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 95
終了ページ 101
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649620
JaLCDOI 10.18926/AMO/61440
フルテキストURL 75_1_91.pdf
著者 Shiotania, Toshio| Yamamoto, Hiromasa| Katsube, Riko| Tomioka, Yasuaki| Suzawa, Ken| Miyoshi, Kentaroh| Otani, Shinji| Okazaki, Mikio| Sugimoto, Seiichiro| Sohb, Junichi| Yamane, Masaomi| Toyooka, Shinichi|
抄録 Bronchopleural fistula (BPF) is a severe complication following lung resection. We present the case of a patient with a history of advanced lung cancer, who had undergone induction chemoradiotherapy followed by right middle and lower lobectomy, and who developed BPF after completion right pneumonectomy. Although we had covered the bronchial stump with an omental pedicled flap, BPF was found on postoperative day 19. We covered the fistula with n-butyl-2-cyanoacrylate (NBCA) using bronchoscopy. Although we had to repeat the NBCA treatment, we ultimately cured the patient’s BPF and no recurrence was observed up to 15.2 months after surgery.
キーワード bronchopleural fistula pneumonectomy induction chemoradiotherapy n-butyl-2-cyanoacrylate (NBCA) omental pedicled flap
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 91
終了ページ 94
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649619
JaLCDOI 10.18926/AMO/61437
フルテキストURL 75_1_71.pdf
著者 Sanki, Tomoaki| Tetsunaga, Tomonori| Furumatsu, Takayuki| Yamada, Kazuki| Kawamura, Yoshi| Ozaki, Toshifumi|
抄録 Intra-operative acetabular fracture is a total hip arthroplasty complication that can occur during cementless cup insertion, especially in osteoporotic patients. We conducted this biomechanical study to investigate the impact resistance of the acetabulum with simulated bones of different density by drop-weight impact testing. Low- and high-density polyurethane foam blocks were used as osteoporotic and healthy bone models, respectively. Polyurethane blocks were used as the acetabular cancellous bone. Composite sheets were used as the acetabu-lum’s medial cortex. The testing revealed that the osteoporotic bone model’s impact resistance was significantly lower than that the healthy bone model’. In the healthy bone model, even thin acetabular cancellous bone with ≥ 1 mm acetabulum medial cortex was less likely to fracture. In the osteoporotic bone model, fracture was pos-sible without ≥ 1 mm medial cortex of the acetabulum and thick acetabular cancellous bone. Although impac-tion resistance differs due to bone quality, the impaction resistance in this osteoporotic bone model was equiv-alent to that healthy bone model’s when a thick medial wall was present. To avoid intra-operative acetabulum fracture, surgeons should consider both the bone quality and the thicknesses of the medial cortex and acetabu-lar cancellous bone.
キーワード intra-operative acetabular fracture drop weight impact testing total hip arthroplasty impact resistance
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 71
終了ページ 77
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649616
JaLCDOI 10.18926/AMO/61435
フルテキストURL 75_1_55.pdf
著者 Kubo, Yujiro| Watanabe, Mototsugu| Choshi, Haruki| Matsubara, Kei| Shiotani, Toshio| Kataoka, Kazuhiko|
抄録 Small pulmonary lesions are often difficult to localize during thoracoscopic surgery. We describe a new com-puted tomography (CT)-guided pleural dye-marking method for small peripheral pulmonary lesions that does not involve a visceral pleural puncture. We used this technique for 23 lesions (22 patients) who underwent tho-racoscopic partial lung resection (Nov. 2016-Jan. 2018). With the patient in the lateral decubitus position, pre-operative CT-guided marking on the skin over the lesion was performed. During the surgery, we marked the visceral pleura with a skin marker directly or with an infant-size nutrition catheter with crystal violet at the tip through a venous indwelling needle inserted perpendicular to the skin marking. We localized and resected the lesions in all cases, without complications. The median nodule size measured histopathologically was 8 (4-20) mm overall, and 7 (0-20) mm of the solid part; the median distance from the visceral pleura to the nodule was 9 (1-33) mm. The median operation time was 67 (37-180) min. The median postoperative hospital stay was 3 (3-11) days. Our CT-guided pleural dye-marking method is useful and safe for the localization of small periph-eral pulmonary lesions in thoracoscopic partial lung resections.
キーワード Small pulmonary lesion ground glass nodule marking localization thoracocentesis
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 55
終了ページ 61
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649614
JaLCDOI 10.18926/AMO/61431
フルテキストURL 75_1_31.pdf
著者 Miyamaru, Satoru| Murakami, Daizo| Nishimoto, Kohei| Saito, Haruki| Miyamoto, Yusuke| Hirota, Kaoruko| Ise, Momoko| Orita, Yorihisa|
抄録 Although the lung is the most common site of distant metastases from head and neck squamous cell carcinoma (HNSCC), the number of reports about the effects of pulmonary metastasectomy for the treatment of lung metastasis from HNSCC is limited. Metachronous pulmonary metastases were detected in 45 HNSCC patients at Kumamoto University Hospital from 1998 to 2018. Twenty-two patients underwent an operative resection (Ope group) and 23 underwent chemotherapy (Chemo group). The 3-year overall survival (OS) rate and median OS were evaluated. The effects of adjuvant chemotherapy after pulmonary metastasectomy and of new drugs (cetuximab and nivolumab), in the chemo group were also assessed. The 3-year OS rates and median OS were: Ope, 66.1% and 31.5 months; Chemo, 39.7% and 18 months, respectively. In the Ope group, addi-tional recurrences were significantly fewer in the patients who underwent adjuvant chemotherapy post-surgery versus the patients who underwent surgery alone (p = 0.013). In the Chemo group, the 3-year OS rate of the patients who received new drugs was significantly better than that of the patients who did not (p = 0.021). Adjuvant chemotherapy after pulmonary metastasectomy may be a preferable treatment option for preventing recurrences. Cetuximab and nivolumab have a potential to improve OS.
キーワード pulmonary metastasis head and neck squamous cell carcinoma pulmonary metastasectomy adjuvant chemotherapy
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 31
終了ページ 37
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649611
JaLCDOI 10.18926/AMO/61430
フルテキストURL 75_1_25.pdf
著者 Tetsunaga, Tomonori| Tetsunaga, Tomoko| Yamada, Kazuki| Sanki, Tomoaki| Kawamura, Yoshi| Ozaki, Toshifumi|
抄録 In bipolar hemiarthroplasty (BHA), it is important to preserve soft tissue to reduce the risk of postoperative dislocation. A variety of surgical approaches for BHA are available, but extra care is needed with muscle- and tendon-preserving approaches in geriatric patients. We investigated the usefulness of BHA using a conjoined tendon-preserving posterior (CPP) approach, in which only the external obturator muscle is dissected, in geri-atric patients. We retrospectively analyzed the cases of 40 femoral neck fracture patients (10 men, 30 women) aged ≥ 80 years who underwent BHA using the CPP approach. The patients’ average age was 85.8 years (80-94 years). We examined the operation time, bleeding, preservation of short external rotator muscles, complica-tions, and stem alignment and subsidence from postoperative radiographs. Although gemellus inferior muscle injury was detected in 4 patients (10%), the hip joint stability was very excellent in all cases. There was no intraoperative fracture or postoperative dislocation. On postoperative radiographs, all femoral stems were in a neutral position. There was no stem subsidence in all 40 patients. BHA using the CPP approach appeared to be useful even in geriatric patients.
キーワード bipolar hip arthroplasty geriatric patient conjoined tendon-preserving posterior approach
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 25
終了ページ 30
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649610
フルテキストURL fulltext.pdf
著者 YASUHARA, Takao| MURAI, Satoshi| MIKUNI, Nobuhiro| MIYAMOTO, Susumu| DATE, Isao|
キーワード artificial bone cranioplasty infection re-operation titanium plate
発行日 2020
出版物タイトル Neurologia medico-chirurgica
60巻
7号
出版者 The Japan Neurosurgical Society
開始ページ 337
終了ページ 350
ISSN 0470-8105
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by The Japan Neurosurgical Society
PubMed ID 32536658
DOI 10.2176/nmc.oa.2020-0051
Web of Science KeyUT 000548315700003
関連URL isVersionOf https://doi.org/10.2176/nmc.oa.2020-0051
フルテキストURL fulltext.pdf
著者 Toh, Norihisa| Kotani, Yasuhiro| Akagi, Teiji| Kuroko, Yosuke| Baba, Kenji| Otsuki, Shin-ichi| Kasahara, Shingo| Ito, Hiroshi|
キーワード Pulmonary atresia with intact ventricular septum adult congenital heart disease outcome
発行日 2020-06-17
出版物タイトル Congenital Heart Disease
15巻
1号
出版者 Wiley
開始ページ 1
終了ページ 11
ISSN 1747-079X
NCID AA12157082
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン publisher
DOI 10.32604/CHD.2020.011579
Web of Science KeyUT 000564363500001
関連URL isVersionOf https://doi.org/10.32604/CHD.2020.011579
フルテキストURL fulltext.pdf
著者 Takagi, Kosei | Kimenai, Hendrikus J. A. N.| Terkivatan, Turkan| Tran, Khe T. C.| Ijzermans, Jan N. M.| Minnee, Robert C.|
キーワード Kidney transplantation Living donors Nephrectomy Laparoscopy Hand-assisted laparoscopy Learning curve Education Teaching
発行日 2020-06-15
出版物タイトル Surgical Endoscopy
出版者 Springer
ISSN 0930-2794
NCID AA10750363
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The authors.
論文のバージョン publisher
PubMed ID 32556762
DOI 10.1007/s00464-020-07727-w
Web of Science KeyUT 000540992500014
関連URL isVersionOf https://doi.org/10.1007/s00464-020-07727-w
フルテキストURL fulltext.pdf
著者 Shimada, Yasushi| Yoshiyama, Masahiro| Tagami, Junji| Sumi, Yasunori|
キーワード Optical coherence tomography Diagnosis Caries Tooth crack NCCL Tooth wear Age-related changes
発行日 2020-11
出版物タイトル Japanese Dental Science Review
56巻
1号
出版者 ELSEVIER SCI LTD
開始ページ 109
終了ページ 118
ISSN 1882-7616
NCID AA12334461
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
PubMed ID 33033549
DOI 10.1016/j.jdsr.2020.08.001
Web of Science KeyUT 000598681800015
関連URL isVersionOf https://doi.org/10.1016/j.jdsr.2020.08.001
JaLCDOI 10.18926/AMO/61211
フルテキストURL 74_6_521.pdf
著者 Itazaki, Yujiro| Tsujimoto, Hironori| Sugasawa, Hidekazu| Yaguchi, Yoshihisa| Nomura, Shinsuke| Ito, Nozomi| Harada, Manabu| Sugihara, Takao| Tsuchiya, Satoshi| Ishibashi, Yusuke| Kouzu, Keita| Kishi, Yoji| Ueno, Hideki |
抄録 We report a successful dissection of metastatic posterior thoracic para-aortic lymph node (No. 112aoP) via bilateral thoracoscopic surgery. With the anesthetized patient (a 73-year-old Japanese woman) in the prone position, two working ports were inserted for the left-side approach, and artificial pneumothorax was created. Thoracoscopic examination revealed a swollen LN posterior to the descending aorta. Fat and metastatic LNs posterior to the aorta were dissected from the aortic arch level to the diaphragm while preserving intercostal arteries. For the right-side approach, two working ports were inserted and a routine thoracoscopic esophagec-tomy was performed. Gastric conduit reconstruction was achieved laparoscopically. Operation time for the left thoracic procedure: 54 min; estimated blood loss: almost none. No recurrence was detected 24 months post-operatively. There are several surgical options for approaching No. 112aoP, including transhiatal, left thora-cotomy, and thoracoscopy. Although a wide dissection of the posterior thoracic para-aortic area has not been reported, it may be feasible and safe if the artery of Adamkiewicz and intercostal arteries are preserved. A min-imally invasive bilateral thoracoscopic approach for a thoracoscopic esophagectomy is safe and useful for esophageal cancer patients with solitary No. 112aoP metastasis.
キーワード bilateral approach posterior thoracic para-aortic lymph node thoracoscopic esophagectomy
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2020-12
74巻
6号
出版者 Okayama University Medical School
開始ページ 521
終了ページ 524
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33361872
Web of Science KeyUT 000601203600008
NAID 120006948950
フルテキストURL fulltext.pdf
著者 Nishii, Kazuya| Ohashi, Kadoaki| Tamura, Tomoki| Ninomiya, Kiichiro| Matsubara, Takehiro| Senoo, Satoru| Kano, Hirohisa| Watanabe, Hiromi| Oda, Naohiro| Makimoto, Go| Higo, Hisao| Kato, Yuka| Ninomiya, Takashi| Kubo, Toshio| Yamamoto, Hiromasa | Tomida, Shuta| Hotta, Katsuyuki| Tabata, Masahiro| Toyooka, Shinichi| Maeda, Yoshinobu| Kiura, Katsuyuki|
キーワード non-small cell lung cancer epidermal growth factor receptor mutations droplet digital PCR exhaled breath condensate EGFR-TKIs
発行日 2020-12
出版物タイトル Oncology Letters
20巻
6号
出版者 Spandidos Publications
開始ページ 393
ISSN 1792-1074
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン publisher
PubMed ID 33193853
DOI 10.3892/ol.2020.12256
Web of Science KeyUT 000595649300005
関連URL isVersionOf https://doi.org/10.3892/ol.2020.12256
フルテキストURL fulltext.pdf
著者 Shimada, Yasushi| Yoshiyama, Masahiro| Tagami, Junji| Sumi, Yasunori|
キーワード Optical coherence tomography Diagnosis Caries Tooth crack NCCL Tooth wear Age-related changes
発行日 2020-11-30
出版物タイトル Japanese Dental Science Review
56巻
1号
出版者 Elsevier
開始ページ 109
終了ページ 118
ISSN 1882-7616
NCID AA12334461
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン publisher
PubMed ID 33033549
DOI 10.1016/j.jdsr.2020.08.001
Web of Science KeyUT 000598681800015
関連URL isVersionOf https://doi.org/10.1016/j.jdsr.2020.08.001
フルテキストURL fulltext210412_3.pdf
著者 Asano, Takao| Osaki, Yusuke|
キーワード Decision analysis Investment analysis Capital investment Smooth ambiguity model Technology shock
備考 © 2020 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.ejor.2020.11.047] . |
発行日 2020-12-05
出版物タイトル European Journal of Operational Research
293巻
1号
出版者 Elsevier
開始ページ 304
終了ページ 311
ISSN 03772217
NCID AA0017802X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
DOI 10.1016/j.ejor.2020.11.047
Web of Science KeyUT 000628803700022
関連URL isVersionOf https://doi.org/10.1016/j.ejor.2020.11.047
フルテキストURL fulltext.pdf
著者 Shahriar, Abu Saleh Muhammad| Ono, Shintaro| Nakayama, Masaaki| Ohara, Naoko| Ohara, Naoya|
キーワード Porphyromonas gingivalis Periodontal diseases Gingipain Bacterial secretion system
備考 © 2020 Japanese Association for Oral Biology. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.job.2020.09.007] .|
発行日 2020-12
出版物タイトル Journal of Oral Biosciences
62巻
4号
出版者 Elsevier
開始ページ 322
終了ページ 326
ISSN 1349-0079
NCID AA11896386
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 Japanese Association for Oral Biology.
論文のバージョン author
PubMed ID 33038516
DOI 10.1016/j.job.2020.09.007
Web of Science KeyUT 000597154900005
関連URL isVersionOf https://doi.org/10.1016/j.job.2020.09.007
フルテキストURL fulltext.pdf
著者 Miyaji, Mary| Furuta, Ryohei| Hosoya, Osamu| Sano, Kuniaki| Hara, Norikazu| Kuwano, Ryozo| Kang, Jiyoung| Tateno, Masaru| Tsutsui, Kimiko M.| Tsutsui, Ken|
キーワード Biochemistry Molecular biology
発行日 2020-10-29
出版物タイトル Scientific Reports
10巻
1号
出版者 Nature Research
開始ページ 18550
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2020
論文のバージョン publisher
PubMed ID 33122676
DOI 10.1038/s41598-020-75004-w
Web of Science KeyUT 000587689500013
関連URL isVersionOf https://doi.org/10.1038/s41598-020-75004-w
フルテキストURL fulltext.pdf
著者 Kashiwa, Misa| Shimada, Yasushi| Sadr, Alireza| Yoshiyama, Masahiro| Sumi, Yasunori| Tagami, Junji|
キーワード occlusal tooth wear erosive tooth wear SS-OCT 3D imaging enamel thickness dentin exposure demineralization
発行日 2020-10-23
出版物タイトル Sensors
20巻
21号
出版者 MDPI
開始ページ 6016
ISSN 1424-8220
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by the authors.
論文のバージョン publisher
PubMed ID 33113981
DOI 10.3390/s20216016
Web of Science KeyUT 000589312100001
関連URL isVersionOf https://doi.org/10.3390/s20216016
フルテキストURL fulltext.pdf Fig1-5.pdf
著者 Matsumoto, Kazuyuki| Kato, Hironari| Horiguchi, Shigeru| Uchida, Daisuke| Tomoda, Takeshi| Muro, Shinichiro| Okada, Hiroyuki|
発行日 2019-09
出版物タイトル Endoscopy
51巻
9号
出版者 Thieme Gruppe
開始ページ E265
終了ページ E266
ISSN 0013-726X
NCID AA00635110
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 31071749
DOI 10.1055/a-0896-2498
Web of Science KeyUT 000484585300014
関連URL isVersionOf https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-0896-2498