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著者 真田 浩|
発行日 1959-09-20
出版物タイトル 岡山医学会雑誌
71巻
10-1号
資料タイプ 学術雑誌論文
著者 遠藤 徹|
発行日 1959-09-20
出版物タイトル 岡山医学会雑誌
71巻
10-1号
資料タイプ 学術雑誌論文
著者 中島 行正|
発行日 1959-09-20
出版物タイトル 岡山医学会雑誌
71巻
10-1号
資料タイプ 学術雑誌論文
著者 吉川 浩二|
発行日 1959-09-20
出版物タイトル 岡山医学会雑誌
71巻
10-1号
資料タイプ 学術雑誌論文
著者 吉川 浩二|
発行日 1959-09-20
出版物タイトル 岡山医学会雑誌
71巻
10-1号
資料タイプ 学術雑誌論文
著者 秦泉寺 圭|
発行日 1959-09-10
出版物タイトル 岡山医学会雑誌
71巻
9-2号
資料タイプ 学術雑誌論文
著者 田川 和夫|
発行日 1959-08-10
出版物タイトル 岡山医学会雑誌
71巻
8-1号
資料タイプ 学術雑誌論文
著者 加茂 成人|
発行日 1959-08-10
出版物タイトル 岡山医学会雑誌
71巻
8-1号
資料タイプ 学術雑誌論文
著者 加茂 成人|
発行日 1959-08-10
出版物タイトル 岡山医学会雑誌
71巻
8-1号
資料タイプ 学術雑誌論文
著者 大越 祐一|
発行日 1989-06
出版物タイトル 岡山医学会雑誌
101巻
5-6号
資料タイプ 学術雑誌論文
著者 梶木 秀樹|
発行日 1989-08-31
出版物タイトル 岡山医学会雑誌
101巻
7-8号
資料タイプ 学術雑誌論文
著者 突沖 満則|
発行日 1990-12
出版物タイトル 岡山医学会雑誌
102巻
11-12号
資料タイプ 学術雑誌論文
著者 池田 敏夫|
発行日 1990-10
出版物タイトル 岡山医学会雑誌
102巻
9-10号
資料タイプ 学術雑誌論文
著者 岡崎 良夫|
発行日 1990-06
出版物タイトル 岡山医学会雑誌
102巻
5-6号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/40508
フルテキストURL 64_5_323.pdf
著者 Kanaoka, Yuji| Inagaki, Ei-ichirou| Hamanaka, Souhei| Masaki, Hisao| Tanemoto, Kazuo|
抄録 The transient systemic low perfusion that occurs during cardiovascular surgery leads to oxidative stress and the production of free radicals. A systemic increase of various markers of oxidative stress has been shown to occur during cardiopulmonary bypass (CPB). However, these markers have not been adequately evaluated because they seem to be reactive and short-lived. Here, oxidative stress was measured using the free radical analytical system (FRAS 4) assessing the derivatives of reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP). Blood samples were taken from 21 patients undergoing elective cardiovascular surgery. CPB was used in 15 patients, and abdominal aortic aneurysm (AAA) surgery without CPB was performed in 6. Measurements of d-ROMs and BAP were taken before surgery, 1 day, 1 week, and 2 weeks after surgery, and oxidative stress was evaluated. The d-ROM level increased gradually after cardiovascular surgery up to 2 weeks. Over time, the d-ROM level after surgery involving CPB became higher than that after AAA surgery. This difference reached statistical significance at 1 week and lasted to 2 weeks. The prolongation of CPB was prone to elevate the d-ROM level whereas the duration of the aortic clamp in AAA surgery had no relation to the d-ROM level. The BAP was also elevated after surgery, and was positively correlated with the level of d-ROMs. In this study, patients who underwent cardiovascular surgery involving CPB had significant oxidative damage. The production of ROMs was shown to depend on the duration of CPB. Damage can be reduced if CPB is avoided. When CPB must be used, shortening the CPB time may be effective in reducing oxidative stress.
キーワード oxidative stress reactive oxygen metabolites (ROM) extracorporeal circulation (ECC)
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2010-10
64巻
5号
出版者 Okayama University Medical School
開始ページ 323
終了ページ 330
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2010 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 20975766
Web of Science KeyUT 000283563300008
JaLCDOI 10.18926/40179
タイトル(別表記) Study on effects of balneotherapy on blood pH, P(CO(2)) and P(O(2)) Part 3. The effects of balneotherapeutical procedures on blood pH, P(CO(2)) and P(O(2))
フルテキストURL 038_027_044.pdf
著者 八幡 隆昭|
抄録 The effects of balneological procedures as well as the duration of hospitalization on blood pH, P(CO(2)) and P(O(2)) were studied in fifty-two patients chiefly including rheumatoid arthritics. The changes of these parameters in sixty minutes after any foment were discussed comparing with those in the control groups. The results were as follows. 1) Blood pH decreased in value from first to second hospital week and thereafter remained almost constant. No P(CO(2)) variation was observed. The P(O(2)) remained stable till third hospital week and then followed by up and down changes during the forth to the ninth week. 2) The arterial blood pH, P(CO(2)) and P(O(2)) in all showed a tendency to increase after the general spring bath of ten minutes duration (bath temp. : 40±1℃). The venous blood pH and P(O(2)) also increased as in the arterial but P(CO(2)) decreased. These non significcant changes in the venous blood were considered to be resulted from the increased cutaneous blood flow in the forearm. 3) It was showed that mud bath of twenty minutes duration (bath temp. : 40±1℃) made an influence on the venous blood pH, P(CO(2)) and P(O(2)) via two different mechanisms. The first is the increased blood flow which had five minute value of P(O(2)) and pH elevated but P(CO(2)) reduced significantly. The second is the prominent increase of oxygen uptake in which the significant reduction of five minute P(O(2)) value but no variation of pH or P(CO(2)) was demonstrated. It was suggested that these two types of variations were based on the difference of individual response to heat. 4) The signiilcant blood pH, P(CO(2)) and P(O(2)) changes after mud pack of twenty minutes duration (surface temp. : 40~50℃) were considered to reflect the increased blood flow. 5) The increased cutaneous blood flow induced by balneotherapeutical procedures was proved to remain as long as sixty minutes thereafter in almost all cases. 6) The blood pH, P(CO(2)) and P(O(2)) changes observed in the control groups were related mainly with the increased blood flow and only little, if any, with the elevated oxygen uptake.
出版物タイトル 岡山大学温泉研究所報告
発行日 1969-03-20
38巻
開始ページ 27
終了ページ 44
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 40017532344
JaLCDOI 10.18926/40162
タイトル(別表記) Isotopic study of Hot Springs in Japan, I Techniques for oxygen isotopic analysis of spring water
フルテキストURL pitsr_040_033_040.pdf
著者 松葉谷 治| 酒井 均| 田中 ひな子| 上村 多鶴恵|
抄録 The CO(2)-H(2)O isotopic equilibration technique was studied for the routine analyses of the oxygen isotopic ratios of hot spring water. A reaction vessel containing 2 ml of water and 0.16 m mole of tank CO(2) was shaken for 18 hrs. in a constant-temperature bath at 25.0℃ (Figs. 1, 2, and 3), and the CO(2) was analyzed for the oxygen isotopic ratio by a MCKINNEY type mass spectrometer. Several aliquots of 1, 2 and 5 ml from a same water were each analyzed three times by successive equilibration (Table 1). The observed values differ depending on the volume of water but the corrected values by equation (6) indicate excellent agreement, implying the whole processes to be well controlled. The reproducibility of the isotopic analyses is better than ± 0.1‰ (Table 2) in most cases, and the accuracy would not be worse than ± 0.2‰ as demonstrated by the interlaboratory comparison of some standard samples (Table 3). Oxygen isotopic ratios of water from more than 70 hot springs in Japan are presented (Table 5). Although the results will be discussed in the following issues of this series of paper, most hot spring water have the δ(18)O values similar to those of meteoric waters in Japan. However, spring water from Arima Hot Springs, Hyogo-Pref., which has been known by its abnormally high chloride and low sulfate concentrations is of an exceptionally high δ(18)O value.
出版物タイトル 岡山大学温泉研究所報告
発行日 1971-03-26
40巻
開始ページ 33
終了ページ 40
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002398154
JaLCDOI 10.18926/40150
タイトル(別表記) On the measurement of oxygen and carbon isotopic ratios of carbonates
フルテキストURL pitsr_041_009_012.pdf
著者 渡辺 洵| 松葉谷 治|
抄録 Oxygen and carbon isotopic ratios of two working standards of our laboratory and three other standards were measured by McCrea's technique and the new McKINNEY type mass spectrometer in this Institute. The reproducibility of δ(13)C measurement is about ±0.2‰. Some systematic differences in δ(18)O values were observed among the three measurements in Apr.-May, July, and Aug., 1971. Because these systematic differences are supposed to be caused by the imperfection in the processes of decomposition of carbonates by phosphoric acid, the reproducibility of δ(18)O measurement may be ±O.2‰ in most cases. The calibrations of our working standard, CK-13, against the PDB standard were carried out on the assumption that δ(18)O and δ(13)C of CK-13 are -1.75‰ and +O.54‰ relative to PDB, respectively. The accuracy of these calibrations is about ±O.2‰ as shown by the interlaboratory comparison of some standards (Table 3). The δ(18)O values of the two working standards relative to PDB are independently recalculated relative to SMOW based on the two assumptions (Table 4). One of which is that a standard water MSA-2 is -8.20‰ relative to SMOW, and the other is that the δ(18)O of CK-13 is -1.75‰ relative to PDB. The results of both calculations agree within 0.4‰.
出版物タイトル 岡山大学温泉研究所報告
発行日 1972-03-25
41巻
開始ページ 9
終了ページ 12
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002398149
JaLCDOI 10.18926/40149
タイトル(別表記) A subsequent report on the new McKinney type mass spectrometer in the Institute for Thermal Spring Research, Okayama University
フルテキストURL pitsr_041_003_007.pdf
著者 松葉谷 治|
抄録 Since the installation in April 1970, the McKinney type mass spectrometer has maintained a good condition and about 5000 isotopic analyses of oxygen, carbon and sulfer has been cerried out so far. The ion source filament was changed to spiral one from single wire. Consequently three times sensitivity and the longer life of filament were obtained. Gradual changes in the ratio of potential divider (β) and the sensitivity (|△ E(0)(2)|/E(0)(1)) for the difference of β have been observed (Table 1). Because these changes are opposite in trend but similar in degree, it is supposed that these changes are caused by decrease of feed-back resister value in the balancing system. Although there remain some problems in the corrections for the difference in observed isotopic tatio between two cases that a same CO(2) is fed to ion source from the ST side of inlet system on the one hand and from the X side on the another, the reproducibility of the measurement of isotopic ratio for long period is about ±O.1‰ (Table 2, Fig. 1). δ(18)O values of standard waters, MSA-1 and MSA-2, measured during a period from May to Dec. 1970 and in Sep. 1971 yielded good agreements implying the reproducibility of the measurement to be constant (Table 3). Both calculated δ(18)O values relative to a given sample based on each observed δ(18)O value relative to two different samples agreed each other. It is concluded that the linearity of observed a-value holds over a range of 30‰ (Table 4).
出版物タイトル 岡山大学温泉研究所報告
発行日 1972-03-25
41巻
開始ページ 3
終了ページ 7
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002398147
JaLCDOI 10.18926/40148
タイトル(別表記) The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique
フルテキストURL pitsr_041_001_002.pdf
著者 松葉谷 治|
抄録 The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique was studied. In this study, a new type of reaction vessel was used (Fig. 1). The reaction time for equilibration using this new reaction vessel was nearly equal to that in the previous study (Fig. 2). The oxygen isotopic ratios of each two samples of pH 2, 4, 7, 8, 9, and 10 were measured. There is no significant difference between the observed δ(18)O values of these samples (Table 1). Therefore it is concluded that the effect of pH of water needs not to be taken into account on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique.
出版物タイトル 岡山大学温泉研究所報告
発行日 1972-03-25
41巻
開始ページ 1
終了ページ 2
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002398148