検索結果 - 岡山大学学術成果リポジトリ

An imaging‑based diagnostic approach to vascular anomalies of the oral and maxillofacial region

フルテキストURL	fulltext20230828-03.pdf
著者	Al‑Hammad, Wlla\| Fujikura, Mamiko\| Hisatomi, Miki\| Okada, Shunsuke\| Munhoz, Luciana\| Kawazu, Toshiyuki\| Takeshita, Yohei\| Fujita, Mariko\| Yanagi, Yoshinobu\| Asaumi, Jun-Ichi\|
キーワード	vascular anomalies magnetic resonance imaging computed tomography dynamic contrast-enhanced magnetic resonance imaging contrast index curve
発行日	2023-07-27
出版物タイトル	Oncology Letters
巻	26巻
号	3号
出版者	Spandidos Publications
開始ページ	394
ISSN	1792-1074
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 Al-Hammad et al.
論文のバージョン	publisher
PubMed ID	37600333
DOI	10.3892/ol.2023.13980
Web of Science KeyUT	001049518700001
関連URL	isVersionOf https://doi.org/10.3892/ol.2023.13980

Augmented reality-based affective training for improving care communication skill and empathy

フルテキストURL	fulltext.pdf
著者	Nakazawa, Atsushi\| Iwamoto, Miyuki\| Kurazume, Ryo\| Nunoi, Masato\| Kobayashi, Masaki\| Honda, Miwako\|
発行日	2023-07-10
出版物タイトル	PLoS ONE
巻	18巻
号	7号
出版者	Public Library of Science
開始ページ	e0288175
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 Nakazawa et al.
論文のバージョン	publisher
PubMed ID	37428739
DOI	10.1371/journal.pone.0288175
Web of Science KeyUT	001027854200002
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0288175

Trends in Head and Neck Cancer Mortality from 1999 to 2019 in Japan: An Observational Analysis

フルテキストURL	fulltext.pdf
著者	Higashionna, Tsukasa\| Harada, Keisaku\| Maruo, Akinari\| Niimura, Takahiro\| Tan, Elizabeth\| Vu, Quynh Thi\| Kawabata, Takayoshi\| Ushio, Soichiro\| Hamano, Hirofumi\| Kajizono, Makoto\| Zamami, Yoshito\| Ishizawa, Keisuke\| Harada, Ko\| Hinotsu, Shiro\| Kano, Mitsunobu R.\| Hagiya, Hideharu\| Koyama, Toshihiro\|
キーワード	head and neck cancer mortality joinpoint regression trend analysis
発行日	2023-07-26
出版物タイトル	Cancers
巻	15巻
号	15号
出版者	MDPI
開始ページ	3786
ISSN	2072-6694
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
PubMed ID	37568602
DOI	10.3390/cancers15153786
Web of Science KeyUT	001046110700001
関連URL	isVersionOf https://doi.org/10.3390/cancers15153786

Design and Analysis of Hybrid-Excitation Variable Flux Memory Motor for Traction Applications: Improving Output Power in High-Speed Area During Six-Step Operation Mode

フルテキストURL	fulltext.pdf
著者	Tsunata, Ren\| Yokomichi, Keito\| Takemoto, Masatsugu\| Imai, Jun\|
キーワード	Variable flux memory motor hybrid excitation motor traction applications EV HEV six-step operation one-pulse drive output power density
発行日	2023-08-03
出版物タイトル	IEEE Access
巻	11巻
出版者	Institute of Electrical and Electronics Engineers
開始ページ	82024
終了ページ	82036
ISSN	2169-3536
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	publisher
DOI	10.1109/ACCESS.2023.3301809
Web of Science KeyUT	001047221300001
関連URL	isVersionOf https://doi.org/10.1109/ACCESS.2023.3301809

Features and Evolution of Global Energy Trade Patterns from the Perspective of Complex Networks

フルテキストURL	fulltext.pdf
著者	Cong, Yingnan\| Hou, Yufei\| Jiang, Jiaming\| Chen, Shuangzi\| Cai, Xiaojing\|
キーワード	energy trade complex networks topology evolutionary properties
発行日	2023-07-28
出版物タイトル	Energies
巻	16巻
号	15号
出版者	MDPI
開始ページ	5677
ISSN	1996-1073
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
DOI	10.3390/en16155677
Web of Science KeyUT	001045434700001
関連URL	isVersionOf https://doi.org/10.3390/en16155677

Evidence for Hypoxia-Induced Shift in ATP Production from Glycolysis to Mitochondrial Respiration in Pulmonary Artery Smooth Muscle Cells in Pulmonary Arterial Hypertension

フルテキストURL	fulltext.pdf
著者	Akagi, Satoshi\| Nakamura, Kazufumi\| Kondo, Megumi\| Hirohata, Satoshi\| Udono, Heiichiro\| Nishida, Mikako\| Saito, Yukihiro\| Yoshida, Masashi\| Miyoshi, Toru\| Ito, Hiroshi\|
キーワード	glycolysis mitochondrial respiration pulmonary arterial hypertension pulmonary artery smooth muscle cells Seahorse technology hypoxia ATP production
発行日	2023-07-31
出版物タイトル	Journal of Clinical Medicine
巻	12巻
号	15号
出版者	MDPI
開始ページ	5028
ISSN	2077-0383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
PubMed ID	37568430
DOI	10.3390/jcm12155028
Web of Science KeyUT	001045690800001
関連URL	isVersionOf https://doi.org/10.3390/jcm12155028

Data-driven evolutionary computation for service constrained inventory optimization in multi-echelon supply chains

フルテキストURL	fulltext.pdf
著者	Liu, Ziang\| Nishi, Tatsushi\|
キーワード	Evolutionary algorithm Inventory management Data-driven Supply chain Digital twin
備考	The version of record of this article, first published in Complex & Intelligent Systems, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40747-023-01179-0\|
発行日	2023-08-09
出版物タイトル	Complex & Intelligent Systems
巻	10巻
号	1号
出版者	Springer
開始ページ	825
終了ページ	846
ISSN	2199-4536
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
DOI	10.1007/s40747-023-01179-0
Web of Science KeyUT	001044871100001
関連URL	isVersionOf https://doi.org/10.1007/s40747-023-01179-0

Co-occurrence of Three Systemic Diseases: ANCA-associated Vasculitis, Sjogren's syndrome and Sarcoidosis

フルテキストURL	fulltext.pdf
著者	Tsuji, Kenji\| Okuyama, Yuka\| Asano, Yosuke\| Yamaoka, Kimitomo\| Kitamura, Shinji\| Wada, Jun\|
キーワード	ANCA-associated vasculitis Sjogren's syndrome sarcoidosis monoclonal gammopathy of undetermined significance
発行日	2023-08-01
出版物タイトル	Internal Medicine
巻	62巻
号	15号
出版者	The Japanese Society of Internal Medicine
開始ページ	2215
終了ページ	2221
ISSN	0918-2918
NCID	AA10827774
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 The Japanese Society of Internal Medicine
論文のバージョン	publisher
PubMed ID	36450474
DOI	10.2169/internalmedicine.0966-22
Web of Science KeyUT	001045161600001
関連URL	isVersionOf https://doi.org/10.2169/internalmedicine.0966-22

イェーリング書簡集⑷（ゲッティンゲン時代：1872－92年②）

タイトル（別表記）	Die Übersetzung von Jherings Briefe（4）
フルテキストURL	olj_73_1_1_48.pdf
著者	平田公夫\|
出版物タイトル	岡山大學法學會雜誌
発行日	2023-08-18
巻	73巻
号	1号
開始ページ	48
終了ページ	1
ISSN	0386-3050
言語	日本語
論文のバージョン	publisher

A Boy Safely Treated with Tyrosine Kinase Inhibitors for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Osteolysis

JaLCDOI	10.18926/AMO/65757
フルテキストURL	77_4_439.pdf
著者	Shiwaku, Takahiro\| Ishida, Hisashi\| Tatebe, Yasuhisa\| Tamefusa, Kosuke\| Ochi, Motoharu\| Fujiwara, Kaori\| Kubo, Toshihide\| Nakata, Eiji\| Washio, Kana\| Tsukahara, Hirokazu\|
抄録	A three-year-old boy with Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia (Ph+ALL) presented with an osteolytic lesion in his right upper arm. Tyrosine kinase inhibitors (TKIs) such as imatinib and dasatinib are an essential component throughout the course of treatment for Ph+ALL. However, TKIs are reported to affect the bone metabolism. In the treatment course of the current patient, the osteolytic lesion quickly improved despite the continuous use of TKIs, even during the concomitant use of corticosteroids. This suggests that TKIs can be safely given with concomitant corticosteroids to children with Ph+ALL, even when osteolytic lesions are present.
キーワード	acute lymphoblastic leukemia children tyrosine kinase inhibitor osteolysis
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	439
終了ページ	442
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635146
Web of Science KeyUT	001088434900002

A Case of Acute Zonal Occult Outer Retinopathy in which Oct en Face Imaging Was Useful for Diagnosis and Follow-up

JaLCDOI	10.18926/AMO/65756
フルテキストURL	77_4_433.pdf
著者	Ono, Ryuki\| Shiode, Yusuke\| Kimura, Shuhei\| Hosokawa, Mio\| Matoba, Ryo\| Kanzaki, Yuki\| Kindo, Hiroya\| Morita, Tetsuro\| Morizane, Yuki\|
抄録	A 23-year-old woman presented with a 1-month history of visual abnormalities in her right eye. A visual field test revealed temporal abnormalities in the right eye. Optical coherence tomography revealed an indistinct ellipsoid zone (EZ) on the B-scan image and hyporeflective areas in the EZ layer on the en face image in the right eye. We diagnosed the patient with acute zonal occult outer retinopathy. Visual field tests and B-scan images improved to almost normal at 6 months, but hyporeflective areas remained on the en face images. Thus, en face images may be more sensitive at detecting abnormalities in the outer retina than other modalities.
キーワード	acute zonal occult outer retinopathy optical coherence tomography en face image ellipsoid zone
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	433
終了ページ	437
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635145
Web of Science KeyUT	001088434900001

An Unusual Presentation of Chest Pain and Laryngeal Discomfort in a Pregnant Woman: A Case Report and Literature Review

JaLCDOI	10.18926/AMO/65755
フルテキストURL	77_4_429.pdf
著者	Sasanami, Misa\| Iida, Atsuyoshi\| Iwamuro, Masaya\| Hirai, Ryousuke\| Obara, Takashi\| Tsukahara, Kohei\| Yumoto, Tetsuya\| Naito, Hiromichi\| Nakao, Atsunori\|
抄録	Intramural esophageal dissection (IED), characterized by bleeding into the submucosal space, leads to mucosal separation and dissection. The most prevalent symptoms are sudden chest or retrosternal pain, hematemesis, and dysphagia. Therefore, acute coronary syndrome and aortic dissection are among its most notable differential diagnoses. A 31-year-old pregnant woman presented with acute chest pain, laryngeal discomfort, and hematemesis. Emergency esophagogastroscopy revealed longitudinal mucosal dissection (upper esophagus to esophagogastric junction). The patient was successfully treated by avoiding the ingestion of solid foods. Clinicians should consider a diagnosis of IED for pregnant patients with acute chest pain, especially if hematemesis is present.
キーワード	chest pain dysphagia esophageal dissection hematemesis
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	429
終了ページ	431
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635144
Web of Science KeyUT	001163659800012

Accuracy of ultrasound vs. Fourier-domain optic biometry for measuring preoperative axial length in cases of rhegmatogenous retinal detachment

フルテキストURL	fulltext20230821-02.pdf fig1_20230821-02.pdf fig2_20230821-02.pdf fig3_20230821-02.pdf fig4_20230821-02.pdf fig5_20230821-02.pdf fig6_20230821-02.pdf
著者	Kimura, Shuhei\| Hosokawa, Mio Morizane\| Shiode, Yusuke\| Matoba, Ryo\| Kanzaki, Yuki\| Goto, Yasuhito\| Kanenaga, Keisuke\| Suzuki, Etsuji\| Morizane, Yuki\|
キーワード	Axial length Rhegmatogenous retinal detachment Macular detachment Fourier-domain optic biometry Ultrasound
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10384-023-01018-2\| This fulltext file will be available in Aug. 2024.\|
発行日	2023-08-10
出版物タイトル	Japanese Journal of Ophthalmology
巻	67巻
号	6号
出版者	Springer Science and Business Media LLC
開始ページ	645
終了ページ	651
ISSN	0021-5155
NCID	AA00691177
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Japanese Ophthalmological Society 2023
論文のバージョン	author
PubMed ID	37561309
DOI	10.1007/s10384-023-01018-2
Web of Science KeyUT	001045669100002
関連URL	isVersionOf https://doi.org/10.1007/s10384-023-01018-2

Acute Coronary Spasm Following Pelvic Fracture, Bleeding, and Shock in a Trauma Patient

JaLCDOI	10.18926/AMO/65753
フルテキストURL	77_4_423.pdf
著者	Yamakawa, Yasuaki\| Miyashita, Kohei\| Morizane, Atsushi\| Takeuchi, Masato\| Kawashima, Yuta\| Sugimura, Tomoko\| Saisaka, Yuichi\|
抄録	We report a case of a patient with severe pelvic fracture who showed concurrent ST elevation on electrocardiogram. A 70-year-old man incurred an unstable pelvic fracture from a motorcycle accident. On admission, he was hemodynamically unstable, and massive transfusion and noradrenaline were administered immediately. Although ST elevation was present in leads II, III, aVF, V5, and V6, cardiac function was preserved; thus, trans-arterial embolization and external fixation for pelvic fracture were given priority. Four days after the injury, he suffered a cardiac arrest, and coronary angiography revealed that the cause of ST elevation and cardiac arrest was coronary vasospasm. Physicians should be aware that pain-related stress and platelet activation as well as use of noradrenaline in severe trauma cases can induce coronary vasospasm.
キーワード	coronary spasm angina noradrenaline severe trauma ST elevation treatment strategy
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	423
終了ページ	427
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635143
Web of Science KeyUT	001163659800004

Immunohistochemical Expression of Placental Vitamin D Receptors in Pregnancies Complicated by Early and Late-Onset Preeclampsia

JaLCDOI	10.18926/AMO/65752
フルテキストURL	77_4_415.pdf
著者	Jelcic, Dzenis\| Puzovic, Velibor\| Benzon, Benjamin\| Palada, Ivan\| Jerković, Jelena\| Vulic, Marko\|
抄録	The aim of our study was to determine whether the immunohistochemical expression of placental vitamin D receptors is altered in pregnancies complicated by preeclampsia. Vitamin D receptor expression was immunohistochemically analysed in the placentas of three groups: a control group, and early- and late-onset preeclampsia groups. Total immunohistochemical intensity staining of placentas showed that the control group had a median vitamin D receptor (VDR) expression significantly higher than the placentas of mothers with early- and late-onset preeclampsia. There was no difference among the three groups in a semiquantitative analysis of VDR staining of the stroma only. Vitamin D receptors showed lower median expression in preeclampsia-affected pregnancies, especially early-onset preeclampsia. Therefore, Vitamin D receptor expression may be an important marker for normal placentation and preeclampsia onset.
キーワード	vitamin D receptor immunohistochemistry early and late-onset preeclampsia
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	415
終了ページ	422
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635142
Web of Science KeyUT	001163659800006

Usefulness of Force-Controlled Pelvic Stress Radiograph in the Evaluation and Treatment of Fragility Fractures of the Pelvis in Geriatric Patients: A Pilot Study

JaLCDOI	10.18926/AMO/65751
フルテキストURL	77_4_407.pdf
著者	Hotta, Kensuke\| Kobayashi, Takaomi\|
抄録	This study aimed to investigate the usefulness of force-controlled pelvic stress radiographs in the evaluation and treatment of fragility fractures of the pelvis (FFP) using a functional treatment strategy. We conducted a retrospective study of 55 geriatric patients with FFP who underwent pelvic stress radiographs on admission. The differences in the sacral width, pelvic ring width, and medial femoral head width between the radiographs with and without the Sam Sling II M size were defined as Δ sacral width, Δ pelvic ring width, and Δ medial femoral head width, respectively. We used Pearson’s correlation test to assess the relationship between the degree of radiographic instability and the Johns Hopkins highest level of mobility scale (JH-HLM) at 10-days postadmission. Conventional receiver-operating-characteristic curve analysis was used to identify cases requiring surgery using the best cutoff value for radiographic instability. The JH-HLM was significantly correlated with Δ sacral width (r=−0.401, p=0.017), but not with Δ pelvic ring width (r=−0.298, p=0.080) nor with Δ medial femoral head width (r= −0.261, p=0.128). The best cutoff value of Δ sacral width in identifying surgical cases was 10.7 mm (sensitivity 75.0%, specificity 98.0%). Force-controlled pelvic stress radiographs could be helpful in assessing the need for surgery on admission.
キーワード	fragility fracture of the pelvis functional treatment strategy Sam Sling stress radiograph Johns Hopkins highest level of mobility scale
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	407
終了ページ	414
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635141
Web of Science KeyUT	001163659800001

Association of Tumor Necrosis Factor-Alpha with Psychopathology in Patients with Schizophrenia

JaLCDOI	10.18926/AMO/65750
フルテキストURL	77_4_395.pdf
著者	Pavlovic, Marko\| Babic, Dragan\| Rastovic, Pejana\| Arapovic, Jurica\| Martinac, Marko\| Jakovac, Sanja\| Barbaric, Romana\|
抄録	We investigated the relationship between serum tumor necrosis factor-alpha (TNF-α) levels and psychopathological symptoms, clinical and socio-demographic characteristics and antipsychotic therapy in individuals with schizophrenia. TNF-α levels were measured in 90 patients with schizophrenia and 90 healthy controls matched by age, gender, smoking status, and body mass index. The Positive and Negative Syndrome Scale (PANSS) was used to assess the severity of psychopathology in patients. No significant differences in TNF-α levels were detected between the patients and controls (p=0.736). TNF-α levels were not correlated with total, positive, negative, general, or composite PANSS scores (all p>0.05). A significant negative correlation was observed between TNF-α levels and the PANSS cognitive factor (ρ=−0.222, p=0.035). A hierarchical regression analysis identified the cognitive factor as a significant predictor of the TNF-α level (beta=−0.258, t=−2.257, p=0.027). There were no significant differences in TNF-α levels among patients treated with different types of antipsychotics (p=0.596). TNF-α levels correlated positively with the age of onset (ρ=0.233, p=0.027) and negatively with illness duration (ρ=−0.247, p=0.019) and antipsychotic treatment duration (ρ=−0.256, p=0.015). These results indicate that TNF-α may be involved in cognitive impairment in schizophrenia, and would be a potential clinical-state marker in schizophrenia.
キーワード	tumor necrosis factor-alpha schizophrenia psychopathology immune system
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	395
終了ページ	405
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635140
Web of Science KeyUT	001163659800010

Association between Radon Hot Spring Bathing and Health Conditions: A Cross-Sectional Study in Misasa, Japan

JaLCDOI	10.18926/AMO/65749
フルテキストURL	77_4_387.pdf
著者	Kataoka, Takahiro\| Habu, Hiroshi\| Tanaka, Ayumi\| Naoe, Shota\| Murakami, Kaito\| Fujimoto, Yuki\| Yukimine, Ryohei\| Takao, Soshi\| Mitsunobu, Fumihiro\| Yorifuji, Takashi\| Yamaoka, Kiyonori\|
抄録	No epidemiological studies have examined the health effects of daily bathing in radon hot springs. In this cross-sectional study, we investigated the associations between radon hot spring bathing and health conditions. The target population was 5,250 adults ≥ 20 years old in the town of Misasa, Japan. We collected information about the participants’ bathing habits and alleviation of a variety of disease symptoms, and their self-rated health (SRH). Unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CI) were calculated. In both the adjusted and unadjusted models of hypertension, significant associations between the > 1×/week hot spring bathing and the alleviation of hypertension symptoms were observed compared to the group whose hot spring bathing was <1×/week: adjusted model, OR 5.40 (95%CI: 1.98-14.74); unadjusted model, 3.67 (1.50-8.99) and for gastroenteritis: adjusted model, 9.18 (1.15-72.96); unadjusted model, 7.62 (1.59-36.49). Compared to the no-bathing group, higher SRH was significantly associated with both bathing < 1×/week: unadjusted model, 2.27 (1.53-3.37) and > 1×/week: adjusted model, 1.91 (1.15-3.19). These findings suggest that bathing in radon hot springs is associated with higher SRH and the alleviation of hypertension and gastroenteritis.
キーワード	radon hot spring bathing habit self-rated health cross-section study
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	387
終了ページ	394
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635139
Web of Science KeyUT	001163659800003

Disease Progression-Related Markers for Aged Non-Alcoholic Fatty Liver Disease Patients

JaLCDOI	10.18926/AMO/65748
フルテキストURL	77_4_377.pdf
著者	Morimoto, Kosaku\| Takeuchi, Yasuto\| Takaki, Akinobu\| Wada, Nozomu\| Oyama, Atsushi\| Adachi, Takuya\| Onishi, Hideki\| Shiraha, Hidenori\| Okada, Hiroyuki\|
抄録	Liver fibrosis is an important phenomenon in non-alcoholic fatty liver disease (NAFLD) progression. Standard markers reflecting liver fibrosis, including the FIB-4 index, increase with age. This study aimed to identify fibrosis progression-related markers that are diagnostically beneficial even in aged individuals. Serum levels of pro- and anti-inflammatory cytokines were measured by multiple enzyme-linked immunosorbent assay. Two standard NAFLD or fibrosis progression-related markers — the FIB-4 index and APRI score — were analyzed along with cytokine levels to define the best approach to discriminate advanced fibrosis. Ninety-eight NAFLD patients were enrolled: 59 and 39 patients with fibrosis stages 1-2 and 3-4 respectively. In addition to the FIB-4 index and APRI score, the following factors showed significant differences between stages 1-2 and stages 3-4 in a multivariate analysis: platelet counts, IP-10, and RANTES. The fibrosis stage, FIB-4, APRI, PDGF-BB, and RANTES were related to the prognosis. In aged patients, IP-10, GM-CSF, and RANTES differed between stages 1-2 and stages 3-4. FIB-4 and APRI were beneficial for their correlation with fibrosis. However, to stratify either young or elderly advanced fibrosis patients, and to identify patients likely to have a bad outcome, RANTES was the best marker.
キーワード	NAFLD NASH liver fibrosis chemokine FIB-4
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	377
終了ページ	385
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635138
Web of Science KeyUT	001163659800009

Enhanced Production of EPA-Derived Anti-Inflammatory Metabolites after Oral Administration of a Novel Self-Emulsifying Highly Purified EPA Ethyl Ester Formulation (MND-2119)

フルテキストURL	fulltext.pdf
著者	Miyoshi, Toru\| Naoe, Satoko\| Wakabayashi, Hiroyuki\| Yano, Takashi\| Mori, Takuya\| Kanda, Shingo\| Arita, Makoto\| Ito, Hiroshi\|
キーワード	Eicosapentaenoic acid MND-2119 Metablolite Inflammation
発行日	2023-12-01
出版物タイトル	Journal of Atherosclerosis and Thrombosis
巻	30巻
号	12号
出版者	Japan Atherosclerosis Society
開始ページ	1927
終了ページ	1949
ISSN	1340-3478
NCID	AA11018976
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	©2023 Japan Atherosclerosis Society
論文のバージョン	publisher
PubMed ID	37532570
DOI	10.5551/jat.64135
Web of Science KeyUT	001044716000001
関連URL	isVersionOf https://doi.org/10.5551/jat.64135