start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=細胞自己凝集化技術を用いた内皮層反転血管構造を有するユニークなin vitro血管モデルの開発 kn-title=Development of a unique tissue-engineered in vitro vascular model with endothelial layer-inverted vascular tissue structure using a cell self-aggregation technique en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HASHIMOTOShingo en-aut-sei=HASHIMOTO en-aut-mei=Shingo kn-aut-name=橋本真悟 kn-aut-sei=橋本 kn-aut-mei=真悟 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=35 end-page=45 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=This Study on “Modeling Self-Transformation” and “Gestaltkreis” in the “Craftical Formation” of Individual Creators: Understanding Creative Processes Toward the Realization of “Individually Optimized Learning” kn-title=個々の制作者の「工芸的造形」における「造形的自己変革」と「ゲシュタルトクライス」の文献研究 ―「 個別最適な学び」の実現に向けた制作者の制作過程を捉える視点の検討 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究では，造形行為の過程で制作者が経験する学びを分析し考察する視点について，特に，工芸制作に関連した文献の調査により検討することを目的とした。そのため，制作者自身の見方，感じ方，考え方と造形物を共に形成していく工芸の制作過程としての金子賢治の「工芸的造形」と，制作者が自身の変化と素材の変化を一体とした造形行為を連鎖させていく学びの過程としての橋本真之の「造形的自己変革」と，人間の「自己」が生み出されていく過程としてのヴァイツゼッカーの「ゲシュタルトクライス」について文献調査した。これにより，制作者自身の見方，感じ方，考え方と造形物を共に形成していきながら，制作者自身の変化と素材の変化が一体となって生じる造形行為の過程において，自らの「自己」を生み出し続けていく制作者の学びを分析し考察する視点をまとめた。今後は，本研究の成果を検証するため，本研究で示した視点に立つ事例研究の実施を課題とする。 en-copyright= kn-copyright= en-aut-name=OHIRAShuya en-aut-sei=OHIRA en-aut-mei=Shuya kn-aut-name=大平修也 kn-aut-sei=大平 kn-aut-mei=修也 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=工芸的造形 kn-keyword=工芸的造形 en-keyword=造形的自己変革 kn-keyword=造形的自己変革 en-keyword=ゲシュタルトクライス kn-keyword=ゲシュタルトクライス en-keyword=令和の日本型学校教育 kn-keyword=令和の日本型学校教育 en-keyword=個別最適な学び kn-keyword=個別最適な学び END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=p53搭載テロメラーゼ特異的腫瘍溶解アデノウイルスによる膵臓癌における長期抗腫瘍免疫の活性化 kn-title=Long-term activation of anti-tumor immunity in pancreatic cancer by a p53-expressing telomerase-specific oncolytic adenovirus en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HASHIMOTOMasashi en-aut-sei=HASHIMOTO en-aut-mei=Masashi kn-aut-name=橋本将志 kn-aut-sei=橋本 kn-aut-mei=将志 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=18 article-no= start-page=13296 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230905 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The Relationship between the Evaluation of Public Transport Services and Travel-Based CO2 Emissions from Private Transport Modes in Regional and Metropolitan Areas in Japan en-subtitle= kn-subtitle= en-abstract= kn-abstract=Promoting public transport use is expected to contribute to reducing CO2 emissions in the transport sector. Using Okayama City and Central Tokyo as representative case studies of regional and metropolitan areas in Japan, this study examines the impact of the evaluation of the 'hard' and 'soft' attributes of rail and bus services on the overall evaluation. This study then explores the relationship between the overall evaluation and usage frequency of rail and bus services, as well as the relationship between the usage frequency and travel-based CO2 emissions from private transport modes. Furthermore, this study investigates whether the emissions cause differences in the evaluation of the 'hard' and 'soft' attributes of public transport services. The findings suggest prioritising an improvement in 'hard' rather than 'soft' attributes in order to reduce emissions through the use of public transport in regional areas. However, in metropolitan areas, no relationship was found between the evaluation of public transport services and emissions, presumably because of the lower ownership rate of private cars that residents can use freely and the markedly higher level of rail and bus services. This study provides a methodological reference for analysing the potential to reduce travel-based emissions from private transport modes by enhancing public transport service contents. en-copyright= kn-copyright= en-aut-name=PradhanShreyas en-aut-sei=Pradhan en-aut-mei=Shreyas kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=UjiharaTakehito en-aut-sei=Ujihara en-aut-mei=Takehito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HashimotoSeiji en-aut-sei=Hashimoto en-aut-mei=Seiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= en-keyword=CO2 emissions kn-keyword=CO2 emissions en-keyword=public transport kn-keyword=public transport en-keyword=evaluation kn-keyword=evaluation en-keyword='hard' and 'soft' attributes kn-keyword='hard' and 'soft' attributes en-keyword=usage frequency kn-keyword=usage frequency en-keyword=private transport modes kn-keyword=private transport modes END start-ver=1.4 cd-journal=joma no-vol=127 cd-vols= no-issue=5 article-no= start-page=2223 end-page=2230 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230124 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Uniform Formation of a Characteristic Nanocomposite Structure of Biogenous Iron Oxide for High Rate Performance as the Anode of Lithium-Ion Batteries en-subtitle= kn-subtitle= en-abstract= kn-abstract=Recently, Fe2O3 has been considered as an alternative anode material for lithium-ion batteries (LIBs) owing to its high theoretical capacity (approximately 1000 mA h g-1), low cost, and nontoxicity. However, its rate performance remains poor relative to that of the conventional graphite anode. In this study, Fe2O3-based anodes were prepared through the annealing of biogenous Fe2O3 (L-BIOX) samples produced by an aquatic Fe-oxidizing bacterium. The effect of the annealing temperature on the performance of the synthesized Fe2O3-based material as the anode of an LIB was investigated. Electrochemical measurements revealed that the annealed L-BIOX samples at 300-700 degrees C exhibited higher rate performances than the unannealed material. Particularly, the sample annealed at 700 degrees C exhibited the highest capacity among the synthesized materials and showed a higher performance than the previously reported Fe2O3-based anodes. It exhibited a capacity of 923 mA h g-1 even at a high current density of 2 A g-1. After annealing at 700 degrees C and discharging, the synthesized biogenous material had a uniform nanocomposite structure composed of alpha-Fe2O3 nanoparticles dispersed in an amorphous matrix of Li-Si-P oxide. To form this uniform nanostructure, the solid-state diffusion resistance of the Li+ ions in the active material was reduced, which consequently improved the rate performance of the electrode. Therefore, this study provides substantial insights into the development and improvement of the performance of novel Fe2O3-based nanomaterials as the anode of LIBs. en-copyright= kn-copyright= en-aut-name=TakahashiMasakuni en-aut-sei=Takahashi en-aut-mei=Masakuni kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SakumaRyo en-aut-sei=Sakuma en-aut-mei=Ryo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HashimotoHideki en-aut-sei=Hashimoto en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=FujiiTatsuo en-aut-sei=Fujii en-aut-mei=Tatsuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TakadaJun en-aut-sei=Takada en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220922 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=アルコール依存症に対するナルメフェンの無作為化比較試験における臨床的モデレーターについて：探索的分析 kn-title=Clinical moderators of response to nalmefene in a randomized-controlled trial for alcohol dependence: An exploratory analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HASHIMOTONozomu en-aut-sei=HASHIMOTO en-aut-mei=Nozomu kn-aut-name=橋本望 kn-aut-sei=橋本 kn-aut-mei=望 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=マウスの肺移植モデルにおけるレシピエントのSPRED2がもたらす負の影響 kn-title=Negative impact of recipient SPRED2 deficiency on transplanted lung in a mouse model en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoKohei en-aut-sei=Hashimoto en-aut-mei=Kohei kn-aut-name=橋本好平 kn-aut-sei=橋本 kn-aut-mei=好平 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=34 cd-vols= no-issue= article-no= start-page=31 end-page=41 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200320 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=国語科における「話すこと・聞くこと」(小学校高学年)の学習指導 : 見える化による話し合い方略の指導 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=橋本紗希 kn-aut-sei=橋本 kn-aut-mei=紗希 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=倉敷市立連島西浦小学校 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue=22 article-no= start-page=134 end-page=143 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=『笈の小文』における西行の面影 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=橋本美香 kn-aut-sei=橋本 kn-aut-mei=美香 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院修了 END start-ver=1.4 cd-journal=joma no-vol=23 cd-vols= no-issue= article-no= start-page=33 end-page=41 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=202003 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The National Tax Tribunal System kn-title=国税不服審判所制度について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=御園生功 kn-aut-sei=御園生 kn-aut-mei=功 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=鈴木尚也 kn-aut-sei=鈴木 kn-aut-mei=尚也 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=中村和寛 kn-aut-sei=中村 kn-aut-mei=和寛 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=橋本和之 kn-aut-sei=橋本 kn-aut-mei=和之 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=広島国税不服審判所 affil-num=2 en-affil= kn-affil=広島国税不服審判所 affil-num=3 en-affil= kn-affil=広島国税不服審判所 affil-num=4 en-affil= kn-affil=広島国税不服審判所 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=地域在住の前期及び後期高齢者の食行動に影響する要因と栄養士の役割 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoMichiko en-aut-sei=Hashimoto en-aut-mei=Michiko kn-aut-name=橋本通子 kn-aut-sei=橋本 kn-aut-mei=通子 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Health Sciences, Okayama University kn-affil=岡山大学大学院保健学研究科 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue= article-no= start-page=106475 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190731 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Bipolar anodic electrochemical exfoliation of graphite powders en-subtitle= kn-subtitle= en-abstract= kn-abstract=The electrochemical exfoliation of graphite has attracted considerable attention as a method for large-scale, rapid production of graphene and graphene oxide (GO). As exfoliation typically requires direct electrical contact, and is limited by the shape and/or size of the starting graphite, treatment of small graphite particles and powders, the typical form available commercially, is extremely difficult. In this study, GO nanosheets were successfully prepared from small graphite particles and powders by a bipolar electrochemical process. Graphite samples were placed between two platinum feeder electrodes, and a constant current was applied between the feeder electrodes using dilute sulfuric acid as the electrolyte. Optical microscopy, atomic force microscopy, X-ray diffractometry, Raman spectroscopy, and X-ray photoelectron spectroscopy were employed to examine the samples obtained after electrolysis. The results obtained from these analyses confirmed that anodic electrochemical exfoliation occurs in the graphite samples, and the exfoliated samples are basically highly crystalline GO nanosheets with a low degree of oxidation (C/O = 3.6–5.3). This simple electrochemical method is extremely useful for preparing large amounts of graphene and GO from small particles of graphite. en-copyright= kn-copyright= en-aut-name=HashimotoHideki en-aut-sei=Hashimoto en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MuramatsuYusuke en-aut-sei=Muramatsu en-aut-mei=Yusuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NishinaYuta en-aut-sei=Nishina en-aut-mei=Yuta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AsohHidetaka en-aut-sei=Asoh en-aut-mei=Hidetaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Applied Chemistry, School of Advanced Engineering, Kogakuin University kn-affil= affil-num=2 en-affil=Department of Applied Chemistry, School of Advanced Engineering, Kogakuin University kn-affil= affil-num=3 en-affil=Research Core for Interdisciplinary Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Applied Chemistry, School of Advanced Engineering, Kogakuin University kn-affil= en-keyword=Graphite kn-keyword=Graphite en-keyword=Graphene kn-keyword=Graphene en-keyword=Graphene oxide kn-keyword=Graphene oxide en-keyword=Electrochemical exfoliation kn-keyword=Electrochemical exfoliation en-keyword=Anode kn-keyword=Anode en-keyword=Bipolar electrochemistry kn-keyword=Bipolar electrochemistry END start-ver=1.4 cd-journal=joma no-vol=35 cd-vols= no-issue= article-no= start-page=26 end-page=28 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=201906 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Challenge to hand-rear of the common marmoset kn-title=コモンマーモセットを育てる en-subtitle= kn-subtitle= en-abstract= kn-abstract= In mid July 2018, the common marmoset bred in Okayama University gave birth to a triplet. It is very difficult to raise three infants. We selected the most heaviest one of her siblings, and we call her “POCKE”. We brought her up on the bottle for 80 days from the birth instead of her own mother. After 81 days, she finaly weand. Now she has become attached to human, but we hope that she gets back to their original community, as a “common” marmoset. en-copyright= kn-copyright= en-aut-name=HashimotoHaruna en-aut-sei=Hashimoto en-aut-mei=Haruna kn-aut-name=橋本春菜 kn-aut-sei=橋本 kn-aut-mei=春菜 aut-affil-num=1 ORCID= affil-num=1 en-affil=Advanced Science Research Center, Okayama University kn-affil=岡山大学 自然生命科学研究支援センター END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=スメグマ菌におけるメチオニン関連遺伝子欠損株作製とその解析 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoKazuki en-aut-sei=Hashimoto en-aut-mei=Kazuki kn-aut-name=橋本和樹 kn-aut-sei=橋本 kn-aut-mei=和樹 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=484 cd-vols= no-issue= article-no= start-page=207 end-page=223 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170815 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=F-rationality of the ring of modular invariants en-subtitle= kn-subtitle= en-abstract= kn-abstract= Using the description of the Frobenius limit of modules over the ring of invariants under an action of a finite group on a polynomial ring over a field of characteristic p>0 developed by Symonds and the author, we give a characterization of the ring of invariants with a positive dual F-signature. Combining this result and Kemper's result on depths of the ring of invariants under an action of a permutation group, we give an example of an F-rational, but non-F-regular ring of invariants under the action of a finite group. en-copyright= kn-copyright= en-aut-name=HashimotoMitsuyasu en-aut-sei=Hashimoto en-aut-mei=Mitsuyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Mathematics, Okayama University kn-affil= en-keyword=F-rational kn-keyword=F-rational en-keyword=F-regular kn-keyword=F-regular en-keyword=Dual F-signature kn-keyword=Dual F-signature en-keyword=Frobenius limit kn-keyword=Frobenius limit END start-ver=1.4 cd-journal=joma no-vol=226 cd-vols= no-issue= article-no= start-page=165 end-page=203 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=201706 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Canonical and n-canonical modules of a Noetherian algebra en-subtitle= kn-subtitle= en-abstract= kn-abstract= We define canonical and -canonical modules of a module-finite algebra over a Noether commutative ring and study their basic properties. Using -canonical modules, we generalize a theorem on -syzygy by Araya and Iima which generalize a well-known theorem on syzygies by Evans and Griffith. Among others, we prove a noncommutative version of Aoyama’s theorem which states that a canonical module descends with respect to a flat local homomorphism. en-copyright= kn-copyright= en-aut-name=HashimotoMitsuyasu en-aut-sei=Hashimoto en-aut-mei=Mitsuyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Mathematics, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=305 cd-vols= no-issue= article-no= start-page=144 end-page=164 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170110 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The asymptotic behavior of Frobenius direct images of rings of invariants en-subtitle= kn-subtitle= en-abstract= kn-abstract= We define the Frobenius limit of a module over a ring of prime characteristic to be the limit of the normalized Frobenius direct images in a certain Grothendieck group. When a finite group acts on a polynomial ring, we calculate this limit for all the modules over the twisted group algebra that are free over the polynomial ring; we also calculate the Frobenius limit for the restriction of these to the ring of invariants. As an application, we generalize the description of the generalized F-signature of a ring of invariants by the second author and Nakajima to the modular case. en-copyright= kn-copyright= en-aut-name=HashimotoMitsuyasu en-aut-sei=Hashimoto en-aut-mei=Mitsuyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SymondsbPeter en-aut-sei=Symondsb en-aut-mei=Peter kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Department of Mathematics, Okayama University kn-affil= affil-num=2 en-affil=University of Manchester kn-affil= en-keyword=Frobenius direct image kn-keyword=Frobenius direct image en-keyword=Hilbert–Kunz multiplicity kn-keyword=Hilbert–Kunz multiplicity en-keyword=F-signature kn-keyword=F-signature en-keyword=Frobenius limit kn-keyword=Frobenius limit END start-ver=1.4 cd-journal=joma no-vol=45 cd-vols= no-issue=4 article-no= start-page=1509 end-page=1532 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20161007 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Equivariant class group. II. Enriched descent theorem en-subtitle= kn-subtitle= en-abstract= kn-abstract= We prove a version of Grothendieck’s descent theorem on an ‘enriched’ principal fiber bundle, a principal fiber bundle with an action of a larger group scheme. Using this, we prove the isomorphisms of the equivariant Picard and the class groups arising from such a principal fiber bundle. en-copyright= kn-copyright= en-aut-name=HashimotoMitsuyasu en-aut-sei=Hashimoto en-aut-mei=Mitsuyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Mathematics, Okayama University kn-affil= en-keyword=Class group kn-keyword=Class group en-keyword=descent theory kn-keyword=descent theory en-keyword=Picard group kn-keyword=Picard group en-keyword=principal fiber bundle kn-keyword=principal fiber bundle END start-ver=1.4 cd-journal=joma no-vol=129 cd-vols= no-issue=2 article-no= start-page=107 end-page=109 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Retroperitoneal abscess that ruptured the aorta： Invasive Klebsiella pneumoniae syndrome kn-title=Klebsiella pneumoniae を起因菌とした後腹膜膿瘍からの 炎症波及により腹部大動脈破裂に至った一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract= An 80-year-old Japanese man was admitted to our hospital in April 2016 with an acute high-grade fever and back pain. A systemic contrast-enhanced computed tomography scan disclosed a retroperitoneal abscess around his aorta. The blood culture revealed Klebsiella pneumoniae. Antibiotics (Cefotaxime 1 g i.v. q 6 hours) were administered, but the patient's symptoms worsened. The abscess then ruptured the aorta. An emergency surgical repair was done, and the patient recovered. Invasive Klebsiella pneumoniae syndrome has been detected in southeast Asia over the past two decades, and here we describe a rare case of a retroperitoneal abscess caused by Klebsiella pneumoniae that ruptured the aorta. en-copyright= kn-copyright= en-aut-name=YamazakiaKenji en-aut-sei=Yamazakia en-aut-mei=Kenji kn-aut-name=山崎賢士 kn-aut-sei=山崎 kn-aut-mei=賢士 aut-affil-num=1 ORCID= en-aut-name=SakakimaMasanori en-aut-sei=Sakakima en-aut-mei=Masanori kn-aut-name=榊間昌哲 kn-aut-sei=榊間 kn-aut-mei=昌哲 aut-affil-num=2 ORCID= en-aut-name=NagakuraYuka en-aut-sei=Nagakura en-aut-mei=Yuka kn-aut-name=長倉優花 kn-aut-sei=長倉 kn-aut-mei=優花 aut-affil-num=3 ORCID= en-aut-name=HashimotoHiroyuki en-aut-sei=Hashimoto en-aut-mei=Hiroyuki kn-aut-name=橋本紘幸 kn-aut-sei=橋本 kn-aut-mei=紘幸 aut-affil-num=4 ORCID= en-aut-name=TashiroTakeshi en-aut-sei=Tashiro en-aut-mei=Takeshi kn-aut-name=田代傑 kn-aut-sei=田代 kn-aut-mei=傑 aut-affil-num=5 ORCID= en-aut-name=MiwaMasashi en-aut-sei=Miwa en-aut-mei=Masashi kn-aut-name=三輪真史 kn-aut-sei=三輪 kn-aut-mei=真史 aut-affil-num=6 ORCID= en-aut-name=YonemuraKatsuhiko en-aut-sei=Yonemura en-aut-mei=Katsuhiko kn-aut-name=米村克彦 kn-aut-sei=米村 kn-aut-mei=克彦 aut-affil-num=7 ORCID= affil-num=1 en-affil=Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　疫学衛生学 affil-num=2 en-affil=Department of Internal Medicine, Fujinomiya City General Hospital kn-affil=富士宮市立病院　内科 affil-num=3 en-affil=Department of Internal Medicine, Fujinomiya City General Hospital kn-affil=富士宮市立病院　内科 affil-num=4 en-affil=Department of Internal Medicine, Fujinomiya City General Hospital kn-affil=富士宮市立病院　内科 affil-num=5 en-affil=Department of Internal Medicine, Fujinomiya City General Hospital kn-affil=富士宮市立病院　内科 affil-num=6 en-affil=Department of Internal Medicine, Fujinomiya City General Hospital kn-affil=富士宮市立病院　内科 affil-num=7 en-affil=Department of Internal Medicine, Fujinomiya City General Hospital kn-affil=富士宮市立病院　内科 en-keyword=invasive Klebsiella pneumoniae syndrome kn-keyword=invasive Klebsiella pneumoniae syndrome en-keyword=腹部大動脈破裂 (ruptured abdominal aorta) kn-keyword=腹部大動脈破裂 (ruptured abdominal aorta) en-keyword=後腹膜膿瘍 (retroperitoneal abscess) kn-keyword=後腹膜膿瘍 (retroperitoneal abscess) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=咀嚼能率の高い臼歯部人工歯の新しい咬合面デザイン kn-title=A new occlusal surface design for artificial posterior teeth to achieve high masticatory performance en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoYuki en-aut-sei=Hashimoto en-aut-mei=Yuki kn-aut-name=橋本有希 kn-aut-sei=橋本 kn-aut-mei=有希 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=直交配置型FIB-SEMを用いたコラーゲン細線維の三次元形態計測 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoMana en-aut-sei=Hashimoto en-aut-mei=Mana kn-aut-name=橋本真奈 kn-aut-sei=橋本 kn-aut-mei=真奈 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=175 end-page=182 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170327 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Practical Seminar for Introduction to the Teaching Profession on the Teacher Training Program at Okayama University : For Certain Fixation of Learning Contents and Upbringing of the Practical Qualities , Ability as the Teacher kn-title=全学教職課程における「教職論」の取組 : 学習内容の確実な定着と教師としての実践的な資質・能力の育成を目指して en-subtitle= kn-subtitle= en-abstract= kn-abstract=　全学教職コア・カリキュラムの入門科目に位置付けられている「教職論」の授業については，継続的にその内容や手法に関して改善が図られてきた。平成28 年度についても，過去５年間の取組の成果を踏まえながら，特に次の４つの視点から改善内容を模索し，より実践的で参加型の授業になるように工夫をした。①全学で導入された「60 分授業・4 学期制」に対応し，その利点を生かす。②ワークシートの活用により，個々の受講生が個人で思考する時間を確保する。③ペア学習・グループ学習の時間を設定し，可能な限りアクティブ・ラーニングを導入する。④様々な課題の解決を目指して学校現場で実際に行われている取組を出来るだけ多く紹介する。これらの改善により，学習意欲の向上と学習内容の確実な定着を図った。その結果，受講終了時に実施したアンケート調査では，多くの受講生から授業の意義について肯定的な評価が得られた。 en-copyright= kn-copyright= en-aut-name=KobayashiShintaro en-aut-sei=Kobayashi en-aut-mei=Shintaro kn-aut-name=小林清太郎 kn-aut-sei=小林 kn-aut-mei=清太郎 aut-affil-num=1 ORCID= en-aut-name=HashimotoTakuji en-aut-sei=Hashimoto en-aut-mei=Takuji kn-aut-name=橋本拓治 kn-aut-sei=橋本 kn-aut-mei=拓治 aut-affil-num=2 ORCID= en-aut-name=TakahataHiroshi en-aut-sei=Takahata en-aut-mei=Hiroshi kn-aut-name=髙旗浩志 kn-aut-sei=髙旗 kn-aut-mei=浩志 aut-affil-num=3 ORCID= en-aut-name=InadaShuuichi en-aut-sei=Inada en-aut-mei=Shuuichi kn-aut-name=稲田修一 kn-aut-sei=稲田 kn-aut-mei=修一 aut-affil-num=4 ORCID= en-aut-name=MishimaTomotaka en-aut-sei=Mishima en-aut-mei=Tomotaka kn-aut-name=三島知剛 kn-aut-sei=三島 kn-aut-mei=知剛 aut-affil-num=5 ORCID= en-aut-name=SodaKayoko en-aut-sei=Soda en-aut-mei=Kayoko kn-aut-name=曽田 佳代子 kn-aut-sei=曽田 kn-aut-mei= 佳代子 aut-affil-num=6 ORCID= en-aut-name=EgiEiji en-aut-sei=Egi en-aut-mei=Eiji kn-aut-name=江木英二 kn-aut-sei=江木 kn-aut-mei=英二 aut-affil-num=7 ORCID= affil-num=1 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=2 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=3 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=4 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=5 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=6 en-affil=Former Center for Teacher Education and Development, Okayama University kn-affil=元岡山大学教師教育開発センター affil-num=7 en-affil=Former Center for Teacher Education and Development, Okayama University kn-affil=元岡山大学教師教育開発センター en-keyword=60 分授業・4 学期制 (60 Minutes Class and 4 Semester System) kn-keyword=60 分授業・4 学期制 (60 Minutes Class and 4 Semester System) en-keyword=アクティブ・ラーニング (Active Learning) kn-keyword=アクティブ・ラーニング (Active Learning) en-keyword=学習内容の確実な定着 (Certain Fixation of Learning Contents) kn-keyword=学習内容の確実な定着 (Certain Fixation of Learning Contents) END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=81 end-page=90 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170327 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Practical Seminar for Teacher Profession on the Teacher Training Program at Okayama University : For the Making of Lecture to be able to Learn a Class Fourth Semester System from a Pillar Systematically for 60 Minutes kn-title=全学教職課程における「教職実践演習の取組」 : 60分授業・４学期制を柱に体系的に学べる講義づくりを目指して en-subtitle= kn-subtitle= en-abstract= kn-abstract=　岡山大学における全学教職実践演習については，平成25年度の本格実施から，7課程認定学部（独自で開講する教育学部を除く）と教師教育開発センターが協働して取り組んでいる。平成28年度から岡山大学では，国立の総合大学全学部実施としては全国初となる「60分授業・4学期制」が導入された。この教育改革では，単純に現状の講義内容をそのまま詰め込むものではなく，教育方法・指導の改善を一層進め，体系的に学べる構造にする講義づくりが求められている。そこで，最初に学生の進路状況や取得見込みの教員免許状の現状を確認した。次に，教育実践力を構成する力がバランスよく形成されているか，４年生前半期に取り組んだ教育実習と全学教職実践演習後のアンケート結果をもとにその効果を検証した。これに基づいて，平成28年度以降の「60分授業・4学期制」に対応した内容を構築した。 en-copyright= kn-copyright= en-aut-name=InadaShuuichi en-aut-sei=Inada en-aut-mei=Shuuichi kn-aut-name=稲田修一 kn-aut-sei=稲田 kn-aut-mei=修一 aut-affil-num=1 ORCID= en-aut-name=TakahataHiroshi en-aut-sei=Takahata en-aut-mei=Hiroshi kn-aut-name=髙旗浩志 kn-aut-sei=髙旗 kn-aut-mei=浩志 aut-affil-num=2 ORCID= en-aut-name=MishimaTomotaka en-aut-sei=Mishima en-aut-mei=Tomotaka kn-aut-name=三島知剛 kn-aut-sei=三島 kn-aut-mei=知剛 aut-affil-num=3 ORCID= en-aut-name=KobayashiSeitaro en-aut-sei=Kobayashi en-aut-mei=Seitaro kn-aut-name=小林清太郎 kn-aut-sei=小林 kn-aut-mei=清太郎 aut-affil-num=4 ORCID= en-aut-name=HashimotoTakuji en-aut-sei=Hashimoto en-aut-mei=Takuji kn-aut-name=橋本拓治 kn-aut-sei=橋本 kn-aut-mei=拓治 aut-affil-num=5 ORCID= en-aut-name=ImaiYasuyoshi en-aut-sei=Imai en-aut-mei=Yasuyoshi kn-aut-name=今井康好 kn-aut-sei=今井 kn-aut-mei=康好 aut-affil-num=6 ORCID= en-aut-name=KagaMasaru en-aut-sei=Kaga en-aut-mei=Masaru kn-aut-name=加賀勝 kn-aut-sei=加賀 kn-aut-mei=勝 aut-affil-num=7 ORCID= en-aut-name=YamaneFumio en-aut-sei=Yamane en-aut-mei=Fumio kn-aut-name=山根文男 kn-aut-sei=山根 kn-aut-mei=文男 aut-affil-num=8 ORCID= en-aut-name=SodaKayoko en-aut-sei=Soda en-aut-mei=Kayoko kn-aut-name=曽田佳代子 kn-aut-sei=曽田 kn-aut-mei=佳代子 aut-affil-num=9 ORCID= en-aut-name=EgiEiji en-aut-sei=Egi en-aut-mei=Eiji kn-aut-name=江木英二 kn-aut-sei=江木 kn-aut-mei=英二 aut-affil-num=10 ORCID= en-aut-name=GotoDaisuke en-aut-sei=Goto en-aut-mei=Daisuke kn-aut-name=後藤大輔 kn-aut-sei=後藤 kn-aut-mei=大輔 aut-affil-num=11 ORCID= en-aut-name=TakatsukaShigenobu en-aut-sei=Takatsuka en-aut-mei=Shigenobu kn-aut-name=髙塚成信 kn-aut-sei=髙塚 kn-aut-mei=成信 aut-affil-num=12 ORCID= affil-num=1 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=2 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=3 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=4 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=5 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=6 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター affil-num=7 en-affil=Graduate School of Education,Okayama University kn-affil=岡山大学大学院教育学研究科 affil-num=8 en-affil=Former Center for Teacher Education and Development,Okayama University kn-affil=元岡山大学教師教育開発センター affil-num=9 en-affil=Former Center for Teacher Education and Development,Okayama University kn-affil=元岡山大学教師教育開発センター affil-num=10 en-affil=Former Center for Teacher Education and Development,Okayama University kn-affil=元岡山大学教師教育開発センター affil-num=11 en-affil=Kawasaki University of Medical Welfare kn-affil=川崎医療福祉大学医療技術学部 affil-num=12 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター en-keyword=60分授業・4学期制 (60 Minute Class and 4 Semester System) kn-keyword=60分授業・4学期制 (60 Minute Class and 4 Semester System) en-keyword=体系的に学べる講義づくり (Creating Lectures that can be Learned Systematically) kn-keyword=体系的に学べる講義づくり (Creating Lectures that can be Learned Systematically) en-keyword=全学教職実践演習事前と事後の意識の変容 (Transformation of Consciousness Before and After Exercise for Teaching Practice at the University) kn-keyword=全学教職実践演習事前と事後の意識の変容 (Transformation of Consciousness Before and After Exercise for Teaching Practice at the University) en-keyword=全学教職実践演習 (Practical Seminar for Teacher Profession) kn-keyword=全学教職実践演習 (Practical Seminar for Teacher Profession) END start-ver=1.4 cd-journal=joma no-vol=59 cd-vols= no-issue=1 article-no= start-page=131 end-page=140 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=201701 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Higher-dimensional absolute versions of symmetric, Frobenius, and quasi-Frobenius algebras en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this paper, we define and discuss higher-dimensional and absolute versions of symmetric, Frobenius, and quasi-Frobenius algebras. In particular, we compare these with the relative notions defined by Scheja and Storch. We also prove the validity of codimension two-argument for modules over a coherent sheaf of algebras with a 2-canonical module, generalizing a result of the author. en-copyright= kn-copyright= en-aut-name=HashimotoMitsuyasu en-aut-sei=Hashimoto en-aut-mei=Mitsuyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Mathematics Faculty of Science, Okayama University kn-affil= en-keyword=canonical module kn-keyword=canonical module en-keyword=symmetric algebra kn-keyword=symmetric algebra en-keyword=Frobenius algebra kn-keyword=Frobenius algebra en-keyword=quasi-Frobenius algebra kn-keyword=quasi-Frobenius algebra en-keyword=n-canonical module kn-keyword=n-canonical module END start-ver=1.4 cd-journal=joma no-vol=128 cd-vols= no-issue=3 article-no= start-page=213 end-page=216 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20161201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Probable IgG4-related thyroiditis with cervical lymphadenopathy kn-title=リンパ節転移を伴う甲状腺癌を疑ったIgG4関連甲状腺炎（準確診群）の1 切除例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　We present a case of probably IgG4-related thyroiditis with lymphadenopathy. The patient was a 70-year-old Japanese female who was undergoing hemodialysis and had undergone a right hemi-thyroidectomy in 1989 due to carcinoma. In December 2010, an ultrasonography study revealed a hypoechoic small lesion in thyroid gland. When the patient was admitted to our hospital in November 2013, the lesion and regional lymph nodes had enlarged and we suspected that they were metastatic thyroid cancer. We performed a residual total thyroidectomy and regional lymph node dissection in August 2014. At that time, lymphoplasmacytic infiltration and fibrosis were observed histopathologically in thyroid tissue. Immunohistochemical studies revealed infiltrated lymphocytes and plasma cells were markedly IgG-positive, and the ratio of IgG4-positive to IgG-positive cells was over 40%. We therefore diagnosed the patient with IgG4-related thyroiditis. The cervical lymph nodes were metastases of papillary carcinoma from 25 years earlier. The patient remains well without any recurrences 33 months after the surgery. en-copyright= kn-copyright= en-aut-name=KobashiKenta en-aut-sei=Kobashi en-aut-mei=Kenta kn-aut-name=小橋研太 kn-aut-sei=小橋 kn-aut-mei=研太 aut-affil-num=1 ORCID= en-aut-name=IshiiHiroshi en-aut-sei=Ishii en-aut-mei=Hiroshi kn-aut-name=石井博 kn-aut-sei=石井 kn-aut-mei=博 aut-affil-num=2 ORCID= en-aut-name=NishiyamaKanako en-aut-sei=Nishiyama en-aut-mei=Kanako kn-aut-name=西山加那子 kn-aut-sei=西山 kn-aut-mei=加那子 aut-affil-num=3 ORCID= en-aut-name=MatsumiYuki en-aut-sei=Matsumi en-aut-mei=Yuki kn-aut-name=松三雄騎 kn-aut-sei=松三 kn-aut-mei=雄騎 aut-affil-num=4 ORCID= en-aut-name=HatanoMasahide en-aut-sei=Hatano en-aut-mei=Masahide kn-aut-name=羽田野雅英 kn-aut-sei=羽田野 kn-aut-mei=雅英 aut-affil-num=5 ORCID= en-aut-name=FujiwaraMasamitsu en-aut-sei=Fujiwara en-aut-mei=Masamitsu kn-aut-name=藤原雅光 kn-aut-sei=藤原 kn-aut-mei=雅光 aut-affil-num=6 ORCID= en-aut-name=KurokawaTatsuo en-aut-sei=Kurokawa en-aut-mei=Tatsuo kn-aut-name=黒河達雄 kn-aut-sei=黒河 kn-aut-mei=達雄 aut-affil-num=7 ORCID= en-aut-name=TsunemitsuKensuke en-aut-sei=Tsunemitsu en-aut-mei=Kensuke kn-aut-name=常光謙輔 kn-aut-sei=常光 kn-aut-mei=謙輔 aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Surgery, Saiseikai Saijo Hospital kn-affil=済生会西条病院　外科 affil-num=2 en-affil=Department of Surgery, Saiseikai Saijo Hospital kn-affil=済生会西条病院　外科 affil-num=3 en-affil=Breast Center, Ehime University Hospital kn-affil=愛媛大学医学部附属病院　乳腺センター affil-num=4 en-affil=Department of Surgery, Saiseikai Saijo Hospital kn-affil=済生会西条病院　外科 affil-num=5 en-affil=Department of Surgery, Saiseikai Saijo Hospital kn-affil=済生会西条病院　外科 affil-num=6 en-affil=Department of Surgery, Imabariishikaishimin Hospital kn-affil=今治医師会市民病院　外科 affil-num=7 en-affil=Department of Surgery, Saiseikai Saijo Hospital kn-affil=済生会西条病院　外科 affil-num=8 en-affil=Department of Surgery, Saiseikai Saijo Hospital kn-affil=済生会西条病院　外科 en-keyword=IgG4 関連甲状腺炎（IgG4-related thyroiditis） kn-keyword=IgG4 関連甲状腺炎（IgG4-related thyroiditis） en-keyword=橋本病（Hashimoto’s thyroiditis） kn-keyword=橋本病（Hashimoto’s thyroiditis） en-keyword=転移性リンパ節腫瘍（metastatic lymph node tumor） kn-keyword=転移性リンパ節腫瘍（metastatic lymph node tumor） en-keyword=慢性腎不全（chronic renal failure） kn-keyword=慢性腎不全（chronic renal failure） END start-ver=1.4 cd-journal=joma no-vol=459 cd-vols= no-issue= article-no= start-page=76 end-page=108 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Equivariant class group. I. Finite generation of the Picard and the class groups of an invariant subring en-subtitle= kn-subtitle= en-abstract= kn-abstract=The purpose of this paper is to define equivariant class group of a locally Krull scheme (that is, a scheme which is locally a prime spectrum of a Krull domain) with an action of a flat group scheme, study its basic properties, and apply it to prove the finite generation of the class group of an invariant subring. In particular, we prove the following. Let k be a field, G a smooth k-group scheme of finite type, and X a quasi-compact quasi-separated locally Krull G-scheme. Assume that there is a k-scheme Z of finite type and a dominant k -morphism Z→XZ→X. Let φ:X→Yφ:X→Y be a G -invariant morphism such that OY→(φ⁎OX)GOY→(φ⁎OX)G is an isomorphism. Then Y is locally Krull. If, moreover, Cl(X)Cl(X) is finitely generated, then Cl(G,X)Cl(G,X) and Cl(Y)Cl(Y) are also finitely generated, where Cl(G,X)Cl(G,X) is the equivariant class group. In fact, Cl(Y)Cl(Y) is a subquotient of Cl(G,X)Cl(G,X). For actions of connected group schemes on affine schemes, there are similar results of Magid and Waterhouse, but our result also holds for disconnected G. The proof depends on a similar result on (equivariant) Picard groups. en-copyright= kn-copyright= en-aut-name=HashimotoMitsuyasu en-aut-sei=Hashimoto en-aut-mei=Mitsuyasu kn-aut-name=橋本光靖 kn-aut-sei=橋本 kn-aut-mei=光靖 aut-affil-num=1 ORCID= affil-num=1 en-affil=Okayama University kn-affil=岡山大学大学院自然科学研究科 en-keyword=Invariant theory kn-keyword=Invariant theory en-keyword=Class group kn-keyword=Class group en-keyword=Picard group kn-keyword=Picard group en-keyword=Krull ring kn-keyword=Krull ring END start-ver=1.4 cd-journal=joma no-vol=40 cd-vols= no-issue=3 article-no= start-page=527 end-page=534 dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=201509 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Classification of the Linearly Reductive Finite Subgroup Schemes of SL2 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We classify the linearly reductive finite subgroup schemes G of SL2=SL(V) over an algebraically closed field k of positive characteristic, up to conjugation. As a corollary, we prove that such G is in one-to-one correspondence with an isomorphism class of two-dimensional F-rational Gorenstein complete local rings with the coefficient field k by the correspondence G↦((SymV)G) ˆ. en-copyright= kn-copyright= en-aut-name=HashimotoMitsuyasu en-aut-sei=Hashimoto en-aut-mei=Mitsuyasu kn-aut-name=橋本光靖 kn-aut-sei=橋本 kn-aut-mei=光靖 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Mathematics, Okayama University kn-affil=岡山大学大学院自然科学研究科 en-keyword=Group scheme kn-keyword=Group scheme en-keyword=Kleinian singularity kn-keyword=Kleinian singularity en-keyword=Invariant theory kn-keyword=Invariant theory END start-ver=1.4 cd-journal=joma no-vol=161 cd-vols= no-issue= article-no= start-page=69 end-page=75 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study of the Post-War Practice of teaching Japanese in Junior-high-school kn-title=戦後国語教育実践についての研究 ― 橋本武の灘中学における『銀の匙』（中勘助）の指導実践を中心に ― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SugaharaMinoru en-aut-sei=Sugahara en-aut-mei=Minoru kn-aut-name=菅原稔 kn-aut-sei=菅原 kn-aut-mei=稔 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院教育学研究科 en-keyword=橋本武 kn-keyword=橋本武 en-keyword=灘中学校 kn-keyword=灘中学校 en-keyword=スローリーディング kn-keyword=スローリーディング en-keyword=中勘助 kn-keyword=中勘助 en-keyword=『銀の匙』 kn-keyword=『銀の匙』 END start-ver=1.4 cd-journal=joma no-vol=5 cd-vols= no-issue= article-no= start-page=93 end-page=100 dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20150306 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study of developing a teaching program for a voter education from an elementary school to a high school　Based on developing a tentative lesson plan of an elementary social studies in order to teach about vote kn-title=小中高一貫有権者教育プログラム開発の方法（１）:「選挙」をテーマとする小学校社会科の単元の開発を通して en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究は，市民社会に寄与し得る有権者の育成を目指し，児童・生徒の発達段階に応じた有権者教育のあり方 を追究して，小学校から高等学校までの12 年間を一貫する原理にもとづいた有権者教育プログラム開発のため の原理と方法を解明しようとするものである。そのために，第一に，子どもたちの政治に対する認識調査を行い， 子どもたちが政治的な概念についてどのような認識を持っており，それを教育によってどの程度まで変容させる ことができるかを明らかにした。そして，第二に，その調査の結果と従来の政治教育研究の成果をふまえて，有 権者教育のための小中高一貫カリキュラム・フレームワークを提示した。それに基づいて，第三に，具体的な単 元開発を行った。単元は，「選挙」，「議会」，「税金」という政治学の基本的概念をテーマとして取り上げて開発 したが，本稿では「選挙」概念をテーマとして開発した小学校社会科の単元を紹介する。 en-copyright= kn-copyright= en-aut-name=KuwabaraToshinori en-aut-sei=Kuwabara en-aut-mei=Toshinori kn-aut-name=桑原敏典 kn-aut-sei=桑原 kn-aut-mei=敏典 aut-affil-num=1 ORCID= en-aut-name=KudoBunzo en-aut-sei=Kudo en-aut-mei=Bunzo kn-aut-name=工藤文三 kn-aut-sei=工藤 kn-aut-mei=文三 aut-affil-num=2 ORCID= en-aut-name=TanahashiKenji en-aut-sei=Tanahashi en-aut-mei=Kenji kn-aut-name=棚橋健治 kn-aut-sei=棚橋 kn-aut-mei=健治 aut-affil-num=3 ORCID= en-aut-name=YatabeReio en-aut-sei=Yatabe en-aut-mei=Reio kn-aut-name=谷田部玲生 kn-aut-sei=谷田部 kn-aut-mei=玲生 aut-affil-num=4 ORCID= en-aut-name=KoyamaShigeki en-aut-sei=Koyama en-aut-mei=Shigeki kn-aut-name=小山茂喜 kn-aut-sei=小山 kn-aut-mei=茂喜 aut-affil-num=5 ORCID= en-aut-name=YoshimuraKotaro en-aut-sei=Yoshimura en-aut-mei=Kotaro kn-aut-name=吉村功太郎 kn-aut-sei=吉村 kn-aut-mei=功太郎 aut-affil-num=6 ORCID= en-aut-name=OshiharaSusumu en-aut-sei=Oshihara en-aut-mei=Susumu kn-aut-name=鴛原進 kn-aut-sei=鴛原 kn-aut-mei=進 aut-affil-num=7 ORCID= en-aut-name=NagataTadamichi en-aut-sei=Nagata en-aut-mei=Tadamichi kn-aut-name=永田忠道 kn-aut-sei=永田 kn-aut-mei=忠道 aut-affil-num=8 ORCID= en-aut-name=HashimotoYasuhiro en-aut-sei=Hashimoto en-aut-mei=Yasuhiro kn-aut-name=橋本康弘 kn-aut-sei=橋本 kn-aut-mei=康弘 aut-affil-num=9 ORCID= en-aut-name=WatanabeTatsuya en-aut-sei=Watanabe en-aut-mei=Tatsuya kn-aut-name=渡部竜也 kn-aut-sei=渡部 kn-aut-mei=竜也 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院教育学研究科 affil-num=2 en-affil= kn-affil=帝塚山学院大学人間科学部 affil-num=3 en-affil= kn-affil=広島大学大学院教育学研究科 affil-num=4 en-affil= kn-affil=桐蔭横浜大学法学部 affil-num=5 en-affil= kn-affil=信州大学全学教育機構 affil-num=6 en-affil= kn-affil=宮崎大学大学院教育学研究科 affil-num=7 en-affil= kn-affil=愛媛大学教育学部 affil-num=8 en-affil= kn-affil=広島大学大学院教育学研究科 affil-num=9 en-affil= kn-affil=福井大学教育地域科学部 affil-num=10 en-affil= kn-affil=東京学芸大学教育学部 en-keyword=有権者教育 kn-keyword=有権者教育 en-keyword=小中高一貫 kn-keyword=小中高一貫 en-keyword=カリキュラム・フレームワーク kn-keyword=カリキュラム・フレームワーク en-keyword=小学校社会科 kn-keyword=小学校社会科 en-keyword=単元開発 kn-keyword=単元開発 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue=5 article-no= start-page=295 end-page=302 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20141015 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Image Recognition Method to Measure Angular Velocity from Movement of a Back of Hand for Safety Education kn-title=安全教育のため手の甲によるバルブ速度測定画像認識法 en-subtitle= kn-subtitle= en-abstract=　The realization of training of virtual reality is expected to prevent the accidents caused by human factor. The benefits of training in virtual environment is a realization of training in a simulated real environment. However, there is a problem that a trainee cannot train in the simulated real environment because there is no user interface （UI） to transmit the valve operations which is basic manipulation in the industrial plant to the training system. In this study, we propose an image recognition method for developing a valve manipulation UI which aims to realize the training of valve opening manipulation in virtual environment. The method to measure the angular velocity of the circular handle of a valve utilizes the optical natural feature points obtained from the hand turning the handle. The advantage of our valve manipulation UI is that the UI can construct easily by popular products such as PC, web camera. Our method was revealed to be able to be applied to the UI of training system for worker to train valve operating manipulation which assumed fire risk because it can measure the velocity of 22.5～90 deg/s. kn-abstract=　人的要因の事故を防止する為，仮想現実感を利用した訓練の実現が期待されている．仮想環境での訓練の利点は実環境に近い環境で訓練できる点にある．しかし，プラント内で基本操作であるバルブの操作をシステムへ伝えるユーザ・インタフェース（UIと省略）は現在なく，実環境に即した訓練ができない問題がある． 　そこで本研究では，仮想環境におけるバルブ開操作訓練を実現するバルブ操作UI開発のため，バルブの丸ハンドルの回転速度を測定する画像認識手法を提案する．本手法はバルブの丸ハンドルを回す手から取得した光学的自然特徴点を利用する．本バルブ開操作UIはPC，Webカメラといった一般的な製品を用い平易に実現できる利点がある． 　本手法は，評価実験で22.5-90deg/sを測定できる事を確認できたため，発火危険を想定したバルブ操作訓練のためのUIに適用できる事が明らかとなった． en-copyright= kn-copyright= en-aut-name=MINOWAHirotsugu en-aut-sei=MINOWA en-aut-mei=Hirotsugu kn-aut-name=箕輪弘嗣 kn-aut-sei=箕輪 kn-aut-mei=弘嗣 aut-affil-num=1 ORCID= en-aut-name=MUNESAWAYoshiomi en-aut-sei=MUNESAWA en-aut-mei=Yoshiomi kn-aut-name=宗澤良臣 kn-aut-sei=宗澤 kn-aut-mei=良臣 aut-affil-num=2 ORCID= en-aut-name=HASHIMOTOKohei en-aut-sei=HASHIMOTO en-aut-mei=Kohei kn-aut-name=橋本康平 kn-aut-sei=橋本 kn-aut-mei=康平 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学自然科学研究科 affil-num=2 en-affil= kn-affil=広島工業大学 工学部 機械システム工学科 affil-num=3 en-affil= kn-affil=（株）今仙電機製作所 en-keyword=画像認識 kn-keyword=画像認識 en-keyword=仮想現実感 kn-keyword=仮想現実感 en-keyword=ユーザ・インタフェース kn-keyword=ユーザ・インタフェース en-keyword=バルブ kn-keyword=バルブ en-keyword=プラント安全 kn-keyword=プラント安全 END start-ver=1.4 cd-journal=joma no-vol=125 cd-vols= no-issue=3 article-no= start-page=239 end-page=242 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20131202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of appendiceal diverticulum resected by laparoscopic surgery with preoperative diagnosis of appendiceal tumor kn-title=虫垂腫瘍と術前診断し腹腔鏡下手術を行った虫垂仮性憩室症の１例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　Appendiceal diverticulum is rare. We encountered a case of appendiceal diverticulum with chronic appendicitis. A 56-year-old man presented to our hospital with right lower abdominal pain. An abdominal computed tomography (CT) scan showed swelling of the appendix body and the wall thickness of the base of the appendix. Due to the possibility of appendiceal tumor, we performed a laparoscopy-assisted ileocecal resection with lymph node dissection. The appendix had a diverticulum with chronic inflammation, but it did not have a neoplastic lesion. en-copyright= kn-copyright= en-aut-name=NinomiyaTakayuki en-aut-sei=Ninomiya en-aut-mei=Takayuki kn-aut-name=二宮卓之 kn-aut-sei=二宮 kn-aut-mei=卓之 aut-affil-num=1 ORCID= en-aut-name=OjimaYasutomo en-aut-sei=Ojima en-aut-mei=Yasutomo kn-aut-name=小島康知 kn-aut-sei=小島 kn-aut-mei=康知 aut-affil-num=2 ORCID= en-aut-name=HaranoMasao en-aut-sei=Harano en-aut-mei=Masao kn-aut-name=原野雅生 kn-aut-sei=原野 kn-aut-mei=雅生 aut-affil-num=3 ORCID= en-aut-name=OhnoSatoshi en-aut-sei=Ohno en-aut-mei=Satoshi kn-aut-name=大野聡 kn-aut-sei=大野 kn-aut-mei=聡 aut-affil-num=4 ORCID= en-aut-name=ShiozakiShigehiro en-aut-sei=Shiozaki en-aut-mei=Shigehiro kn-aut-name=塩崎滋弘 kn-aut-sei=塩崎 kn-aut-mei=滋弘 aut-affil-num=5 ORCID= en-aut-name=NinomiyaMotoki en-aut-sei=Ninomiya en-aut-mei=Motoki kn-aut-name=二宮基樹 kn-aut-sei=二宮 kn-aut-mei=基樹 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=2 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=3 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=4 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=5 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=6 en-affil= kn-affil=広島市立広島市民病院　外科 en-keyword=虫垂憩室症（appendiceal diverculum） kn-keyword=虫垂憩室症（appendiceal diverculum） en-keyword=腹腔鏡手術（laparoscopic surgery） kn-keyword=腹腔鏡手術（laparoscopic surgery） en-keyword=虫垂腫瘍（appendiceal tumor） kn-keyword=虫垂腫瘍（appendiceal tumor） END start-ver=1.4 cd-journal=joma no-vol=125 cd-vols= no-issue=3 article-no= start-page=195 end-page=199 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20131202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Genetically engineered oncolytic adenovirus induces autophagic cell death through an E2F1-microRNA-7-epidermal growth factor receptor axis kn-title=腫瘍融解アデノウイルスによるE2F1-マイクロRNA-7-EGFR経路を介したオートファジー細胞死の誘導分子機構 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TazawaHiroshi en-aut-sei=Tazawa en-aut-mei=Hiroshi kn-aut-name=田澤大 kn-aut-sei=田澤 kn-aut-mei=大 aut-affil-num=1 ORCID= en-aut-name=YanoSyuya en-aut-sei=Yano en-aut-mei=Syuya kn-aut-name=矢野修也 kn-aut-sei=矢野 kn-aut-mei=修也 aut-affil-num=2 ORCID= en-aut-name=YoshidaRyosuke en-aut-sei=Yoshida en-aut-mei=Ryosuke kn-aut-name=吉田亮介 kn-aut-sei=吉田 kn-aut-mei=亮介 aut-affil-num=3 ORCID= en-aut-name=YamasakiYasumoto en-aut-sei=Yamasaki en-aut-mei=Yasumoto kn-aut-name=山崎泰源 kn-aut-sei=山崎 kn-aut-mei=泰源 aut-affil-num=4 ORCID= en-aut-name=SasakiTsuyoshi en-aut-sei=Sasaki en-aut-mei=Tsuyoshi kn-aut-name=佐々木剛 kn-aut-sei=佐々木 kn-aut-mei=剛 aut-affil-num=5 ORCID= en-aut-name=HashimotoYuuri en-aut-sei=Hashimoto en-aut-mei=Yuuri kn-aut-name=橋本悠里 kn-aut-sei=橋本 kn-aut-mei=悠里 aut-affil-num=6 ORCID= en-aut-name=KurodaShinji en-aut-sei=Kuroda en-aut-mei=Shinji kn-aut-name=黒田新士 kn-aut-sei=黒田 kn-aut-mei=新士 aut-affil-num=7 ORCID= en-aut-name=OuchiMasaaki en-aut-sei=Ouchi en-aut-mei=Masaaki kn-aut-name=大内正明 kn-aut-sei=大内 kn-aut-mei=正明 aut-affil-num=8 ORCID= en-aut-name=OnishiTeppei en-aut-sei=Onishi en-aut-mei=Teppei kn-aut-name=大西哲平 kn-aut-sei=大西 kn-aut-mei=哲平 aut-affil-num=9 ORCID= en-aut-name=UnoFutoshi en-aut-sei=Uno en-aut-mei=Futoshi kn-aut-name=宇野太 kn-aut-sei=宇野 kn-aut-mei=太 aut-affil-num=10 ORCID= en-aut-name=KagawaSyunsuke en-aut-sei=Kagawa en-aut-mei=Syunsuke kn-aut-name=香川俊輔 kn-aut-sei=香川 kn-aut-mei=俊輔 aut-affil-num=11 ORCID= en-aut-name=UrataYasuo en-aut-sei=Urata en-aut-mei=Yasuo kn-aut-name=浦田泰生 kn-aut-sei=浦田 kn-aut-mei=泰生 aut-affil-num=12 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name=藤原俊義 kn-aut-sei=藤原 kn-aut-mei=俊義 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院　新医療研究開発センター affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=7 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=8 en-affil= kn-affil=オンコリスバイオファーマ株式会社 affil-num=9 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=10 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=11 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=12 en-affil= kn-affil=オンコリスバイオファーマ株式会社 affil-num=13 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 en-keyword=アデノウイルス kn-keyword=アデノウイルス en-keyword=テロメラーゼ kn-keyword=テロメラーゼ en-keyword=マイクロRNA kn-keyword=マイクロRNA en-keyword=オートファジー kn-keyword=オートファジー en-keyword=EGFR kn-keyword=EGFR END start-ver=1.4 cd-journal=joma no-vol=153 cd-vols= no-issue= article-no= start-page=59 end-page=69 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130725 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Consideration of a Choral Warm-up II ―from a Viewpoint of “Physical Relaxation”― kn-title=合唱のウォームアップに関する考察(2)身体のリラックスの視点から en-subtitle= kn-subtitle= en-abstract= kn-abstract=合唱のウォームアップについて，合唱指導者の取り組みや合唱団の事例を通して，身体の リラックスの視点から考察した。野口体操や体ほぐしを取り入れた合唱指導者渡辺，岩崎， 橋本ら３者は，身体の柔軟性が良好な発声を導くという考えに基づいていることを示してお り，また，岩崎，橋本は，心理的柔軟性もその条件に付加していることが明らかになった。 次に，合唱団の実践例から，全体的に，身体的な観点からは「呼吸」と「姿勢」を大切にし た指導が行われ，上肢部分のストレッチに重点が置かれていることがわかった。他方，心理 的観点からは仲間との触れ合いを取り入れて心をほぐすなどの工夫が見られた。さらに，呼 吸と運動（動き）を同時に行う，合唱団員の年齢に応じた活動を取り入れるなどの工夫も見 られ，これらの活動が，息が自然に声につながるための手立てとなる示唆を得た。 en-copyright= kn-copyright= en-aut-name=MushiakiMasako en-aut-sei=Mushiaki en-aut-mei=Masako kn-aut-name=虫明眞砂子 kn-aut-sei=虫明 kn-aut-mei=眞砂子 aut-affil-num=1 ORCID= en-aut-name=KuroiKaori en-aut-sei=Kuroi en-aut-mei=Kaori kn-aut-name=黒井かおり kn-aut-sei=黒井 kn-aut-mei=かおり aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil= affil-num=2 en-affil= kn-affil= en-keyword=体ほぐし kn-keyword=体ほぐし en-keyword=リラックス kn-keyword=リラックス en-keyword=呼吸 kn-keyword=呼吸 en-keyword=合唱 kn-keyword=合唱 en-keyword=ウォームアップ kn-keyword=ウォームアップ END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130321 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=鹿田遺跡 7 ―第10次調査、第18次調査B・C地点― (医学部共同溝・岡山大学病院中央診療棟建設に伴う発掘調査) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=野崎貴博 kn-aut-sei=野崎 kn-aut-mei=貴博 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=光本順 kn-aut-sei=光本 kn-aut-mei=順 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=岩崎志保 kn-aut-sei=岩崎 kn-aut-mei=志保 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=能城修一 kn-aut-sei=能城 kn-aut-mei=修一 aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=橋本裕子 kn-aut-sei=橋本 kn-aut-mei=裕子 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil= affil-num=4 en-affil= kn-affil= affil-num=5 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=125 cd-vols= no-issue=1 article-no= start-page=29 end-page=33 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Mesalazine suppositories and their clinical application kn-title=メサラジン坐薬調製の工夫と臨床経験 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Ulcerative proctitis (UP) is a prevalent condition associated with increased morbidity, and topical mesalazine (5-aminosalicylic acid [5-ASA]) is known to inhibit the inflammatory processes in UP. We successfully devised mesalazine suppositories, in which 250mg mesalazine was equally distributed and remained stable for at least 2 weeks. We evaluated the effect of using mesalazine suppositories twice a day (BID) on two UP patients. The results demonstrated that mesalazine suppositories were efficacious, well tolerated and safe for the long-term maintenance of UP remission. en-copyright= kn-copyright= en-aut-name=FunagakureKeiko en-aut-sei=Funagakure en-aut-mei=Keiko kn-aut-name=船隠恵子 kn-aut-sei=船隠 kn-aut-mei=恵子 aut-affil-num=1 ORCID= en-aut-name=HoritaSyuzi en-aut-sei=Horita en-aut-mei=Syuzi kn-aut-name=堀田修次 kn-aut-sei=堀田 kn-aut-mei=修次 aut-affil-num=2 ORCID= en-aut-name=HamaokaTerutaka en-aut-sei=Hamaoka en-aut-mei=Terutaka kn-aut-name=濱岡照隆 kn-aut-sei=濱岡 kn-aut-mei=照隆 aut-affil-num=3 ORCID= en-aut-name=TasakaTakeshi en-aut-sei=Tasaka en-aut-mei=Takeshi kn-aut-name=田阪武志 kn-aut-sei=田阪 kn-aut-mei=武志 aut-affil-num=4 ORCID= en-aut-name=TatibanaHiroshi en-aut-sei=Tatibana en-aut-mei=Hiroshi kn-aut-name=立花広志 kn-aut-sei=立花 kn-aut-mei=広志 aut-affil-num=5 ORCID= en-aut-name=MurakamiTakako en-aut-sei=Murakami en-aut-mei=Takako kn-aut-name=村上敬子 kn-aut-sei=村上 kn-aut-mei=敬子 aut-affil-num=6 ORCID= en-aut-name=ToyokawaTatuya en-aut-sei=Toyokawa en-aut-mei=Tatuya kn-aut-name=豊川達也 kn-aut-sei=豊川 kn-aut-mei=達也 aut-affil-num=7 ORCID= en-aut-name=SatoEiji en-aut-sei=Sato en-aut-mei=Eiji kn-aut-name=佐藤英治 kn-aut-sei=佐藤 kn-aut-mei=英治 aut-affil-num=8 ORCID= en-aut-name=TomodaJun en-aut-sei=Tomoda en-aut-mei=Jun kn-aut-name=友田純 kn-aut-sei=友田 kn-aut-mei=純 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=国立病院機構福山医療センター　薬剤科 affil-num=2 en-affil= kn-affil=国立病院機構福山医療センター　薬剤科 affil-num=3 en-affil= kn-affil=国立病院機構福山医療センター　薬剤科 affil-num=4 en-affil= kn-affil=国立病院機構福山医療センター　薬剤科 affil-num=5 en-affil= kn-affil=国立病院機構福山医療センター　薬剤科 affil-num=6 en-affil= kn-affil=国立病院機構福山医療センター　内科 affil-num=7 en-affil= kn-affil=国立病院機構福山医療センター　内科 affil-num=8 en-affil= kn-affil=福山大学薬学部 affil-num=9 en-affil= kn-affil=国立病院機構福山医療センター　内科 en-keyword=メサラジン坐薬（mesalazine suppositories） kn-keyword=メサラジン坐薬（mesalazine suppositories） en-keyword=潰瘍性大腸炎直腸型（ulcerative proctitis） kn-keyword=潰瘍性大腸炎直腸型（ulcerative proctitis） END start-ver=1.4 cd-journal=joma no-vol=125 cd-vols= no-issue=1 article-no= start-page=9 end-page=12 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Telomerase-specific virotherapy targeting lymph node micrometastasis of human cancer kn-title=癌微小リンパ節転移を標的とするテロメラーゼ特異的制限増殖型ウイルス製剤の開発 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KojimaToru en-aut-sei=Kojima en-aut-mei=Toru kn-aut-name=児島亨 kn-aut-sei=児島 kn-aut-mei=亨 aut-affil-num=1 ORCID= en-aut-name=WatanabeYuichi en-aut-sei=Watanabe en-aut-mei=Yuichi kn-aut-name=渡邉雄一 kn-aut-sei=渡邉 kn-aut-mei=雄一 aut-affil-num=2 ORCID= en-aut-name=HashimotoYuuri en-aut-sei=Hashimoto en-aut-mei=Yuuri kn-aut-name=橋本悠里 kn-aut-sei=橋本 kn-aut-mei=悠里 aut-affil-num=3 ORCID= en-aut-name=KurodaShinji en-aut-sei=Kuroda en-aut-mei=Shinji kn-aut-name=黒田新士 kn-aut-sei=黒田 kn-aut-mei=新士 aut-affil-num=4 ORCID= en-aut-name=YamasakiYasumoto en-aut-sei=Yamasaki en-aut-mei=Yasumoto kn-aut-name=山崎泰源 kn-aut-sei=山崎 kn-aut-mei=泰源 aut-affil-num=5 ORCID= en-aut-name=YanoShuya en-aut-sei=Yano en-aut-mei=Shuya kn-aut-name=矢野修也 kn-aut-sei=矢野 kn-aut-mei=修也 aut-affil-num=6 ORCID= en-aut-name=TazawaHiroshi en-aut-sei=Tazawa en-aut-mei=Hiroshi kn-aut-name=田澤大 kn-aut-sei=田澤 kn-aut-mei=大 aut-affil-num=7 ORCID= en-aut-name=UnoFutoshi en-aut-sei=Uno en-aut-mei=Futoshi kn-aut-name=宇野太 kn-aut-sei=宇野 kn-aut-mei=太 aut-affil-num=8 ORCID= en-aut-name=KagawaShunsuke en-aut-sei=Kagawa en-aut-mei=Shunsuke kn-aut-name=香川俊輔 kn-aut-sei=香川 kn-aut-mei=俊輔 aut-affil-num=9 ORCID= en-aut-name=TanakaNoriaki en-aut-sei=Tanaka en-aut-mei=Noriaki kn-aut-name=田中紀章 kn-aut-sei=田中 kn-aut-mei=紀章 aut-affil-num=10 ORCID= en-aut-name=UrataYasuo en-aut-sei=Urata en-aut-mei=Yasuo kn-aut-name=浦田泰生 kn-aut-sei=浦田 kn-aut-mei=泰生 aut-affil-num=11 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name=藤原俊義 kn-aut-sei=藤原 kn-aut-mei=俊義 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=2 en-affil= kn-affil=オンコリスバイオファーマ affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=7 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=8 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=9 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=10 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=11 en-affil= kn-affil=オンコリスバイオファーマ affil-num=12 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 en-keyword=telomerase kn-keyword=telomerase en-keyword=oncolytic adenovirus kn-keyword=oncolytic adenovirus en-keyword=lymph node metastasis kn-keyword=lymph node metastasis en-keyword=orthotopic colorectal cancer model kn-keyword=orthotopic colorectal cancer model en-keyword=Alu sequence kn-keyword=Alu sequence END start-ver=1.4 cd-journal=joma no-vol=34 cd-vols= no-issue= article-no= start-page=8 end-page=13 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=201212 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=新しい太陽光発電システムの現状と今後 (集光型太陽光発電システム) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=橋本潤 kn-aut-sei=橋本 kn-aut-mei=潤 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120927 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=腫瘍の低酸素環境においてhTERTプロモーターは腫瘍融解アデノウイルスの抗腫瘍活性を増強する kn-title=The hTERT Promoter Enhances the Antitumor Activity of an Oncolytic Adenovirus under a Hypoxic Microenvironment en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoYuri en-aut-sei=Hashimoto en-aut-mei=Yuri kn-aut-name=橋本悠里 kn-aut-sei=橋本 kn-aut-mei=悠里 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=49 cd-vols= no-issue=4 article-no= start-page=1118 end-page=1125 dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=201104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Exfoliated graphene sheets decorated with metal / metal oxide nanoparticles: simple preparation from cation exchanged graphite oxide en-subtitle= kn-subtitle= en-abstract= kn-abstract=We produced carbon hybrid materials of graphene sheets decorated with metal or metal oxide nanoparticles of gold, silver, copper, cobalt, or nickel from cation exchanged graphite oxide. Measurements using powder X-ray diffraction, transmission electron microscopy, and X-ray absorption spectra revealed that the Au and Ag in the materials (Au-Gr and Ag-Gr) existed on graphene sheets as metal nanoparticles, whereas Cu and Co in the materials (Cu-Gr and Co-Gr) existed as a metal oxide. Most Ni particles in Ni-Gr were metal, but the surfaces of large particles were partly oxidized, producing a core-shell structure. The Ag-Gr sample showed a catalytic activity for the oxygen reduction reaction in 1.0 M KOH aq. under an oxygen atmosphere. Ag-Gr is superior as a cathode in alkaline fuel cells, which should not be disturbed by the methanol cross-over problem from the anode. We established an effective approach to prepare a series of graphene-nanoparticle composite materials using heat treatment. en-copyright= kn-copyright= en-aut-name=GotohKazuma en-aut-sei=Gotoh en-aut-mei=Kazuma kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KinumotoTaro en-aut-sei=Kinumoto en-aut-mei=Taro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FujiiEiji en-aut-sei=Fujii en-aut-mei=Eiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamamotoAki en-aut-sei=Yamamoto en-aut-mei=Aki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HashimotoHideki en-aut-sei=Hashimoto en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OhkuboTakahiro en-aut-sei=Ohkubo en-aut-mei=Takahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ItadaniAtsushi en-aut-sei=Itadani en-aut-mei=Atsushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KurodaYasushige en-aut-sei=Kuroda en-aut-mei=Yasushige kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=IshidaHiroyuki en-aut-sei=Ishida en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=Okayama Univ affil-num=2 en-affil= kn-affil=Oita Univ affil-num=3 en-affil= kn-affil=Ind Technol Ctr affil-num=4 en-affil= kn-affil=Okayama Univ affil-num=5 en-affil= kn-affil=Okayama Univ affil-num=6 en-affil= kn-affil=Okayama Univ affil-num=7 en-affil= kn-affil=Okayama Univ affil-num=8 en-affil= kn-affil=Okayama Univ affil-num=9 en-affil= kn-affil=Okayama Univ END start-ver=1.4 cd-journal=joma no-vol=124 cd-vols= no-issue=2 article-no= start-page=105 end-page=110 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Preclinical evaluation of telomerase-specific oncolytic virotherapy for human bone and soft tissue sarcomas kn-title=テロメラーゼ依存性腫瘍融解ウイルス療法の骨・軟部肉腫に対する前臨床的検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=骨・軟部肉腫は, 一部に治療抵抗性で予後の悪い症例が存在するため, 新たな治療法の確立が重要な課題である.　我々は, 5型アデノウイルスを基本骨格として, テロメラーゼ活性に依存して増殖する腫瘍融解ウイルス（OBP-301）や, coxsackie and adenovirus receptor（CAR）陰性の腫瘍細胞に感染するファイバー改変型ウイルス（OBP-405）を用い, 骨・軟部肉腫細胞に対する抗腫瘍効果を検討した.　 　14種類の骨・軟部肉腫細胞株に対してOBP-301の細胞障害活性を検討し, 12種類の細胞株でOBP-301に感受性を認めた.　また, OBP-301の細胞障害活性はCARの発現と相関していた.　さらに, テロメラーゼ活性の低い細胞に対しても, 5型アデノウイルスの複製に必須のE1Aによりテロメラーゼ活性の増強効果がおこり, 強い抗腫瘍活性を示すことを明らかにした.　次に, 骨肉腫脛骨同所性移植動物モデルを作成しOBP-301を投与したところ, OBP-301投与群では対象群と比べて有意に腫瘍増殖を抑制した.　最後に, OBP-301に感受性を認めなかったCAR陰性細胞株に対してOBP-405を用いて検討し, OBP-405が有効に作用することを確認した.　 　OBP-301やOBP-405を用いたウイルス療法は, 骨・軟部肉腫に対する新たな治療法となる可能性がある.　 en-copyright= kn-copyright= en-aut-name=SasakiTsuyoshi en-aut-sei=Sasaki en-aut-mei=Tsuyoshi kn-aut-name=佐々木剛 kn-aut-sei=佐々木 kn-aut-mei=剛 aut-affil-num=1 ORCID= en-aut-name=TazawaHiroshi en-aut-sei=Tazawa en-aut-mei=Hiroshi kn-aut-name=田澤大 kn-aut-sei=田澤 kn-aut-mei=大 aut-affil-num=2 ORCID= en-aut-name=HaseiJo en-aut-sei=Hasei en-aut-mei=Jo kn-aut-name=長谷井嬢 kn-aut-sei=長谷井 kn-aut-mei=嬢 aut-affil-num=3 ORCID= en-aut-name=KunisadaToshiyuki en-aut-sei=Kunisada en-aut-mei=Toshiyuki kn-aut-name=国定俊之 kn-aut-sei=国定 kn-aut-mei=俊之 aut-affil-num=4 ORCID= en-aut-name=YoshidaAki en-aut-sei=Yoshida en-aut-mei=Aki kn-aut-name=吉田晶 kn-aut-sei=吉田 kn-aut-mei=晶 aut-affil-num=5 ORCID= en-aut-name=HashimotoYuuri en-aut-sei=Hashimoto en-aut-mei=Yuuri kn-aut-name=橋本悠里 kn-aut-sei=橋本 kn-aut-mei=悠里 aut-affil-num=6 ORCID= en-aut-name=YanoShuya en-aut-sei=Yano en-aut-mei=Shuya kn-aut-name=矢野修也 kn-aut-sei=矢野 kn-aut-mei=修也 aut-affil-num=7 ORCID= en-aut-name=YoshidaRyosuke en-aut-sei=Yoshida en-aut-mei=Ryosuke kn-aut-name=吉田亮介 kn-aut-sei=吉田 kn-aut-mei=亮介 aut-affil-num=8 ORCID= en-aut-name=UnoFutoshi en-aut-sei=Uno en-aut-mei=Futoshi kn-aut-name=宇野太 kn-aut-sei=宇野 kn-aut-mei=太 aut-affil-num=9 ORCID= en-aut-name=KagawaShunsuke en-aut-sei=Kagawa en-aut-mei=Shunsuke kn-aut-name=香川俊輔 kn-aut-sei=香川 kn-aut-mei=俊輔 aut-affil-num=10 ORCID= en-aut-name=MorimotoYuki en-aut-sei=Morimoto en-aut-mei=Yuki kn-aut-name=森本裕樹 kn-aut-sei=森本 kn-aut-mei=裕樹 aut-affil-num=11 ORCID= en-aut-name=UrataYasuo en-aut-sei=Urata en-aut-mei=Yasuo kn-aut-name=浦田泰生 kn-aut-sei=浦田 kn-aut-mei=泰生 aut-affil-num=12 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name=藤原俊義 kn-aut-sei=藤原 kn-aut-mei=俊義 aut-affil-num=13 ORCID= en-aut-name=OzakiToshifumi en-aut-sei=Ozaki en-aut-mei=Toshifumi kn-aut-name=尾﨑敏文 kn-aut-sei=尾﨑 kn-aut-mei=敏文 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=7 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=8 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=9 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=10 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=11 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=12 en-affil= kn-affil=オンコリスバイオファーマ affil-num=13 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=14 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 en-keyword=アデノウイルス kn-keyword=アデノウイルス en-keyword=肉腫 kn-keyword=肉腫 en-keyword=ALT kn-keyword=ALT en-keyword=ヒトテロメラーゼ逆転写酵素 kn-keyword=ヒトテロメラーゼ逆転写酵素 END start-ver=1.4 cd-journal=joma no-vol=124 cd-vols= no-issue=1 article-no= start-page=83 end-page=85 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Complications of hand-foot-mouth disease kn-title=手足口病の合併症 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamashitaNobuko en-aut-sei=Yamashita en-aut-mei=Nobuko kn-aut-name=山下信子 kn-aut-sei=山下 kn-aut-mei=信子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　病原ウイルス学 END start-ver=1.4 cd-journal=joma no-vol=124 cd-vols= no-issue=1 article-no= start-page=75 end-page=77 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Japanese guidelines for the management of community-acquired pneumonia kn-title=市中肺炎の診療ガイドライン en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TanimotoYasushi en-aut-sei=Tanimoto en-aut-mei=Yasushi kn-aut-name=谷本安 kn-aut-sei=谷本 kn-aut-mei=安 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院　呼吸器・アレルギー内科 END start-ver=1.4 cd-journal=joma no-vol=124 cd-vols= no-issue=1 article-no= start-page=59 end-page=62 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Gastric aberrant pancreas with acute pancreatitis treated with surgery kn-title=膵炎を伴った胃異所性膵の1切除例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We experienced a case of gastric aberrant pancreas with acute pancreatitis. The patient was a 42-year-old man. He was referred to our hospital because of epigastric pain. A CT scan and endoscopic examination revealed a gastric submucosal tumor with inflammation. His serum amylase level was high at 222 IU/l. Endoscopic ultrasonography revealed a hypoechoic mass lesion, 3 cm in diameter, at the body of his stomach. Endoscopic ultrasoundscopy-guided fine needle aspiration was performed. Pathological examination showed pancreatic tissue. So, he underwent partial gastrectomy due to gastric aberrant pancreas with pancreatitis. There are very few cases of gastric aberrant pancreas with pancreatitis on record. en-copyright= kn-copyright= en-aut-name=ShinouraSusumu en-aut-sei=Shinoura en-aut-mei=Susumu kn-aut-name=篠浦先 kn-aut-sei=篠浦 kn-aut-mei=先 aut-affil-num=1 ORCID= en-aut-name=YagiTakahito en-aut-sei=Yagi en-aut-mei=Takahito kn-aut-name=八木孝仁 kn-aut-sei=八木 kn-aut-mei=孝仁 aut-affil-num=2 ORCID= en-aut-name=SadamoriHiroshi en-aut-sei=Sadamori en-aut-mei=Hiroshi kn-aut-name=貞森裕 kn-aut-sei=貞森 kn-aut-mei=裕 aut-affil-num=3 ORCID= en-aut-name=MatsudaHiroaki en-aut-sei=Matsuda en-aut-mei=Hiroaki kn-aut-name=松田浩明 kn-aut-sei=松田 kn-aut-mei=浩明 aut-affil-num=4 ORCID= en-aut-name=UmedaYuzo en-aut-sei=Umeda en-aut-mei=Yuzo kn-aut-name=楳田祐三 kn-aut-sei=楳田 kn-aut-mei=祐三 aut-affil-num=5 ORCID= en-aut-name=YoshidaRyuichi en-aut-sei=Yoshida en-aut-mei=Ryuichi kn-aut-name=吉田龍一 kn-aut-sei=吉田 kn-aut-mei=龍一 aut-affil-num=6 ORCID= en-aut-name=SatohDaisuke en-aut-sei=Satoh en-aut-mei=Daisuke kn-aut-name=佐藤太佑 kn-aut-sei=佐藤 kn-aut-mei=太佑 aut-affil-num=7 ORCID= en-aut-name=UtsumiMasashi en-aut-sei=Utsumi en-aut-mei=Masashi kn-aut-name=内海方嗣 kn-aut-sei=内海 kn-aut-mei=方嗣 aut-affil-num=8 ORCID= en-aut-name=YokomichiNaosuke en-aut-sei=Yokomichi en-aut-mei=Naosuke kn-aut-name=横道直佑 kn-aut-sei=横道 kn-aut-mei=直佑 aut-affil-num=9 ORCID= en-aut-name=KuiseTakashi en-aut-sei=Kuise en-aut-mei=Takashi kn-aut-name=杭瀬崇 kn-aut-sei=杭瀬 kn-aut-mei=崇 aut-affil-num=10 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name=藤原俊義 kn-aut-sei=藤原 kn-aut-mei=俊義 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=7 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=8 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=9 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=10 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=11 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 en-keyword=異所性膵 (ectopic pancreas) kn-keyword=異所性膵 (ectopic pancreas) en-keyword=迷入膵 (aberrant pancreas) kn-keyword=迷入膵 (aberrant pancreas) en-keyword=粘膜下腫瘍 (submucosal tumor) kn-keyword=粘膜下腫瘍 (submucosal tumor) en-keyword=急性膵炎 (acute pancreatitis) kn-keyword=急性膵炎 (acute pancreatitis) en-keyword=胃 (stomach) kn-keyword=胃 (stomach) END start-ver=1.4 cd-journal=joma no-vol=124 cd-vols= no-issue=1 article-no= start-page=5 end-page=8 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice kn-title=同種抗原による移植片対白血病効果減弱のメカニズム en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=AsakuraShoji en-aut-sei=Asakura en-aut-mei=Shoji kn-aut-name=朝倉昇司 kn-aut-sei=朝倉 kn-aut-mei=昇司 aut-affil-num=1 ORCID= en-aut-name=HashimotoDaigo en-aut-sei=Hashimoto en-aut-mei=Daigo kn-aut-name=橋本大吾 kn-aut-sei=橋本 kn-aut-mei=大吾 aut-affil-num=2 ORCID= en-aut-name=TakashimaShuichiro en-aut-sei=Takashima en-aut-mei=Shuichiro kn-aut-name=高嶋秀一郎 kn-aut-sei=高嶋 kn-aut-mei=秀一郎 aut-affil-num=3 ORCID= en-aut-name=SugiyamaHaruko en-aut-sei=Sugiyama en-aut-mei=Haruko kn-aut-name=杉山暖子 kn-aut-sei=杉山 kn-aut-mei=暖子 aut-affil-num=4 ORCID= en-aut-name=MaedaYoshinobu en-aut-sei=Maeda en-aut-mei=Yoshinobu kn-aut-name=前田嘉信 kn-aut-sei=前田 kn-aut-mei=嘉信 aut-affil-num=5 ORCID= en-aut-name=AkashiKoichi en-aut-sei=Akashi en-aut-mei=Koichi kn-aut-name=赤司浩一 kn-aut-sei=赤司 kn-aut-mei=浩一 aut-affil-num=6 ORCID= en-aut-name=TanimotoMitsune en-aut-sei=Tanimoto en-aut-mei=Mitsune kn-aut-name=谷本光音 kn-aut-sei=谷本 kn-aut-mei=光音 aut-affil-num=7 ORCID= en-aut-name=TeshimaTakanori en-aut-sei=Teshima en-aut-mei=Takanori kn-aut-name=豊嶋崇徳 kn-aut-sei=豊嶋 kn-aut-mei=崇徳 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=国立病院機構岡山医療センター　血液内科 affil-num=2 en-affil= kn-affil=岡山大学病院　血液・腫瘍内科 affil-num=3 en-affil= kn-affil=九州大学大学院　病態修復内科学 affil-num=4 en-affil= kn-affil=岡山大学病院　血液・腫瘍内科 affil-num=5 en-affil= kn-affil=岡山大学病院　血液・腫瘍内科 affil-num=6 en-affil= kn-affil=九州大学病院　遺伝子細胞療法部 affil-num=7 en-affil= kn-affil=岡山大学病院　血液・腫瘍内科 affil-num=8 en-affil= kn-affil=九州大学病院　遺伝子細胞療法部 en-keyword=同種造血幹細胞移植 kn-keyword=同種造血幹細胞移植 en-keyword=移植片対白血病効果 kn-keyword=移植片対白血病効果 en-keyword=programmed death-1 (PD-1) kn-keyword=programmed death-1 (PD-1) en-keyword=programmed death ligand-1 (PD-L1) kn-keyword=programmed death ligand-1 (PD-L1) END start-ver=1.4 cd-journal=joma no-vol=39 cd-vols= no-issue=8 article-no= start-page=1237 end-page=1267 dt-received= dt-revised= dt-accepted= dt-pub-year=1927 dt-pub=19270831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimentelle Studie über den Ikterus. (2. Mitteilung.) Ueber die Blutbefunde bei der Spirochätosis ictero-hämorrhagica und vergleichenden Resultate jedes Blutbefundes bei der Spirochätosis ictero-hämorrhagica, des Stauungsikterus, und desjenigen Ikterus, der durch die Injektion von Toluylendiamin herbeigefuhrt wurde kn-title=黄疸ニ關スル實驗的研究（第二囘報告） 黄疸出血性「スピロヘータ」病ノ血液所見ニ關スル實驗的研究 附 鬱滯性竝ニ「トルイレンヂアミン」黄疸ノ血液所見トノ比較 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Die Verfasser untersuchten die Blutbefunde bei der Spirochätosis ictero-hämorrhagica, dem Stauungsikterus und demjenigen Ikterus, der durch die Injektion von Toluylendiamin herbeigeführt wurde, und beobachteten die Beziehungen der Entstehungsweise des Ikterus bei der Spirochätosis ictero-hämorrhagica auf die Blutbefunde bei den drei obenerwähnten Arten von Ikterus. Als Versuchsmaterial benutzten wir die Hunde, Meerschweinchen, und Kaninchen. Aus den Resultaten haben wir die folgenden Schluesse gezogen: 1. Die Zahl der Erythrozyten vermindert rich ja sicher bei der Spirochätosis icterohämorrhagica mit dem Ausbruch derselben und besonders ist es am deutlichsten unmittelbar vor dem Ausscheinen des Ikterus, dagegen beim Stauungsikterus nimmt sie je mehr mit der Aufsteigung des Ikterus ab. Beim Toluyleudiaminikterus folgt sich eine sehr auffallendplötzliche verminderung in 24-48 Stunden nach der Injektion. 2. Der Faerbeiudex wird bei der Spirochätosis ictero-hämorrhagica von jedem Krankheitstadium kaum beeinflusst. Beim Stauungsikterus nimmt er parallel mit dem Hämoglobingehalt ab., und beim Toluylendiaminikterus vermindert sich er am deutlichsten in 24-48 Stunden nach der Injektion und dann mit dem Verschwinden des Ikterus in den früheren Zustand zurück. 3. Die Zahl der Leukozyten vermehrt sich bei der Spirochätosis ictero-hämorrhagica allmaehlich im Verlaufe der Krankheit, besonders findet man dabei bedeutende vermehrung der Polymorphkernigen ueutrophylen Leukozyten, beim Stauungsikterus wird sie wenig beeinflusst. Beim Toluylendiaminikterus vermehrt sie sich am deutlichsten in 24-48 Stunden nach der Injektion, besonders Polymorphkernige neutrophile Leuko-zyten. 4. Der Bilirubingehalt im Bluteserum vermehrt sich bei der Spirochätosis ikterohämorrhagica plötzlich direkt nach dem Ausbruch des Ikterus, und die direkte Diazoreaktion zeigt sich meist prompt, beim Stauungsikterus vermehrt er sich allmählich, beim Toluylendiaminikterus erreicht er seinen Höhepunkt in 24-48 Stunden nach der Injektion. 5. Die Resistenz der Erythrozyten gegen die hypotonische Kochsalzlösung ist bei der Spirochätosis ictero-hämorrhagica ganz unbestimmt, indem sie sich bei einem erhöht, beim anderen absteigt, beim Stauungsikterus vermehrt sie sich allmählich. Beim Toluylendiaminikterus nimmt sie dagegen in 24-48 Stunden nach der Injektion ab, und kehrt dan in den früheren Zustand wieder zurueck. 6. Die Menge des Serumeiweiss vermindert sich bei der Spirochätosis ictero-hämorr-hagika gewöhnlich nach und nach. Sowohl beim Stauungsikterus als auch beim Toluylendiaminikterus vermehrt sie sich allmählich parallel mit dem Bilirubingehalt im Blutserum. 7. Die Senkungsgeschwindigkeit der Erythrozyten verzögert sich bei der Spirochätosis ictero-hämorrhagica, und zwar im Ikterusstadium, als auch beim Stauungsikterus. Beim Toluylendiaminikterus beschleunigt sie sich dagegen. 8. Aus diesem Tatsachen kommt es heraus, dass der Blutbefund der Spirochätosis ictero-hämorrhagica mit dem des Stauungsikterus manche Aehnlichkeit hat. en-copyright= kn-copyright= en-aut-name=HasimotoMasaiti en-aut-sei=Hasimoto en-aut-mei=Masaiti kn-aut-name=橋本政一 kn-aut-sei=橋本 kn-aut-mei=政一 aut-affil-num=1 ORCID= en-aut-name=KuroseIwao en-aut-sei=Kurose en-aut-mei=Iwao kn-aut-name=黒瀨巖 kn-aut-sei=黒瀨 kn-aut-mei=巖 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學稻田内科教室 affil-num=2 en-affil= kn-affil=岡山醫科大學稻田内科教室 END start-ver=1.4 cd-journal=joma no-vol=39 cd-vols= no-issue=448 article-no= start-page=703 end-page=718 dt-received= dt-revised= dt-accepted= dt-pub-year=1927 dt-pub=19270531 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimentelle Studien über den Ikterus I. Mitteilung: Ueber die Gitterfasern der Leber beim Ikterus kn-title=黄疸ニ關スル實驗的研究 其一 肝臟ノ格子状繊維ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Es ist festgestellt, dass die Veränderungen des Parenchyms der Leber einige Beziehungen auf die Entstehungsweise gewisser Arten von Ikterus haben. Die Untersuchung der Fasern bei dem Ikterus ist deshalb sehr wichtig, weil dieselben zum Parenchym in engsten Beziehungen stehen. Aber über die Veränderungen der Gitterfasern bei dem Ikterus, der auf die verschiedene Weise experimentell bei den Tiere erzeugt war, leider gibt es keine genaue Angabe. Angeregt von dieser Sache, untersuchten die Verfasser die Beziehungen zwischen den Veränderungen der Gitterfasern der Leber und der Entstehungsweise des Ikterus, bei der Spirochötosis ictero-hämorrhagica, dem Stauungsikterus, der bei der Unterbindung des Ductus choledochus auftrat, und demjenigen Ikterus, der durch die Injektion von Toluylendiamin herbeigeführt wurde. Zur Färbungsmethode benutzten wir die Modifikation der Bilschowskyscheh Neurofiblillendarstellung, die Maresch angegeben hat. Als Versuchsmaterial benutzten wir die Hunde, Meerschweinchen und Kaninchen. Aus unseren Versuchsresultaten lautet folgende: 1. Die Gitterfasern der Leber werden bei dem Stauungsikterus gut erhaltet, sogar kommen sie (Radiärfasern sowie umspinnende Fasern) grösstenteils zu Hypertrophie und Hyperplasie. 2. Die Gitterfasern der Leber werden bei dem Toluyllendiaminikterus gut erhalten. 3. Die Gitterfasern, besonders umspinnende Fasern verminderten sich bei der Spirochätosis ictero-hämorrhagica nach dem Ausbruch des Ikterus. 4. Beim Stauungs- und Toluylendiamin-ikterus können wir keine bestimmte Beziehungen zwischen den Veränderungen der Gitterfasern der Leber und der Entstehungsweise des Ikterus herausfinden. Die Gitterfasern werden bei der Spirochätosis ictero hämorrhagica locker. Das geschieht auch häufig bei den Infektionskrankheiten Also Kann die Verminderung der Gitterfasern zwar eine Ursache zur Entstehung des Ikterus sein, aber es ist keine einzige Ursache des Ikterus. en-copyright= kn-copyright= en-aut-name=KuroseIwao en-aut-sei=Kurose en-aut-mei=Iwao kn-aut-name=黒瀬巖 kn-aut-sei=黒瀬 kn-aut-mei=巖 aut-affil-num=1 ORCID= en-aut-name=HasimotoMasaiti en-aut-sei=Hasimoto en-aut-mei=Masaiti kn-aut-name=橋本政一 kn-aut-sei=橋本 kn-aut-mei=政一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學稻田内科教室 affil-num=2 en-affil= kn-affil=岡山醫科大學稻田内科教室 END start-ver=1.4 cd-journal=joma no-vol=123 cd-vols= no-issue=2 article-no= start-page=129 end-page=132 dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Laparoscopic surgery for mesenteric Castleman's disease kn-title=腹腔鏡下に摘出しえた上行結腸間膜発生のCastleman病の１例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We report herein a case of mesenteric Castleman's disease which was confirmed on pathology. A 60-year-old man was admitted to our hospital complaining of abdominal pain. On the physical examination, there was no palpable mass. Computed tomography findings and magnetic resonance imaging revealed a well circumscribed, lobulated round mass on the right side of the superior mesenteric vein. Laparoscopic surgery for the mesenteric tumor was carried out to obtain a definite diagnosis and treatment. In the operative field, the mass was located on the ascending colic mesentery and measured about 3 cm in size. It was solid and surrounded by a thin fibrous capsule. The histological diagnosis of the mesenteric tumor was hyaline vascular type Castleman's disease. The postoperative course of the patient was uneventful, and he was discharged on the 10th postoperative day. en-copyright= kn-copyright= en-aut-name=NishieManabu en-aut-sei=Nishie en-aut-mei=Manabu kn-aut-name=西江学 kn-aut-sei=西江 kn-aut-mei=学 aut-affil-num=1 ORCID= en-aut-name=OtsukaShinya en-aut-sei=Otsuka en-aut-mei=Shinya kn-aut-name=大塚真哉 kn-aut-sei=大塚 kn-aut-mei=真哉 aut-affil-num=2 ORCID= en-aut-name=TomodaJun en-aut-sei=Tomoda en-aut-mei=Jun kn-aut-name=友田純 kn-aut-sei=友田 kn-aut-mei=純 aut-affil-num=3 ORCID= en-aut-name=FujiwaraKeishi en-aut-sei=Fujiwara en-aut-mei=Keishi kn-aut-name=藤原敬士 kn-aut-sei=藤原 kn-aut-mei=敬士 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=2 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=3 en-affil= kn-affil=国立病院機構福山医療センター　内科 affil-num=4 en-affil= kn-affil=光生病院　内科 en-keyword=結腸間膜 (mesocolon) kn-keyword=結腸間膜 (mesocolon) en-keyword=Castleman病 (Castleman's disease) kn-keyword=Castleman病 (Castleman's disease) en-keyword=腹腔鏡手術 (laparoscopic surgery) kn-keyword=腹腔鏡手術 (laparoscopic surgery) END start-ver=1.4 cd-journal=joma no-vol=123 cd-vols= no-issue=2 article-no= start-page=103 end-page=109 dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Radiosensitization by telomerase-dependent oncolytic adenovirus kn-title=テロメラーゼ依存的腫瘍融解アデノウイルス製剤による 放射線感受性増強作用 en-subtitle= kn-subtitle= en-abstract= kn-abstract=DNA修復機能阻害は放射線感受性を増強させるため，DNA修復に関与する因子の阻害剤は放射線増感剤となり得る．我々の開発したテロメラーゼ依存的腫瘍融解アデノウイルス製剤OBP-301（テロメライシン）は，アデノウイルスE1B55kDaタンパクを介して細胞のDNA修復に重要な役割を果たすMRN複合体（Mre11，Rad50，NBS1）を分解する機能を有する．このMRN複合体の分解によりATM（ataxia-telangiectasia mutated）の活性化が抑制され結果的にDNA修復機構が阻害される．我々はOBP-301と放射線との併用が強力な相乗効果を生み出すことをマウスの皮下腫瘍モデルおよび食道癌同所性モデルにおいて証明した．これらの結果はOBP-301が将来有望な放射線増感剤となり得ることだけでなく，E1B55kDaタンパクを産生する腫瘍融解アデノウイルス製剤と放射線との併用が悪性腫瘍に対する有力な治療戦略となり得ることを示す． en-copyright= kn-copyright= en-aut-name=KurodaShinji en-aut-sei=Kuroda en-aut-mei=Shinji kn-aut-name=黒田新士 kn-aut-sei=黒田 kn-aut-mei=新士 aut-affil-num=1 ORCID= en-aut-name=FujiwaraToshiya en-aut-sei=Fujiwara en-aut-mei=Toshiya kn-aut-name=藤原俊哉 kn-aut-sei=藤原 kn-aut-mei=俊哉 aut-affil-num=2 ORCID= en-aut-name=ShirakawaYasuhiro en-aut-sei=Shirakawa en-aut-mei=Yasuhiro kn-aut-name=白川靖博 kn-aut-sei=白川 kn-aut-mei=靖博 aut-affil-num=3 ORCID= en-aut-name=YamasakiYasumoto en-aut-sei=Yamasaki en-aut-mei=Yasumoto kn-aut-name=山崎泰源 kn-aut-sei=山崎 kn-aut-mei=泰源 aut-affil-num=4 ORCID= en-aut-name=YanoSyuya en-aut-sei=Yano en-aut-mei=Syuya kn-aut-name=矢野修也 kn-aut-sei=矢野 kn-aut-mei=修也 aut-affil-num=5 ORCID= en-aut-name=UnoFutoshi en-aut-sei=Uno en-aut-mei=Futoshi kn-aut-name=宇野太 kn-aut-sei=宇野 kn-aut-mei=太 aut-affil-num=6 ORCID= en-aut-name=TazawaHiroshi en-aut-sei=Tazawa en-aut-mei=Hiroshi kn-aut-name=田澤大 kn-aut-sei=田澤 kn-aut-mei=大 aut-affil-num=7 ORCID= en-aut-name=HashimotoYuuri en-aut-sei=Hashimoto en-aut-mei=Yuuri kn-aut-name=橋本悠里 kn-aut-sei=橋本 kn-aut-mei=悠里 aut-affil-num=8 ORCID= en-aut-name=WatanabeYuichi en-aut-sei=Watanabe en-aut-mei=Yuichi kn-aut-name=渡辺雄一 kn-aut-sei=渡辺 kn-aut-mei=雄一 aut-affil-num=9 ORCID= en-aut-name=NomaKazuhiro en-aut-sei=Noma en-aut-mei=Kazuhiro kn-aut-name=野間和広 kn-aut-sei=野間 kn-aut-mei=和広 aut-affil-num=10 ORCID= en-aut-name=UrataYasuo en-aut-sei=Urata en-aut-mei=Yasuo kn-aut-name=浦田泰生 kn-aut-sei=浦田 kn-aut-mei=泰生 aut-affil-num=11 ORCID= en-aut-name=KagawaShunsuke en-aut-sei=Kagawa en-aut-mei=Shunsuke kn-aut-name=香川俊輔 kn-aut-sei=香川 kn-aut-mei=俊輔 aut-affil-num=12 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name=藤原俊義 kn-aut-sei=藤原 kn-aut-mei=俊義 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=7 en-affil= kn-affil=岡山大学病院　遺伝子・細胞治療センター affil-num=8 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=9 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=10 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=11 en-affil= kn-affil=オンコリスバイオファーマ株式会社 affil-num=12 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=13 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 en-keyword=アデノウイルス kn-keyword=アデノウイルス en-keyword=E1B55kDa kn-keyword=E1B55kDa en-keyword=MRN複合体 kn-keyword=MRN複合体 en-keyword=DNA修復 kn-keyword=DNA修復 en-keyword=放射線感受性 kn-keyword=放射線感受性 END start-ver=1.4 cd-journal=joma no-vol=43 cd-vols= no-issue=10 article-no= start-page=2557 end-page=2604 dt-received= dt-revised= dt-accepted= dt-pub-year=1931 dt-pub=19311031 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über den Erreger des progressiven Lymphogranuloms kn-title=進行性淋巴肉芽腫ノ病原體ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Mir begegnete in unserer Klinik ein 39 jähriger Mann, dessen Krankheit durch 5 Monate lange klinische Beobachtung und auf Grund der Sektionsbefunde als progressives Lymphogranulom diagnostziert wurde. Man bemerkte an der exetirpierten oberflächlichen vergröserten Lymphdrüse ein Gram positiver Kokken und konnte durch genaue bacteriologische Untersuchung mit Sicherheit nachweisen, dass er durch, diese Kokken infiziert worden war. Weiter habe ich Kaninchen, Meerschweinchen und Affen mit diesen Kokken geimpft, und konnte feststellen, dass bei diesen Tieren die Lymphdrüse wie bei progressievem Lymphogranulom verändert wurde, und dass diese Kokken in die granulierten Gewebe eingedrungen waren. Auf Grund dieser Befunde kann ich also annehmen, dass diese Kokken der Erreger des progressiven Lymphogranuloms sind, es zum wenigsten bei diesem Kranken waren. en-copyright= kn-copyright= en-aut-name=HashimotoTohru en-aut-sei=Hashimoto en-aut-mei=Tohru kn-aut-name=橋本亨 kn-aut-sei=橋本 kn-aut-mei=亨 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學泉外科教室 END start-ver=1.4 cd-journal=joma no-vol=43 cd-vols= no-issue=3 article-no= start-page=612 end-page=620 dt-received= dt-revised= dt-accepted= dt-pub-year=1931 dt-pub=19310331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über den Einfluss der periarteriellen Sympathektomie auf die Heilung des Einfachgeschwürs kn-title=單純性潰瘍ニ及ボス動脉外膜剥離術ノ影響ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Ich habe neulich in unserer Klinik bei meinen 7 Kranken mit Einfachgeschwür (4 Einfachgeschwüre am Unterschenkel infolge chronischer recidivierender Osteomyelitis der Tibiae, ein narbiges, ein traumatisches Unterschenkelgeschwür, und Brandgeschwür an der Hand) die periarterielle Sympathektomie versucht und die folgenden Resultate erhalten. 1. Die periphere Hauttemperatur des operierten Gliedes stieg immer einige Tage nach der Operation an. 2. Ca. eine Woche nach der Operation waren alle Geschwürböden sehr rein und bedekten sich sogleich mit frischem lebhaftem Granurationsgewebe. 3. Durch diese Operation heilten alle Geschwüre immer sehr schnell. 4. Die Operationswunde der periarteriellen Sympathektomie war im ganzen nach einer Woche primär geheilt, Eiterung oder Klaffung ist bei ihr niemals aufgetreten. 5. Diese Operation brachte keine Gefahr für die Gefässe und das Leben mit sich. 6. Durch die periarterielle Sympathektomie wird nämlich Blutmenge, die im Versorgungsgebiet der operierten Arteria zirkuliert, vermehrt und die Ernährung jenes Gebietes sehr gefördert, wodurch die Heilung der Geschwür sehr beschleunigt wird. Daher muss man bei der Behandlung des hartnäckigen Einfachgeschwürs auf alle Fälle diese Operation versuchen. en-copyright= kn-copyright= en-aut-name=HashimotoToru en-aut-sei=Hashimoto en-aut-mei=Toru kn-aut-name=橋本亨 kn-aut-sei=橋本 kn-aut-mei=亨 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學泉外科教室 END start-ver=1.4 cd-journal=joma no-vol=44 cd-vols= no-issue=2 article-no= start-page=245 end-page=288 dt-received= dt-revised= dt-accepted= dt-pub-year=1932 dt-pub=19320229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über die unspezifische pharmakologische Wirkung der parenteral eingespritten Lösung kn-title=非經口的液體注入ノ非特異藥物學的作用ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=1) Durch intravenöse Injection von Lösungen mannigfaltiger Substanzen mit verschiedenen Konzentration werden die Ausflüsse der Lebergalle plötzlich vermindert und die direkte und indirekte Bilirubineinheit der Galle vermehrt. Die Vermehrung der indirekten Bilirubineinheit ist besonders hochgradig und der Bilirubinindex (I. B. E./D. B. E.) vergrössert. Zuweilen vermindert die gesamte Menge des direkten Bilirubins in der Galle wegen der Verminderung der Gallenmenge selbst vorläufig, wird aber gewöhnlich sofort wiederhergestellt und sogar dann einwenig vermehrt. Dagegen ist die Vermehrung der gesamten Menge des indirekten Bilirubins erheblicher als die des direkten Bilirubin. Im Serum vermehrt immer das indirekte Bilirubin durch diese parenterale Einspritzung der Lösung. 2) Die obengenannten Veränderungen sind unabhängig von Art sowie Konzentration der gelösten stoffe, sondern stehen im Verhältnisse zur gesamten Menge der injizierten Lösung. 3) Die obengenannte Veränderungen treten nicht auf bei subcutaner oder intraperitonealer Injection der Lösung. 4) Die obengenannte Bilirubinvermehrung in der Galle und im Serum hat ihren Ursprung hauptsächlich in der Zunahme der Bilirubinbildung, die durch die Steigerung der Funktion der allgemeinen reticuloendothelialen Zellen verursacht wurde. 5) Die obengenannten Veränderungen zeigen sich nicht nur bei Tieren, sondern auch beim Menschen, darum glaube ich dass diese Tatsache klinische von bedeutungsvoll ist. 6) Es scheint, dass die Milz ausser der Substanz, die die allgemeinen reticuloendotherialen Zellen reizt, auch noch eine andere Substanz sezerniert, die die Gallenausschei-dungsfunktion der Leber beeinflusst. Ich vermute, dass diese beiden Substanzen nicht identisch seien. en-copyright= kn-copyright= en-aut-name=HashimotoTohoru en-aut-sei=Hashimoto en-aut-mei=Tohoru kn-aut-name=橋本亨 kn-aut-sei=橋本 kn-aut-mei=亨 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學泉外科教室 END start-ver=1.4 cd-journal=joma no-vol=46 cd-vols= no-issue=12 article-no= start-page=3137 end-page=3145 dt-received= dt-revised= dt-accepted= dt-pub-year=1934 dt-pub=19341231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über die statistische Beobachtung der Rippenkaries kn-title=肋骨「カリエス」ノ統計的觀察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Bei 86 Kranken, die während der letzten 8 Jahre wegen kalten Abszesses an der Thoraxwand in unsere chirurgische Klinik von Prof. Dr. Tsuda aufgenommen wurden, nahm ich statistische Beobachtungen vor. Da bemerkte ich in nur wenigen Fällen die primäre Rippenkarjes, in den meisten Fällen aber die sekundäre, d. h. die Arrosionskaries. 25 Fälle, d. h. 29% der Kranken sind solche, die an Lungentuberkulose leiden oder einst gelitten haben. Ganz dasselbe gilt auch bei der Pleuritis. Unter den familiären Erkrankungen steht die Lungentuberkulose an der Spitze, i. e. 7 Fälle (8,1%), und in der Familie leiden meistens die Geschwister an ihr. Diese Krankheit tritt im Alter von 21-30 Jahren am häufigsten auf, i. e. 55,8% der Gesamtzahl. Kinder unter 10 Jahren und Alte über 51 Jahren leiden an ihr sehr selten. Männer sind starker vertreten als Frauen, das Verhältnis ist 55:31. Der Lieblingssitz des Leidens ist die 3. und 4. Rippe. Die Erkrankungen an dieser Stelle betragen 18,5% von der Gesamtzahl; den Sitz an der vorderen Brustwand, und zwar an der rechten Seite, findet man am häufigsten. Das Heilungsresultat bei dieser Krankheit in unserer chirurgischen Klinik von Prof. Dr. Tsuda ist 97,7%. en-copyright= kn-copyright= en-aut-name=HashimatoKen en-aut-sei=Hashimato en-aut-mei=Ken kn-aut-name=橋本健 kn-aut-sei=橋本 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=46 cd-vols= no-issue=6 article-no= start-page=1175 end-page=1188 dt-received= dt-revised= dt-accepted= dt-pub-year=1934 dt-pub=19340630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über die primare Kieferaktinomykose kn-title=原發性顎骨放線状菌病ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Neuerdings behandelte ich 4 Fälle von primärer Kieferaktinomykose. 1. Fall. Eine 20 jährige Bauerntochter: Auf Grund eines erschwerten Zahnausbruchs am linken Unterkiefer begann die Krankheit mit heftigem Schmerz, Anschwellung an Gingiva und Wange und mit hochgradiger Kieferklemme. Während der Behandlung als Unterkieferperiostitis wurde aktinomykotische Druse im Eiter nachgewiesen. Durch Auskratzung des Krankheitsherdes, Eingeben einer grossen Dose Jodkali und durch Röntgentherapie wurde die Krankheit ausgeheilt. 2. Fall. Ein 14 jähriger Schuljunge: Zuerst hatte der Kranke Schmerz und Anschwellung an der Gingiva um den linksseitigen grossen Mahlzahn herum, dann entwickelte sich eiue harte Anschwellung rings um den Unterkieferrand derselben Seite.Von einem Arzt wurde an der erkraktep Stelle eine Inzision gemacht, woraufhin sich eine Eiterung bildete. Im Eiter war aktinomykotische Druse zu finden. Diese Krankheit wurde ebenfalls durch die oben genannte Bahandlung ausgeheilt. 3. Fall. Eine 23 jährige Bauernfrau: Mit Anschwellung und heftigem Schmerz an der rechten Wange nahm die Krankheit ihren Anfang. Nach Rontgenaufnahme als Oberkieferperiostitis diagnostiert, wurde der frau eine Inzision empfohlen. Aber sie willigte nicht ein. Nach der Inzision, die von einem Arzt gemacht wurde, bildeten sich viele Fisteln an der Wange. Endlich wurde die Kranke in unsere Klinik aufgenommen. Bei Untersuchungen wumde aktinomykotische Druse (Israelsche Form) im Eiter nachgewiesen. F ür lange Zeit wurde die obige Behandlung fortgesetzt, bis die Frau als ganz geheilt entlassen werden konnte. 4. Fall. Eine 72 j ährige Bauernfrau: Zuerst äusserte sich die Krankheit in Schmerz und Anschwellung des rechtsseitigen Unterkiefers, dann bekam die Frau Kieferklemme und Fisteln in der Gegend des rechten Unterkiefers. Ich konnte aktinomykoti- sche Druse (Bostromsche Form) im Eiter finden. Nach der oben erwähnten Behandlung ist sie bedeutend gebessert. Es gibt zwei Arten von Kieferaktinomykose: primäre und sekundäre. Die primäre kommt selten vor, sie hat periphere Form (od. periostale Form) und zentrale Form. Der 1. und 3. Fall kann als periphere Form, der 2. und 4. Fall dagegen als zentrale Form gelten. Als Haupteintrittspforte des Pilzes wird die Zahnkaries betrachtet, er tritt jedoch auoh oft an Gingiva und Mundschleimhaut ein, selten dagegen beginnt die Infektion nach dem Trauma des Kiefers und der Mundschleimhaut. Zur Diagnose ist Nachweis der Druse erforderlich. Als Differentialdiagnose sind maligne Geschwulst des Kiefers, Adamantinom, Zyste und Periostitis usw. zu nennen. Prognose: Wenn die Krankheit in ihrem Beginn richtig behandelt wird, ist die Heilung sicher. Behandlung: Auskratzung von Fisteln und Abszessen, Eingeben eiuer grossen Dose Jodkali und Röntgentherapie. en-copyright= kn-copyright= en-aut-name=HashimotoK. en-aut-sei=Hashimoto en-aut-mei=K. kn-aut-name=橋本健 kn-aut-sei=橋本 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=46 cd-vols= no-issue=2 article-no= start-page=294 end-page=303 dt-received= dt-revised= dt-accepted= dt-pub-year=1934 dt-pub=19340228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über die Calvé-Legg-Perthessche Krankheit kn-title=Calvé-Legg-Perthes氏病ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Neuerdings behandelte ich 3 Falle der Calvé-Legg-Perthesschen Krankheit. Der 1. Fall. Ein 9 jähriger Knabe, der seit etwa einem halben Jahr linkseitig hinkte, war von einem Landarzt auf Hüftgelenktuberkulose diagnostiziert worden und zeigte 1cm Verkürzung am linken Bein, leichte Muskelatrophie am Oberschenkel und Einschränkung der Abduktion. Der Rontgenbefund galt als 1. Stadium nach Amstad. Der 2. Fall. Ein 11 jähriger Knabe bekam seit etwa einem Jahre linkseitigen Hinkengang, der sich langsam aber immerhin merklich verschlimmerte. Bei ihm waren zu sehen Muskelatrophie am Oberschenkel und Abduktionsstörung. Der Röntgenbefund galt als 1. Stadium. Der 3. Fall. Bei einem 8 jährigen Knabe, der seit etwa 1 Jahr linkseitig hinkte, waren Muskelatrophie am Oberschenkel und Abduktions-und Abduktionsstorung zu finden. Die Krankheit trifft gewohnlich gesunde Kinder, meist Knaben von 4-13 Jahren, und beginnt ganz allmählich, manchmal im Anschluss an unbedeutendes Trauma, mit wenig Schmerzen, Hinken und Ermüdbarkeit. Später treten Abduktions-und Rotauionsstörung des Hüftgelenks und Verkürzung des Beines auf. Das Trendelenburgsche Phänomen ist positiv. Das Röntgenbild zeigt eine eigentümliche Deformität des Femurkopfes und-halses. Die Prognose ist meistens günstig. Die hochgradige Bewegungsstorung bleibt nicht sehr oft. Als Behandlung lässt sich nur konservativer, entlastender Abduktionsgipsverband und Gehapparat empfehlen. en-copyright= kn-copyright= en-aut-name=HashimotoKen en-aut-sei=Hashimoto en-aut-mei=Ken kn-aut-name=橋本健 kn-aut-sei=橋本 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=48 cd-vols= no-issue=4 article-no= start-page=683 end-page=694 dt-received= dt-revised= dt-accepted= dt-pub-year=1936 dt-pub=19360430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über die Veränderungen des Pankreas bei den experimentellen akuten Oberbauchperitonitiden (II. Mitteilung.) Über die histologischen Veränderungen des Pankreas kn-title=實驗的上腹部急性腹膜炎ニ於ケル膵臟ノ變化 後篇 膵臟ノ組織學的所見ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=In der ersten Mitteilung habe ich die Beteiligung des Pankreas bei den akuten Oberbauchperitonitiden durch die Messung der Pankreasfermente im Blute und im Harn festgestellt. Die histologischen Veränderungen des Pankreas bei diesen können folgendermassen zusammengefasst werden: 1) Die wichtigsten Befunde im Pankreas bei den akuten Oberbauchperitonitiden sind Blutung, Blutstauung, Atrophie der Drüsenzellen und die verschiedenen Degenerationen der Drüsenzellen, d. h., trübe schwellung, Vakuolendegeneration, Karyorrhexis, Pyknose und Auslösung des Epithelkernes etc. Eine Entzündung wird selten bemerkt. Derartige Befunde sind bei den Peritonitiden durch W. F. sche Bazillen und Streptokokkon am hochgradigsten und ergeben ein der akuten Pankreasnekrose sehr ähnliches Bild. 2) Nach der Malloryschen Bindegewebefärbung sind die Zymogenkörnchen in ihrer Grösse feiner, ihre Zahl niuimt ab und sie verschwinden sogar. Eine Wucherung des Bindegewebes tritt sehr selten auf. 3) Nach der Sudan III Färbung wird eine fettige Degeneration nicht bemerkt. 4) Die Golgischen Apparate des Pankreas nehmen zu und sind als grössere Körner und Knäuel sichtbar. 5) Die Mitochondrien des Parkreas nehmen ab und erscheinen als feinere Körner. 6) Ab- und Zunahme der Golgischen Apparate und der Mitochondrien stehen im umgekehrten Verhältuis. Nach den histologischen Befunden ist die Veränderung des Pankreas bei den Peritonitiden durch W. F. sche Bazillen am hochgradigsten, die bei den Peritonitiden durch Streptokokken steht jener am nächsten. Die Veränderung bei den Peritonitiden durch Kolibazillen und Streptokokken ist mässig und die bei der Perforationsperitonitis des Magens ist am geringsten. Die Resultate stimmen mit denen bei der Funktionsprüfung des Pankreas überein. en-copyright= kn-copyright= en-aut-name=HashimotoKen en-aut-sei=Hashimoto en-aut-mei=Ken kn-aut-name=橋本健 kn-aut-sei=橋本 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=48 cd-vols= no-issue=2 article-no= start-page=284 end-page=313 dt-received= dt-revised= dt-accepted= dt-pub-year=1936 dt-pub=19360229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimentellen Studien über die Todesursache bei der akuten Pankreasnekrose kn-title=急性膵臟壞死ノ死因ニ關スル實驗的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Der Tod bei akuter Pankreasnekrose soll nach den experimentellen Versuchen von Guleke und Bergmann auf eine Trypsinvergiftung zurückzuführen sein. Neuerdings habe ich verschiedene Versuche ausgeführt, um die Todesursache bei akuter Pankreasnekrose festzustellen. Ich führte eine gewisse Menge der einzelnen Fermente der Pankreasdrüse, d. h., Trypsin (Grübler), Lipase (Digestive Ferment Co. u. s. a.), Diastase (Kashiwagi), oder Zusammen 2 oder 3 Arten der Fermente oder Protamylase, welche in physiologischer Kochsalzlösung gelöst sind, in die Bauchhöhle des Kaninchens oder der Hundes ein, Auf diese Weise konnte ich bei den Tieren experimentell dasselbe Krankheitsbild der Peritonitis erzeugen, welches ich in unserer Klinik bei der akuten Pankreasnekrose beobachtete. Nach den pathologischen Befunden in der Bauchhöhle und der Thoraxhöhle, insbesondere nach den histologischen Untersuchungen der lebenswichtigen Organe, d. h., der Lunge, Leber, Milz, Niere und des Pankreas, und nach den hämatologischen Untersuchungen konnte ich meine Resultate folgeudermassen zusammenfassen: 1.) Die Trypsinvergiftungstheorie kaun nicht angenommen werden. 2.) Die einzelnen äusseren Sekretionsfermnente zeigen gemeinschaftliche Vergiftungserscheinungen. Die Stärke der Giftigkeit der einzelnen Fermente ist verschieden. 3.) Unter den einzelnen äusseren Sekretionsfermenten ist die Vergiftung der Diastase am schwächsten, die der Lipase am stärksten. 4.) Wenn die 3 Fermente zusammen angewandt werden, ist diese Wirkung stärker als die der Lipase. 5.) Im ganzen ist die Giftigkeit der Protamylase am stärksten, die aus dem Pankreas des Schweines unter fast natürlichen Verhältnissen extrahiert wird und 3 Fermente mit Hormon enthält. Nach den obigen Ergebnissen soll als Todesursache bei der akuten Pankreasnekrose die gemeinsame Wirkung der 3 Pankreasfermente angenommen werden, die bis jetzt noch von niemand berücksichtigt wurde. Die 3 Fermente können zusammen eine Vergiftungserscheinung erzeugen, die als akute Pankreasnekrose manifest wird, die lebenswichtigen Organe verdaut, nekrotisiert, manchmal in ihnen eine starke Blutung hervorruft und schliesslich zum Tode führt. en-copyright= kn-copyright= en-aut-name=HashimotoKen en-aut-sei=Hashimoto en-aut-mei=Ken kn-aut-name=橋本健 kn-aut-sei=橋本 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=48 cd-vols= no-issue=2 article-no= start-page=257 end-page=283 dt-received= dt-revised= dt-accepted= dt-pub-year=1936 dt-pub=19360229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über die Veränderungen des Pankreas bei den experimentellen akuten Oberbauchperitonitiden (I. Mitteilung.) Der Diastasegehalt des Serums und des Urins, und der Lipasegehalt des Serums bei den experimentellen akuten Oberbauchperitonitiden kn-title=實驗的上腹部急性腹膜炎ニ於ケル膵臟ノ變化 前篇 血清竝ニ尿中Diastase, Lipaseノ消長ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Um die Beteiligung des Pankreas an den akuten diffusen Peritonitiden festzustellen, studierte ich am Hunde experimentell die akuten Oberbauchperitonitiden, die in verschiedener Weise, d. h., durch Perforation des Magens und durch Berieselung der Bouillonkultur von verschicdenen Bakterien (Staphylokokken, Kolibazillen, Streptokokken und Welch-Fränkelsche Bazillen) erzeugt wurden. Ich beobachtete zuerst die Ab- und Zunahme der Diastase im Serum und Urin, und die der Lipase im Serum. Den Diastasegehalt des Serums und des Urine habe ich nach der Wohlgemuthschen Methode und den Lipasegehalt des Serums nach der Rona-Michaelisschen Methode stalagnometrisch gemessen. Meine Resultate konnte ich folgendermassen zusammenfassen. I. Unter den obigen Peritonitiden zeigt die Entzündung durch W. F. sche Bazillen den höchsten Grad. Die Blutung und Blutstauung im Eingeweide ist babei sehr deutlich, das Paukreas ist angeschwollen und blutet multipel. Die Peritonitis durch Streptokokken zeigt den zweithöchsten Grad, die Peritonitis durch Kolibazillen ist am leichtesten. Bei der Staphylokokkenperitonitis und der Perforationsperitonitis des Magens werden die Verwachsung mit dem einzelnen Eingeweide und der Eiterbelag nachgewiesen. Und bei derjenigen der Kolibazillen, der Staphylokokken, und dei der Perforation des Magens ergaben sich makroskopisch keine Veränderungen im Pankreas. II. Der Diastasegehalt des normalen Hundeserums ist d_ 38°/30'_=8-32, und der des normalen Hundeharnes d_ 38°/30'_=8-64. Dieser wert ist auch beim Menschen fast der gleiche. III. Der Lipasegehalt des normalen Hundeserums ist individuell verschieden, aber im grossen und ganzen liegt die Tropfenzahldifferenz unter gtt. 8. Beim Menschen beträgt die Trofenzahldifferenz gtt. 6. IV. Der Diastasegehalt bei den verschiedenen experimentellen akuten Oberbauchperitonitiden stellt sich folgendermassen: 1.) Der Diastasegehalt des Serums bei der Perforationsperitonitis des Magenkörpers und des Pylorusteiles ist d_ 38°/30'_=32-64, der des Urins d_ 38°/30'_=68-128. Die Perforationsstelle und der Diastasewert sind unabhängig voneinander. 2.) Der Diastasegehalt des Serums bei der Staphyiokokkenperitonitis ist d_ 38°/30'_=128-256, der des Urins d_ 38°/30'_=128-256. 3.) Der Diastasegehalt des Serums bei der Kolibazillenperitonitis ist d_ 38°/30'_=64-256, der des Urins d_ 38°/30'_=256-512. 4.) Der Diastasegehalt des Serums bei der Streptokokkenperitonitis ist d_ 38°/30'_=128-256, der des Urins d_ 38°/30'_=256-1024. 5.) Der Diastasegehalt des Serums bei der W. F. schen Bazillenperitonitis ist d_ 38°/30'_=256-2048, der des Urins d_ 38°/30'_=256-4096. Und im ganzen steht die Steigerung dieses Diastasegehaltes an der Spitze. V. Der atoxylfeste Lipasegehalt im Serum bei den verschiedenen experimentellen akuten Oberbauchperitonitiden stellen sich folgendermassen: 1.) Die Tropfenzahldifferenz bei der Perforationsperitonitis des Magenkörpers und des Pylorusteiles ist gtt. 5-8. 2.) Bei der Staphylokokkenperitonitis ist sie gtt. 7-13. 3.) Bei der Kolibazillenperitonitis ist sie gtt. 10-15. 4.) Bei der Streptokokkenperitonitis ist sie gtt. 12-15. 5.) Bei der W. F. schen Bazillenperitonitis ist sie gtt. 13-17, und im ganzen steht dieser Fall an der Spitze. Nach den oben augeführten Resultaten wird das Pankreas bei den akuten Oberbauchperitonitiden meistens beeinflusst. Aber die genaueren Veränderungen des Pankreas müssen wir noch histologisch untersuchen. Auf Grund der Funktionsprüfungen des Pankreas wird das Pankreas bei der W. F. schen Bazillenperitonitis am stärksten beeinflusst, dem nächst bei der Streptokokkenperitonitis. Der Einfluss bei der Kolibazillenperitonitis oder der Perforationsperitonitis des Magens ist am geringsten. Nach den makroskopischen Befunden des Pankreas und nach der Messung der Lipase und der Diastase im Serum und Urin kann man sagen, dass die Veränderungen des Pankreas bei der W. F. schen Bazillenperitonitis und bei einigen Fallen der Streptokokkenperitonitis ein Bild ergeben, das dem einer akuten Pankreasnekrose sehr ahulich ist. en-copyright= kn-copyright= en-aut-name=HashimotoKen en-aut-sei=Hashimoto en-aut-mei=Ken kn-aut-name=橋本健 kn-aut-sei=橋本 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=51 cd-vols= no-issue=11 article-no= start-page=2342 end-page=2371 dt-received= dt-revised= dt-accepted= dt-pub-year=1939 dt-pub=19391130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the rachitis of newborns. (Part 3) Experimental studies of the effect of malnutrition during pregnancy upon mother and newborn, with special reference to the diet lacking in Vitamine D and having Ca. P. disharmony. kn-title=新産兒佝僂病問題ニ就テノ檢討（第3報）榮養失調ノ母體及ビ産兒ニ及ボス影響ニ關スル實驗的研究特ニ「ビタミンD」缺乏及ビCa, P平衡失調食餌ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=In view of contributing to the discussion about the rickets of newborn, whether an antenatal factor can play an etiological role or not, a following experiment was carried out. White rats were used as experimental animals, and a diet provoking rickets after Steenbock No. 2965 was administered, the component of which being partially changed. Then the rats were made to couple with healthy males fed with normal diet (rice, dried fish, green) and pregnancy was thus repeated in order to obtain youngs in different series. Of the newborns were examined, the body weight, the number of the same litter, histological and roentgenological findings of the bones, chemical analysis of calcium and elementary phosphorous in the bones etc. As the contrast healthy normal youngs were examined at the same time, On the other hand, the youngs of the experiment as well as of the contrast were fed with the rachitic diet from the beginning of the third week after birth and in a long duration of ten or fifteen weeks roentgenological and histological examinations were carried out at different times for the purpose of ascertaining the eruption of rachitic symptomes. The results of the experiment are summarized as follows: 1) During the experiment, the animals lost sometimes the gloss of the fur and became rough-furred. When pregnancy and delivery was repeated, the fur was pulled out to a large extent. The sexual cycle remained regular for a comparatively long time, but it ceased finally, if pregnancy was repeated. 2) By administering the rachitic diet, it was ascertained that the abortion or premature interruption of pregnancy and resorption of intrauterine fetuses took place in a marked degree. The longer the feeding with the rachitic diet, the more marked was this tendency. 3) By feeding with the rachitic diet for a certain time, the animals acquired a condition of low amount of blood phosphorous and symptoms of osteomalacia revealed by roentgen and histoiogical examinations. 4) In the newly born youngs there was no especial change in the body weight, the number of the litter and in the histological findings of the bones, but the amount of calcium in the bones was lowered to a moderate extent. 5) The bodily development of the youngs was general1y bad; those in the experiment being worse than in the contrast, and as time elapsed, the difference became more and more marked. 6) All the Wborns finally acquired the symptoms of rickets; those in the experiment were more rapid in its eruption and more marked in its begree than in the contrast. From the above-results it can be stated that the newborns from the mother fed with the rachitic diet during pregnancy acquired a disposition liable to the rickets or in other words, they were born in a condition of "praerachitis". An antenatal factor was thus revealed to play an important role in the causation of the rickets. en-copyright= kn-copyright= en-aut-name=HasimotoKiyosi en-aut-sei=Hasimoto en-aut-mei=Kiyosi kn-aut-name=橋本清 kn-aut-sei=橋本 kn-aut-mei=清 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學産科婦人科教室 END start-ver=1.4 cd-journal=joma no-vol=55 cd-vols= no-issue=11 article-no= start-page=1455 end-page=1459 dt-received= dt-revised= dt-accepted= dt-pub-year=1943 dt-pub=19431130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studien über die experimentelle Arteriosklerose. (V. Mitteilung.) Über die Blutkalziummenge des Kaninchens vom experimentellen Hochdruck kn-title=實驗的動脈硬變症ニ關スル研究（第5編）實驗的血壓上昇家兎ニ於ケル血中Caliumノ消長ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Der Blutdruckanstieg im oberen Körperteil durch die Fliehkraft kranialwärts senkt den Serumkalziumgehalt sowohl bei normalena als auch bei splanchnektenaiertem Kamimebem. Dagegen vermehrt die Fliehkraft kaudalwärts den Kalziumgehalt. en-copyright= kn-copyright= en-aut-name=HasimotoAkira en-aut-sei=Hasimoto en-aut-mei=Akira kn-aut-name=橋本明 kn-aut-sei=橋本 kn-aut-mei=明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學生理學教室 END start-ver=1.4 cd-journal=joma no-vol=55 cd-vols= no-issue=11 article-no= start-page=1449 end-page=1455 dt-received= dt-revised= dt-accepted= dt-pub-year=1943 dt-pub=19431130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studien über die experimentelle Arteriosklerose. (IV. Mitteilung.) Einfluss von Adrenalin auf den Kalziumstoffwechsel kn-title=實驗的動脈硬變症ニ關スル研究（第4編）Calcium新陳代謝ニ及ボスAdrenalinノ影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Das Adrenalin ruft die Herabsetzung des Serumkalziumgehaltes sowohl bei normalem als auch bei splanchnektomiertem Kaninchen hervor. Bei Kaninchen, deren Serumkalziumgehalt sich durch die tägliche fortdauernde intravenöse Injektion von Adrenalin merklich verringerte, wurde nachher arteriosklerotisches Bild nachgewiesen. en-copyright= kn-copyright= en-aut-name=HasimotoAkira en-aut-sei=Hasimoto en-aut-mei=Akira kn-aut-name=橋本明 kn-aut-sei=橋本 kn-aut-mei=明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學生理學教室 END start-ver=1.4 cd-journal=joma no-vol=55 cd-vols= no-issue=11 article-no= start-page=1445 end-page=1448 dt-received= dt-revised= dt-accepted= dt-pub-year=1943 dt-pub=19431130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studien über die experimentelle Arteriosklerose. (III. Mitteilung.) Über das Entstehen von Arteriosklerose durch das oxydierten Adrenalin kn-title=雜報實驗的動脈硬變症ニ關スル研究（第3編）酸化セル「アドレナリン」ニ依ル實驗的動脈硬變症ノ成生ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Die intravenöse Injektion von Adrenalin, welches durch Wasserstoffsuperoxyd und Kupfersulfat oxydiert wird und nicht mehr blutdrucksteigernd wirkt, führt keine Arteriosklerose beim Kaninchen herbei. Daraus kann man vermuten, dass die arteriosklerosierende Wirkung von Adrenalin auf seinen pressorischen Faktor zurückzuführen ist. en-copyright= kn-copyright= en-aut-name=HasimotoAkira en-aut-sei=Hasimoto en-aut-mei=Akira kn-aut-name=橋本明 kn-aut-sei=橋本 kn-aut-mei=明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學生理學教室 END start-ver=1.4 cd-journal=joma no-vol=55 cd-vols= no-issue=10 article-no= start-page=1305 end-page=1308 dt-received= dt-revised= dt-accepted= dt-pub-year=1943 dt-pub=19431031 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über den Einfluss des Vitamin C auf Blutdrucksteigerung durch Adrenalin kn-title=實驗的動脈硬變症ニ關スル研究（第2編）「アドレナリン」血壓上昇ニ及ボス「ヴイタミンC」ノ影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Neulich gab Herr M. Kanahara in Korea an, dass das Vitamin C Adrenalin -Sklerose vorbeugt. Indem der Verfasser diese Tatsache bestätigte, schritt er weiter vor, die Wirkungsweise von Vitamin C klar zu machen. Die Resultate sind folgendermassen: 1) Bei intravenöser Injektion der Dosen von 1.0, 5.0, 10.0, 25.0, 50.0mg/kg 1- Ascorbinsäure ist keine Veränderung des Blutdrucks bemerkbar. 2) 2 Minuten nach 50mg/kg 1-Ascorbinsäureinjektion eingespritztes Adrenalin von 0.005mg/kg wirkt eben so gut auf Blutdruck wie ohne 1-Ascorbinsäure. 3) Bei intravenöser Injektion der gemischten Lösung von 0.005mg/kg Adrenalin und 50mg/kg 1-Ascorbinsaüre ist keine Veränderung im Vergleich mit dem ungemischten Adrenalinversuch nach weissbar. en-copyright= kn-copyright= en-aut-name=HasimotoAkira en-aut-sei=Hasimoto en-aut-mei=Akira kn-aut-name=橋本明 kn-aut-sei=橋本 kn-aut-mei=明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學生理學教室 END start-ver=1.4 cd-journal=joma no-vol=55 cd-vols= no-issue=10 article-no= start-page=1293 end-page=1304 dt-received= dt-revised= dt-accepted= dt-pub-year=1943 dt-pub=19431031 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Über den Einfluss des Vitamin C auf die experimentelle Arteriosklerose, die durch Adrenalin hervorgerufen werden kann kn-title=實驗的動脈硬變症ニ關スル研究（第1編）「アドレナリン」動脈硬變症ニ及ボス「ヴイタミンC」ノ影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Verfasser untersuchte über Schutz-und Heilwirkung des Vitamin C auf die experimentelle Arteriosklerose durch Adrenalin. Als Versuchstiere wurde männliche Kaninchen (ca 2000g Körpergewicht) gebraucht, an denen die experimentelle Arteriosklerose durch intravenöse Adrenalininjektion erzeugt wurde. Die Resultate sind folgendermassen: 1) Bei der intravenösen Injektion des Adrenaline (hindurch 6 Wochen 0, 2cc täglich) ergibt es schwere sklerotische Veränderung der Aorta. 2) Die gleichzeitige Injektion des Vitamin C mit Adrenalin zeigt nach 6 Wochen keine Veränderung an den Gefässwänden, d.h. Vitamin C wirkt auf die Entstehung der Gefassveranderung prophylaktisch. 3) Die durch Adrenalin hervorgerufene Arteriosklerose wird durch die nachfolgende Vitamin-C-injektion zurückgebildet. en-copyright= kn-copyright= en-aut-name=HasimotoAkira en-aut-sei=Hasimoto en-aut-mei=Akira kn-aut-name=橋本明 kn-aut-sei=橋本 kn-aut-mei=明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學生理學教室 END start-ver=1.4 cd-journal=joma no-vol=56 cd-vols= no-issue=6 article-no= start-page=872 end-page=876 dt-received= dt-revised= dt-accepted= dt-pub-year=1944 dt-pub=19440630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Vitamin B(2)ノAdrenalin血壓上昇ニ及ボス影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=橋本明 kn-aut-sei=橋本 kn-aut-mei=明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學生理學教室 END start-ver=1.4 cd-journal=joma no-vol=65 cd-vols= no-issue=3 article-no= start-page=361 end-page=366 dt-received= dt-revised= dt-accepted= dt-pub-year=1953 dt-pub=19530331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=橋本氏病の一剖檢例 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=大森武士 kn-aut-sei=大森 kn-aut-mei=武士 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=赤木孝 kn-aut-sei=赤木 kn-aut-mei=孝 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=2 en-affil= kn-affil=岡山市巖井三門病院 END start-ver=1.4 cd-journal=joma no-vol=1 cd-vols= no-issue=3-4 article-no= start-page=63 end-page=89 dt-received= dt-revised= dt-accepted= dt-pub-year=1970 dt-pub=19700331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Capital Concentration Ratio and its Significance kn-title=資本集中度とその経済的意味 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoY. en-aut-sei=Hashimoto en-aut-mei=Y. kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue=1 article-no= start-page=41 end-page=59 dt-received= dt-revised= dt-accepted= dt-pub-year=1970 dt-pub=19700630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Chamberlin on the Monopolistic Competition Theory kn-title=チェンバリンを中心とした独占理論（I） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoY. en-aut-sei=Hashimoto en-aut-mei=Y. kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=3 cd-vols= no-issue=1 article-no= start-page=88 end-page=120 dt-received= dt-revised= dt-accepted= dt-pub-year=1971 dt-pub=19710630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Chamberlin on the Monopolistic Competition Theory kn-title=チェンバリンを中心とした独占理論（II） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoY. en-aut-sei=Hashimoto en-aut-mei=Y. kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=4 cd-vols= no-issue=2 article-no= start-page=58 end-page=100 dt-received= dt-revised= dt-accepted= dt-pub-year=1972 dt-pub=19721115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Chamberlin on the Monopolistic Competition Theory kn-title=チェンバリンを中心とした独占理論（III） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoY. en-aut-sei=Hashimoto en-aut-mei=Y. kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue=3-4 article-no= start-page=104 end-page=118 dt-received= dt-revised= dt-accepted= dt-pub-year=1975 dt-pub=19750315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=On the Arrow's Theory of Organization kn-title=K. J. アローの組織論 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoY. en-aut-sei=Hashimoto en-aut-mei=Y. kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue=4 article-no= start-page=205 end-page=209 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19790225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=S. Yamamoto, International Economics kn-title=山本新一著 「国際経済論」 税務経理協会　昭和52年9月刊 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoH. en-aut-sei=Hashimoto en-aut-mei=H. kn-aut-name=橋本博之 kn-aut-sei=橋本 kn-aut-mei=博之 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=13 cd-vols= no-issue=1 article-no= start-page=277 end-page=285 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19810531 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=S. Takeshita, Megalopolis-oriented Regional Development kn-title=竹下昌三著 『地域開発と地方都市』 風間書房 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoTouru en-aut-sei=Hashimoto en-aut-mei=Touru kn-aut-name=橋本徹 kn-aut-sei=橋本 kn-aut-mei=徹 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=関西学院大学 END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=1 article-no= start-page=25 end-page=43 dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19820630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Theory on the Evolutional Process of Economic Area kn-title=経済圏の形成・発展・衰退過程に関する一試論 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoYoshizo en-aut-sei=Hashimoto en-aut-mei=Yoshizo kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=17 cd-vols= no-issue=3-4 article-no= start-page=213 end-page=234 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19860228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Definition of Service and Its Some Implications kn-title=サービスの定義と若干のインプリケーションについて en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoYoshizo en-aut-sei=Hashimoto en-aut-mei=Yoshizo kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=19 cd-vols= no-issue=3-4 article-no= start-page=183 end-page=199 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=19880120 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Outline of Movement toward a Service Economy in Okayama kn-title=岡山県内のサービス経済化の概要 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoYoshizo en-aut-sei=Hashimoto en-aut-mei=Yoshizo kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=22 cd-vols= no-issue=3-4 article-no= start-page=1 end-page=16 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19910226 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Trade in Services: Liberalization and Current Issues kn-title=サービス貿易自由化の問題点 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoHiroyuki en-aut-sei=Hashimoto en-aut-mei=Hiroyuki kn-aut-name=橋本博之 kn-aut-sei=橋本 kn-aut-mei=博之 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=茨城大学人文学部 END start-ver=1.4 cd-journal=joma no-vol=23 cd-vols= no-issue=3 article-no= start-page=51 end-page=69 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19911216 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Organizations and Problems in the Reform of Firms in China (II) kn-title=改革途上の中国企業の組織と問題点（下） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoYoshizo en-aut-sei=Hashimoto en-aut-mei=Yoshizo kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= en-aut-name=ZhangKe en-aut-sei=Zhang en-aut-mei=Ke kn-aut-name=張克 kn-aut-sei=張 kn-aut-mei=克 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil= affil-num=2 en-affil= kn-affil=中国大連理工大学管理学院 END start-ver=1.4 cd-journal=joma no-vol=23 cd-vols= no-issue=2 article-no= start-page=61 end-page=76 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19911016 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Organizations and Problems in the Reform of Firms in China (1) kn-title=改革途上の中国企業の組織と問題点（上） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoYoshizo en-aut-sei=Hashimoto en-aut-mei=Yoshizo kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= en-aut-name=ZhangKe en-aut-sei=Zhang en-aut-mei=Ke kn-aut-name=張克 kn-aut-sei=張 kn-aut-mei=克 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil= affil-num=2 en-affil= kn-affil=中国大連理工大学管理学院 END start-ver=1.4 cd-journal=joma no-vol=24 cd-vols= no-issue=4 article-no= start-page=215 end-page=230 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=On "The Seto Ohashi Bridge and Regional Economic Environmental Problems" edited by Prof. C. Sakamoto and Prof. R. Nakamura kn-title=坂本忠次・中村良平編著 『瀬戸大橋と地域経済・環境問題』 （山陽新聞社刊．pp．239．1992年3月25日）―瀬戸大橋架橋の社会経済的影響に関する包括的な総括への接近― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoRyoichi en-aut-sei=Hashimoto en-aut-mei=Ryoichi kn-aut-name=橋本了一 kn-aut-sei=橋本 kn-aut-mei=了一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=四国学院大学 END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=4 article-no= start-page=451 end-page=461 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940310 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=On Education of Economics in the Faculty of Education kn-title=教育学部における経済学教育の特質に関する一考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoMasaru en-aut-sei=Hashimoto en-aut-mei=Masaru kn-aut-name=橋本勝 kn-aut-sei=橋本 kn-aut-mei=勝 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=4 article-no= start-page=121 end-page=136 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940310 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Austrian Individualistic Subjectivism and Reconsideration of Rationality Concept kn-title=オーストリア学派の個人主義的主観主義と合理性概念の再検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoYoshizo en-aut-sei=Hashimoto en-aut-mei=Yoshizo kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue=2 article-no= start-page=239 end-page=242 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960828 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Age of Urban Choice kn-title=中村良平　著 『いま都市が選ばれる―競争と連携の時代へ―』 （山陽新聞社） 1995年11月　pp．245 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoYoshizō en-aut-sei=Hashimoto en-aut-mei=Yoshizō kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=29 cd-vols= no-issue=4 article-no= start-page=133 end-page=144 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A. Montanari, C. Sakamoto, S. Suzuki, R. Hashimoto, 1997 "The Assessment and Problems of Big Projects" kn-title=A・モソタナーリ／坂本忠次／鈴木茂／橋本了一編著 『大型プロジェクトの評価と課題』（晃洋書房，1997年） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamadaAkira en-aut-sei=Yamada en-aut-mei=Akira kn-aut-name=山田明 kn-aut-sei=山田 kn-aut-mei=明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=名古屋市立大学 END start-ver=1.4 cd-journal=joma no-vol=30 cd-vols= no-issue=3 article-no= start-page=1 end-page=23 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990310 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Structural Changes of Industry and Employment in Japan kn-title=日本産業の構造変革と雇用動向 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The Japanese industry is in a huge whirlpool. Various common senses and conventions have been seriously doubted. Nevertheless, Japan cannot yet find any exit. Even if finding it, she has spent only a time in vain without doing any effectives measure, because most of those are conflict with vested interests or conventional practices. In this paper, I will make a positive analysis of changing industry in Japan after the babble boom crash in 1991 by using Firms and Establishments Census Data and others. Then, I will make it clear that the cause of failure to buoy up her economy consists in a fact that shortage of investment opportunities in her economy has been misunderstood simply as shortage of macro effective demand. Then, comparing the structural adjustment in the first half of the 1990s with one in the second half of the 1970s, I will clarify that the most serious weak point of Japanese-styled management, which has virtually excluded rights of shareholders from their decisions, have got revealed as her economy matures. I will also say that improvement of profitability by making employment fluid is not only effective as a counter-policy to the prolonged structural depression in the open economy but also inescapable in the "affiuent" economy driven by the service industry. Lastly, in place of a conclusion, I will remind a brief summary and lessons of the US and the UK policy experiences after the 1970s. en-copyright= kn-copyright= en-aut-name=HashimotoYoshizo en-aut-sei=Hashimoto en-aut-mei=Yoshizo kn-aut-name=橋本介三 kn-aut-sei=橋本 kn-aut-mei=介三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=大阪大学 END start-ver=1.4 cd-journal=joma no-vol=101 cd-vols= no-issue=11-12 article-no= start-page=1075 end-page=1079 dt-received= dt-revised= dt-accepted= dt-pub-year=1989 dt-pub=198912 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of beautiful bone scan due to bone metastasis of gastric cancer kn-title=Beautiful Bone Scanを呈した胃癌骨転移の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 46-year-old female presented with lumbago. A plain X-ray examination did not indicate any distinctive changes, however a bone scintigram showed beautiful bone scan. A bone marrow biopsy certified metastatic adenocarcinoma and a primary gastric carcinoma was discovered subsequently. Beautiful bone scan can be seen in malignant metastasis, several bone metabolic diseases and other rare cases. A rare case of a gastric cancer exhibiting a beautiful bone scan, is described. en-copyright= kn-copyright= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name=黒田昌宏 kn-aut-sei=黒田 kn-aut-mei=昌宏 aut-affil-num=1 ORCID= en-aut-name=TanakaAkio en-aut-sei=Tanaka en-aut-mei=Akio kn-aut-name=田中朗雄 kn-aut-sei=田中 kn-aut-mei=朗雄 aut-affil-num=2 ORCID= en-aut-name=YamamotoYoshio en-aut-sei=Yamamoto en-aut-mei=Yoshio kn-aut-name=山本淑雄 kn-aut-sei=山本 kn-aut-mei=淑雄 aut-affil-num=3 ORCID= en-aut-name=SimizuMitsuharu en-aut-sei=Simizu en-aut-mei=Mitsuharu kn-aut-name=清水光春 kn-aut-sei=清水 kn-aut-mei=光春 aut-affil-num=4 ORCID= en-aut-name=SatoNobuo en-aut-sei=Sato en-aut-mei=Nobuo kn-aut-name=佐藤伸夫 kn-aut-sei=佐藤 kn-aut-mei=伸夫 aut-affil-num=5 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=6 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=7 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=8 ORCID= en-aut-name=NakadaHiroyuki en-aut-sei=Nakada en-aut-mei=Hiroyuki kn-aut-name=仲田浩之 kn-aut-sei=仲田 kn-aut-mei=浩之 aut-affil-num=9 ORCID= en-aut-name=KibataMasayoshi en-aut-sei=Kibata en-aut-mei=Masayoshi kn-aut-name=木畑正義 kn-aut-sei=木畑 kn-aut-mei=正義 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=国立療養所南岡山病院内科 affil-num=10 en-affil= kn-affil=国立療養所南岡山病院内科 en-keyword=Beautiful Bone Scan kn-keyword=Beautiful Bone Scan en-keyword=胃癌 kn-keyword=胃癌 en-keyword=骨転移 kn-keyword=骨転移 en-keyword=播種性骨髄癌症 kn-keyword=播種性骨髄癌症 END start-ver=1.4 cd-journal=joma no-vol=122 cd-vols= no-issue=3 article-no= start-page=203 end-page=208 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20101201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Development of novel detecting systems and therapies for micro cancer using replication-competent oncolytic adenovirus kn-title=制限増殖型アデノウイルス製剤を用いた新たな微小がん病変の検出法の開発と治療への応用 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KojimaToru en-aut-sei=Kojima en-aut-mei=Toru kn-aut-name=児島亨 kn-aut-sei=児島 kn-aut-mei=亨 aut-affil-num=1 ORCID= en-aut-name=HashimotoYuuri en-aut-sei=Hashimoto en-aut-mei=Yuuri kn-aut-name=橋本悠里 kn-aut-sei=橋本 kn-aut-mei=悠里 aut-affil-num=2 ORCID= en-aut-name=KagawaShunsuke en-aut-sei=Kagawa en-aut-mei=Shunsuke kn-aut-name=香川俊輔 kn-aut-sei=香川 kn-aut-mei=俊輔 aut-affil-num=3 ORCID= en-aut-name=TanakaNoriaki en-aut-sei=Tanaka en-aut-mei=Noriaki kn-aut-name=田中紀章 kn-aut-sei=田中 kn-aut-mei=紀章 aut-affil-num=4 ORCID= en-aut-name=UrataYasuo en-aut-sei=Urata en-aut-mei=Yasuo kn-aut-name=浦田泰生 kn-aut-sei=浦田 kn-aut-mei=泰生 aut-affil-num=5 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name=藤原俊義 kn-aut-sei=藤原 kn-aut-mei=俊義 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 affil-num=5 en-affil= kn-affil=オンコリスバイオファーマ affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 en-keyword=telomerase kn-keyword=telomerase en-keyword=oncolytic adenovirus kn-keyword=oncolytic adenovirus en-keyword=GFP kn-keyword=GFP en-keyword=micrometastasis kn-keyword=micrometastasis en-keyword=circulating tumor cell kn-keyword=circulating tumor cell END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=津島岡大遺跡 4　―第5次調査―　（大学院自然科学研究科棟新営予定地） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=阿部芳郎 kn-aut-sei=阿部 kn-aut-mei=芳郎 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=山本悦世 kn-aut-sei=山本 kn-aut-mei=悦世 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=富樫孝志 kn-aut-sei=富樫 kn-aut-mei=孝志 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=河西学 kn-aut-sei=河西 kn-aut-mei=学 aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=藤原宏志 kn-aut-sei=藤原 kn-aut-mei=宏志 aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=松谷暁子 kn-aut-sei=松谷 kn-aut-mei=暁子 aut-affil-num=6 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=沖陽子 kn-aut-sei=沖 kn-aut-mei=陽子 aut-affil-num=7 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=橋本雄一 kn-aut-sei=橋本 kn-aut-mei=雄一 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil= affil-num=2 en-affil= kn-affil= affil-num=3 en-affil= kn-affil= affil-num=4 en-affil= kn-affil= affil-num=5 en-affil= kn-affil= affil-num=6 en-affil= kn-affil= affil-num=7 en-affil= kn-affil= affil-num=8 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue= article-no= start-page=24 end-page=29 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=199106 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=実験動物の出生前医学における役割 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TanakaOsamu en-aut-sei=Tanaka en-aut-mei=Osamu kn-aut-name=田中修 kn-aut-sei=田中 kn-aut-mei=修 aut-affil-num=1 ORCID= en-aut-name=HashimotoRyuju en-aut-sei=Hashimoto en-aut-mei=Ryuju kn-aut-name=橋本龍樹 kn-aut-sei=橋本 kn-aut-mei=龍樹 aut-affil-num=2 ORCID= en-aut-name=TatewakiReiko en-aut-sei=Tatewaki en-aut-mei=Reiko kn-aut-name=帯刀禮子 kn-aut-sei=帯刀 kn-aut-mei=禮子 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=島根医科大学第一解剖学教室 affil-num=2 en-affil= kn-affil=島根医科大学第一解剖学教室 affil-num=3 en-affil= kn-affil=島根医科大学生物学教室 END start-ver=1.4 cd-journal=joma no-vol=17 cd-vols= no-issue= article-no= start-page=31 end-page=37 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19951220 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Informationized Society and Statistics Environment kn-title=情報化社会と統計環境 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Study of statistics environment has been mainly done by the statistics seminar in the faculty of economics of Kyushu University since 1978. Participants of this study consider this problem as the consciousness of the inhabitants which they call statistical mind. However I think this problem is more complicated than their analysis. I would like to propose to consider statistics environment from various view points; statistics organization, the law or system related to statistics, circumstances of using statistics, and so on. Such consideration may bring us the difficulty to lead the simple conclusion. But this problem cannot be solved by the simple analysis. If we leave this, in the long run we will get the serious social disadvantage. en-copyright= kn-copyright= en-aut-name=HashimotoMasaru en-aut-sei=Hashimoto en-aut-mei=Masaru kn-aut-name=橋本勝 kn-aut-sei=橋本 kn-aut-mei=勝 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学教育学部 END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue= article-no= start-page=28 end-page=32 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=200309 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Possibilities of Weak Acid Hypochlorous Water for Hygiene Control in the Laboratory Animal Facilities - Practical Use as a Substitution for Formaldehyde Fumigation - Application for Sewage Disposal System ofAnimal Facilities - kn-title=弱敵性次亜塩素酸水を用いた動物実験施設での衛生管理の可能性―ホルマリン燻蒸に替わる新たな消毒資材としての活用飼育　汚物排水の消毒処理への応用の可能性― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamashitaKouji en-aut-sei=Yamashita en-aut-mei=Kouji kn-aut-name=山下光治 kn-aut-sei=山下 kn-aut-mei=光治 aut-affil-num=1 ORCID= en-aut-name=MiyakeMana en-aut-sei=Miyake en-aut-mei=Mana kn-aut-name=三宅真名 kn-aut-sei=三宅 kn-aut-mei=真名 aut-affil-num=2 ORCID= en-aut-name=OnoTomoko en-aut-sei=Ono en-aut-mei=Tomoko kn-aut-name=小野朋子 kn-aut-sei=小野 kn-aut-mei=朋子 aut-affil-num=3 ORCID= en-aut-name=NasuHaruaki en-aut-sei=Nasu en-aut-mei=Haruaki kn-aut-name=那須玄明 kn-aut-sei=那須 kn-aut-mei=玄明 aut-affil-num=4 ORCID= en-aut-name=ShigemotoMasayuki en-aut-sei=Shigemoto en-aut-mei=Masayuki kn-aut-name=重本雅之 kn-aut-sei=重本 kn-aut-mei=雅之 aut-affil-num=5 ORCID= en-aut-name=HashimotoHaruo en-aut-sei=Hashimoto en-aut-mei=Haruo kn-aut-name=橋本晴夫 kn-aut-sei=橋本 kn-aut-mei=晴夫 aut-affil-num=6 ORCID= en-aut-name=MasudaMotoi en-aut-sei=Masuda en-aut-mei=Motoi kn-aut-name=増田礎 kn-aut-sei=増田 kn-aut-mei=礎 aut-affil-num=7 ORCID= en-aut-name=NakayamaEiji en-aut-sei=Nakayama en-aut-mei=Eiji kn-aut-name=中山英治 kn-aut-sei=中山 kn-aut-mei=英治 aut-affil-num=8 ORCID= en-aut-name=KurabayashiYuzuru en-aut-sei=Kurabayashi en-aut-mei=Yuzuru kn-aut-name=倉林譲 kn-aut-sei=倉林 kn-aut-mei=譲 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=株式会社エイチ･エス･ピー技術開発部 affil-num=2 en-affil= kn-affil=株式会社エイチ･エス･ピー技術開発部 affil-num=3 en-affil= kn-affil=株式会社エイチ･エス･ピー技術開発部 affil-num=4 en-affil= kn-affil=株式会社エイチ･エス･ピー技術開発部 affil-num=5 en-affil= kn-affil=株式会社エイチ･エス･ピー技術開発部 affil-num=6 en-affil= kn-affil=株式会社エイチ･エス･ピー技術開発部 affil-num=7 en-affil= kn-affil=株式会社エイチ･エス･ピー技術開発部 affil-num=8 en-affil= kn-affil=福田種鶏場株式会社 affil-num=9 en-affil= kn-affil=岡山大学自然生命科学研究支援センター動物資源部門 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=7 article-no= start-page=2547 end-page=2552 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580731 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Comparative Study on the Action of Aureomycin and Terramycin kn-title=微生物に対するオーレオマイシンとテラマイシンの作用の比較 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Both of aureomycin and terramycin belong to the tetracycline, and their action has been considered to be nearly the same. The authors made a comparative study on the action of aureomycin and terramycin and obtained the following results: 1) The respiration of Escherichia coli in the presence of glucose, pyruvate, aspartate and glutamate is markedly inhibited by both of aureomycin and terramycin. The respiration inhibitory action of aureomycin is quantitatively about 3 times higher than that of terramycin. 2) The respiration of Micrococcus pyogenes var. aureus (Terashima) in the presence of glutamate, alanine, pyruvate and lactate is inhibited by both of aureomycin and terramycin. As for the respiration inhibitory action, aureomycin is quantitatively about 3 times stronger than terramycin. 3) The respiration of M. pyogenes var. sureus (Terashima) in the presence of glucose is not inhibited by aureomycin or terramycin, but is rather accelerated by these, particularly by terramycin. 4) As for the growth inhibitory action, aureomycin is somewnat stronger than terramycin. en-copyright= kn-copyright= en-aut-name=YabeYoshiro en-aut-sei=Yabe en-aut-mei=Yoshiro kn-aut-name=矢部芳郎 kn-aut-sei=矢部 kn-aut-mei=芳郎 aut-affil-num=1 ORCID= en-aut-name=NakayamaGoro en-aut-sei=Nakayama en-aut-mei=Goro kn-aut-name=中山五郎 kn-aut-sei=中山 kn-aut-mei=五郎 aut-affil-num=2 ORCID= en-aut-name=HayashiSei en-aut-sei=Hayashi en-aut-mei=Sei kn-aut-name=林生 kn-aut-sei=林 kn-aut-mei=生 aut-affil-num=3 ORCID= en-aut-name=HashimotoRyohei en-aut-sei=Hashimoto en-aut-mei=Ryohei kn-aut-name=橋本良平 kn-aut-sei=橋本 kn-aut-mei=良平 aut-affil-num=4 ORCID= en-aut-name=OnoShigetada en-aut-sei=Ono en-aut-mei=Shigetada kn-aut-name=小野繁忠 kn-aut-sei=小野 kn-aut-mei=繁忠 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部微生物学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部微生物学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部微生物学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部微生物学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部微生物学教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=7 article-no= start-page=2307 end-page=2320 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=1958 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Virus of Infectious Hepatitis in Okayama Prefecture Ⅰ: Purification of the Isolated Virus Ⅱ: Electron Microscopic Study on the Isolated Virus kn-title=岡山県下に発生した流行性肝炎の病原体に関する研究 i) 分離ウイルスの精製 ii) 分離ウイルスの電子顕微鏡的観察 en-subtitle= kn-subtitle= en-abstract=Purification and electron microscopic study of the virus isolated by Murakami et al. from the patients of infectious hepatitis in Okayama Prefecture were tried in parallel with animal experiments. The results are summarized as follows: 1) Of all the purification methods tried, the combination of infusion with a saline solution and centrifugation was proved to be the most excellent one for electron microscopic observation and animal experiments. The good efficiency and the simplicity of its procedures also made this method suitable for the purification of the virus of infectious hepatitis. 2) In electron micrographs, the viruses were observed as round or ovoid particles of abo t 50 mμ in diameter. 3) Inoculation of the material containing these particles into mice caused such pathological findings as previously reported by Murakami at el.; a high degree of degeneration or necrosis of liver parenchymal cells accompanied with various cell infiltrations. These observations led the author to the conclusion that the purified particles were nothing but the isolated hepatotropic viruses. kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoRyohei en-aut-sei=Hashimoto en-aut-mei=Ryohei kn-aut-name=橋本良平 kn-aut-sei=橋本 kn-aut-mei=良平 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=2 article-no= start-page=399 end-page=411 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Srudies on the Influences of Irradiation upon the Bone Marrow Tissue Culture of Rabbits Part Ⅲ. Influences of X-Ray on the Bone Marrow Tissue of Rabbit in Fluid Medium kn-title=放射線の家兎骨髄体外組織培養に及ぼす影響に関する研究 第3編 「レ」線の家兎骨髄体外液体培養に及ぼす影響に就て en-subtitle= kn-subtitle= en-abstract= kn-abstract=Using adult rabbits, the author performed the bone-marrow tissue cultures in fluid medium from the rabbits irradiated repeatedly and systemically with 100r of X-ray irradiation, 24-42 times; 300r, 10 times; and 1,000r once only and observed for the periods of 1-30 days; and obtained the following results. 1) In the group repeatedly irradiated wiht 100r X-ray, both the rate of increase of erythrocyte count as well as that of hemoglobin count decreased markedly. 2) In the group subjected to the irradiation of 3000r, the rate of erythrocyte count and that of hemoglobin count likewise decreased markedly. 3) In the group receiving a single irradiation of 1,000r, the rate of erythrocyte count and that of hemoglbin count decreased gradually along with the lapse of time, and both values reached their minimum on the tenth day while by the thirtieth day both were found to be at the normal. 4) In the repeated irradiations as mentioned above, the erythropoietic function is disturbed in parallel with the function of hemoglobin synthesis, whereas in the group subjected to a single irraiation of 1,000r X-ray, the erythropoietic function seems to be affected more markedly than the function of hemoglbin synthesis. Therefore, in the case receiving smaller doses it is assumed that the erythropoietic function is affected prior to the function of hemoglobin synthesis. en-copyright= kn-copyright= en-aut-name=HashimotoSeishi en-aut-sei=Hashimoto en-aut-mei=Seishi kn-aut-name=橋本誠志 kn-aut-sei=橋本 kn-aut-mei=誠志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=2 article-no= start-page=383 end-page=397 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Influences of Irradiation upon the Bone Marrow Tissue Culture of Rabbits Part Ⅱ. Influences of Radio Isotope P(32) on the Bone Marrow Tissue Culture of Rabbits in Coverslips kn-title=放射線の家兎骨髄体外組織培養に及ぼす影響に関する研究 第2編 放射性同位元素P(32)の家兎骨髄体外被覆培養に及ぼす影響に就て en-subtitle= kn-subtitle= en-abstract= kn-abstract=By injecting 3 mc/kg of radio isotope P(32) once only and observed for the periods of 1-14 days and to other group 800 μc/kg once and observing for the periods of 1-30 days, the author performed cultures of the bone marrow from these rabbits in coverslips and obtained the following results. 1) In the group irradiated with P(32) 3 mc/kg, the relative growth rate, cell density and the wandering velocity of pseudoeosinophils all decreased strikingly; while in the group receiving P(32) 800 μc/kg, these values were found all increased. Namely, in the case receiving a large dosage of P(32) irradiation, the white corpuscle series of the bone marrow show marked disturbances while in the case subjected to a small dosage of the irradiation it is stimulated. 2) The increase in the cell proliferation in the case irradiated with such an amount of P(32) as to cause stimulation seems to precede the increase in the cell functions. 3) Therefore, judging these results along with those in report Ⅰ, the cell proliferation seems to be more sensitive to the irradiation than the cell functions. 4) As the cell proliferation tends to be affected prior to the cell functions in the both irradiations so far described, the influences of P(32) irradiation on the bone marrow seem not to differ essentially to any great extent from those of X-ray irradiation. en-copyright= kn-copyright= en-aut-name=HashimotoSeishi en-aut-sei=Hashimoto en-aut-mei=Seishi kn-aut-name=橋本誠志 kn-aut-sei=橋本 kn-aut-mei=誠志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=2 article-no= start-page=369 end-page=381 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Influences of Irradiation upon the Bone Marrow Tissue Culture of Rabbits Part I. Influences of X-Ray on the Bone Marrow Tissue Culture of Rabbits in Coverslips kn-title=放射線の家兎骨髄体外組織培養に及ぼす影響に関する研究 第1編 「レ」線の家兎骨髄体外被覆培養に及ぼす影響に就て en-subtitle= kn-subtitle= en-abstract= kn-abstract=With the use of adult rabbits, the author performed the bonemarrow culture in coverslips and obtained from the rabbits irradiated repeatedly and systemically with 100r of X-ray 24-41 times, and 300r of X-ray ten times, and 1,000r of X-ray once and observed the bone marrow from respective groups during the periods ranging 1-30 clays after the irradiation. The results are described in the following. 1) In the group receiving repeatedly and systemically the irradiation of 1000r of X-ray the relative growth rate, cell density, the wandering velocity of pseudoeosinophils all decreased markedly. 2) In the group given the irradiation of 300r X-ray, no sign whatsoever could be recognized as regards the relative growth rate, cell density and the wandering velocity of pseudoeosinophils; and the bone marrow presented aplasia. 3) In the group receiving 1,000r of X-ray irradiation once only, the relative growth rate, cell density and the wandering velocity of pseudoeosinophils all docreased gradually lower with the lapse of time; and all the values presented their minimum on the tenth day but on the thirtieth day it was found that they were all rather increased. 4) Of the disturbances in the bone marrow due to the X-ray irradiation. in the groups receiving repeated irradiation the cell proliferation was disturbed in direct proportion to those of the cell function. In the group receiving a single irradiation of 1,000r, the cell proliferation was disturbed on the second day but it seemed to have a tendency to precede the disturbances of the cell functions. Therefore, it is assumed that in the case receiving a small dose of X-ray irradiation the cell proliferation of bone marrow is disturbed earlier, and the cell functions are diminished later. en-copyright= kn-copyright= en-aut-name=HashimotoSeishi en-aut-sei=Hashimoto en-aut-mei=Seishi kn-aut-name=橋本誠志 kn-aut-sei=橋本 kn-aut-mei=誠志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=11-12 article-no= start-page=1001 end-page=1007 dt-received= dt-revised= dt-accepted= dt-pub-year=1963 dt-pub=19631230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Three cases of WPW syndrome kn-title=WPW症候群の三例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Three cases of WPW syndrome were reported. One was A-type and other two were B-type. In one of B-type supraventricular tachycardia was seen In E. K. G.. In another one of B-type, WPW was converted into normal pattern by administration of procaine amide. en-copyright= kn-copyright= en-aut-name=HaraokaSyoichi en-aut-sei=Haraoka en-aut-mei=Syoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=1 ORCID= en-aut-name=HashimotoYasuharu en-aut-sei=Hashimoto en-aut-mei=Yasuharu kn-aut-name=橋本恭治 kn-aut-sei=橋本 kn-aut-mei=恭治 aut-affil-num=2 ORCID= en-aut-name=NukadaKaname en-aut-sei=Nukada en-aut-mei=Kaname kn-aut-name=額田要 kn-aut-sei=額田 kn-aut-mei=要 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=3 article-no= start-page=801 end-page=810 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Epidemiological Observations on Infectious Hepatitis Prevailed in Okayama Prefecture kn-title=岡山県における流行性肝炎の流行に関する検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=6246 infectious hepatitis cases treated at 25 hospitals located in Okayama Prefecture during the last six years, 1952 to 1957, were studied mainly from the epidemiological point of view, and the following results were obtained. 1) Infectious hepatitis has been prevailed all over the prefecture since the initial epidemic in 1951. As the mode of epidemic became protracted, chronic and abortive forms were prone to increase in number. The ratio of total patients to infectious hepatitis cases was 1.27 per cent. 2) Extensive infections among villagers were noted in 73 hamlets, and it was presumed that the epidemic has been prevailed over the whole prefecture taking a hamlet, village or a town as unit. Infections among family were noted in 62 families, however, fnrther detailed study in the epidemic areas might show the higher morbidity. It was not certain whether these infections were entirely family or simultaneous infections. 3) As to seasonal occurence, considerable number of cases had onset of the disease during the period of early summer to early fall. 4) As to age, it has ranged mostly from the second to third decade, rather many in children but not rare in the aged. As to sex, predominant in males in general, but considerable differences were seen among hospitals and times. No definite relationship was noted between the epidemc and sex. 5) Throughout the last six years there have been 38.7 per cent of chronic hepatitis cases. In 41.3 per cent of the whole patients presented jaundice in their clinical courses. The fact that the longer the period of the epidemic the more increase increase in anicteric cases was noted. 6) Two year's follow-up studies after the epidemic, showed 209 of relapsed cases in whom 36.4 per cent were icteric. 7) 110 cases has jaundice, which was thought to be infectious hepatitis, in the past. Some of them were presumably reinfections or superinfections but definite conclusion could not be made. 8) 20 cases of fulminant hepatitis, malignant type of infectious hepatitis, and 6 cases of protracted form were studied. 22 cases of them were fatal. Such severe hepatitis patients were seen mainly in males of the second and third decades. 9) 61 cases (0.98%) developed postnecrotic cirrhosis, and 10 cases of them were fatal. 10) Serum hepatitis was noted in 1.6 per cent of the whole patients seen in Medical Services at 18 hospitals in Okayama Prefecture during the last six years, 1952 to 1957. No definite correlation between the epidemic of infectious hepatitis and outbreak of serum hepatitis was noted. en-copyright= kn-copyright= en-aut-name=KosakaKiyowo en-aut-sei=Kosaka en-aut-mei=Kiyowo kn-aut-name=小坂淳夫 kn-aut-sei=小坂 kn-aut-mei=淳夫 aut-affil-num=1 ORCID= en-aut-name=NagashimaHideo en-aut-sei=Nagashima en-aut-mei=Hideo kn-aut-name=長島秀夫 kn-aut-sei=長島 kn-aut-mei=秀夫 aut-affil-num=2 ORCID= en-aut-name=ShimadaYoshihiro en-aut-sei=Shimada en-aut-mei=Yoshihiro kn-aut-name=島田宜浩 kn-aut-sei=島田 kn-aut-mei=宜浩 aut-affil-num=3 ORCID= en-aut-name=YamabukiTakahiro en-aut-sei=Yamabuki en-aut-mei=Takahiro kn-aut-name=山吹隆寛 kn-aut-sei=山吹 kn-aut-mei=隆寛 aut-affil-num=4 ORCID= en-aut-name=KawaguchiMasamitsu en-aut-sei=Kawaguchi en-aut-mei=Masamitsu kn-aut-name=川口正光 kn-aut-sei=川口 kn-aut-mei=正光 aut-affil-num=5 ORCID= en-aut-name=YamamotoShigeru en-aut-sei=Yamamoto en-aut-mei=Shigeru kn-aut-name=山本繁 kn-aut-sei=山本 kn-aut-mei=繁 aut-affil-num=6 ORCID= en-aut-name=OhtaYasuyuki en-aut-sei=Ohta en-aut-mei=Yasuyuki kn-aut-name=太田康幸 kn-aut-sei=太田 kn-aut-mei=康幸 aut-affil-num=7 ORCID= en-aut-name=UjikeMutsuo en-aut-sei=Ujike en-aut-mei=Mutsuo kn-aut-name=氏家睦夫 kn-aut-sei=氏家 kn-aut-mei=睦夫 aut-affil-num=8 ORCID= en-aut-name=KusakaYoshiro en-aut-sei=Kusaka en-aut-mei=Yoshiro kn-aut-name=草加芳郎 kn-aut-sei=草加 kn-aut-mei=芳郎 aut-affil-num=9 ORCID= en-aut-name=MitsudaToshihiro en-aut-sei=Mitsuda en-aut-mei=Toshihiro kn-aut-name=光田利弘 kn-aut-sei=光田 kn-aut-mei=利弘 aut-affil-num=10 ORCID= en-aut-name=KiharaTsuyoshi en-aut-sei=Kihara en-aut-mei=Tsuyoshi kn-aut-name=木原彊 kn-aut-sei=木原 kn-aut-mei=彊 aut-affil-num=11 ORCID= en-aut-name=KondoTadasuke en-aut-sei=Kondo en-aut-mei=Tadasuke kn-aut-name=近藤忠亮 kn-aut-sei=近藤 kn-aut-mei=忠亮 aut-affil-num=12 ORCID= en-aut-name=HaraokaSyoichi en-aut-sei=Haraoka en-aut-mei=Syoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=13 ORCID= en-aut-name=AmiokaTadashi en-aut-sei=Amioka en-aut-mei=Tadashi kn-aut-name=網岡忠 kn-aut-sei=網岡 kn-aut-mei=忠 aut-affil-num=14 ORCID= en-aut-name=IshimitsuTetsusaburo en-aut-sei=Ishimitsu en-aut-mei=Tetsusaburo kn-aut-name=石光鉄三郎 kn-aut-sei=石光 kn-aut-mei=鉄三郎 aut-affil-num=15 ORCID= en-aut-name=KonoHiroya en-aut-sei=Kono en-aut-mei=Hiroya kn-aut-name=河野浩哉 kn-aut-sei=河野 kn-aut-mei=浩哉 aut-affil-num=16 ORCID= en-aut-name=MitsumotoToshiro en-aut-sei=Mitsumoto en-aut-mei=Toshiro kn-aut-name=光本敏郎 kn-aut-sei=光本 kn-aut-mei=敏郎 aut-affil-num=17 ORCID= en-aut-name=AisakaTadakazu en-aut-sei=Aisaka en-aut-mei=Tadakazu kn-aut-name=相坂忠一 kn-aut-sei=相坂 kn-aut-mei=忠一 aut-affil-num=18 ORCID= en-aut-name=KosakaChuihiro en-aut-sei=Kosaka en-aut-mei=Chuihiro kn-aut-name=小坂忠一郎 kn-aut-sei=小坂 kn-aut-mei=忠一郎 aut-affil-num=19 ORCID= en-aut-name=MoritaniYui en-aut-sei=Moritani en-aut-mei=Yui kn-aut-name=森谷有為 kn-aut-sei=森谷 kn-aut-mei=有為 aut-affil-num=20 ORCID= en-aut-name=TabuchiHiroshi en-aut-sei=Tabuchi en-aut-mei=Hiroshi kn-aut-name=田渊博司 kn-aut-sei=田渊 kn-aut-mei=博司 aut-affil-num=21 ORCID= en-aut-name=HashimotoKyoji en-aut-sei=Hashimoto en-aut-mei=Kyoji kn-aut-name=橋本恭治 kn-aut-sei=橋本 kn-aut-mei=恭治 aut-affil-num=22 ORCID= en-aut-name=KimuraKenichi en-aut-sei=Kimura en-aut-mei=Kenichi kn-aut-name=木村健一 kn-aut-sei=木村 kn-aut-mei=健一 aut-affil-num=23 ORCID= en-aut-name=KonoHiroshi en-aut-sei=Kono en-aut-mei=Hiroshi kn-aut-name=河野宏 kn-aut-sei=河野 kn-aut-mei=宏 aut-affil-num=24 ORCID= en-aut-name=TamaoHiroyasu en-aut-sei=Tamao en-aut-mei=Hiroyasu kn-aut-name=玉尾博康 kn-aut-sei=玉尾 kn-aut-mei=博康 aut-affil-num=25 ORCID= en-aut-name=HiguchiYosimitsu en-aut-sei=Higuchi en-aut-mei=Yosimitsu kn-aut-name=樋口祥光 kn-aut-sei=樋口 kn-aut-mei=祥光 aut-affil-num=26 ORCID= en-aut-name=YahataKatsumi en-aut-sei=Yahata en-aut-mei=Katsumi kn-aut-name=八幡勝美 kn-aut-sei=八幡 kn-aut-mei=勝美 aut-affil-num=27 ORCID= en-aut-name=ImaiHarujiro en-aut-sei=Imai en-aut-mei=Harujiro kn-aut-name=今井春路郎 kn-aut-sei=今井 kn-aut-mei=春路郎 aut-affil-num=28 ORCID= en-aut-name=KameyamaIchiro en-aut-sei=Kameyama en-aut-mei=Ichiro kn-aut-name=亀山一郎 kn-aut-sei=亀山 kn-aut-mei=一郎 aut-affil-num=29 ORCID= en-aut-name=ArijiSumiro en-aut-sei=Ariji en-aut-mei=Sumiro kn-aut-name=有地澄郎 kn-aut-sei=有地 kn-aut-mei=澄郎 aut-affil-num=30 ORCID= en-aut-name=FujimoriYasuhiko en-aut-sei=Fujimori en-aut-mei=Yasuhiko kn-aut-name=藤森恭彦 kn-aut-sei=藤森 kn-aut-mei=恭彦 aut-affil-num=31 ORCID= en-aut-name=NakagawaSyoso en-aut-sei=Nakagawa en-aut-mei=Syoso kn-aut-name=中川昌壮 kn-aut-sei=中川 kn-aut-mei=昌壮 aut-affil-num=32 ORCID= en-aut-name=HiranoYutaka en-aut-sei=Hirano en-aut-mei=Yutaka kn-aut-name=平野寛 kn-aut-sei=平野 kn-aut-mei=寛 aut-affil-num=33 ORCID= en-aut-name=KobayashiToshinari en-aut-sei=Kobayashi en-aut-mei=Toshinari kn-aut-name=小林敏成 kn-aut-sei=小林 kn-aut-mei=敏成 aut-affil-num=34 ORCID= en-aut-name=SeidoIchiro en-aut-sei=Seido en-aut-mei=Ichiro kn-aut-name=清藤一郎 kn-aut-sei=清藤 kn-aut-mei=一郎 aut-affil-num=35 ORCID= en-aut-name=TanabeIsao en-aut-sei=Tanabe en-aut-mei=Isao kn-aut-name=田辺功 kn-aut-sei=田辺 kn-aut-mei=功 aut-affil-num=36 ORCID= en-aut-name=TakedaKazuhisa en-aut-sei=Takeda en-aut-mei=Kazuhisa kn-aut-name=武田和久 kn-aut-sei=武田 kn-aut-mei=和久 aut-affil-num=37 ORCID= en-aut-name=HayashiShinichiro en-aut-sei=Hayashi en-aut-mei=Shinichiro kn-aut-name=林愼一郎 kn-aut-sei=林 kn-aut-mei=愼一郎 aut-affil-num=38 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=9 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=10 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=11 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=12 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=13 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=14 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=15 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=16 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=17 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=18 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=19 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=20 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=21 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=22 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=23 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=24 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=25 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=26 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=27 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=28 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=29 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=30 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=31 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=32 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=33 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=34 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=35 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=36 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=37 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=38 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=76 cd-vols= no-issue=10 article-no= start-page=535 end-page=538 dt-received= dt-revised= dt-accepted= dt-pub-year=1964 dt-pub=19641030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effct of ATP on excretion of BSP in liver disease kn-title=肝疾患時のBSP色素排泄に対するALPの効果 en-subtitle= kn-subtitle= en-abstract= kn-abstract=BSP retention and hepatic blood flow were determined after administration of ATP in liver disease, and the following results were obtained. 1) 14 cases out of 22 with liver disease having, administration of ATP improved in BSP retention, and on the other hand, 8 cases of the remainder showed no changes or aggravation in that test. 2) Considerable grade of hepatic cell degeneration or necrosis was found in liver biopsy tissue of the all aggravating cases. 3) After the intravenous injection of ATP hepatic blcod flow decreased temporarily and was followed subsequently by an increase. en-copyright= kn-copyright= en-aut-name=SimadaYosihiro en-aut-sei=Simada en-aut-mei=Yosihiro kn-aut-name=島田宜浩 kn-aut-sei=島田 kn-aut-mei=宜浩 aut-affil-num=1 ORCID= en-aut-name=NambaHideki en-aut-sei=Namba en-aut-mei=Hideki kn-aut-name=難波英樹 kn-aut-sei=難波 kn-aut-mei=英樹 aut-affil-num=2 ORCID= en-aut-name=HasimotoHiroyuki en-aut-sei=Hasimoto en-aut-mei=Hiroyuki kn-aut-name=橋本宏之 kn-aut-sei=橋本 kn-aut-mei=宏之 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=76 cd-vols= no-issue=1-3 article-no= start-page=131 end-page=139 dt-received= dt-revised= dt-accepted= dt-pub-year=1964 dt-pub=19640330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Electrocardiogram in Liver Disease Part 1. Electrocardiogrdiogram in Liver Disease kn-title=肝疾患の心電図に関する研究 第1編 肝疾患の心電図 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Electrocardiograms in 120 patients of liver disease (39 acute hepatitis, 39 chronic hepatitis, 32 liver cirrhosis and 10 liver cancer) were studied. 1) Pathologic findings in EKG were flatening T wave, ST depression, ST-T fusion and disturbance of conducting systems such as Ist. degree A-V block, bundle branch block and notching of R wave. 2) Flatening T wave was found in 44 cases; ST depression in 41 cases; ST-T fusion in 41 cases. They were found more in liver cirrhosis and cancer than in hepatitis. 3) QT interval was slightly prolonged in liver cirrhosis and cancer. 4) QRS interval was prolonged as the disease progressed. 5) magnitude of T wave was correlated to the serum bilirubin, colloidar reaction, BSP and gamma globulin, not to the total protein and A/G. 6) ST-T fusion was correlated to the gamma globulin and the periods of the diseese. 7) No correlation was found between the magnitude of T wave, ST-T fusion and serum electrolites. T/R was, however, slightly correlated to the serum potassium. 8) Magnitude of T wave was increased as the disease became better clinically. en-copyright= kn-copyright= en-aut-name=HashimotoYasuharu en-aut-sei=Hashimoto en-aut-mei=Yasuharu kn-aut-name=橋本恭治 kn-aut-sei=橋本 kn-aut-mei=恭治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=82 cd-vols= no-issue=3-4 article-no= start-page=91 end-page=99 dt-received= dt-revised= dt-accepted= dt-pub-year=1970 dt-pub=19700430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Histochemical studies on the irradiation carcinoma of the uterine cervix kn-title=放射線照射子宮頸癌の組織化学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Histological and histochemical changes of the cervix by irradiation were investigated on 16 cases of carcinoma of the cervix. Maximum surface dose, 2,000-6,000R., was applied to the cervix with a special colpostat followed by radical hysterectomy 1-10 days later. The difference between irradiated areas and non irradiated areas was studied with following results. 1) The activity of non specific esterase increased in irradiated areas with expectation of a useful indicator of radiosensitivity. 2) SDH, LDH and G-6-P DH showed no change in their activity after irradiation. 3) The appeareance of mast cells has some relation with histological radiation effect. Increase of mast cells in number was noticed in good histological response. en-copyright= kn-copyright= en-aut-name=HashimotoTakeo en-aut-sei=Hashimoto en-aut-mei=Takeo kn-aut-name=橋本威郎 kn-aut-sei=橋本 kn-aut-mei=威郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部産科婦人科教室 END start-ver=1.4 cd-journal=joma no-vol=86 cd-vols= no-issue=5-6 article-no= start-page=221 end-page=229 dt-received= dt-revised= dt-accepted= dt-pub-year=1974 dt-pub=19740630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Diagnosis of Pancreatic Diseases by Scintigraphy kn-title=膵臓シンチグラフィーによる膵疾患の診断 en-subtitle= kn-subtitle= en-abstract= kn-abstract=With 63 cases on whom we performed the scintigraphy of pancreatic diseases, we studied the possiblity of differential diagnosis and oter points relevant to the diagnosis in this disease group by comparing retrospectively clinical findings with postoperative findings of these cases, and arrived at the conclusions as follows: 1) For the scintigraphy of pancreas, scinticamera is excellent, and it is especially useful to take consecutive pictures at intervals of 10 minutes each for one hour with this camera after injecting (75)Se-methionine. 2) The major cases of the pancreas that gives normal visualization can be considered as normal, but as normal pictures can be obtained even in the cases of chronic pancreatitis. There are some cases where differential diagnosis between the two disease groups is difficult by scintigraphic finding. 3) In the case of a focal decrease of uptake first of all cancer can be suspected. However, there are cases where differentiation from chronic pancreatitis is difficult. In such instances, about half of the cases demonstrating roentgenologically calcification proves to be of chronic, calcified pancreatitis, but excluding these cases the percentage of cancer cases is high. 4) Among those cases showing pancreas in scintigram faint or nonvisible, there were two cases out of 3 where chronic pancreatitis was complicated with calcification. Excluding the two cases, cancer occupies a decidedly high percentage, and the cancer is mostly located around the head of pancreas, indicating that pathologic changes have invaded main pancreatic ducts. 5) There were 7 cases of chronic, calcified pancreatitis, one case giving normal pancreatitis, one case giving normal scitigraphic findings, 4 cases a focal decrease of uptake, and two cases showing the pancreas faint or nonvisible. en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=1 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=2 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=3 ORCID= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=4 ORCID= en-aut-name=TakagiHisao en-aut-sei=Takagi en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=5 ORCID= en-aut-name=HaisaYoshio en-aut-sei=Haisa en-aut-mei=Yoshio kn-aut-name=羽井佐芳雄 kn-aut-sei=羽井佐 kn-aut-mei=芳雄 aut-affil-num=6 ORCID= en-aut-name=KumadaYasumasa en-aut-sei=Kumada en-aut-mei=Yasumasa kn-aut-name=久万田泰昌 kn-aut-sei=久万田 kn-aut-mei=泰昌 aut-affil-num=7 ORCID= en-aut-name=WakabayashiHiroshi en-aut-sei=Wakabayashi en-aut-mei=Hiroshi kn-aut-name=若林弘 kn-aut-sei=若林 kn-aut-mei=弘 aut-affil-num=8 ORCID= en-aut-name=HashimotoGonosuke en-aut-sei=Hashimoto en-aut-mei=Gonosuke kn-aut-name=橋本郷之介 kn-aut-sei=橋本 kn-aut-mei=郷之介 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=88 cd-vols= no-issue=11-12 article-no= start-page=1093 end-page=1103 dt-received= dt-revised= dt-accepted= dt-pub-year=1976 dt-pub=19761230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cell-mediated immunity in Hashimoto's disease and Basedow's disease Part Ⅰ. Studies on migration inhibition factor (MIF) and lymphocyte blastogenesis with phytohaemagglutinin (PHA) kn-title=橋本病Basedow病患者の細胞性免疫に関する研究 第一編 MIF及びリンパ球芽球化反応の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Cellular hypersensitivity was studied using in vitro lymphocyte transformation technique with PHA and indirect MIF test in 53 patients with Hashimoto's thyroiditis, 29 patients with Basedow's disease and in 16 normal subjects. Lymphocytes were separated from peripheral blood by cotton columns. In the studies of lymphocyte blastgenesis, 2ml of lymphocyte suspension containing 1.5×10(6) cells/ml in TC-199 supplemented with 15% calf serum were cultured with 200μg PHA for 72 hours at 37℃ in an atmosphere containing 95% air and 5% CO2, and blastoid cells were identified by microscopic examinations. For the MIF test, 2ml of 3×10(6) lymphocytes/ml in TC-199 containing appropriate antigens (human thyroid microsome fraction; 100-500μg wet weight/ml, thyroglobulin; 100μg/ml) were cultured at the same circumstances for 72 hours and then the culture supernatants were examined for the migration of guinea-pig peritoneal macrophages. Migration index (M. I.) was a rate of the area of migration in supernatant with antigen to that without antigen.The rate of blastogenesis of lymphocytes in response to PHA was 32.5±11.2% (mean±SD) in 26 patients with Hashimoto's disease, 49.0±7.6% (mean±SD) in 11 patients with Basedow's disease, and 49.0±8.1% in 14 normal subjects. Significant low response to PHA (the rate under 33%, mean-2SD of normal subjects)was recognized in 14 patients (54% ) with Hashimoto's disease. No patient with Basedow's disease showed abnormal response to PHA. Migration index (MI) with thyroid microsomal fraction was 85.6±19.5% in 40 patients with Hashimoto's disease, 96.6±8.2% in 15 patients with Basedow's disease, and 97.6±10.1% in 18 normal subjects. MI under 77.4% (mean-2SD of normal subjects) was recognized in 12 patients (30%) with Hashimoto's disease. But, MIF production against native or denatured thyroglobulin was negative in all patients examined. There was no definite correlation between MIF production in response to thyroid microsomal fraction and antithyroglobulin antibody titer in patients with Hashimoto's disease.But the patients with positive MIF test showed low or negative thyroglobulin antibody in serum. There were no appearant correlations between MIF test, blastogenesis of lymphocytes with PHA and clinical findings such as age, duration of disease, histology and thyroid function. Above results indicated that T-lymphocyte activity or population of T-lymphocytes responding to PHA was decreased in Hashimoto's disease. On the other hand, it was also shown that the population of lymphocytes sensitized against thyroid autoantigens was present in the peripheral circulation of some patients with this disease. Whether they were T-or B-lymphocytes was not conclusive from the present studies. These sensitized lymphocytes might play important roles in the pathogenesis of Hashimoto's thyroiditis. en-copyright= kn-copyright= en-aut-name=TakehisaYoshiaki en-aut-sei=Takehisa en-aut-mei=Yoshiaki kn-aut-name=竹久義明 kn-aut-sei=竹久 kn-aut-mei=義明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第三内科学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=9-10 article-no= start-page=1157 end-page=1163 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19781030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Diagnosis of heart disease using by RI angio cardiography Part Ⅲ. Cases of left to right shunts kn-title=RI Angiocardiographyによる心疾患の診断 第3編 左-右シャント症例について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Count ratio (C(2)/C(1)) technique for detection of left to right shunts by radionuclide was performed. Count ratio technique of ASD cases accurately detected shunts and could reliably separate from normals, but there were a few false positive in patients with ventricle septal defect. There was no correlation between C(2)/C(1) ratio and oximetry. Postoperatively, C(2)/C(1) ratios of ASD cases were resumed to normal or close to normal but some cases of VSD were not returned to normal. en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=1 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=2 ORCID= en-aut-name=KawaseEtsuo en-aut-sei=Kawase en-aut-mei=Etsuo kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=3 ORCID= en-aut-name=TakakiHisao en-aut-sei=Takaki en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=4 ORCID= en-aut-name=MizukawaKiichiro en-aut-sei=Mizukawa en-aut-mei=Kiichiro kn-aut-name=水川帰一郎 kn-aut-sei=水川 kn-aut-mei=帰一郎 aut-affil-num=5 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=6 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=7 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大孝医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=9-10 article-no= start-page=1145 end-page=1149 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19781030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Diagnosis of heart disease using by RI angiocardiography Part Ⅱ. Mitral valve disease kn-title=RI angio-cordiographyによる心疾患の診断 第2編 僧帽弁疾患症例を中心として en-subtitle= kn-subtitle= en-abstract=This report represents an extension of our use of a Scintillation (Anger) camera with computer processing (Toshiba DAP 5000-2) of data for evaluation of mitral valve disease (11 cases). For these studies we have administered 10 mCi of (99m)Tc intravenously and have followed its passage through the heart and lung using techniques for data acquisition: a 35 mm camera, a video tape system for data storage and replay for computer analysis using a DAP 5000-2. RI dilution curves recorded on the right ventricle, the left lung and the left ventricle were analyzed to obtain following parameters, namely interventricular peak to peak time, C(2)/C(1) ratio of each dilution curves. These data showed following: 1) Interventricular peak to peak time normal group (12 cases): 6.40 ± 1.18 seconds mitral valve disease (11 cases): 11.34 ± 3.69 seconds 2) a) C(2)/C(1) ratio of the right ventricle normal group: 0.45 ± 0.08 seconds mitral valve disease: 0.58 ± 0.17 seconds b) C(2)/C(1) ratio of the left ventricle normal group: 0.38 ± 0.09 seconds mitral valve disease: 0.49 ± 0.11 seconds c) C(2)/C(1) ratio of the left lung normal group: 0.45 ± 0.08 seconds mitral valve disease: 0.50 ± 0.12 seconds kn-abstract=心疾患を有する患者では,その循環動態は種々の因子により容易に変化するものであり,一回の検査のみで決して正確にその患者の動態を表わしているとはいいがたい.この点コンピューターを用いたRI angio-cardiography(以下RCGと略す)は被曝線量も少く,生理的状態を損うことなく繰返し検査を行うことが出来る非観血的方法であり,心疾患者の術前術後の変化,治療経過観察に極めて有用である.従って,僧帽弁疾患におけるRCGによる右室,左室peak to peak time C(2)/C(1)比の解折は,上述の点後於て重要な臨床情報を提供すると考えられる.今回は僧帽弁疾患を中心としてこれらの点について若干の検討を試みた. en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=1 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=2 ORCID= en-aut-name=KawaseEtsuo en-aut-sei=Kawase en-aut-mei=Etsuo kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=3 ORCID= en-aut-name=TakakiHisao en-aut-sei=Takaki en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=4 ORCID= en-aut-name=MizukawaKiichiro en-aut-sei=Mizukawa en-aut-mei=Kiichiro kn-aut-name=水川帰一郎 kn-aut-sei=水川 kn-aut-mei=帰一郎 aut-affil-num=5 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=6 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=7 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=8 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=7-8 article-no= start-page=993 end-page=998 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=197808 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Diagnosis of heart disease using by RI angiocardiography Part I. Normal subjects kn-title=RI angio-cardiographyによる心疾患の診断 第一編 正常例の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=This study is to show applicability of RCG and to determine criteria for its use of normals. Instrumentation for data processing was DAP 500-2(Toshiba, Ltd, Tokyo Japan) RI dilution curves recorded an the right ventricle, the left lung, the left ventricle of 12 normal subjects were analyzed to obtain following parameters, namely interventricular peak to peak time and C(2)/C(1) ratio. 1) intraventricular peak to peak time average: 6.40 ± 1.18 seconds (4.80~8.64) 2) C(2)/C(1) ratio of right ventricle average: 0.45 ± 0.08 seconds (0.30~0.59) 3) C(2)/C(1) ratio of left ventricle average: 0.38 ± 0.09 seconds (0.22 ± 0.51) 4) C(2)/C(1) ratio of left lung average: 0.45 ± 0.08 seconds (0.30~0.55) en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=1 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=2 ORCID= en-aut-name=KawaseEtsuo en-aut-sei=Kawase en-aut-mei=Etsuo kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=3 ORCID= en-aut-name=TakakiHisao en-aut-sei=Takaki en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=4 ORCID= en-aut-name=MizukawaKiichiro en-aut-sei=Mizukawa en-aut-mei=Kiichiro kn-aut-name=水川帰一郎 kn-aut-sei=水川 kn-aut-mei=帰一郎 aut-affil-num=5 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=6 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=7 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=8 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=5-6 article-no= start-page=545 end-page=550 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19780630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experiences in the use of ACTA scanner (type 0100) Part 2. Consideration on the use of ACTA scanner kn-title=ACTAスキャナー0100型の使用経験 第2報 CT装置の使用に対する考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We have previously reported an outline of the ACTA scanner and its usefulness. In this report, we intend to present some aspects of the apparatus itself needing improvement and also offer our opinion on some points to be borne in mind on the actual use of the scanner. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=2 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=4 ORCID= en-aut-name=KawaseEtuo en-aut-sei=Kawase en-aut-mei=Etuo kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=5 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=6 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=7 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=5-6 article-no= start-page=537 end-page=543 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19780630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experiences in the use of ACTA scanner (type 0100) Part 1. Consideration on CT scanner kn-title=ACTAスキャナー0100型の使用経験 第1報 CT装置に対する考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is only a little over two odd years since computer tomography (CT) has come to be used in Japan. However, during this short period of time great interest in the CT apparatus has been aroused. As we have had the opportunity to use the ACTA scanner (type 0100) set in June, 1976 at the hospital affiliated to Okayama University, we describe here our experiences with it and introduce an outline of the CT apparatus as well as its usefulness. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=2 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=4 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=5 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=6 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=1-2 article-no= start-page=179 end-page=193 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19780228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cell-mediated immunity in Hashimoto's disease and Basedow's disease Part Ⅱ. Studies on the immunological functions of monocytes and macrophages in patients with Hashimoto's disease kn-title=橋本病・Basedow病患者の細胞性免疫に関する研究 第二編 橋本病における単球・マクロフアージの免疫学的機能とその意義 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In Hashimoto's thyroiditis, not only a profuse lymphocytic infiltration but also macrophages infiltration are seen in the thyroid gland. In this paper, the immunopathological roles of the monocyte-macrophage cell line in Hashimoto's disease was reported. By the histological examination of the thyroid glands from 39 patients with Hashimoto's thyroiditis, infiltrations of macrophages were present in the thyroid follicles of 12 out of 23 patients with diffuse thyroiditis and of 13 out of 16 patients with focal thyroiditis. In these follicles with macrophage infiltrations, acinar cells showed eosinophilic changes characteristic of Hashimoto's thyroiditis and disappearance of follicular colloid. It was not known whether such macrophages were nonspecific scavenger cells or specifically activated cells against thyroid antigens and involved in the immunologically specific tissue destruction in Hashimoto's disease. Whether peripheral monocytes, precursors of tissue macrophages, in patients with Hashimoto's disease have increased ability to bind thyroid specific antigen (thyroglobulin) or not was studied by rosette formation with thyroglobulin coated RBC (E-Tg) in vitro. Monocytes binding E-Tg were increased significantly in 7 patients out of 14. Percentage of monocytes binding E-Tg were from 1.2 to 4.6% in Hashimoto's patients and 0-0.4% in 7 normal controls. Such specific antigen binding capacity of monocytes in Hashimoto's disease was thought to be due to the presence of cytophilic antibodies on the surface of monocytes. Monocyte cytophilic anti-thyroglobulin antibodies were detected in 24 sera out of 30 patients with Hashimoto's disease. Monocytes from normal healthy donors obtained the ability to form rosette with E-Tg on incubating them with heat-inactivated Hashimoto's sera for 60 min at 4℃. After thorough washing, such monocytes formed rosette with E-Tg in vitro. The rosette formation was immunologically specific and did not form rosette with erythrocytes coated with unrelated antigens such as human serum albumin. The rosette formation was inhibited by the addition of small amount of free thyroglobulin in the medium. Cytophilic activities of sera (% rosette) were correlated with anti-thyroglobulin antibody titers by passive hemagglutination. It was suggested that the monocytes arming with such cytophilic antibodies in vivo might be responsible for specific antigen binding capacity of monocytes in patients with Hashimoto's disease and such armed monocytes may infiltrate in the thyroid gland showing specific affinity to colloidal antigens. Penetration of such cells into the colloid follicles through acinar cells might disrupt the follicular architecture and might play a part of thyroid tissue damage. en-copyright= kn-copyright= en-aut-name=TakehisaYoshiaki en-aut-sei=Takehisa en-aut-mei=Yoshiaki kn-aut-name=竹久義明 kn-aut-sei=竹久 kn-aut-mei=義明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学第三内科学教室 END start-ver=1.4 cd-journal=joma no-vol=89 cd-vols= no-issue=7-8 article-no= start-page=859 end-page=863 dt-received= dt-revised= dt-accepted= dt-pub-year=1977 dt-pub=19770830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the lipid of rat dental pulp II. Lipid peroxidation of rat incisor pulp kn-title=歯髄の脂質に関する研究 II ラット切歯歯髄の脂質過酸化反応 en-subtitle= kn-subtitle= en-abstract=Lipid peroxidation of dental pulp homogenate isolated from rat incisors was induced by ferrous ion. Lipd peroxidation of dental pulp homogenate isolated from rat 3 days after wholebody irradiation at 1000R x-ray was also induced by ferrous ion, and the activity was higher than that of control homogenate. In the extracted lipid components of dental pulps, the peroxidation of phospholipid were marked, but those of choresterol, choresterol ester, mono-,di-, tri-glycerides, and fatty acid (non-esterified) were slightly or negligible. In the phospholipid components, the peroxidation was highly observed in lecithin, phosphatidyl ethanolamine and phosphatidyl serine, and the peroxidation of phosphatidyl ethanolamine showed the most value in them. By the analysis of the fatty acid composition, arachidonic acid was included in the phos-pholipid but not in the triglyceride, suggesting arachidonic acid is substrate of the peroxidation of dental pulps. kn-abstract=1) ラット切歯歯髄のホモゲネートにおいてFe(++)誘導脂質過酸化反応活性が認められた.エックス線全身照射(1000R)したラットより分離した歯髄ホモゲネートのFe(++)誘導脂質過酸化反応は非照射のそれに比して促進がみられた. 2) ラット切歯歯髄脂質の構成脂質中で,過酸化反応を誘起し易い脂質はリン脂質で,中性脂質ではほとんど誘起されなかった. 3) リン脂質中,そのリン脂質構成の大部分をしめるボスファチジルコリン,ホスファチジルエタノールアミン,ホスファチジルセリンにおいて過酸化反応が誘起し得た.中でもホスファチジルエタノールアミンの脂質重量当りの比活性が最も高い値を示した. 4) リン脂質の脂肪酸組成では,アラキドン酸をはじめ,不飽和含量が多く,トリグリセリドではアラキドン酸はみられなかった. en-copyright= kn-copyright= en-aut-name=HashimotoGonosuke en-aut-sei=Hashimoto en-aut-mei=Gonosuke kn-aut-name=橋本郷之助 kn-aut-sei=橋本 kn-aut-mei=郷之助 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=89 cd-vols= no-issue=7-8 article-no= start-page=851 end-page=858 dt-received= dt-revised= dt-accepted= dt-pub-year=1977 dt-pub=19770830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the lipid of rat dental pulp I. Analyses of lipid component and fatty acid composition in rat incisor pulps before and after whole-body x-ray irradiation kn-title=歯髄の脂質に関する研究 I ラット切歯歯髄の脂質ならびに脂肪酸組成の解析と放射線全身照射による変動 en-subtitle= kn-subtitle= en-abstract=Lipids and fatty acids extracted from rat incisor pulps before and after whole-body x-ray irradiation at 1000R were qualitatively and quantitatively analysed by means of thin-layer and gas-liquid chromatography, and the results are as follows. 1) Ratio of the total lipid weight to protein weight was obtained 0.26 in normal rat dental pulps. The ratio in the irradiated group (3 days after irradiation) did not change. 2) In fatty acid composition of lipid of normal rat incisor pulps, palmitic, oleic, stearic, arachidonic, and linoleic acids were much in this order, and palmitic, stearic and oleic acids were major component accounted for over 78% of the total fatty acids. In that of the irradiated group, the decrease of oleic acid and the increase of arachidonic acid were observed comparing those of normal pulp lipid. 3) The major lipid of normal dental pulps composed of phospholipid, choresterol, triglyceride and choresterol ester, and phospholipid and choresterol accounted for about 45% and 30% of the total lipids, respectively. In the irradiated group, the decrease of choresterol and the increase of choresterol ester were represented. 4) In results of tentative identification by various color reaction on the thin-layer chromatograph, the major phospholipids of dental pulps were lecithin, phosphatidyl ethanolamine and phosphatidyl serine, which accounted for over 90% of the total phospholipids. It is significant that phosphatidyl serine in dental pulp is greater than in any other mammalian soft tissue so far studied. In the irradiated group, it was slightly observed the increment of lecithin and the decrement of phosphatidyl serine, but they are not predominant. kn-abstract=ラット切歯歯髄の脂質組成ならびに脂肪酸組成を解析するとともに,あわせてエックス線全身照射の各々の組成に及ぼす影響を研究し次の如き結果を得た.(1)切歯歯髄の総脂質含量は蛋白量相対比にして0.26の値を得た.エックス線全身照射群(1000R照射後3日目のもの)の歯髄も同様0.26の値を得,その差は得られなかった.(2)正常切歯歯髄の総脂質の脂肪酸組成において,パルミチン酸,オイレン酸,ステアリン酸,アラキドン酸,リノール酸の順に主成分として認められ,前三脂肪酸で78%以上を占めた.エックス線全身照射群においてはオレイン酸の減少,アラキドン酸の増加が認められた.口腔領域への部分照射(1000R)でも同様の傾向がみられた.(3)正常切歯歯髄の脂質構成としてリン脂質,コレステロール,トリグリセリド,コレステロールエステルが主成分として認められ,リン脂質は45 % ,コレステロールは30 % を占めた.エックス線全身照射群ではリン脂質,トリグリセリドの構成比に変動はみられなかったが,コレステロールの減少とコレステロールエステルの増加が認められた.(4)正常切歯歯髄リン脂質の構成を各種呈色反応で仮同定した結果,レシチン,ホスファチジルエタノールアミン,ホスファチジルセリンが主成分として90 % 以上を占めた.特にホスファチジルセリン含量が多いのが注目される.照射群ではレシチンの増加,ホスファチジルセリンの減少など若干の組成比に変動がみられたが,対照との差は有意とは言えなかった. en-copyright= kn-copyright= en-aut-name=HashimotoGonosuke en-aut-sei=Hashimoto en-aut-mei=Gonosuke kn-aut-name=橋本郷之助 kn-aut-sei=橋本 kn-aut-mei=郷之助 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=92 cd-vols= no-issue=9-10 article-no= start-page=1015 end-page=1024 dt-received= dt-revised= dt-accepted= dt-pub-year=1980 dt-pub=19801030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Alteration of mitochondrial functions by lipid peroxidation and inhibition by biscoclaurine alkaloid kn-title=脂質過酸化反応によるミトコンドリァ機能の変化とビスコクラウリン型アルカロイドによる阻害作用 en-subtitle= kn-subtitle= en-abstract= kn-abstract=During investigation of the changes in mitochondrial function accompanying lipid peroxidation, it was found that a biscoclaurine alkaroid protected their functional changes. The results obtained were as follows: 1) Fe(2+) induces lipid peroxidation of isolated mitochondria, resulting in deterioration of oxidative phosphorylation. 2) This deterioration relates to alteration in ion compartmentation of the mitochondrial membrane and an increase in latent ATPase activity. 3) This deterioration by Fe(2+) in ion compartmentation of mitochondrial membrane is strongly protected by a biscoclaurine alkaloid, cepharanthine. 4) Cepharanthine also inhibits the mitochondrial. lipid peroxidation induced by Fe(2+). 5) The protective effect of cepharanthine against deterioration in mitochondrial functions caused by Fe(2+) depends on its inhibitive action on lipid peroxidation as well as on its membrane stabilizing action. 6) Cepharanthine inhibits the lipid peroxidation of soybean lecithine liposomes by (60)Co-irradiation. 7) The action of cepharanthine described above is common to head to head type of biscoclaurin alkaloids which have diether bonds. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=2 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=3 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=4 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=5 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=6 ORCID= en-aut-name=EzoeHiroshi en-aut-sei=Ezoe en-aut-mei=Hiroshi kn-aut-name=江添弘 kn-aut-sei=江添 kn-aut-mei=弘 aut-affil-num=7 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=8 ORCID= en-aut-name=MiyakeMasayoshi en-aut-sei=Miyake en-aut-mei=Masayoshi kn-aut-name=三宅正淑 kn-aut-sei=三宅 kn-aut-mei=正淑 aut-affil-num=9 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=10 ORCID= en-aut-name=WakabayashiHisao en-aut-sei=Wakabayashi en-aut-mei=Hisao kn-aut-name=若林寿生 kn-aut-sei=若林 kn-aut-mei=寿生 aut-affil-num=11 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=12 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=13 ORCID= en-aut-name=ShiraishiNoriyuki en-aut-sei=Shiraishi en-aut-mei=Noriyuki kn-aut-name=白石則之 kn-aut-sei=白石 kn-aut-mei=則之 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=高知医科大学生物学教室 en-keyword=Lipid Peroxidation kn-keyword=Lipid Peroxidation en-keyword=Cepharanthine (Biscoclaurine Alkaloid) kn-keyword=Cepharanthine (Biscoclaurine Alkaloid) en-keyword=Mitochondrial Function kn-keyword=Mitochondrial Function END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=11-12 article-no= start-page=1499 end-page=1505 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19791230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of ulcerative colitis in childhood kn-title=小児潰瘍性大腸炎の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Ulcerative colitis in childhood is a rare disease in Japan. A 10-year-old male child was admitted to Okayama University Hospital with a chief complaint of mucous and bloody diarrhea. He had been treated conservatively in another hospital, but the symptoms had not improved. Barium enema examination revealed, from the sigmoid to the transverse colon, abnormal barium coating, numerous small niches, disappearance of the network pattern, and faint spiculations along the margins. Endoscopy demonstrated slight edema, hyperemia, easy bleeding and some purulent secretion. Biopsy specimens showed infiltration of lymphocytes, plasma cells and eosinophilic leucocytes in the mucosa. We made a diagnosis of ulcerative colitis. The patient responded poorly to Salazopyrin and Penicillin, but improved considerably with corticosteroids. en-copyright= kn-copyright= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=1 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=2 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=4 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=5 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=6 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=7 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=9 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=10 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=11 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=小児潰瘍性大腸炎 kn-keyword=小児潰瘍性大腸炎 en-keyword=粘血性下痢便 kn-keyword=粘血性下痢便 END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=5-6 article-no= start-page=567 end-page=575 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19790630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effect of B.C.G. and Splenectomy on survival prolongation of mice with Ehrlich ascites cancer kn-title=エールリッヒ担癌マウスの延命に及ぼすBCGおよび摘脾の効果 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this report, an effective way of B.C.G. in combination with splenectomy is presented for cancer therapy. Ehrlich ascites cancer was inoculated into the footpads of DDS mice. At the appropriate times of tumor growth, a femur was amputated to remove the primary tumor. After several days, the host was rechallenged with Ehrlich ascites cancer. The challange was considered as metastasis. For the first experiments, mice were injected with B.C.G. into primary inoculated tumor and also splenectomized at the amputation. The combined therapy of B.C.G. injection and splenectomy prolonged survival, whereas neither B.C.G. injection nor splenectomy alone did not. For the next examination, the influence of B.C.G. presensitization with or without splenectomy on survival was examined. It was confirmed that the combined therapy was useful for the prolongation of survival. Furthermore, when Ehrlich ascites cancer was reinoculated with sera obtained from tumor bearing mice, splenectomy effectively prolonged survival. The data suggest that B.C.G. therapy is effective for host survival, especially when splenectomy is also performed. en-copyright= kn-copyright= en-aut-name=HashimotoMasaaki en-aut-sei=Hashimoto en-aut-mei=Masaaki kn-aut-name=橋本雅明 kn-aut-sei=橋本 kn-aut-mei=雅明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=BCG kn-keyword=BCG en-keyword=摘脾 kn-keyword=摘脾 en-keyword=エールリッヒ癌 kn-keyword=エールリッヒ癌 en-keyword=DDSマウス kn-keyword=DDSマウス END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=5-6 article-no= start-page=555 end-page=560 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19790630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of chondrosarcoma of rib origin kn-title=肋骨軟骨肉腫の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 64 year old male was admitted to the Okayama University Medical School Hospital in June 1976. Although the patient had no subjective symptoms, the chest X-ray film revealed a tumor shadow in the left upper lung field. The tumor shadow was 8×9 cm, well demarcated, and homogenous. In 1969, at the time of an episode of pneumonia, the tumor shadow was 3×3 cm. At operation, the tumor was a chondrosarcoma of rib origin. The chest roentgenograms are described in this report. en-copyright= kn-copyright= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=1 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=2 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=4 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=5 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=6 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=7 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=8 ORCID= en-aut-name=UchidaHatsuzo en-aut-sei=Uchida en-aut-mei=Hatsuzo kn-aut-name=内田発三 kn-aut-sei=内田 kn-aut-mei=発三 aut-affil-num=9 ORCID= en-aut-name=ShimizuNobuyoshi en-aut-sei=Shimizu en-aut-mei=Nobuyoshi kn-aut-name=清水信義 kn-aut-sei=清水 kn-aut-mei=信義 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=9 en-affil= kn-affil=岡山大学医学部第II外科 affil-num=10 en-affil= kn-affil=岡山大学医学部第II外科 en-keyword=chondrosarcoma kn-keyword=chondrosarcoma en-keyword=rib kn-keyword=rib END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=3-4 article-no= start-page=525 end-page=531 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19790430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of pulmonary bronchogenic cyst complicated by pulmonary tuberculosis kn-title=診断困難であった肺結核と気管支性肺嚢胞の合併症例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 53 year old male was admitted to the Okayama University Medical School Hospital in June 1975 with a history of chronic cough and sputum. The patient had previously undergone treatment for pulmonary tuberculosis for 18 months at another hospital. Roentgenologic examination showed a lobulated mass and fibrotic density in the left upper lung field. Left upper lobectomy was performed. The histopathologic diagnosis was pulmonary bronchogenic cyst with pulmonary tuberculosis in the same segment. In this report, the roentgenological findings and differential diagnosis of pulmonary bronchogenic cyst are described. en-copyright= kn-copyright= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=1 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=2 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=4 ORCID= en-aut-name=MizukawaKiichiro en-aut-sei=Mizukawa en-aut-mei=Kiichiro kn-aut-name=水川帰一郎 kn-aut-sei=水川 kn-aut-mei=帰一郎 aut-affil-num=5 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=6 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=7 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=8 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=9 ORCID= en-aut-name=ItagakiFumio en-aut-sei=Itagaki en-aut-mei=Fumio kn-aut-name=板垣文夫 kn-aut-sei=板垣 kn-aut-mei=文夫 aut-affil-num=10 ORCID= en-aut-name=SimizuNobuyoshi en-aut-sei=Simizu en-aut-mei=Nobuyoshi kn-aut-name=清水信義 kn-aut-sei=清水 kn-aut-mei=信義 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=10 en-affil= kn-affil=岡山大学医学部第II外科 affil-num=11 en-affil= kn-affil=岡山大学医学部第II外科 en-keyword=Bronchogenic cyst kn-keyword=Bronchogenic cyst en-keyword=Pulmonary tuberculosis kn-keyword=Pulmonary tuberculosis END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=3-4 article-no= start-page=359 end-page=368 dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19820430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on ferrous ion-induced lipid peroxidation Part Ⅱ Analysis of the induction period (lag) of ferrous ion-induced lipid peroxidation kn-title=二価鉄誘導脂質過酸化反応に関する研究 第二編 二価鉄誘導脂質過酸化反応における誘導期(lag)の二価鉄の消長による解析 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The author measured simultaneously Fe(Ⅱ)-induced peroxidation of lipid extracted from rat liver mitochondria by the TBA method and the concentration of Fe(Ⅱ) added to the medium quantitatively using Nitoroso-PSAP reagent. 1) An induction period (lag) at the early phase of the reaction of Fe(Ⅱ)-induced lipid peroxidation was observed as well as in mitochondria. 2) After most of the Fe(Ⅱ) concentration had decreased, the TBA-value, after lagtime, increased sharply. 3) Phosphate added to the medium shortened the lag-time. The lag-time in the presence of phosphate varied with the concentration and pH. However, in each case, there was a correlation between the decrement of Fe(Ⅱ) concentration and the length of lag time as described above. 4) By adding EDTA for various reaction times, Fe was chelated immediately, then the TBA value did not increase. 5) The results suggest: iron interacted with the chain reaction of lipid peroxidation, mainly as Fe(Ⅱ) and/or partially Fe(Ⅲ); Fe(Ⅱ) maintains the lag as a inhibitory action to the resolution into malondialdehyde(MDA) from lipid peroxide; Fe(Ⅲ) was required for the formation of MDA. 6) Using these results, the author discussed the mechanisms of Fe(Ⅱ)-induced lipid peroxidation. en-copyright= kn-copyright= en-aut-name=HashimotoKeizi en-aut-sei=Hashimoto en-aut-mei=Keizi kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=ミトコンドリア脂質 kn-keyword=ミトコンドリア脂質 en-keyword=脂質過酸化反応 kn-keyword=脂質過酸化反応 en-keyword=鉄 kn-keyword=鉄 END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=3-4 article-no= start-page=349 end-page=357 dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19820430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on ferrous ion-induced lipid peroxidation Part IQuantitative analysis of ferrous ion in a system of ferrous ion-induced lipid peroxidation kn-title=二価鉄誘導脂質過酸化反応に関する研究 第一編 二価鉄誘導脂質過酸化反応溶液中の二価鉄の定量 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The 2-nitroso-(N-propyl-N-sulfopropylamino)phenol(Nitroso-PSAP), one of the watersoluble derivatives of nitrosoaminophenol, is a very sensitive reagent for the spectrophotometric determination of Fe(Ⅱ). Using Nitroso-PSAP reagent, the author investigated the conditions for determining Fe(Ⅱ) quantitatively and selectively the system of Fe(Ⅱ)-induced lipid peroxidation, and obtained the following results. 1) Fe(Ⅱ) could be measured quantitatively without reductant. The Fe(Ⅱ) complex had a molar absorptivity of 4.5×10(4)dm(3) mol(-1) cm(-1) at 756 nm. 2) Fe(Ⅱ) could be measured quantitatively in the TCA solution removed from the reaction medium for lipid peroxidation. The Fe(Ⅱ) complex had a molar absorptivity of 3.14×10(4)dm(3) mol(-1) at 756nm. 3) Fe(Ⅱ) could be measured quantitatively and selectivily under conditions involving a mixture of Fe(Ⅱ). en-copyright= kn-copyright= en-aut-name=HashimotoKeizi en-aut-sei=Hashimoto en-aut-mei=Keizi kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=鉄定量 kn-keyword=鉄定量 en-keyword=脂質過酸化反応 kn-keyword=脂質過酸化反応 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20090325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=鉄酸化細菌由来の酸化鉄に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HashimotoHideki en-aut-sei=Hashimoto en-aut-mei=Hideki kn-aut-name=橋本英樹 kn-aut-sei=橋本 kn-aut-mei=英樹 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue=7-8 article-no= start-page=701 end-page=708 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19810830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Multiple polypoid filling defects of the duodenal bulb kn-title=十二指腸球部多発陰影欠損について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Multiple polypoid filling defects of the duodenal bulb are infrequently encountered. Two cases of multiple filling defects of the duodenal bulb are reported in this paper. Case 1. A 42 year old female complained of abdominal fullness and epigastralgia. On examination, generalized peripheral lymphadenopathy and marked hepatosplenomegaly were noted. Cervical lymphnode biopsy revealed a diffuse, poorly-differanciated lymphocytic lymphoma. X-ray examination of the gastrointestinal tract showed multiple filling defects localized at the duodenal bulb. Endoscopy disclosed multiple well-defined protrusions with small mucosal ulceration over the the whole circumference of the duodenal wall. Case 2. A 36 year old female had no subjective symptoms. At gastric mass screening, numerous polypoid elevations of the duodenal bulb were pointed out. Detailed gastrointestinal x-ray examination showed numerous, tiny, round polypoid nodules localized at the duodenal bulb. These nodules were 2-3mm in size with no mucosal ulceration. The endoscopic biopsy specimen revealed lymphoid hyperplasia of the duodenal bulb. en-copyright= kn-copyright= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=1 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=2 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=3 ORCID= en-aut-name=MiyakeMasayoshi en-aut-sei=Miyake en-aut-mei=Masayoshi kn-aut-name=三宅正淑 kn-aut-sei=三宅 kn-aut-mei=正淑 aut-affil-num=4 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=5 ORCID= en-aut-name=EzoeHiroshi en-aut-sei=Ezoe en-aut-mei=Hiroshi kn-aut-name=江添弘 kn-aut-sei=江添 kn-aut-mei=弘 aut-affil-num=6 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=7 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=8 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=9 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=10 ORCID= en-aut-name=HayashiKyoichi en-aut-sei=Hayashi en-aut-mei=Kyoichi kn-aut-name=林恭一 kn-aut-sei=林 kn-aut-mei=恭一 aut-affil-num=11 ORCID= en-aut-name=TakaokaKazuko en-aut-sei=Takaoka en-aut-mei=Kazuko kn-aut-name=高岡和子 kn-aut-sei=高岡 kn-aut-mei=和子 aut-affil-num=12 ORCID= en-aut-name=OshimaYukiko en-aut-sei=Oshima en-aut-mei=Yukiko kn-aut-name=大島由起子 kn-aut-sei=大島 kn-aut-mei=由起子 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部第II内科学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部第II内科学教室 affil-num=13 en-affil= kn-affil=三菱水島病院内科 en-keyword=Duodenal bulb kn-keyword=Duodenal bulb en-keyword=multiple polypoid nodules kn-keyword=multiple polypoid nodules END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=11-12 article-no= start-page=1175 end-page=1182 dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19841230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Moving Strip Technique of Electoron Beam Therapy kn-title=電子線moving strip法の試み en-subtitle= kn-subtitle= en-abstract= kn-abstract=The fieldsize in electron beam therapy is determined by the cone size. In cases of skin metastasis of a malignant tumor and so on, which need a large field size and whose area is much larger than the size of the cone, a large field size is usually produced by dividing the portals. However, the dose distribution at the border of the field becomes unequal, and hot and cold dose areas are produced according to the distance between portals. We tried the strip field technique in a large field along the long axis of the body in order to flatten the dose of the border employing the moving strip used for whole abdominal irradiation in ovarian cancer. We set the film in Mix-DP and used the strip field technique with 2.5cm steps. We discussed the relationship between the interval (distance between portals) and the flattening of the dose within the field. Skin movement due to breathing and influences on the flattening of the dose were considered. The proper flatness was obtained at depths of 0,1,2, and 3cm by setting the interval at 0.5cm. When skin movement was produced by breathing in ±1.5mm, the proper flaness was obtained also at a 0.5-cm interval. It seems that smoothing is increased by breathing. An "electron beam moving strip" with a 2.5-cm step and 0.5-cm interval was clinically effective in the treatment of patients with skin metastasis of colon cancer. en-copyright= kn-copyright= en-aut-name=MatsushimaKisho en-aut-sei=Matsushima en-aut-mei=Kisho kn-aut-name=松島紀志夫 kn-aut-sei=松島 kn-aut-mei=紀志夫 aut-affil-num=1 ORCID= en-aut-name=WakasaHiroyuki en-aut-sei=Wakasa en-aut-mei=Hiroyuki kn-aut-name=若狭弘之 kn-aut-sei=若狭 kn-aut-mei=弘之 aut-affil-num=2 ORCID= en-aut-name=OguriNobuhiro en-aut-sei=Oguri en-aut-mei=Nobuhiro kn-aut-name=小栗宣博 kn-aut-sei=小栗 kn-aut-mei=宣博 aut-affil-num=3 ORCID= en-aut-name=KitayamaTakuichi en-aut-sei=Kitayama en-aut-mei=Takuichi kn-aut-name=北山卓一 kn-aut-sei=北山 kn-aut-mei=卓一 aut-affil-num=4 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=5 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=三上泰隆 kn-aut-sei=三上 kn-aut-mei=泰隆 aut-affil-num=6 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=7 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=8 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=電子線治療技術 kn-keyword=電子線治療技術 en-keyword=moving strip 法 kn-keyword=moving strip 法 en-keyword=皮膚転移腫 kn-keyword=皮膚転移腫 END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=11-12 article-no= start-page=1063 end-page=1071 dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19841230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An Evaluation of the Pendulum Technique of Electron Beam Therapy kn-title=電子線振子照射法の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Electron beam therapy of lesions such as cutaneous metastatic carcinoma and reticulum cell sarcoma is performed via multiple portals for a wide irradiation field. However, the dose distribution in border areas is generally uneven, resulting in hot and cold dose areas depending on the intervals of the portals. We performed electron irradiation by the pendulum technique, especially on curved areas, and evaluated the technique in various respects. Pendulum electron beam irradiation is indicated when the length of the cone must be reduced in order to deliver the target volume near the skin surface as well as to avoid the occurrence of hot spots deep in the body. We prepared a 15cm rotating cone by cutting a 30cm fixed irradiation cone. The modification posed no disadvantages in terms of extent and flatness of the beam, or stability during rotation. After determining the relationship between the rotation speed and the dose, the technique was successfully applied to a patient with adult T-cell lymphoma, at a total of 3000cGy. en-copyright= kn-copyright= en-aut-name=MatsushimaKishio en-aut-sei=Matsushima en-aut-mei=Kishio kn-aut-name=松島紀志夫 kn-aut-sei=松島 kn-aut-mei=紀志夫 aut-affil-num=1 ORCID= en-aut-name=OguriNobuhiro en-aut-sei=Oguri en-aut-mei=Nobuhiro kn-aut-name=小栗宣博 kn-aut-sei=小栗 kn-aut-mei=宣博 aut-affil-num=2 ORCID= en-aut-name=WakasaHiroyuki en-aut-sei=Wakasa en-aut-mei=Hiroyuki kn-aut-name=若狭弘之 kn-aut-sei=若狭 kn-aut-mei=弘之 aut-affil-num=3 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=4 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=三上泰隆 kn-aut-sei=三上 kn-aut-mei=泰隆 aut-affil-num=5 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=6 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=7 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=8 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=9 ORCID= en-aut-name=FujimotoWataru en-aut-sei=Fujimoto en-aut-mei=Wataru kn-aut-name=藤本亘 kn-aut-sei=藤本 kn-aut-mei=亘 aut-affil-num=10 ORCID= en-aut-name=KodamaHajime en-aut-sei=Kodama en-aut-mei=Hajime kn-aut-name=小玉肇 kn-aut-sei=小玉 kn-aut-mei=肇 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部皮膚科学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部皮膚科学教室 en-keyword=放射線治療技術 kn-keyword=放射線治療技術 en-keyword=電子線振子照射法 kn-keyword=電子線振子照射法 en-keyword=ATL kn-keyword=ATL END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=11-12 article-no= start-page=1053 end-page=1061 dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19841230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Comparison of CT image of basal ganglia calcification with clinical symptoms kn-title=大脳基底核石灰化CT像と臨床症状との対比 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We investigated the relationship between the frequency of basal ganglia calcification appearing in CT scans and clinical symptoms in 3,599 patients. Basal ganglia were calcified in eleven patients (0.3%), of whom seven had calcification of the bilateral G. Pallidus, but no clinical symptoms. A relationship between calcification and clinical symptoms was shown in two patients under ten years old, a three-year-old with young brain atrophy and a six-year-old with a gonadotropin-producing brain tumor. Especially in patients over forty years old, a direct relationship between G.P. calcification and clinical symptoms was not shown, and calcification was considered to be pyhsilogical. en-copyright= kn-copyright= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=1 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=2 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=3 ORCID= en-aut-name=NiiyaHarutaka en-aut-sei=Niiya en-aut-mei=Harutaka kn-aut-name=新屋晴孝 kn-aut-sei=新屋 kn-aut-mei=晴孝 aut-affil-num=4 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=5 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=6 ORCID= en-aut-name=KoyamaNaoki en-aut-sei=Koyama en-aut-mei=Naoki kn-aut-name=小山直樹 kn-aut-sei=小山 kn-aut-mei=直樹 aut-affil-num=7 ORCID= en-aut-name=HinoHiroyuki en-aut-sei=Hino en-aut-mei=Hiroyuki kn-aut-name=日野裕之 kn-aut-sei=日野 kn-aut-mei=裕之 aut-affil-num=8 ORCID= en-aut-name=YamamotoHiromichi en-aut-sei=Yamamoto en-aut-mei=Hiromichi kn-aut-name=山本博道 kn-aut-sei=山本 kn-aut-mei=博道 aut-affil-num=9 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=10 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=11 ORCID= en-aut-name=MatsushimaKishio en-aut-sei=Matsushima en-aut-mei=Kishio kn-aut-name=松島紀志夫 kn-aut-sei=松島 kn-aut-mei=紀志夫 aut-affil-num=12 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=13 ORCID= en-aut-name=IrisawaMinoru en-aut-sei=Irisawa en-aut-mei=Minoru kn-aut-name=入沢実 kn-aut-sei=入沢 kn-aut-mei=実 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部付属病院中央放射線部 affil-num=13 en-affil= kn-affil=香川県立中央病院放射線科 affil-num=14 en-affil= kn-affil=近畿大学医学部放射線医学教室 en-keyword=head CT kn-keyword=head CT en-keyword=cerebral calcification kn-keyword=cerebral calcification en-keyword=basal ganglia kn-keyword=basal ganglia END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue=1-2 article-no= start-page=63 end-page=78 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19810228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study of CT-diagnosis for pancreatic diseases kn-title=膵疾患におけるCT診断 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The diagnosis of pancreatic diseases is difficult and examination techniques such as hypo tonic duodenography, ERSP, and PTC have been used to facilitate this. Computerized tomography (CT) has recently been introduced for the diagnosis of abdominal organs, and grea hopes were held for its application in pancreatic disease. However, according to reports bases on numerous clinical experiments, it is concluded that its value is not so high as expected Therefore, under present conditions, we are obliged to depend on other diagnostic technique which require great skill and cause pain to patients. This report deals with investigation o the image in cases we have experienced. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=2 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=3 ORCID= en-aut-name=WakabayashiHisao en-aut-sei=Wakabayashi en-aut-mei=Hisao kn-aut-name=若林寿生 kn-aut-sei=若林 kn-aut-mei=寿生 aut-affil-num=4 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=5 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=6 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=7 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=8 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本眞 kn-aut-sei=木本 kn-aut-mei=眞 aut-affil-num=9 ORCID= en-aut-name=EzoeHiroshi en-aut-sei=Ezoe en-aut-mei=Hiroshi kn-aut-name=江添弘 kn-aut-sei=江添 kn-aut-mei=弘 aut-affil-num=10 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=11 ORCID= en-aut-name=MiyakeMasayoshi en-aut-sei=Miyake en-aut-mei=Masayoshi kn-aut-name=三宅正淑 kn-aut-sei=三宅 kn-aut-mei=正淑 aut-affil-num=12 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=computed tomography kn-keyword=computed tomography en-keyword=Pancreas kn-keyword=Pancreas END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue=7-8 article-no= start-page=687 end-page=695 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19860830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Radiation Therapy of Angioblastoma (Nakagawa) of the Skin kn-title=血管芽細胞腫(中川)の放射線治療 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Percent depth dose curves of Lineac electron beam and Dermopan soft X-ray, which are used for radiation therapy of surface tumors, were studied in 2 patients with angioblastoma (Nakagawa) who had been followed up for a long time after radiation therapy. The results are discussed with a review of the literature. Lineac electron beam therapy at low doses that do not cause remote complications appeared to be useful in the treatment of surface tumors selected after careful consideration of the indications. en-copyright= kn-copyright= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=1 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=2 ORCID= en-aut-name=SatohNobuo en-aut-sei=Satoh en-aut-mei=Nobuo kn-aut-name=佐藤伸夫 kn-aut-sei=佐藤 kn-aut-mei=伸夫 aut-affil-num=3 ORCID= en-aut-name=YamamotoYoshio en-aut-sei=Yamamoto en-aut-mei=Yoshio kn-aut-name=山本淑雄 kn-aut-sei=山本 kn-aut-mei=淑雄 aut-affil-num=4 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=5 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=6 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=7 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=8 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=9 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=10 ORCID= en-aut-name=ArakawaKenzo en-aut-sei=Arakawa en-aut-mei=Kenzo kn-aut-name=荒川謙三 kn-aut-sei=荒川 kn-aut-mei=謙三 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=11 en-affil= kn-affil=岡山大学医学部皮膚科学教室 en-keyword=血管芽細胞腫(中川) kn-keyword=血管芽細胞腫(中川) en-keyword=放射線治療 kn-keyword=放射線治療 en-keyword=電子線治療 kn-keyword=電子線治療 en-keyword=Dermopan 軟 X線治療 kn-keyword=Dermopan 軟 X線治療 END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=9-10 article-no= start-page=823 end-page=831 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19851030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical evaluation of serum ferritin levels in primary lung cancer patients with radiation therapy Comparing with serum CEA levels kn-title=放射線治療を施行した原発性肺癌患者における血清フェリチン値の臨床的評価 ―血清CEA値と比較して― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Serum ferritin and serum carcinogenic embryonic antigen (CEA) levels in 153 patients (male: 112, female: 41) with primary lung cancer were simultaneously measured and compared with the histological type, clinical stage and clinical course. No correlation between serum ferritin and CEA levels was found. A higher percentage of positive test results for both serum ferritin and CEA was associated with advanced stages and metastasis in other organs. From the point of view of histological classification, high ferritin levels were mainly found in the patients with small-cell types of cancer. In contrast, high CEA levels were found in patients with adenocarcinoma. Therefore, the measurement of serum ferritin was not efficient as a screening test for lung cancer. Serum ferritin levels were, however, correlated with the efficacy of therapy and the clinical course. en-copyright= kn-copyright= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=3 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=4 ORCID= en-aut-name=UedaHiroyuki en-aut-sei=Ueda en-aut-mei=Hiroyuki kn-aut-name=上田裕之 kn-aut-sei=上田 kn-aut-mei=裕之 aut-affil-num=5 ORCID= en-aut-name=SatohNobuo en-aut-sei=Satoh en-aut-mei=Nobuo kn-aut-name=佐藤伸夫 kn-aut-sei=佐藤 kn-aut-mei=伸夫 aut-affil-num=6 ORCID= en-aut-name=NakamuraTetsuya en-aut-sei=Nakamura en-aut-mei=Tetsuya kn-aut-name=中村哲也 kn-aut-sei=中村 kn-aut-mei=哲也 aut-affil-num=7 ORCID= en-aut-name=YamamotoHiromichi en-aut-sei=Yamamoto en-aut-mei=Hiromichi kn-aut-name=山本博道 kn-aut-sei=山本 kn-aut-mei=博道 aut-affil-num=8 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=9 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=10 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=11 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=12 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=国立療養所山陽荘病院放射線科 en-keyword=原発性肺癌 kn-keyword=原発性肺癌 en-keyword=血清フェリチン値 kn-keyword=血清フェリチン値 en-keyword=血清CEA値 kn-keyword=血清CEA値 END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue=3-4 article-no= start-page=323 end-page=330 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19860430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Calcification of vertebral arteries of comparison of CT findings and clinical symptoms kn-title=椎骨動脈の石灰化 CT像と臨床症状との対比 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We analyzed calcifications in 557 computed tomography films of the head. Adnormal findings of calcification of vertebral arteroes were obrained in 36 of the 577 cases. In the 36 cases, vertigo was observed in 24 cases (66.7%), and brain atrophy in 10 cases (27.2%). The calcification of vertebral arteries (arteriosclerosis) correlated significantly with vertigo. Patients with vertigo should be examined by computed tomography for calcification of vertebral arteries at the level of the foramen magnum. en-copyright= kn-copyright= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=1 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=2 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=3 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=4 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=5 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=6 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=7 ORCID= en-aut-name=NiiyaHarutaka en-aut-sei=Niiya en-aut-mei=Harutaka kn-aut-name=新屋晴孝 kn-aut-sei=新屋 kn-aut-mei=晴孝 aut-affil-num=8 ORCID= en-aut-name=UedaHiroyuki en-aut-sei=Ueda en-aut-mei=Hiroyuki kn-aut-name=上田裕之 kn-aut-sei=上田 kn-aut-mei=裕之 aut-affil-num=9 ORCID= en-aut-name=ShimizuMitsuharu en-aut-sei=Shimizu en-aut-mei=Mitsuharu kn-aut-name=清水光春 kn-aut-sei=清水 kn-aut-mei=光春 aut-affil-num=10 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=11 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=12 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=13 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=国立療養所山陽荘病院 en-keyword=head CT kn-keyword=head CT en-keyword=extrapyramidal symptoms kn-keyword=extrapyramidal symptoms en-keyword=vertebral arterial calcification kn-keyword=vertebral arterial calcification END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=5-6 article-no= start-page=475 end-page=480 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19850630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of left inferior vena cave kn-title=左側下大静脈の一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We found a case of left-sided inferior vena cava(ivc) by chance upon upper abdominal CT examination. Left-sided ivc rarely presents clinical symptoms, but it is necessary to distinguish ivc from abnormal masses such as retroperitoneal tumors or lymphnodal swelling. We discussed left-sided ivc and the literature about it. en-copyright= kn-copyright= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=1 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=2 ORCID= en-aut-name=JoujaIkuo en-aut-sei=Jouja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=3 ORCID= en-aut-name=YamamotoYoshio en-aut-sei=Yamamoto en-aut-mei=Yoshio kn-aut-name=山本淑雄 kn-aut-sei=山本 kn-aut-mei=淑雄 aut-affil-num=4 ORCID= en-aut-name=UedaHiroyuki en-aut-sei=Ueda en-aut-mei=Hiroyuki kn-aut-name=上田裕之 kn-aut-sei=上田 kn-aut-mei=裕之 aut-affil-num=5 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=6 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=7 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=8 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=9 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=香川県立中央病院放射線科 en-keyword=左側下大静脈 kn-keyword=左側下大静脈 en-keyword=腹部CT kn-keyword=腹部CT END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue=1-2 article-no= start-page=41 end-page=48 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19860228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Magnetic resonance imaging in aortic aneurysm kn-title=大動脈瘤のMRI en-subtitle= kn-subtitle= en-abstract= kn-abstract=At Okayama University Medical School, the clinical application of magnetic resonance imaging (MRI) started in August 1984, and 16 patients with aortic aneurysm have been imaged by short spin echo (TR400msec, TE40msec) with a Toshiba MRT-15A (resistive type of magnet with a strength of 0.15T).MRI demonstrated the intimal flap and enabled the differentiatian between true and false lumens from the signal intensity. Thrombi were shown with high intensity and were differentiated from fast blood flow, but in some cases clots could not be distinguished from slow flow.MRI in which multiple planes are imaged directly without contrast medium, is a very useful imaging modality for the evaluation of aortic aneurysm. en-copyright= kn-copyright= en-aut-name=KajiMitumasa en-aut-sei=Kaji en-aut-mei=Mitumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=1 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=2 ORCID= en-aut-name=ShimizuMituharu en-aut-sei=Shimizu en-aut-mei=Mituharu kn-aut-name=清水光春 kn-aut-sei=清水 kn-aut-mei=光春 aut-affil-num=3 ORCID= en-aut-name=NakamuraTetsuya en-aut-sei=Nakamura en-aut-mei=Tetsuya kn-aut-name=中村哲也 kn-aut-sei=中村 kn-aut-mei=哲也 aut-affil-num=4 ORCID= en-aut-name=UedaHiroyuki en-aut-sei=Ueda en-aut-mei=Hiroyuki kn-aut-name=上田裕之 kn-aut-sei=上田 kn-aut-mei=裕之 aut-affil-num=5 ORCID= en-aut-name=YamamotoYoshio en-aut-sei=Yamamoto en-aut-mei=Yoshio kn-aut-name=山本淑雄 kn-aut-sei=山本 kn-aut-mei=淑雄 aut-affil-num=6 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=7 ORCID= en-aut-name=KomotoShin en-aut-sei=Komoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=8 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=9 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=10 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=11 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=12 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=13 ORCID= en-aut-name=UtidaHatsuzou en-aut-sei=Utida en-aut-mei=Hatsuzou kn-aut-name=内田發三 kn-aut-sei=内田 kn-aut-mei=發三 aut-affil-num=14 ORCID= en-aut-name=TeramotoShigeru en-aut-sei=Teramoto en-aut-mei=Shigeru kn-aut-name=寺本滋 kn-aut-sei=寺本 kn-aut-mei=滋 aut-affil-num=15 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=岡山大学医学部第二外科学教室 affil-num=15 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=MRI Magnetic Resonance Imaging(核磁気共鳴画像） kn-keyword=MRI Magnetic Resonance Imaging(核磁気共鳴画像） en-keyword=大動脈瘤 kn-keyword=大動脈瘤 END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=1-2 article-no= start-page=101 end-page=112 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19850225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Early clinical experience with NMR-CT kn-title=NMR-CTの初期臨床経験 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We have used an NMR-CT scanner clinically since August 1 1984. We report herein the operating pulse sepuences, and present 5 cases of 226 cases that we have examined. From our clinical experience during the past four months, we describe the advantages and disadvantages of NMR-CT. The advantages are that: 1) it is possible to recognize blood vessels without contrast materials and to evaluate the blood flow 2) there are neither bone nor air artifacts, and 3) it is possible to get the tomogram in any direction. The disadvantages are that: 1) the examination time is very long, 2) there are artifacts from ferromagnetic substances placed in the body, 3) when palse sequence is changed, images are different from each other, and 4) because of respiratory motion artifacts, the images of the chest and abdomen are inferior to those of other parts of the body. en-copyright= kn-copyright= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=1 ORCID= en-aut-name=SatoNobuo en-aut-sei=Sato en-aut-mei=Nobuo kn-aut-name=佐藤伸夫 kn-aut-sei=佐藤 kn-aut-mei=伸夫 aut-affil-num=2 ORCID= en-aut-name=FujishimaMamoru en-aut-sei=Fujishima en-aut-mei=Mamoru kn-aut-name=藤島護 kn-aut-sei=藤島 kn-aut-mei=護 aut-affil-num=3 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=4 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=5 ORCID= en-aut-name=NiiyaHarutaka en-aut-sei=Niiya en-aut-mei=Harutaka kn-aut-name=新屋晴孝 kn-aut-sei=新屋 kn-aut-mei=晴孝 aut-affil-num=6 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=7 ORCID= en-aut-name=YamamotoHiromichi en-aut-sei=Yamamoto en-aut-mei=Hiromichi kn-aut-name=山本博道 kn-aut-sei=山本 kn-aut-mei=博道 aut-affil-num=8 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=9 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=10 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=11 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=12 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=13 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=14 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=15 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=15 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=nucler magnetic resonance kn-keyword=nucler magnetic resonance en-keyword=spin echo kn-keyword=spin echo en-keyword=inversion recovery kn-keyword=inversion recovery en-keyword=T(1) relaxation time kn-keyword=T(1) relaxation time en-keyword=T(2) relaxation time kn-keyword=T(2) relaxation time END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=1-2 article-no= start-page=91 end-page=99 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19850225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Difficulty in determining the extent of metastatic lesions in bone scintigrams: A case report. kn-title=骨転移放射線治療において骨シンチグラムで病巣範囲決定に問題があった2症例の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Radiation therapy for bone metastasis of malignant tumors is useful for reducing pain and is often used. Bone scintigraphy is useful for the early detection of bone metastasis and for staging, and is important in making plans for the irradiation of metastatic bone lesions. However, the images of metastatic bone lesions vary, so the irradiation field must be decided by comparison with plain films, computed tomography, and so on. en-copyright= kn-copyright= en-aut-name=UedaHiroyuki en-aut-sei=Ueda en-aut-mei=Hiroyuki kn-aut-name=上田裕之 kn-aut-sei=上田 kn-aut-mei=裕之 aut-affil-num=1 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=2 ORCID= en-aut-name=JyojaIkuo en-aut-sei=Jyoja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=3 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=4 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=5 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=6 ORCID= en-aut-name=SatoNobuo en-aut-sei=Sato en-aut-mei=Nobuo kn-aut-name=佐藤伸夫 kn-aut-sei=佐藤 kn-aut-mei=伸夫 aut-affil-num=7 ORCID= en-aut-name=NakamuraTetsuya en-aut-sei=Nakamura en-aut-mei=Tetsuya kn-aut-name=中村哲也 kn-aut-sei=中村 kn-aut-mei=哲也 aut-affil-num=8 ORCID= en-aut-name=HinoHiroyuki en-aut-sei=Hino en-aut-mei=Hiroyuki kn-aut-name=日野祐之 kn-aut-sei=日野 kn-aut-mei=祐之 aut-affil-num=9 ORCID= en-aut-name=KoyamaNaoki en-aut-sei=Koyama en-aut-mei=Naoki kn-aut-name=小山直樹 kn-aut-sei=小山 kn-aut-mei=直樹 aut-affil-num=10 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=11 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=bone scintigram kn-keyword=bone scintigram en-keyword=bone metastasis kn-keyword=bone metastasis en-keyword=radiation therapy kn-keyword=radiation therapy en-keyword=bone CT kn-keyword=bone CT END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=1-2 article-no= start-page=55 end-page=63 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19850225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serum ferritin levels in hospital patients kn-title=各種疾患における血清フェリチン値の臨床的評価 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Serum ferritin levels were determined in 75 hematologic, 1205 malignant, and 538 benign diseases. In hematologic diseases the serum ferritin level was generally low in iron deficiency anemia, but high in hemochromatosis, aplastic anemia, and leukemia. In malignant diseases the serum ferritin concentration was increased remarkably in lung, liver, biliary, and urogential diseases and in malignant lymphoma. Among benign diseases hepatitis cases showed a tendency for high serum ferritin levels. Serum ferritin levels are influenced by various factors, and their careful evaluation may be essential for understanding of the underlining disease process. en-copyright= kn-copyright= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=3 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=4 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=5 ORCID= en-aut-name=ShiraishiNoriyuki en-aut-sei=Shiraishi en-aut-mei=Noriyuki kn-aut-name=白石則之 kn-aut-sei=白石 kn-aut-mei=則之 aut-affil-num=6 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=7 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=8 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=9 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=血清フェリチン値 kn-keyword=血清フェリチン値 en-keyword=悪性腫瘍 kn-keyword=悪性腫瘍 en-keyword=radioimmunoassay kn-keyword=radioimmunoassay END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=1-2 article-no= start-page=47 end-page=53 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19850225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the consistency of internally taken contrast medium for Pancreas CT kn-title=腹部CT検査における内服させる造影剤濃度の研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A problem of Pancreatic CT scanning is the discrimination between the pancreas and the adjacent gastrointestinal tract. Generally we administer a dilution of gastrografin internally to make the discrimination. The degree of dilution has been decided by experience at each hospital. When the consistency of the contrast medium is low in density, an enhancement effect cannot be expected, but when the consistency is high, artifacts appear. We have experimented on the degree of the dilution and CT-No to decide the optimum consistency of gastrografin for the diagnosis of pancreatic disease. Statistical analysis of the results show the optimum dilution of gastrografin to be 1.5%. en-copyright= kn-copyright= en-aut-name=MatsushimaKishio en-aut-sei=Matsushima en-aut-mei=Kishio kn-aut-name=松島紀志夫 kn-aut-sei=松島 kn-aut-mei=紀志夫 aut-affil-num=1 ORCID= en-aut-name=MimuraSeiichi en-aut-sei=Mimura en-aut-mei=Seiichi kn-aut-name=三村誠一 kn-aut-sei=三村 kn-aut-mei=誠一 aut-affil-num=2 ORCID= en-aut-name=TaharaSeiji en-aut-sei=Tahara en-aut-mei=Seiji kn-aut-name=田原誠司 kn-aut-sei=田原 kn-aut-mei=誠司 aut-affil-num=3 ORCID= en-aut-name=KitayamaTakuichi en-aut-sei=Kitayama en-aut-mei=Takuichi kn-aut-name=北山卓一 kn-aut-sei=北山 kn-aut-mei=卓一 aut-affil-num=4 ORCID= en-aut-name=InamuraKeiji en-aut-sei=Inamura en-aut-mei=Keiji kn-aut-name=稲村圭司 kn-aut-sei=稲村 kn-aut-mei=圭司 aut-affil-num=5 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=三上泰隆 kn-aut-sei=三上 kn-aut-mei=泰隆 aut-affil-num=6 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本敬二 kn-aut-sei=橋本 kn-aut-mei=敬二 aut-affil-num=7 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=8 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=Pancreas CT kn-keyword=Pancreas CT en-keyword=希釈造影剤濃度 kn-keyword=希釈造影剤濃度 en-keyword=視覚評価の統計処理 kn-keyword=視覚評価の統計処理 END start-ver=1.4 cd-journal=joma no-vol=100 cd-vols= no-issue=9-10 article-no= start-page=951 end-page=957 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=1988 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Results of radiotherapy for lung cancer patients kn-title=岡山大学放射線科入院患者における肺癌の放射線治療成績の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The results of radiotherapy were investigated in 49 patients with lung cancer admitted to the Department of Radiology, Okayama University Hospital. Of the 26 patients not undergoing surgery, the one-year survival rate was 100% in the stage I patients, 55% in the stage Ⅲ patients and 56% in the stage Ⅳ patients, and the two-year survival rate was 50% in the stage I patients, 0% in the stage Ⅲ patients and 9% in the stage Ⅳ patients. A significant difference in survival between patients irradiated with over 60 Gy and patients irradiated with less than 60 Gy was recognized among those not undergoing surgery. However, with respect to the frequency of local recurrence and distant metastases, a correlation with the irradiated dose was not demonstrated. Local recurrence and distant metastases were not observed in 5 of 6 patients who received preventive irradiation after curative surgery was conducted. Concerning 11 patients after non-curative surgery, local recurrence and distant metastases were recognized in 3 of them, and 7 of them showed a favourable outcome brought about by the irradiation after surgery as expected. In 6 patients with local recurrence after surgery, the survival period after radiotherapy was less than 13 months. en-copyright= kn-copyright= en-aut-name=NoriyasuToshiaki en-aut-sei=Noriyasu en-aut-mei=Toshiaki kn-aut-name=則安俊昭 kn-aut-sei=則安 kn-aut-mei=俊昭 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=3 ORCID= en-aut-name=MimuraHidehumi en-aut-sei=Mimura en-aut-mei=Hidehumi kn-aut-name=三村秀文 kn-aut-sei=三村 kn-aut-mei=秀文 aut-affil-num=4 ORCID= en-aut-name=MitaniMasahiko en-aut-sei=Mitani en-aut-mei=Masahiko kn-aut-name=三谷政彦 kn-aut-sei=三谷 kn-aut-mei=政彦 aut-affil-num=5 ORCID= en-aut-name=NagayamaMasako en-aut-sei=Nagayama en-aut-mei=Masako kn-aut-name=永山雅子 kn-aut-sei=永山 kn-aut-mei=雅子 aut-affil-num=6 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=7 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=8 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=9 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=肺癌 kn-keyword=肺癌 en-keyword=放射線治療 kn-keyword=放射線治療 en-keyword=治療成績 kn-keyword=治療成績 END start-ver=1.4 cd-journal=joma no-vol=99 cd-vols= no-issue=7-8 article-no= start-page=1013 end-page=1016 dt-received= dt-revised= dt-accepted= dt-pub-year=1987 dt-pub=19870830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Clinical Study of Bone Metastasis in Carcinoma kn-title=転移性骨腫瘍の臨床症状 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The study included 40 cases of bone metastasis experienced from January 1982 to August 1986 at the Department of Radiology, Okayama University Hospital. The rate of pain Remission was 89.6% in 29 patients given radiotherapy. Increases in serum ALP and LDH were found in a few patients and a quarter of these patients improved after radiotherapy. Serum Ca increased in 5 patients with multiple bone metastases. en-copyright= kn-copyright= en-aut-name=SatohNobuo en-aut-sei=Satoh en-aut-mei=Nobuo kn-aut-name=佐藤伸夫 kn-aut-sei=佐藤 kn-aut-mei=伸夫 aut-affil-num=1 ORCID= en-aut-name=UedaHiroyuki en-aut-sei=Ueda en-aut-mei=Hiroyuki kn-aut-name=上田裕之 kn-aut-sei=上田 kn-aut-mei=裕之 aut-affil-num=2 ORCID= en-aut-name=NakamuraTetsuya en-aut-sei=Nakamura en-aut-mei=Tetsuya kn-aut-name=中村哲也 kn-aut-sei=中村 kn-aut-mei=哲也 aut-affil-num=3 ORCID= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name=黒田昌宏 kn-aut-sei=黒田 kn-aut-mei=昌宏 aut-affil-num=4 ORCID= en-aut-name=KanzakiNoriko en-aut-sei=Kanzaki en-aut-mei=Noriko kn-aut-name=神崎典子 kn-aut-sei=神崎 kn-aut-mei=典子 aut-affil-num=5 ORCID= en-aut-name=MizutaAkihumi en-aut-sei=Mizuta en-aut-mei=Akihumi kn-aut-name=水田昭文 kn-aut-sei=水田 kn-aut-mei=昭文 aut-affil-num=6 ORCID= en-aut-name=MurakamiKiminori en-aut-sei=Murakami en-aut-mei=Kiminori kn-aut-name=村上公則 kn-aut-sei=村上 kn-aut-mei=公則 aut-affil-num=7 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=8 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=9 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=10 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=bone metastasis kn-keyword=bone metastasis en-keyword=clinical symptom kn-keyword=clinical symptom en-keyword=radiotherapy kn-keyword=radiotherapy END start-ver=1.4 cd-journal=joma no-vol=100 cd-vols= no-issue=7-8 article-no= start-page=743 end-page=751 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=1988 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=MRI of meningioma kn-title=髄膜腫のMRI en-subtitle= kn-subtitle= en-abstract= kn-abstract=MRI has gained a prominent position in the diagnosis of brain tumors. We examined 30 cases of meningiomas and distinguished their subtype according to the criteria of Rubinic histology. We discussed the MRI findings and compared then with X-CT findings so to their intensity, delination of tumors, whether accompanied by peripheral edema, and T(1) values. MRI delinated the tumors as well as CE-CT. No remarkable difference was found between the subtypes. en-copyright= kn-copyright= en-aut-name=YamamotoYoshio en-aut-sei=Yamamoto en-aut-mei=Yoshio kn-aut-name=山本淑雄 kn-aut-sei=山本 kn-aut-mei=淑雄 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=KajiMitumasa en-aut-sei=Kaji en-aut-mei=Mitumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=3 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=4 ORCID= en-aut-name=NoriyasuToshiaki en-aut-sei=Noriyasu en-aut-mei=Toshiaki kn-aut-name=則安俊昭 kn-aut-sei=則安 kn-aut-mei=俊昭 aut-affil-num=5 ORCID= en-aut-name=InoueNobuhiro en-aut-sei=Inoue en-aut-mei=Nobuhiro kn-aut-name=井上信浩 kn-aut-sei=井上 kn-aut-mei=信浩 aut-affil-num=6 ORCID= en-aut-name=MitaniMasahiro en-aut-sei=Mitani en-aut-mei=Masahiro kn-aut-name=三谷政彦 kn-aut-sei=三谷 kn-aut-mei=政彦 aut-affil-num=7 ORCID= en-aut-name=FujishimaMamoru en-aut-sei=Fujishima en-aut-mei=Mamoru kn-aut-name=藤島護 kn-aut-sei=藤島 kn-aut-mei=護 aut-affil-num=8 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=9 ORCID= en-aut-name=HashimmotoKeiji en-aut-sei=Hashimmoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=10 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=11 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=MRI kn-keyword=MRI en-keyword=脳腫瘍 kn-keyword=脳腫瘍 en-keyword=髄膜腫(meningioma) kn-keyword=髄膜腫(meningioma) END start-ver=1.4 cd-journal=joma no-vol=100 cd-vols= no-issue=5-6 article-no= start-page=465 end-page=471 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=1988 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of periarteritis nodosa with advanced A-V block and ventricular tachycardia kn-title=高度房室ブロックおよび心室性頻拍を合併した結節性動脈周囲炎の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A case of periarteritis nodosa with advanced A-V block and ventricular tachycardia is reported. The patient was a 62-year-old man who was admitted to Ibara City Hospital because of leg pain and fever. Laboratory examinations and microscopic examination of biopsy sections of the soleus muscle revealed that he had periarteritis nodosa. His electro cardiogram (ECG) and chest X-ray films on admission were normal. Treatment with prednisolone resulted in relief of his complaints, and improved laboratory data. One year later the parient complained of fainting attacks, and an ECG indicated non-sustained ventricular tachycardia. Two months later, a I° A-V block with LBBB appeared, which progressed to complete A-V block within a month. Good results were achieved with ventricular pacing (VVI) in this patient. en-copyright= kn-copyright= en-aut-name=HashimotoNoriaki en-aut-sei=Hashimoto en-aut-mei=Noriaki kn-aut-name=橋本訓招 kn-aut-sei=橋本 kn-aut-mei=訓招 aut-affil-num=1 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斉藤大治 kn-aut-sei=斉藤 kn-aut-mei=大治 aut-affil-num=2 ORCID= en-aut-name=UeedaMasayuki en-aut-sei=Ueeda en-aut-mei=Masayuki kn-aut-name=上枝正幸 kn-aut-sei=上枝 kn-aut-mei=正幸 aut-affil-num=3 ORCID= en-aut-name=TsujiTakao en-aut-sei=Tsuji en-aut-mei=Takao kn-aut-name=辻孝夫 kn-aut-sei=辻 kn-aut-mei=孝夫 aut-affil-num=4 ORCID= en-aut-name=KunishiKensuke en-aut-sei=Kunishi en-aut-mei=Kensuke kn-aut-name=国司研介 kn-aut-sei=国司 kn-aut-mei=研介 aut-affil-num=5 ORCID= en-aut-name=IwanoIkuzo en-aut-sei=Iwano en-aut-mei=Ikuzo kn-aut-name=岩野郁造 kn-aut-sei=岩野 kn-aut-mei=郁造 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=5 en-affil= kn-affil=井原市民病院内科 affil-num=6 en-affil= kn-affil=井原市民病院内科 en-keyword=結節性動脈周囲炎 kn-keyword=結節性動脈周囲炎 en-keyword=心室性頻拍 kn-keyword=心室性頻拍 en-keyword=房室プロック kn-keyword=房室プロック en-keyword=三束ブロック kn-keyword=三束ブロック END start-ver=1.4 cd-journal=joma no-vol=100 cd-vols= no-issue=3-4 article-no= start-page=351 end-page=360 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=1988 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Tissue cathepsin B activity and serum inhibitory factor　of cathepsin B activity in patients with liver cancer kn-title=肝癌の組織中カテプシンB活性と血清中カテプシンB活性阻害因子の動態とその臨床的意義 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Liver tissue cathepsin B (EC 3.4.22.1) activity was measured with N-benzyloxy-carbonyl-L-arginyl-L-arginine-4-methyl-7-coumarilamide (Z-Arg-Arg-MCA) as the substrate in order to clarify the role of this enzyme in tumor invasion or metastasis of liver cancer. Serum inhibitory factor of cathepsin B activity was also determined in cirrhotic patients with hepatocellular carcinoma and in patients with other liver diseases.Cathepsin B activity of liver cancer tissues in patients with lung metastasis was higher than that in non-cancerous tissue sourrounding the main tumor. The levels of serum inhibitory factor of cathepsin B activity in patients with hepatocellular carcinoma were lower than those in healthy subjects or non-malignant chronic liver diseases. Furthemore, in hepatocellular carcinoma patients with portal invasion, serum levels of inhibitory factor of cathepsin B activity were much lower than those with no portal invasion.The results suggest that cathepsin B activity participates in tumor invasion and metastasis of liver cancer due to imbalance of enzyme-inhibitor relationship. en-copyright= kn-copyright= en-aut-name=HashimotoMakoto en-aut-sei=Hashimoto en-aut-mei=Makoto kn-aut-name=橋本誠 kn-aut-sei=橋本 kn-aut-mei=誠 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学第一内科学数室 en-keyword=肝癌 kn-keyword=肝癌 en-keyword=カテプシンB kn-keyword=カテプシンB en-keyword=血清中カテプシンB阻害因子 kn-keyword=血清中カテプシンB阻害因子 en-keyword=浸潤 kn-keyword=浸潤 en-keyword=転移 kn-keyword=転移 END start-ver=1.4 cd-journal=joma no-vol=99 cd-vols= no-issue=1-2 article-no= start-page=15 end-page=23 dt-received= dt-revised= dt-accepted= dt-pub-year=1987 dt-pub=19870228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Radiotherapy of brain metastases from lung cancer kn-title=肺癌脳転移の放射線治療 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We studied the results of radiotherapy in 65 patients with brain metastases of lung cancer. In the 34 patients whose treatment consisted of radiotherapy alone, the median survival time was 164 days and the mean survival time was 210 days. Remission was achieved in 29 (85%) of these patients, indicating that radiotherapy was effective. A minimum radiation dose of 30 Gy was necessary to decrease neurological symptoms, and 40 Gy or more was considered to be desirable. Survival after radiotherapy appeared to be dependent largely on factors other than brain metastases such as the effectiveness of management of the primary lesion, the presence or the extent of metastases to other organs, and the patient's general condition. Our study suggests that greater efforts must be made for early detection and early treatment to achieve prolongation of as well as qualitative improvements in the survival time. en-copyright= kn-copyright= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=3 ORCID= en-aut-name=KashitaniNaoko en-aut-sei=Kashitani en-aut-mei=Naoko kn-aut-name=柏谷尚子 kn-aut-sei=柏谷 kn-aut-mei=尚子 aut-affil-num=4 ORCID= en-aut-name=MiyakeMasayoshi en-aut-sei=Miyake en-aut-mei=Masayoshi kn-aut-name=三宅正淑 kn-aut-sei=三宅 kn-aut-mei=正淑 aut-affil-num=5 ORCID= en-aut-name=YamamotoYoshio en-aut-sei=Yamamoto en-aut-mei=Yoshio kn-aut-name=山本淑雄 kn-aut-sei=山本 kn-aut-mei=淑雄 aut-affil-num=6 ORCID= en-aut-name=KanzakiNoriko en-aut-sei=Kanzaki en-aut-mei=Noriko kn-aut-name=神崎典子 kn-aut-sei=神崎 kn-aut-mei=典子 aut-affil-num=7 ORCID= en-aut-name=InoueNobuhiro en-aut-sei=Inoue en-aut-mei=Nobuhiro kn-aut-name=井上信浩 kn-aut-sei=井上 kn-aut-mei=信浩 aut-affil-num=8 ORCID= en-aut-name=NoriyasuToshiaki en-aut-sei=Noriyasu en-aut-mei=Toshiaki kn-aut-name=則安俊昭 kn-aut-sei=則安 kn-aut-mei=俊昭 aut-affil-num=9 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=10 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=11 ORCID= en-aut-name=MizutaAkihumi en-aut-sei=Mizuta en-aut-mei=Akihumi kn-aut-name=水田昭文 kn-aut-sei=水田 kn-aut-mei=昭文 aut-affil-num=12 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=13 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=radiotherapy kn-keyword=radiotherapy en-keyword=brain metastases kn-keyword=brain metastases en-keyword=lung cancer kn-keyword=lung cancer END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue=2 article-no= start-page=45 end-page=52 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Numerical Simulation of Quantum Systems -Dynamics of Electrons in Microstructures- en-subtitle= kn-subtitle= en-abstract= kn-abstract=Difficulties in simulating systems composed of classical and quantum particles lie in the treatment of the many-body interactions between quantum particles and the geometrical variety of configurations of classical particles. In order to overcome these difficulties, we have developed some numerical methods and applied them to simple cases. As for stationary states, the finite element method provides us with sufficient geometrical freedom. Combined with the Kohn-Sham equation based on the density functional theory, this method virtually satisfies our requirement. In order to investigate time-dependent phenomena, we apply the time-dependent Kohn-Sham equation. Adopting the finite difference method, we are able to follow the development of quantum many-body system. As an example, we estimate the effects of the potential height, the electric field, and many-body interactions in some transition processes in quantum wells coupled by a tunneling barrier. This example is important in itself in relation to semiconductor superlattices and also serves as a benchmark for quantum simulations, variety of geometry corresponding to that of classical particles. en-copyright= kn-copyright= en-aut-name=TotsujiHiroo en-aut-sei=Totsuji en-aut-mei=Hiroo kn-aut-name=東辻浩夫 kn-aut-sei=東辻 kn-aut-mei=浩夫 aut-affil-num=1 ORCID= en-aut-name=HashimotoSeiji en-aut-sei=Hashimoto en-aut-mei=Seiji kn-aut-name=橋本成仁 kn-aut-sei=橋本 kn-aut-mei=成仁 aut-affil-num=2 ORCID= en-aut-name=NaraShigetoshi en-aut-sei=Nara en-aut-mei=Shigetoshi kn-aut-name=奈良重俊 kn-aut-sei=奈良 kn-aut-mei=重俊 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical and Electronic Engineering affil-num=2 en-affil= kn-affil=Department of Electrical and Electronic Engineering affil-num=3 en-affil= kn-affil=Department of Electrical and Electronic Engineering END start-ver=1.4 cd-journal=joma no-vol=27 cd-vols= no-issue=1 article-no= start-page=55 end-page=64 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19921125 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Intrinsic Bistability of Coupled Quantum Wires: Localization due to Many-Body Effects en-subtitle= kn-subtitle= en-abstract= kn-abstract=The ground state of a system of electrons accumulated in a pair of coupled symmetric quantum wires is analyzed on the basis of density functional theory. It is shown that, in a domain of physical parameters, electrons are localized in either of wires. The main contribution to the total energy of this system comes from the Hartree energy, or the electrostatic energy, and the exchange-correlation energy between electrons. The ground state is determined by a competition between these contributions: We have symmetric electron distributions when the Hartree energy dominates and asymmetric (localized) states are realized in the opposite case. This kind of simple system with bistable electronic states may be applied to semiconductor memory devices. en-copyright= kn-copyright= en-aut-name=TotsujiHiroo en-aut-sei=Totsuji en-aut-mei=Hiroo kn-aut-name=東辻浩夫 kn-aut-sei=東辻 kn-aut-mei=浩夫 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=TachibanaHiroyuki kn-aut-sei=Tachibana kn-aut-mei=Hiroyuki aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=HashimotoSeiji kn-aut-sei=Hashimoto kn-aut-mei=Seiji aut-affil-num=3 ORCID= en-aut-name=NaraShigetoshi en-aut-sei=Nara en-aut-mei=Shigetoshi kn-aut-name=奈良重俊 kn-aut-sei=奈良 kn-aut-mei=重俊 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical and Electronic Engineering affil-num=2 en-affil= kn-affil=Department of Electrical and Electronic Engineering affil-num=3 en-affil= kn-affil=Department of Electrical and Electronic Engineering affil-num=4 en-affil= kn-affil=Department of Electrical and Electronic Engineering END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=3-4 article-no= start-page=281 end-page=285 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=199004 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Paternity testing in our department for last 11 years kn-title=我々の教室における親子鑑定の現況 en-subtitle= kn-subtitle= en-abstract= kn-abstract=From August 1978 to December 1989, 85 paternity testings were performed in our depart-ment. In 49 cases, each man was accused to be the father of an illegtimate child. In 24 cases, each child was accused to be an illegitimate child by the father. In 9 cases, each chid was sued for making sure to be a real child of a man. Paternity was excluded in 15 of the cases. en-copyright= kn-copyright= en-aut-name=NanikawaRyo en-aut-sei=Nanikawa en-aut-mei=Ryo kn-aut-name=何川凉 kn-aut-sei=何川 kn-aut-mei=凉 aut-affil-num=1 ORCID= en-aut-name=MoriyaFumio en-aut-sei=Moriya en-aut-mei=Fumio kn-aut-name=守屋文夫 kn-aut-sei=守屋 kn-aut-mei=文夫 aut-affil-num=2 ORCID= en-aut-name=NakaiMiyoko en-aut-sei=Nakai en-aut-mei=Miyoko kn-aut-name=中井三代子 kn-aut-sei=中井 kn-aut-mei=三代子 aut-affil-num=3 ORCID= en-aut-name=HashimotoYoshiaki en-aut-sei=Hashimoto en-aut-mei=Yoshiaki kn-aut-name=橋本良明 kn-aut-sei=橋本 kn-aut-mei=良明 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部法医学教室 en-keyword=親子鑑定 kn-keyword=親子鑑定 en-keyword=Paternity kn-keyword=Paternity en-keyword=卵生診断 kn-keyword=卵生診断 en-keyword=血液型 kn-keyword=血液型 en-keyword=遺伝形質 kn-keyword=遺伝形質 END start-ver=1.4 cd-journal=joma no-vol=78 cd-vols= no-issue=2-3 article-no= start-page=227 end-page=234 dt-received= dt-revised= dt-accepted= dt-pub-year=1966 dt-pub=19660330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=高利得心電図について en-subtitle= kn-subtitle= en-abstract= kn-abstract=A newly developed augmented electrocardiogram was tested. (xlO) Using this electrocardiogram. the P wave, PR interval and QT duration were studied. Utilization of the augmented electrocardiogram was reported. en-copyright= kn-copyright= en-aut-name=HaraokaSyoichi en-aut-sei=Haraoka en-aut-mei=Syoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=1 ORCID= en-aut-name=SatoMichihiko en-aut-sei=Sato en-aut-mei=Michihiko kn-aut-name=佐藤迪彦 kn-aut-sei=佐藤 kn-aut-mei=迪彦 aut-affil-num=2 ORCID= en-aut-name=ShiinaHiroshi en-aut-sei=Shiina en-aut-mei=Hiroshi kn-aut-name=椎名宏 kn-aut-sei=椎名 kn-aut-mei=宏 aut-affil-num=3 ORCID= en-aut-name=ItaniAkira en-aut-sei=Itani en-aut-mei=Akira kn-aut-name=井谷昭 kn-aut-sei=井谷 kn-aut-mei=昭 aut-affil-num=4 ORCID= en-aut-name=HashimotoHiroyuki en-aut-sei=Hashimoto en-aut-mei=Hiroyuki kn-aut-name=橋本宏之 kn-aut-sei=橋本 kn-aut-mei=宏之 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大産医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大産医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大産医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大産医学部第一内科教室 affil-num=5 en-affil= kn-affil=岡山大産医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=78 cd-vols= no-issue=2-3 article-no= start-page=211 end-page=225 dt-received= dt-revised= dt-accepted= dt-pub-year=1966 dt-pub=19660330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=肝循環動態に関する研究　第2編 肝リンパに関する研究-実験犬による検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=To study dynamics and physico-chemical properties of the hepatic lymph of normal dogs, cannulation of hepatic lymph duct was performed under nembutal anesthesia, and the lymph flowing out of the fistula was continuously collected. Similar experiments were also carried out on dogs with acute carbon tetrachloride poisoning. The results were as follows. 1. The average rate of hepatic lymph flow was 1.52cc per 10 minutes (0.07cc per 10 minutes per kilogram) in normal mongrel dogs. 2. In dogs with acute carbon tetrachloride poisoning, not only the average rate of hepatic lymph flow but also the pressure and the diameter of lymphatic vessels of the liver was remarkably increased. 3. More or less cellular elements, mainly lymphocytes, even some red blood cells, were detected in the liver lymph of intact dogs. A marked increase of red blood cells were observed in the lymph of dogs with acute carbon tetrachloride poisoning. This fact indicated that the lymph-canaliculus of the liver was open to red blood corpuscles in part, and this phenomenon was manifested by carbon tetrachloride poisoning. 4. The liver lymph contained approximately similar amount of protein to the serum and all the protein fractions as observed in the serum. The A/G quotient was usually higher in the liver lymph than in the serum. These data would suggest that all fractions of seum protein are able to leak out from the sinusoid walls and enter the lymphatic system of the liver. Furthermore, albumin produced by the hepatic cells may directly enter this lymphatic system. 5. The hepatic lymph contained a greater amount of glucose than serum, whereas the amount of bilirubin, cholesterol and alkaline phosphatase in hepatic lymph was smaller than that in serum. The results are of interest when the transfer of metabolites between hepatic cells and lymph or blood is considered. en-copyright= kn-copyright= en-aut-name=HashimotoHiroyuki en-aut-sei=Hashimoto en-aut-mei=Hiroyuki kn-aut-name=橋本宏之 kn-aut-sei=橋本 kn-aut-mei=宏之 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=78 cd-vols= no-issue=2-3 article-no= start-page=201 end-page=210 dt-received= dt-revised= dt-accepted= dt-pub-year=1966 dt-pub=19660330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=肝循環動態に関する研究　第1編 肝疾患時における肝内酸素消費に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=By means of catheterization of hepatic veins, hepatic oxygen consumption was estimated on patients with chronic viral hepatitis (37 cases), precirrhosis (4 cases) and cirrhosis of the liver (13 cases). The oxygen consumption was calculated from the difference of oxygen content between the hepatic artery and the hepatic vein multiplied with the total hepatic blood flow. The results werc as follows: 1. The oxygen content of the arterial blood showed no significant difference in groups of chronic hepatitis, precirrhosis and cirrhosis of the liver. 2. Similarly, the arterio-venous oxygen difference, as measured without any regard of hepatic shunt flow, did not differ significantly in those three groups. Decreased hepatic blood flow, therefore induced a decreased amount of hepatic oxygen consumption; the decrease of hepatic blood flow was not accompanied with the compensatory increase of the plausible arterio-venous oxygen difference. 3. The arterio-venous oxygen difference calculated with a reference to the influences of hepatic shunt flow was estimated by multiplication of arterio-venous oxygen difference to the ratio of total hepatic blood flow and effective hepatic blood flow. The difference was found to be increased in a majority of the cases of liver cirrhosis, indicating the oxygen extraction by the hepatic cells in cirrhosis was significantly increased. Conversely, oxygen saturation of non-shunted hepatic venous blood was markedly decreased in cirrhosis. Thus the increased oxygen extraction by the cirrhotic hepatic cells occured in the state of low oxygen tension. The hepatic oxygen consumption was found to be maintained as great as possible by increasing the arterio-venous oxygen difference calculated with a reference to the influence of hepatic shunt flow. 4. The increase of the arterio-venous oxygen difference calculated with a reference to the influence of hepatic shunt flow was closely related to the abnormalities of the hepatic hemodynamics, histological changes and hepatic disfunctions. en-copyright= kn-copyright= en-aut-name=HashimotoHiroyuki en-aut-sei=Hashimoto en-aut-mei=Hiroyuki kn-aut-name=橋本宏之 kn-aut-sei=橋本 kn-aut-mei=宏之 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=1-2 article-no= start-page=165 end-page=176 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=199002 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Magnetic resonance image database system and its clinical applications kn-title=MR 画像データベースシステムの開発とその臨床応用に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A magnetic resonance (MR) image detabase system has been developed. The purpose of this paper is to present this system and its application. It consists of an image processing system and database system to handle data of clinical cases and a medical knowledge base. Using the image processing system and the database system with stored data of clinical cases, the MR image data of cases can be retrieved by diagnosis as well as ID number, patient's name, etc., and MR images can be processed. By using the database system with the medical knowledge base, differential diagnoses can be offered. en-copyright= kn-copyright= en-aut-name=NoriyasuToshiaki en-aut-sei=Noriyasu en-aut-mei=Toshiaki kn-aut-name=則安俊昭 kn-aut-sei=則安 kn-aut-mei=俊昭 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=MRI kn-keyword=MRI en-keyword=database kn-keyword=database en-keyword=medical image kn-keyword=medical image en-keyword=knowledge base kn-keyword=knowledge base en-keyword=PACS kn-keyword=PACS END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=4 article-no= start-page=455 end-page=462 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Medico-legal autopsy cases related to poisons and drugs kn-title=近年における薬毒物の検出された司法解剖例について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Poisons and drugs other than alcohol and CO were detected in 17 of all judicial autopsy cases in the Department of Legal Medicine, Okayama University Medical School during the last 12 years. We report 7 cases from the forensic toxicological viewpoint. 1) lethal overdose of Sedes A, 2) fatal poisoning due to biperiden, thioridazine and nitrazepam taken simultaneously, 3) fatal DDVP poisoning, 4) fatal paraquat poisoning, 5) hypoxic death by inhalation of liquefied petroleum gas, 6) fatal shock induced by sulpyrine, and 7) fatal shock induced by ketoprofen. en-copyright= kn-copyright= en-aut-name=MoriyaFumio en-aut-sei=Moriya en-aut-mei=Fumio kn-aut-name=守屋文夫 kn-aut-sei=守屋 kn-aut-mei=文夫 aut-affil-num=1 ORCID= en-aut-name=NanikawaRyo en-aut-sei=Nanikawa en-aut-mei=Ryo kn-aut-name=何川凉 kn-aut-sei=何川 kn-aut-mei=凉 aut-affil-num=2 ORCID= en-aut-name=HashimotoYoshiaki en-aut-sei=Hashimoto en-aut-mei=Yoshiaki kn-aut-name=橋本良明 kn-aut-sei=橋本 kn-aut-mei=良明 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部法医学教室 en-keyword=Toxicology kn-keyword=Toxicology en-keyword=Fatal poisoning kn-keyword=Fatal poisoning en-keyword=Fatal shock kn-keyword=Fatal shock en-keyword=Poisons and drugs kn-keyword=Poisons and drugs en-keyword=Drugs in autopsy cases kn-keyword=Drugs in autopsy cases END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=4 article-no= start-page=435 end-page=444 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical studies on serum factors in patients with bronchal asthma Part 2. Changes in serum levels of complement factors, C3 (β(1c/1A)), & C4(β(1E)) in patients with bronchial asthma kn-title=気管支喘息における体液因子に関する研究 第2編 補体系C3 (β(1c/1A)), C4(β(1E)) 値の変動について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Serum C3 and C4 levels were measured in 23 healthy subjects and 105 patients with bronchial asthma, by an immunodiffusion method using M-Partigen Plates. The serum levels of C4 were significantly increased in patients over 60 years old compared to the healthy subjects. The levels of C3 were significantly higher in male cases than in female cases with bronchial asthma. The serum levels of C3 and C4 in asthma patients with infectious type, in severe cases and in cases with steroid therapy were within the normal limits during non-attack periods, but significantly increased during attack periods. In asthmatic patients with mixed and infectious type, and in mild and severe cases, a significant correlation was observed between the serum levels of C3 and C4 during their non-attack periods. en-copyright= kn-copyright= en-aut-name=IshibashiKen en-aut-sei=Ishibashi en-aut-mei=Ken kn-aut-name=石橋健 kn-aut-sei=石橋 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=気管支喘息 kn-keyword=気管支喘息 en-keyword=C3 kn-keyword=C3 en-keyword=C4 kn-keyword=C4 END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=11-12 article-no= start-page=1215 end-page=1224 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Immobilization of denitrifying bacteria using photo-crosslinkable resin prepolymer and some of its properties kn-title=光硬化性樹脂プレポリマーを用いる脱窒菌の固定化に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The denitrifiers isolated from the activated sludge of night soil treatment plant were immobilized using a photo-crosslinkable resin prepolymer. Denitrifying activity was strongly inhibited during the first period but the activity was increased in the medium containing nitrate and recovered after 1 day. Acetate was an effective hydrogen source and soap was also effective. Methanol could not serve as a hydrogen source. The optimum pH for denitrification by the immobilized bacteria was 7.0 for nitrite and 7.5 for nitrate, and the optimum temperature ranged 30℃ to 40℃. The lowest CH3COONa/NOx-N ratio nessary for getting the highest activity was 4 for nitrite (BOD/NO2-N＝2) and 5 for nitrate (BOD/NO3-N＝2.5). Photo-crosslinkable resin prepolymer gels exhibited stable denitrification activity to the secondarily treated sewage contained 70mg/l of soap. en-copyright= kn-copyright= en-aut-name=ItadaniTsutomu en-aut-sei=Itadani en-aut-mei=Tsutomu kn-aut-name=板谷勉 kn-aut-sei=板谷 kn-aut-mei=勉 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部細菌学教室 en-keyword=脱窒菌 kn-keyword=脱窒菌 en-keyword=固定化 kn-keyword=固定化 en-keyword=脱窒素 kn-keyword=脱窒素 en-keyword=排水処理 kn-keyword=排水処理 END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=11-12 article-no= start-page=1207 end-page=1214 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Basic study on nitrification and the BOD removal of the sewage using immobilized activated sludge kn-title=固定化活性汚泥を用いる排水処理実験 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Activated sludge obtained from the night soil treatment plant was immobilized using acrylamide and nitrification and the BOD removal of the sewage were studied by using the immobilized activated sludge which was packed in a single treatment tank. The findings indicated that the ratio of nitrification in the immobilized gel tank was larger than that in the free activated sludge tank in every operation period, and the rate of BOD removal in the immobilized gel tank was roughly equal to that in the free activated sludge tank in this condition. The findings indicated that the application of immobilized activated sludge to the sewage treatment enabled the sewage treatment process to be more efficiency and compact. en-copyright= kn-copyright= en-aut-name=ItadaniTsutomu en-aut-sei=Itadani en-aut-mei=Tsutomu kn-aut-name=板谷勉 kn-aut-sei=板谷 kn-aut-mei=勉 aut-affil-num=1 ORCID= en-aut-name=HiraiYosikazu en-aut-sei=Hirai en-aut-mei=Yosikazu kn-aut-name=平井義一 kn-aut-sei=平井 kn-aut-mei=義一 aut-affil-num=2 ORCID= en-aut-name=KanemasaYasuhiro en-aut-sei=Kanemasa en-aut-mei=Yasuhiro kn-aut-name=金政泰弘 kn-aut-sei=金政 kn-aut-mei=泰弘 aut-affil-num=3 ORCID= en-aut-name=NagamachiEiko en-aut-sei=Nagamachi en-aut-mei=Eiko kn-aut-name=長町栄子 kn-aut-sei=長町 kn-aut-mei=栄子 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部細菌学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部細菌学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部細菌学教室 affil-num=4 en-affil= kn-affil=順正短期大学保健科 en-keyword=固定化活性汚泥 kn-keyword=固定化活性汚泥 en-keyword=固定化 kn-keyword=固定化 en-keyword=硝化 kn-keyword=硝化 en-keyword=排水処理 kn-keyword=排水処理 END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=4 article-no= start-page=419 end-page=434 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical studies on serum factors in patients with bronchal asthma Part 1. Changes in α(1)-Antitrypsin and α(1)-Acid glycoprotein levels in patients with bronchial asthma and other respiratory diseases kn-title=気管支喘息における体液因子に関する研究 第1編 血清糖蛋白 (α(1)-Antitrypsin, α(1)-Acid glycoprotein) の変動について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Serum α(1)-Antitrypsin (α(1)-AT) and α(1)-Acid glycoprotein (α(1)-AG) levels were measured in 34 healthy subjects, 167 patients with bronchial asthma and 82 cases with other respiratory diseases. The serum levels of α(1)-AT were significantly increased in patients over 40 years old and the levels of α(1)-AG were significantly higher in patients over 50 years old compared to the those under 50 years old. The serum levels of α(1)-AT and α(1)-AG were significantly more increased in asthmatic patients with mixed and infective type during asymptomatic periods than in healthy subjects. The levels of α(1)-AT were significantly higher in patients with mild and moderate asthma than in healthy subjects. The levels of α(1)-AG were also significantly higher in mild and severe asthmatic patients than in healthy subjects. Patients with severe asthma showed more increased levels of α(1)-AT during attack periods compared to that during non-attack periods. The levels of α(1)-AT and α(1)-AG in asthma patients with steroid therapy were within normal limits during the non-attack periods, but significantly increased during the attack periods. In asthmatic patients with mixed type, infectious type, severe type and steroid therapy, a correlation was observed between the serum levels of α(1)-AT and α(1)-AG during their attack periods. en-copyright= kn-copyright= en-aut-name=IshibashiKen en-aut-sei=Ishibashi en-aut-mei=Ken kn-aut-name=石橋健 kn-aut-sei=石橋 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=気管支喘息 kn-keyword=気管支喘息 en-keyword=α(1)-Antitrypsin kn-keyword=α(1)-Antitrypsin en-keyword=α(1)-Acid glycoprotein kn-keyword=α(1)-Acid glycoprotein END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=4 article-no= start-page=373 end-page=386 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical study on idiopathic thrombocytopenic purpura (ITP) Part 2. Analysis of the treatment of ITP and the value of colchicine therapy for the steroid resistant ITP kn-title=特発性血小板減少性紫斑病 (ITP)に関する臨床的研究 第2編 ITP の治療効果の解析とステロイド難反応性ITPに対するコルヒチン療法の意義について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Clinical effects of steroid and colchicine therapy in 49 patients with ITP especially the refractory cases were evaluated in comparison with splenectomy and danazol therapy. There were 27(55%) steroid resistant patients who could not maintain platelet counts of 5×10(4)/μl with prednisolone doses of less than 10mg/day. Among the 16 steroid resistant patients treated with colchicine, there were 3 patients with complete remission and 3 others who had good to excellent response, that is, 6(37.5%) improved overall. This therapy was more effective than splenectomy (33.3%) and danazol (25%). Colchicine was did not effective in patients who did not respond to prednisolone, but was useful when patients showed at least a transient rise of the platelet count with prednisolone. In many cases, a response to colchicine was seen after a month, and in the patients who failed to show a rise in the platelet count after 2 months of colchicine therapy, no benefit was seen even when the therapy was continued. Colchicine is advantageous in the treatment of the steroid resistant ITP over the immunosuppressive agents or high-dose γ-globulin that are expensive and produce only a transient rise in the platelet count. en-copyright= kn-copyright= en-aut-name=TsurumiNaokazu en-aut-sei=Tsurumi en-aut-mei=Naokazu kn-aut-name=鶴見尚和 kn-aut-sei=鶴見 kn-aut-mei=尚和 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=steroid resistant ITP kn-keyword=steroid resistant ITP en-keyword=colchicine kn-keyword=colchicine en-keyword=danazol kn-keyword=danazol en-keyword=splenectomy kn-keyword=splenectomy END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=1-2 article-no= start-page=23 end-page=36 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=199002 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Medico-legal aspects of traumatic injures-Rrport of 13 autopsy cases- kn-title=損傷の法医学的考察―司法解剖13例について― en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this paper we present 13 autopsy cases on interest in medico-legal traumatology. The cases are as follows : 1)two cases of incomplete cardiac rupture dur to thoracic trauma, 2)rupture of herniated large intestine due to abdominal trauma, 3)large incised wounds on the side of the neck by a small kitchen knife, 4)a homicidal case with similar wounds that accompanied self-inflicted wounds, 5)a homicidal case accompanied by multiple stab wounds on the chest, 6)an accidental death skewered by a slender metallic stick, 7)special fatal shotgun injuries, 8)a homicidal case accompanid by various burns by an electric hair-dryer, iron and ciga-rettes, 9)two murder cases by a metallic baseball bat, 10)a suicidal case due to a fall from a high place, and 11)a severely disrupted victim of a road traffic accident. en-copyright= kn-copyright= en-aut-name=NanikawaRyo en-aut-sei=Nanikawa en-aut-mei=Ryo kn-aut-name=何川凉 kn-aut-sei=何川 kn-aut-mei=凉 aut-affil-num=1 ORCID= en-aut-name=HashimotoYoshiaki en-aut-sei=Hashimoto en-aut-mei=Yoshiaki kn-aut-name=橋本良明 kn-aut-sei=橋本 kn-aut-mei=良明 aut-affil-num=2 ORCID= en-aut-name=MoriyaFumio en-aut-sei=Moriya en-aut-mei=Fumio kn-aut-name=守屋文夫 kn-aut-sei=守屋 kn-aut-mei=文夫 aut-affil-num=3 ORCID= en-aut-name=MiyaishiSatoru en-aut-sei=Miyaishi en-aut-mei=Satoru kn-aut-name=宮石智 kn-aut-sei=宮石 kn-aut-mei=智 aut-affil-num=4 ORCID= en-aut-name=NakaiMiyoko en-aut-sei=Nakai en-aut-mei=Miyoko kn-aut-name=中井三代子 kn-aut-sei=中井 kn-aut-mei=三代子 aut-affil-num=5 ORCID= en-aut-name=YangXu en-aut-sei=Yang en-aut-mei=Xu kn-aut-name=徐揚 kn-aut-sei=徐 kn-aut-mei=揚 aut-affil-num=6 ORCID= en-aut-name=GuoChun Gang en-aut-sei=Guo en-aut-mei=Chun Gang kn-aut-name=郭春鋼 kn-aut-sei=郭 kn-aut-mei=春鋼 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部法医学教室 en-keyword=Criminal injuries kn-keyword=Criminal injuries en-keyword=Injuries and utensils kn-keyword=Injuries and utensils en-keyword=Traumatic injuries kn-keyword=Traumatic injuries en-keyword=Medico-legal traumatology kn-keyword=Medico-legal traumatology END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=5-6 article-no= start-page=701 end-page=711 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the pathogenesis of interstitial pneumonia of collagen vascular diseases Part 2. Examination of interleukin 2 receptor in interstitial pneumonia of collagen vascular diseases kn-title=膠原病肺の病態に関する研究　第2編　膠原病肺における血清中および気管支肺胞洗浄液中 soluble IL-2 receptor の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Abnormality of cellular immunity has been reported in the pathogenesis of collagen vascular diseases (CVD). IL-2 and IL-2 receptors play important roles as immunological regulation in CVD. In this study, the soluble forms of IL-2 receptor (sIL-2R) and IL-2 receptor positive lymphocytes (CD25) were analyzed to evaluate the role of IL-2R in the pathogenesis of interstitial pneumonia (IP) of CVD such as RA, SLE, polymyositis/dermatomyositis (PM/DM), and PSS and idiopathic interstitial pneumonia (IIP) as a disease control. High levels of sIL-2R were found in sera of patients with IP of CVD. The level of soluble IL-2R in sera of RA without IP correlated with the disease activity of the joints, while the level of sIL-2R in sera of RA with IP was higher than in that of RA without IP. Soluble IL-2R in bronchoalveolar lavage fluind (BALF) was also measured and the level was higher in IP with CVD. There were fewer IL-2R positive lymphocytes in the peripheral blood of CVD with IP than in the normal controls or IIP cases, although the serum level of sIL-2R was higher in CVD with IP and IIP than in the normal controls. These findings indicate that actibve immunological activities involving IL-2/IL-2R/sIL-2R systems play an important role in the pathogenesis of IP of CVD. en-copyright= kn-copyright= en-aut-name=YokotaSatoshi en-aut-sei=Yokota en-aut-mei=Satoshi kn-aut-name=横田聡 kn-aut-sei=横田 kn-aut-mei=聡 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=collagen vascular disease kn-keyword=collagen vascular disease en-keyword=interstitial pneumonia kn-keyword=interstitial pneumonia en-keyword=bronchoalveolar lavage kn-keyword=bronchoalveolar lavage en-keyword=soluble IL-2 receptor kn-keyword=soluble IL-2 receptor en-keyword=IL-2 receptor positive lymphocyte kn-keyword=IL-2 receptor positive lymphocyte END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=4 article-no= start-page=257 end-page=266 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effects of SMA-SOD on brain damage induced by complete global brain ischemia in dogs kn-title=イヌの完全全脳虚血後の脳障害に及ぼすSMA-SOD の効果に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The effects of stylene maleinic acid butyl ester superoxide dismutase (SMA-SOD) on the brain damage induced by ischemia were studied in dogs. Eighteen minutes of cerebral ischemia was produced by clamping the ascending aorta with aorta-atrial and aorta-femoral vein bypass circuit. SMA-SOD(10mg/kg) was administered just after the initiation of recirculation. Dogs were divided into, control group and SMA-SOD group. In each group, cerebral blood flow (CBF) and intracranial pressure (ICP) were measured for 7 hours after ischemia, and neurologic outcome was evaluated up to 7 days after ischemia. Furthermore, extravasation of evans blue dye (EB, 100mg/kg) were observed 30 minutes after ischemia. SMA-SOD increased CBF during the hyperemia, and improved both delayed post-ischemic hypoperfusion (DHP) and neurologic outcomes. Extravasation of EB were recognized in the control group, but not in the SMA-SOD group. In conclusion, vasogenic edema might play a role in the elevation of ICP besides the hyperemia, and SMA-SOD improved neurologic outcome by prevention of edema, and improvement of DHP. Furthermore, free radicals might play a role in the appearance of ischemic brain damage. en-copyright= kn-copyright= en-aut-name=TakedaYoshimasa en-aut-sei=Takeda en-aut-mei=Yoshimasa kn-aut-name=武田吉正 kn-aut-sei=武田 kn-aut-mei=吉正 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部麻酔・蘇生学教室 en-keyword=SMA-SOD kn-keyword=SMA-SOD en-keyword=神経学的予後 kn-keyword=神経学的予後 en-keyword=血流脳関門 kn-keyword=血流脳関門 en-keyword=遅発性脳血流減少 kn-keyword=遅発性脳血流減少 en-keyword=イヌ kn-keyword=イヌ END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=1-2 article-no= start-page=199 end-page=207 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Early increase in blood brain barrier permeability to evans blue dye after complete global brain ischemia in dogs kn-title=イヌの完全全脳虚血後の血液脳関門の透過性に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The influence of reperfusion after complete global brain ischemia (CGBI) on blood brain barrier (BBB) permeability to evans blue dye (EB) was studied in dogs. The various durations of CGBI, from 10 to 18 minutes, were produced by clamping the ascending aorta with the aorta to the right atrium and the aorta to the femoral vein bypass circuit. Dogs were divided into four groups according to the duration of CGBI : dogs in group A, B, C, and D(n=6, in each group) suffered 10, 12, 15, and 18 minutes of CGBI, respectively. EB was injected 15 minutes after the reperfusion, and extravasation of EB in the cerebral cortex. thalamus, hippocampus, cerebellum and the brain stem were observed 30 minutes after the reperfusion. In this study, cerebral blood flow (CBF) and intracranial pressure (ICP) were also measured for the first 20 minutes after the reperfusion. Extravasation of EB were observed in three dogs except for group A, and a tendency toward extravasation of EB in the cerebellum was recognized in group C and D. Reactive hyperemia and increase in ICP within 20 minutes after the reperfusion were also observed. In conclusion, not only ischemia but also the reactive hyperemia might increase BBB permeability. en-copyright= kn-copyright= en-aut-name=KurodaTomonori en-aut-sei=Kuroda en-aut-mei=Tomonori kn-aut-name=黒田友則 kn-aut-sei=黒田 kn-aut-mei=友則 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部麻酔・蘇生学教室 en-keyword=完全全脳虚血 kn-keyword=完全全脳虚血 en-keyword=再灌流 kn-keyword=再灌流 en-keyword=血液脳関門 kn-keyword=血液脳関門 en-keyword=エバンスブルー kn-keyword=エバンスブルー en-keyword=イヌ kn-keyword=イヌ END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=1-2 article-no= start-page=173 end-page=181 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of heparin-urokinase on the brain damage induced by complete global brain ischemia kn-title=完全全脳虚血後の脳障害に対するへパリン・ウロキナーゼ併用療法の効果に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The effect of heparin-urokinase (H-U) on the prevention of brain damage induced by ischemia was evaluated in 31 dogs subjected to an 18 min of complete global brain ischemia. Complete brain ischemia was produced by clamping the ascending aorta with aorto-atrial and aorto-femoral bypass formation. Post-ischemic cerebral blood flow (CBF) and other hemodynamic parameters were measured for 7 hours after ischemia in 15 dogs (acute study). Neurologic outcome was evaluated for 7 days after ischemia in 16 dogs (chronic study). Fifteen minutes after restoration of circulation to the brain, an intravenous bolus of heparin 100 I.U./kg and urokinase 3000 I.U./kg, was given, followed by continuous intravenous infusion of heparin 0.25 I.U./kg/min and urokinase 8.3 I.U./kg/min for 6 hours. H-U significantly improved both post-ischemic CBF and neurologic outcome. H-U was effective in treating brain damage when given 15 min after ischemia. These results suggest that H-U improved both post ischemic CBF and neurologic outcome owing to amelioration of the deterioration of microcirculation. en-copyright= kn-copyright= en-aut-name=MorimotoNaoki en-aut-sei=Morimoto en-aut-mei=Naoki kn-aut-name=森本直樹 kn-aut-sei=森本 kn-aut-mei=直樹 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部麻酔・蘇生学教室 en-keyword=完全全脳虚血 kn-keyword=完全全脳虚血 en-keyword=へパリン kn-keyword=へパリン en-keyword=ウロキナーゼ kn-keyword=ウロキナーゼ en-keyword=No-reflow 現象 kn-keyword=No-reflow 現象 en-keyword=遅発性脳血流減少 kn-keyword=遅発性脳血流減少 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=5-6 article-no= start-page=591 end-page=599 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Mitral valve replacement with preservation of the posterior mitral apparatus for mitral stenosis : An analysis of postoperative cardiac function and its correlations with ultrastructural changes in the myocardial cells kn-title=僧帽弁狭搾症に対する後尖温存術式後の左心機能―心筋変性度との関連― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Postoperative cardiac function was evaluated by dynamic exercise echocardiography in 36 cases with mitral stenosis, and electron microscopic examination of the LV myocardial cells was also carried out. Ultrastructual changes of the LV myocardial cells were graded into scores (EM-score). EM-scores correlated with % FS (r=-0.54), mVcf (r=-0.60) at rest and % FS (r=-0.54), mVcf (r=-0.50) after exercise. In 36 cases, 25 cases underwent conventional MVR (group Ⅰ) and 11 underwent MVR with preservation of the posterior mitral apparatus (group Ⅱ). When postoperative cardiac function was compared in 13 cases less than 4 of EM-score in group Ⅰ because EM-scores were less than 4 in all cases in group Ⅱ, no difference was observed in two groups except for mVcf at rest. The vaulues of % △FS and % △mVcf in group Ⅰ were better than those in group Ⅱ. This suggests that preservation of the hypertrophic and sclerotic subvalvular tissue in mitral stenosis disturebs the LV diastolic wall motion. en-copyright= kn-copyright= en-aut-name=ShichijoTakeshi en-aut-sei=Shichijo en-aut-mei=Takeshi kn-aut-name=七条健 kn-aut-sei=七条 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=僧帽弁狭搾症 kn-keyword=僧帽弁狭搾症 en-keyword=後尖温存術式 kn-keyword=後尖温存術式 en-keyword=運動負荷 kn-keyword=運動負荷 en-keyword=術後心機能 kn-keyword=術後心機能 en-keyword=心筋変性度 kn-keyword=心筋変性度 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=5-6 article-no= start-page=489 end-page=499 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The usefulness of transvaginal ultrasonography and MRI in endometrial carcinama : Evaluating myomertrial and cervical invasion kn-title=子宮体癌に対する経腟走査超音波断層法とMRIの有用性について―筋層浸潤と頚部浸潤の評価― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Between October, 1988 and March, 1991, twenty-mine patients with endometrial carcinoma bad both transvaginal ultrasonography (TVUS) and magnetic resonance imaging (MRI) performed following hysterectomy at the Departmetn of Gynecology and Obstetrics, Okayama University Medical School. The findings were compared with the pathological findings to determine the usefulness of each method. The sensitivity of dectecthing myometrial invasion was 100% by TVUS and 96% by MRI. The accuracy was 86% by each method. The depth of myometrial invasion was classified into 3 degrees [no myometrial invasion, superficial invasion (≤1/2), deep invasion (>1/2)]. The correct diagnostic rate was 86% by TVUS and MRI. The minimum width and the minimum/maximum width ratio of the intact myometrium obtained by each method in the pathological deep invasion group were significantly lower than those obtained in the other two groups (p<0.01). The sensitivity, the accuracy and the specificity of detecting cervical invasion were 89%, 93% and 95% by both methods. There was no difference between TVUS and MRI for diagnosing myometrial and cerical invasion of endometrial carcinoma. en-copyright= kn-copyright= en-aut-name=YoshiharaEisuke en-aut-sei=Yoshihara en-aut-mei=Eisuke kn-aut-name=吉原英介 kn-aut-sei=吉原 kn-aut-mei=英介 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部産科婦人科学教室 en-keyword=子宮体癌 kn-keyword=子宮体癌 en-keyword=経腟走査超音波断層法 kn-keyword=経腟走査超音波断層法 en-keyword=MRI kn-keyword=MRI en-keyword=筋層浸潤 kn-keyword=筋層浸潤 en-keyword=頚部浸潤 kn-keyword=頚部浸潤 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=3-4 article-no= start-page=399 end-page=412 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studis on the pathogenesis of idiopathic interstitial pneumonia Part 1. Clinical features including various laboratory and roentogenologic findings in regard to the response to the treatment kn-title=特発性間質性肺炎の病態に関する研究　第1編　臨床集計による特発性間質性肺炎の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Clinical features, laboratory findings including hematological and biochemical exmination, pulmanary function test and chest x-ray findings of patients with idiopathic interstital pneumonia (IIP) were analyzed to determine the response to steroid therapy. Sixty three patients with IIP were analyzed in comparison with 43 patietns of interstitial pneumonia due to various diseases such as collagen disease, tuberculosis and chronic obstructive lung disease. Almost half of the patients with IIP were treated with steroids and improvement of interstitial pneumonia was shown only in the patients given steroid therapy. The improvement with steroid therapy was shown to the 50% in acute form of IIP, 32.1% in chronic form of IIP and 36.8% in total. Furthermore, the response of steroid therapy was better in patients with a relatively high oxygen level and high vital capacity and with no honeycombing on the chest X-ray film. These findings indicate the therapeutic effectivesess of steroid therapy in some patients and it should be started in the early stage of the clinical of IIP to obtain a good response rate. en-copyright= kn-copyright= en-aut-name=FujitaMichio en-aut-sei=Fujita en-aut-mei=Michio kn-aut-name=藤田道雄 kn-aut-sei=藤田 kn-aut-mei=道雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=idiopathic interstitial pneumonia kn-keyword=idiopathic interstitial pneumonia en-keyword=Steroid therapy kn-keyword=Steroid therapy en-keyword=Prognosis of IIP kn-keyword=Prognosis of IIP en-keyword=Chest x-ray finding kn-keyword=Chest x-ray finding END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=3-4 article-no= start-page=341 end-page=354 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Adequate antiplatelet therapy on the basis of individual variation in platelet aggregation in the late period after cardiovascular surgery kn-title=血小板凝集能の個体差を考慮した至適抗血小板療法―心臓血管外科手術後遠隔期における検討― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Platelet aggregation was studied on 670 samples of 20 healthy controls and 279 patients in the late period after cardiovascular surgery. Aggregating agents used were 0.5 and 2.0μM ADP as well as 2mM arachidonic acid (AA). Among the healthy controls, a maximum aggregation rate over 18% (ADP 0.5μM) was considered hyperaggregability, those under 47% (ADP 2μM) or under 78% (AA 2mM) consid-ered hypoaggregability. Maximun aggregation rate in patients not given antiplatelt agents widely varied from hyperaggregability to hypoaggregability. There was a positive correlation botween the first sample and the second one gained from each patient. This suggested that individual variation existed on platelet aggregation. Maximum aggregation rate significatly decreased by ticlopidine for ADP and by aspirin for AA. Both ADP and AA should be used for platelet aggregation. Comparison among three groups of different ticlopidine doses revealed that the doses should be decided on the basis of platelet aggregation for each patient. Thrombotic or hemorrhagic complications were observed in only 9 cases. Four of 7 cases of thrombotic complicatiion showed hyperaggregability and only 1 case showed hypoaggregability. Both cases of hemorrhagic complication showed hypoaggregability. These findings suggest that indication for antiplatelet therapy and doses of antiplatelet agent should be decided in consideration of individual variation on platelet aggregation. en-copyright= kn-copyright= en-aut-name=TsushimaYoshimasa en-aut-sei=Tsushima en-aut-mei=Yoshimasa kn-aut-name=津島義正 kn-aut-sei=津島 kn-aut-mei=義正 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=血小板凝集能 kn-keyword=血小板凝集能 en-keyword=抗血小板薬 kn-keyword=抗血小板薬 en-keyword=ADP kn-keyword=ADP en-keyword=アラキドン酸 kn-keyword=アラキドン酸 en-keyword=術後遠隔期 kn-keyword=術後遠隔期 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=3-4 article-no= start-page=297 end-page=310 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical and histological studies on steroid-induced avascular necrosis of the femoral head, especially in ststemic lupus erythematosus kn-title=ステロイド性大腿骨頭壊死症の病態に関する研究―全身性エリテマトーデス(SLE)を中心に― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Clinical and radiological studies were performed on avascular necrosis of the femoral head (ANF) in 220 hips 140 patients including 51 hips of 28 patients with systemic lupus erythe-matosus (SLE group). Sixty-nine hips of 41 patients wee treated with corticosteroid adminis-tration (S group) and 100 hips of 71 patients without corticosteroid administration (Non-S group). All patients with SLE were treated with corticosteroid adminstration. Thirty-one femoral heads (11 heads of SLE group, 9 heads of S group and 11 heads of Non-S group) were resected at operations nad studied histologically. Seventy-seven hips at an early stage showed that collapse of the femoral heads occurred in 80% without 3 years and no differences were found among these group. In the SLE group, bilateral involvement, multiple bone necrosis and predilection for young females were apparent. Collapse of the femoral head and subcapital fractures were more frequently seen in the SLE group. Histologically, almost all heads even in the SLE group showed repair process such as enchondral ossification and appositional bone formation, while the heads with subcapital fracture showed no such no such changes. en-copyright= kn-copyright= en-aut-name=UsuiMasaaki en-aut-sei=Usui en-aut-mei=Masaaki kn-aut-name=臼井正明 kn-aut-sei=臼井 kn-aut-mei=正明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部整形外科学教室 en-keyword=大腿骨頭壊死症 kn-keyword=大腿骨頭壊死症 en-keyword=全身性エリテマトーデス(SLE) kn-keyword=全身性エリテマトーデス(SLE) en-keyword=病態 kn-keyword=病態 END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue=1 article-no= start-page=1 end-page=7 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070310 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Lectures on the Development of Teaching Plans and Teaching Materials Tried in the Science Education Class in Master's Course, Okayama University kn-title=岡山大学大学院理科教育専攻で行った教材・授業案開発講義の試み en-subtitle= kn-subtitle= en-abstract=This is a report of the new type of lectures on the development of teaching plans and teaching materials attempted in the science class in the Master's Course, Okayama University. The lectures were conducted in collaboration of the graduate students and the academic staffs in the science education course, and the science teachers of the attached school of Okayama University. The graduate students were grouped into two teams of five or six people, assigned to decide on themes, prepare and practice the development of teaching plans and teaching materials. They conducted their activities discussing problems with people of different experience and specialty, thus developing the ability to jointly propose and solve problems at schools in future. kn-abstract=岡山大学大学院教育学研究科の理科教育専攻の講義として、教材開発・授業案開発をテーマとした新しい講義を試みたのでその報告を行う。本講義は、理科教育講座に所属する大学院生、理科教育講座の大学教員、附属学校の理科関係の教諭が三者協働で進めることが特徴である。課題設定、教材開発を含めた実践準備および実践を院生チームを組み遂行させ、さらに経験や専門性の異なる人材と論議を重ねて活動を進めることを通じ、将来、協働で学校現場の課題提案・解決を行うことのできる能力を養うことを目標とした。 en-copyright= kn-copyright= en-aut-name=InadaYoshihiko en-aut-sei=Inada en-aut-mei=Yoshihiko kn-aut-name=稲田佳彦 kn-aut-sei=稲田 kn-aut-mei=佳彦 aut-affil-num=1 ORCID= en-aut-name=KakiharaSeiji en-aut-sei=Kakihara en-aut-mei=Seiji kn-aut-name=柿原聖治 kn-aut-sei=柿原 kn-aut-mei=聖治 aut-affil-num=2 ORCID= en-aut-name=KitaMasakazu en-aut-sei=Kita en-aut-mei=Masakazu kn-aut-name=喜多雅一 kn-aut-sei=喜多 kn-aut-mei=雅一 aut-affil-num=3 ORCID= en-aut-name=YamashitaNobuhiko en-aut-sei=Yamashita en-aut-mei=Nobuhiko kn-aut-name=山下信彦 kn-aut-sei=山下 kn-aut-mei=信彦 aut-affil-num=4 ORCID= en-aut-name=IshikawaTeruhiko en-aut-sei=Ishikawa en-aut-mei=Teruhiko kn-aut-name=石川彰彦 kn-aut-sei=石川 kn-aut-mei=彰彦 aut-affil-num=5 ORCID= en-aut-name=OguraHisakazu en-aut-sei=Ogura en-aut-mei=Hisakazu kn-aut-name=小倉久和 kn-aut-sei=小倉 kn-aut-mei=久和 aut-affil-num=6 ORCID= en-aut-name=AndoMotonori en-aut-sei=Ando en-aut-mei=Motonori kn-aut-name=安藤元紀 kn-aut-sei=安藤 kn-aut-mei=元紀 aut-affil-num=7 ORCID= en-aut-name=KusachiIsao en-aut-sei=Kusachi en-aut-mei=Isao kn-aut-name=草地功 kn-aut-sei=草地 kn-aut-mei=功 aut-affil-num=8 ORCID= en-aut-name=KatoKuranoshin en-aut-sei=Kato en-aut-mei=Kuranoshin kn-aut-name=加藤内蔵進 kn-aut-sei=加藤 kn-aut-mei=内蔵進 aut-affil-num=9 ORCID= en-aut-name=YoshiokaTsutomu en-aut-sei=Yoshioka en-aut-mei=Tsutomu kn-aut-name=吉岡勉 kn-aut-sei=吉岡 kn-aut-mei=勉 aut-affil-num=10 ORCID= en-aut-name=KawataYuki en-aut-sei=Kawata en-aut-mei=Yuki kn-aut-name=河田有紀 kn-aut-sei=河田 kn-aut-mei=有紀 aut-affil-num=11 ORCID= en-aut-name=HirakawaMotoshi en-aut-sei=Hirakawa en-aut-mei=Motoshi kn-aut-name=平山元士 kn-aut-sei=平山 kn-aut-mei=元士 aut-affil-num=12 ORCID= en-aut-name=HashimotoSeiji en-aut-sei=Hashimoto en-aut-mei=Seiji kn-aut-name=橋本誠治 kn-aut-sei=橋本 kn-aut-mei=誠治 aut-affil-num=13 ORCID= en-aut-name=AkazakiTetsuya en-aut-sei=Akazaki en-aut-mei=Tetsuya kn-aut-name=赤崎哲也 kn-aut-sei=赤崎 kn-aut-mei=哲也 aut-affil-num=14 ORCID= en-aut-name=HigashiNobuhiko en-aut-sei=Higashi en-aut-mei=Nobuhiko kn-aut-name=東伸彦 kn-aut-sei=東 kn-aut-mei=伸彦 aut-affil-num=15 ORCID= en-aut-name=BecchakuAkio en-aut-sei=Becchaku en-aut-mei=Akio kn-aut-name=別役昭夫 kn-aut-sei=別役 kn-aut-mei=昭夫 aut-affil-num=16 ORCID= affil-num=1 en-affil= kn-affil=岡山大学教育学部 affil-num=2 en-affil= kn-affil=岡山大学教育学部 affil-num=3 en-affil= kn-affil=岡山大学教育学部 affil-num=4 en-affil= kn-affil=岡山大学教育学部 affil-num=5 en-affil= kn-affil=岡山大学教育学部 affil-num=6 en-affil= kn-affil=岡山大学教育学部 affil-num=7 en-affil= kn-affil=岡山大学教育学部 affil-num=8 en-affil= kn-affil=岡山大学教育学部 affil-num=9 en-affil= kn-affil=岡山大学教育学部 affil-num=10 en-affil= kn-affil=岡山大学教育学部附属小学校 affil-num=11 en-affil= kn-affil=岡山大学教育学部附属小学校 affil-num=12 en-affil= kn-affil=岡山大学教育学部附属小学校 affil-num=13 en-affil= kn-affil=岡山大学教育学部附属中学校 affil-num=14 en-affil= kn-affil=岡山大学教育学部附属中学校 affil-num=15 en-affil= kn-affil=岡山大学教育学部附属中学校 affil-num=16 en-affil= kn-affil=岡山大学教育学部附属中学校 en-keyword=大学院講義 (Science Education Class in the Master's Course) kn-keyword=大学院講義 (Science Education Class in the Master's Course) en-keyword=附属学校 (Attached School) kn-keyword=附属学校 (Attached School) en-keyword=授業実践 (education practice) kn-keyword=授業実践 (education practice) en-keyword=教材開発 (Development of Teaching Materials) kn-keyword=教材開発 (Development of Teaching Materials) en-keyword=授業案開発 (Development of Teaching Plans) kn-keyword=授業案開発 (Development of Teaching Plans) END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=9-10 article-no= start-page=923 end-page=929 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199210 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Combined resection of lung cancer and invaded aorta with the use of simple temporary bypass : A case reort kn-title=肺癌における簡易式一時バイパス法を用いた大動脈合併切除の一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Left pneumonectomy and concomitant resection of the invaded aorta were performed by the simple temporary bypass method. The patient was a 59-year-old male with the chief complaint of left thoracic pain. The 57×43×35 mm tumor was in a region centering on segment 6 of the left lung and had infiltrated the descending aorta. It was diagnosed as T4NOMO, Stage IIIb. A bypass for blood flow was established between the aortic arch avobe the invasion and the left femoral artery, after ligation of the pulmonary artery and vein and closure of the left bronchial stump. Vascular blocking forceps were applied to the descending aorta above and below the tumor infiltration, and two thirds of the circumference of the invaded aortic wall, 4.0×3.0 cm, along with the tumor, was resected. Reconstruction was performed with an 18mm Cooly double velour graft. Blood pressure was monitored with a pressure probe inserted into the right femoral artery. It did not fall below 60 mmHg during the operation. Local recurrence was observed 10 montns post-operatively, and the patient is now receiving radiation therapy. en-copyright= kn-copyright= en-aut-name=InoueFumiyuki en-aut-sei=Inoue en-aut-mei=Fumiyuki kn-aut-name=井上文之 kn-aut-sei=井上 kn-aut-mei=文之 aut-affil-num=1 ORCID= en-aut-name=KamikawaYasuaki en-aut-sei=Kamikawa en-aut-mei=Yasuaki kn-aut-name=上川康明 kn-aut-sei=上川 kn-aut-mei=康明 aut-affil-num=2 ORCID= en-aut-name=NaomotoYoshio en-aut-sei=Naomoto en-aut-mei=Yoshio kn-aut-name=猶本良夫 kn-aut-sei=猶本 kn-aut-mei=良夫 aut-affil-num=3 ORCID= en-aut-name=GouchiAkira en-aut-sei=Gouchi en-aut-mei=Akira kn-aut-name=合地明 kn-aut-sei=合地 kn-aut-mei=明 aut-affil-num=4 ORCID= en-aut-name=OritaKunzo en-aut-sei=Orita en-aut-mei=Kunzo kn-aut-name=折田薫三 kn-aut-sei=折田 kn-aut-mei=薫三 aut-affil-num=5 ORCID= en-aut-name=HataTakato en-aut-sei=Hata en-aut-mei=Takato kn-aut-name=畑隆登 kn-aut-sei=畑 kn-aut-mei=隆登 aut-affil-num=6 ORCID= en-aut-name=KuinoseMasahiko en-aut-sei=Kuinose en-aut-mei=Masahiko kn-aut-name=杭ノ瀬昌彦 kn-aut-sei=杭ノ瀬 kn-aut-mei=昌彦 aut-affil-num=7 ORCID= en-aut-name=NanbaHirofumi en-aut-sei=Nanba en-aut-mei=Hirofumi kn-aut-name=難波宏文 kn-aut-sei=難波 kn-aut-mei=宏文 aut-affil-num=8 ORCID= en-aut-name=TaniguchiGyou en-aut-sei=Taniguchi en-aut-mei=Gyou kn-aut-name=谷口堯 kn-aut-sei=谷口 kn-aut-mei=堯 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=6 en-affil= kn-affil=心臓病センター榊原病院外科 affil-num=7 en-affil= kn-affil=心臓病センター榊原病院外科 affil-num=8 en-affil= kn-affil=心臓病センター榊原病院外科 affil-num=9 en-affil= kn-affil=心臓病センター榊原病院外科 en-keyword=簡易式一時バイパス kn-keyword=簡易式一時バイパス en-keyword=大動脈合併切除 kn-keyword=大動脈合併切除 en-keyword=進行性肺癌 kn-keyword=進行性肺癌 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=9-10 article-no= start-page=915 end-page=922 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199210 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Development of double cancer in small cell lung cancer patients treated with intensive chemotherapy kn-title=肺小細胞癌化学療法実施例における重複癌の発生に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Development of double cancer was evaluated in 337 small cell lung cancer patients who had received intensive chemotherapy with or without radiotherapy. Of them, 14 patients (4.2%) developed a second malignancy: non-small cell lung cancer in six, stomach cancer in four, acute myelogenous leukemia in two, liver cancer in one, and esophagus cancer in one. The relative risk for the development of double cancer calculated by person-year method utilizing age and sex adjusted cancer incidence in Japan was 2.75-fold (P<0.01). The risk of non-small cell lung cancer (8.75-fold) and acute myelogenous leukemia (37.82-fold) was particularly high. The cumulative risk for the development of double cancer was 2.0% at 1 year, 4.1% at 2 years, 14.3% at 3 years, and 100% at 8.1 years. Of 27 patients who survived disease-free for more than 2 years, 10 patients died; five patients (50%) died of double cancer, two died of infectious disease, and only three patients died from recurrent small cell lung cancer. These findings indicate that a cautious follow-up program for the detection of double cancer is indicated in patients with small cell lung cancer. en-copyright= kn-copyright= en-aut-name=MiyakeKenichi en-aut-sei=Miyake en-aut-mei=Kenichi kn-aut-name=三宅賢一 kn-aut-sei=三宅 kn-aut-mei=賢一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=肺小細胞癌 kn-keyword=肺小細胞癌 en-keyword=化学療法 kn-keyword=化学療法 en-keyword=重複癌 kn-keyword=重複癌 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=1-2 article-no= start-page=107 end-page=115 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Anticoagulant effect of nafamostat mesilate (FUT) and cepharanthin on the small-caliber prosthesis implantation in the small venous system kn-title=メシル酸ナファモスタットとセファランチンの併用による小口径静脈再建後早期における抗血栓作用に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The anticoagulant effect of nafamostat mesilate(FUT, a protease inhibitor) plus cepharanthin (CE) after small-caliber graft implantation into the canine jugular veins was compared with that of heparin (HE) or urokinase (UK). Twenty-four dogs were used in this study. Sauvage EXS Dacron grafts 5mm in diameter were implanted into external jugular veins. Immediately after impantation, continuous administration of drugs was started through posterior auricular veines. Coagulation test were carried out serially during perfusion. Three hours after implantation, the grafts were removed and examined macro-and microscopically. The dogs were divided into 4 groups : 1)Control group ; 2)UK group (2000u/kg/hr) ; 3)HE group (0.25mg/kg/hr) ; and 4)FUT plus CE group, FUT (0.3mg/kg/hr) plus CE (0.7mg/kg/hr). All grafts were thrombosed in the control group and UK group. However, no thrombus was found in the HE group anf FUT plus CE group. Coagulation tests revealed that fibrinogen and AT-Ⅲ decreased significantly in the UK group (p<0.05), ACT and APTT was gradually prolonged in the HE group (p<0.05), and there was no significant change in the FUT plus CE group. These findings suggest that FUT plus CE may not only decrease early thrombus formation, but may also maintain the balance of the coagulation system. The combination of FUT plus CE may be useful anticoagulant therapy during the postoperative period when the risk of bleeding remains. en-copyright= kn-copyright= en-aut-name=OkanoKazuo en-aut-sei=Okano en-aut-mei=Kazuo kn-aut-name=岡野和雄 kn-aut-sei=岡野 kn-aut-mei=和雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=抗血栓作用 kn-keyword=抗血栓作用 en-keyword=メシル酸ナファモスタット kn-keyword=メシル酸ナファモスタット en-keyword=セファランチン kn-keyword=セファランチン en-keyword=小口径人工血管 kn-keyword=小口径人工血管 en-keyword=静脈再建 kn-keyword=静脈再建 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=1-2 article-no= start-page=83 end-page=95 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on laser photocoagulation for retinopathy of prematurity kn-title=レーザー光凝固による未熟児網膜症の治療に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Forty eyes in twenty-two cases in the active phase of retinopathy of prematurity were treated with laser photocagulation. Thiry (93.7%) of the 32 eyes in type I and intermediate type were found in the cicartrical phase grade 1. In type Ⅱ in which cryocautery was used as combination therapy, only 2 eyes (25.0%) were found in grade 1, 2 eyes (25.0%) in grade 2, 1 eye (12.5%) in grade 4 and 3 eyes (37.5%) in grade 5. All 21 eyes in which photocoagulation was performed up to the middle of stage 3 were found in grade 1 (100%). However, among 11 eyes in which photocoagulation were performed in late stage 3, 9 eys (81.8%) were found in grade 1, and 2 eyes (18.2%) in grade 2. In conclusion, if adequate laser photocoagulation is performed in avascular ares at the middle of stage 3 of type Ⅰ and intermediate type, treatment in cicartrical phase grade 1 is possible. Laser photocoagulation is clearly more effective than the xenon are photocoagula-tion or cryocautery. However, in type Ⅱ it is difficult to control the condition by photocagulation alone, and early diagnosis followed by combination therapy using cryocautery is reqired. en-copyright= kn-copyright= en-aut-name=OhtakiChiaki en-aut-sei=Ohtaki en-aut-mei=Chiaki kn-aut-name=大滝千秋 kn-aut-sei=大滝 kn-aut-mei=千秋 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部眼科学教室 en-keyword=未熟児網膜症 kn-keyword=未熟児網膜症 en-keyword=レーザー光凝固 kn-keyword=レーザー光凝固 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=7-8 article-no= start-page=789 end-page=795 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The relationships between physique and throwing ability in high school baseball players kn-title=高校野球選手における形態と投能力の関係 en-subtitle= kn-subtitle= en-abstract= kn-abstract=There is little information on anthropometric measures (i. e., length, breadth and girth of body's parts) related to throwing ability. To clarify the influence of the physique on the throwing ability, the relationships between physique and throwing distance, as well as ball speed were investigated. The subjects were fourty-nine high school baseball players, and thirty-eight high school volleyball players, football players and canoeists served as a control group. The throwing distance was significantly related to lean body mass (r=.290), chest girth (r=.416), upper arm girth (r=.307), abdominal girth (r=.288), thigh girth (r=.327) and lower leg girth (r=.285) in baseball players group (p<0.05-0.01). A significant relationship between the throwing distance and foot length in control group (r=.329, p<0.05) was demonstrated. Significant relationships between ball speed and standing height in the baseball players group (r=.354, p<0.01) and that between ball speed and Impedance in the control group (r=-.288, p<0.05) were ovserved. These findings indicate that the throwing distance is influenced by quantity of body muscle in baseball players. There was no relation between physique and throwing ability in unskilled players. en-copyright= kn-copyright= en-aut-name=UchidaHayato en-aut-sei=Uchida en-aut-mei=Hayato kn-aut-name=内田勇人 kn-aut-sei=内田 kn-aut-mei=勇人 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学教室 en-keyword=野球選手 kn-keyword=野球選手 en-keyword=形態 kn-keyword=形態 en-keyword=遠投距離 kn-keyword=遠投距離 en-keyword=ボールスピード kn-keyword=ボールスピード en-keyword=Impedance kn-keyword=Impedance END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=7-8 article-no= start-page=763 end-page=775 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the role of neutrophils in intractable asthma Part 1. Leukotriene and superoxide production of neutrophils kn-title=難治性喘息における好中球の役割に関する研究　第1編　好中球からの Leukotrienes 産生能及び superoxide 産生能に関する検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The role of neutrophils migrated in the sputum and bronchoalveolar lavage fluid of intractable asthmatics is not difficult to understand. The production of leukotrienes (LTs) and superoxide stimulated by the calcium ionophores (CaI) from neutrophil-rich fraction of 29 intractable, 70 non-intractable asthmatics and 18 healthy subjects was examined by high performance liquid chromatography and a cytochrome C reduction method. Significantly larger amounts of LTC(4) and LTB(4) were produced by CaI in the neutrophil-rich fraction from asthematics, than in that from the healthy subjects (p<0.01). Moreover, a significantly larger amounts of LTC(4) was producted in the fraction obtained from the intractable asthmatics than in that from the non-intractable asthmatics (p<0.05). However, there was no significant difference in LTB(4) production between the two groups of asthmatics. The production of superoxide by concanavalin A was significantly increased in the neutrophil-rich fraction from prednisolone-within-10mg-dependent asthmatics than in those from prednisolone-over-10mg-dependent patients (p<0.01). There were correlations between the LTC(4) and LTB(4) production, and also between LTB(4) and superoxide production. LTs and superoxide released from inflammatory cells, especially neutrophils, may play an important role in the pathgenesis of intractable asthma. en-copyright= kn-copyright= en-aut-name=ShimizuIkki en-aut-sei=Shimizu en-aut-mei=Ikki kn-aut-name=清水一紀 kn-aut-sei=清水 kn-aut-mei=一紀 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=難治性喘息 kn-keyword=難治性喘息 en-keyword=好中球 kn-keyword=好中球 en-keyword=ロイコトリエン kn-keyword=ロイコトリエン en-keyword=スーパーオキサイド kn-keyword=スーパーオキサイド END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=7-8 article-no= start-page=747 end-page=761 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Chemical and physiological changes of serum and thoracic-duct lymph in the dog with experimental obstructive jaundice and/or disorder of liver circulation kn-title=実験的閉塞性黄疸および肝循環障害における血清と胸管リンパ液組成の変動に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A long-term study on the chemical and physiological changes of serum and thoracic-duct lymph in the dog with a ligated common bile duct and/or artificial liver circulation was performed. The influencee of ligation of the common bile duct appeared earlier in the thoracic-duct lymph than in the serum. The portal pressure did not increase in the dog with a ligated common bile duct, but the lymph flow of the thoracic duct was 3 times that before ligation, which would prevent the rapid stagnation of bile pigment in the liver. The portal pressure was not elevated after ligation of the hepatic artery. The cholesterol level in the thoracic-duct lymph was about half of that in the serum. In the dog with ligature of the common bile duct, the serum total cholesterol level was elevated with the elevation of serum bilirubin, whereas that in the lymph of the thoracic duct was not elevated with the elevation of the bilirubin level in the lymph. These findings suggested that cholesterol would not easily enter into the lymphatic route. The serum GPT level increased during the first week after ligation of the hepatic artery, and decreased thereafter. However, after ligation of the common bile duct, the GPT level increased for several weeks after the first week of ligation. The pattern of GPT by both ligations seemed to be cross-crossed. The marked change in the total bilirubin level in the lymph of the thoracic duct suggested its close relation with the lymphatic system. It was proved possible to secure a tube into the thoracic duct for over three weeks by the use of a U-type connector and jacket-type plaster cast. en-copyright= kn-copyright= en-aut-name=UedaYuzo en-aut-sei=Ueda en-aut-mei=Yuzo kn-aut-name=上田祐造 kn-aut-sei=上田 kn-aut-mei=祐造 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=実験的肝障害 kn-keyword=実験的肝障害 en-keyword=閉塞性黄疸 kn-keyword=閉塞性黄疸 en-keyword=肝循環障害 kn-keyword=肝循環障害 en-keyword=胸管リンパ液 kn-keyword=胸管リンパ液 en-keyword=胸管カヌレーション kn-keyword=胸管カヌレーション END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=5-6 article-no= start-page=549 end-page=560 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=1994 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical studies on plasma cyclic nucleotide levels in acute leukemia kn-title=急性白血病における血漿cyclic nucleotides動態に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Plasma levels of cyclic nucleotides were measured in 71 patients with acute leukemia [50 patients with acute nonlymphocytic leukemia (ANLL), five patients with hypoplastic leuke-mia, and 16 patients with acute lymphocytic leukemia (ALL)], five patients with myelodysplas-tic syndrome (MDS), and 47 healthy volunteers. The cyclic GMP (c-GMP) level, cyclic AMP (c-AMP) level, and c-AMP/c-GMP ratio in healthy volunteers were 15.74±5.10 pmol/ml, 3.20±1.15 pmol/ml and 5.39±2.18, respectively. In the patients with untreated acute leukemia other than hypoplastic leukemia, c-GMP levels were significantly elevated (ANLL : 11.31±13.61 pmol/ml ; ALL : 10.66±7.23 pmol/ml) and c-AMP/c-GMP ratios were significantly reduced (ANLL : 2.01±1.03 ; ALl : 1.66±1.03). These values normalized at remission, than increased or decreased again with recurrence of the disease. Although patients with MDS showed normal c-GMP levels or c-AMP/c-GMP rations, these values were increased or decreased when progression to acute leukemia occurred. There was correlation between c-GMP levels and peripheral leukocyte counts (r=0.429,p<0.05), plasma c-GMP levels and peripheral leukemic cell counts (r=0.412,p<0.05), c-AMP/c-GMP rations and peripheral leukocyte counts (r=-0.577,p<0.05), c-AMP/c-GMP rations and periph-eral leukemic cell counts (r=-0.512,p<0.05), and c-AMP/c-GMP rations and periph-eral leukemic cell counts (r=-0.512,p<0.05), and c-AMP/c-GMP rations and maximum counts of colonies derived from leukemic blast progenitors (r=-0.996,p<0.01). Since plasma levls of cyclic nucleotides reflect the leukemic cell proliferation, measurement of these nucleotides was considered useful for monitoring leukemic cell volume. en-copyright= kn-copyright= en-aut-name=NonakaKenichi en-aut-sei=Nonaka en-aut-mei=Kenichi kn-aut-name=野中研一 kn-aut-sei=野中 kn-aut-mei=研一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=血漿 cyclic nucleotides kn-keyword=血漿 cyclic nucleotides en-keyword=急性白血病 kn-keyword=急性白血病 en-keyword=低形成型白血病 kn-keyword=低形成型白血病 END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=5-6 article-no= start-page=527 end-page=541 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=1993 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Regional cerebral blood flow in the patient with brain tumor kn-title=局所脳血流測定法による脳腫瘍の循環動態に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Regional cerebral blood flow (rCBF) was measured with xenon-enhanced CT(Xe-CT) in 21 cases of intracranial tumors (13 meningiomas, 5 gliomas, 3 metastatic brain tumors). Peritumoral edema was graded as mild, moderate or severe based on the extent of edema on CT and MRI. According to intratumoral blood flow distribution patterns, three patterns were classified as central type with relatively high blood flow at the center of the tumor, homogeneous type with an almost homegeneous blood flow distribution, and marginal type with relatively high blood flow at the periphery of the tumor. High grade astrocytoma and metastatic brain tumor showed marginal type blood flow and moderate or severe edema except in one case. Five meningiomas with severe peritumoral edema revealed marginal type blood flow and four with mild peritumoral edema showed central type blood flow, except for one cace. No correlation was found between the extent of peritumoral edema and histological subtype, tumor size, locaton, duration of clinical history, vascularization on angiogram, and mean blood flow in the tumor. These results suggest that blood flow distribution patterns within the tumor may affect the extension of peritumoral edema. Pre-and postoperative rCBFs were evaluated with Xe-CT and IMP-SPECT in 7 cases. mean rCBF of peritumoral edema was 6.2ml/100g/min preoperatively, and discrepancy between rCBF on Xe-CT and that on IMP-SPECT was shown in the remote cortical region ipsilateral to the tumor. Postoperative rCBF revealed an improved blood flow in both adjacent and remote areas, suggesting that the decreased blood flow associated with brain tumors might be relieved after surgery. en-copyright= kn-copyright= en-aut-name=TsuchidaShohei en-aut-sei=Tsuchida en-aut-mei=Shohei kn-aut-name=槌田昌平 kn-aut-sei=槌田 kn-aut-mei=昌平 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部脳神経外科学教室 en-keyword=brain tumor kn-keyword=brain tumor en-keyword=regional cerebral blood flow kn-keyword=regional cerebral blood flow en-keyword=SPECT kn-keyword=SPECT en-keyword=Xe-CT kn-keyword=Xe-CT END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=5-6 article-no= start-page=399 end-page=408 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=1993 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A nutritional and metabolic assessment of a cardiopulmonary bypass technique without donor blood kn-title=無血体外循環法における栄養，代謝の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A nutritional and metabolic assessment of a cardiopulmonary bypass technique without donor blood was made in 23 patients undergoing open heart surgery (non-donor blood group). For comparison, 14 patients receiving cardiopulmonary bypass with donor blood prime (donor blood group) were also evaluated. 1)Serum transferrin level showed significantly more rapid recovery in the non-donor blood group compared to the donor blood group on the 7th post operative day. 2)Total protein, serum albumin, arm muscle circumference, creatinine-height-index and triceps skin fold showed no significant differences between the two groups. 3)Total lymphocyte count as an indicator of immune status showed a significant increase in the non-donor blood group on the 3rd post operative day. 4)The recovery from the postoperative hypermetabolic state was more smoothly achieved in the non-donor group blood group than in the donor blood group. In conclusion, the cardiopulmonary bypass technique without donor blood is a safe and effective means of open heart surgery, not only saving blood but also preventing undue, infectious and/or hypersensitive diseases. en-copyright= kn-copyright= en-aut-name=HigashiRyouhei en-aut-sei=Higashi en-aut-mei=Ryouhei kn-aut-name=東良平 kn-aut-sei=東 kn-aut-mei=良平 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=無血体外循環法 kn-keyword=無血体外循環法 en-keyword=栄養評価 kn-keyword=栄養評価 en-keyword=代謝亢進 kn-keyword=代謝亢進 en-keyword=血液希釈 kn-keyword=血液希釈 END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=3-4 article-no= start-page=291 end-page=302 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=1993 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effect of hyperbaric oxygen on lipid peroxidation, antioxidant activity and guanidines and amino acids metabolism in rat brain kn-title=高気圧酸素曝露のラット脳内の脂質過酸化，活性酸素消去能，グアニジノ化合物およびアミノ酸代謝におよぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Lipid peroxidation, free radical contents, antioxidant activity, guanididno compound metabolism and changes in amino acid contents in rat brain were studied to clarify the effect of a clinically relevant dose of hyperbaric oxygen (HBO). Seven-week-old rats were exposed to HBO at 3 atmosphere absolute for 2 hours. An increase in thiobarbituric acid reactive substances and carbon centered radicals was observed after exposure. Supreoxide dismutase-like activity also increased. The measurement of guanidino compounds revealed a significant rise in arginine and guanidinoacetic acid (GAA) levels. Since arginase activity decreased while there was no significant alteration in arginine : glycine-amidinotransferase activity, these changes in enzyme activities seem to cause the increase of arginine and GAA levels. In relation to guanidino compound metabolism, the amino acid contents were determined. An increase in glutamine and taurine levels were observed and these seemed to favor the defense mechanism. These data suggested that ongoing lipid peroxidation in the brain was caused by HBO, and that the defense mechanism against the oxidative stress was activated in response. en-copyright= kn-copyright= en-aut-name=ItohTakehiko en-aut-sei=Itoh en-aut-mei=Takehiko kn-aut-name=伊藤武彦 kn-aut-sei=伊藤 kn-aut-mei=武彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属分子細胞医学研究施設神経情報学部門 en-keyword=hyperbaric oxygen kn-keyword=hyperbaric oxygen en-keyword=lipid peroxidation kn-keyword=lipid peroxidation en-keyword=antioxidants kn-keyword=antioxidants en-keyword=guanidino compounds kn-keyword=guanidino compounds en-keyword=amino acids kn-keyword=amino acids END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=11-12 article-no= start-page=933 end-page=943 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19931231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Biphasic opening of the blood-brain barrier to horseradish peroxidase after 18 minutes of complete global brain ischemia in dogs kn-title=イヌの18分間完全全脳虚血後の血液脳関門の経時的透過性変化に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The ability of horseradish peroxidase (HRP) to cross the blood-brain barrier (BBB) was studied in dogs by electron microscopy after 18 minutes of complete global brain ischemia (CGBI). The first BBB opening occurred 30 minutes after the recirculation was established ; This was associated with the increase of HRP-containing pinocytotic vesicles (HRP-PV), but there was no endothelial cell damage. There was no BBB opening 3, 6, and 24 hours after the recirculation ; This was determined by absence of increase in HRP-PV and lack of endothelial cell damage. The second BBB opening occurred 48 hours after the recirculation ; This was associated with disruption of the tight junction of the endothelial cell, lack of increased HRP-PV and destruction of the endothelial cell menbrane. These results suggest that the first BBB opening is due to increased pinocytotic transport by reactive hyperemia and the second BBB opening is due to endothelial cell damage by CGBI itself. en-copyright= kn-copyright= en-aut-name=ShimodaYutaka en-aut-sei=Shimoda en-aut-mei=Yutaka kn-aut-name=下田豊 kn-aut-sei=下田 kn-aut-mei=豊 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部麻酔・蘇生学教室 en-keyword=完全全脳虚血 kn-keyword=完全全脳虚血 en-keyword=血液脳関門 kn-keyword=血液脳関門 en-keyword=HRP kn-keyword=HRP END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=3-4 article-no= start-page=299 end-page=304 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=1994 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of broncholithiasis complicating hemoptysis kn-title=喀血を主訴に来院した気管支結石の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 62-year-old male was admitted because of hemoptysis. The chest X-ray showed an infiltrative shadow in the right upper lung field. Tomograms and CT scans also showed an infiltrative shadow and small calcifications in the same field. Examination by bronchoscopy revealed bronchial bleeding from the depth of the right B1b. Although the detailed view was unclear due to bleeding, we did not find any growth or any mucosal abnormality. We examined only the bronchial washing cytology. The result was Papanicolaou class Ⅱ. However, we could not rule out malignancy, so we decided to perform a right upper lobectomy. A bron-cholith was seen in the B1b and a hematoma was also seen on its periphery. The stone components were calcium carbonate (74%) and calcium phosphate (26%), suggesting that the stone was caused by mucus retention. en-copyright= kn-copyright= en-aut-name=IshiiYasunori en-aut-sei=Ishii en-aut-mei=Yasunori kn-aut-name=石井泰則 kn-aut-sei=石井 kn-aut-mei=泰則 aut-affil-num=1 ORCID= en-aut-name=InoueFumiyuki en-aut-sei=Inoue en-aut-mei=Fumiyuki kn-aut-name=井上文之 kn-aut-sei=井上 kn-aut-mei=文之 aut-affil-num=2 ORCID= en-aut-name=ShinRyuhan en-aut-sei=Shin en-aut-mei=Ryuhan kn-aut-name=慎隆範 kn-aut-sei=慎 kn-aut-mei=隆範 aut-affil-num=3 ORCID= en-aut-name=IshizukaShinji en-aut-sei=Ishizuka en-aut-mei=Shinji kn-aut-name=石塚真示 kn-aut-sei=石塚 kn-aut-mei=真示 aut-affil-num=4 ORCID= en-aut-name=FunakiNaoto en-aut-sei=Funaki en-aut-mei=Naoto kn-aut-name=舟木直人 kn-aut-sei=舟木 kn-aut-mei=直人 aut-affil-num=5 ORCID= en-aut-name=MuramatsuTomoyoshi en-aut-sei=Muramatsu en-aut-mei=Tomoyoshi kn-aut-name=村松友義 kn-aut-sei=村松 kn-aut-mei=友義 aut-affil-num=6 ORCID= en-aut-name=KamikawaYasuaki en-aut-sei=Kamikawa en-aut-mei=Yasuaki kn-aut-name=上川康明 kn-aut-sei=上川 kn-aut-mei=康明 aut-affil-num=7 ORCID= en-aut-name=TanakaNoriaki en-aut-sei=Tanaka en-aut-mei=Noriaki kn-aut-name=田中紀章 kn-aut-sei=田中 kn-aut-mei=紀章 aut-affil-num=8 ORCID= en-aut-name=OritaKunzo en-aut-sei=Orita en-aut-mei=Kunzo kn-aut-name=折田薫三 kn-aut-sei=折田 kn-aut-mei=薫三 aut-affil-num=9 ORCID= en-aut-name=OdaKoji en-aut-sei=Oda en-aut-mei=Koji kn-aut-name=小田晧二 kn-aut-sei=小田 kn-aut-mei=晧二 aut-affil-num=10 ORCID= en-aut-name=SeoKenji en-aut-sei=Seo en-aut-mei=Kenji kn-aut-name=瀬尾憲治 kn-aut-sei=瀬尾 kn-aut-mei=憲治 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=10 en-affil= kn-affil=小田病院外科 affil-num=11 en-affil= kn-affil=健照会セオ病院 en-keyword=気管支結石 kn-keyword=気管支結石 en-keyword=喀血 kn-keyword=喀血 en-keyword=Broncholithiasis kn-keyword=Broncholithiasis en-keyword=Hemoptysis kn-keyword=Hemoptysis END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=1-2 article-no= start-page=205 end-page=216 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of lithium carbonate on brain injury induced by complete global brain ischemia in dogs kn-title=完全全脳虚血後の脳障害に対する炭酸リチウムの効果に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The efficacy of lithium carbonate (Li) in preventing ischemic brain injury was evaluated in 36 dogs in a vegetative state. The dogs were subjected to 18 minutes of complete global brain ischemia and diveded into the following three groups ; control group (n=12), L-Ⅰ group (n=12), and L-Ⅱ group (n=12). In the L-Ⅰand L-Ⅱgroups, dogs were administered Li (10mg/kg) immediately after the end of ischemia (post-treatment). Only in the L-Ⅱ group, dogs were administered Li (100mg/kg) orally one day before the ischemic insult (pre-treatment). In each group, nuerologic outcome was evaluated for seven days after ischemia, and morphological changes in hippocampal CA1 pyramidal cells, small to medium-sized striatal neurons and cerebellar Purkinje cells were evaluated at day seven. In the L-Ⅱ group, neutrologic outcome was significantly better than that in the control group, and morphological improvement was recognized. Pre-treatment with Li might improve both neurologic and morphologic outcomes due to powerful inhibition of the stimulated phosphoinositide turnover during ishchemia. These fingings suggest that the stimulated phosphoinositide turnover during and immediately after ischemia might play an important role in brain injury induced by 18 minutes of complete global brain ischemia. en-copyright= kn-copyright= en-aut-name=YaidaYutaka en-aut-sei=Yaida en-aut-mei=Yutaka kn-aut-name=八井田豊 kn-aut-sei=八井田 kn-aut-mei=豊 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部麻酔・蘇生学教室 en-keyword=完全全脳虚血 kn-keyword=完全全脳虚血 en-keyword=イノシトールリン脂質作動系 kn-keyword=イノシトールリン脂質作動系 en-keyword=炭酸リチウム kn-keyword=炭酸リチウム END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=11-12 article-no= start-page=919 end-page=932 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19931231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Superoxide anion (O(2)(－)) production by neutrophils in myelodysplastic syndrome (MDS) kn-title=Myelodysplastic syndrome (MDS) における好中球スーパーオキサイド産生能に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Myelodysplastic syndrome (MDS) are hematological disorders with the potential of progressing to acute leukemia. MDS patients occasionally die of infection despite the absence of severe pancytopenia prior to overt leukemia. Superoxide anion (O(2)(－)) production leads to intracellular bactericidal activity by neutrophils, particularly in an oxygen-dependent system. In this paper, O(2)(－) production by neutrophils in 15 MDS patients [11 patients with refractory anemia with excess of blasts (RAEB) and 4 patients with RAEB in transformation (RAEB-t)] was examined to evaluate possible causes of enhanced susceptibility to infection and to gain information concerning the pathophysiology and prognosis. The following results were obtained : (1) The O(2)(－) production by neutrophils (O(2)(－) production) in 15 MDS patients was lower than that in healthy controls (3.75±2.93 vs 6.20±1.53 nmol/min/10(6) neutrophils, p<0.05). Three of the 15 MDS patients showed little O(2)(－) production. (2) There was inverse correlation between O(2)(－) production and the percentage of leukemic cells in the marrow in acute leukemia (r=0.55, p<0.01), but not in MDS. (3) The O(2)(－) production in 5 MDS patients showing morphological anomalies in a high percentage of neutrophils significantly lower than that in 10 MDS patients showing morphological anomalies in a low percentage of neutrophils (1.04±1.37 vs 5.15±2.50 nmol/min/10(6) neutrophils, p<0.05). (4) The O(2)(－) production in 5 patients with frequent fever (≧38℃) -episodes was significantly lower than that in 10 MDS patients with infrequent fever-episodes (2.22±2.15 vs 4.49±2.83 nmol/min 10(6) neutrophils, p<0.05). (5) Comparison of the O(2)(－) production between MDS patients with and without progression to overt leukemia showed no significant difference (4.25±3.26 vs 3.28±2.76 nmol/min/10(6) neutrophils). These findings suggest that impaired O(2)(－) production by neutrophils, probably due to the faulty differentiation from abnormal hematopoietic clones, is one possible cause of enhanced susceptibility to infection in MDS, and may provide clues for clinical management of infection, but is not useful for early detection of progression to overt leukemia. en-copyright= kn-copyright= en-aut-name=InagakiNoritoshi en-aut-sei=Inagaki en-aut-mei=Noritoshi kn-aut-name=稲垣登稔 kn-aut-sei=稲垣 kn-aut-mei=登稔 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=superoxide anion kn-keyword=superoxide anion en-keyword=myelodysplastic syndrome (MDS) kn-keyword=myelodysplastic syndrome (MDS) END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=3-4 article-no= start-page=211 end-page=221 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=1994 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Phagocytic function and production of colony-stimulating factor of peripheral mononuclear cells in the elderly kn-title=高齢者における貪食細胞機能並びに末梢単核球コロニー刺激因子産生能に検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Elderly individuals have an increased susceptibility to infections. To evaluate one of the possible causes of increased susceptibility to infections in the elderly, peripheral neutrophil and monocyte counts, neutrophil and monocyte chemiluminescence (ChL), macrophage precursor test and production of colony-stimulating factor (CSF) of peripheral mononuclear cells (PMNCs) were examined. The neutrophil and monocyte counts in the peripheral blood were not different between the elderly (≧70 years old) and the younger (<70years old) groups. In the neutrophil ChL assay, the base lines, peak levels and peak times were not different between the elderly and the younger groups. In the monocyte ChL assay, the peak level in the elderly group was significantly lower than that in the younger group (p<0.05). The values in a macrophage precursor test in the eldely group were signicantly lower than those in the younger group (P<0.05). CSF production of PMNCs in the eldely was significantly lower than that in the younger group(P<0.05). These findings indicated that the impaired intracel-lular bactericidal activity and maturation ability of monocytes and impaired CSF production of PMNCs were possible causes of increased susceptibility to infections in the elderly. en-copyright= kn-copyright= en-aut-name=OsadaKen en-aut-sei=Osada en-aut-mei=Ken kn-aut-name=長田建 kn-aut-sei=長田 kn-aut-mei=建 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=the elderly kn-keyword=the elderly en-keyword=mononuclear cells kn-keyword=mononuclear cells en-keyword=chemiluminescence kn-keyword=chemiluminescence en-keyword=macrophage precursor test kn-keyword=macrophage precursor test en-keyword=CSF production kn-keyword=CSF production END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=1-2 article-no= start-page=35 end-page=41 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Operative morbidity of elderly patients with gastrointestinal disease kn-title=高齢者消化器手術における術後合併症 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The operative morbidity and its relating factors were studied on 95 patients, 80 years old or older, operated for gastrointestinal (GI) diseases under general anesthesia at the department in a recent 11-year period. Among a total of 98 cases of GI diseases including 32 of gastric cancer, 17 of colorectal cancer, 16 of cholelithiasis and 33 of others, 108 procedures were performed for 38 gastric, 27 colorectal, 31 hepato-biliary-pancreatic and 12 other surgical conditions. Fifty-four operative complications occurred in 39 cases(41%), which were 13 respiratory, 11 delirium, 9 cardiovascular and 21 other complications. The respiratory morbidity rate was significantly high in males and significantly low in the cases receiving halanced epidural anesthesia. Postoperative delirium occurred more frequently in patients having an intraoperative blood loss of over 200 ml, and the cardiovascular morbidity rate was significantly high for an operative time of over 3 hours. The operative morbidity and 30-day operative mortality rate were significantly higher for emergency operations than for non-emergency operations. These findings suggest that, in the surgery for elderly patients and especially in an emergent situation, special care must be paid to decrease the quantity of bleeding and shorten the duration of operation by employing a proper procedure and anesthesia. en-copyright= kn-copyright= en-aut-name=ShiikiShigeo en-aut-sei=Shiiki en-aut-mei=Shigeo kn-aut-name=椎木滋雄 kn-aut-sei=椎木 kn-aut-mei=滋雄 aut-affil-num=1 ORCID= en-aut-name=NakagawaKazuhiro en-aut-sei=Nakagawa en-aut-mei=Kazuhiro kn-aut-name=中川和彦 kn-aut-sei=中川 kn-aut-mei=和彦 aut-affil-num=2 ORCID= en-aut-name=SasakiHiroshi en-aut-sei=Sasaki en-aut-mei=Hiroshi kn-aut-name=佐々木寛 kn-aut-sei=佐々木 kn-aut-mei=寛 aut-affil-num=3 ORCID= en-aut-name=YamashitaYutaka en-aut-sei=Yamashita en-aut-mei=Yutaka kn-aut-name=山下裕 kn-aut-sei=山下 kn-aut-mei=裕 aut-affil-num=4 ORCID= en-aut-name=YumuraMasahito en-aut-sei=Yumura en-aut-mei=Masahito kn-aut-name=湯村正仁 kn-aut-sei=湯村 kn-aut-mei=正仁 aut-affil-num=5 ORCID= en-aut-name=KodaniJohji en-aut-sei=Kodani en-aut-mei=Johji kn-aut-name=小谷穣治 kn-aut-sei=小谷 kn-aut-mei=穣治 aut-affil-num=6 ORCID= en-aut-name=YunokiYasuhiro en-aut-sei=Yunoki en-aut-mei=Yasuhiro kn-aut-name=柚木靖弘 kn-aut-sei=柚木 kn-aut-mei=靖弘 aut-affil-num=7 ORCID= en-aut-name=OritaKunzo en-aut-sei=Orita en-aut-mei=Kunzo kn-aut-name=折田薫三 kn-aut-sei=折田 kn-aut-mei=薫三 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=鳥取市立病院外科 affil-num=2 en-affil= kn-affil=鳥取市立病院外科 affil-num=3 en-affil= kn-affil=鳥取市立病院外科 affil-num=4 en-affil= kn-affil=鳥取市立病院外科 affil-num=5 en-affil= kn-affil=鳥取市立病院外科 affil-num=6 en-affil= kn-affil=鳥取市立病院外科 affil-num=7 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=高齢者 kn-keyword=高齢者 en-keyword=消化器手術 kn-keyword=消化器手術 en-keyword=術後合併症 kn-keyword=術後合併症 END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=7-8 article-no= start-page=751 end-page=758 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=199308 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Diagnostic studies of allergic gastroenteropathy Part 2. Diagnosis for allergic gastroenteropathy using phonoenterography analysis kn-title=アレルギー性胃腸症の診断に関する研究　第2編　腸音分析法を用いたアレルギー性胃腸症の診断に関する検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Oral challenge with specific allergens is generally used to diagnose allergic gastroenteropathy, but no evaluation criteria have yet been established. Therefore, we examined allergological tests (skin tests, IgE RAST score), oral challenge tests with causative allergens and oral administration tests using sorbitol as a nonspecific stimulator or distilled water as a control. Phonoenterograms were recorded intermittently for up to 5 hours after the tests and analyzed by a pulse density program. The results showed that it is possible to classify allergic gastroenteropathy into six subgroups by the allergological tests, symptoms and intestinal motility analyzed by phonoenterography. Increase of bowel sounds with or without positive allergological test and symptoms indicates a high suspicion of allergic gastroenteropathy. These data suggest that phonoenterography is useful in the diagnosis of this disease. It should also be possible to diagnose latent cases of allergic gastroenteropathy by non IgE-mediated allergic reactions. en-copyright= kn-copyright= en-aut-name=MiyashitaKatuhiro en-aut-sei=Miyashita en-aut-mei=Katuhiro kn-aut-name=宮下雄博 kn-aut-sei=宮下 kn-aut-mei=雄博 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=アレルギー性胃腸症 kn-keyword=アレルギー性胃腸症 en-keyword=腸音分析 kn-keyword=腸音分析 en-keyword=経口誘発試験 kn-keyword=経口誘発試験 en-keyword=ソルビトール kn-keyword=ソルビトール en-keyword=pulse density kn-keyword=pulse density END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=11-12 article-no= start-page=1125 end-page=1142 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Possible anti-tumor effects of drug-induced splenectomy with cyclophosphamide and indomethacin, and surgical splenectomy in combination with immunochemotherapy in tumor-bearing mice and gastric cancer patients kn-title=担癌マウスならびに胃癌患者における Cyclophosphamide と Indomethacin による薬物学的摘脾効果の可能性，および外科的摘脾と免疫化学療法併用に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Using tumor-bearing C(3)H/He mice, in which syngeneic MH-134 tumor cells were transplanted into the back subcutaneously, the possibility of drug-induced splenectomy using cyclophosphamide (CY) and indomethacin (INDO), the timing of chemo- and immuno-therapy, and the usefulness of the combination of surgical splenectomy with immunotherapy were investigated. In patients with gastric cancer, the significance of splenectomy and its combination with immunochemotherapy was also studied. The administration of CY in mice on day 3 after tumor transplantation in the initial stage of the tumor prolonged the survival time, while INDO under the same condition shortened it only when administered on day 3 after transplantation. The administration of an immunopotentiator, OK-432, prior to CY administration shortened the survival time, compared with that of single administration of CY, whereas the OK-432 administration on day 2 after the administration of CY prolonged the survival time. In the immunochemotherapy in which CY was administered on day 7 after transplantation of tumor and OK-432 was given every two days after additional 2 days, the anti-tumor effect of drug-induced splenectomy was not observed as judged from the tumor proliferating curve, but the splenectomy on day 3 after tumor transplantation, in the initial stage of the tumor, prolonged tne survival time. Similar results were observed, when INDO was used instead of CY. The concomitant splenectomy in the initial stage of gastric cancer resulted in a more effective prolongation of survival time. In the cases with adjuvant immunochemotherapy, preservation of the spleen in advanced cancer and splenectomy in the terminal stage of cancer were found to be preferable for effective prolongation of the survival time. en-copyright= kn-copyright= en-aut-name=YuiJiro en-aut-sei=Yui en-aut-mei=Jiro kn-aut-name=由井治郎 kn-aut-sei=由井 kn-aut-mei=治郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=薬物学的摘脾 kn-keyword=薬物学的摘脾 en-keyword=cyclophosphamide kn-keyword=cyclophosphamide en-keyword=indomethacin kn-keyword=indomethacin en-keyword=摘脾と免疫療法 kn-keyword=摘脾と免疫療法 en-keyword=摘脾と免疫化学療法 kn-keyword=摘脾と免疫化学療法 END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=1-2 article-no= start-page=145 end-page=162 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199402 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinicopatholgical studies on htpersensitivity pneumonitis : Cellular kinetics in bronchoalveolar lavage (BAL) fluid of the patients with hypersensitivity pneumonitis kn-title=過敏性肺臓炎の病態に関する研究ー気管支肺胞洗浄液中の細胞動態を中心にー en-subtitle= kn-subtitle= en-abstract= kn-abstract=The cellular components of bronchoalveolar lavage (BAL) fluids from 26 patients with hypersensitivity pneumonitis were analyzed with regard to the period of antigen exposure before BAL procedure. In the early phase of antigen exposure BAL fluids contained increased neutrophils as well as lymphocytes while a low percentage of neutrophils and a prominent increase of lymphocytes were observed in chronic antigen exposure. Furthermore, the in-creased neutrophils decreased rapidly after cessation of antigen exposure while lymphocytes decreased gradually. In the BAL fluids of patients with summer-type hypersensitivity pneumonitis, CD4+ percentages and CD4/CD8 rations were significantly decreased, but CD8+ percentages significantly increased during antigen exposure compared with that in healthy controls. However, the actual CD4+ cell counts in BAL fluids significantly increased while CD4+ percentage decreased. Thus, CD4+ as well as CD8+ may play important roles in the pathogenesis of hypersensitivity pneumonitis. Soluble IL-2 receptor (sIL-2R) levels in BAL fluids and serum obtained from patients with hypersensitivity pneumonitis, especially serum sIL-2R during the active phase, were signifi-cantly higher than those of normal controls, indicating that the elevated sIL-2R level reflect-ed a highly activated immune response. In relation to pulmonary fuction, the lympocyte percentage showed a significant inverse correlation with % TLC and PaCO2, while neutrophil percentage showed significant correlation with % TLC and inverse correlation with FEV 1.0%. These reaults suggest that neutrophilia in BAL fluids affects bronchobronchiolar disorders during the early phase, and lympocytosis in BAL fluids regulates organic changes of the lung in hypersensitivity pneumonitis. en-copyright= kn-copyright= en-aut-name=KajimotoKazuhiro en-aut-sei=Kajimoto en-aut-mei=Kazuhiro kn-aut-name=梶本和宏 kn-aut-sei=梶本 kn-aut-mei=和宏 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=過敏性肺臓炎 kn-keyword=過敏性肺臓炎 en-keyword=気管支肺胞洗浄法 kn-keyword=気管支肺胞洗浄法 en-keyword=Tリンパ球サブセット kn-keyword=Tリンパ球サブセット en-keyword=吸入誘発試験 kn-keyword=吸入誘発試験 en-keyword=肺機能 kn-keyword=肺機能 END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=7-8 article-no= start-page=883 end-page=892 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199408 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Xanthoma cells in sputa of patients with chronic obstructive lung diseases kn-title=慢性閉塞性肺疾患における喀痰中 Xanthoma cell に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Alveolar macrophages attack various foreign bodies inspired through the airway and destroy cell debris. Furthermore, a part of the surfactant produced by alveolar epithelium would be phagocytized by alveolar macrophages forming foamy cells in lung tissue. These formy cells could be detected by oil red O staining as xanthoma cells in sputa of patients with airway diseases. Therefore, xanthoma cells in sputa of patients with DPB, chronic bronchitis and bronchial asthma were evaluated to clarify the role in the pathogenesis of these respiratory diseases. All patients with DBP expectorated enormous amounts of xanthoma cells in sputa while 88% of the patients with chronic bronchitis and 41% of those with bronchial asthma had sputa containing xanthoma cells in a smaller number than DBP. Increased xanthoma cells were shown in DPB with longer disease duration, lower vital capacity, lower atrerial blood oxygen pressure, and pseudomonas infection. However, extreme obstruction of small airway diminished xanthoma cells in sputa. Xanthoma cells were shown in bronchial asthma especially in late onset and intractable asthmatics. These findings indicate that xanthoma cells in sputa reflect the existence of organic changes in the small airway which disturb the drainage of surfactant from alveolar area to bronchial trees. en-copyright= kn-copyright= en-aut-name=KawauchiKazuhisa en-aut-sei=Kawauchi en-aut-mei=Kazuhisa kn-aut-name=河内和久 kn-aut-sei=河内 kn-aut-mei=和久 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=びまん性汎細気管支炎 kn-keyword=びまん性汎細気管支炎 en-keyword=気管支喘息 kn-keyword=気管支喘息 en-keyword=喀痰 kn-keyword=喀痰 en-keyword=oil red O 染色 kn-keyword=oil red O 染色 en-keyword=xanthoma cell kn-keyword=xanthoma cell END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=7-8 article-no= start-page=751 end-page=756 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199408 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case report of esophageal cyst kn-title=食道囊腫の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Esophageal cyst is a relatively rare disease and about 91 cases have been reported in Japan. We report a new case of esophageal cyst. Tha patient was a 36-year-old male who complained of nausea and vomiting. We performed esophagography, endoscopy, endoxcopic echography, CT and MRI and found a cystic lesion in the lower esophagus. We made the diagnosis of an esophageal cyst and performed operation. The tumor was in the esophageal muscle but did not have a commissure to the esophageal lumen. We extirpated it with esophageal muscle and repaired the muscle defect with diaphragma. This tumor, 7.5×5.0cm in size, was a monolocular cyst and contained brown muddy material. Microscopic findings revealed a ciliated columnar epithelium and squamous epithelium in the cyst wall but cartilage was not found. The cyst was covered with double smooth muscle layers. It was difficult to differentiate an esophageal cyst from a paraesophageal bronchogenic cyst but these histological findings suggested that this cyst was an esophageal cyst. en-copyright= kn-copyright= en-aut-name=IshiiYasunori en-aut-sei=Ishii en-aut-mei=Yasunori kn-aut-name=石井泰則 kn-aut-sei=石井 kn-aut-mei=泰則 aut-affil-num=1 ORCID= en-aut-name=InoueFumiyuki en-aut-sei=Inoue en-aut-mei=Fumiyuki kn-aut-name=井上文之 kn-aut-sei=井上 kn-aut-mei=文之 aut-affil-num=2 ORCID= en-aut-name=BanHidetoshi en-aut-sei=Ban en-aut-mei=Hidetoshi kn-aut-name=伴秀利 kn-aut-sei=伴 kn-aut-mei=秀利 aut-affil-num=3 ORCID= en-aut-name=KamikawaYasuaki en-aut-sei=Kamikawa en-aut-mei=Yasuaki kn-aut-name=上川康明 kn-aut-sei=上川 kn-aut-mei=康明 aut-affil-num=4 ORCID= en-aut-name=OritaKunzo en-aut-sei=Orita en-aut-mei=Kunzo kn-aut-name=折田薫三 kn-aut-sei=折田 kn-aut-mei=薫三 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=食道囊腫 kn-keyword=食道囊腫 en-keyword=esophageal cyst kn-keyword=esophageal cyst en-keyword=気管支食道囊腫 kn-keyword=気管支食道囊腫 en-keyword=bronchial-esophageal cyst kn-keyword=bronchial-esophageal cyst en-keyword=foregut cyst kn-keyword=foregut cyst END start-ver=1.4 cd-journal=joma no-vol=111 cd-vols= no-issue=1-2 article-no= start-page=11 end-page=26 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Bacteriological and molecular epidemiological investigation on nosocomial infection caused by Methicillin-resistant Staphylococcus aureus and its pervention kn-title=MRSA 院内感染の細菌学的・分子疫学的調査と感染予防対策 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The colonization of methicillin-resistant Staphylococcus aureus (MRSA) was investigated in a private hospital three times for one year in an attempt to prevent the MRSA transmission. Total 22 MRSA strains were isolated. The pulse field gel electrophoresis (PFGE) was performed to investigate the route of transmission (infection way) in addition to characterize their bacteriological properties. Since the PFGE profiles were identical or very similar between the strain isolated from a patient and those from several nurses' hands and clothing cared for patient, the standard precautions including handwashing and gown technique have been performed. No transmission of MRSA through medical staff has been investigated in this hospital aftreward. Therefore, it was confirmed that the epidemiological investigation and its educational direction contribute to prevent the nosocomical infection of MRSA. en-copyright= kn-copyright= en-aut-name=SendaYoshiko en-aut-sei=Senda en-aut-mei=Yoshiko kn-aut-name=千田好子 kn-aut-sei=千田 kn-aut-mei=好子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部細菌学講座 en-keyword=MRSA kn-keyword=MRSA en-keyword=院内感染対策 kn-keyword=院内感染対策 en-keyword=PFGE法 kn-keyword=PFGE法 END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=3-6 article-no= start-page=83 end-page=95 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960629 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Comparison of postoperative circulatory, respiratory and immunological parameters between one-stage and two-stage surgery of intrathoracic esophageal carcinoma kn-title=循環，呼吸，免疫動態よりみた胸部食道癌に対する1期的手術と分割手術との比較検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=There are two major surgical procedures for excision of esophageal carcinoma and reconstruction of the esophagus: the one-stage procedure and the two-stage procedure. In the present study, we evaluated the two methods by comparing the cardiovascular, respiratory and immune parameters of 10 patients who underwent one-stage procedure with those of 10 other patients who underwent two-stage procedure. To estimate cardiovascular function, we measured the left ventricular stroke work index (LVSWI)-pulmonary capillary wedge pressure (PCWP). Most of the patients treated by the one-stage procedure showed a significant decrease in LVSWI-PCWP, whereas the index of patients treated by the two-stage procedure did not change much. When we assessed the respiratory system by forced vital capacity (FVC) and peak expiratory flow (PEF), the patients treated by the two-stage procedure recovered much faster and better than those receiving the one-stage procedure. Natural killer (NK) activity in lymphocytes was also measured as a marker of the immuno-reactive system. Although most patients show a drop in NK activity one week after major surgery, NK activity did not demonstrate a significant change in any of the patients who underwent the two-stage procedume. Thus, our systemic comparison of the three different parameters demonstrated better results after the two-stage procedure and we recommend it over the one-stage procedure, especially for aged and high risk patients. en-copyright= kn-copyright= en-aut-name=MuramatsuTomoyoshi en-aut-sei=Muramatsu en-aut-mei=Tomoyoshi kn-aut-name=村松友義 kn-aut-sei=村松 kn-aut-mei=友義 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=intrathoracic esophageal carcinoma kn-keyword=intrathoracic esophageal carcinoma en-keyword=one-stage procedure kn-keyword=one-stage procedure en-keyword=two-stage procedure kn-keyword=two-stage procedure en-keyword=reduction of operative stress kn-keyword=reduction of operative stress END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=3-6 article-no= start-page=71 end-page=82 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960629 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Prevention of peritoneal dissemination and serosal invasion of digestive tract cancer in an experimental murine model kn-title=癌漿膜浸潤および腹膜播種の防止に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We report a novel prophylactic strategy for peritoneal dissemination and serosal invasion of digestive tract cancer in a murine model, in which the murine abdominal wall was compared to the wall of the human digestive tract. Subcutaneous injection of MH-134 cells to the abdominal wall of C3H mice induced tumors on the parietal peritoneum, and eventually caused peritoneal dissemination with time. In this model, the intraperitoneal administration of OK-432, a type of biological response modifier, after tumor implantation significantly inhibited the development of peritoneal dissemination of tumor cells. This effect was more profound in mice with tumors that extended to the peritoneal surface (designated as S1 stage). Histological examination revealed both the remarkable necrosis of tumoral tissue and the formation of a collagen fiber at the edge of the tumor. This antitumoral effect of OK-432 is thought to be mediated by both macrophages and lymphocytes migrated into the peritoneal cavity, because the administration of Carrageenan and anti-lymphocyte serum completely blocked the antitumoral effect of OK-432. en-copyright= kn-copyright= en-aut-name=IijimaTakashi en-aut-sei=Iijima en-aut-mei=Takashi kn-aut-name=飯島崇史 kn-aut-sei=飯島 kn-aut-mei=崇史 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=漿膜浸潤 kn-keyword=漿膜浸潤 en-keyword=腹膜播種性転移 kn-keyword=腹膜播種性転移 en-keyword=OK-432 kn-keyword=OK-432 en-keyword=細胞性間質反応 kn-keyword=細胞性間質反応 en-keyword=線維性間質反応 kn-keyword=線維性間質反応 END start-ver=1.4 cd-journal=joma no-vol=109 cd-vols= no-issue=3-6 article-no= start-page=57 end-page=74 dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=19970630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A study of the living environment and activities of daily living in centenarians kn-title=長寿者の居住地の特性と日常生活動作能力 (Activities of Daily Living : ADL) en-subtitle= kn-subtitle= en-abstract= kn-abstract=A study on relationship between the living environment and activities of daily living (ADL) was conducted to all eldery persons of more than 100 years old in 1993. The response was received from 840 males (73.6%) of 100-107 years of ages. Living environment was devided into three areas according to the geographical areas (Hokkaido-Tohoku-Hokuriku-Sanin, Kanto-Tokai-Kinki, and Sanyo-Shikoku-Kyushu), two community types according to an urban or an agricultural or fishing village, and four community sizes according to number of the population. Factors considered to contribute to a high level of ADL were evaluated. The results can be summarized as follows. 1. According to the geographical area, the independence rate (percentage of individuals who were competent for ADL) was significantly higher in Sanyo-Shikoku-Kyushu area than in Kanto-Tokai-Kinki area in all items examined (transferring, feeding, continence and bathing). Regional differences were observed in the state of living, state of medical care, social and cultural activities, and dietary habit since the age of 80 years, watching TV and an interest in health as social and cultural activites were related to high independence rates in areas such as Sanyo. 2. According to the community type, the state of medical care, whether there was a family doctor, social and cultural activities, and dietary habit since tha age of 80 years in agricultural and fishing communities appeared to be favorable for independence rate, but there were not observed significant relations. 3. According to the community size, none of the residents in large cities were independent in eating, continence, or bathing. The independence rate of continence was significantly lower than that in small cities and towns or villages in rural districts, suggesting that large cities are an environment unfavorable for socially independent longevity. The household composition, social and cultural activities, and dietary habit since the age of 80 years were different according to the community size, and reading newspapers of social and cultural activities was related to high independence rates in small cities and towns or villages of rural districts. en-copyright= kn-copyright= en-aut-name=ArakiHidetoshi en-aut-sei=Araki en-aut-mei=Hidetoshi kn-aut-name=荒木英俊 kn-aut-sei=荒木 kn-aut-mei=英俊 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学講座 en-keyword=長寿者 kn-keyword=長寿者 en-keyword=日常生活動作能力 kn-keyword=日常生活動作能力 en-keyword=居住地の特性 kn-keyword=居住地の特性 END start-ver=1.4 cd-journal=joma no-vol=111 cd-vols= no-issue=3-8 article-no= start-page=51 end-page=60 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Characteristics of elderly patients who stopped receiving day service at a welfare facility kn-title=デイサービス中断の要因 ―女性の場合― en-subtitle= kn-subtitle= en-abstract= kn-abstract=To cope with problems resulting from a rapidly aging society with a low birth rate, effective methods must be established to support home care services through a welfare service system. Characteristics of 40 elderly women living in S City with their familes who had stopped receiving "day service" (discontinued group) were compared with 40 age-matched elderly women selected among those regularly receiving the day service st the same facility. In addition, factors that influenced the women to stop receiving "day service" were studied. A questionnaire consisting of 20 items concerning various activies of daily living (ADL), instrumental ADL(IADL), health states, ecnomical coditions, and reasons for quiting the service was completed by all subjects. The results showed that ADL, IADL and health staes were significantly lower in the discontinued group than those of the control group. About half of the elderly in the dis-continued group quit the services in order to receive medical care at medical institutes. These women were older in age and lower ADL and IADl than those who quit for other reasons. Time needed to care for their husbands and housekeeping, were also reasons for qutiting the day service in the relatively younger group whose ADL snd IADL were well maintitained. Therefore, I concluded that "day service at welfare facilities" may become competitive with medical and health facilities already supporting home care services for the aged. if knowledge increases about social resources to support home care services. en-copyright= kn-copyright= en-aut-name=OkanoHatsue en-aut-sei=Okano en-aut-mei=Hatsue kn-aut-name=岡野初枝 kn-aut-sei=岡野 kn-aut-mei=初枝 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科 en-keyword=Elderly kn-keyword=Elderly en-keyword=Day Service kn-keyword=Day Service en-keyword=ADL kn-keyword=ADL en-keyword=IADL kn-keyword=IADL en-keyword=Stop receiving services kn-keyword=Stop receiving services END start-ver=1.4 cd-journal=joma no-vol=114 cd-vols= no-issue=3 article-no= start-page=289 end-page=296 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=20030131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effect of phospholipase A(2) on proliferation of the primary cultured biliary epithelial cells from the extra-hepatic bile duct to rats using D-valine containing medium kn-title=D-バリン培地法により選択的に初代培養したラット胆管上皮細胞に対する Phospholipase A(2) の細胞増殖促進効果の解析 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We hypothesized that a high level of phospholipase A(2) (PLA(2)) in bile juice works as a growth factor of biliary epithelial cells and causes hyperplastic change of the bile duct in pancreaticobiliary maljunction. in order to examine this hypothesis, we established a primary culture system of biliary epithelial cells from the extra-hepatic bile duct of rats. We successfully excluded fibroblasts from the epithelial cells using D-valine-containing medium and the single-cell cloning method. The established cells exhibited the characteristic features of rat bile duct epithelial cells. They were stained with anti-cytokeratin antibody, a marker protein of epithelial cells, were positive with PAS stain, and possessed the architectures of microvilli, tonofilament fibers and desmosomes. The effect of PLA(2) on proliferation of these cells was then examined. We clearly demonstrated that PLA(2) at nano-molar concentration (50nM, 100nM), that is, equivalent to the level of PLA(2) in the bile juice of pancreaticobiliary maljunction cases, caused a significant enhancement of epithelial cell proliferation. en-copyright= kn-copyright= en-aut-name=OguraKaoru en-aut-sei=Ogura en-aut-mei=Kaoru kn-aut-name=小倉薫 kn-aut-sei=小倉 kn-aut-mei=薫 aut-affil-num=1 ORCID= en-aut-name=WatanabeYasuhiro en-aut-sei=Watanabe en-aut-mei=Yasuhiro kn-aut-name=渡辺泰宏 kn-aut-sei=渡辺 kn-aut-mei=泰宏 aut-affil-num=2 ORCID= en-aut-name=HiramineChiharu en-aut-sei=Hiramine en-aut-mei=Chiharu kn-aut-name=平峯千春 kn-aut-sei=平峯 kn-aut-mei=千春 aut-affil-num=3 ORCID= en-aut-name=NakagawaToshitaka en-aut-sei=Nakagawa en-aut-mei=Toshitaka kn-aut-name=中川利孝 kn-aut-sei=中川 kn-aut-mei=利孝 aut-affil-num=4 ORCID= en-aut-name=TokiAkira en-aut-sei=Toki en-aut-mei=Akira kn-aut-name=土岐彰 kn-aut-sei=土岐 kn-aut-mei=彰 aut-affil-num=5 ORCID= en-aut-name=TokudaMasaaki en-aut-sei=Tokuda en-aut-mei=Masaaki kn-aut-name=徳田雅明 kn-aut-sei=徳田 kn-aut-mei=雅明 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=香川医科大学小児外科学 affil-num=2 en-affil= kn-affil=香川医科大学小児外科学 affil-num=3 en-affil= kn-affil=香川医科大学基礎看護学 affil-num=4 en-affil= kn-affil=香川医科大学附属実験実習機器センター affil-num=5 en-affil= kn-affil=香川医科大学小児外科学 affil-num=6 en-affil= kn-affil=香川医科大学生理学 en-keyword=膵・胆管合流異常 kn-keyword=膵・胆管合流異常 en-keyword=胆管上皮細胞 kn-keyword=胆管上皮細胞 en-keyword=D－バリン kn-keyword=D－バリン en-keyword=Phospholipase A(2) kn-keyword=Phospholipase A(2) en-keyword=細胞増殖 kn-keyword=細胞増殖 END start-ver=1.4 cd-journal=joma no-vol=115 cd-vols= no-issue=2 article-no= start-page=145 end-page=150 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=神経内視鏡を用いた脳神経外科手術 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=松井利浩 kn-aut-sei=松井 kn-aut-mei=利浩 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=伊達勲 kn-aut-sei=伊達 kn-aut-mei=勲 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院　医歯学総合研究科　神経病態外科学 affil-num=2 en-affil= kn-affil=岡山大学大学院　医歯学総合研究科　神経病態外科学 en-keyword=neuroendoscope kn-keyword=neuroendoscope en-keyword=neurosurgery kn-keyword=neurosurgery en-keyword=hydrocephalus kn-keyword=hydrocephalus en-keyword=third ventriculostomy kn-keyword=third ventriculostomy en-keyword=biopsy kn-keyword=biopsy END start-ver=1.4 cd-journal=joma no-vol=116 cd-vols= no-issue=2 article-no= start-page=97 end-page=101 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=動脈硬化発生に関わる血管内皮細胞のナノ／マイクロメカニクス解析―岡山大学医学賞 （砂田賞） を受賞して― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=片岡則之 kn-aut-sei=片岡 kn-aut-mei=則之 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=橋本謙 kn-aut-sei=橋本 kn-aut-mei=謙 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=梶谷文彦 kn-aut-sei=梶谷 kn-aut-mei=文彦 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院歯学総合研究科　システム循環生理学 affil-num=2 en-affil= kn-affil=岡山大学大学院歯学総合研究科　システム循環生理学 affil-num=3 en-affil= kn-affil=岡山大学大学院歯学総合研究科　システム循環生理学 en-keyword=動脈硬化 kn-keyword=動脈硬化 en-keyword=血管内皮細胞 kn-keyword=血管内皮細胞 en-keyword=単球 kn-keyword=単球 en-keyword=ナノ／マイクロメカニクス kn-keyword=ナノ／マイクロメカニクス END start-ver=1.4 cd-journal=joma no-vol=116 cd-vols= no-issue=3 article-no= start-page=273 end-page=279 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=泌尿器科における難治性感染症「尿路バイオフィルム感染症」 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=門田晃一 kn-aut-sei=門田 kn-aut-mei=晃一 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=公文裕巳 kn-aut-sei=公文 kn-aut-mei=裕巳 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯学総合研究所　泌尿器病態学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯学総合研究所　泌尿器病態学 en-keyword=尿路感染症 kn-keyword=尿路感染症 en-keyword=細菌バイオフィルム kn-keyword=細菌バイオフィルム en-keyword=院内感染 kn-keyword=院内感染 END start-ver=1.4 cd-journal=joma no-vol=116 cd-vols= no-issue=3 article-no= start-page=261 end-page=271 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=②医療の制度経営論／持続可能性の観点から診る医療保険制度改革 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=西田在賢 kn-aut-sei=西田 kn-aut-mei=在賢 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=武蔵野大学大学院 en-keyword=医療保険 kn-keyword=医療保険 en-keyword=国民医療費 kn-keyword=国民医療費 en-keyword=総保健医療支出 kn-keyword=総保健医療支出 en-keyword=経営持続性 kn-keyword=経営持続性 en-keyword=疾病別医療資金管理 kn-keyword=疾病別医療資金管理 END start-ver=1.4 cd-journal=joma no-vol=116 cd-vols= no-issue=3 article-no= start-page=235 end-page=244 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ペルオキシソームの機能とペルオキシソーム病 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=石川哲也 kn-aut-sei=石川 kn-aut-mei=哲也 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=田中ゆき kn-aut-sei=田中 kn-aut-mei=ゆき aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科　検査技術科学専攻機能解折学講座 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科　検査技術科学専攻機能解折学講座 en-keyword=細胞内小器官 kn-keyword=細胞内小器官 en-keyword=ペルオキシソーム kn-keyword=ペルオキシソーム en-keyword=ペルオキシソーム病 kn-keyword=ペルオキシソーム病 en-keyword=酸化酵素 kn-keyword=酸化酵素 END start-ver=1.4 cd-journal=joma no-vol=117 cd-vols= no-issue=2 article-no= start-page=127 end-page=133 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050901 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Two cases of adult onset Schonlein-Henoch purpura with gastrointestinal manifestations kn-title=Schönlein-Henoch 紫斑病による腹痛症を呈し，内視鏡所見を観察しえた成人男性の２例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We describe two cases of adult-onset Schonlein-Henoch purpura with gastrointestinal manifestations. Case 1: A 73-year-old man was admitted to our hospital because of abdominal pain, diarrhea and fever. On physical examination, the abdomen was normal, and there were many palpable petechial hemorrhages on the lower extremities.Skin biopsy revealed infiltrations of lymphocytes, neutrophils and eosinophils into the dermis. A computed tomographic (CT) scan of the abdomen disclosed thickening of the intestinal wall in the duodenum and jejunum.Upper gastrointestinal fiberscopy revealed petechiation on the stomach and erosions on the duodenum. Case 2: A 54-year-old man was admitted to our hospital because of hematochezia.The patient had pharyngitis 4 days before admission, and his serum anti-streptolysion O level was increased.On physical examination, there were faint purpuras on the lower extremities.Skin biopsy revealed a histological image of leukocytoclastic vasculitis. A CT scan of the abdomen disclosed thickening of the intestinal wall in the duodenum, jejunum and ileum.Gastrointestinal fiberscopy revealed petechiation on the stomach and ulceration on the cecum. en-copyright= kn-copyright= en-aut-name=IwamuroMasaya en-aut-sei=Iwamuro en-aut-mei=Masaya kn-aut-name=岩室雅也 kn-aut-sei=岩室 kn-aut-mei=雅也 aut-affil-num=1 ORCID= en-aut-name=OhyaShogen en-aut-sei=Ohya en-aut-mei=Shogen kn-aut-name=大家昌源 kn-aut-sei=大家 kn-aut-mei=昌源 aut-affil-num=2 ORCID= en-aut-name=YoshiokaMasao en-aut-sei=Yoshioka en-aut-mei=Masao kn-aut-name=吉岡正雄 kn-aut-sei=吉岡 kn-aut-mei=正雄 aut-affil-num=3 ORCID= en-aut-name=NasuTatsuyo en-aut-sei=Nasu en-aut-mei=Tatsuyo kn-aut-name=那須達世 kn-aut-sei=那須 kn-aut-mei=達世 aut-affil-num=4 ORCID= en-aut-name=OgawaTsuneyoshi en-aut-sei=Ogawa en-aut-mei=Tsuneyoshi kn-aut-name=小川恒由 kn-aut-sei=小川 kn-aut-mei=恒由 aut-affil-num=5 ORCID= en-aut-name=ItoMamoru en-aut-sei=Ito en-aut-mei=Mamoru kn-aut-name=伊藤守 kn-aut-sei=伊藤 kn-aut-mei=守 aut-affil-num=6 ORCID= en-aut-name=IshiyamaShuhei en-aut-sei=Ishiyama en-aut-mei=Shuhei kn-aut-name=石山修平 kn-aut-sei=石山 kn-aut-mei=修平 aut-affil-num=7 ORCID= en-aut-name=FujiwaraAkiko en-aut-sei=Fujiwara en-aut-mei=Akiko kn-aut-name=藤原明子 kn-aut-sei=藤原 kn-aut-mei=明子 aut-affil-num=8 ORCID= en-aut-name=ShiodeJunji en-aut-sei=Shiode en-aut-mei=Junji kn-aut-name=塩出純二 kn-aut-sei=塩出 kn-aut-mei=純二 aut-affil-num=9 ORCID= en-aut-name=YamamotoKazuhide en-aut-sei=Yamamoto en-aut-mei=Kazuhide kn-aut-name=山本和秀 kn-aut-sei=山本 kn-aut-mei=和秀 aut-affil-num=10 ORCID= en-aut-name=ItoshimaTatsuya en-aut-sei=Itoshima en-aut-mei=Tatsuya kn-aut-name=糸島達也 kn-aut-sei=糸島 kn-aut-mei=達也 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=2 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=3 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=4 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=5 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=6 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=7 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=8 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=9 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=10 en-affil= kn-affil=岡山済生会総合病院内科 affil-num=11 en-affil= kn-affil=岡山済生会総合病院内科 en-keyword=Schonlein-Henoch 紫斑病 (Schonlein-Henoch purpura) kn-keyword=Schonlein-Henoch 紫斑病 (Schonlein-Henoch purpura) en-keyword=アレルギー性紫斑病 (allergic purpura) kn-keyword=アレルギー性紫斑病 (allergic purpura) en-keyword=消化管内視鏡検査 (gastrointestinal fiberscopy) kn-keyword=消化管内視鏡検査 (gastrointestinal fiberscopy) en-keyword=成人 (adult-onset) kn-keyword=成人 (adult-onset) END start-ver=1.4 cd-journal=joma no-vol=118 cd-vols= no-issue=3 article-no= start-page=215 end-page=220 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=内臓脂肪組織に由来するセリンプロテアーゼ阻害剤：Vaspin の同定肥満状態でインスリン感受性を高める新規アディポサイトカイン en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=肥田和之 kn-aut-sei=肥田 kn-aut-mei=和之 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=和田淳 kn-aut-sei=和田 kn-aut-mei=淳 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=江口潤 kn-aut-sei=江口 kn-aut-mei=潤 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=ZhangHong kn-aut-sei=Zhang kn-aut-mei=Hong aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=馬場雅子 kn-aut-sei=馬場 kn-aut-mei=雅子 aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=清田綾 kn-aut-sei=清田 kn-aut-mei=綾 aut-affil-num=6 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=橋本泉 kn-aut-sei=橋本 kn-aut-mei=泉 aut-affil-num=7 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=岡田達夫 kn-aut-sei=岡田 kn-aut-mei=達夫 aut-affil-num=8 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=安原章浩 kn-aut-sei=安原 kn-aut-mei=章浩 aut-affil-num=9 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=中司敦子 kn-aut-sei=中司 kn-aut-mei=敦子 aut-affil-num=10 ORCID= en-aut-name= en-aut-sei= 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