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タイトル(別表記) Adenocarcinoma in the jejunum 20 years after surgery for familial adenomatous polyposis
フルテキストURL 129_111.pdf
著者 杉原 雄策| 川野 誠司| 原田 馨太| 高嶋 志保| 竹井 大介| 井口 俊博| 高原 政宏| 平岡 佐規子| 母里 淑子| 岸本 浩行| 永坂 岳司| 岡田 裕之|
抄録 A 58-year-old Japanese man visited a local clinic for the evaluation of a stomachache. He was diagnosed with intestinal obstruction. His medical history included a proctocolectomy at the age of 38 years, due to familial adenomatous polyposis (FAP). He was referred to our institution, where he underwent a computed tomography examination and endoscopy of the small intestine. The pathological diagnosis was adenocarcinoma. No invasive or metastatic lesions were observed. Therefore, partial resection of the ileum with lymphadenectomy and reconstruction of the ileostomy were performed. Pathological examination revealed that the tumor was type 2, pT3 (SS) , pN1, pPM0, pDM0, pRM0, INFb, ly1, v1, pEX0, PN0. Twenty-nine days after the surgery, the patient was diagnosed with lung metastasis and he underwent lung radiofrequency ablation. We suggest that long-term follow-up is necessary for patients after surgery for FAP, because of the risk of malignant disease developing in other organs.
キーワード 家族性大腸腺腫症 (familial adenomatous polyposis) 小腸癌 (jejunal cancer) 小腸内視鏡検査 (small intestine endoscope)
出版物タイトル 岡山医学会雑誌
発行日 2017-08-01
巻 129巻
号 2号
開始ページ 111
終了ページ 114
ISSN 0030-1558
関連URL https://doi.org/10.4044/joma.129.111
言語 日本語
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.111
NAID 130006039373
タイトル(別表記) Retroperitoneal abscess that ruptured the aorta: Invasive Klebsiella pneumoniae syndrome
フルテキストURL 129_107.pdf
著者 山崎 賢士| 榊間 昌哲| 長倉 優花| 橋本 紘幸| 田代 傑| 三輪 真史| 米村 克彦|
抄録 An 80-year-old Japanese man was admitted to our hospital in April 2016 with an acute high-grade fever and back pain. A systemic contrast-enhanced computed tomography scan disclosed a retroperitoneal abscess around his aorta. The blood culture revealed Klebsiella pneumoniae. Antibiotics (Cefotaxime 1 g i.v. q 6 hours) were administered, but the patient's symptoms worsened. The abscess then ruptured the aorta. An emergency surgical repair was done, and the patient recovered. Invasive Klebsiella pneumoniae syndrome has been detected in southeast Asia over the past two decades, and here we describe a rare case of a retroperitoneal abscess caused by Klebsiella pneumoniae that ruptured the aorta.
キーワード invasive Klebsiella pneumoniae syndrome 腹部大動脈破裂 (ruptured abdominal aorta) 後腹膜膿瘍 (retroperitoneal abscess)
出版物タイトル 岡山医学会雑誌
発行日 2017-08-01
巻 129巻
号 2号
開始ページ 107
終了ページ 109
ISSN 0030-1558
関連URL https://doi.org/10.4044/joma.129.107
言語 日本語
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.107
NAID 130006039375
タイトル(別表記) The development of a scale to measure stress recognition during the treatment of diabetes patients
フルテキストURL 129_93.pdf
著者 住吉 和子| 川田 智恵子| 岡本 辰夫| 大橋 睦子| 實金 栄| 高林 範子| 太湯 好子| 金 外淑| 和田 淳| 四方 賢一| 中嶋 和夫|
抄録  The purpose of this study was to establish a measurement scale for "stress recognition in receiving treatment" in patients with diabetes. A self-completed questionnaire was distributed to 149 type-2 diabetes outpatients in March-May 2015 after authorization from Okayama Prefectural University and the ethics committee of the hospital.  The "stress recognition in receiving treatment" scale was designed as a second-order factor model consisting of 14 items and the following four factors : the respondent's sense of (1) the burden of being sick, (2) the burden on interpersonal relationships, (3) the burden of treatment, and (4) the burden of medical expenses.  Stress recognition in treatment means recognition of being stressed in the burdens related to the illness, interpersonal relationships, treatment and medical expenses.  The suitability of the questionnaire data was then evaluated with a structural equation model. The suitability of the factor model to the data satisfied the statistically acceptable standards as Comparative Fit Index (CFI) =0.931, Root Mean Square Error of Approximation (RMSEA) =0.096, Tucker-Lewis Index (TLI) =0.946.  As the construct validity was not examined by the scale created in this study or by existing scale, it was verified by using the degrees of mental healthiness and HbA1c that were proved to be associated with the sense of burden.  In addition, the construct validity of the questionnaire was supported by a significant correlation between the Japanese version of the WHO-Five Well-being Index (S-WHO-5-J) and the patients' HbA1c levels. The use of this measure is expected to contribute to the early detection of a decline in a diabetic patient's activities of daily living and to the early confirmation of patients' support status.
キーワード 糖尿病患者 (diabetes patients) 治療 (treatment) ストレス認知 (stress recognition) 尺度開発 (development of a scale)
出版物タイトル 岡山医学会雑誌
発行日 2017-08-01
巻 129巻
号 2号
開始ページ 93
終了ページ 99
ISSN 0030-1558
関連URL https://doi.org/10.4044/joma.129.93
言語 日本語
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.93
NAID 130006039367
フルテキストURL K0005280_fulltext.pdf
著者 Ishigami, Shuta| Ohtsuki, Shinichi| Tarui, Suguru| Ousaka, Daiki| Eitoku, Takahiro| Kondo, Maiko| Okuyama, Michihiro| Kobayashi, Junko| Baba, Kenji| Arai, Sadahiko| Kawabata, Takuya| Yoshizumi, Ko| Tateishi, Atsushi| Kuroko, Yosuke| Iwasaki, Tatsuo| Sato, Shuhei| Kasahara, Shingo| Sano, Shunji| Oh, Hidemasa|
キーワード cell therapy congenital heart disease hypoplastic left heart syndrome stem cells
備考 学位審査副論文|
発行日 2015-02
出版物タイトル Circulation Research
巻 116巻
号 4号
出版者 Lippincott Williams & Wilkins
開始ページ 653
終了ページ 664
ISSN 00097330
NCID AA00133553
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 25403163
DOI 10.1161/circresaha.116.304671
Web of Science KeyUT 000349804900015
関連URL https://doi.org/10.1161/CIRCRESAHA.116.304671 http://ousar.lib.okayama-u.ac.jp/54044 http://ousar.lib.okayama-u.ac.jp/54263
フルテキストURL K0005439_other1.pdf
著者 Onoda, Satoshi| Kimata, Yoshihiro| Yamada, Kiyoshi| Seki, Noriko| Hiramatsu, Yuji|
キーワード gynecologic cancer lower limb lymphedema risk factor secondary lymphedema superficial groin lymph nodes
備考 学位審査副論文|
発行日 2016-12
出版物タイトル journal of Surgical Oncology
巻 114巻
号 8号
出版者 Wiley-Liss
開始ページ 940
終了ページ 946
ISSN 00224790
NCID AA00708010
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 27709601
DOI 10.1002/jso.24463
Web of Science KeyUT 000392939700007
関連URL https://doi.org/10.1002/jso.24463
フルテキストURL K0005578_abstract_review.pdf K0005578_summary.pdf K0005578_fulltext.pdf
著者 渡邉 典行|
発行日 2017-06-30
資料タイプ 学位論文
学位授与番号 甲第5578号
学位授与年月日 2017-06-30
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
フルテキストURL K0005574_abstract_review.pdf K0005574_summary.pdf
著者 更科 俊洋|
発行日 2017-06-30
資料タイプ 学位論文
学位授与番号 甲第5574号
学位授与年月日 2017-06-30
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
フルテキストURL K0005440_other1.pdf
著者 Hiroshi, Umemura| Yamasaki, Osamu| Kaji, Tatsuya| Otsuka, Masaki| Asagoe, Kenji| Takata, Minoru| Iwatsuki, Keiji|
キーワード 5-S-cysteinyl-dopa biomarker lactate dehydrogenase malignant melanoma serum 5-S-CD
備考 学位審査副論文|
発行日 2017-04
出版物タイトル Journal of Dermatology
巻 44巻
号 4号
出版者 Wiley-Blackwell
開始ページ 449
終了ページ 454
ISSN 03852407
NCID AA00696658
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 27786364
DOI 10.1111/1346-8138.13651
Web of Science KeyUT 000398690600029
関連URL isVersionOf https://doi.org/10.1111/1346-8138.13651
フルテキストURL K0005463_other1.pdf
著者 Higuchi, Yuji | Uchitomi, Yosuke| Fujimori, Maiko| Koyama, Toshihiro| Kataoka, Hitomi| Kitamura, Yoshihisa| Sendo, Toshiaki| Inagaki, Masatoshi|
キーワード Empathy Hospital pharmacist Japan Pharmaceutical care
備考 The final publication is available at Springer| 岡山大学審査学位副論文|
発行日 2015-12
出版物タイトル International Journal of Clinical Pharmacy
巻 37巻
号 6号
出版者 Springer
開始ページ 1258
終了ページ 1266
ISSN 2210-7703
NCID AA12633112
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 26441314
DOI 10.1007/s11096-015-0204-2
Web of Science KeyUT 000363490100042
関連URL https://doi.org/10.1007/s11096-015-0204-2 http://ousar.lib.okayama-u.ac.jp/55016
JaLCDOI 10.18926/AMO/55207
フルテキストURL 71_3_241.pdf
著者 Iwamuro, Masaya| Tanaka, Shouichi| Moritou, Yuki| Inaba, Tomoki| Higashi, Reiji| Kusumoto, Chiaki| Yunoki, Naoko| Ishikawa, Shin| Okamoto, Yuko| Kawai, Yoshinari| Kitada, Ken-ichi| Takenaka, Ryuta| Toyokawa, Tatsuya| Okada, Hiroyuki|
抄録  Most gastric bezoars can be treated with endoscopic fragmentation combined with or without cola dissolution, whereas laparotomy or laparoscopic surgery is generally inevitable for small intestinal bezoars because they cause small bowel obstruction. Therefore, early diagnosis and management of gastric bezoars are necessary to prevent bezoar-induced ileus. To investigate the incidence of overlooked gastric bezoars during the initial esophagogastroduodenoscopy, we retrospectively reviewed the cases of 27 patients diagnosed with gastrointestinal bezoars. The bezoars were diagnosed using esophagogastroduodenoscopy (n=25), abdominal ultrasonography (n=1), and barium follow-through examination (n=1). Bezoars were overlooked in 9/25 patients (36.0%) during the initial endoscopy examination because the bezoars were covered with debris in the stomach. Of the 9 patients, 8 had concomitant gastric ulcers, and the other patient had gastric lymphoma. Although a computed tomography (CT) scan was performed before the second-look endoscopy in 8 of the 9 patients, the bezoars were mistaken as food debris on CT findings and were overlooked in these patients. In conclusion, gastric bezoars may not be discovered during the initial esophagogastroduodenoscopy and CT scan. In cases with debris in the stomach, second-look endoscopy is essential to detect bezoars.
キーワード bezoar gastric ulcer foreign bodies phytobezoar
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-06
巻 71巻
号 3号
出版者 Okayama University Medical School
開始ページ 241
終了ページ 247
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28655944
JaLCDOI 10.18926/AMO/55205
フルテキストURL 71_3_227.pdf
著者 Sasaki, Katsumi| Wada, Koichiro| Araki, Motoo| Kobayashi, Yasuyuki| Sugimoto, Morito| Ebara, Shin| Watanabe, Toyohiko| Nasu, Yasutomo|
抄録  We elucidate the fate of cases clinically suspected of carcinoma in situ (Cis) of the upper tract with serial ureteroscopy. Of 143 patients who underwent ureteroscopy for suspected upper tract urothelial carcinoma (UTUC) between January 2008 and February 2016, 12 cases with consistently positive urine cytology and poorly detectable upper-tract malignancies by imaging were reviewed. In these 12 patients, 19 ureteroscopy procedures (25 renal units) were performed. Vesical random biopsy was performed before the 1st ureteroscopy to exclude malignancy of the bladder in all 12 cases. Median follow-up was 42 (13-67) months. Positive biopsy results at the 1st ureteroscopy were obtained in 3 (25%) patients and all were diagnosed wth Cis of the upper tract. Two (17%) of 9 patients who were negative or inconclusive at the 1st ureteroscopy were finally diagnosed as UTUC, but plural ureteroscopy procedures were needed for the diagnoses in both. Carcinoma of the bladder appeared in 5 (42%) patients during follow-up, despite the earlier ruling out of vesical malignancy. Four (33%) of those 5 patients never developed upper-tract urothelial carcinoma during follow-up. Caution is required before undertaking radical surgery for cases clinically suspected of Cis of the upper tract. In our experience, only 42% of such patients developed UTUC; another 33% eventually developed carcinoma of the bladder without UTUC.
キーワード carcinoma in situ carcinoma of the bladder upper tract urothelial carcinoma ureteroscopy urine cytology
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-06
巻 71巻
号 3号
出版者 Okayama University Medical School
開始ページ 227
終了ページ 232
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28655942
JaLCDOI 10.18926/AMO/55204
フルテキストURL 71_3_219.pdf
著者 Takakura, Hiroaki| Domae, Shohei| Ono, Toshiro| Sasaki, Akira|
抄録  Anticancer drugs induce cell-cycle arrest and apoptosis not only in tumor cells, but also in immune cells. However, many preclinical and clinical findings show that some chemotherapeutic agents can improve the antitumor efficacy of immunotherapy. We immunohistochemically analyzed the degree of immune cell infiltration and the relevance of programmed cell death 1 ligand-1 (PD-L1) expression in surgically resected oral squamous cell carcinoma (OSCC) specimens from patients who had undergone pretreatment with certain chemotherapies and other patients without pretreatment. We divided the patients into the group of neoadjuvant chemotherapy (NAC) patients (n=8) and the nNAC (without NAC) patient group (n=10). We observed that NAC induced infiltrations of CD4, CD8 T cells and CD56 NK cells into the tumor microenvironment. Decreased numbers of Tregs and PD-1-positive cells were observed in the NAC group. No significant difference was observed in the degree of immune-cell infiltration between the patient groups except for CD56 NK cells in the stroma and PD-1 cells in cancer nests. Eighty percent of the nNAC specimens showed intermediate-to-strong PD-L1 protein expression, whereas 75% of the NAC specimens showed down-regulation of the PD-L1 protein, indicating the effectiveness of the chemotherapeutic treatment before surgery.
キーワード oral squamous cell carcinoma programmed cell death 1 ligand-1 tumor microenvironment neoadjuvant chemotherapy immunohistochemistry
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-06
巻 71巻
号 3号
出版者 Okayama University Medical School
開始ページ 219
終了ページ 226
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28655941
JaLCDOI 10.18926/AMO/55201
フルテキストURL 71_3_191.pdf
著者 Kobayashi, Katsuhiro| Akiyama, Tomoyuki| Agari, Takashi| Sasaki, Tatsuya| Shibata, Takashi| Hanaoka, Yoshiyuki| Akiyama, Mari| Endoh, Fumika| Oka, Makio| Date, Isao|
抄録  Electroencephalogram (EEG) data include broadband electrical brain activity ranging from infra-slow bands (< 0.1 Hz) to traditional frequency bands (e.g., the approx. 10 Hz alpha rhythm) to high-frequency bands of up to 500 Hz. High-frequency oscillations (HFOs) including ripple and fast ripple oscillations (80-200 Hz and>200 / 250 Hz, respectively) are particularly of note due to their very close relationship to epileptogenicity, with the possibility that they could function as a surrogate biomarker of epileptogenicity. In contrast, physiological high-frequency activity plays an important role in higher brain functions, and the differentiation between pathological / epileptic and physiological HFOs is a critical issue, especially in epilepsy surgery. HFOs were initially recorded with intracranial electrodes in patients with intractable epilepsy as part of a long-term invasive seizure monitoring study. However, fast oscillations (FOs) in the ripple and gamma bands (40-80 Hz) are now noninvasively detected by scalp EEG and magnetoencephalography, and thus the scope of studies on HFOs /FOs is rapidly expanding.
キーワード fast oscillations, epilepsy electroencephalogram time-frequency analysis
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2017-06
巻 71巻
号 3号
出版者 Okayama University Medical School
開始ページ 191
終了ページ 200
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28655938
フルテキストURL K0005453_other1.pdf
著者 Nobumoto, Etsuko| Masuyama, Hisashi| Hiramatsu, Yuji| Sugiyama, Takashi| Kusaka, Hideto| Toyoda, Nagayasu|
キーワード New GDM criteria Perinatal complications Obesity 75-g oral glucose tolerance test
備考 The final publication is available at Springer| 学位審査副論文|
発行日 2015-09
出版物タイトル Diabetology International
巻 6巻
号 3号
出版者 Springer Japan
開始ページ 226
終了ページ 231
ISSN 21901678
NCID AA12503387
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
DOI 10.1007/s13340-014-0193-8
Web of Science KeyUT 000366631000009
関連URL http://doi.org/10.1007/s13340-014-0193-8 http://ousar.lib.okayama-u.ac.jp/55005
著者 Kondo, Mariko| Mori, Kazuo| Nomura, Hiroshi| Kadowaki, Hanako| Watanabe, Makiko| Doi, Akemi| Shima, Sayaka|
発行日 2016-12-29
出版物タイトル Bioethics - Medical, Ethical and Legal Perspectives
資料タイプ 図書
フルテキストURL K0005517_abstract_review.pdf K0005517_fulltext.pdf K0005517_summary.pdf
著者 松井 美由紀|
発行日 2017-03-24
資料タイプ 学位論文
学位授与番号 甲第5517号
学位授与年月日 2017-03-24
学位・専攻分野 博士(看護学)
授与大学 岡山大学
言語 日本語
フルテキストURL K0005475_abstract_review.pdf K0005475_summary.pdf K0005475_fulltext.pdf
著者 鍛治園 誠|
発行日 2017-03-24
資料タイプ 学位論文
学位授与番号 甲第5475号
学位授与年月日 2017-03-24
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
フルテキストURL K0005468_abstract_review.pdf K0005468_summary.pdf K0005468_fulltext.pdf K0005468_others.pdf
著者 垣尾 勇樹|
発行日 2017-03-24
資料タイプ 学位論文
学位授与番号 甲第5468号
学位授与年月日 2017-03-24
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
フルテキストURL K0005466_abstract_review.pdf K0005466_summary.pdf K0005466_fulltext.pdf
著者 下村 泰之|
発行日 2017-03-24
資料タイプ 学位論文
学位授与番号 甲第5466号
学位授与年月日 2017-03-24
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
著作権者 Copyright © 2017 by The Japanese Society of Internal Medicine
フルテキストURL K0005454_abstract_review.pdf K0005454_summary.pdf K0005454_fulltext.pdf
著者 山根 健太郎|
発行日 2017-03-24
資料タイプ 学位論文
学位授与番号 甲第5454号
学位授与年月日 2017-03-24
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語