検索結果 47942 件
| 著者 | 神内 数義| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 前田 恭弘| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 中尾 保郎| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 西井 笑美子| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 森 正守| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 岡田 由夫| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 岡田 由夫| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 水田 栄三郎| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 水田 栄三郎| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 水田 栄三郎| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 水田 栄三郎| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 国原 角三| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 池田 寿真| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 池田 寿真| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 宮田 信〓| |
|---|---|
| 発行日 | 1959-11-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 12-1号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/41327 |
|---|---|
| フルテキストURL | 64_6_407.pdf |
| 著者 | Ogata, Sho| Horio, Takuya| Sugiura, Yoshiaki| Shimazaki, Hideyuki| Saito, Hiroki| Aiko, Satoshi| Nakanishi, Kuniaki| Kawai, Toshiaki| |
| 抄録 | Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma occurred within the liver, which was probably involved as a result of systemic sarcoidosis. A 57-year-old Japanese man had been followed up for 2 years because of diabetic nephropathy and sarcoidosis. On admission for pneumonia, imaging studies revealed an unexpected hepatic tumor. Histology revealed a hepatocellular carcinoma accompanied by T-lymphocytic infiltration and marked granulomatous inflammation, which was surrounding some tumor nodules. The background liver parenchyma exhibited a moderate degree of fibrosis with granulomatous inflammation. The patient had no other apparent liver disease such as viral hepatitis, steatohepatitis, or primary biliary cirrhosis. Therefore, in the present case, sarcoidosis may be considered the probable background etiology for hepatocarcinogenesis. |
| キーワード | granuloma hepatocellular carcinoma lymphocytic infiltration sarcoidosis |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2010-12 |
| 巻 | 64巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 407 |
| 終了ページ | 410 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21173811 |
| Web of Science KeyUT | 000285664200008 |
| JaLCDOI | 10.18926/AMO/41326 |
|---|---|
| フルテキストURL | 64_6_399.pdf |
| 著者 | Chang, Chin-Hsien| Chen, Kuo-Ti| Lee, Tsong-Hai| Wang, Chao-Hung| Kuo, Yi-Wen| Chiu, Ya-Huang| Hsieh, Ching-Liang| Wu, Chang-Jer| Chang, Yen-Lin| |
| 抄録 | Vascular endothelial damage has been found to be associated with thrombus formation, which is considered to be a risk factor for cardiovascular disease. A diet of natto leads to a low prevalence of cardiovascular disease. The aim of the present study was to investigate the effects of natto extract on vascular endothelia damage with exposure to laser irradiation. Endothelial damage both in vitro and in vivo was induced by irradiation of rose bengal using a DPSS green laser. Cell viability was determined by MTS assay, and the intimal thickening was verified by a histological approach. The antioxidant content of natto extract was determined for the free radical scavenging activity. Endothelial cells were injured in the presence of rose bengal irradiated in a dose-dependent manner. Natto extract exhibits high levels of antioxidant activity compared with purified natto kinase. Apoptosis of laser-injured endothelial cells was significantly reduced in the presence of natto extract. Both the natto extract and natto kinase suppressed intimal thickening in rats with endothelial injury. The present findings suggest that natto extract suppresses vessel thickening as a synergic effect attributed to its antioxidant and anti-apoptosis properties. |
| キーワード | laser irradiation natto extract thrombolysis thrombosis |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2010-12 |
| 巻 | 64巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 399 |
| 終了ページ | 406 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21173810 |
| Web of Science KeyUT | 000285664200007 |
| JaLCDOI | 10.18926/AMO/41325 |
|---|---|
| フルテキストURL | 64_6_391.pdf |
| 著者 | Suezawa, Takanori| Ishino, Kozo| Honjo, Osami| Osaki, Satoru| Kotani, Yasuhiro| Sano, Shunji| |
| 抄録 | We developed a new cardiopulmonary bypass (CPB) method to minimize myocardial damage during aortic arch reconstruction. In this method, coronary flow and heartbeat were stabilized by maintaining the aortic root pressure with an adjusted preload of the ventricle during aortic cross-clamping. This study was performed to determine the appropriate root pressure to maintain the heartbeat without causing deterioration of ventricular function. Study 1. Under partial CPB, the ascending aorta was cross-clamped in 6 pigs (group 1). Experimental data at various systolic aortic root pressures was analysed to determine the appropriate root pressure. Study 2. In group 2 (control, n＝6), the aorta was not clamped, while in group 3 (n＝6), the aorta was cross-clamped for 60 min and the systolic aortic root pressure was maintained at the pressure determined in study 1. Study 1. The diastolic coronary flow was stabilized at values comparable to that before initiation of CPB (6.6±1.4ml/beat) when the systolic aortic root pressure was above 80mmHg. Intracardiac pressure and the myocardial oxygen consumption (MvO2) seemed to be acceptable when the systolic aortic root pressure was below 100mmHg. Therefore, 90mmHg was selected for study 2. Study 2. Perioperative cardiac function did not differ between the groups. We concluded that 90mmHg was the systolic aortic root pressure appropriate for this method. |
| キーワード | aortic cross-clamp coronary flow root pressure cardiopulmonary bypass arch repair |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2010-12 |
| 巻 | 64巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 391 |
| 終了ページ | 397 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21173809 |
| Web of Science KeyUT | 000285664200006 |
| JaLCDOI | 10.18926/AMO/41324 |
|---|---|
| フルテキストURL | 64_6_385.pdf |
| 著者 | Miyatake, Nobuyuki| Moriyasu, Hideyuki| Sakano, Noriko| Tada, Shinya| Suzue, Takeshi| Hirao, Tomohiro| |
| 抄録 | The link between changes in estimated glomerular filtration rate (eGFR) and cigarette smoking was evaluated in Japanese male workers with a 5-year follow-up. We examined the data of 456 Japanese male workers, aged 22-70 years, who were taking no medications, and from this group, 286 men (43.5±8.2 years) were followed for 5-years. Habits of cigarette smoking were obtained during interviews by well-trained staff. The influence of cigarette smoking on eGFR was evaluated. In the first analysis, there was no significant difference in eGFR between subjects with and without cigarette smoking. In the second analysis, eGFR was significantly reduced after 5 years in all subjects. Changes in eGFR in subjects with cigarette smoking (－1.90±12.31ml/min/1.73m2) were significantly smaller than those in subjects without cigarette smoking (－4.97±12.05ml/min/1.73m2). At follow-up, we found that eGFR was weakly and negatively correlated with the number of cigarettes smoked (/day). The present study indicated that cigarette smoking may be an important modifiable factor for eGFR in Japanese male workers who are not taking any medications. |
| キーワード | cigarette smoking estimated glomerular filtration rate (eGFR) male worker |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2010-12 |
| 巻 | 64巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 385 |
| 終了ページ | 390 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21173808 |
| Web of Science KeyUT | 000285664200005 |
| JaLCDOI | 10.18926/AMO/41323 |
|---|---|
| フルテキストURL | 64_6_375.pdf |
| 著者 | Kariya, Shin| Cureoglu, Sebahattin| Fukushima, Hisaki| Morita, Norimasa| Baylan, Muzeyyen Y.| Maeda, Yukihide| Nishizaki, Kazunori| Paparella, Michael M.| |
| 抄録 | This study examined whether pathological findings were present in cochlear vessels for patients with diabetes mellitus. Twenty-six temporal bones from 13 patients with type 1 diabetes mellitus and 40 temporal bones from 20 patients with type 2 diabetes mellitus were examined. Type 2 diabetic temporal bones were divided into 2 groups according to diabetic management (22 temporal bones with insulin therapy, and 18 with oral hypoglycemic drugs). Age-matched normal control temporal bones were also selected. The vessel wall thickness in the cochlear spiral modiolar artery was measured under a light microscope, and the vessel wall ratio (vessel wall thickness/outer diameter of the vessel×100) was calculated. The vessel wall thickness and vessel wall ratio in type 1 diabetes mellitus were significantly greater than in normal controls. Type 2 diabetic patients with insulin therapy showed significantly greater vessel wall thickness and vessel wall ratios than controls. In type 2 diabetes mellitus, the vessel wall thickness and vessel wall ratio were greater in patients treated with insulin therapy than in those treated with oral hypoglycemic agents. Type 2 diabetic patients with insulin therapy showed an increased vessel wall thickness and vessel wall ratio compared to patients with type 1 diabetes mellitus. In conclusion, the cochlea in patients with diabetes mellitus shows circulatory disturbance compared to age-matched normal controls. |
| キーワード | diabetes mellitus temporal bone cochlear spiral modiolar artery hearing loss |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2010-12 |
| 巻 | 64巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 375 |
| 終了ページ | 383 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21173807 |
| Web of Science KeyUT | 000285664200004 |