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JaLCDOI 10.18926/40241
タイトル(別表記) Clinical Studies on Anemia in Rheumatoid Arthritis (II)
フルテキストURL 026_031_049.pdf
著者 山本 泰久|
抄録 II. Iron Metabolism 1. The serum iron: The serum iron was estimated by the method of Umemoto and Yamamoto (by means of o-nitroso resorcinmonomethylether) The average serum iron level of 33 cases with rheumatoid arthritis was 47γ/100 ml., and in 27 of 33 cases (82%) the serum iron levels were shown to be below the lower limit of the normal range (5% rejection limit: 54-141γ/100 ml. ), but the concentrations of serum iron of neuralgias (degenerative Spondylosis, sciatica and painful shoulder) were mostly within the normal range. 2. Iron absorption: To investigate the possible role of poor absorption in preventing a response to oral iron therapy, the changes in serum iron were followed after a test of iron by mouth in 16 caseS with rheumatoid arthritis. The test dose was 1 gm. of reduced iron given with 30 mI. of lemonade-pepsin solution to preserve the iron in the ferrous state and obviate the effects of possible achlorhydria in rheumatoid patients. The results may be grouped under three headings: a) Large rise in serum iron: good adsorption. Three caseS (19%) showed a very large rise in serum iron after the test dose, which is similar to simple iron-deficiency anemia. b) Slight rise in serum iron: presumed poor absorption. Six cases (38%) showed a very small or negligible rise after the test dose, so that at its peak the serum iron was below the normal range. c) In the remaining 7 cases, a maximal rise in serum iron after the test dose was within the normal range. 3. The iron-binding capacity of the serum: The iron-binding capacity of the serum was estimated by means of intravenous injection of Gluferricon (Fe content: 10 mg.). The mean total iron-binding capacity of the serum in the present 13 cases with rheumatoid arthritis was 273γ/100ml., virtually the same as the normal figure (287γ /100 ml.). The degree of saturation of the iron-binding protein with iron was found to lie between 18 and 45% (average: 34%) in control sUbjects and between 7 and 24% (average: 16%) in rheumatoid patients. 4. The serum copper: The serum copper was estimated by means of diethyldithiocarbamate in rheumatoid arthritis with the following results. Healthy subjects: men (15 cases): mean 89.9±14.8γ /l00 ml., women (15 cases): mean 99.9± 12.6γ/100 ml. There is no significant difference between the two. In 10 of 17 cases (57%) with rheumatoid arthritis, the serum copper levels were shown to be above the upper limit of the normal range (57-138γ/100 ml. ・・・5% rejection limit), neuralgias were mostly (92%) within the normal range. The results of investigations upon alternations in iron metabolism of rheumatoid anemia are reported. 1. The serum iron concentration was usually reduced. 2. The intestinal absorption of iron after a single dose of 1 gm. of reduced iron was variable. Strong presumptive evidence of impaired absorption waS recognised in many cases, but some cases gave the excellent absorption. From these results, it seems that simple iron deficiency exist in some anemic caseS of rheumatoid arthritis. 3. The total iron-binding capacity of the serum was slightly reduced. 4. The degree of Saturation of iron-binding protein with iron was below nornal. 5. The serum copper concentration waS usually elevated.
出版物タイトル 岡山大学温泉研究所報告
発行日 1959-10
26巻
開始ページ 31
終了ページ 49
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
JaLCDOI 10.18926/40240
タイトル(別表記) Clinical Study on the Treatment of Rheumatoid Arthritis Part III. Experiences of Capsulosynovectomia Genu Anterior Totalis for Rheumatoid Arthritis
フルテキストURL 026_020_030.pdf
著者 泉 友圀|
抄録 Capsulosynovectomia genu anterior totalis was performed on five cases had marked hydrops and capsular thickening of joints, in which intraarticular injection of hydrocortisone or prednisolone, balneotherapy and hydrotherapy had been repeated in vain for long period with long standing pain and gradual decrease in motor function. The progress was observed for six to seventeen months after the operation, obtaining following results. Rheumatic symptoms were significantly improved after operation and restortion of function was also valuable. No exacerbations in the other joints and general condition were noted with rather improvement in the sign. Further, these operated joints became to react better, differ from preoperative, to balneotherapy and "Fango" with noticeable effects on the restoration of articular function. In histological findings of the resected synovia four cases showed Rs. and one Fr. by T. Kodama's classification. It is, therefore, recommended to appreciate this kind of operation on the cases shown no effects in the treatment of adrenocortical hormone or hot spring bath, which led to the decrease in gait ability, on the standpoint of medical rehabilitation.
出版物タイトル 岡山大学温泉研究所報告
発行日 1959-10
26巻
開始ページ 20
終了ページ 30
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
JaLCDOI 10.18926/40239
タイトル(別表記) Clinical Study on the Treatment of Rheumatoid Arthritis Part II. Experiences of Intraarticular Injection of Prednisolone for Rheumatoid Arthritis
フルテキストURL 026_008_019.pdf
著者 泉 友圀|
抄録 Meticorterone (Prednisolone acetate) were injected into joints of 33 cases of rheumatoid arthritis, 172 times in total, with better results. Although intraarticular injection of prednisolone is, at present, to be one of the most effective treatment for rheumatoid arthritis, one must pay attention at the appearance of general effect in frequent and abundant injection. Comparative studies were performed on the effects of intraarticular injectons of prednisolone T. B. A, (on twelve cases), hydrocortisone acetate and meticorterone. Prednisolone T. B. A. was proved markedly longer effect in local with minimum general effect, It was, therefore, thought that prednisolone T. B. A. was safest and most effective in intraarticular therapy on the rheumatoid arthritis.
出版物タイトル 岡山大学温泉研究所報告
発行日 1959-10
26巻
開始ページ 8
終了ページ 19
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
JaLCDOI 10.18926/40238
タイトル(別表記) Clinical Study on the Treatment of Rheumatoid Arthritis Part I. Therapeutic Experiences by Hot Spring Bath and "Fango" using Clay of Nigyo-pass
フルテキストURL pitsr_026_001_007.pdf
著者 泉 友圀|
抄録 Rheumatoid arthritis, thought incurable for many years, was treated by radioactive hot spring bath and uranium deposit clay at Ningyo-pass. The therapeutic effects of balneotherapy and "Fango" were stUdied comparatively. Results of hot spring bath for one month were effective in 63 of 73 cases (86.3 per cent), and 60 per cent even in (222) chr., in which attaind Grade III. It was thought that therapeutic effect of bathing on (222) chr. was increased using together with adrenocortical hormone. Uranium deposit clay at Ningyo-pass was used on 59 cases of this disease, in form of "Fango" and local bath in mud. It was effective in 60.8 per cent of 171 joints, and in 53.4 per cent of 131 joints of (222) chr. It showed that this was valuable as a local therapy for those incurable types of the disease.
出版物タイトル 岡山大学温泉研究所報告
発行日 1959-10
26巻
開始ページ 1
終了ページ 7
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002462886
著者 岡山大学温泉研究所|
発行日 1959-10
出版物タイトル 岡山大学温泉研究所報告
26巻
資料タイプ その他
JaLCDOI 10.18926/40236
タイトル(別表記) Geochemical Studies on the Area of Hot Springs in Hamamura and Shikano District Comparison of Characteristics of Hot Springs in the Central part of Tottori Prefecture, Japan
フルテキストURL 027_025_044.pdf
著者 阪上 正信| 御船 政明|
抄録 The thermal and ground waters were sampled in the hot springs district of Hamamura-Katsumi and Shikano and in their neighborhoods. The water temperatures were measured when they were sampled. Among the major chemical constituents, the chloride, sulfate, bicarbonate (methyl-orange alkalinity), calcium and magnesium content was determined. Furthermore, as the minor constituents, the arsenic and phosphorus content was also determined. The uranium, radium and radon content was determined in some samples of hot springs. Based on the results of chemical analysis, the relations between the chloride content and the content of other chemical constituents were cheked respectively. Positive correlations were found in the relations between water temperature-Cl(-), SO(4)(2-)-Cl(-), Ca(2+)-Cl(-) and As-Cl(-), although the ratios of each content showed the different characteristic in Hamamura-Katsumi compared with that in Shikano. In the samples of Hamamura-Katsumi where the thermal waters were pumped out from the sedimentary beds of volcanic rocks, the sulfate and calcium content was relatively richer compared with the content of these ions in the samples of Shikano where granitic rocks underlay as the basement in the fairly shallow depth from the cground surface. These characteristics were also noticed when the chemical compositions of other hot springs in the central part of Tottori prefecture were examined. In the neighborhood of the hot springs district mentioned-above, distinctive indications of hot spring were found at Kinashi which was placed between Hamamura and Shikano, comprehensively examining the content of chemical constituents in the ground water samples in this region.
出版物タイトル 岡山大学温泉研究所報告
発行日 1961-01
27巻
開始ページ 25
終了ページ 44
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 40017532371
JaLCDOI 10.18926/40235
フルテキストURL pitsr_027_011_023.pdf
著者 杉山 隆二|
出版物タイトル 岡山大学温泉研究所報告
発行日 1961-01
27巻
開始ページ 11
終了ページ 23
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002462885
JaLCDOI 10.18926/40234
フルテキストURL pitsr_027_001_009.pdf
著者 Sakanoue, Masanobu|
抄録 In recent years, coulometric analysis has been developed and widely used as a technique for the determination of substances in solution by measuring the quantity of electricity required for the completion of a reaction in an electrolysis cell. Of two coulometric techniques, i. e., coulometric titration with a constant current and coulometric analysis with a controlled potential of a working electrode, the latter is more interesting to the author, because by this method both electrolytic separation and quantitative determination of chemical species can be achieved simultaneously. Especially, the use of a mercury cathode as the working electrode(1)) has an advantage that the optimum control potentials can easily be determinable from polarographic data. In our laboratory, we took up the coulometry of uranium as one of the interesting themes of researches when we had an opPortunity in studying various kinds of analytical methods for uranium in accordance with the request by Japan Atomic Fuel Corporation. The coulometric determination of uranium (VI) by using a mercury cathode at a controlled potential was studied by G. L. Booman, W. B. Holbrook and ]. E. Rein(2)). It was found to be very useful for the analysis of uranium in a highly enriched nuclear element which underwent fission to an appreciable extent. But the instrument used by them(3)) was complicated and expensive. Therefore, a simple counter millicoulometer has been coustructed in our laboratory, a readymade potentiostat (electrical instrument for automatic controlled potential electrolysis) being tried for electrolysis. By these instruments, the author studied the fundam ental conditions of coulometry for uranium and tried the successive determinations of uranium and thallium in mixed solutions.
出版物タイトル 岡山大学温泉研究所報告
発行日 1961-01
27巻
開始ページ 1
終了ページ 9
ISSN 0369-7142
言語 英語
論文のバージョン publisher
NAID 120002462884
著者 岡山大学温泉研究所|
発行日 1961-01
出版物タイトル 岡山大学温泉研究所報告
27巻
資料タイプ その他
著者 森永 寛|
発行日 1961-03
出版物タイトル 岡山大学温泉研究所報告
28巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1961-03
出版物タイトル 岡山大学温泉研究所報告
28巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1961-03
出版物タイトル 岡山大学温泉研究所報告
28巻
資料タイプ その他
JaLCDOI 10.18926/40229
フルテキストURL 028_008_012.pdf
著者 森永 寛|
出版物タイトル 岡山大学温泉研究所報告
発行日 1961-03
28巻
開始ページ 8
終了ページ 12
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 40018217662
著者 八木 日出雄|
発行日 1961-03
出版物タイトル 岡山大学温泉研究所報告
28巻
資料タイプ 会議発表用資料
著者 八木 日出雄|
発行日 1961-03
出版物タイトル 岡山大学温泉研究所報告
28巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1961-03
出版物タイトル 岡山大学温泉研究所報告
28巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1961-06-25
出版物タイトル 岡山大学温泉研究所報告
29巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1961-06-25
出版物タイトル 岡山大学温泉研究所報告
29巻
資料タイプ その他
JaLCDOI 10.18926/40223
タイトル(別表記) Chemcal Study on a Spring Well in Tottori Hot Springs
フルテキストURL pitsr_029_050_056.pdf
著者 阪上 正信| 杉原 健|
出版物タイトル 岡山大学温泉研究所報告
発行日 1961-06-25
29巻
開始ページ 50
終了ページ 56
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002462883
JaLCDOI 10.18926/40222
タイトル(別表記) CHEMICAL STUDY ON SEKIGANE HOT SPRINGS, TOTTORI-KEN
フルテキストURL pitsr_029_038_049.pdf
著者 阪上 正信| 御船 政明|
抄録 The chemical and physical characteristics of the thermal and ground waters in Sekigane Hot Springs were determined. The content of the following chemical constituents was determined: Cl(-), S0(4)(2-), HCO(3)(-), Ca(2+), As, F, U and Ra. The relationship between water temperature and depth of spring wens was found to be indicative of the presence of a fissure, in agreement with the conclusion reached geologically by Sugiyama. The water temperature, the e1ectricconductivity and the content of chemical constituents of the ground water were as expected markedly lower than those of the thermal water. As a whole, however, the water temperature, the electricconductivity and the content of SO(4)(2-), HCO(3)(-), Ca(2+), As and F are in positive and linear correlation with the Cl- content. In other words, these characteristics of the waters, excluding the U and Ra content, correlate positively and linearly with each other. This was interpreted to mean that a thermal water of high salinity is simply diluted by a cold ground water of very low salinity, and that a ground water of relatively high salinity is contaminated by thermal water. The content of U and Ra of these spring waters is lower than that of the spring waters in Ikeda, Shimane-ken, and Misasa, Tottori-ken, where radioactive springs also issue. Finally, it is concluded that As and F will be as useful as Cl- in chemically locating a new site for a spring well in Sekigane because of the low contamination due to human life of ground water by these elements.
出版物タイトル 岡山大学温泉研究所報告
発行日 1961-06-25
29巻
開始ページ 38
終了ページ 49
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/21348
言語 日本語
論文のバージョン publisher
NAID 120002462882