start-ver=1.4 cd-journal=joma no-vol=192 cd-vols= no-issue=5 article-no= start-page=58 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250416 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The Intertwining Property for Laguerre Processes with a Fixed Parameter en-subtitle= kn-subtitle= en-abstract= kn-abstract=We investigate the intertwining of Laguerre processes of parameter α in different dimensions. We introduce a Feller kernel that depends on α and intertwines the α-Laguerre process in N + 1 dimensions and that in N dimensions. When α is a non-negative integer, the new kernel is interpreted in terms of the conditional distribution of the squared singular values: if the singular values of a unitarily invariant random matrix of order (N+α+1)×(N+1) are fixed, then the those of its (N+α) × N truncation matrix are given by the new kernel. en-copyright= kn-copyright= en-aut-name=BufetovAlexander I. en-aut-sei=Bufetov en-aut-mei=Alexander I. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KawamotoYosuke en-aut-sei=Kawamoto en-aut-mei=Yosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Steklov Mathematical Institute of RAS kn-affil= affil-num=2 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= en-keyword=Random matrices kn-keyword=Random matrices en-keyword=Intertwining relation kn-keyword=Intertwining relation en-keyword=Interacting Brownian motions kn-keyword=Interacting Brownian motions END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250508 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Comprehensive analysis of adverse event profile changes with pertuzumab addition to trastuzumab‐based breast cancer therapy: Disproportionality analysis using VigiBase en-subtitle= kn-subtitle= en-abstract= kn-abstract=Aims: Pertuzumab is used in combination with trastuzumab-based therapy for HER2-positive breast cancer. However, real-world safety information on pertuzumab remains limited. This study assessed the safety of adding pertuzumab to trastuzumab-based therapy for HER2-positive breast cancer using real-world data.
Methods: VigiBase, the World Health Organization's global database of adverse events (AEs), containing reports from November 1967 to December 2023, was used. Signals for pertuzumab-associated AEs in breast cancer cases were detected using the reporting odds ratio (ROR).
Results: Signals of trastuzumab plus pertuzumab relative to trastuzumab alone were detected in gastrointestinal disorders (ROR: 1.45, 95% confidence interval: 1.26–1.67), including diarrhoea (3.49, 2.83–4.30); infections and infestations (1.54, 1.24–1.91); and skin and subcutaneous tissue disorders (ROR: 1.63, 1.40–1.90), including pruritus (1.96, 1.51–2.55) and rash (1.63, 1.20–2.23). Further, signals of trastuzumab plus docetaxel plus pertuzumab relative to those of trastuzumab plus docetaxel were detected in gastrointestinal disorders (1.63, 1.38–1.93), including nausea (1.72, 1.24–2.39) and vomiting (1.48, 1.01–2.17), and in nervous system disorders (1.50, 1.20–1.87), including paraesthesia (2.60, 1.33–5.08) and peripheral sensory neuropathy (5.94, 1.79–19.71). The frequency of AEs causing or prolonging hospitalization was increased with trastuzumab plus pertuzumab compared to that with trastuzumab alone (1.18, 1.00–1.38).
Conclusions: AE profiles after the addition of pertuzumab to trastuzumab-based therapy were comprehensively identified. The findings in this study highlight the importance of considering these AEs when selecting pertuzumab combination therapy to ensure the safety of patients with breast cancer. en-copyright= kn-copyright= en-aut-name=TakedaTatsuaki en-aut-sei=Takeda en-aut-mei=Tatsuaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MatsumotoJun en-aut-sei=Matsumoto en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SakaiTomonori en-aut-sei=Sakai en-aut-mei=Tomonori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=IwataNaohiro en-aut-sei=Iwata en-aut-mei=Naohiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HamanoHirofumi en-aut-sei=Hamano en-aut-mei=Hirofumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KoyamaToshihiro en-aut-sei=Koyama en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AriyoshiNoritaka en-aut-sei=Ariyoshi en-aut-mei=Noritaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=ZamamiYoshito en-aut-sei=Zamami en-aut-mei=Yoshito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Education and Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Education and Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil= affil-num=4 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil= affil-num=5 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil= affil-num=6 en-affil=Department of Health Data Science, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=7 en-affil=Department of Education and Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= affil-num=8 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil= en-keyword=adverse event kn-keyword=adverse event en-keyword=breast cancer kn-keyword=breast cancer en-keyword=pertuzumab kn-keyword=pertuzumab en-keyword=trastuzumab kn-keyword=trastuzumab en-keyword=VigiBase kn-keyword=VigiBase END start-ver=1.4 cd-journal=joma no-vol=3 cd-vols= no-issue= article-no= start-page=22 end-page=54 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Forming a mindset of A consideration on being a burden : Relationship with education kn-title=迷惑をかけたくない意識の形成―教育との関係― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=DENGXiaofan en-aut-sei=DENG en-aut-mei=Xiaofan kn-aut-name=鄧小凡 kn-aut-sei=鄧 kn-aut-mei=小凡 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院ヘルスシステム統合科学研究科 END start-ver=1.4 cd-journal=joma no-vol=27 cd-vols= no-issue=18 article-no= start-page=4737 end-page=4741 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250429 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Electrochemical Oxidation of Benzyl Alcohols via Hydrogen Atom Transfer Mediated by 2,2,2-Trifluoroethanol en-subtitle= kn-subtitle= en-abstract= kn-abstract=We report a novel electrochemical oxidation of benzyl alcohols. We found that trifluoroethanol plays a role as a hydrogen atom transfer (HAT) mediator, enabling the oxidation of electron-deficient substrates that are difficult to directly oxidize on electrode surfaces. Density functional theory calculations, cyclic voltammetry measurements, and constant potential electrolysis studies supported the proposed HAT mechanism. Moreover, the obtained carbonyl compounds could be functionalized in an electrochemical one-pot manner, further highlighting their synthetic utility. en-copyright= kn-copyright= en-aut-name=KawajiriTakahiro en-aut-sei=Kawajiri en-aut-mei=Takahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HosoyaMasahiro en-aut-sei=Hosoya en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=GodaSatoshi en-aut-sei=Goda en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SatoEisuke en-aut-sei=Sato en-aut-mei=Eisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SugaSeiji en-aut-sei=Suga en-aut-mei=Seiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=API R&D Laboratory, Research Division, Shionogi & Co., Ltd. kn-affil= affil-num=2 en-affil=API R&D Laboratory, Research Division, Shionogi & Co., Ltd. kn-affil= affil-num=3 en-affil=API R&D Laboratory, Research Division, Shionogi & Co., Ltd. kn-affil= affil-num=4 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=26 cd-vols= no-issue=5 article-no= start-page=e70087 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250512 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Genomic Islands of Pseudomonas syringae pv. tabaci 6605: Identification of PtaGI-1 as a Pathogenicity Island With Effector Genes and a Tabtoxin Cluster en-subtitle= kn-subtitle= en-abstract= kn-abstract=Genomic islands (GIs) are 20-500 kb DNA regions that are thought to be acquired by horizontal gene transfer. GIs that confer pathogenicity and environmental adaptation have been reported in Pseudomonas species; however, GIs that enhance bacterial virulence have not. Here, we identified 110 kb and 103 kb GIs in P. syringae pv. tabaci 6605 (Pta6605), the causative agent of tobacco wildfire disease, which has the ability to produce tabtoxin as a phytotoxin. These GIs are partially homologous to known genomic islands in Pseudomonas aeruginosa and P. syringae pv. phaseolicola and were designated PtaGI-1 and PtaGI-2. Both PtaGIs conserve core genes, whereas each GI possesses different accessory genes. PtaGI-1 contains a tabtoxin biosynthetic gene cluster and three type III effector genes among its accessory genes, whereas PtaGI-2 also contains homologous genes to hsvABC, pathogenicity-related genes in Erwinia amylovora. Inoculation revealed that the PtaGI-1 mutant, but not the PtaGI-2 mutant, lost the ability to biosynthesise tabtoxin and to cause disease. Therefore, PtaGI-1 is thought to be a pathogenicity island. Both PtaGI-1 and PtaGI-2 have a pseudogene of tRNALys on the left border and an intact tRNALys gene on the right border. In a colony of Pta6605, both GIs can be excised at tRNALys, and PtaGI-1 and PtaGI-2 exist in a circular form. These results indicate that tabtoxin biosynthesis genes in PtaGI-1 are required for disease development, and PtaGI-1 is necessary for Pta6605 virulence. en-copyright= kn-copyright= en-aut-name=WatanabeYuta en-aut-sei=Watanabe en-aut-mei=Yuta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KunishiKotomi en-aut-sei=Kunishi en-aut-mei=Kotomi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MatsuiHidenori en-aut-sei=Matsui en-aut-mei=Hidenori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SakataNanami en-aut-sei=Sakata en-aut-mei=Nanami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NoutoshiYoshiteru en-aut-sei=Noutoshi en-aut-mei=Yoshiteru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ToyodaKazuhiro en-aut-sei=Toyoda en-aut-mei=Kazuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=IchinoseYuki en-aut-sei=Ichinose en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=The Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Faculty of Agriculture,Okayama University kn-affil= affil-num=3 en-affil=The Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=The Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=The Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=6 en-affil=The Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=7 en-affil=The Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= en-keyword=horizontal gene transfer kn-keyword=horizontal gene transfer en-keyword=integrative and conjugative elements kn-keyword=integrative and conjugative elements en-keyword=pathogenicity island kn-keyword=pathogenicity island en-keyword=Pseudomonas syringae kn-keyword=Pseudomonas syringae en-keyword=tabtoxin kn-keyword=tabtoxin END start-ver=1.4 cd-journal=joma no-vol=19 cd-vols= no-issue=2 article-no= start-page=94 end-page=100 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=2025 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Effects of different management approaches on unmet water demand in coffee-producing areas during wet and dry years: a case study of the Srepok River Watershed, Vietnam en-subtitle= kn-subtitle= en-abstract= kn-abstract=The primary cause of conflicts over water allocation is growing demand and limited supply, which has become an increasingly serious issue in many watersheds. To alleviate water disputes, effective management strategies can be employed, particularly in the context of intensifying agricultural production and unpredictable changes in weather. In this study, two models, SWAT and WEAP, and the modified surface water supply index (MSWSI) were utilized to evaluate water allocation in the Srepok River Watershed (SRW), considering the prioritization of demand and various irrigation methods, during both wet and dry years. The crop irrigation was chosen to be the main focus in relation to the unmet water demand (UWD). The results indicated that coffee was the primary cause of UWD in the middle of the watershed during the second half of the dry season, and annual crops (AC) were the secondary cause. This research further elucidated that while prioritizing demand had an insignificant impact, transitioning from hose irrigation to sprinkler irrigation could be remarkably effective in mitigating the issues of UWD in coffee crops during both wet and dry years. en-copyright= kn-copyright= en-aut-name=SamTruong Thao en-aut-sei=Sam en-aut-mei=Truong Thao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SomuraHiroaki en-aut-sei=Somura en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MoroizumiToshitsugu en-aut-sei=Moroizumi en-aut-mei=Toshitsugu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= en-keyword=hydrological model kn-keyword=hydrological model en-keyword=drought kn-keyword=drought en-keyword=coffee irrigation kn-keyword=coffee irrigation en-keyword=water-saving technique kn-keyword=water-saving technique en-keyword=water allocation kn-keyword=water allocation END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=1 article-no= start-page=715 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250508 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=TRPV2 mediates stress resilience in mouse cardiomyocytes en-subtitle= kn-subtitle= en-abstract= kn-abstract=The heart dynamically compensates for haemodynamic stress, but how this resilience forms during cardiac growth is not clear. Using a temporally inducible, cardiac-specific knockout in mice we show that the Transient receptor potential vanilloid family 2 (TRPV2) channel is crucial for the maturation of cardiomyocyte stress resilience. TRPV2 defects in growing hearts lead to small morphology, abnormal intercalated discs, weak contractility, and low expression of serum response factor and Insulin-like growth factor-1 (IGF-1) signalling. Individual cardiomyocytes of TRPV2-deficient hearts show reduced contractility with abnormal Ca2+ handling. In cultured neonatal cardiomyocytes, mechanical Ca2+ response, excitation-contraction coupling, sarcoplasmic reticulum Ca2+ content, actin formation, nuclear localisation of Myocyte enhancer factor 2c, and IGF-1 expression require TRPV2. TRPV2-deficient hearts show a defective response to dobutamine stress and no compensatory hypertrophic response to phenylephrine administration, but no stress response to pressure overload. These data suggest TRPV2 mediates the maturation of cardiomyocyte stress resilience, and will advance therapeutic interventions and drug discovery for heart disease. en-copyright= kn-copyright= en-aut-name=DongYubing en-aut-sei=Dong en-aut-mei=Yubing kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=WangGuohao en-aut-sei=Wang en-aut-mei=Guohao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=UjiharaYoshihiro en-aut-sei=Ujihara en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ChenYanzhu en-aut-sei=Chen en-aut-mei=Yanzhu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YoshidaMasashi en-aut-sei=Yoshida en-aut-mei=Masashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NakamuraKazufumi en-aut-sei=Nakamura en-aut-mei=Kazufumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KatanosakaKimiaki en-aut-sei=Katanosaka en-aut-mei=Kimiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NaruseKeiji en-aut-sei=Naruse en-aut-mei=Keiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KatanosakaYuki en-aut-sei=Katanosaka en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil=Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Electrical and Mechanical Engineering, Graduate School of Engineering, Nagoya Institute of Technology kn-affil= affil-num=4 en-affil=Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Chronic Kidney Disease and Cardiovascular Disease, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Cardiovascular Medicine, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University kn-affil= affil-num=8 en-affil=Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=9 en-affil=Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=26 cd-vols= no-issue=5 article-no= start-page=e70091 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250507 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Pseudomonas syringae pv. tabaci 6605 Requires Seven Type III Effectors to Infect Nicotiana benthamiana en-subtitle= kn-subtitle= en-abstract= kn-abstract=Type III effectors (T3Es), virulence factors injected into plant cells via the type III secretion system (T3SS), play essential roles in the infection of host plants. Pseudomonas syringae pv. tabaci 6605 (Pta 6605) is the causal agent of wildfire disease in tobacco and harbours at least 22 T3Es in its genome. However, the specific T3Es required by Pta 6605 to infect Nicotiana benthamiana remain unidentified. In this study, we investigated the T3Es that contribute to Pta 6605 infection of N. benthamiana. We constructed Pta 6605 poly-T3E-deficient mutants (Pta DxE) and inoculated them into N. benthamiana. Flood assay, which mimics natural opening-based entry, showed that mutant strains lacking 14-22 T3Es, namely, Pta D14E-D22E mutants, exhibited reduced disease symptoms. By contrast, infiltration inoculation, which involves direct injection into leaves, showed that the Pta D14E to Pta D20E mutants developed disease symptoms. Notably, the Pta D20E, containing AvrE1 and HopM1, induced weak but observable symptoms upon infiltration inoculation. Conversely, no symptoms were observed in either the flood assay or infiltration inoculation for Pta D21E and Pta D22E. Taken together, these findings indicate that the many T3Es such as AvrPto4/AvrPtoB, HopW1/HopAE1, and HopM1/AvrE1 in Pta 6605 collectively contribute to invasion through natural openings and symptom development in N. benthamiana. This study provides the basis for understanding virulence in the host by identifying the minimum T3E repertoire required by Pta 6605 to infect N. benthamiana. en-copyright= kn-copyright= en-aut-name=KuroeKana en-aut-sei=Kuroe en-aut-mei=Kana kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NishimuraTakafumi en-aut-sei=Nishimura en-aut-mei=Takafumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KashiharaSachi en-aut-sei=Kashihara en-aut-mei=Sachi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SakataNanami en-aut-sei=Sakata en-aut-mei=Nanami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YamamotoMikihiro en-aut-sei=Yamamoto en-aut-mei=Mikihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NoutoshiYoshiteru en-aut-sei=Noutoshi en-aut-mei=Yoshiteru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ToyodaKazuhiro en-aut-sei=Toyoda en-aut-mei=Kazuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=IchinoseYuki en-aut-sei=Ichinose en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=MatsuiHidenori en-aut-sei=Matsui en-aut-mei=Hidenori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=6 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=7 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=8 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=9 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= en-keyword=poly T3E mutant kn-keyword=poly T3E mutant en-keyword=type III effector kn-keyword=type III effector en-keyword=type III secretion system kn-keyword=type III secretion system END start-ver=1.4 cd-journal=joma no-vol=27 cd-vols= no-issue=4 article-no= start-page=043024 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250428 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Characterization of the thorium-229 defect structure in CaF2 crystals en-subtitle= kn-subtitle= en-abstract= kn-abstract=Recent advancements in laser excitation of the low-energy thorium-229 (229Th) nuclear isomeric state in calcium fluoride (CaF2) single crystals render this system a promising candidate for a solid-state nuclear clock. Nonetheless, the precise experimental determination of the microscopic ion configuration surrounding the doped 229Th and its electronic charge state remains a critical challenge. Such characterization is essential for precisely controlling the clock transition and evaluating the performance of this solid-state nuclear clock system. In this study, we use x-ray absorption fine structure spectroscopy of 229Th:CaF2 to investigate the charge state and coordination environment of doped 229Th. The results indicate that 229Th displays a 4+ oxidation state at the substitutional site of a Ca2+ ion, with charge compensated provided by two F− ions positioned at interstitial sites adjacent to 229Th. en-copyright= kn-copyright= en-aut-name=TakatoriS. en-aut-sei=Takatori en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=PimonM. en-aut-sei=Pimon en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=PollittS. en-aut-sei=Pollitt en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=BartokosM. en-aut-sei=Bartokos en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=BeeksK. en-aut-sei=Beeks en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=GrueneisA. en-aut-sei=Grueneis en-aut-mei=A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=HirakiT. en-aut-sei=Hiraki en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=HonmaT. en-aut-sei=Honma en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=HosseiniN. en-aut-sei=Hosseini en-aut-mei=N. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=LeitnerA. en-aut-sei=Leitner en-aut-mei=A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=MasudaT. en-aut-sei=Masuda en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=MorawetzI en-aut-sei=Morawetz en-aut-mei=I kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=NittaK. en-aut-sei=Nitta en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=OkaiK. en-aut-sei=Okai en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=RiebnerT. en-aut-sei=Riebner en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=SchadenF. en-aut-sei=Schaden en-aut-mei=F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= en-aut-name=SchummT. en-aut-sei=Schumm en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=17 ORCID= en-aut-name=SekizawaO. en-aut-sei=Sekizawa en-aut-mei=O. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=18 ORCID= en-aut-name=SikorskyT. en-aut-sei=Sikorsky en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=19 ORCID= en-aut-name=TakahashiY. en-aut-sei=Takahashi en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=20 ORCID= en-aut-name=De ColCol, L. Toscani en-aut-sei=De Col en-aut-mei=Col, L. Toscani kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=21 ORCID= en-aut-name=YamamotoR. en-aut-sei=Yamamoto en-aut-mei=R. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=22 ORCID= en-aut-name=YomogidaT. en-aut-sei=Yomogida en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=23 ORCID= en-aut-name=YoshimiA. en-aut-sei=Yoshimi en-aut-mei=A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=24 ORCID= en-aut-name=YoshimuraK. en-aut-sei=Yoshimura en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=25 ORCID= affil-num=1 en-affil=Research Institute for Interdisciplinary Science (RIIS), Okayama University kn-affil= affil-num=2 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=3 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=4 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=5 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=6 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=7 en-affil=Research Institute for Interdisciplinary Science (RIIS), Okayama University kn-affil= affil-num=8 en-affil=Japan Synchrotron Radiation Research Institute kn-affil= affil-num=9 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=10 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=11 en-affil=Research Institute for Interdisciplinary Science (RIIS), Okayama University kn-affil= affil-num=12 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=13 en-affil=Japan Synchrotron Radiation Research Institute kn-affil= affil-num=14 en-affil=Research Institute for Interdisciplinary Science (RIIS), Okayama University kn-affil= affil-num=15 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=16 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=17 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=18 en-affil=Japan Synchrotron Radiation Research Institute kn-affil= affil-num=19 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=20 en-affil=Department of Earth and Planetary Science, The University of Tokyo kn-affil= affil-num=21 en-affil=Faculty of Physics, TU Wien kn-affil= affil-num=22 en-affil=Research Institute for Interdisciplinary Science (RIIS), Okayama University kn-affil= affil-num=23 en-affil=Department of Earth and Planetary Science, The University of Tokyo kn-affil= affil-num=24 en-affil=Research Institute for Interdisciplinary Science (RIIS), Okayama University kn-affil= affil-num=25 en-affil=Research Institute for Interdisciplinary Science (RIIS), Okayama University kn-affil= en-keyword=solid-state nuclear clock kn-keyword=solid-state nuclear clock en-keyword=thorium-229 kn-keyword=thorium-229 en-keyword=XAFS kn-keyword=XAFS END start-ver=1.4 cd-journal=joma no-vol=220 cd-vols= no-issue= article-no= start-page=115401 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250502 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Genomic landscape and clinical impact of homologous recombination repair gene mutation in small bowel adenocarcinoma en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: Small bowel adenocarcinoma (SBA) is a rare malignancy with a poor prognosis and limited treatment options. Although homologous recombination deficiency has been studied as a biomarker for other cancer types, the clinical and genomic implications of homologous recombination repair (HRR) gene mutations in SBA remain unclear.
Methods: We retrospectively analyzed the data of 628 patients with advanced or recurrent SBA from a nationwide genomic database. Patients were categorized into HRR mutation and non-HRR mutation groups and compared for their clinical and genomic characteristics including tumor mutational burden (TMB) and microsatellite instability-high (MSI-H) were compared. Treatment efficacy and overall survival (OS) were assessed based on HRR gene mutation status and primary tumor site (duodenal adenocarcinoma [DA] vs. small intestinal carcinoma [SIC]).
Results: Patients with the HRR mutations had higher frequencies of TMB and MSI-H than those without the mutation (P < 0.0001). In DA, HRR gene mutation positivity was associated with improved OS and higher overall response rates (ORR) to platinum-based chemotherapy (OS: not reached vs. 23.5 months, P = 0.040; ORR: 33 % vs. 19 %, P = 0.046), whereas no significant associations were observed with SIC.
Conclusion: HRR gene mutation may be a potential biomarker for platinum-based chemotherapy efficacy in SBA, especially in DA, highlighting the need for site-specific therapies. en-copyright= kn-copyright= en-aut-name=OzatoToshiki en-aut-sei=Ozato en-aut-mei=Toshiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KonoYoshiyasu en-aut-sei=Kono en-aut-mei=Yoshiyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HoriguchiShigeru en-aut-sei=Horiguchi en-aut-mei=Shigeru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TsutsumiKoichiro en-aut-sei=Tsutsumi en-aut-mei=Koichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YamamotoHideki en-aut-sei=Yamamoto en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HirasawaAkira en-aut-sei=Hirasawa en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=EnnishiDaisuke en-aut-sei=Ennishi en-aut-mei=Daisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TomidaShuta en-aut-sei=Tomida en-aut-mei=Shuta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=ToyookaShinichi en-aut-sei=Toyooka en-aut-mei=Shinichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=OtsukaMotoyuki en-aut-sei=Otsuka en-aut-mei=Motoyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Gastroenterology and Hepatology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Gastroenterology and Hepatology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Gastroenterology and Hepatology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Gastroenterology, Okayama University Hospital kn-affil= affil-num=5 en-affil=Department of Clinical Genomic Medicine, Okayama University Hospital kn-affil= affil-num=6 en-affil=Department of Clinical Genomic Medicine, Okayama University Hospital kn-affil= affil-num=7 en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital kn-affil= affil-num=8 en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital kn-affil= affil-num=9 en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital kn-affil= affil-num=10 en-affil=Department of Gastroenterology and Hepatology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Homologous recombination repair kn-keyword=Homologous recombination repair en-keyword=Small bowel adenocarcinoma kn-keyword=Small bowel adenocarcinoma en-keyword=Genome kn-keyword=Genome END start-ver=1.4 cd-journal=joma no-vol=16 cd-vols= no-issue=1 article-no= start-page=2323 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250308 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism en-subtitle= kn-subtitle= en-abstract= kn-abstract=Protein synthesis by ribosomes produces functional proteins but also serves diverse regulatory functions, which depend on the coding amino acid sequences. Certain nascent peptides interact with the ribosome exit tunnel to arrest translation and modulate themselves or the expression of downstream genes. However, a comprehensive understanding of the mechanisms of such ribosome stalling and its regulation remains elusive. In this study, we systematically screen for unidentified ribosome arrest peptides through phenotypic evaluation, proteomics, and mass spectrometry analyses, leading to the discovery of the arrest peptides PepNL and NanCL in E. coli. Our cryo-EM study on PepNL reveals a distinct arrest mechanism, in which the N-terminus of PepNL folds back towards the tunnel entrance to prevent the catalytic GGQ motif of the release factor from accessing the peptidyl transferase center, causing translation arrest at the UGA stop codon. Furthermore, unlike sensory arrest peptides that require an arrest inducer, PepNL uses tryptophan as an arrest inhibitor, where Trp-tRNATrp reads through the stop codon. Our findings illuminate the mechanism and regulatory framework of nascent peptide-induced translation arrest, paving the way for exploring regulatory nascent peptides. en-copyright= kn-copyright= en-aut-name=AndoYushin en-aut-sei=Ando en-aut-mei=Yushin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KoboAkinao en-aut-sei=Kobo en-aut-mei=Akinao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NiwaTatsuya en-aut-sei=Niwa en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamakawaAyako en-aut-sei=Yamakawa en-aut-mei=Ayako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KonomaSuzuna en-aut-sei=Konoma en-aut-mei=Suzuna kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KobayashiYuki en-aut-sei=Kobayashi en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=NurekiOsamu en-aut-sei=Nureki en-aut-mei=Osamu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TaguchiHideki en-aut-sei=Taguchi en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=ItohYuzuru en-aut-sei=Itoh en-aut-mei=Yuzuru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=ChadaniYuhei en-aut-sei=Chadani en-aut-mei=Yuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Biological Sciences, Graduate School of Science, The University of Tokyo kn-affil= affil-num=2 en-affil=School of Life Science and Technology, Institute of Science Tokyo kn-affil= affil-num=3 en-affil=School of Life Science and Technology, Institute of Science Tokyo kn-affil= affil-num=4 en-affil=School of Life Science and Technology, Institute of Science Tokyo kn-affil= affil-num=5 en-affil=School of Life Science and Technology, Institute of Science Tokyo kn-affil= affil-num=6 en-affil=School of Life Science and Technology, Institute of Science Tokyo kn-affil= affil-num=7 en-affil=Department of Biological Sciences, Graduate School of Science, The University of Tokyo kn-affil= affil-num=8 en-affil=School of Life Science and Technology, Institute of Science Tokyo kn-affil= affil-num=9 en-affil=Department of Biological Sciences, Graduate School of Science, The University of Tokyo kn-affil= affil-num=10 en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=8 article-no= start-page=e70793 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250418 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Genomic Differences and Distinct TP53 Mutation Site-Linked Chemosensitivity in Early- and Late-Onset Gastric Cancer en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: Gastric cancer (GC) in younger patients often exhibits aggressive behavior and a poorer prognosis than that in older patients. Although the clinical differences may stem from oncogenic gene variations, it is unclear whether genetic differences exist between these groups. This study compared the genetic profiles of early- and late-onset GC and evaluated their impact on treatment outcomes.
Methods: We analyzed genetic data from 1284 patients with GC in the Japanese nationwide Center for Cancer Genomics and Advanced Therapeutics (C-CAT) database, comparing early-onset (<= 39 years; n = 143) and late-onset (>= 65 years; n = 1141) groups. The influence of TP53 mutations on the time to treatment failure (TTF) with platinum-based chemotherapy and the sensitivity of cancer cells with different TP53 mutation sites to oxaliplatin were assessed in vitro.
Results: Early- and late-onset GC showed distinct genetic profiles, with fewer neoantigen-associated genetic changes observed in early-onset cases. In particular, TP53 has distinct mutation sites; R175H and R273 mutations are more frequent in early- and late-onset GC, respectively. The R175H mutation showed higher sensitivity to oxaliplatin in vitro, consistent with the longer TTF in early-onset patients (17.3 vs. 7.0 months, p = 0.013) when focusing on the patients with TP53 mutations.
Conclusion: Genomic differences, particularly in TP53 mutation sites, between early- and late-onset GC support the need for age-specific treatment strategies. en-copyright= kn-copyright= en-aut-name=KamioTomohiro en-aut-sei=Kamio en-aut-mei=Tomohiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KonoYoshiyasu en-aut-sei=Kono en-aut-mei=Yoshiyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HirosunaKensuke en-aut-sei=Hirosuna en-aut-mei=Kensuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OzatoToshiki en-aut-sei=Ozato en-aut-mei=Toshiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YamamotoHideki en-aut-sei=Yamamoto en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HirasawaAkira en-aut-sei=Hirasawa en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=EnnishiDaisuke en-aut-sei=Ennishi en-aut-mei=Daisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TomidaShuta en-aut-sei=Tomida en-aut-mei=Shuta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=ToyookaShinichi en-aut-sei=Toyooka en-aut-mei=Shinichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=OtsukaMotoyuki en-aut-sei=Otsuka en-aut-mei=Motoyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Gastroenterology and Hepatology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Gastroenterology and Hepatology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Gastroenterology, Okayama University Hospital kn-affil= affil-num=5 en-affil=Department of Clinical Genomic Medicine, Okayama University Hospital kn-affil= affil-num=6 en-affil=Department of Clinical Genomic Medicine, Okayama University Hospital kn-affil= affil-num=7 en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital kn-affil= affil-num=8 en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital kn-affil= affil-num=9 en-affil=Center for Comprehensive Genomic Medicine, Okayama University Hospital kn-affil= affil-num=10 en-affil=Department of Gastroenterology and Hepatology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=comprehensive genomic profiling kn-keyword=comprehensive genomic profiling en-keyword=early-onset gastric cancer kn-keyword=early-onset gastric cancer en-keyword=oxaliplatin kn-keyword=oxaliplatin en-keyword=TP53 kn-keyword=TP53 END start-ver=1.4 cd-journal=joma no-vol=43 cd-vols= no-issue=6 article-no= start-page=1108 end-page=1116 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Spray-drying of polymer solutions across a broad concentration range and the subsequent formation of a few micro- ∼nano-meter sized fibers en-subtitle= kn-subtitle= en-abstract= kn-abstract=Spray drying is a widely utilized technique for the concentration and fine particulation of dried products. This study demonstrated that a versatile spray dryer, equipped with a two-fluid nozzle atomizer, can convert polymer solutions into nanoscale fibers by manipulating the conditions of the polymer solutions. The polymers employed in this research included polyvinylpyrrolidones (Mw 24.5 k to 60 kDa), dextrans (70 k to 450–650 kDa), pullulan, gum Arabic, Eudragit and agar, with methanol and water serving as solvents. Various combinations of polymers and solvents were subjected to spray drying at polymer concentrations ranging from 5 to 1000 g/L. Scanning electron microscopy analyses of the spray-dried samples indicated that the products transitioned from micrometer-sized particles to sub-micrometer fibers in several instances when the polymer concentrations exceeded specific threshold levels. The investigation also explored the relationship between these threshold concentrations and the surface tension and viscosity of the polymer solutions. en-copyright= kn-copyright= en-aut-name=AragaChika en-aut-sei=Araga en-aut-mei=Chika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukushimaKaito en-aut-sei=Fukushima en-aut-mei=Kaito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SatoHaruna en-aut-sei=Sato en-aut-mei=Haruna kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HondaNao en-aut-sei=Honda en-aut-mei=Nao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HasegawaTakato en-aut-sei=Hasegawa en-aut-mei=Takato kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NakasoKoichi en-aut-sei=Nakaso en-aut-mei=Koichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=IshidaNaoyuki en-aut-sei=Ishida en-aut-mei=Naoyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=ImamuraKoreyoshi en-aut-sei=Imamura en-aut-mei=Koreyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=6 en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=7 en-affil=Department of Chemical Engineering and Material Sciences, Faculty of Science and Engineering, Doshisha University kn-affil= affil-num=8 en-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University kn-affil= en-keyword=Sub-micron fiber kn-keyword=Sub-micron fiber en-keyword=spray-drying kn-keyword=spray-drying en-keyword=two fluid nozzle atomizer kn-keyword=two fluid nozzle atomizer en-keyword=polyvinylpyrrolidone kn-keyword=polyvinylpyrrolidone en-keyword=polysaccharide kn-keyword=polysaccharide END start-ver=1.4 cd-journal=joma no-vol=79 cd-vols= no-issue=2 article-no= start-page=93 end-page=100 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202504 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Lower Work Engagement Is Associated with Insomnia, Psychological Distress, and Neck Pain among Junior and Senior High School Teachers in Japan en-subtitle= kn-subtitle= en-abstract= kn-abstract=School teachers are subject to both physical and mental health problems. We examined cross-sectional relationships between work engagement and major health outcomes among junior and senior high school teachers in Japan via a nationwide survey in 2019-2020. A total of 3,160 respondents were included in the analyses (19.9% response rate). Work engagement was assessed with the Utrecht Work Engagement Scale-9 (UWES-9), and we thus divided the teachers into quartiles according to their UWES-9 scores. Based on validated questionnaires, we assessed insomnia, psychological distress, and neck pain as health outcomes. A binomial logistic regression adjusted for age, gender, school type, teacher’s roles, involvement in club activities, division of duties, employment status, and whether they lived with family demonstrated that the teachers with lower UWES-9 scores had higher burdens of insomnia, psychological distress, and neck pain (odds ratios [95% confidence intervals] in 4th vs. 1st quartile, 2.92 (2.34-3.65), 3.70 (2.81-4.88), and 2.12 (1.68-2.68), respectively; all trend p<0.001). There were no significant differences in these associations between full-time and part-time teachers. Our findings indicate that low work engagement may contribute to physical and mental health issues among junior and senior high school teachers, thus providing insights for preventing health problems in this profession. en-copyright= kn-copyright= en-aut-name=TsuchieRina en-aut-sei=Tsuchie en-aut-mei=Rina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukudaMari en-aut-sei=Fukuda en-aut-mei=Mari kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TsumuraHideki en-aut-sei=Tsumura en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KinutaMinako en-aut-sei=Kinuta en-aut-mei=Minako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HisamatsuTakashi en-aut-sei=Hisamatsu en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KandaHideyuki en-aut-sei=Kanda en-aut-mei=Hideyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Public Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Public Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Psychology, Graduate School of Technology, Industrial and Social Sciences, Tokushima University kn-affil= affil-num=4 en-affil=Department of Public Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Public Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Public Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=work engagement kn-keyword=work engagement en-keyword=school teachers kn-keyword=school teachers en-keyword=insomnia kn-keyword=insomnia en-keyword=psychological distress kn-keyword=psychological distress en-keyword=neck pain kn-keyword=neck pain END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=7 article-no= start-page=2221 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Length Estimation of Pneumatic Artificial Muscle with Optical Fiber Sensor Using Machine Learning en-subtitle= kn-subtitle= en-abstract= kn-abstract=A McKibben artificial muscle is a soft actuator driven by air pressure, characterized by its flexibility, lightweight design, and high power-to-weight ratio. We have developed a smart artificial muscle that is capable of sensing its motion. To enable this sensing function, an optical fiber was integrated into the sleeve consisting of multiple fibers and serving as a component of the McKibben artificial muscle. By measuring the macrobending loss of the optical fiber, the length of the smart artificial muscle is expected to be estimated. However, experimental results indicated that the sensor's characteristics depend not only on the length but also on the load and the applied air pressure. This dependency arises because the stress applied to the optical fiber increases, causing microbending loss. In this study, we employed a machine learning model, primarily composed of Long Short-Term Memory (LSTM) neural networks, to estimate the length of the smart artificial muscle. The experimental results demonstrate that the length estimation obtained through machine learning exhibits a smaller error. This suggests that machine learning is a feasible approach to enhancing the length measurement accuracy of the smart artificial muscle. en-copyright= kn-copyright= en-aut-name=NiYilei en-aut-sei=Ni en-aut-mei=Yilei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=WakimotoShuichi en-aut-sei=Wakimoto en-aut-mei=Shuichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TianWeihang en-aut-sei=Tian en-aut-mei=Weihang kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TodaYuichiro en-aut-sei=Toda en-aut-mei=Yuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KandaTakefumi en-aut-sei=Kanda en-aut-mei=Takefumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=YamaguchiDaisuke en-aut-sei=Yamaguchi en-aut-mei=Daisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=6 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= en-keyword=McKibben artificial muscle kn-keyword=McKibben artificial muscle en-keyword=machine learning kn-keyword=machine learning en-keyword=optical fiber kn-keyword=optical fiber en-keyword=motion estimation kn-keyword=motion estimation END start-ver=1.4 cd-journal=joma no-vol=2024 cd-vols= no-issue=12 article-no= start-page=135 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241217 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Elliptic virtual structure constants and generalizations of BCOV-Zinger formula to projective Fano hypersurfaces en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this paper, we propose a method for computing genus 1 Gromov-Witten invariants of Calabi-Yau and Fano projective hypersurfaces using the B-model. Our formalism is applicable to both Calabi-Yau and Fano cases. In the Calabi-Yau case, significant cancellation of terms within our formalism occurs, resulting in an alternative representation of the BCOV-Zinger formula for projective Calabi-Yau hypersurfaces. en-copyright= kn-copyright= en-aut-name=JinzenjiMasao en-aut-sei=Jinzenji en-aut-mei=Masao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KuwataKen en-aut-sei=Kuwata en-aut-mei=Ken kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Department of Mathematics, Okayama University kn-affil= affil-num=2 en-affil=Department of General Education, National Institute of Technology, Kagawa College kn-affil= en-keyword=Nonperturbative Effects kn-keyword=Nonperturbative Effects en-keyword=String Duality kn-keyword=String Duality en-keyword=Topological Field Theories kn-keyword=Topological Field Theories en-keyword=Topological Strings kn-keyword=Topological Strings END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue=1 article-no= start-page=67 end-page=74 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202501 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Locally serially coalescent classes of Lie algebras en-subtitle= kn-subtitle= en-abstract= kn-abstract=We assume that a basic field k has zero characteristic. We show that any Fitting class is serially coalescent for locally finite Lie algebras. We also show that any class X satisfying N ≤ X ≤ ˆGr (e.g. Ft, B, Z, Gr, lN, rN, `e(◁)ˆA, ˆe(◁)ˆA, `Gr) is locally serially coalescent for locally finite Lie algebras, and, for any locally finite Lie algebra L, the X-ser radical of L is locally nilpotent. en-copyright= kn-copyright= en-aut-name=HondaMasanobu en-aut-sei=Honda en-aut-mei=Masanobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SakamotoTakanori en-aut-sei=Sakamoto en-aut-mei=Takanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Medical and Life Sciences kn-affil= affil-num=2 en-affil=Department of Mathematics, University of Teacher Education Fukuoka kn-affil= en-keyword=Lie algebra kn-keyword=Lie algebra en-keyword=serial subalgebra kn-keyword=serial subalgebra en-keyword=locally coalescent class kn-keyword=locally coalescent class END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue=1 article-no= start-page=29 end-page=51 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202501 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The Quillen model structure on the category of diffeological spaces en-subtitle= kn-subtitle= en-abstract= kn-abstract=We construct on the category of diffeological spaces a Quillen model structure having smooth weak homotopy equivalences as the class of weak equivalences. en-copyright= kn-copyright= en-aut-name=HaraguchiTadayuki en-aut-sei=Haraguchi en-aut-mei=Tadayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimakawaKazuhisa en-aut-sei=Shimakawa en-aut-mei=Kazuhisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education for Human Growth, Nara Gakuen University kn-affil= affil-num=2 en-affil=Okayama University kn-affil= en-keyword=Diffeological space kn-keyword=Diffeological space en-keyword=Homotopy theory kn-keyword=Homotopy theory en-keyword=Model category kn-keyword=Model category END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=3 article-no= start-page=033907 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Development of density measurement at high pressure and high temperature using the x-ray absorption method combined with laser-heated diamond anvil cell en-subtitle= kn-subtitle= en-abstract= kn-abstract=The densities of liquid materials at high pressures and high temperatures are important information to understand the elastic behavior of liquids at extreme conditions, which is closely related to the formation and evolution processes of the Earth and planetary interiors. The x-ray absorption method is an effective method to measure the density of non-crystalline materials at high pressures. However, the temperature condition of the x-ray absorption method using a diamond anvil cell (DAC) has been limited to 720 K to date. To significantly expand the measurable temperature condition of this method, in this study, we developed a density measurement technique using the x-ray absorption method in combination with a laser-heated DAC. The density of solid Ni was measured up to 26 GPa and 1800 K using the x-ray absorption method and evaluated by comparison with the density obtained from the x-ray diffraction. The density of solid Ni with a thickness >17 μm was determined with an accuracy of 0.01%–2.2% (0.001–0.20 g/cm3) and a precision of 0.8%–1.8% (0.07–0.16 g/cm3) in the x-ray absorption method. The density of liquid Ni was also determined to be 8.70 ± 0.15–8.98 ± 0.38 g/cm3 at 16–23 GPa and 2230–2480 K. Consequently, the temperature limit of the x-ray absorption method can be expanded from 720 to 2480 K by combining it with a laser-heated DAC in this study. en-copyright= kn-copyright= en-aut-name=TerasakiHidenori en-aut-sei=Terasaki en-aut-mei=Hidenori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KaminaHiroyuki en-aut-sei=Kamina en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KawaguchiSaori I. en-aut-sei=Kawaguchi en-aut-mei=Saori I. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KondoTadashi en-aut-sei=Kondo en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MoriokaKo en-aut-sei=Morioka en-aut-mei=Ko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TsuruokaRyo en-aut-sei=Tsuruoka en-aut-mei=Ryo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SakuraiMoe en-aut-sei=Sakurai en-aut-mei=Moe kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=YonedaAkira en-aut-sei=Yoneda en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KamadaSeiji en-aut-sei=Kamada en-aut-mei=Seiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=HiraoNaohisa en-aut-sei=Hirao en-aut-mei=Naohisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Earth Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Earth Sciences, Okayama University kn-affil= affil-num=3 en-affil=Japan Synchrotron Radiation Research Institute, SPring-8 kn-affil= affil-num=4 en-affil=Department of Earth and Space Science, Osaka University kn-affil= affil-num=5 en-affil=Department of Earth Sciences, Okayama University kn-affil= affil-num=6 en-affil=Department of Earth and Space Science, Osaka University kn-affil= affil-num=7 en-affil=Department of Earth Sciences, Okayama University kn-affil= affil-num=8 en-affil=Department of Earth and Space Science, Osaka University kn-affil= affil-num=9 en-affil=AD Science Incorporation kn-affil= affil-num=10 en-affil=Japan Synchrotron Radiation Research Institute, SPring-8 kn-affil= END start-ver=1.4 cd-journal=joma no-vol=26 cd-vols= no-issue=6 article-no= start-page=2485 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250311 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Vesicular Glutamate Transporter 3 Is Involved in Glutamatergic Signalling in Podocytes en-subtitle= kn-subtitle= en-abstract= kn-abstract=Glomerular podocytes act as a part of the filtration barrier in the kidney. The activity of this filter is regulated by ionotropic and metabotropic glutamate receptors. Adjacent podocytes can potentially release glutamate into the intercellular space; however, little is known about how podocytes release glutamate. Here, we demonstrated vesicular glutamate transporter 3 (VGLUT3)-dependent glutamate release from podocytes. Immunofluorescence analysis revealed that rat glomerular podocytes and an immortal mouse podocyte cell line (MPC) express VGLUT1 and VGLUT3. Consistent with this finding, quantitative RT-PCR revealed the expression of VGLUT1 and VGLUT3 mRNA in undifferentiated and differentiated MPCs. In addition, the exocytotic proteins vesicle-associated membrane protein 2, synapsin 1, and synaptophysin 1 were present in punctate patterns and colocalized with VGLUT3 in MPCs. Interestingly, approximately 30% of VGLUT3 colocalized with VGLUT1. By immunoelectron microscopy, VGLUT3 was often observed around clear vesicle-like structures in differentiated MPCs. Differentiated MPCs released glutamate following depolarization with high potassium levels and after stimulation with the muscarinic agonist pilocarpine. The depletion of VGLUT3 in MPCs by RNA interference reduced depolarization-dependent glutamate release. These results strongly suggest that VGLUT3 is involved in glutamatergic signalling in podocytes and may be a new drug target for various kidney diseases. en-copyright= kn-copyright= en-aut-name=NishiiNaoko en-aut-sei=Nishii en-aut-mei=Naoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KawaiTomoko en-aut-sei=Kawai en-aut-mei=Tomoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YasuokaHiroki en-aut-sei=Yasuoka en-aut-mei=Hiroki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AbeTadashi en-aut-sei=Abe en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TatsumiNanami en-aut-sei=Tatsumi en-aut-mei=Nanami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HaradaYuika en-aut-sei=Harada en-aut-mei=Yuika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MiyajiTakaaki en-aut-sei=Miyaji en-aut-mei=Takaaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=LiShunai en-aut-sei=Li en-aut-mei=Shunai kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=TsukanoMoemi en-aut-sei=Tsukano en-aut-mei=Moemi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=WatanabeMasami en-aut-sei=Watanabe en-aut-mei=Masami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=OgawaDaisuke en-aut-sei=Ogawa en-aut-mei=Daisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=WadaJun en-aut-sei=Wada en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=TakeiKohji en-aut-sei=Takei en-aut-mei=Kohji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=YamadaHiroshi en-aut-sei=Yamada en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= affil-num=1 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Cell Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Neuroscience, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Neuroscience, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Neuroscience, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Genomics and Proteomics, Advanced Science Research Center, Okayama University kn-affil= affil-num=7 en-affil=Department of Genomics and Proteomics, Advanced Science Research Center, Okayama University kn-affil= affil-num=8 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital kn-affil= affil-num=9 en-affil=Central Research Laboratory, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=10 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital kn-affil= affil-num=11 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=12 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=13 en-affil=Department of Neuroscience, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=14 en-affil=Department of Neuroscience, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=VGLUT3 kn-keyword=VGLUT3 en-keyword=glutamate kn-keyword=glutamate en-keyword=podocyte kn-keyword=podocyte en-keyword=glutamatergic transmission kn-keyword=glutamatergic transmission END start-ver=1.4 cd-journal=joma no-vol=82 cd-vols= no-issue= article-no= start-page=101 end-page=112 dt-received= dt-revised= dt-accepted= dt-pub-year=1989 dt-pub=19891115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Some Sketches of Social Networks in Canberra kn-title=キャンベラの社会的ネットワークについて ――参与観察の記録―― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=83 cd-vols= no-issue= article-no= start-page=155 end-page=164 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19900315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Stages of Development in Canberra―PART I kn-title=キャンベラにおける開発の諸段階（Ⅰ） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=84 cd-vols= no-issue= article-no= start-page=165 end-page=177 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19900716 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Stages of Development in Canberra―Part II kn-title=キャンベラにおける開発の諸段階（Ⅱ） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=87 cd-vols= no-issue= article-no= start-page=63 end-page=83 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19910715 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Daily Social Support among Canberra Residents kn-title=日常生活における援助希求行動 ―キャンベラの事例― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　This paper reports a study that investigated perceived sources of daily support. To gather empirical evidence, a sample survey of women in four study areas of Canberra was conducted in 1986-1987. Three hundred and ninety-four women who were under 55 years of age and who were married or in a de facto relationship were interviewed. They responded to six hypothetical difficult situations by identifying the first source from which they would seek support. Analysis of the data has revealed the following ;
　(1) When respondents had their relatives in Canberra, they regarded their relatives as the chief source of daily support. However, there were many residents without local relatives in Canberra. For such respondents, their relatives were not so helpful in daily support. Incidentally, workmates were thought of as much less important providers of support than relatives, neighbours or friends.
　(2) Social networks were differentiated in that respondents tended to depend on types of people appropriate to individual difficult situations.
　(3) Dependable friends and workmates tended to live closer than dependable relatives.
　(4) Dependable relatives were usually limited to immediate family, such as parents (-in-law), brothers (-in-law) or sisters (-in-law). en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=88 cd-vols= no-issue= article-no= start-page=11 end-page=27 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19911115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Variations of Residential Groups in Okayama City, Japan kn-title=地方都市における町内会の類型 ――岡山市の事例―― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=89 cd-vols= no-issue= article-no= start-page=7 end-page=34 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19920316 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The First Report on the Changing Rural Community Survey―Part 1 kn-title=「混住化農村調査」第１次報告書(1) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue= article-no= start-page=9 end-page=15 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19920715 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The First Report on the Changing Rural Community Survey――Part II kn-title=「混住化農村調査」第１次報告書（Ⅱ） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue= article-no= start-page=9 end-page=18 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19921116 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Occupational Change in Australia 1961-86 kn-title=オーストラリアにおける職業構造の趨勢分析 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=92 cd-vols= no-issue= article-no= start-page=9 end-page=24 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Some Features of Canberra　――Part I kn-title=キャンベラの概説(1) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue= article-no= start-page=219 end-page=236 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930715 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Some Features of Canberra――Part II kn-title=キャンベラの概説(2) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue= article-no= start-page=107 end-page=121 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19931115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Some Remarks on Social Networks in Canberra kn-title=キャンベラにおける社会的ネットワークの一考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=95 cd-vols= no-issue= article-no= start-page=141 end-page=152 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on the Migration Process into a Changing Rural - urban Fringe Community kn-title=混住化農村への流入過程の一考察 一倉敷市上東における既婚女性の事例一 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue= article-no= start-page=143 end-page=144 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19941115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Note on the Occupational Classification kn-title=職業分類についてのノート en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue= article-no= start-page=55 end-page=69 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19950315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Research Note on Okayama City, Japan kn-title=岡山市についての研究ノート en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=100 cd-vols= no-issue= article-no= start-page=87 end-page=90 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19951115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Meaning of Studying Canberra kn-title=キャンベラ研究の意義について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=101 cd-vols= no-issue= article-no= start-page=41 end-page=55 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on the Effect of Residential Mobility on Social Networks kn-title=地理的移動が社会的ネットワークに及ぼす効果の研究 ——キャンベラにおける検証—— en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMASAO en-aut-sei=NOBE en-aut-mei=MASAO kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=107 cd-vols= no-issue= article-no= start-page=195 end-page=197 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980313 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Consideration on Canberra kn-title=キャンベラについての一考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　キャンベラの住民が住環境を高く評価していることを指摘し，キャンベラの首都建設が日本の首都機能移転にどのようなことを示唆するかを議論した。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=キャンベラ kn-keyword=キャンベラ en-keyword=首都機能移転 kn-keyword=首都機能移転 en-keyword=住環境評価 kn-keyword=住環境評価 END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue= article-no= start-page=141 end-page=152 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980715 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Research Note on Takahashi City, Japan kn-title=高梁市についての研究ノート en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教室 en-keyword=高梁市 (Takahashi City) kn-keyword=高梁市 (Takahashi City) en-keyword=人口動態 (Population Decrease and Migration of Population) kn-keyword=人口動態 (Population Decrease and Migration of Population) en-keyword=人口の空間構造 (Spatial Distribution of Population) kn-keyword=人口の空間構造 (Spatial Distribution of Population) en-keyword=就業者の構成 (Workforce Structure) kn-keyword=就業者の構成 (Workforce Structure) END start-ver=1.4 cd-journal=joma no-vol=109 cd-vols= no-issue= article-no= start-page=115 end-page=130 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19981113 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Student Evaluation of a Revised Course of Sociology Lectures in the Liberal-arts Education kn-title=一般科目「社会学」の授業の改善と学生による授業評価について en-subtitle= kn-subtitle= en-abstract= kn-abstract=　私は平成10年度の前期に一般科目（一般教養科目）の「社会学」の授業を担当した。本稿では，受講学生の授業評価などにより，その授業を検討し，次の3点を明らかにした。(1)私は，映画やドキュメンタリーを上映したり「講義ノート」を配布することで，社会学の授業を理解しやすくするように努めた。また，書評レポートを学生に書かせ論文作成の基礎を学ばせようとした。学生は，これらの授業改善をかなり評価していた。それから，授業のやり方や講義内容でとりたてて問題点はなかった。(2)多くの学生は，映画を上映したとき，授業時間が延長になることに苦情を持っていた。私は学生があげた苦情を解決しようと授業中に努力したが，大部分の苦情は私の努力ではどうにもできないものであった。(3)大学の当局や事務担当者には，次の2つが望まれる。第1に， 2時限連続の授業を設けることができるようにするなど，授業の性格に応じてより柔軟に，授業を開講できるようすべきだ。もしこれが可能であれば，私の授業に対する学生の苦情はほとんどなかった。第2に，シラバスを全学部の学生に配布するとか，インターネットで誰でも簡単に閲覧できるようにすべきだ。
　次に，授業の改善として，私は次の3点を提案した。(1)研究の方法を一般教育課程で学生に組織的に教えること。(2)大学の授業を他の教官に公開することによって，授業の改善に努めること。(3)教官の授業負担を軽減し，授業の充実をはかること。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=社会学 kn-keyword=社会学 en-keyword=授業改善 kn-keyword=授業改善 en-keyword=授業評価 kn-keyword=授業評価 END start-ver=1.4 cd-journal=joma no-vol=110 cd-vols= no-issue= article-no= start-page=121 end-page=129 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Student Evaluation of a Revised Course of Sociology Lectures in the Professional Education kn-title=専門科目「社会学A」の授業の改善と学生による授業評価について en-subtitle= kn-subtitle= en-abstract= kn-abstract=　私は平成10年度の前期に教育学部の専門科目である「社会学A」の授業を担当した。本稿では，受講学生の授業評価により，その授業を検討し，次の3点を明らかにした。(1)私は，映画やドキュメンタリーを上映したり「講義ノート」を配布することで，社会学の授業を理解しやすくするように努めた。また，書評レポートを学生に書かせ論文作成の基礎を学ばせようとした，学生は，これらの授業改善をかなり評価していた。また，学生は授業での話し方や講義内容も好意的に評価していた。逆に，悪かった点は，授業の補講を土曜日の1日に集中して実施したことであった。これ以外では， とくに悪い点は指摘されなかった。その結果，学生は86.2点と比較的高めに私の授業を採点した。(2)書評レポートを学生に課すとき，その見本を学生に配布すると，書評レポートの質が大幅に向上する。(3)学生は私の授業を好意的にとらえていたけれど，受講学生数は少なかった。これから，受講学生数は主に授業の単位取得が容易かどうかによって決まってしまうと考えられる。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=社会学 kn-keyword=社会学 en-keyword=専門科目 kn-keyword=専門科目 en-keyword=授業改善 kn-keyword=授業改善 en-keyword=授業評価 kn-keyword=授業評価 END start-ver=1.4 cd-journal=joma no-vol=111 cd-vols= no-issue= article-no= start-page=75 end-page=85 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990715 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Indonesian Immigrants in Melbourne kn-title=メルボルンにおけるインドネシア移民 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿では，参与観察によってメルボルンに住むインドネシア人の生活を解明した。明らかになったのは，次の9点である。(1)インドネシア人はメルボルンの中で分散して住んでいる。(2)インドネシア人の教会は親睦集団としての性格が強い。社会階層による対立が教会のメンバーの中に見られる。(3)メルボルンに住むインドネシア人は宗教によって分断されている。(4)夫婦共働きの増加と自家用車の普及によって，近隣関係がだんだんと希薄になっている。(5)窃盗の増加に対抗するため，住民は「ネイバーフッド・ウォッチ」という防犯のための相互協力組織を結成した。しかし，その活動はあまり活発でない。(6)参与観察をしたインドネシア移民の女性は，近隣地域であまり社会関係を持っておらず，メルボルンのさまざまな場所で友人関係を組織していた。また，大部分の友人関係はインドネシア人と取り結んでいた。(7)インドネシア移民の子供は家庭と学校のしつけが異なるから，混乱をしてしまう。(8)インドネシア移民は日常生活で差別されていると感じている。(9)移民のオーストラリアでの職業的地位はたいてい本国でのそれよりも低い。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=メルボルン kn-keyword=メルボルン en-keyword=インドネシア移民 kn-keyword=インドネシア移民 en-keyword=参与観察 kn-keyword=参与観察 END start-ver=1.4 cd-journal=joma no-vol=112 cd-vols= no-issue= article-no= start-page=57 end-page=78 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19991115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Elderly Women's Personal Networks and Subjective Well-being in Takahashi City, Japan: Initial Findings kn-title=「高梁市高齢女性のパーソナル・ネットワークと 主観的幸福感調査」の基礎分析 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　筆者は，平成9年から平成10年にかけて高齢女性を対象に岡山県高梁市において集団加入やパーソナル・ネットワークに関する調査を実施した。本稿では，この調査の概要を説明し，単純集計表を提示した。そして，このデータを用いて，高梁市への流入過程，身体的健康，身体的活動能力，モラール，生活満足度，各種の集団への加入，町内会などがおこなう活動への参加，パーソナル・ネットワークについて検討をおこなった。さて，高梁市は都市部（＝市街地）と農村部からなりたっているが，都市部と農村部で暮らす高齢女性の違いについても考察した。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=高齢女性 kn-keyword=高齢女性 en-keyword=パーソナル・ネットワーク kn-keyword=パーソナル・ネットワーク en-keyword=主観的幸福感 kn-keyword=主観的幸福感 en-keyword=集団加入 kn-keyword=集団加入 END start-ver=1.4 cd-journal=joma no-vol=113 cd-vols= no-issue= article-no= start-page=69 end-page=85 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Life Styles of Elderly Women in the Highlands of Takahashi City, Japan kn-title=高梁市の高原部に住む高齢女性の暮らし en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿では，まず，過疎化と高齢化が岡山県高梁市を構成する各地区でどのくらい進行しているかを国勢調査のデータによって明らかにした。次に，箪者が1999年4月から5月にかけて高梁市で聞き取り調査をおこなったが，この調査によって収集した事例のうちから4つの事例を提示した。これを検討することによって，同市の高原部に住む高齢女性がどのような暮らしをしているかを明らかにした。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=高梁市 kn-keyword=高梁市 en-keyword=吉備高原 kn-keyword=吉備高原 en-keyword=高齢女性 kn-keyword=高齢女性 en-keyword=過疎化 kn-keyword=過疎化 en-keyword=高齢化 kn-keyword=高齢化 END start-ver=1.4 cd-journal=joma no-vol=114 cd-vols= no-issue= article-no= start-page=47 end-page=57 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000717 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Life Styles of Solitary Elderly Women in the Highlands of Takahashi City, Japan kn-title=高梁市の高原部に住む一人暮らしの高齢女性の生活 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　筆者は2000年2月に高梁市の高原部に住む一人暮らしの高齢女性に聞き取り調査をおこなった。本稿では，収集した事例のうちから3つの事例を提示し，これを検討することによって，一人暮らしの高齢女性がどのような暮らしをしているかを明らかにした。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=高梁市 kn-keyword=高梁市 en-keyword=吉備高原 kn-keyword=吉備高原 en-keyword=高齢女性 kn-keyword=高齢女性 en-keyword=過疎化 kn-keyword=過疎化 en-keyword=高齢化 kn-keyword=高齢化 END start-ver=1.4 cd-journal=joma no-vol=115 cd-vols= no-issue= article-no= start-page=29 end-page=55 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20001115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Women's Personal Networks in Melbourne: Initial Findings kn-title=「メルボルンに居住する女性のパーソナル・ネットワーク調査」の基礎分析 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　筆者は，1999年8月から9月にかけて20歳以上55歳以下の女性を対象にメルボルンの2つの中産階層地域において集団加入やパーソナル・ネットワークに関する調査を実施した。本稿では，この調査の概要を説明し，単純集計表を提示した。そして，このデータを用いて，メルボルンヘの流入過程，各種の集団への加入，パーソナル・ネットワークについて検討をおこなった。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教室 en-keyword=メルボルン kn-keyword=メルボルン en-keyword=女性 kn-keyword=女性 en-keyword=パーソナル・ネットワーク kn-keyword=パーソナル・ネットワーク en-keyword=集団加入 kn-keyword=集団加入 END start-ver=1.4 cd-journal=joma no-vol=116 cd-vols= no-issue= article-no= start-page=43 end-page=53 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Life Styles of Elderly Women in the Urban Areas of Takahashi City, Japan-Part 1 kn-title=高梁市の市街地に住む高齢女性の暮らし（その１) en-subtitle= kn-subtitle= en-abstract= kn-abstract=　筆者は2000年10月から11月にかけて高梁市の市街地に住む高齢女性に聞き取り調査をおこなった。本稿では，収集した事例のうちから６つの事例を提示し，これを検討することによって，地方小都市の市街地に住む高齢女性がどのような暮らしをしているかを明らかにした。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=高梁市 kn-keyword=高梁市 en-keyword=市街地 kn-keyword=市街地 en-keyword=高齢女性 kn-keyword=高齢女性 en-keyword=高齢化 kn-keyword=高齢化 END start-ver=1.4 cd-journal=joma no-vol=117 cd-vols= no-issue= article-no= start-page=35 end-page=41 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010715 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Life Styles of Elderly Women in the Urban Areas of Takahashi City, Japan-PartII kn-title=高梁市の市街地に住む高齢女性の暮らし（その２） en-subtitle= kn-subtitle= en-abstract= kn-abstract=　筆者は2000年10月から11月にかけて高梁市の市街地に住む高齢女性に聞き取り調査をおこなった。本稿では，収集した事例のうちから６つの事例を提示し，これを検討することによって，地方小都市の市街地に住む高齢女性がどのような暮らしをしているかを明らかにした。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=高梁市 kn-keyword=高梁市 en-keyword=市街地 kn-keyword=市街地 en-keyword=高齢女性 kn-keyword=高齢女性 en-keyword=高齢化 kn-keyword=高齢化 END start-ver=1.4 cd-journal=joma no-vol=118 cd-vols= no-issue= article-no= start-page=31 end-page=37 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20011115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Basic Characteristics of Personal Networks of Elderly Women in a Small Japanese City kn-title=地方小都市に住む高齢女性のパーソナル・ネットワークの基本的特徴 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　筆者は1997年11月から1998年1月にかけて高梁市に住む高齢女性に面接調査をおこなった。本稿では，そのデータを分析することによって，①パーソナル・ネットワークの規模，②その構成，③性別と年齢での社会関係の同質性，④ソーシャル・サポートの入手を検討した。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=高梁市 kn-keyword=高梁市 en-keyword=高齢女性 kn-keyword=高齢女性 en-keyword=パーソナル・ネットワーク kn-keyword=パーソナル・ネットワーク en-keyword=ソーシャル・サボート kn-keyword=ソーシャル・サボート END start-ver=1.4 cd-journal=joma no-vol=120 cd-vols= no-issue= article-no= start-page=23 end-page=30 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020715 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effects of income on personal networks of elderly women in a small local city kn-title=収入と地方小都市に住む高齢女性のパーソナル・ネットワーク en-subtitle= kn-subtitle= en-abstract= kn-abstract=　地方小都市である岡山県高梁市で65歳以上80歳未満の高齢女性を対象に1997年から1998年にかけて調査をおこなった。本稿では，重回帰分析によってそのデータを分析し，収入が高齢女性のパーソナル・ネットワークに与える影響を分析した。そして，次の3点を明らかにした。①収入が高い高齢女性ほど多くの親族関係と友人関係を組織し，家族の外で多くの社会関係を保持していた。しかし，収入は近隣関係数に影響を及ぽしてはいなかった。②居住場所は栽族関係数と近隣関係数に有意な影響を及ぽしていたけれど，友人関係数には影響を与えてはいなかった。これは，フィッシャーの下位文化理論が地方小都市に住む高齢女性の友人関係には妥当しないことを示唆している。③収入は，家族外の社会関係総数に最も強い影響力を持っていた。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=パーソナル・ネットワーク kn-keyword=パーソナル・ネットワーク en-keyword=高齢女性 kn-keyword=高齢女性 en-keyword=地方小都市 kn-keyword=地方小都市 en-keyword=下位文化理論 kn-keyword=下位文化理論 END start-ver=1.4 cd-journal=joma no-vol=59 cd-vols= no-issue= article-no= start-page=25 end-page=44 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on the Relationship between Kazuo Inamori's Philosophy, the Teachings of Nanshu Saigo, and the Iroha Poem by Prince Jisshin kn-title=稲盛和夫のフィロソフィーと西郷南洲翁遺訓及び日新公いろは歌の連関についての考察 en-subtitle= kn-subtitle= en-abstract=Kazuo Inamori is a rare business leader who founded DDI, the predecessor of Kyocera and KDDI, in one generation, and grew it into a trillion-yen company. He also rebuilt the bankrupt Japan Airlines (JAL) in three years and led it to relisting. He has not only led tens of thousands of people with his unique management method called amoeba management, but also with management principles. What are the roots of the way of life that a manager of a small and medium-sized business has derived from management? What is the Goju education that is the foundation of Satsuma, where he was born and raised? From the perspective of business management, it is interesting to know what it is like.
How is it related to Saigo Nanshu Ikun, the record of the words and deeds of Saigo Takamori, a local hero whom Kazuo Inamori met after founding Kyocera and used as the basis of his own management philosophy, and Shimazu Nisshin Iroha Uta, left by Shimazu Tadayoshi (Nissin), the father of Shimazu Takahisa, the 15th lord of the Shimazu clan who unified southern Kyushu, including Satsuma and Hyuga, in the 16th century? First of all, I am interested in the relationship between the ideas of the three men born in Satsuma. In this study, we used the grounded theory approach, a qualitative research method, to analyze the correlation between Kazuo Inamori's philosophy, the teachings of Nanshu Saigo, and the Nisshin Iroha Uta. As a result, the analysis revealed that the three concepts are related across 400 years of time. In particular, Kazuo Inamori's philosophy is not only positively influenced by the teachings of Nanshu Saigo, which are the words and deeds of Takamori Saigo, whom Kazuo Inamori admires, but also by the Nisshin Iroha Uta, which dates back 400 years, due to his education in Satsuma. It is believed that the ideals that the people of Satsuma have inherited for 400 years contain concepts that should be the foundation for people's lives, or that should be important core ideas and qualities in life, regardless of the era. kn-abstract=　一代で京セラやKDDIの前身となる第二電電（DDI）を創業し、合計数兆円企業に育て、倒産した日本航空（JAL）を3年で再建し、再上場に導いた稀代の経営者稲盛和夫は、アメーバ経営という独自の経営手法だけでなく、理念経営により数万人を導いてきた。中小企業の一経営者が経営の中から導き出した人生成功の処世術のルーツは何処にあるのか。生まれ育った薩摩の基礎となる郷中（ごじゅう）教育とは何か、などについて経営学の観点から関心が湧く。
　稲盛和夫が京セラ創業以降に出会い、自ら経営理念の基礎とした地元の偉人である西郷隆盛の言行録である西郷南洲翁遺訓及び16世紀に薩摩や日向など南九州を統一した島津家第15代領主島津貴久公の実父島津忠良（日新）が残した、島津日新公いろは歌とどのように連関があるのか。そもそも薩摩生まれの3名の思想にどのような連関があるのか、についても関心が湧く。この研究では、質的研究法であるグラウンデッド・セオリー・アプローチを援用して、稲盛和夫のフィロソフィーと西郷南洲翁遺訓及び日新公いろは歌の連関について分析した。結果的に3つの概念は400年の時代を超えて、連関していることが分析により明らかになった。特に稲盛和夫のフィロソフィーが稲盛和夫が敬愛する西郷隆盛の言行録である西郷南洲翁遺訓に正の影響を受けているだけでなく、薩摩での教育を背景に、400年前に遡る日新公いろは歌からも正の影響を受けていることが明らかになった。400年に渡り薩摩の人々が受け継いできた理念には、時代を超えても人が生きていく中で基礎とすべき、もしくは人生で重要なコアな思想・資質とすべき概念があると考えられる。 en-copyright= kn-copyright= en-aut-name=MACHIDAHisashi en-aut-sei=MACHIDA en-aut-mei=Hisashi kn-aut-name=町田尚史 kn-aut-sei=町田 kn-aut-mei=尚史 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学教育推進機構 en-keyword=稲盛和夫 (Kazuo Inamori) kn-keyword=稲盛和夫 (Kazuo Inamori) en-keyword=フィロソフィー (philosophy) kn-keyword=フィロソフィー (philosophy) en-keyword=西郷隆盛 (Takamori Saigo) kn-keyword=西郷隆盛 (Takamori Saigo) en-keyword=西郷南洲翁遺訓 (the teachings of Nanshu Saigo) kn-keyword=西郷南洲翁遺訓 (the teachings of Nanshu Saigo) en-keyword=島津忠良（日新） (Tadayoshi Shimazu (Nissin)) kn-keyword=島津忠良（日新） (Tadayoshi Shimazu (Nissin)) en-keyword=日新公いろは歌 (Nisshin Iroha Uta) kn-keyword=日新公いろは歌 (Nisshin Iroha Uta) en-keyword=グラウンデッド・セオリー・アプローチ (grounded theory approach) kn-keyword=グラウンデッド・セオリー・アプローチ (grounded theory approach) END start-ver=1.4 cd-journal=joma no-vol=39 cd-vols= no-issue= article-no= start-page=(1) end-page=(16) dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250320 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=髙階杞一「風の五線譜」の解釈 ―発音から詩の構造を読み解く― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=又吉里美 kn-aut-sei=又吉 kn-aut-mei=里美 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue= article-no= start-page=207 end-page=214 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20021115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Basic Characteristics of Personal Networks of Elderly Women in a Small Japanese City kn-title=メルボルンの住民の暮らし 一参与観察による研究一 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　メルボルンに住むオーストラリア人の家庭でホームステイをおこない，その家族生活や交際を参与観察した。そして，次の2点を明らかにした。①メルボルンでは，大人は1台ずつ車を持つことが一般的になってきた。外出にはたいてい車を使い，近所を歩くことが少なくなったから，近所の人々と知り合いになりにくくなった。そこで，近隣関係や近隣交際が乏しくなり，近所の人々と助けあうこともあまりなくなった。②車を使って外出をするので，自由に行き来できる地理的範囲が広くなった。そのため，住民は広範囲に住む多くの人々の中から，気心があったり，利害や関心を共有する相手を自由に選んで友人関係を取り結び，そうした友人と交遊をしたり，生活の助け合いをおこなっている。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=メルボルン kn-keyword=メルボルン en-keyword=参与観察 kn-keyword=参与観察 en-keyword=パーソナル・ネットワーク kn-keyword=パーソナル・ネットワーク en-keyword=ソーシャル・サポート kn-keyword=ソーシャル・サポート END start-ver=1.4 cd-journal=joma no-vol=123 cd-vols= no-issue= article-no= start-page=219 end-page=227 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=20030710 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Trend Analysis of Migration in a Small Local Japanese City kn-title=地方小都市における人口の地理的移動の趨勢分析 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　高梁市は，岡山県の中西部に位置する地方小都市である。本稿では，1965年，1975年，1985年，1995年，2000年における，高梁市の人口の地理的移動に関するデータを検討しその趨勢を明らかにした。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=地理的移動 kn-keyword=地理的移動 en-keyword=転入・転出 kn-keyword=転入・転出 en-keyword=純移動数 kn-keyword=純移動数 en-keyword=地方小都市 kn-keyword=地方小都市 END start-ver=1.4 cd-journal=joma no-vol=124 cd-vols= no-issue= article-no= start-page=113 end-page=121 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=20031115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Trend Analysis of Migration in Okayama City, Japan kn-title=岡山市における人口の地理的移動の趨勢分析 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　岡山市は，人口約63万人の地方中核都市である。本稿では，1965年，1975年，1985年，1995年，2000年における，岡山市のデータを検討し，人口の地理的移動の趨勢を明らかにした。さらに，岡山県の地方小都市である高梁市の地理的移動と比較をおこなった。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=地理的移動 kn-keyword=地理的移動 en-keyword=転入・転出 kn-keyword=転入・転出 en-keyword=純移動数 kn-keyword=純移動数 en-keyword=岡山市 kn-keyword=岡山市 END start-ver=1.4 cd-journal=joma no-vol=125 cd-vols= no-issue= article-no= start-page=107 end-page=110 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040310 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Research Note on Aged Care Services in Melbourne kn-title=メルボルンにおける高齢者へのケア・サービスと介護サービス en-subtitle= kn-subtitle= en-abstract= kn-abstract=　筆者はメルボルン大都市圏にあるホワイトホース市で市役所の福祉担当者や教会が運営するナーシング・ホームを訪問し，高齢者へのケア・サービスや介護サービスに関しての聞き取り調査や資料収集をおこなった。本稿では，その聞き取り調査や収集した資料にもとづいて，同市におけるケア・サービスと介護サービスの現状を紹介した。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=キメルボルン kn-keyword=キメルボルン en-keyword=高齢者 kn-keyword=高齢者 en-keyword=ケア・サービス kn-keyword=ケア・サービス en-keyword=介護サービス kn-keyword=介護サービス END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=裏表紙・英文目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=奥付 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=岡山大学教師教育開発センター紀要原稿執筆要領 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=岡山大学教師教育開発センターの活動状況の概要 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=357 end-page=371 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Proposals for Supporting Children’s Adaptation in School Mergers and Closures kn-title=学校統廃合における児童の適応支援策の提言 en-subtitle= kn-subtitle= en-abstract=The purpose of this study is to examine the impact of school mergers and closures on children through a literature review and field survey and to propose strategies for supporting children's adaptation to the resulting environmental transitions. First, a literature review on school mergers and closures indicated that such experiences could influence children's later interpersonal relationships and increase stress responses. However, research on the impact of school mergers and closures on children remains limited, with insufficient understanding of their psychological effects on children. Next, interviews conducted as part of a field survey revealed that school mergers and closures could be significant sources of stress for children. Based on these findings, we recommends multi-level support measures targeting individuals, classes, grades, and entire schools, primarily through special activities, to help mitigate the impact of these transitions on children. kn-abstract=本研究の目的は，学校統廃合に係る文献検索および実態調査を通して，学校統廃合という環境移行が児童に与える影響について検討し，学校統廃合がもたらす環境移行に対する児童の適応支援策について提言することである。まず，学校統廃合に係る文献検索を行った結果，学校統廃合の経験が児童生徒のその後の人間関係形成やストレス反応の増加に影響を与えている可能性が示された。しかし，学校統廃合が児童に与える影響に関する研究は非常に少なく，統廃合の経験が児童に与える心理的影響については十分に解明されていないことがわかった。次に，実態調査として行ったインタビューにおいて，学校統廃合が児童にとって大きなストレス要因となる可能性があることがわかった。これらの現状を踏まえて，学校統廃合が児童に与える影響を和らげるため，特別活動を中心として，個人・学級・学年・学校レベルでの具体的な取組を提案した。 en-copyright= kn-copyright= en-aut-name=IKEDAYuka en-aut-sei=IKEDA en-aut-mei=Yuka kn-aut-name=池田祐加 kn-aut-sei=池田 kn-aut-mei=祐加 aut-affil-num=1 ORCID= en-aut-name=IZUMITsuguyuki en-aut-sei=IZUMI en-aut-mei=Tsuguyuki kn-aut-name=伊住継行 kn-aut-sei=伊住 kn-aut-mei=継行 aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Education (Professional Degree Corse), Okayama University kn-affil=岡山大学大学院教育学研究科大学院生 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=学校統廃合 (School Consolidation) kn-keyword=学校統廃合 (School Consolidation) en-keyword=児童 (Children) kn-keyword=児童 (Children) en-keyword=人間関係形成 (Relationship Building) kn-keyword=人間関係形成 (Relationship Building) en-keyword=ストレス (Stress) kn-keyword=ストレス (Stress) en-keyword=特別活動 (Special Activities) kn-keyword=特別活動 (Special Activities) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=341 end-page=355 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Research Trends on Educational Needs and Support of Children with Cancer kn-title=小児がん患児に対する教育的支援とその研究動向 en-subtitle= kn-subtitle= en-abstract=　In this study, we summarized research trends related to the educational needs and support of children with cancer from the perspectives of “learning,” “self-management,” “interpersonal,” “psychological,” and “collaboration,”. In terms of learning, the study showed that experiential learning and distance education are solutions to the problem of delayed learning due to prolonged absence from school and poor concentration during treatment. Next, in self-management, it is important to educate affected children so that they can fully understand the disease and treatment. In addition, in terms of interpersonal support, it is difficult for the affected patients to build relationships with friends, but providing opportunities for interaction is expected to contribute to the improvement of interpersonal relationships. In terms of psychological support, the anxiety associated with treatment is a major psychological burden for the affected children, and the understanding of their friends and the intervention of university student volunteers are effective in helping them achieve psychological stability. Finally, the lack of cooperation between medical institutions and schools was highlighted as a deficiency in the support system, which needs to be strengthened. In the future, these support measures should be empirically verified to establish a sustainable support system. kn-abstract=　本研究は、小児がん患児の教育的支援に関する研究の動向を明らかにし、今後の課題とその解決策を提起することを目的とした。「学習」、「自己管理」、「対人」、「心理」、「連携」の5つの視点から分析を行った。学習支援について、治療に伴う学習の遅れや集中力の低下に対し、個別の教育支援計画や体験的な学習、および遠隔教育の実施に期待されていた。自己管理支援では、患児が自身の病状や治療による副作用を理解し、自立的に管理できる能力を育成することが求められていた。対人支援について、患児の長期入院により、友人関係の構築が困難になり、入院中や復学後のコミュニケーションの支援が重要であることが確認された。心理支援においては、周囲への効果的ながん教育や大学生ボランティアによる支援が、患児の心理的安定を促すことが示された。最後に、学校と医療機関、保護者の連携不足が指摘されており、連携ツールの開発が求められている。 en-copyright= kn-copyright= en-aut-name=CHENYiwen en-aut-sei=CHEN en-aut-mei=Yiwen kn-aut-name=陳依文 kn-aut-sei=陳 kn-aut-mei=依文 aut-affil-num=1 ORCID= en-aut-name=YOSHITOSHIMunehisa en-aut-sei=YOSHITOSHI en-aut-mei=Munehisa kn-aut-name=吉利宗久 kn-aut-sei=吉利 kn-aut-mei=宗久 aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Education Doctoral Programs, Hyogo University of Teacher Education kn-affil=兵庫教育大学大学院連合学校教育学研究科博士課程 affil-num=2 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=小児がん (child hood cancer) kn-keyword=小児がん (child hood cancer) en-keyword=慢性疾患 (chronic illness) kn-keyword=慢性疾患 (chronic illness) en-keyword=教育的ニーズ (educational needs) kn-keyword=教育的ニーズ (educational needs) en-keyword=研究動向 (research trends) kn-keyword=研究動向 (research trends) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=325 end-page=339 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Recommendations on how to View STEAM Education in General Education and Development of Classes and Teacher Training –Through the Enrichment of Integrated Inquiry Time– kn-title=普通科における STEAM 教育の捉え方の提言と授業および教員研修の開発　―総合的な探究の時間の充実を通して― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本実践報告では，普通科における STEAM 教育の捉え方を提言し，具体的な授業実践や教員研修を提案する。先行研究等で議論されている STEAM 教育の概念等から，STEAM 教育の根幹は創造性を涵養・刺激・発揮する教育であると捉え，STEAM 教育と最も親和性が高い総合的な探究の時間で授業実践を行った。取り組みの効果については，成果物の分析やヒアリング調査等を通して検証し，探究を自分事にできていることが示唆された。また，生徒が創造性を涵養・刺激・発揮する場面は，各教科等の授業内でも実現できると考え，「楽しく深まる授業」をテーマにした教員研修の開発を行った。この研修では授業開発を教員のチーム探究と捉え，総合的な探究の時間で生徒が取り組むワーク等も活用した。総合的な探究の時間を受けた経験のない教員が探究活動のプロセスを経験し，探究の楽しさやワクワク感を実感できることも狙っている。主体的で活発な全校研修が実現し，教員が探究的に授業創りを進めることのできる研修の仕掛けを見出すことができた。 en-copyright= kn-copyright= en-aut-name=EBARAMitsuo en-aut-sei=EBARA en-aut-mei=Mitsuo kn-aut-name=江原光夫 kn-aut-sei=江原 kn-aut-mei=光夫 aut-affil-num=1 ORCID= en-aut-name=INADAYoshihiko en-aut-sei=INADA en-aut-mei=Yoshihiko kn-aut-name=稲田佳彦 kn-aut-sei=稲田 kn-aut-mei=佳彦 aut-affil-num=2 ORCID= affil-num=1 en-affil=Okayama Prefectural Kurashiki Amaki High School (Graduate School of Education (Professional Degree Corse), Okayama University) kn-affil=岡山大学大学院教育学研究科大学院生 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=STEAM 教育 (STEAM education) kn-keyword=STEAM 教育 (STEAM education) en-keyword=創造性 (creativity) kn-keyword=創造性 (creativity) en-keyword=総合的な探究の時間 (integrated inquiry time) kn-keyword=総合的な探究の時間 (integrated inquiry time) en-keyword=普通科 (general education) kn-keyword=普通科 (general education) en-keyword=教員研修 (teacher training) kn-keyword=教員研修 (teacher training) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=313 end-page=324 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An Attempt at International Understanding Education Incorporating Letter Exchange Activities between Japanese and Chinese High School Students: Through Development of a Civics Unit Plan on International Issues kn-title=日中の高校生の手紙を使った交流活動を取り入れた国際理解教育の試み　―国際的課題を取り上げた公民科の単元開発― en-subtitle= kn-subtitle= en-abstract=This study reports the results of the development and practice of a class in which Japanese and Chinese high school students deepened mutual understanding and became aware of themselves as members of the international community through l earning activities in which they exchanged letters in order to share their thoughts on a global international issue. Through the practice, it became clear that exchange activities have the following significance for students. Firstly, it was the first one-on-one exchange with a foreigner. Even if they did not meet directly, for many of the students in this class, it was their first experience to interact with people from other countries. Secondly, it was an opportunity for them to develop an interest in other cultures and schools. Thirdly, the students were able to consider the issue of climate change from a global perspective. kn-abstract=　本研究は，日本と中国の高校生が地球規模の国際的課題について考えを共有するために，手紙を交換する学習活動を通して相互理解を深め，国際社会の一員としての自覚を持つようになることを目指した授業の開発・実践の成果を報告するものである。実践を通して，交流活動は生徒にとって次のような意義があることが明らかになった。第ーは，外国人との初めての一対一の交流であったということである。直接会わない形であったとしても，今回の授業を受けた多くの生徒にとっては他の国の人と関わる初めての経験であった。第二は，他国の文化や学校への関心を持つきっかけとなったことである。第三は，気候変動問題に対してグローバルな視点で考えるきっかけを与えられたということである。 en-copyright= kn-copyright= en-aut-name=BEKKIMoeka en-aut-sei=BEKKI en-aut-mei=Moeka kn-aut-name=別木萌果 kn-aut-sei=別木 kn-aut-mei=萌果 aut-affil-num=1 ORCID= en-aut-name=ZHOUXingxing en-aut-sei=ZHOU en-aut-mei=Xingxing kn-aut-name=周星星 kn-aut-sei=周 kn-aut-mei=星星 aut-affil-num=2 ORCID= en-aut-name=KUWABARAToshinori en-aut-sei=KUWABARA en-aut-mei=Toshinori kn-aut-name=桑原敏典 kn-aut-sei=桑原 kn-aut-mei=敏典 aut-affil-num=3 ORCID= affil-num=1 en-affil=Tokyo Metropolitan Ogawa High School kn-affil=東京都立小川高等学校 affil-num=2 en-affil=School of Foreign Languages, Shijiazhuang University kn-affil=石家荘学院外国語学院（中国） affil-num=3 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=国際理解教育 (international understanding education) kn-keyword=国際理解教育 (international understanding education) en-keyword=公民科 (civics) kn-keyword=公民科 (civics) en-keyword=単元開発 (unit development) kn-keyword=単元開発 (unit development) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=297 end-page=311 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Exploring Home Learning That Bridges Lessons to Foster Autonomous and Self-Directed Learning kn-title=主体的・自律的な学びを萌芽させる「授業と授業をつなぐ家庭学習」の探究 en-subtitle= kn-subtitle= en-abstract=　For students to develop the ability to learn independently, they need learning experiences that extend beyond the classroom, including at home. In other words, learning is not confined to the classroom but is reinforced through a wide range of activities. This study aimed to nurture “autonomous and self-directed learning” among students in the second grade at a public junior high school by integrating classroom and home learning. Teachers emphasized the importance of learning strategies and goal setting, and encouraged metacognition. As a result, students became more aware of the self-regulated learning cycle and began exploring learning strategies tailored to their needs. In addition, working at home on assignments connected to the class not only increased students’ active participation in class but also improved their motivation to learn independ ently outside of class. kn-abstract=　生徒が自ら学習を進めていく力を身に付けるには，授業内だけでなく，家庭など授業外の場での学習経験を積む必要がある。つまり，学習は授業内だけで完結するのではなく，広範な活動を通して成立する。本研究では，公立中学校の第2学年を対象に授業と家庭学習を連携させる実践を行い，生徒の「主体的・自律的な学び」を萌芽させることを目指した。教師が学習方略や目標設定の重要性を伝え，メタ認知を促すことで，生徒は自己調整学習のサイクルを意識し，自分なりの学習方略を探求するようになった。また，家庭学習で授業につながる課題に取り組むことで，授業への主体的な参加と，授業外で自律的に学ぶ意欲が促されることも示唆された。 en-copyright= kn-copyright= en-aut-name=TANAKAJunko en-aut-sei=TANAKA en-aut-mei=Junko kn-aut-name=田中純子 kn-aut-sei=田中 kn-aut-mei=純子 aut-affil-num=1 ORCID= en-aut-name=MISAWARyo en-aut-sei=MISAWA en-aut-mei=Ryo kn-aut-name=三沢良 kn-aut-sei=三沢 kn-aut-mei=良 aut-affil-num=2 ORCID= affil-num=1 en-affil=Okayama Municipal Hosen Junior High School kn-affil=岡山市立芳泉中学校 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=授業と家庭学習の連携 (coordination between classroom and home learning) kn-keyword=授業と家庭学習の連携 (coordination between classroom and home learning) en-keyword=自己調整学習 (self-regulated learning) kn-keyword=自己調整学習 (self-regulated learning) en-keyword=宿題 (homework) kn-keyword=宿題 (homework) en-keyword=授業改善 (lesson improvement) kn-keyword=授業改善 (lesson improvement) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=281 end-page=295 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Development Support a Child with Autism to Acquisition of Intersubjective Communication: Through the Environmental Setting of Play with Shared Positive Emotions kn-title=ASD 児における相互伝達行為の獲得を目指した遊びを中心としたコミュニケーション指導　ポジティブな情動の共有を生み出す遊びの環境設定を通して en-subtitle= kn-subtitle= en-abstract=In this study, a play-based instruction was used to promote the acquisition of intersubjective communication in a special needs school for students with intellectual disabilities. The participant was a first-grade boy with autism. As a result, the boy began to show intersubjective communication and to respond to the teacher's instruction. It was suggested that four aspects of the play environment may have promoted the acquisition of intersubjective communication: 1) attractive toys, 2) play with the teacher through attractive toys, 3) intervention according to the developmental process of the target children's play, and 4) empathic involvement to encourage the affective sharing. kn-abstract=　自閉スペクトラム症児は，相互伝達行為の獲得に遅れがあることが指摘されている。本研究では，自閉スペクトラム症の診断のある知的障害特別支援学校小学部１年生男児を対象に，相互伝達行為の獲得を目指して，遊びを中心とした指導を行った。その結果，対象児の遊びが「感覚運動的遊び」「機能的遊び」から「象徴的遊び」「社会的遊び」へと移行するに伴い，相互伝達行為が見られるようになった。また，教師による働き掛けへの応答も見られるようになり，ポジティブな情動の共有が生み出されやすい遊びの環境設定が，相互伝達行為の獲得において効果的であったことが示唆された。遊び環境については，1）魅力的な玩具，2）魅力的な玩具を介した教師との遊び，3）対象児の遊びの発達段階に応じた介入，4）情動の共有を促す共感的関わりの４点が相互伝達行為の獲得を促した可能性が考えられた。 en-copyright= kn-copyright= en-aut-name=KAKUHARAKeisuke en-aut-sei=KAKUHARA en-aut-mei=Keisuke kn-aut-name=角原佳介 kn-aut-sei=角原 kn-aut-mei=佳介 aut-affil-num=1 ORCID= en-aut-name=BANMarina en-aut-sei=BAN en-aut-mei=Marina kn-aut-name=伴真里奈 kn-aut-sei=伴 kn-aut-mei=真里奈 aut-affil-num=2 ORCID= en-aut-name=TANJITakayuki en-aut-sei=TANJI en-aut-mei=Takayuki kn-aut-name=丹治敬之 kn-aut-sei=丹治 kn-aut-mei=敬之 aut-affil-num=3 ORCID= affil-num=1 en-affil=Tobi Special School kn-affil=岡山県立東備支援学校 affil-num=2 en-affil=Special School Affiliated with the Faculty of Education at Okayama University kn-affil=岡山大学教育学部附属特別支援学校 affil-num=3 en-affil=Institute of Human Sciences, University of Tsukuba kn-affil=筑波大学人間系 en-keyword=自閉スペクトラム症 (a Child with Autism) kn-keyword=自閉スペクトラム症 (a Child with Autism) en-keyword=相互伝達行為 (Intersubjective Communication) kn-keyword=相互伝達行為 (Intersubjective Communication) en-keyword=情動の共有 (effective sharing) kn-keyword=情動の共有 (effective sharing) en-keyword=遊びの環境設定 (Setting of Play) kn-keyword=遊びの環境設定 (Setting of Play) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=267 end-page=279 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Examination of Practical Cases of Career Education to Promote Self-Understanding in Elementary School Students: Utilizing Character Strengths Intervention kn-title=児童の自己理解を促すキャリア教育の実践事例の検討　―強み介入を活用して― en-subtitle= kn-subtitle= en-abstract=This study explored the implementation of Character Strengths Intervention (CSI), rooted in positive psychology, to enhance self-awareness in career education for elementary school students. The intervention targeted 4th-grade students at a public elementary school, aiming to facilitate their recognition and utilization of character strengths in relation to future aspirations. Through structured lessons, students deepened their understanding of personal strengths and developed increased awareness of how to apply these attributes towards their future goals. Moreover, peer-focused activities designed to acknowledge individual strengths contributed to improved interpersonal relationships among students. However, challenges persist, including the need for comprehensive systematic and developmental planning of career education across the entire school, as well as providing tailored support for students who find it difficult to identify and leverage their unique strengths. kn-abstract=本研究では，公立小学校4年生を対象に，キャリア教育における自己理解能力の育成を目的とし，ポジティブ心理学に基づく性格特性的強み介入 (Character Strengths Intervention：CSI) と将来の夢についての学習を関連付けた学級活動 (３) の授業を行った。本実践を通して，児童は自分の強みを理解し，それを将来に活かそうとする意識が高まるとともに，互いの強みを認め合う活動によって児童同士の関係性の構築が促進された。一方で，学校全体でのキャリア教育の系統性と発展性の検討，強みの活用が難しい児童への個別支援の必要性が今後の課題として指摘された。 en-copyright= kn-copyright= en-aut-name=YOSHIKAWAShinji en-aut-sei=YOSHIKAWA en-aut-mei=Shinji kn-aut-name=吉川伸二 kn-aut-sei=吉川 kn-aut-mei=伸二 aut-affil-num=1 ORCID= en-aut-name=ISODAKouhei en-aut-sei=ISODA en-aut-mei=Kouhei kn-aut-name=磯田浩平 kn-aut-sei=磯田 kn-aut-mei=浩平 aut-affil-num=2 ORCID= en-aut-name=IZUMITsuguyuki en-aut-sei=IZUMI en-aut-mei=Tsuguyuki kn-aut-name=伊住継行 kn-aut-sei=伊住 kn-aut-mei=継行 aut-affil-num=3 ORCID= affil-num=1 en-affil=Uwanari Elementary School kn-affil=倉敷市立上成小学校 affil-num=2 en-affil=Uwanari Elementary School kn-affil=倉敷市立上成小学校 affil-num=3 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=キャリア教育 (Career Education) kn-keyword=キャリア教育 (Career Education) en-keyword=自己理解 (Self-awareness) kn-keyword=自己理解 (Self-awareness) en-keyword=性格特性的強み (Character Strengths) kn-keyword=性格特性的強み (Character Strengths) en-keyword=学級活動 (３) (Classroom Activities (3)) kn-keyword=学級活動 (３) (Classroom Activities (3)) en-keyword=児童 (Children) kn-keyword=児童 (Children) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=251 end-page=265 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Bridging the Gap: Outcomes and Challenges of a Collaborative Start Curriculum for Seamless Transition to Elementary School kn-title=小学校への滑らかな移行を支えるスタートカリキュラム共同編成プロジェクトの成果と課題 en-subtitle= kn-subtitle= en-abstract=In this practice, a joint curriculum development project was launched to ease the transition for children in the “bridge period” from age five to first grade, involving five discussions between kindergarten and elementary school teachers. Participants reflected on these discussions, and the content was analyzed. (1) A screening sheet to identify children who “cause concern” helped clarify differences in observations, leading to a shared understanding of child perceptions. (2) Teachers recognized differences in their views of children and education, improving their attitudes toward compromise and increasing awareness of the need to smooth the transition. However, an overloaded elementary school curriculum was noted, limiting the flexible application of the start curriculum and hindering child-centered education. kn-abstract=本実践では，５歳児から小学１年生の「架け橋期」の滑らかな移行に焦点を当てたスタートカリキュラム共同編成プロジェクトを立ち上げ，幼稚園と小学校の教員が集まって５回の話合いを行った。本プロジェクトを評価するために，参加者に話合いの振返りを書いてもらい，その内容を検討した。成果として，①スクリーニングシートを使って，「気になる」子供を抽出し，見取りの違いを可視化することで，相互の子供観について共通理解を図ることができた。②幼稚園と小学校，双方の教員が互いの子供観・教育観の違いを理解し，歩み寄ろうとする姿勢や校種間の接続をより滑らかにしようとする意識の向上が確認された。一方，課題として，スタートカリキュラムの柔軟な運用や小学校教育における子供主体の教育の実現を妨げる教育課程の過積載状態の問題が指摘された。 en-copyright= kn-copyright= en-aut-name=OKURAHisashi en-aut-sei=OKURA en-aut-mei=Hisashi kn-aut-name=大倉尚志 kn-aut-sei=大倉 kn-aut-mei=尚志 aut-affil-num=1 ORCID= en-aut-name=MATSUINoriko en-aut-sei=MATSUI en-aut-mei=Noriko kn-aut-name=松井紀子 kn-aut-sei=松井 kn-aut-mei=紀子 aut-affil-num=2 ORCID= en-aut-name=IZUMITsuguyuki en-aut-sei=IZUMI en-aut-mei=Tsuguyuki kn-aut-name=伊住継行 kn-aut-sei=伊住 kn-aut-mei=継行 aut-affil-num=3 ORCID= affil-num=1 en-affil=Hayashima Kindergarten kn-affil=早島町立早島幼稚園 affil-num=2 en-affil=Hayashima Kindergarten kn-affil=早島町立早島幼稚園 affil-num=3 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=架け橋プログラム (Bridge Program) kn-keyword=架け橋プログラム (Bridge Program) en-keyword=スタートカリキュラム (Start Curriculum) kn-keyword=スタートカリキュラム (Start Curriculum) en-keyword=スクリーニングシート (Screening Sheet) kn-keyword=スクリーニングシート (Screening Sheet) en-keyword=カリキュラム・オーバーロード (Curriculum Overload) kn-keyword=カリキュラム・オーバーロード (Curriculum Overload) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=235 end-page=249 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Practical Research on Nurturing the Next Generation of Classical Japanese Instrument Music That Connects the Local and the Global Community (1): Analysis of External Evaluations of the “Okayama International Classical Japanese Instruments Student Festival” kn-title=地域社会とグローバルをつなぐ和楽器音楽次世代育成の実践研究（１）　「おかやま国際和楽器学生フェスティバル」外的評価の分析 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿では，「和楽器音楽及び教育の拠点づくりの実践研究」の一環として開催した「おかやま国際和楽器学生フェスティバル」の取り組みについて，その概要を報告するとともに，外的評価として「おかやま国際和楽器学生フェスティバルコンサート」終演後に実施した一般来場者対象の質問紙調査及びフェスティバルを参観した岡山県内の学校関係者対象の質問紙調査を取り上げ，意義と課題について検討した。
　その結果，第一に音楽を通じた世代間や国際交流の喜びを感じ，和楽器の伝承と教育の重要性を強く意識する機会となったこと，第二に，和楽器が様々な国籍・年齢の学生に受容されていることを，来場者が客観視することで，自文化の価値の再認識につながったこと，第三に，フェスティバル全体としては，ワークショップが充実しており，様々な国籍・年齢の学生が同じステージで演奏する姿に対する評価が得られた点が明らかとなった。 en-copyright= kn-copyright= en-aut-name=HAYAKAWARinko en-aut-sei=HAYAKAWA en-aut-mei=Rinko kn-aut-name=早川倫子 kn-aut-sei=早川 kn-aut-mei=倫子 aut-affil-num=1 ORCID= en-aut-name=YAMAJIMiho en-aut-sei=YAMAJI en-aut-mei=Miho kn-aut-name=山路みほ kn-aut-sei=山路 kn-aut-mei=みほ aut-affil-num=2 ORCID= en-aut-name=TAKASUHiromi en-aut-sei=TAKASU en-aut-mei=Hiromi kn-aut-name=髙須裕美 kn-aut-sei=髙須 kn-aut-mei=裕美 aut-affil-num=3 ORCID= en-aut-name=BEPPUYuko en-aut-sei=BEPPU en-aut-mei=Yuko kn-aut-name=別府祐子 kn-aut-sei=別府 kn-aut-mei=祐子 aut-affil-num=4 ORCID= en-aut-name=HIGUCHIAki en-aut-sei=HIGUCHI en-aut-mei=Aki kn-aut-name=樋口亜希 kn-aut-sei=樋口 kn-aut-mei=亜希 aut-affil-num=5 ORCID= en-aut-name=NAKAMURAAi en-aut-sei=NAKAMURA en-aut-mei=Ai kn-aut-name=中村愛 kn-aut-sei=中村 kn-aut-mei=愛 aut-affil-num=6 ORCID= en-aut-name=SHIMIZUNaoko en-aut-sei=SHIMIZU en-aut-mei=Naoko kn-aut-name=清水尚子 kn-aut-sei=清水 kn-aut-mei=尚子 aut-affil-num=7 ORCID= en-aut-name=HANAKUSAYoko en-aut-sei=HANAKUSA en-aut-mei=Yoko kn-aut-name=花草容子 kn-aut-sei=花草 kn-aut-mei=容子 aut-affil-num=8 ORCID= en-aut-name=TAKESHITANoriko en-aut-sei=TAKESHITA en-aut-mei=Noriko kn-aut-name=竹下則子 kn-aut-sei=竹下 kn-aut-mei=則子 aut-affil-num=9 ORCID= en-aut-name=MIYOSHIKeiko en-aut-sei=MIYOSHI en-aut-mei=Keiko kn-aut-name=三好啓子 kn-aut-sei=三好 kn-aut-mei=啓子 aut-affil-num=10 ORCID= en-aut-name=TOSAChihiro en-aut-sei=TOSA en-aut-mei=Chihiro kn-aut-name=土佐千紘 kn-aut-sei=土佐 kn-aut-mei=千紘 aut-affil-num=11 ORCID= affil-num=1 en-affil=Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Koto Player kn-affil=箏曲演奏家・岡山大学非常勤講師 affil-num=3 en-affil=Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=4 en-affil=Kurashiki City College kn-affil=倉敷市立短期大学 affil-num=5 en-affil=Okayama Prefectural School for the Deaf kn-affil=岡山県立岡山聾学校 affil-num=6 en-affil=Doctoral Student at the Joint Graduate School in Science of School Education Hyogo University of Teacher Education kn-affil=兵庫教育大学大学院連合学校教育学研究科博士課程 affil-num=7 en-affil=Doctoral Student at the Joint Graduate School in Science of School Education Hyogo University of Teacher Education kn-affil=兵庫教育大学大学院連合学校教育学研究科博士課程 affil-num=8 en-affil=Research Student at the Joint Graduate School in Science of School Education Hyogo University of Teacher Education kn-affil=兵庫教育大学大学院連合学校教育学研究科研究生 affil-num=9 en-affil=Research Student at the Joint Graduate School in Science of School Education Hyogo University of Teacher Education kn-affil=兵庫教育大学大学院連合学校教育学研究科研究生 affil-num=10 en-affil=Master’s Student at the Graduate School of Education in Okayama University kn-affil=岡山大学大学院教育学研究科修士課程 affil-num=11 en-affil=Master’s Student at the Graduate School of Education in Okayama University kn-affil=岡山大学大学院教育学研究科修士課程 en-keyword=和楽器音楽 (Classical Japanese instrument) kn-keyword=和楽器音楽 (Classical Japanese instrument) en-keyword=教育 (education) kn-keyword=教育 (education) en-keyword=次世代育成 (nurturing the next generation) kn-keyword=次世代育成 (nurturing the next generation) en-keyword=グローカル (glocal) kn-keyword=グローカル (glocal) en-keyword=質問紙調査 (questionnaire survey) kn-keyword=質問紙調査 (questionnaire survey) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=219 end-page=233 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Practice of Aging Studies in Middle School Home Economics –Considering Aging in the Life Course– kn-title=中学校家庭科における高齢期学習の実践　―ライフコースの中で高齢期を考える― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究では，中学校家庭科における高齢期学習の授業実践を通して，中学生が高齢期を自らのライフコースの中で考えることができるかを明らかにすることを目的とし，中学生を対象に高齢者，高齢期学習を実践した。中学校家庭科における高齢者や高齢期に関連する学習内容を確認するため，『中学校学習指導要領（平成29年告示）解説技術・家庭編』と家庭科の教科書を分析した。中学生が高齢者，高齢期に関して自分のライフコースの一部として考えることができるように学習指導案を作成し，岡山県内のT中学校3年生を対象に授業を行った。授業実践の結果，学習の深まりを感じたと回答した中学生が多く，高齢期を将来の自らのライフコースの中で考えられるようになった中学生も少なくないことを確認できた。しかし，高齢者に関する学習をより望む中学生が半数を下回り，中学生が更なる学習の意欲や興味を持てるような学習方法の工夫が必要であることも明らかになった。 en-copyright= kn-copyright= en-aut-name=TAKATAMihoko en-aut-sei=TAKATA en-aut-mei=Mihoko kn-aut-name=高田水穂子 kn-aut-sei=高田 kn-aut-mei=水穂子 aut-affil-num=1 ORCID= en-aut-name=LEEKyoungwon en-aut-sei=LEE en-aut-mei=Kyoungwon kn-aut-name=李璟媛 kn-aut-sei=李 kn-aut-mei=璟媛 aut-affil-num=2 ORCID= affil-num=1 en-affil=Student At Graduate School of Education, Okayama University kn-affil=岡山大学大学院教育学研究科大学院生 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=高齢者 kn-keyword=高齢者 en-keyword=高齢期 kn-keyword=高齢期 en-keyword=中学校家庭科 kn-keyword=中学校家庭科 en-keyword=学習指導要領 kn-keyword=学習指導要領 en-keyword=教科書 kn-keyword=教科書 en-keyword=Elderly (Aging) kn-keyword=Elderly (Aging) en-keyword=junior High School Technology-Home Economics (Home Economics) kn-keyword=junior High School Technology-Home Economics (Home Economics) en-keyword=Courses of Study Textbooks kn-keyword=Courses of Study Textbooks END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=207 end-page=218 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Lesson Structure of Elementary Social Studies Law-Related Education Focusing on the Concept of Contract: Through the Designing of a Unit on Production and Sales in the Third Grade kn-title=契約概念に注目した小学校社会科法教育の授業構成　―第３学年の生産や販売に関する単元の開発を通して― en-subtitle= kn-subtitle= en-abstract=This paper clarifies the Lesson Theory of Law-Related Education as citizenship education in elementary social studies, clarifies the Theory of lesson structure, and develops a unit on sales work in the middle grades. Research has been conducted in elementary Law-Related Education based on the theory of developmental psychology, but systematization as elementary social studies has not been promoted. In the elementary school social studies, the content of the third grade "about the work of production and sales found in the community" is set. Sales equally involve legal issues such as sales contracts. this paper suggests an elementary social studies unit using a supermarket as a teaching material, based on Law-Related Education research accumulated in social studies education research to date. kn-abstract=　本論文は、小学校社会科における市民性教育としての法教育のあり方を検討し、その授業構成原理を明らかにしたうえで、中学年の教育内容である販売の仕事に関する単元開発を行うものである。これまで小学校法教育では、発達心理学の論を基にしながら研究が進められてきたが、小学校社会科法教育としての体系的な研究は十分ではなかった。小学校第３学年の社会科では、第３学年「地域にみられる生産や販売の仕事について」の内容が設定されている。佐藤はスーパーマーケットを教材として小学校社会科で経済概念を形成する授業を開発し、その有効性を検証した。一方で、販売には売買契約のような法的問題も発生する。本論文では、これまでの社会科教育研究において蓄積されてきた法教育論や価値観形成論の成果を踏まえ、スーパーマーケットを教材とした小学校社会科単元開発を行う。 en-copyright= kn-copyright= en-aut-name=MIYAMOTOAyuha en-aut-sei=MIYAMOTO en-aut-mei=Ayuha kn-aut-name=宮本あゆは kn-aut-sei=宮本 kn-aut-mei=あゆは aut-affil-num=1 ORCID= en-aut-name=KUWABARAToshinori en-aut-sei=KUWABARA en-aut-mei=Toshinori kn-aut-name=桑原敏典 kn-aut-sei=桑原 kn-aut-mei=敏典 aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Humanities and Social Sciences, Okayama University kn-affil=岡山大学大学院社会文化科学研究科博士後期課程 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=法教育 (Law-Related Education) kn-keyword=法教育 (Law-Related Education) en-keyword=初等教育 (Elementary School Education) kn-keyword=初等教育 (Elementary School Education) en-keyword=小学校社会科 (Social Studies) kn-keyword=小学校社会科 (Social Studies) en-keyword=民法学習 (Civil Law Education) kn-keyword=民法学習 (Civil Law Education) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=191 end-page=205 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Prevention of Apathy in High School Students Perspective on Time Management and Future Prospects kn-title=アパシー傾向からみた高校生の無気力の予防について　―タイムマネジメント，将来展望との関係を通して― en-subtitle= kn-subtitle= en-abstract=　According to the Ministry of Education in Japan (2023), apathy is the leading cause of truancy among high school students, with the percentage of nonattendance at 40%. Therefore, this study aimed to examine the prevention of apathy among high school students. Apathy among college students has been examined as a propensity for apathy. This study presupposes that apathy among high school students is also associated with a propensity for apathy. Two hundred and nineteen high school students were participated in this research. We assumed time management (TM) and future prospects (self-fulfillment, goal-directedness, and hopefulness) would be preventive factors against apathetic tendencies for them. The study findings indicate that self-fulfillment may significantly reduce apathy, with hopefulness also contributing to reducing apathy. Additionally, the characteristics of apathy tendency, specifically lack of self, were found to be differently related to students' TM skills. In other words, the findings suggest that goal-directedness may alleviate apathy among students struggling with TM. kn-abstract=　不登校の主たる要因の1位は「無気力・不安」で40.0%を占める（文部科学省，2023）。このことは，不登校でない生徒の中にも，無気力を感じている生徒がかなりいることを示唆している。そこで本研究は，高校生の無気力とその予防について検討する。無気力は，大学生を対象にアパシー傾向として検討されてきた。そこで高校生の無気力をアパシー傾向として捉え，加えてそれを予防するものについても併せて検討した。予防法の候補として，タイムマネジメント（以下，TM）と将来展望（現在の充実感・目標指向性・希望）を想定し，高校生219名を対象に，これらの関係を検討した。分析の結果，無気力を低減するのは，現在の充実感，希望であり，特に前者が有効である可能性を示せた。一方で，アパシー傾向の自分のなさでは，TM のタイプによって異なる関係がみられた。つまり，TM が苦手な生徒では，希望よりも，目前の目標に目を向けることが無気力を低減できる可能性が示唆された。 en-copyright= kn-copyright= en-aut-name=ASADAAsuka en-aut-sei=ASADA en-aut-mei=Asuka kn-aut-name=麻田明日香 kn-aut-sei=麻田 kn-aut-mei=明日香 aut-affil-num=1 ORCID= en-aut-name=AOKITazuko en-aut-sei=AOKI en-aut-mei=Tazuko kn-aut-name=青木多寿子 kn-aut-sei=青木 kn-aut-mei=多寿子 aut-affil-num=2 ORCID= affil-num=1 en-affil=KANKO GAKUSEIFUKU CO., LTD. kn-affil=菅公学生服 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域　教授 en-keyword=高校生 (High School Students) kn-keyword=高校生 (High School Students) en-keyword=無気力 kn-keyword=無気力 en-keyword=アパシー傾向 (Apathy tendency) kn-keyword=アパシー傾向 (Apathy tendency) en-keyword=タイムマネジメント (Time Management) kn-keyword=タイムマネジメント (Time Management) en-keyword=将来展望 (Future Prospect) kn-keyword=将来展望 (Future Prospect) en-keyword=Prevention kn-keyword=Prevention END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=179 end-page=190 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Current Trends and Future Issues Related to Song’s speed in the Preschool-Elementary Cooperated Education Research kn-title=幼児歌唱曲の速度感の傾向と課題 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究では，音楽教育的観点から幼児歌唱曲の選定のあり方を検討した。その際，小学校の音楽教育で歌唱共通課題として挙げられてきた教材を比較対象とし，その傾向と課題を考察する。１つ目は曲の速度感において歌唱共通教材と選定頻度の高い幼児歌唱曲の平均的な速度において，どの程度の差があるのかという調査を行った。２つ目は，幼稚園と小学校音楽科で共通して用いられる教材曲の作曲された年代の違いについて明らかにした。この２つの調査を用いて，歌唱共通課題に選定されている曲の速度感から現代の子どもの歌の速度感の傾向を明らかにした。この結果から幼稚園教育における幼児歌唱曲のチャートを作成することによって，伝統的に歌い継がれてきた幼児歌唱曲の再考の可能性を示した。 en-copyright= kn-copyright= en-aut-name=TAKASUHiromi en-aut-sei=TAKASU en-aut-mei=Hiromi kn-aut-name=髙須裕美 kn-aut-sei=髙須 kn-aut-mei=裕美 aut-affil-num=1 ORCID= affil-num=1 en-affil=Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=幼保小連携 (Preschool-elementary cooperation) kn-keyword=幼保小連携 (Preschool-elementary cooperation) en-keyword=子供の歌の速度感 (Children’s Song speed) kn-keyword=子供の歌の速度感 (Children’s Song speed) en-keyword=子供の歌文化 (Children’s singing culture) kn-keyword=子供の歌文化 (Children’s singing culture) en-keyword=伝統音楽 (Japanese traditional song materials) kn-keyword=伝統音楽 (Japanese traditional song materials) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=163 end-page=177 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Climate and Songs of Spring/May Around Germany (Part Ⅱ): A Report of an Interdisciplinary Lesson Practice at the University Leading to the Understanding of Heterogeneous Others kn-title=ドイツ付近の春・５月の気候と歌（その２）：異質な他者への出会いを促す大学での学際的授業の実践 en-subtitle= kn-subtitle= en-abstract=An interdisciplinary lesson practice for the university students leading to the understanding of heterogeneous others was made on a topic of climate and songs of "spring/May" around Germany, as a continuing study of Kato et al. (2023b). In the lesson practice, details of the climate and seasonal cycle around Germany, in association with the seasonal feeling of the special season May, were firstly presented. Then, several German lieder, a film music, etc. were appreciated, paying attention to the relation between expressions of the songs and their climate backgrounds. It seems that the students were able to realize the characteristic expressions of the songs relating to the seasonal feeling of "the special season May" around Germany, mainly from the song lyrics, although how to promote further the students' deepening of such perception including musical expressions themselves is a remaining problem. kn-abstract=　ドイツ付近の「春・5月」の気候と歌の表現の学際的学習を通して「異質な他者」への出会いを促す教科横断的授業を大学で行った。授業では，ドイツ付近における「春・5月」の季節感の2つの側面，すなわち「厳しい冬を経て巡り来る特別な喜び」や「すぐに過ぎ去る至福の瞬間の儚さ」に関連した気候の特徴を講義すると共に，それらの季節感が表現されたドイツ歌曲や映画《会議は踊る》の主題歌〈ただ一度だけ〉等の鑑賞を行い，作品の背景にある気候と音楽表現の関りにアプローチした。その結果，作品の歌詞を主な手がかりに，気候や季節感と音楽表現の関りを概ね捉えることができた。従って，本実践が「異質な他者」の存在を実感する機会になり得たといえる。一方，「5月」という一語に凝縮されたドイツ付近ならではの深い内容を「我が事」としてより強く実感するためには，歌詞はもとより音楽的表現との絡みを意識した捉え方，提示の必要性が示唆された。 en-copyright= kn-copyright= en-aut-name=KATOKuranoshin en-aut-sei=KATO en-aut-mei=Kuranoshin kn-aut-name=加藤内藏進 kn-aut-sei=加藤 kn-aut-mei=内藏進 aut-affil-num=1 ORCID= en-aut-name=NAGAOKAIsao en-aut-sei=NAGAOKA en-aut-mei=Isao kn-aut-name=長岡功 kn-aut-sei=長岡 kn-aut-mei=功 aut-affil-num=2 ORCID= en-aut-name=KATOHaruko en-aut-sei=KATO en-aut-mei=Haruko kn-aut-name=加藤晴子 kn-aut-sei=加藤 kn-aut-mei=晴子 aut-affil-num=3 ORCID= en-aut-name=OTANIKazuo en-aut-sei=OTANI en-aut-mei=Kazuo kn-aut-name=大谷和男 kn-aut-sei=大谷 kn-aut-mei=和男 aut-affil-num=4 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=3 en-affil=Faculty of Education, Gifu Shotoku Gakuen University (Former affiliation) kn-affil=元　岐阜聖徳学園大学教育学部 affil-num=4 en-affil=TV Setouchi Broadcasting Co., LTD. kn-affil=テレビせとうち（株） en-keyword=気候と音楽 (Climate and music) kn-keyword=気候と音楽 (Climate and music) en-keyword=ドイツ付近の春・5月の気候と季節感 (Climate and seasonal feeling in spring/May around Germany) kn-keyword=ドイツ付近の春・5月の気候と季節感 (Climate and seasonal feeling in spring/May around Germany) en-keyword=ESD 教師教育 (Teacher education on ESD) kn-keyword=ESD 教師教育 (Teacher education on ESD) en-keyword=異質な他者への理解 (Understanding of heterogeneous others) kn-keyword=異質な他者への理解 (Understanding of heterogeneous others) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=147 end-page=161 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Teacher Response Processes to Behavioral Problems in Students with Mild Intellectual Disabilities: An Examination Based on Practices at High School Division of Special Needs School A kn-title=軽度知的障害のある生徒の行動問題への教員対応過程　―A 知的障害特別支援学校高等部での実践検討を通して― en-subtitle= kn-subtitle= en-abstract=The purpose of this study is to clarify the framework for teachers when addressing behavioral problems of students in the high school division of a special needs school for students with intellectual disabilities. The methodology involved conducting interviews with four experienced teachers from School A, a special needs school for students with intellectual disabilities, which had successfully navigated difficult periods due to challenges in student guidance. Qualitative analysis was conducted using the Modified Grounded Theory Approach (M-GTA). As a result, two core categories emerged: "Building relationships with individuals that foster a sense of security" and "Aiming for shared and unified approaches." Sixteen concepts were generated. When faced with behavioral problems, teachers focused on "Building relationships with individuals that foster a sense of security" as the axis for responding to students, while behind the scenes the teachers worked collectively toward "Aiming for shared and unified approaches." Finally, based on the framework clarified in this study, a hierarchical, comprehensive support system, including individualized support, was proposed. kn-abstract=　本研究の目的は，知的障害特別支援学校高等部に在籍する生徒の行動問題に着目し，学校現場で教員が適切に対応する際の枠組みを明らかにすることである。その方法として，生徒指導上の課題を理由とする教育困難期を乗り越えたA 知的障害特別支援学校高等部に所属していた経験豊富な教員4名に面接調査を実施し，M-GTA の手法を援用した質的分析を行った。その結果，【安心感を生む個との関係づくり】と【対応方法の共有と統一化を目指す】関係性がコア・カテゴリーと位置づき，16の諸概念を生成した。行動問題に直面した教員は，生徒に対しては【安心感を生む個との関係づくり】を対応の軸とし，その背後では学校として【対応方法の共有と統一化を目指す】ための動きをしていた。最後に，本研究で明らかとなった対応の枠組みについて考察した観点から，個別の時間を含む階層性のある包括的な支援システムを一つの提案とした。 en-copyright= kn-copyright= en-aut-name=TOKIMITSUHideaki en-aut-sei=TOKIMITSU en-aut-mei=Hideaki kn-aut-name=時光秀明 kn-aut-sei=時光 kn-aut-mei=秀明 aut-affil-num=1 ORCID= en-aut-name=MIYAZAKIYoshio en-aut-sei=MIYAZAKI en-aut-mei=Yoshio kn-aut-name=宮﨑善郎 kn-aut-sei=宮﨑 kn-aut-mei=善郎 aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Education (Professional Degree Course), Okayama University kn-affil=岡山大学大学院教育学研究科大学院生 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=高等部 (High school division) kn-keyword=高等部 (High school division) en-keyword=軽度知的障害 (Mild intellectual disabilities) kn-keyword=軽度知的障害 (Mild intellectual disabilities) en-keyword=発達障害 (Developmental disorders) kn-keyword=発達障害 (Developmental disorders) en-keyword=行動問題 (Behavioral problems) kn-keyword=行動問題 (Behavioral problems) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=133 end-page=145 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Image of Mushroom Created by Junior High School Science Textbooks: Suggestions for Learning about Mushroom from Diachronic Surveys kn-title=中学校理科教科書がつくり上げてきたきのこ像　―通時的調査から得るきのこを巡る学習への示唆― en-subtitle= kn-subtitle= en-abstract=　In this paper, we examined the image of mushroom in postwar junior high school science textbooks from four perspectives: (1) which species of mushroom were covered, (2) whether they were classified as plants or not, (3) what makes up the body of a mushroom, and (4) how they functioned in an ecosystem. The 47 species were identified through a periodic survey. Although a total of 47 species have appeared in science textbooks, we pointed out that in recent years, the focus has shifted to the role of mushroom as decomposers, rather than to species awareness. We also pointed out that although mycorrhizal fungi have been discussed in textbooks, there was no reference to the perspective in a plant-fungal symbiosis, which raises the possibility of developing learning that aims to understand symbiosis/interactions within a nature ecosystem. kn-abstract=　本稿では，戦後中学校理科検定教科書におけるきのこの扱われ方，すなわち学習者が受け取ることになるきのこ像について，①どのようなきのこが扱われてきたのか，②植物に分類されているか否か，③きのこのからだは何で形成されているのか，④生態系における働きの四つの観点から，通時的な調査によって明らかにした。全47種がこれまでの理科教科書で登場してきたが，近年は種への意識というよりも，きのこが分解者としての役割を持つことにのみ焦点が当てられてきていることを指摘した。また，これまで教科書においては菌根性のきのこ自体について取り上げられつつも，その生態系における相利共生の観点への言及はないことから，相利共生の理解を目指す学習の開発が可能性として浮かび上がってくることも指摘した。 en-copyright= kn-copyright= en-aut-name=TAKAGIRisa en-aut-sei=TAKAGI en-aut-mei=Risa kn-aut-name=髙木里彩 kn-aut-sei=髙木 kn-aut-mei=里彩 aut-affil-num=1 ORCID= en-aut-name=IKEDAMasafumi en-aut-sei=IKEDA en-aut-mei=Masafumi kn-aut-name=池田匡史 kn-aut-sei=池田 kn-aut-mei=匡史 aut-affil-num=2 ORCID= en-aut-name=YAMAMOTOMasaya en-aut-sei=YAMAMOTO en-aut-mei=Masaya kn-aut-name=山本将也 kn-aut-sei=山本 kn-aut-mei=将也 aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Education (Professional Degree Corse), Okayama University kn-affil=岡山大学大学院教育学研究科大学院生 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=3 en-affil=Hyogo University of Teacher Education kn-affil=兵庫教育大学大学院学校教育研究科 en-keyword=菌類 (Fungus) kn-keyword=菌類 (Fungus) en-keyword=菌根菌 (Mycorrhizal Fungi) kn-keyword=菌根菌 (Mycorrhizal Fungi) en-keyword=腐生菌 (Saprobic Fungi) kn-keyword=腐生菌 (Saprobic Fungi) en-keyword=相利共生 (Symbiosis) kn-keyword=相利共生 (Symbiosis) en-keyword=教材史 (History of teaching materials) kn-keyword=教材史 (History of teaching materials) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=119 end-page=132 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Development of Thoughts on the Effective Use of School Libraries and Collaboration with Teacher-Librarians and School Librarians in Japanese Language Arts: From a Survey of the Journal Kyoiku Kagaku Kokugo Kyoiku kn-title=学校図書館の活用と司書教諭・学校司書との協働をめぐる国語教育思潮の展開　―『教育科学国語教育』誌の調査から― en-subtitle= kn-subtitle= en-abstract=　School libraries are mentioned by government guidelines for teaching, and it is also closely related to Japanese language arts. Previous studies have reported the necessity of collaboration with teacher-librarians and school librarians. However, there has been no study of what kind of collaboration has been conducted in Japanese language arts to date. Therefore, the purpose of this study is to examine how school libraries are utilized in Japanese language arts based on a survey of educational journals, and to organize references to teacher-librarians and school librarians. As a result, we pointed out that while school libraries have been utilized in Japanese language arts in elementary and junior high schools, the collaboration with teacher-librarians and school librarians may not have been focused on, and that the reason for this is the lack of human resources, while some valuable collaborations can be found. kn-abstract=　学校図書館は，学習指導要領でも触れられており，国語科との関連も深い。また先行研究では，司書教諭や学校司書との協働の必要性が訴えられている。しかしこれまでの国語教育では，どのような協働がなされていたのかという検討がなされていない。そこで，本研究では，教育雑誌の調査をもとに，国語科においては，学校図書館がどのように活用されてきたのか，司書教諭や学校司書との協働はどのような態度がとられてきたのかを明らかにすることを目的とした。調査では，図書館に言及している論文や学校図書館を活用した実践・指導例を抽出し，分析した。実践・指導例の分析からは，小・中学校の国語科において学校図書館は活用されてきた一方で，司書教諭や学校司書との協働には着目が及んでいない状況が明らかになった。また，司書教諭や学校司書に関する言及からは，人的リソースにその原因を求める思潮が窺えたものの，価値ある協働も見受けられることを指摘した。 en-copyright= kn-copyright= en-aut-name=SAISHOYumi en-aut-sei=SAISHO en-aut-mei=Yumi kn-aut-name=最相有未 kn-aut-sei=最相 kn-aut-mei=有未 aut-affil-num=1 ORCID= en-aut-name=IKEDAMasafumi en-aut-sei=IKEDA en-aut-mei=Masafumi kn-aut-name=池田匡史 kn-aut-sei=池田 kn-aut-mei=匡史 aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Education（Professional Degree Corse），Okayama University kn-affil=岡山大学大学院教育学研究科大学院生 affil-num=2 en-affil=Faculty of Education，Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=雑誌調査 (survey of journals) kn-keyword=雑誌調査 (survey of journals) en-keyword=読書指導 (reading instruction) kn-keyword=読書指導 (reading instruction) en-keyword=探究的な学習 (inquiry-based learning) kn-keyword=探究的な学習 (inquiry-based learning) en-keyword=国語教育史 (history of Japanese Language Arts) kn-keyword=国語教育史 (history of Japanese Language Arts) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=107 end-page=118 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Analysis of Practical Results of the Liberal Arts Education Class “Creativity in Life” at Okayama University Ⅲ kn-title=大学教養教育における創造性を重視した探究型授業の評価　岡山大学教養教育科目「生活の中の創造性」の実践結果の分析Ⅲ en-subtitle= kn-subtitle= en-abstract=　Since 2022, in the liberal arts education course “Modernity and Society,” a class entitled “Creativity in Life” has been implemented, in which students propose “Okadai Goods” using “color” as the theme. According to the questionnaires conducted before and after the class, the students regarded creativity as “important for me,” were “interested in communicating with others and engaging in creative activities,” and changed their evaluation to a positive one, saying “I am creative” after the class. This class was found to be highly effective in promoting “awareness of one's own existence to think, feel, and judge independently and interactively. We believe that the main theme and the content of the inquiry activities in this class were suitable for the inquiry-based learning of university students. kn-abstract=　2022年より教養教育科目「現代と社会」において，「色」を主題にして「岡大グッズ」の提案を行う探究型授業「生活の中の創造性」を開講している。授業前後のアンケートによると，学生は「自分にとって創造性は重要」と捉え，「他者とコミュニケーションを取りながら創造的な活動をすることに興味」があり，授業後は「自分のことを創造的である」と肯定的な評価となっていた。この授業は「主体的，対話的に考え，感じ，判断する自分自身の存在を意識すること」を促す効果が大きいことが分かった。この３年間の実践は，主軸となるテーマと探究活動の内容が大学生の探究的な学びに適したものであったと考えている。 en-copyright= kn-copyright= en-aut-name=SHINOHARAYoko en-aut-sei=SHINOHARA en-aut-mei=Yoko kn-aut-name=篠原陽子 kn-aut-sei=篠原 kn-aut-mei=陽子 aut-affil-num=1 ORCID= en-aut-name=INADAYoshihiko en-aut-sei=INADA en-aut-mei=Yoshihiko kn-aut-name=稲田佳彦 kn-aut-sei=稲田 kn-aut-mei=佳彦 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=探究型授業 kn-keyword=探究型授業 en-keyword=創造性 (Creativity) kn-keyword=創造性 (Creativity) en-keyword=物理学 (Physics) kn-keyword=物理学 (Physics) en-keyword=被服学 (Clothing) kn-keyword=被服学 (Clothing) en-keyword=岡大グッズ (Okadai-Goods) kn-keyword=岡大グッズ (Okadai-Goods) en-keyword=ICT 活用 (ICT) kn-keyword=ICT 活用 (ICT) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=91 end-page=105 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Reflections of Early Care and Education Practitioners, as Indicated in the Content on the Care and Education of Kindergarten Children Published by Japan’s Ministry of Education, Culture, Sports, Science and Technology kn-title=幼稚園の保育全体に関する文部科学省公表資料に示されている保育者の振り返りの仕方の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究では，まず，我が国の保育施設におけるカリキュラム・マネジメントに関する先行研究を概観し，カリキュラム・マネジメントを実現するために必要な，保育の目標・ねらい・内容の連関性の確保された全体的計画の作成が困難な状況にあることを確認した。続いて，保育の目標・ねらい・内容の連関性を確保する上で，そのことを可能にする保育者の振り返りの仕方が不可欠となることを踏まえて，幼稚園の保育全体に関する文部科学省公表資料に示されている，保育者の振り返りの目的，観点，方法を抽出し整理し，検討した。その結果，保育者の長期の振り返りに関して示されている記述では，具体性が乏しく，保育の目標・ねらい・内容の連関性の確保された長期指導計画及び全体的計画を作成する上で，実用的ではないことを明らかにした。 en-copyright= kn-copyright= en-aut-name=ARITASho en-aut-sei=ARITA en-aut-mei=Sho kn-aut-name=有田翔 kn-aut-sei=有田 kn-aut-mei=翔 aut-affil-num=1 ORCID= en-aut-name=YOKOMATSUTomoyoshi en-aut-sei=YOKOMATSU en-aut-mei=Tomoyoshi kn-aut-name=横松友義 kn-aut-sei=横松 kn-aut-mei=友義 aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Education, Okayama University (Master’s Course) kn-affil=岡山大学大学院教育学研究科大学院生 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=保育者の振り返り (reflections of early care and education practitioners) kn-keyword=保育者の振り返り (reflections of early care and education practitioners) en-keyword=幼稚園 (kindergarten) kn-keyword=幼稚園 (kindergarten) en-keyword=カリキュラム・マネジメント (curriculum management) kn-keyword=カリキュラム・マネジメント (curriculum management) en-keyword=文部科学省公表資料 (the content on the care and education of kindergarten children published by Japan’s Ministry of Education, Culture, Sports, Science and Technology) kn-keyword=文部科学省公表資料 (the content on the care and education of kindergarten children published by Japan’s Ministry of Education, Culture, Sports, Science and Technology) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=75 end-page=89 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Trends in Awareness of Earthquake Disaster Prevention among Students Aspiring to Become Childcare Providers kn-title=保育者志望学生の地震防災に対する意識の傾向 en-subtitle= kn-subtitle= en-abstract=　In recent years, under the growing sense of crisis about the possibility of a major earthquake in the Nankai Trough, etc., it has become necessary to have more awareness of earthquake disaster prevention and to take measures for disaster prevention regularly. The purpose of this study was to clarify the actual situation of students who aspire to become childcare providers to protect children's lives. As a result of a questionnaire survey, we found that their awareness of the danger of earthquakes tended to differ by grade level and that their understanding and knowledge of earthquake disaster prevention differed depending on their awareness of earthquake disaster prevention. In the future, it will be necessary to consider conducting evacuation drills in kindergartens or nursery schools and providing guidance on disaster prevention education in training programs for childcare providers. kn-abstract=　近年，南海トラフ巨大地震や都市直下型地震に対する危機感が高まる中，地震防災に対する高い意識を持ち，普段から防災に関する取り組みに努めることが求められている。本研究では，子どもの命を守る保育者を目指す志望学生が，地震災害に対する意識をどのように持ち，地震防災に関する知識や理解をどの程度保持しているのかについて，その実態を明らかにすることを目的とした。保育者養成校４大学の学生に対する質問紙調査を行った結果，地震への危機意識が学年によって異なる傾向にあることや，地震防災に関する意識の高低によって，地震に対する知識や認識の違いがあることが判明した。今後，幼児教育・保育施設における避難訓練の実施や，保育者養成課程において防災教育に関する指導を検討していくことが求められる。 en-copyright= kn-copyright= en-aut-name=SATOHDaisuke en-aut-sei=SATOH en-aut-mei=Daisuke kn-aut-name=佐藤大介 kn-aut-sei=佐藤 kn-aut-mei=大介 aut-affil-num=1 ORCID= en-aut-name=TAKAHASHIKei en-aut-sei=TAKAHASHI en-aut-mei=Kei kn-aut-name=髙橋慧 kn-aut-sei=髙橋 kn-aut-mei=慧 aut-affil-num=2 ORCID= en-aut-name=BABANoriko en-aut-sei=BABA en-aut-mei=Noriko kn-aut-name=馬場訓子 kn-aut-sei=馬場 kn-aut-mei=訓子 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Health and Welfare, Kawasaki University of Medical Welfare kn-affil=川崎医療福祉大学医療福祉学部 affil-num=2 en-affil=Faculty of Childhood Education, Kurashiki Sakuyo University kn-affil=くらしき作陽大学子ども教育学部 affil-num=3 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=地震防災 (earthquake disaster prevention) kn-keyword=地震防災 (earthquake disaster prevention) en-keyword=保育者志望学生 (students aspiring to become childcare providers) kn-keyword=保育者志望学生 (students aspiring to become childcare providers) en-keyword=意識調査 (questionnaire survey) kn-keyword=意識調査 (questionnaire survey) en-keyword=危機意識 (sense of crisis) kn-keyword=危機意識 (sense of crisis) en-keyword=地震防災教育 (education for earthquake disaster prevention) kn-keyword=地震防災教育 (education for earthquake disaster prevention) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=59 end-page=73 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of Career Years on the Coordination Behavior of Yogo Teachers kn-title=養護教諭のコーディネーション行動に及ぼすキャリア年数の影響 en-subtitle= kn-subtitle= en-abstract=The purpose of this study was to clarify the factors influencing coordination behavior of Yogo teachers and the relationship between the occurrence process of the factors and career years. The subjects analyzed were 695 persons working in public elementary and junior high schools. The effect of years of career was seen in the improvement of scale scores of factors related to the stages of coordination behavior and motivation, as well as subscale scores of the factors.
The relationship between the number of years of career and factors related to the generation process of coordination behavior suggested three characteristics. That is, (1) The establishment of a foundation for organizational support that starts from collaboration, due to the correlation between factors showing high subscale scores unaffected by the number of years of career, and (2) The correlation among factors of motivational factors whose subscale scores increase with the number of years of career, which leads to the promotion of individualized support efforts, and (3) Correlation between factors of leader recognition and individual support seen in the career category of 11 years or more, and which leads to the promotion of expansion to management of organizational support. kn-abstract=　本研究の目的は，養護教諭のコーディネーション行動に影響する要因やその因子の傾向をキャリア年数から捉え，これらとコーディネーション行動の生起プロセスとの関係について明らかにすることであった。分析対象は，公立小学校・中学校勤務695名とした。キャリア年数の影響は，コーディネーション行動と動機づけの段階に関わる要因の尺度得点や，因子の下位尺度得点の向上に見られた。また，キャリア年数とコーディネーション行動の生起プロセスに関わる因子間の関係からは，（1）キャリア年数に影響されない高い下位尺度得点を示す因子間相関による，協働を起点にした組織支援の基盤づくり，（2）キャリア年数により下位尺度得点が高まる動機づけ要因の因子間相関による，個別支援の取組推進へのつながり，（3）11年以上キャリア区分で見られるリーダー認知と個別支援の因子間相関，及び組織的支援のマネジメントへの広がり，の３つの特徴をもつことが示唆された。 en-copyright= kn-copyright= en-aut-name=SUZUKIKaoru en-aut-sei=SUZUKI en-aut-mei=Kaoru kn-aut-name=鈴木薫 kn-aut-sei=鈴木 kn-aut-mei=薫 aut-affil-num=1 ORCID= en-aut-name=MIMURAYukari en-aut-sei=MIMURA en-aut-mei=Yukari kn-aut-name=三村由香里 kn-aut-sei=三村 kn-aut-mei=由香里 aut-affil-num=2 ORCID= affil-num=1 en-affil=Research student, United Graduate School of Education, Hyogo University of Teacher Education kn-affil=兵庫教育大学連合大学院教育学研究科研究生 affil-num=2 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=養護教諭 (Yogo teacher) kn-keyword=養護教諭 (Yogo teacher) en-keyword=コーディネーション行動 (coordination behavior) kn-keyword=コーディネーション行動 (coordination behavior) en-keyword=尺度得点 (scale score) kn-keyword=尺度得点 (scale score) en-keyword=下位尺度得点 (subscale scoreｒ) kn-keyword=下位尺度得点 (subscale scoreｒ) en-keyword=行動の生起プロセス (process of behavioral development) kn-keyword=行動の生起プロセス (process of behavioral development) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=45 end-page=58 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Childcare and Support in Nursery Schools for the Development of Geometry and Number Sense for Five-Year-Old Children kn-title=５歳児を対象とした数量・図形感覚を育む保育所保育の実際と援助の在り方 en-subtitle= kn-subtitle= en-abstract=This study focuses on “the interest and sense of numbers, geometry, and words”, which is regarded as one of "the Ideal Image by the End of Childhood". The focus is on 5-year-old pre-schoolers and their experiences with numbers and shapes in daily lives and games at nursery schools with a comparison with the mathematics classes in the first grade of elementary school. We also aim to provide insights for nursery schools on how to arouse children’s interest and support them to get familiar with geometry and numbers through games.
Our finding reveals that children naturally become familiar with geometry and numbers in their daily lives and their experiences become the foundation when they cope with elementary school mathematics. We also come to know that nursery teachers have to visualize the connection between their games with elementary school mathematics and actively arouse children’s interests and understanding. kn-abstract=　本研究では、幼児期の終わりまでに育って欲しい10の姿のひとつである、「数量・図形、文字等への関心・感覚」に着目し、就学前の５歳児に焦点を当て、保育所の日常生活や遊びにおいて子どもがどのような数量・図形に関する事柄を経験しているのか、また、その経験を小学校１年生の算数科の学習内容と照らして検討した。さらに、子どもが園生活や遊びの中で数量・図形に関心をもって親しみ、学びを得ることを支える保育の在り方について検討した。
　その結果、子どもは日常の中で主体的に数量・図形に親しむ経験をすると共に、その経験が小学校算数科の内容に連続する学びの基礎となっていることが明らかになった。また、保育士自身が小学校算数との繋がりを見通しながら、眼前の子どもの興味や関心に沿って援助することが専門的力量として求められることが示唆された。 en-copyright= kn-copyright= en-aut-name=SUZUKIFuka en-aut-sei=SUZUKI en-aut-mei=Fuka kn-aut-name=鈴木楓花 kn-aut-sei=鈴木 kn-aut-mei=楓花 aut-affil-num=1 ORCID= en-aut-name=KATAYAMAMika en-aut-sei=KATAYAMA en-aut-mei=Mika kn-aut-name=片山美香 kn-aut-sei=片山 kn-aut-mei=美香 aut-affil-num=2 ORCID= affil-num=1 en-affil=Mitsu Kanagawa Certified childcare center kn-affil=岡山市御津金川認定こども園 affil-num=2 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 幼児教育講座 en-keyword=10 の姿 kn-keyword=10 の姿 en-keyword=数量・図形 kn-keyword=数量・図形 en-keyword=保育士 kn-keyword=保育士 en-keyword=専門的力量 kn-keyword=専門的力量 en-keyword=小学校算数科 kn-keyword=小学校算数科 en-keyword=the Ideal Image by the End of Childhood kn-keyword=the Ideal Image by the End of Childhood en-keyword=numbers & geometry kn-keyword=numbers & geometry en-keyword=professional nursery school teachers kn-keyword=professional nursery school teachers en-keyword=elementary school kn-keyword=elementary school en-keyword=mathematics kn-keyword=mathematics END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=33 end-page=44 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Systematic Improvement of Lessons in Elementary Schools –A Case Study of Japanese Language Instruction Aimed at Realizing the “Ideal Child Image”– kn-title=小学校における組織的な授業改善のあり方　〜「目指す子ども像」実現に向けた国語科指導を事例として〜 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究の目的は、「目指す子ども像」実現に向けた国語科の授業づくりの具体を検討し、小学校における組織的な授業改善のあり方を提言することにある。具体的には、「目指す子ども像」実現に向けた国語科の授業づくりを通して、今の社会が小学校教育に求める特色ある授業づくりの進め方を明らかにするため、勤務校である早島町立早島小学校に所属する教師の授業づくりを対象に事例研究を展開した。検討を通じて明らかになったことは、授業づくりにおける教師の思考・実践過程と、これらを実践者が反省的に捉え直すための「目指す子ども像」による言語活動具体化の手立てである。さらに、授業づくりの組織・系統性は、他学年教師の役割によってもたらされることが確認されたことから、それらを踏まえつつ、「目指す子ども像」実現に向けた授業づくりのあり方を体系化した。そうすることで、小学校における組織的な授業改善を進めていくための可能性が見出された。 en-copyright= kn-copyright= en-aut-name=KOMOTOAkihiro en-aut-sei=KOMOTO en-aut-mei=Akihiro kn-aut-name=河本章宏 kn-aut-sei=河本 kn-aut-mei=章宏 aut-affil-num=1 ORCID= en-aut-name=MIYAMOTOKoji en-aut-sei=MIYAMOTO en-aut-mei=Koji kn-aut-name=宮本浩治 kn-aut-sei=宮本 kn-aut-mei=浩治 aut-affil-num=2 ORCID= en-aut-name=IKEDAMasafumi en-aut-sei=IKEDA en-aut-mei=Masafumi kn-aut-name=池田匡史 kn-aut-sei=池田 kn-aut-mei=匡史 aut-affil-num=3 ORCID= en-aut-name=MATUDASatoshi en-aut-sei=MATUDA en-aut-mei=Satoshi kn-aut-name=松田聡 kn-aut-sei=松田 kn-aut-mei=聡 aut-affil-num=4 ORCID= affil-num=1 en-affil=Hayashima Elementary School (Graduate School of Education (Professional Degree Corse), Okayama University) kn-affil=岡山大学大学院教育学研究科大学院生 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=3 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=4 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=目指す子ども像 (The school's educational goals) kn-keyword=目指す子ども像 (The school's educational goals) en-keyword=価値目標 (into value-objectives) kn-keyword=価値目標 (into value-objectives) en-keyword=国語学力 (Japanese language ability) kn-keyword=国語学力 (Japanese language ability) en-keyword=カリキュラムマネジメント (Curriculum Management) kn-keyword=カリキュラムマネジメント (Curriculum Management) en-keyword=組織・系統性 (Organization and Systematic) kn-keyword=組織・系統性 (Organization and Systematic) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=17 end-page=31 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Research of the Image of Teacher-Training Courses among Student Teachers in Non-Faculty of Education kn-title=全学教職課程履修学生の教職課程イメージに関する研究 en-subtitle= kn-subtitle= en-abstract=The purpose of this study was to explore the image of teacher-training courses among student teachers in non-faculty of education. In this study, special attention to was paid to the difference first-year students and fourth-year students. This study 1 included student teachers in non-faculty of education. They were asked to answer metaphor-making task : “teacher-training courses”. Major findings (study 1) were as follows: (a) analysis of metaphors and reasons regarding the image of teacher-training course revealed 19 categories. (b) The category with the most number of descriptions was “A place to learn to become a teacher” followed by “A place to grow as a person”. (c) There were differences in the number of descriptions in some categories between first-year students and fourth-year students. Next, major findings (study 2) were as follows: (a) Exploratory factor analysis of the concept of image of teacher-training courses revealed 11 factors such as “place for active learning” and “hard”. (b) First-year students and fourth-year students had different scores on three factors: “Opportunity to reflect on the educational experience”, “Great value” and “A place for longterm leaning”. These studies indicated that student teachers in non-faculty of education had various images teacher-training courses, and that there were differences in some images teacher-training course between first-year students and fourth-year students. kn-abstract=　本研究の目的は，全学教職課程履修学生の教職課程イメージを検討することであった。研究１ではメタファー法を用いて全学教職課程履修学生を対象に教職課程イメージを調査し，19のカテゴリーが得られた。最も記述が多いカテゴリーは「教師になるための学びの場」であり，次いで「人としての成長の場」であった。また，1年生と4年生でいくつかのカテゴリーで有意差が見られた。研究２では，研究１を基に教職課程イメージを測定する尺度作成を試みると共に，1年生と4年生での比較を行った。調査の結果，教職課程イメージは「能動的な学びの場」「大変さ」など全11因子からなること，「被教育体験の振り返りの機会」「お得感」「長期的な学びの場」において1年生と4年生で有意差があること，が示唆された。本研究から全学教職課程履修学生の教職課程イメージの一端が明らかにされると共に，1年生と4年生で有しているイメージが部分的に異なる可能性が示唆された。 en-copyright= kn-copyright= en-aut-name=MISHIMATomotaka en-aut-sei=MISHIMA en-aut-mei=Tomotaka kn-aut-name=三島知剛 kn-aut-sei=三島 kn-aut-mei=知剛 aut-affil-num=1 ORCID= affil-num=1 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター en-keyword=全学教職課程履修学生 (student teachers in non-faculty of education) kn-keyword=全学教職課程履修学生 (student teachers in non-faculty of education) en-keyword=教職課程イメージ (image of teacher-training courses) kn-keyword=教職課程イメージ (image of teacher-training courses) en-keyword=メタファー (metaphor) kn-keyword=メタファー (metaphor) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=1 end-page=15 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Treatment of Learning about Marriage in High School Home Economics (2): Description Analysis of the Textbooks kn-title=高等学校家庭科における結婚に関する学習の扱い（2）　教科書の記述分析に基づいて en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿では，「多様化する結婚」という日本の現状を踏まえ，結婚に関連する学習内容が，高等学校家庭科においてどのように扱われているかを分析することを目的とし，平成30年版の『高等学校学習指導要領』に基づいて構成された「家庭基礎」の教科書10冊を用いて結婚に関連する学習内容を分析した。分析の結果，教科書には，『指導要領』に基づいて結婚等に関連する法制度の記述がみられること，結婚をめぐる現状や変化を反映した学習内容が取り扱われていることを確認した。また，夫婦の氏，同性婚を取り上げ，具体的な学習活動について分析した結果，教科書によっては，知識や現状を提示する学習だけでなく，学習者である高校生が自ら考えること，選択すること，さらに他人の選択についても客観的に考えられるように問いかけている教科書もみられた。結婚に関連する法律，語句の掲載の有無，学習活動において，教科書によって取扱いの差があることが明らかになった。 en-copyright= kn-copyright= en-aut-name=TANABEShiho en-aut-sei=TANABE en-aut-mei=Shiho kn-aut-name=田邉詩歩 kn-aut-sei=田邉 kn-aut-mei=詩歩 aut-affil-num=1 ORCID= en-aut-name=LEEKyoungwon en-aut-sei=LEE en-aut-mei=Kyoungwon kn-aut-name=李璟媛 kn-aut-sei=李 kn-aut-mei=璟媛 aut-affil-num=2 ORCID= affil-num=1 en-affil=Fukuyama University kn-affil=福山大学 affil-num=2 en-affil=Faculty of Education，Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=高等学校家庭科 (High School Home Economics) kn-keyword=高等学校家庭科 (High School Home Economics) en-keyword=教科書 (Textbooks) kn-keyword=教科書 (Textbooks) en-keyword=結婚 (Marriage) kn-keyword=結婚 (Marriage) en-keyword=多様化する結婚 kn-keyword=多様化する結婚 en-keyword=Course of Study kn-keyword=Course of Study END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=表紙・目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=岡山大学教師教育開発センター紀要 第15号 全文（一括ダウンロード用） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=8502 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250312 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Age-specific assessment of initial hemoglobin levels and shock index for predicting life-saving interventions in pediatric blunt liver and spleen injuries en-subtitle= kn-subtitle= en-abstract= kn-abstract=This study aimed to evaluate the effectiveness of combining initial hemoglobin levels with the shock index for predicting the need for life-saving interventions (LSI) in pediatric patients with blunt liver and spleen injuries (BLSI), specifically tailored to different age groups. This was a multicenter retrospective cohort study of pediatric patients with BLSI in Japan. The area under the receiver operating characteristic curve (AUROC) were used to assess predictive accuracy. The study included 1,370 patients. LSI was required in 59 of 247 (23.9%) aged 1 to 6 years, 100 of 402 (24.9%) aged 7 to 12 years, and 125 of 297 (42.1%) patients aged 13 to 16 years. Within each specific age group, the predictability was categorized as fair and appeared higher than that of the entire cohort or when using either parameter alone. Notably, in the 1 to 6-year age group, the combined values showed the highest predictability, which was statistically superior to the shock index alone (AUROC of 0.770 vs. 0.671, P = 0.025). Tailoring initial hemoglobin levels and shock index to specific age groups enhances predictability of LSI in pediatric BLSI, showing a fair level of predictive accuracy. en-copyright= kn-copyright= en-aut-name=YumotoTetsuya en-aut-sei=Yumoto en-aut-mei=Tetsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ObaraTakafumi en-aut-sei=Obara en-aut-mei=Takafumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HongoTakashi en-aut-sei=Hongo en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=IidaAtsuyoshi en-aut-sei=Iida en-aut-mei=Atsuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TsukaharaKohei en-aut-sei=Tsukahara en-aut-mei=Kohei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KatsuraMorihiro en-aut-sei=Katsura en-aut-mei=Morihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KondoYutaka en-aut-sei=Kondo en-aut-mei=Yutaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=YasudaHideto en-aut-sei=Yasuda en-aut-mei=Hideto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KushimotoShigeki en-aut-sei=Kushimoto en-aut-mei=Shigeki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=YorifujiTakashi en-aut-sei=Yorifuji en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=NaitoHiromichi en-aut-sei=Naito en-aut-mei=Hiromichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=NakaoAtsunori en-aut-sei=Nakao en-aut-mei=Atsunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=SHIPPs Study Group en-aut-sei=SHIPPs Study Group en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= affil-num=1 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=6 en-affil=Department of Surgery, Okinawa Chubu Hospital kn-affil= affil-num=7 en-affil=Department of Emergency and Critical Care Medicine, Juntendo University Urayasu Hospital kn-affil= affil-num=8 en-affil=Department of Emergency and Critical Care Medicine, Jichi Medical University Saitama Medical Center kn-affil= affil-num=9 en-affil=Division of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine kn-affil= affil-num=10 en-affil=Department of Epidemiology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=11 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=12 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=13 en-affil= kn-affil= en-keyword=Abdominal injuries kn-keyword=Abdominal injuries en-keyword=Blood transfusions kn-keyword=Blood transfusions en-keyword=Hemoglobin kn-keyword=Hemoglobin en-keyword=Hemostasis kn-keyword=Hemostasis en-keyword=Shock index kn-keyword=Shock index END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=裏表紙・英文目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=奥付 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=81 end-page=94 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Building a Task Bank to Enhance Task-Supported Language Teaching : Tailoring Task Difficulty to Match Proficiency Levels of Japanese Language Learners kn-title=タスク支援型指導を支援するタスク・バンクの構築を目指して―日本語学習者の習熟度に合わせたタスクの難易度調整― en-subtitle= kn-subtitle= en-abstract=This paper reports on the creation and practice of using tasks for task-supported language teaching (TSLT). While focusing on TSLT, in which tasks are incorporated into the existing curriculum as a supplement, the aim is to construct a task bank to support the transition from PPP (Presentation-Practice-Production) classes to TSLT. The results of the analysis on the changes in utterances during tasks with different levels of difficulty showed that (1) the number of utterances did not increase in proportion to the number of items (elements or information) included in the task, (2) tasks with more items and higher difficulty increased the range of expressions used by Japanese learners, and (3) the goal of the task presented in the role card made it possible to predict the intention of the utterance, leading to a tendency to tolerate inaccurate utterances. kn-abstract=本稿では，タスク支援型指導（TSLT）用のタスクの作成およびタスクを用いた実践について報告する。既存のカリキュラムの中にタスクを補助的に取り入れるTSLTに着目し，PPP（Presentation-Practice-Production）授業からTSLTへの移行を支援するタスク・バンクの構築を目指し，初級日本語教科書のエクササイズをベースに，同じトピックで難易度の異なるタスクの作成を行った。難易度の違いによるタスク中の発話の変化を分析した結果，（1）発話数についてはタスクに含まれる項目数（要素や情報の数）の増加に比例して増えるわけではないこと，（2）項目数が多い難易度が高いタスクでは，日本語学習者の表現の使用幅が広がること，（3）タスクのゴールがロールカードにて提示されていることにより，発話意図の予測が可能になり，不正確な発話が許容される傾向があることが示された。 en-copyright= kn-copyright= en-aut-name=SUESHIGEMiwa en-aut-sei=SUESHIGE en-aut-mei=Miwa kn-aut-name=末繁美和 kn-aut-sei=末繁 kn-aut-mei=美和 aut-affil-num=1 ORCID= affil-num=1 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 en-keyword=PPP kn-keyword=PPP en-keyword=TSLT kn-keyword=TSLT en-keyword=タスク kn-keyword=タスク en-keyword=項目数 kn-keyword=項目数 en-keyword=難易度調整 kn-keyword=難易度調整 END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=71 end-page=80 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=KIBITANGO : Development and Implementation of an Academic English Vocabulary Learning Program kn-title=きびたんご ―アカデミック英単語学習プログラムの開発と実践報告― en-subtitle= kn-subtitle= en-abstract=At Okayama University, we have developed and provided a self-study material called "Kibitango" to help students improve their academic English vocabulary. The project began in 2019, with a focus on collecting frequently used words from academic journals, resulting in a list of 1,500 words. Each word comes with explanations by project members and examples of how it is used in academic papers. The material has been available to students since the 2022 academic year. Registered students receive one word per day via email and learn through the Kibitango website. The number of users has steadily increased. Today, however, several challenges have emerged, including the need to update the word list and improve the delivery method and system. kn-abstract=岡山大学では学術英語の語彙力を伸ばすための自習教材として、「きびたんご」を開発し学生に提供している。2019年から開発のためのプロジェクトを開始し、学術雑誌から頻出単語を収集し1500語のリストを作成した。単語には意味・発音などの基礎情報以外に、プロジェクトメンバーによる解説や実際にどのように学術論文中に使用されているかの実例を付している。学生への提供は2022年度からで、登録した学生にメールで一日一単語配信し、専用ウェッブサイトで学習させるというシステムである。利用者も順調に増えている。開発開始から５年、提供から２年経過し、単語リストのアップデートや提供方法・システムの改善など課題も明らかになっている。 en-copyright= kn-copyright= en-aut-name=IGARASHIMasumi en-aut-sei=IGARASHI en-aut-mei=Masumi kn-aut-name=五十嵐潤美 kn-aut-sei=五十嵐 kn-aut-mei=潤美 aut-affil-num=1 ORCID= en-aut-name=OGINOMasaru en-aut-sei=OGINO en-aut-mei=Masaru kn-aut-name=荻野勝 kn-aut-sei=荻野 kn-aut-mei=勝 aut-affil-num=2 ORCID= en-aut-name=OTOSHIJunko en-aut-sei=OTOSHI en-aut-mei=Junko kn-aut-name=大年順子 kn-aut-sei=大年 kn-aut-mei=順子 aut-affil-num=3 ORCID= en-aut-name=TERANISHIMasako en-aut-sei=TERANISHI en-aut-mei=Masako kn-aut-name=寺西雅子 kn-aut-sei=寺西 kn-aut-mei=雅子 aut-affil-num=4 ORCID= en-aut-name=YOSHIDAAzumi en-aut-sei=YOSHIDA en-aut-mei=Azumi kn-aut-name=吉田安曇 kn-aut-sei=吉田 kn-aut-mei=安曇 aut-affil-num=5 ORCID= en-aut-name=KENMOTSUYoshi en-aut-sei=KENMOTSU en-aut-mei=Yoshi kn-aut-name=剱持淑 kn-aut-sei=剱持 kn-aut-mei=淑 aut-affil-num=6 ORCID= affil-num=1 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 affil-num=2 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 affil-num=3 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 affil-num=4 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 affil-num=5 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 affil-num=6 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 en-keyword=学術語彙 kn-keyword=学術語彙 en-keyword=英語語彙力 kn-keyword=英語語彙力 en-keyword=自習教材 kn-keyword=自習教材 en-keyword=教材開発 kn-keyword=教材開発 END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=49 end-page=70 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Online Exchange Program between Sungkyunkwan University,Jilin University,and Okayama University : Practice Report kn-title=成均館・吉林大学交流プログラム【オンライン】実践報告 en-subtitle= kn-subtitle= en-abstract=The Institute for Promotion of Education and Campus Life at Okayama University hosted 5th annual Sungkyunkwan University (South Korea) and Jilin University (China) Exchange Program online. This program convened Sungkyunkwan University students, Jilin University students, and Okayama University students to engage in discussion, exploration, and presentation of cultural topics. While participants used Japanese as their common language, they addressed and overcame communication challenges that arise due to language barriers and cultural differences. The current report explores the program’s significance for global citizenship education, program’s results, several issues encountered during its implementation, and actions to resolve those issues. kn-abstract=岡山大学教育推進機構初修外国語系が毎年２月にオンラインで実施している「成均館・吉 林大学交流プログラム」は、日中韓三ヵ国の大学の学生が、日本語を共通言語として、複 数の文化・言語、学習言語と母語の違いなどを包摂した場で生じるコミュニケーション上 の問題を解決しながら、様々な話題のディスカッションやプレゼンテーションを行なう。 本実践報告は、このプログラムの趣旨と成果、また実践に当たっての様々な課題とそれに 対する取り組みについて報告し、コロナ後の国際交流の一つのモデルとなることを期待す るものである。 en-copyright= kn-copyright= en-aut-name=FUJIWARAYuko en-aut-sei=FUJIWARA en-aut-mei=Yuko kn-aut-name=藤原祐子 kn-aut-sei=藤原 kn-aut-mei=祐子 aut-affil-num=1 ORCID= en-aut-name=AKITASetsuko en-aut-sei=AKITA en-aut-mei=Setsuko kn-aut-name=秋田節子 kn-aut-sei=秋田 kn-aut-mei=節子 aut-affil-num=2 ORCID= en-aut-name=ISHIITomomi en-aut-sei=ISHII en-aut-mei=Tomomi kn-aut-name=石井友美 kn-aut-sei=石井 kn-aut-mei=友美 aut-affil-num=3 ORCID= en-aut-name=SATOMiho en-aut-sei=SATO en-aut-mei=Miho kn-aut-name=佐藤美穂 kn-aut-sei=佐藤 kn-aut-mei=美穂 aut-affil-num=4 ORCID= affil-num=1 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 affil-num=2 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学非常勤講師 affil-num=3 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 affil-num=4 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学非常勤講師 en-keyword=三国間交流 kn-keyword=三国間交流 en-keyword=異文化理解 kn-keyword=異文化理解 en-keyword=複言語・複文化主義 kn-keyword=複言語・複文化主義 en-keyword=インクルージョン kn-keyword=インクルージョン en-keyword=アクティブラーニング kn-keyword=アクティブラーニング END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=33 end-page=48 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Old Stories, Original Retellings : The Heike-related Tales in the Repertory of the Blind Biwa Players of Kyushu en-subtitle= kn-subtitle= en-abstract= kn-abstract=While higobiwa, the blind biwa players' tradition of Kyushu, is regarded as a historically distinctive genre, its evolution has been influenced by interactions with other storytelling traditions. It is evident that higobiwa borrowed stories from other genres and adapted them to its own distinctive narrative style. The findings of this research focused on the Heike-related tales reveal significant similarities between the tales of Ichi-no-Tani and Ko-Atsumori in the blind biwa players' tradition and Ko-Atsumori in the kojoruri tradition. These parallels suggest a shared narrative lineage between these two performance genres, prompting a reevaluation of our understanding of the transmission and evolution of oral narratives within the blind biwa players' tradition of Kyushu and shedding light on the dynamic nature and the interconnectedness of different performance traditions within Japan. en-copyright= kn-copyright= en-aut-name=KHALMIRZAEVASaida en-aut-sei=KHALMIRZAEVA en-aut-mei=Saida kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Institute of Global Human Resource Development, Okayama University kn-affil= en-keyword=higobiwa kn-keyword=higobiwa en-keyword=the blind biwa players' tradition kn-keyword=the blind biwa players' tradition en-keyword=kojoruri kn-keyword=kojoruri en-keyword=Ichi-no-Tani kn-keyword=Ichi-no-Tani en-keyword=Ko-Atsumori kn-keyword=Ko-Atsumori END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=13 end-page=32 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Research on Factors Promoting Study in Japan : Cases of International Students from South-East Asia kn-title=日本への留学を促進する要因に関する研究　－東南アジアからの留学生を事例として－ en-subtitle= kn-subtitle= en-abstract=In this study, international students from Southeast Asia were asked, 'Why did you decide to study in Japan?' and the information was collected through semi-structured interviews. The results showed that (i) international students' image of Japan, (ii) parents' image of Japan, (iii) the availability of scholarships, (iv) affordable tuition fees and living costs, and (v) the existence of a community of people from the country of origin., were found to be important. It was assumed that some of this information and image is formed by the international students' (1) satisfaction with their study destination, (2) opportunities to interact with Japanese people, (3) ease of living in Japan, (4) Japanese language level, (5) understanding of Japanese culture, etc., and is reinforced through word of mouth and the internet. Therefore, supporting the creation of these environments will create a positive image of studying in Japan and increase the number of students from Southeast Asia. kn-abstract=　本研究では、東南アジアから留学している留学生15人を対象として「なぜ日本に留学したのか？」、半構造化インタビューにより情報を収集した。その結果、(i) 留学生の日本に対するイメージ、(ii) 保護者の日本に対するイメージ、(iii) 奨学金の機会、(iv) 私費留学が可能な学費・生活費レベル、(v) 出身国コミュニティーの有無、が重要であることが分かった。これらの情報やイメージの一部は、(1) 留学先での満足度、(2) 日本人との交流機会、(3) 生活のしやすさ、(4) 留学生の日本語レベル、(5) 日本文化に対する理解等によって形成され、ロコミやインターネットを通じて強化されることが推測された。よって、上記の項目に着目し、留学生の満足度等を向上させるための環境づくりを支援していくことが、日本留学に対するプラスのイメージを作り、東南アジアからの留学生増につながっていくと考えられた。 en-copyright= kn-copyright= en-aut-name=INAMORITakao en-aut-sei=INAMORI en-aut-mei=Takao kn-aut-name=稲森岳央 kn-aut-sei=稲森 kn-aut-mei=岳央 aut-affil-num=1 ORCID= affil-num=1 en-affil=Institute of Global Human Resource Development, Okayama University kn-affil=岡山大学グローバル人材育成院 en-keyword=日本留学 kn-keyword=日本留学 en-keyword=留学生 kn-keyword=留学生 en-keyword=東南アジア kn-keyword=東南アジア en-keyword=ASEAN kn-keyword=ASEAN en-keyword=促進要因 kn-keyword=促進要因 END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=1 end-page=12 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relationship between Sexual Minorities and Attention Deficit Hyperactivity Disorder (ADHD) kn-title=セクシュアルマイノリティと発達障害のADHD特性との関連 en-subtitle= kn-subtitle= en-abstract=To reveal the association between various sexual minority groups and the developmental disorder (ADHD), a web-based survey was conducted. Adults aged 18 years and over were surveyed and 11018 people (mean age 39.47 years) responded. The Adult ADHD Self-Rating Scale was used. For each sexual minority, a t-test was performed for ADHD scores and subscale scores of “inattention,” “hyperactivity,” and “impulsivity,” and a x2 test was performed for the number of persons above the cut-off. All sexual minority groups had significantly higher ADHD and subscale scores and significantly more people above the cut-off scores, so the close association was evident. There was no significant difference in ADHD scores or numbers of persons between transwomen and transmen. kn-abstract=　様々なセクシュアルマイノリティと発達障害のADHD（Attention Deficit Hyperactivity Disorder）との関連を明らかにするため， WEB調査を行った。18歳以上の成人を対象とし，11,018人（平均年39.47歳）から回答を得た。ADHDを測る質問紙は「成人期ADHD検査（A-ADHD）」を使用した。セクシュアルマイノリティごとに， ADHD得点と下位尺度「不注意」「多動性」「衝動性」得点についてt検定，カットオフ54点以上の人数についてx2検定を行った。全てのセクシュアルマイノリティで有意にADHDと下位尺度得点が高く，カットオフ得点以上の人数も有意に多かった。なおトランスウーマンとトランスマンでADHD得点や人数に有意な差は見られなかった。以上から，セクシュアルマイノリティとADHDは密接に関係している事が明らかとなった。 en-copyright= kn-copyright= en-aut-name=MATSUIMegumi en-aut-sei=MATSUI en-aut-mei=Megumi kn-aut-name=松井めぐみ kn-aut-sei=松井 kn-aut-mei=めぐみ aut-affil-num=1 ORCID= affil-num=1 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 en-keyword=セクシュアルマイノリティ kn-keyword=セクシュアルマイノリティ en-keyword=発達障害 kn-keyword=発達障害 en-keyword=ADHD kn-keyword=ADHD en-keyword=注意欠如・多動症 kn-keyword=注意欠如・多動症 END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=表紙・目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=195 cd-vols= no-issue= article-no= start-page=123743 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202503 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Utility of Surgical Simulation for Tubular Retractor Surgery Using Three-Dimensional Printed Intraventricular Tumor Models: Case Series en-subtitle= kn-subtitle= en-abstract= kn-abstract=Objective: The utility of the tubular retractor for deep-seated tumors, including intraventricular tumors, has recently been reported. However, the surgical field’s depth and narrowness can lead to blind spots, and it is crucial to prevent damage to the cortex and white matter fibers in eloquent areas. Therefore, preoperative simulation is critical for tubular retractor surgery. In this study, we investigated the benefits of threedimensional (3D)-printed intraventricular tumor models for tubular retractor surgery.
Methods: Nine patients with intraventricular central neurocytoma who underwent tubular retractor surgery at our institution between March 2013 and August 2023 were retrospectively reviewed. Fusion images and 3D-printed intraventricular tumor models were developed from preoperative computed tomography (CT) and magnetic resonance imaging (MRI). The puncture points of the tubular retractor were simulated using fusion images and 3D-printed intraventricular tumor models by 11 neurosurgeons (3 experts in brain tumors, 2 experts in areas other than brain tumors, and 6 residents). The dispersion of puncture points among 8 neurosurgeons (excluding brain tumor experts) was compared in each simulation model.
Results: These cases were categorized into two groups based on the dispersion of puncture points simulated by fusion images. Puncture point dispersion was markedly smaller in all cases when using 3D-printed intraventricular tumor models compared to simulations solely based on fusion images.
Conclusions: In intraventricular tumor surgery using a tubular retractor, 3D-printed intraventricular tumor models proved more beneficial in preoperative simulation compared to fusion images. en-copyright= kn-copyright= en-aut-name=OmaeRyo en-aut-sei=Omae en-aut-mei=Ryo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KimuraRyu en-aut-sei=Kimura en-aut-mei=Ryu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OtaniYoshihiro en-aut-sei=Otani en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HarumaJun en-aut-sei=Haruma en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SaijoTomoya en-aut-sei=Saijo en-aut-mei=Tomoya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=FujitaJuntaro en-aut-sei=Fujita en-aut-mei=Juntaro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=NishigakiShohei en-aut-sei=Nishigaki en-aut-mei=Shohei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=IkemachiRyosuke en-aut-sei=Ikemachi en-aut-mei=Ryosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=HiranoShuichiro en-aut-sei=Hirano en-aut-mei=Shuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=IshidaJoji en-aut-sei=Ishida en-aut-mei=Joji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=FujiiKentaro en-aut-sei=Fujii en-aut-mei=Kentaro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=YasuharaTakao en-aut-sei=Yasuhara en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=TanakaShota en-aut-sei=Tanaka en-aut-mei=Shota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= affil-num=1 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=10 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=11 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=12 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=13 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=3D-printed model kn-keyword=3D-printed model en-keyword=Case series kn-keyword=Case series en-keyword=Intraventricular tumors kn-keyword=Intraventricular tumors en-keyword=Preoperative surgical simulation kn-keyword=Preoperative surgical simulation en-keyword=Tubular retractor kn-keyword=Tubular retractor END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=5248 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250212 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Changes of leucine-rich alpha 2 glycoprotein could be a marker of changes of endoscopic and histologic activity of ulcerative colitis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Leucine-rich alpha 2 glycoprotein (LRG) is one of the serum biomarkers for disease activity of ulcerative colitis (UC). We focused on the correlation between the changes of LRG and the changes of endoscopic and histologic activity of UC, in comparison to the changes of fecal calprotectin (Fcal), fecal immunochemical test (FIT), and C-reactive protein (CRP). Seventy-nine patients with two or more colonoscopies were enrolled, and 123 paired colonoscopies and 121 paired biopsies were examined. With regard to the change of endoscopic/histologic activity between the preceding and subsequent colonoscopy, there was improvement (n = 29/45), unchanging (n = 63/36), and worsening (n = 31/40). The correlations between the changes of marker levels and endoscopic/histologic activity were Fcal; r = 0.50/0.39 and FIT; r = 0.41/0.40, LRG; r = 0.42/0.40 and CRP; r = 0.22/0.17. Furthermore, when the correlation between the changes of LRG levels and the changes of endoscopic/histological activity was compared with those of other markers, the correlation of LRG tended to be superior to those of CRP (CRP vs. LRG; p = 0.08/0.01). LRG is equivalent to fecal markers and superior to CRP, when inferring changes in disease activity of UC based on changes in its level. en-copyright= kn-copyright= en-aut-name=AoyamaYuki en-aut-sei=Aoyama en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HiraokaSakiko en-aut-sei=Hiraoka en-aut-mei=Sakiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YasutomiEriko en-aut-sei=Yasutomi en-aut-mei=Eriko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=InokuchiToshihiro en-aut-sei=Inokuchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TanakaTakehiro en-aut-sei=Tanaka en-aut-mei=Takehiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TakeiKensuke en-aut-sei=Takei en-aut-mei=Kensuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=IgawaShoko en-aut-sei=Igawa en-aut-mei=Shoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TakeuchiKeiko en-aut-sei=Takeuchi en-aut-mei=Keiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=TakaharaMasahiro en-aut-sei=Takahara en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=ToyosawaJunki en-aut-sei=Toyosawa en-aut-mei=Junki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=YamasakiYasushi en-aut-sei=Yamasaki en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=KinugasaHideaki en-aut-sei=Kinugasa en-aut-mei=Hideaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=KatoJun en-aut-sei=Kato en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=OkadaHiroyuki en-aut-sei=Okada en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=OtsukaMotoyuki en-aut-sei=Otsuka en-aut-mei=Motoyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= affil-num=1 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Pathology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= affil-num=6 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=7 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=8 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=9 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=10 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=11 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=12 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=13 en-affil=Department of Gastroenterology, Graduate School of Medicine, Chiba University kn-affil= affil-num=14 en-affil=Department of Gastroenterology, Japanese Red Cross Society Himeji Hospital kn-affil= affil-num=15 en-affil=Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Ulcerative colitis kn-keyword=Ulcerative colitis en-keyword=Leucine-rich alpha 2 glycoprotein kn-keyword=Leucine-rich alpha 2 glycoprotein en-keyword=Biomarker kn-keyword=Biomarker END start-ver=1.4 cd-journal=joma no-vol=128 cd-vols= no-issue= article-no= start-page=85 end-page=95 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Personal Networks and Social Support in Relation to Age of Elderly Women kn-title=高齢女性のパーソナル・ネットワークとソーシャル・サポートの年齢による違いについて en-subtitle= kn-subtitle= en-abstract= kn-abstract=　地方小都市である岡山県高梁市で1997年から1998年にかけて高齢女性を対象に調査をおこなった。本稿ではそのデータを分析し，年齢によって高齢女性のパーソナル・ネットワークとソーシャル・サポートの入手がどのように相違するかを検討した。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=高齢女性 kn-keyword=高齢女性 en-keyword=パーソナル・ネットワーク kn-keyword=パーソナル・ネットワーク en-keyword=ソーシャル・サポート kn-keyword=ソーシャル・サポート en-keyword=地方小都市 kn-keyword=地方小都市 END start-ver=1.4 cd-journal=joma no-vol=129 cd-vols= no-issue= article-no= start-page=45 end-page=53 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050715 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Daily Life and Life History of Elderly Women in Melbourne kn-title=メルボルンに住む高齢女性の暮らしとライフ・ヒストリー en-subtitle= kn-subtitle= en-abstract= kn-abstract=　メルボルンに住む3人の高齢女性に，①日常生活，②何に幸福を感じるか，③これまでの人生の3点に関して聞き取り調査を2004年9月におこなった。本稿では聞き取り調査の結果を提示し，それに考察を加えた。考察によって，次の4点を明らかにした。①子ども（夫婦）と頻繁に交際できない高齢女性は，代わりに，友人と頻繁に交際をしていた。そこで，社会関係には代替性があるといえる。② 3人の高齢女性は高い主観的幸福感を持っていた。これは，高齢女性が健康で，豊富な社会関係を保持していたからと考えられる。③大恐慌は，オーストラリア人の家族の生活に大なり小なり影響を及ぼしていた。④第二次世界大戦直後，オーストラリアでは専業主婦が一般的であった。 en-copyright= kn-copyright= en-aut-name=NOBEMasao en-aut-sei=NOBE en-aut-mei=Masao kn-aut-name=野邊政雄 kn-aut-sei=野邊 kn-aut-mei=政雄 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Social Studies Education, Faculty of Education, Okayama University kn-affil=岡山大学教育学部社会科教育講座 en-keyword=高齢女性 kn-keyword=高齢女性 en-keyword=メルボルン kn-keyword=メルボルン en-keyword=パーソナル・ネットワーク kn-keyword=パーソナル・ネットワーク en-keyword=主観的幸福感 kn-keyword=主観的幸福感 en-keyword=ライフ・ヒストリー kn-keyword=ライフ・ヒストリー END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=裏表紙・英文目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=奥付 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=123 end-page=127 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Review of Research on Digital Media Usage in Japanese Infancy kn-title=乳幼児期におけるデジタルメディア使用状況に関する研究の概観 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　子どものデジタルメディア，デジタルデバイスの使用に関して，使用開始年齢の低年齢化・長時間利用の問題が指摘され，乳幼児期からの使用実態の把握やそれが発達に及ぼす影響，および親の使用実態やペアレンタルコントロールも含めた検討の必要性が高まっているといえる。本報告では，近年の本邦における乳幼児を対象としたデジタルメディア，デジタルデバイスの使用実態を報告する研究や報告書を概観し，乳幼児期における使用実態の概要を把握するとともに，乳幼児期における依存傾向の実態やデジタルメディア使用に対する親の認識，乳幼児期のデジタルメディア使用をめぐるその他のトピックについて概観した。 en-copyright= kn-copyright= en-aut-name=MIYAKEMotoko en-aut-sei=MIYAKE en-aut-mei=Motoko kn-aut-name=三宅幹子 kn-aut-sei=三宅 kn-aut-mei=幹子 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=デジタルメディア kn-keyword=デジタルメディア en-keyword=デジタルデバイス kn-keyword=デジタルデバイス en-keyword=乳幼児期 kn-keyword=乳幼児期 en-keyword=ペアレンタルコントロール kn-keyword=ペアレンタルコントロール END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=115 end-page=121 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on the Transition and Interpretation of Yasuo Kuniyoshi’s Works within Japan kn-title=日本国内における国吉康雄作品の捉え方の変遷と解釈についての考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　洋画家・国吉康雄 (1889-1953) は、岡山市北区出石町に生まれ，日露戦争終結後の1906 年に労働移民として単身渡米し，アメリカの教育により画家としての才能を磨き，20 世紀前半のアメリカを代表する画家として評価される洋画家・国吉康雄（1889-1953）。本論では，その画業と作品評価について論じるわが国の研究者の記述を，作家の没後の1954 年に国立近代美術館（現国立東京近代美術館）で開催された「国吉康雄遺作展」を起点とし，20 世紀中に開催された主な展覧会と，2004 年に同じく東京国立近代美術館などで開催された「国吉康雄展」で確認した。結果，日本人による国吉作品の表現が，この1954 年時に決定づけられていることに，別の捉え方を提示されるまでに40 年の歳月を要していることが明らかとなった。 en-copyright= kn-copyright= en-aut-name=ITOShun en-aut-sei=ITO en-aut-mei=Shun kn-aut-name=伊藤駿 kn-aut-sei=伊藤 kn-aut-mei=駿 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Yasuo Kuniyoshi Studies : Art Education and Rural Reveitalization,Graduate School of Education, Okayama University kn-affil=岡山大学大学院教育学研究科国吉康雄記念・美術教育研究と地域創生講座 en-keyword=国吉康雄 kn-keyword=国吉康雄 en-keyword=作品解釈 kn-keyword=作品解釈 en-keyword=日系アメリカ人アーティスト kn-keyword=日系アメリカ人アーティスト en-keyword=展覧会 kn-keyword=展覧会 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=105 end-page=114 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Reconsidering Students’ Views of Home Economics through Comparison with Other Subjects: Through an Examination of the Explanation of the Curriculum Guidelines for “Secondary Home Economics Education” kn-title=学生による家庭科と他教科の比較を通した教科観の再考 ―「 中等家庭科教育法」における学習指導要領解説の検討を通して ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿では，中等家庭科教員養成課程に在籍する２年生の必修科目「中等家庭科教育法」において，家庭科と他教科を比較（共通点や相違点を整理）する機会を設けることで，受講した学生の家庭科に対する教科観がどのように変容するのかを調査することを目的とした。
　その結果，他教科の中学校学習指導要領解説の記載内容から，学生は家庭科と各教科との関連性を認識し，他者の生活に対する価値観や考え方について理解を深めること，個人の生活が社会に影響を与えることについて理解を深めることなど，家庭科の学習が担う役割を新たに認識することができたと推察された。また，授業後の家庭科に対する教科観は，比較対象とした他教科による影響が見られ，「多様な生き方」，「様々な価値観や生き方」，「社会での課題を発見し，改善する力」，「未来の社会をつくる」等の新たな記述が見られた。 en-copyright= kn-copyright= en-aut-name=TAKUMAChiharu en-aut-sei=TAKUMA en-aut-mei=Chiharu kn-aut-name=詫間千晴 kn-aut-sei=詫間 kn-aut-mei=千晴 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=家庭科教員養成課程 kn-keyword=家庭科教員養成課程 en-keyword=教科観 kn-keyword=教科観 en-keyword=家庭科 kn-keyword=家庭科 en-keyword=他教科 kn-keyword=他教科 en-keyword=比較 kn-keyword=比較 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=85 end-page=104 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Practice and Examination of Remaking Aprons Using Old Shirts in Elementary School Home Economics Classes: Development of the Home Economics Curriculum Based on the ESD (Ⅳ) kn-title=小学校家庭科における古ワイシャツを用いたリメイクエプロン製作の実践と検討 ― ESDを視点とした家庭科教育内容開発研究（Ⅳ）― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本継続研究の目的は，学校教育に社会的使命として求められているESDを視点とした小・中・高等学校家庭科の教育内容開発を行うことにある。本稿では，小学校家庭科において，従来，最も多くの学習時間が充てられてきた「被服製作学習」が「布を用いた製作」となり，製作時間短縮のために，市販のキットを用いた袋類やエプロン製作が実践されていることに着目し，古ワイシャツを用いたリメイクエプロンの製作を通して，児童に「自分と被服との関係」と「リメイクの意味」を考えさせる授業を開発し，この実践結果から小学校家庭科における「製作学習」の問い直しを行った。 en-copyright= kn-copyright= en-aut-name=SATOSono en-aut-sei=SATO en-aut-mei=Sono kn-aut-name=佐藤園 kn-aut-sei=佐藤 kn-aut-mei=園 aut-affil-num=1 ORCID= en-aut-name=HIRATAMichiko en-aut-sei=HIRATA en-aut-mei=Michiko kn-aut-name=平田美智子 kn-aut-sei=平田 kn-aut-mei=美智子 aut-affil-num=2 ORCID= en-aut-name=NOBUKIYOAkiko en-aut-sei=NOBUKIYO en-aut-mei=Akiko kn-aut-name=信清亜希子 kn-aut-sei=信清 kn-aut-mei=亜希子 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Kurashiki Washu High School kn-affil=岡山県立倉敷鷲羽高等学校 affil-num=3 en-affil=Kibichuo Town Toyono Elementary School kn-affil=岡山県吉備中央町立豊野小学校 en-keyword=家庭科 kn-keyword=家庭科 en-keyword=ESD kn-keyword=ESD en-keyword=内容開発研究 kn-keyword=内容開発研究 en-keyword=リメイクエプロン kn-keyword=リメイクエプロン en-keyword=小学校 kn-keyword=小学校 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=77 end-page=84 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Basic Research on the Appreciation of Sculpture Works by Children in Schools for the Blind -Through the Arrangement of Issues Based on the Literature Survey- kn-title=「創造性が社会と出会う美術教育」による教員の学びに関する基礎研究 ―「市井 no 姿勢 ni 学ぶプロジェクト」の課題整理 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本論文は，美術科の教員が新しい価値の生成を目指した授業研究やカリキュラム構築を行うための基礎研究にあたるものであり，その目的は，教員も新しい価値を求めて学び続ける力を培うために「市井no姿勢ni学ぶ」プロジェクト（以下，市井プロジェクトと表記）の有用性を確認することである。市井プロジェクトとは，①教員が日常生活で出会った他者と会い，②他者が学んできたことについてインタビューし，③②を生かした授業を実施し，④②で話を聞かせていただいた他者と③の授業検討を行うというものである。本論文では，①と②の成果と課題をまとめた。成果は，②インタビューを通して教員自身の学びが変容する姿を確認し，インタビュー相手であるK氏自身にも変容が見られたことである。その一方で，課題は，K氏とインタビューの質問者との関係性による検討が行えていない点である。 en-copyright= kn-copyright= en-aut-name=MATSUURAAi en-aut-sei=MATSUURA en-aut-mei=Ai kn-aut-name=松浦藍 kn-aut-sei=松浦 kn-aut-mei=藍 aut-affil-num=1 ORCID= en-aut-name=SENOYusuke en-aut-sei=SENO en-aut-mei=Yusuke kn-aut-name=妹尾佑介 kn-aut-sei=妹尾 kn-aut-mei=佑介 aut-affil-num=2 ORCID= en-aut-name=KIYOTATetsuo en-aut-sei=KIYOTA en-aut-mei=Tetsuo kn-aut-name=清田哲男 kn-aut-sei=清田 kn-aut-mei=哲男 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Okayama Prefectural Tamashima High School kn-affil=岡山県立玉島高等学校 affil-num=3 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=美術教育 kn-keyword=美術教育 en-keyword=創造性 kn-keyword=創造性 en-keyword=研修 kn-keyword=研修 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=67 end-page=76 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Music Education Practice Based on the Region: An Improvisation Workshop at a Public Elementary School in Tamano City, Okayama kn-title=地域を見つめ直す音楽教育実践の検討 ― 岡山県玉野市内の公立小学校における即興演奏ワークショップを例に ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究は，地域の文化や遺産，環境を念頭に置いた創造的な音楽教育によって，県内の人口減少に起因する課題の改善を図ることを目的としている。同時に，その創作教育を通じて，児童の柔軟な創造力や多様性を認める意識を育むこともねらっている。本研究において実践した取組は，現代音楽的表現を取り入れた即興演奏ワークショップである。
　本稿では2024 年に行った玉野市内の小学校におけるワークショップの内容を中心に論じる。本ワークショップは，児童が柔軟かつ多様な創作表現を実践する場となったが，児童と地域住民らがその地域の特色を認識する機会としては新たな課題を生んだ。地域と創造的音楽教育を結んだ研究は実例が少なく，模索の段階であるため，本ワークショップを省みた上で今後の改善に繋げたい。 en-copyright= kn-copyright= en-aut-name=OKAMOTOShinsuke en-aut-sei=OKAMOTO en-aut-mei=Shinsuke kn-aut-name=岡本伸介 kn-aut-sei=岡本 kn-aut-mei=伸介 aut-affil-num=1 ORCID= en-aut-name=MASUDAKenta en-aut-sei=MASUDA en-aut-mei=Kenta kn-aut-name=増田建太 kn-aut-sei=増田 kn-aut-mei=建太 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Faculty of Education, University of Toyama kn-affil=富山大学学術研究部教育学系 en-keyword=音楽教育 kn-keyword=音楽教育 en-keyword=地域教育 kn-keyword=地域教育 en-keyword=即興演奏 kn-keyword=即興演奏 en-keyword=作曲 kn-keyword=作曲 en-keyword=現代音楽 kn-keyword=現代音楽 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=57 end-page=65 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Research Trends in Children’s Music Education and Behavior kn-title=子供の音楽行動に関わる研究動向 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿では，音楽教育研究の現状と今後の課題に関する研究動向から，保育者の専門性として認識すべき観点を導くために，子どもの即興的な音楽行動を手掛かりに専門的示唆を得ることを目的とした。子供の音楽行動は，単に音楽的な活動だけでなく，子どもの感受性や創造性を育む重要な要素であり，保育者の専門性がこのプロセスで重要な役割を示す。創造性を育成する手がかりとして，保育者が音楽表現の中で子供との対話を深め，子供の自然な音楽的行動を引き出す方法を模索する重要性，音楽文化の継承とその多様性が議論されていることから，保育現場における音や音楽の枠組みの再検討を提起した。 en-copyright= kn-copyright= en-aut-name=TAKASUHiromi en-aut-sei=TAKASU en-aut-mei=Hiromi kn-aut-name=髙須裕美 kn-aut-sei=髙須 kn-aut-mei=裕美 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=保育者の専門性 kn-keyword=保育者の専門性 en-keyword=子どもの音楽文化 kn-keyword=子どもの音楽文化 en-keyword=即興性 kn-keyword=即興性 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=47 end-page=56 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Classical Japanese Instrument Music: Connecting Local Communities and the Global World (2) −Developing ‘Intercultural Competence’ in Next Generation Cultural Exchange − kn-title=地域社会とグローバルをつなぐ和楽器音楽次世代育成の実践研究（２）― 国際文化交流における「異文化間能力」育成の可能性 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究は，地域社会とグローバルをつなぐ和楽器音楽次世代育成の実践研究の一環として実施した「おかやま国際和楽器学生フェスティバル」について，「異文化間能力」育成の視点からその可能性について検討したものである。
　国内の学生については，①和楽器を介した繋がり／音楽的な協働，②演奏の質に関する違いの認識，③ 海外の和楽器演奏者に対する認識の３点が，海外の学生については，①表現スタイルや技術に関する違いの認識，②和楽器音楽の本質の理解，③演奏者としての学びと成長に対する意識の３点が，特徴として示された。「異文化間能力」の視点からは，国内外共に「文化的多様性」と「絶対的正統性の緩和」についての認識が認められ，柔軟で且つ寛容な和楽器との向き合い方が形成されていたことが明らかとなった。また「共感・協働のスキル」については，特に国内の学生に多く認められる結果となった。 en-copyright= kn-copyright= en-aut-name=HAYAKAWARinko en-aut-sei=HAYAKAWA en-aut-mei=Rinko kn-aut-name=早川倫子 kn-aut-sei=早川 kn-aut-mei=倫子 aut-affil-num=1 ORCID= en-aut-name=TAKASUHiromi en-aut-sei=TAKASU en-aut-mei=Hiromi kn-aut-name=髙須裕美 kn-aut-sei=髙須 kn-aut-mei=裕美 aut-affil-num=2 ORCID= en-aut-name=SHIMIZUNaoko en-aut-sei=SHIMIZU en-aut-mei=Naoko kn-aut-name=清水尚子 kn-aut-sei=清水 kn-aut-mei=尚子 aut-affil-num=3 ORCID= en-aut-name=YAMAJIMiho en-aut-sei=YAMAJI en-aut-mei=Miho kn-aut-name=山路みほ kn-aut-sei=山路 kn-aut-mei=みほ aut-affil-num=4 ORCID= en-aut-name=BEPPUYuko en-aut-sei=BEPPU en-aut-mei=Yuko kn-aut-name=別府祐子 kn-aut-sei=別府 kn-aut-mei=祐子 aut-affil-num=5 ORCID= en-aut-name=HIGUCHIAki en-aut-sei=HIGUCHI en-aut-mei=Aki kn-aut-name=樋口亜希 kn-aut-sei=樋口 kn-aut-mei=亜希 aut-affil-num=6 ORCID= en-aut-name=NAKAMURAAi en-aut-sei=NAKAMURA en-aut-mei=Ai kn-aut-name=中村愛 kn-aut-sei=中村 kn-aut-mei=愛 aut-affil-num=7 ORCID= en-aut-name=MIYOSHIKeiko en-aut-sei=MIYOSHI en-aut-mei=Keiko kn-aut-name=三好啓子 kn-aut-sei=三好 kn-aut-mei=啓子 aut-affil-num=8 ORCID= en-aut-name=TOSAChihiro en-aut-sei=TOSA en-aut-mei=Chihiro kn-aut-name=土佐千紘 kn-aut-sei=土佐 kn-aut-mei=千紘 aut-affil-num=9 ORCID= en-aut-name=HANAKUSAYoko en-aut-sei=HANAKUSA en-aut-mei=Yoko kn-aut-name=花草容子 kn-aut-sei=花草 kn-aut-mei=容子 aut-affil-num=10 ORCID= en-aut-name=TAKESHITANoriko en-aut-sei=TAKESHITA en-aut-mei=Noriko kn-aut-name=竹下則子 kn-aut-sei=竹下 kn-aut-mei=則子 aut-affil-num=11 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=3 en-affil=Doctoral Student at the Joint Graduate School in Science of School Education Hyogo University of Teacher Education (Okayama University) kn-affil=兵庫教育大学大学院連合学校教育学研究科博士課程（岡山大学所属） affil-num=4 en-affil=Koto Player kn-affil=箏曲演奏家 affil-num=5 en-affil=Department of Early Childhood Education and Care, Kurashiki City College kn-affil=倉敷短期大学保育学科 affil-num=6 en-affil=Okayama Prefectural School for the Deaf kn-affil=岡山県立岡山聾学校 affil-num=7 en-affil=Doctoral Student at the Joint Graduate School in Science of School Education Hyogo University of Teacher Education (Okayama University) kn-affil=兵庫教育大学大学院連合学校教育学研究科博士課程（岡山大学所属） affil-num=8 en-affil=Master’s Student at the Graduate School of Education in Okayama University kn-affil=岡山大学大学院教育学研究科修士課程 affil-num=9 en-affil=Master’s Student at the Graduate School of Education in Okayama University kn-affil=岡山大学大学院教育学研究科修士課程 affil-num=10 en-affil=Research Student at the Joint Graduate School in Science of School Education Hyogo University of Teacher Education (Okayama University) kn-affil=兵庫教育大学大学院連合学校教育学研究科研究生（岡山大学所属） affil-num=11 en-affil=Biwako-Gakuin University kn-affil=びわこ学院大学 en-keyword=和楽器音楽 kn-keyword=和楽器音楽 en-keyword=異文化間能力 kn-keyword=異文化間能力 en-keyword=グローバル kn-keyword=グローバル en-keyword=次世代育成 kn-keyword=次世代育成 en-keyword=質問紙調査 kn-keyword=質問紙調査 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=35 end-page=45 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=This Study on “Modeling Self-Transformation” and “Gestaltkreis” in the “Craftical Formation” of Individual Creators: Understanding Creative Processes Toward the Realization of “Individually Optimized Learning” kn-title=個々の制作者の「工芸的造形」における「造形的自己変革」と「ゲシュタルトクライス」の文献研究 ―「 個別最適な学び」の実現に向けた制作者の制作過程を捉える視点の検討 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究では，造形行為の過程で制作者が経験する学びを分析し考察する視点について，特に，工芸制作に関連した文献の調査により検討することを目的とした。そのため，制作者自身の見方，感じ方，考え方と造形物を共に形成していく工芸の制作過程としての金子賢治の「工芸的造形」と，制作者が自身の変化と素材の変化を一体とした造形行為を連鎖させていく学びの過程としての橋本真之の「造形的自己変革」と，人間の「自己」が生み出されていく過程としてのヴァイツゼッカーの「ゲシュタルトクライス」について文献調査した。これにより，制作者自身の見方，感じ方，考え方と造形物を共に形成していきながら，制作者自身の変化と素材の変化が一体となって生じる造形行為の過程において，自らの「自己」を生み出し続けていく制作者の学びを分析し考察する視点をまとめた。今後は，本研究の成果を検証するため，本研究で示した視点に立つ事例研究の実施を課題とする。 en-copyright= kn-copyright= en-aut-name=OHIRAShuya en-aut-sei=OHIRA en-aut-mei=Shuya kn-aut-name=大平修也 kn-aut-sei=大平 kn-aut-mei=修也 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=工芸的造形 kn-keyword=工芸的造形 en-keyword=造形的自己変革 kn-keyword=造形的自己変革 en-keyword=ゲシュタルトクライス kn-keyword=ゲシュタルトクライス en-keyword=令和の日本型学校教育 kn-keyword=令和の日本型学校教育 en-keyword=個別最適な学び kn-keyword=個別最適な学び END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=27 end-page=33 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Proposal of Developmental Stage-Specific Achievement Indicators for Self-Care and Peer Support in Food Allergy Management kn-title=食物アレルギーのセルフケアとピアサポートに関する発達段階別到達指標の提案 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　食物アレルギーのある子が健康で安全に過ごすためには，本人が必要なセルフケアを身につけることに加え，周囲の子が食物アレルギーについて理解し，適切に支援できる環境づくりが重要である。そのため，食物アレルギーに関する指導は，食物アレルギーのある子だけでなく，ない子に対しても発達段階に合わせて実施することが求められる。
　そこで本研究は，各発達段階で子供に必要なセルフケアとピアサポートのスキルを包括的かつ具体的に整理し，指導の一助となる「食物アレルギーのセルフケアとピアサポートに関する発達段階別到達指標」を提案する。指標の作成時には，教員が疾患の特徴や子供の実態を踏まえて指導するため，学校生活における具体的なスキルとなるように表現を工夫した。 en-copyright= kn-copyright= en-aut-name=SHINTAKUYumiko en-aut-sei=SHINTAKU en-aut-mei=Yumiko kn-aut-name=新宅由実子 kn-aut-sei=新宅 kn-aut-mei=由実子 aut-affil-num=1 ORCID= en-aut-name=KAMIMURAHiroko en-aut-sei=KAMIMURA en-aut-mei=Hiroko kn-aut-name=上村弘子 kn-aut-sei=上村 kn-aut-mei=弘子 aut-affil-num=2 ORCID= en-aut-name=TSUSHIMAAiko en-aut-sei=TSUSHIMA en-aut-mei=Aiko kn-aut-name=津島愛子 kn-aut-sei=津島 kn-aut-mei=愛子 aut-affil-num=3 ORCID= en-aut-name=TAKASEAtsushi en-aut-sei=TAKASE en-aut-mei=Atsushi kn-aut-name=髙瀬淳 kn-aut-sei=髙瀬 kn-aut-mei=淳 aut-affil-num=4 ORCID= affil-num=1 en-affil=Graduate School of Education, Hyogo University of Teacher Education kn-affil=兵庫教育大学大学院連合学校教育学研究科（博士課程） affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=3 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=4 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=食物アレルギー kn-keyword=食物アレルギー en-keyword=発達段階 kn-keyword=発達段階 en-keyword=セルフケア kn-keyword=セルフケア en-keyword=ピアサポート kn-keyword=ピアサポート en-keyword=慢性疾患 kn-keyword=慢性疾患 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=15 end-page=26 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Conceptual Arrangement of Resistance to Change in Organizations: Toward Integrative Understanding from the Perspective of Multidimensional Attitudes kn-title=組織における変化への抵抗の概念整理 ― 多次元的態度の視点からの統合的理解に向けて ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　VUCA時代と呼ばれる現代社会において，組織には急速に変化する社会環境への柔軟な対応力が求められている。しかし，新たな制度・施策を導入しても組織変革が進まないケースは多い。組織における変化への抵抗は古くから研究されてきた現象であり，変革へのレディネスやコミットメントなどさまざまな概念が提唱されてきた。他方で，これらの概念の内容の重複による混乱が危惧されており，VUCAが注目されはじめた2000 年代以降も，変化への抵抗に関連する新たな概念が提唱されている。こうした混乱を解決し，統合的な理解を図るため，本稿では既往知見をレビューし，社会心理学で伝統的な多次元的態度（認知，感情，行動）の視点から，変化への抵抗とその関連概念を整理した。 en-copyright= kn-copyright= en-aut-name=MISAWARyo en-aut-sei=MISAWA en-aut-mei=Ryo kn-aut-name=三沢良 kn-aut-sei=三沢 kn-aut-mei=良 aut-affil-num=1 ORCID= en-aut-name=ARIYOSHIMie en-aut-sei=ARIYOSHI en-aut-mei=Mie kn-aut-name=有吉美恵 kn-aut-sei=有吉 kn-aut-mei=美恵 aut-affil-num=2 ORCID= en-aut-name=HASEGAWANaoko en-aut-sei=HASEGAWA en-aut-mei=Naoko kn-aut-name=長谷川尚子 kn-aut-sei=長谷川 kn-aut-mei=尚子 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Deparment of Psychology, Kansai University of International Studies kn-affil=関西国際大学心理学部 affil-num=3 en-affil=Faculty of Human Sciences, Department of Psychology, Bunkyo University kn-affil=文教大学人間科学部心理学科 en-keyword=組織変革 kn-keyword=組織変革 en-keyword=変化への抵抗 kn-keyword=変化への抵抗 en-keyword=多次元的態度 kn-keyword=多次元的態度 en-keyword=文献レビュー kn-keyword=文献レビュー END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page=1 end-page=13 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Wie setzt sich die Didaktik mit der “Learnification of Education” auseinnander? – Ein Dialog mit Ewald Terhart – kn-title=教育方法学は「教育の学習化」にどう応答するか ― ドイツ教授学との対話 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿は，2024 年10 月13 日（日）に北海道大学で開かれた日本教育方法学会第60 回大会ラウンドテーブル：教育方法学は「教育の学習化」にどう応答するか―ドイツ教授学との対話―（Wie setzt sich die Didaktik mit der “Lernification of Education” auseinander? ― Ein Dialog mit Ewald Terhart ―）に招聘したエヴァルト・テアハルトの講演，久田敏彦による指定討論，フロアとの質疑応答をまとめるとともに，講演と議論を踏まえたドイツ教授学の今日的課題を検討することを目的とする。テアハルトの動向整理から，ビースタによって提起された教育の「学習化（Learnification）」にドイツ教授学がどのように対峙しているかを検討し，ビースタによる「教えることの復権」が一般教授学研究の福音たり得ないこと，他分野との協働の具体とその意義は未だ明確な位置づけを得られていないことを明らかにした。 en-copyright= kn-copyright= en-aut-name=MIYAMOTOYuichi en-aut-sei=MIYAMOTO en-aut-mei=Yuichi kn-aut-name=宮本勇一 kn-aut-sei=宮本 kn-aut-mei=勇一 aut-affil-num=1 ORCID= en-aut-name=TERHARTEwald en-aut-sei=TERHART en-aut-mei=Ewald kn-aut-name=テアハルトエヴァルト kn-aut-sei=テアハルト kn-aut-mei=エヴァルト aut-affil-num=2 ORCID= en-aut-name=HISADAToshihiko en-aut-sei=HISADA en-aut-mei=Toshihiko kn-aut-name=久田敏彦 kn-aut-sei=久田 kn-aut-mei=敏彦 aut-affil-num=3 ORCID= en-aut-name=MATSUDAMitsuru en-aut-sei=MATSUDA en-aut-mei=Mitsuru kn-aut-name=松田充 kn-aut-sei=松田 kn-aut-mei=充 aut-affil-num=4 ORCID= en-aut-name=KUMAIShota en-aut-sei=KUMAI en-aut-mei=Shota kn-aut-name=熊井将太 kn-aut-sei=熊井 kn-aut-mei=将太 aut-affil-num=5 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Universität Münster kn-affil=ミュンスター大学 affil-num=3 en-affil=Osaka Kyoiku University kn-affil=大阪教育大学 affil-num=4 en-affil=Hyogo University of Teacher Education kn-affil=兵庫教育大学 affil-num=5 en-affil=Yasuda Women’s Univeristy kn-affil=安田女子大学 en-keyword=ドイツ教授学 kn-keyword=ドイツ教授学 en-keyword=テアハルト kn-keyword=テアハルト en-keyword=教育の学習化 kn-keyword=教育の学習化 en-keyword=ビースタインパクト kn-keyword=ビースタインパクト en-keyword=教育方法学 kn-keyword=教育方法学 END start-ver=1.4 cd-journal=joma no-vol=188 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=表紙・目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=31 cd-vols= no-issue=3 article-no= start-page=102660 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202503 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Intention and potential determinants of COVID-19 vaccination among healthcare workers at a single university hospital in Japan, 2024–2025 pre-season en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: Financial accessibility has emerged as a significant barrier to vaccine uptake following the cessation of universal public funding for coronavirus disease 2019 (COVID-19) vaccination programs. This investigation assessed the intention and determinant factors of COVID-19 vaccination among healthcare workers in Japan in the 2024–2025 pre-season.
Methods: A retrospective survey was conducted utilizing data collected from hospital staff at Okayama University Hospital, Japan, to inform the COVID-19 vaccination strategy in October 2024. The analysis evaluated demographic characteristics, vaccine intention, perceived barriers to vaccination, and maximum acceptable out-of-pocket expenditure.
Results: The study population of 3417 respondents comprised 843 medical doctors (24.7 %), 1131 nurses (33.1 %), 320 other medical staff (9.4 %), 286 dental doctors (8.4 %), and 627 administrative officers (18.3 %). At full cost, 2109 (61.7 %) indicated no intention to receive vaccination, while only 4.4 % expressed willingness to be vaccinated and 33.9 % remained undecided. With total self-payment, the vaccination acceptance rates were the highest and lowest among medical doctors (11.4 %) and nurses (1.0 %), respectively. Cost (38.1 %), followed by safety issues (29.5 %) and concerns regarding efficacy or medical necessity (20.3 %), emerged as the primary barrier. The projected vaccination intention increased to 43.9 % and 54.9 % at reduced self-pay costs of 3000 JPY and 5000 JPY, respectively.
Conclusions: Addressing financial constraints through policy interventions could be effective strategies in increasing overall vaccination coverage among healthcare workers. In addition, providing tailored education on vaccine safety, efficacy, and necessity may further facilitate increased vaccine uptake within this critical population. en-copyright= kn-copyright= en-aut-name=HagiyaHideharu en-aut-sei=Hagiya en-aut-mei=Hideharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FujitaYasushi en-aut-sei=Fujita en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KiguchiTakashi en-aut-sei=Kiguchi en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ManabeYohei en-aut-sei=Manabe en-aut-mei=Yohei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Infectious Diseases, Okayama University Hospital kn-affil= affil-num=2 en-affil=Division of Infection Prevention and Control, Okayama University Hospital kn-affil= affil-num=3 en-affil=Division of Infection Prevention and Control, Okayama University Hospital kn-affil= affil-num=4 en-affil=Division of Infection Prevention and Control, Okayama University Hospital kn-affil= en-keyword=COVID-19 kn-keyword=COVID-19 en-keyword=Immunization kn-keyword=Immunization en-keyword=Reimbursement kn-keyword=Reimbursement en-keyword=Healthcare workers kn-keyword=Healthcare workers en-keyword=Financial support kn-keyword=Financial support END start-ver=1.4 cd-journal=joma no-vol=209 cd-vols= no-issue= article-no= start-page=114663 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202504 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Repeated sequential administration of pegylated emulsion of SU5416 and liposomal paclitaxel enhances anti-tumor effect in 4T1 breast cancer-bearing mice en-subtitle= kn-subtitle= en-abstract= kn-abstract=To improve vascular normalization strategy for intractable triple-negative breast cancer 4T1, we examined the anti-tumor effects of repeated sequential administration of polyethylene glycol (PEG)-modified emulsion of SU5416 (PE-SU5416), a vascular endothelial growth factor (VEGF) receptor-2 kinase inhibitor, and PEG-modified liposomal paclitaxel (PL-PTX) in mice bearing 4T1 cells. Three sequential administrations (Seq×3) of PE-SU5416 and PL-PTX exhibited significantly higher anti-tumor activity than a single sequential administration (Seq×1). The tumor vasculatures were structurally normalized until after two PE-SU5416 (PE-SU5416×2) or sequential (Seq×2) administrations, while the improvement in vascular function, such as oxygen supply, blood flow, and PEG-liposomal distribution, was evident until after three administrations of PE-SU5416 (PE-SU5416×3) and Seq×3. Although some discrepancies between the structural and functional improvement in tumor vasculatures were observed after PE-SU5416×3 and Seq×3, cancer-associated fibroblasts (CAFs) and collagen levels were significantly reduced after PE-SU5416×2, PE-SU5416×3, Seq×2, and Seq×3, suggesting that a possible decrease in interstitial fluid pressure due to the reduction in CAFs and collagen would have compensated for vascular function. Furthermore, PE-SU5416×2, PE-SU5416×3, Seq×2, and Seq×3 significantly decreased tumor growth factor-β (TGF-β), an activator of CAFs, in tumor tissues, suggesting that the reduction in TGF-β levels by PE-SU5416 suppresses CAF activation. en-copyright= kn-copyright= en-aut-name=MaruyamaMasato en-aut-sei=Maruyama en-aut-mei=Masato kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ToriiReiya en-aut-sei=Torii en-aut-mei=Reiya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MatsuiHazuki en-aut-sei=Matsui en-aut-mei=Hazuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HayashiHiroki en-aut-sei=Hayashi en-aut-mei=Hiroki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OgawaraKen-ichi en-aut-sei=Ogawara en-aut-mei=Ken-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HigakiKazutaka en-aut-sei=Higaki en-aut-mei=Kazutaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Laboratory of Pharmaceutics, Kobe Pharmaceutical University kn-affil= affil-num=6 en-affil=Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Drug delivery kn-keyword=Drug delivery en-keyword=Vascular normalization kn-keyword=Vascular normalization en-keyword=Breast cancer kn-keyword=Breast cancer en-keyword=Liposome kn-keyword=Liposome en-keyword=Cancer-associated fibroblast kn-keyword=Cancer-associated fibroblast END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=1 article-no= start-page=2 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Enhancing Campus Environment: Real-Time Air Quality Monitoring Through IoT and Web Technologies en-subtitle= kn-subtitle= en-abstract= kn-abstract=Nowadays, enhancing campus environments through mitigations of air pollutions is an essential endeavor to support academic achievements, health, and safety of students and staffs in higher educational institutes. In laboratories, pollutants from welding, auto repairs, or chemical experiments can drastically degrade the air quality in the campus, endangering the respiratory and cognitive health of students and staffs. Besides, in universities in Indonesia, automobile emissions of harmful substances such as carbon monoxide (CO), nitrogen dioxide (NO2), and hydrocarbon (HC) have been a serious problem for a long time. Almost everybody is using a motorbike or a car every day in daily life, while the number of students is continuously increasing. However, people in many campuses including managements do not be aware these problems, since air quality is not monitored. In this paper, we present a real-time air quality monitoring system utilizing Internet of Things (IoT) integrated sensors capable of detecting pollutants and measuring environmental conditions to visualize them. By transmitting data to the SEMAR IoT application server platform via an ESP32 microcontroller, this system provides instant alerts through a web application and Telegram notifications when pollutant levels exceed safe thresholds. For evaluations of the proposed system, we adopted three sensors to measure the levels of CO, NO2, and HC and conducted experiments in three sites, namely, Mechatronics Laboratory, Power and Emission Laboratory, and Parking Lot, at the State Polytechnic of Malang, Indonesia. Then, the results reveal Good, Unhealthy, and Dangerous for them, respectively, among the five categories defined by the Indonesian government. The system highlighted its ability to monitor air quality fluctuations, trigger warnings of hazardous conditions, and inform the campus community. The correlation of the sensor levels can identify the relationship of each pollutant, which provides insight into the characteristics of pollutants in a particular scenario. en-copyright= kn-copyright= en-aut-name=RahmadaniAlfiandi Aulia en-aut-sei=Rahmadani en-aut-mei=Alfiandi Aulia kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SyaifudinYan Watequlis en-aut-sei=Syaifudin en-aut-mei=Yan Watequlis kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SetiawanBudhy en-aut-sei=Setiawan en-aut-mei=Budhy kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=PandumanYohanes Yohanie Fridelin en-aut-sei=Panduman en-aut-mei=Yohanes Yohanie Fridelin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of Electrical Engineering, State Polytechnic of Malang kn-affil= affil-num=2 en-affil=Department of Information Technology, State Polytechnic of Malang kn-affil= affil-num=3 en-affil=Department of Electrical Engineering, State Polytechnic of Malang kn-affil= affil-num=4 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=5 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= en-keyword=Internet of Things kn-keyword=Internet of Things en-keyword= campus air quality kn-keyword= campus air quality en-keyword= pollutant detection kn-keyword= pollutant detection en-keyword= SEMAR kn-keyword= SEMAR en-keyword= sensor technology kn-keyword= sensor technology en-keyword= web application kn-keyword= web application END start-ver=1.4 cd-journal=joma no-vol=197 cd-vols= no-issue= article-no= start-page=115301 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202503 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Fraglide-1 from traditional Chinese aromatic vinegar: A natural AhR antagonist for atopic dermatitis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Traditional Chinese Zhenjiang aromatic vinegar (Kozu) contains Fraglide-1 (FG1), a bioactive lactone with demonstrated peroxisome proliferator-activated receptor gamma (PPARγ) agonist and antioxidant activities. This study explored FG1's novel ability to antagonize the aryl hydrocarbon receptor (AhR) signaling pathway, which regulates artemin expression and contributes to itching and inflammation in atopic dermatitis. Through molecular docking simulations and cell-based assays in human keratinocytes, we demonstrated FG1's potent antagonistic activity against AhR signaling. FG1 effectively suppressed FICZ-induced inflammatory responses, including artemin expression, with potency (half maximal inhibitory concentration, IC50 = 5.1 μM) comparable to the synthetic antagonist StemRegenin 1 (SR1) while demonstrating a superior safety profile (median lethal concentration, LC50 > 100 μM vs. 27.5 μM for SR1). These findings expand our understanding of bioactive compounds from traditional fermented foods and their regulatory effects on AhR signaling, providing a foundation for future studies on FG1's role in modulating skin inflammation. en-copyright= kn-copyright= en-aut-name=KatoKosuke en-aut-sei=Kato en-aut-mei=Kosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AkamatsuMiki en-aut-sei=Akamatsu en-aut-mei=Miki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KakimaruSaya en-aut-sei=Kakimaru en-aut-mei=Saya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KoreishiMayuko en-aut-sei=Koreishi en-aut-mei=Mayuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TakagiMasahiro en-aut-sei=Takagi en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MiyashitaMasahiro en-aut-sei=Miyashita en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MurataYoshiyuki en-aut-sei=Murata en-aut-mei=Yoshiyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NakamuraYoshimasa en-aut-sei=Nakamura en-aut-mei=Yoshimasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=SatohAyano en-aut-sei=Satoh en-aut-mei=Ayano kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=TsujinoYoshio en-aut-sei=Tsujino en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=5 en-affil=School of Materials Science, Japan Advanced Institute of Science and Technology kn-affil= affil-num=6 en-affil=Graduate School of Agriculture, Kyoto University kn-affil= affil-num=7 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=8 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=9 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=10 en-affil=Graduate School of Science, Technology and Innovation, Kobe University kn-affil= en-keyword=AhR kn-keyword=AhR en-keyword=Xenobiotic responsive element kn-keyword=Xenobiotic responsive element en-keyword=StemRegenin 1 kn-keyword=StemRegenin 1 en-keyword=ARNT kn-keyword=ARNT en-keyword=Atopic dermatitis kn-keyword=Atopic dermatitis en-keyword=Artemin kn-keyword=Artemin END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250212 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Spatiotemporal expression pattern of dyslexia susceptibility 1 candidate 1 (DYX1C1) during rat cerebral cortex development en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background Developmental dyslexia (DD) is a common learning disorder with significant consequences for affected individuals. Although several candidate genes, including dyslexia susceptibility 1 candidate 1 (DYX1C1), have been implicated in dyslexia, their role in brain development remains unclear. We aimed to elucidate the spatiotemporal expression patterns of DYX1C1 during cerebral cortex development in rats.
Methods We investigated DYX1C1 expression during cerebral cortex development using rat embryos at various gestational stages (E13.5, 15.5, 17.5 and 20.5) by immunohistochemistry (n = 7 embryos/stage), quantitative real-time PCR (n = 6), and in situ hybridization (n = 11–15).
Results The DYX1C1-positive cells were predominantly located in the outermost layers of the cortical plate, particularly at E15.5. DYX1C1 mRNA expression peaked at E15.5 and subsequently declined. DYX1C1-positive cells did not co-localize with reelin-positive Cajal-Retzius cells, but co-localized with neuronal markers expressed during development, and had shorter primary cilia than DYX1C1-negative cells.
Conclusions Our findings highlight the dynamic expression of DYX1C1 in the developing cerebral cortex of rats, implicating its involvement in neurodevelopmental processes. Further investigation of the functional interactions of DYX1C1, particularly its relationship with reelin and its role in cerebrocortical and hippocampal development, may provide insights into the pathophysiology of dyslexia and neurodevelopmental disorders. en-copyright= kn-copyright= en-aut-name=ZenshoKazumasa en-aut-sei=Zensho en-aut-mei=Kazumasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MiyazakiIkuko en-aut-sei=Miyazaki en-aut-mei=Ikuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IsseAika en-aut-sei=Isse en-aut-mei=Aika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MisawaIchika en-aut-sei=Misawa en-aut-mei=Ichika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MasaiKaori en-aut-sei=Masai en-aut-mei=Kaori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OkaMakio en-aut-sei=Oka en-aut-mei=Makio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=TsukaharaHirokazu en-aut-sei=Tsukahara en-aut-mei=Hirokazu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=AsanumaMasato en-aut-sei=Asanuma en-aut-mei=Masato kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Psychosocial Medicine, National Center for Child Health and Development kn-affil= affil-num=7 en-affil=Department of Pediatrics, Okayama University Hospital kn-affil= affil-num=8 en-affil=Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= END start-ver=1.4 cd-journal=joma no-vol=99 cd-vols= no-issue=3 article-no= start-page=e02166-24 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250213 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A capsidless (+)RNA yadokarivirus hosted by a dsRNA virus is infectious as particles, cDNA, and dsRNA en-subtitle= kn-subtitle= en-abstract= kn-abstract=Capsidless yadokariviruses (members of the order Yadokarivirales) with (+)RNA genomes divert the capsid of their partner icosahedral double-stranded RNA (dsRNA) viruses in different families of the order Ghabrivirales into the replication site. A yadokarivirus, AfSV2, has been reported from a German strain of the ascomycete fungus Aspergillus foetidus coinfected by two dsRNA viruses, a victorivirus (AfSV1, family Pseudototiviridae) and an alternavirus (AfFV, family Alternaviridae). Here, we identified AfSV1 as the partner of AfSV2 in a Japanese A. foetidus strain after showing the infectiousness of AfSV2 in three forms: virus particles (heterocapsid), transforming full-length complementary DNA (cDNA), and purified replicated form (RF) dsRNA that is believed to be inactive as a translational template. Virion transfection of virus-free A. foetidus protoplasts resulted in the generation of two strains infected either by AfSV1 alone or by both AfSV1 and AfSV2. Transformants with AfSV2 full-length cDNA launched AfSV2 infection only in the presence of AfSV1, but not those with AfSV2 RNA-directed RNA polymerase mutant cDNA. The purified fractions containing AfSV2 RF dsRNA also launched infection when transfected into protoplasts infected by AfSV1. Treatment with dsRNA-specific RNase III, but not with proteinase K, S1 nuclease, or DNase I, abolished the infectivity of AfSV2 RF dsRNA. Furthermore, we confirmed the infectiousness of gel-purified AfSV2 RF dsRNA in the presence of AfSV1. Taken together, our results show the unique infectious entity of AfSV2 and the expansion of yadokarivirus partners in the family Pseudototiviridae and provide interesting evolutionary insights. en-copyright= kn-copyright= en-aut-name=FadliMuhammad en-aut-sei=Fadli en-aut-mei=Muhammad kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HisanoSakae en-aut-sei=Hisano en-aut-mei=Sakae kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NovoaGuy en-aut-sei=Novoa en-aut-mei=Guy kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=CastónJosé R. en-aut-sei=Castón en-aut-mei=José R. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KondoHideki en-aut-sei=Kondo en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SuzukiNobuhiro en-aut-sei=Suzuki en-aut-mei=Nobuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Agrivirology Laboratory, Institute of Plant Science and Resources, Okayama University kn-affil= affil-num=2 en-affil=Agrivirology Laboratory, Institute of Plant Science and Resources, Okayama University kn-affil= affil-num=3 en-affil=Department of Structure of Macromolecules, Centro Nacional Biotecnología (CNB-CSIC), Campus de Cantoblanco kn-affil= affil-num=4 en-affil=Department of Structure of Macromolecules, Centro Nacional Biotecnología (CNB-CSIC), Campus de Cantoblanco kn-affil= affil-num=5 en-affil=Agrivirology Laboratory, Institute of Plant Science and Resources, Okayama University kn-affil= affil-num=6 en-affil=Agrivirology Laboratory, Institute of Plant Science and Resources, Okayama University kn-affil= en-keyword=yadokarivirus kn-keyword=yadokarivirus en-keyword=hetero-encapsidation kn-keyword=hetero-encapsidation en-keyword=partner dsRNA virus kn-keyword=partner dsRNA virus en-keyword=fungal virus kn-keyword=fungal virus en-keyword=Aspergillus foetidus kn-keyword=Aspergillus foetidus en-keyword=neo-lifestyle kn-keyword=neo-lifestyle END start-ver=1.4 cd-journal=joma no-vol=60 cd-vols= no-issue=1 article-no= start-page=vvae044 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202501 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The effects of soybeans and its derivatives on oral diseases: a narrative review en-subtitle= kn-subtitle= en-abstract= kn-abstract=Soybean is a widely utilized protein source that originated in China and has been associated with preventing and treating various diseases. Soy protein has been found to inhibit fat accumulation effectively, and soybeans contain isoflavones, saponins, phytic acid, and other substances with preventive and therapeutic effects on heart disease, cancer, and diabetes. Furthermore, processed soybean products, such as Avocado-Soybean unsaponifiable, Tempeh, and Bowman-Birk inhibitor, have demonstrated health benefits. These products have been shown to have antibacterial, antioxidant, and anticancer effects in oral diseases. Numerous experiments have provided evidence of the antibacterial, antioxidant, and anticancer effects of polyunsaturated fatty acids, isoflavones, and soybean polypeptides. This comprehensive review assesses the relationship and mechanism of soybeans and their derivatives on oral diseases, providing valuable insights into their prevention and treatment. en-copyright= kn-copyright= en-aut-name=CanyanKuang en-aut-sei=Canyan en-aut-mei=Kuang kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AriasZulema Rosalia en-aut-sei=Arias en-aut-mei=Zulema Rosalia kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OmoriKazuhiro en-aut-sei=Omori en-aut-mei=Kazuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamamotoTadashi en-aut-sei=Yamamoto en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=Shinoda-ItoYuki en-aut-sei=Shinoda-Ito en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TakashibaShogo en-aut-sei=Takashiba en-aut-mei=Shogo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Pathophysiology—Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Pathophysiology—Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Pathophysiology—Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=The Center for Graduate Medical Education (Dental Division), Okayama University Hospital kn-affil= affil-num=5 en-affil=Department of Pathophysiology—Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Pathophysiology—Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=soybean kn-keyword=soybean en-keyword=soy products kn-keyword=soy products en-keyword=oral diseases kn-keyword=oral diseases en-keyword=dental application kn-keyword=dental application en-keyword=antibacterial effect kn-keyword=antibacterial effect en-keyword=antioxidant kn-keyword=antioxidant en-keyword=anticancer kn-keyword=anticancer END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue= article-no= start-page=103026 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202506 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The antimalarial activity of transdermal N-89 mediated by inhibiting ERC gene expression in P. Berghei-infected mice en-subtitle= kn-subtitle= en-abstract= kn-abstract=Through studies of new antimalarial drugs, we identified 1,2,6,7-tetraoxaspiro[7.11]nonadecane (N-89) as a potential drug candidate. Here, we analyzed the antimalarial action of a transdermal formulation (td) of N-89, designed for easy use by children, using Plasmodium berghei-infected mice as a model for malaria patients. The td N-89 or artemisinin (ART) formulation was transdermally administered to P. berghei-infected mice with 0.2–0.4 % parasitemia, twice daily for four days, at an effective dose of 90 % for malaria. Parasitemia was decreased in td N-89 and td ART groups during the drug treatment; then, three of the eight mice in td N-89 group were completely cured without relapse. Additionally, abnormal trophozoites in td N-89 group were observed 8 h after administration and increased up to 24 h. To study the change in endoplasmic reticulum-resident calcium-binding protein (ERC) gene expression with td N-89, we investigated the gene expression of P. berghei ERC (PbERC) after td N-89 treatment. PbERC gene expression was increased time-dependently in control group, and was statistically decreased at 4 and 8 h and then increased similar to that of control group at 12 h in td ART group. In contrast, the expression in td N-89 group was almost steady starting from 0 h. We also studied parasite egress-related genes expression after td N-89 treatment, plasmepsin X, subtilisin-like protease 1 and merozoite surface protein 1, were suppressed at 12 h compared to control group. These results suggest that N-89 affects function of endoplasmic reticulum via regulating gene suppression and subsequently parasite growth is inhibited. en-copyright= kn-copyright= en-aut-name=MatsumoriHiroaki en-aut-sei=Matsumori en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=DinhThi Quyen en-aut-sei=Dinh en-aut-mei=Thi Quyen kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MiyoshiShin-ichi en-aut-sei=Miyoshi en-aut-mei=Shin-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MoritaMasayuki en-aut-sei=Morita en-aut-mei=Masayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KimHye-Sook en-aut-sei=Kim en-aut-mei=Hye-Sook kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Division of International Infectious Diseases Control, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Division of International Infectious Diseases Control, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Research Center for Intestinal Health Science, Okayama University kn-affil= affil-num=4 en-affil=Department of Anatomy, Kawasaki Medical School kn-affil= affil-num=5 en-affil=Division of International Infectious Diseases Control, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Synthetic antimalarial endoperoxide kn-keyword=Synthetic antimalarial endoperoxide en-keyword=Transdermal N-89 kn-keyword=Transdermal N-89 en-keyword=Artemisinin kn-keyword=Artemisinin en-keyword=In vivo kn-keyword=In vivo en-keyword=Abnormal trophozoite kn-keyword=Abnormal trophozoite en-keyword=Endoplasmic reticulum-resident calcium-binding protein (ERC) kn-keyword=Endoplasmic reticulum-resident calcium-binding protein (ERC) en-keyword=Parasite egress-related gene kn-keyword=Parasite egress-related gene END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=1 article-no= start-page=199 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Establishment of a rapid and quantitative method for detecting the range of infection exposure in preclinical dental education en-subtitle= kn-subtitle= en-abstract= kn-abstract=Backgrounds Safe dental treatments that prevent nosocomial and cross-infections are essential for patients and dental workers. However, dental students sometimes pay inadequate attention to infection control, especially in preclinical practice, because of too much focus on technical training, such as the use of equipment, etc. The spread of infections such as SARS-CoV-2, antibiotic-resistant bacteria, and oral bacteria are sometimes lethal for medically compromised patients. Thus, the rapid and inexpensive detection system to detect and measure dental practice-related infection spread during preclinical treatment is highly desired for dental education. This study aimed to establish a method to quantify and visualize infected areas using dental phantoms for safe and effective preclinical dental practices.
Methods At first, we developed artificial saliva as an in vitro study, including food-derived bacteria and fluorescence dye, which is safe for application to preclinical practice education. In vitro study, the correlation between adenosine triphosphate (ATP) levels and Lactobacillus colony numbers in yogurt was examined using the ATP fluorescent method, with colony counting on yogurt only and a mixture of yogurt and ultraviolet (UV)-sensitive hand lotion. The mixed liquid of yogurt and hand lotion was used as artificial saliva. Second, we used this artificial saliva in preclinical education. The degree of contamination of personal protective equipment and dental chairs in preclinical practice using this artificial saliva was determined using the ATP fluorescent method and measuring the luminescence areas among 10 dentists, 10 dental residents, and 10 fifth-grade dental students.
Results ATP levels and Lactobacillus colony numbers in yogurt were positively correlated with yogurt alone and a mixture of yogurt and UV-sensitive hand lotions (correlation coefficient & efDot; 1). Preclinical education using a mixture of artificial saliva successfully quantified and visualized infectious areas and droplets, which revealed significant differences in ATP amounts in personal protective equipment among groups according to years of experience as dental practitioners (p < 0.05).
Conclusions An education system for infection control constructed using artificial saliva containing Lactobacillus and a UV-sensitive fluorescent hand lotion quantified the infectious areas and degrees. Thus, this method is effective in preclinical practice using dental phantoms. en-copyright= kn-copyright= en-aut-name=UedaAyaka en-aut-sei=Ueda en-aut-mei=Ayaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=Shinoda-ItoYuki en-aut-sei=Shinoda-Ito en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=Takeuchi-HatanakaKazu en-aut-sei=Takeuchi-Hatanaka en-aut-mei=Kazu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ItoTakashi en-aut-sei=Ito en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OnoShintaro en-aut-sei=Ono en-aut-mei=Shintaro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HiraiKimito en-aut-sei=Hirai en-aut-mei=Kimito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=OmoriKazuhiro en-aut-sei=Omori en-aut-mei=Kazuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=YamamotoTadashi en-aut-sei=Yamamoto en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=TakashibaShogo en-aut-sei=Takashiba en-aut-mei=Shogo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil=Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Periodontics and Endodontics, Division of Dentistry, Okayama University Hospital kn-affil= affil-num=4 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital kn-affil= affil-num=5 en-affil=Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=6 en-affil=Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=7 en-affil=Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=8 en-affil=The Center for Graduate Medical Education (Dental Division), Okayama University Hospital kn-affil= affil-num=9 en-affil=Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Dental education kn-keyword=Dental education en-keyword=Infection control kn-keyword=Infection control en-keyword=Fluorescent dye kn-keyword=Fluorescent dye en-keyword=Adenosine triphosphate kn-keyword=Adenosine triphosphate en-keyword=Lactobacillus kn-keyword=Lactobacillus END start-ver=1.4 cd-journal=joma no-vol=2025 cd-vols= no-issue=1 article-no= start-page=013C01 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241226 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Modification on Thermal Motion in Geant4 for Neutron Capture Simulation in Gadolinium Loaded Water en-subtitle= kn-subtitle= en-abstract= kn-abstract=Neutron tagging is a fundamental technique for electron anti-neutrino detection via the inverse beta decay channel. A reported discrepancy in neutron detection efficiency between observational data and simulation predictions prompted an investigation into neutron capture modeling in Geant4. The study revealed that an overestimation of the thermal motion of hydrogen atoms in Geant4 impacts the fraction of captured nuclei. By manually modifying the Geant4 implementation, the simulation results align with calculations based on evaluated nuclear data and show good agreement with observables derived from the SK-Gd data. en-copyright= kn-copyright= en-aut-name=HinoY. en-aut-sei=Hino en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AbeK. en-aut-sei=Abe en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AsakaR. en-aut-sei=Asaka en-aut-mei=R. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HanS. en-aut-sei=Han en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HaradaM. en-aut-sei=Harada en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=IshitsukaM. en-aut-sei=Ishitsuka en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ItoH. en-aut-sei=Ito en-aut-mei=H. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=IzumiyamaS. en-aut-sei=Izumiyama en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KanemuraY. en-aut-sei=Kanemura en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=KoshioY. en-aut-sei=Koshio en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=NakanishiF. en-aut-sei=Nakanishi en-aut-mei=F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=SekiyaH. en-aut-sei=Sekiya en-aut-mei=H. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=YanoT. en-aut-sei=Yano en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= affil-num=1 en-affil=Department of Physics, Okayama University kn-affil= affil-num=2 en-affil=Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo kn-affil= affil-num=3 en-affil=Department of Physics, Faculty of Science and Technology, Tokyo University of Science kn-affil= affil-num=4 en-affil=Research Center for Cosmic Neutrinos, Institute for Cosmic Ray Research, University of Tokyo kn-affil= affil-num=5 en-affil=Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo kn-affil= affil-num=6 en-affil=Department of Physics, Faculty of Science and Technology, Tokyo University of Science kn-affil= affil-num=7 en-affil=Department of Physics, Faculty of Science and Technology, Tokyo University of Science kn-affil= affil-num=8 en-affil=Department of Physics, Tokyo Institute of Technology kn-affil= affil-num=9 en-affil=Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo kn-affil= affil-num=10 en-affil=Department of Physics, Okayama University kn-affil= affil-num=11 en-affil=Department of Physics, Okayama University kn-affil= affil-num=12 en-affil=Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo kn-affil= affil-num=13 en-affil=Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo kn-affil= END start-ver=1.4 cd-journal=joma no-vol=172 cd-vols= no-issue=2 article-no= start-page=471 end-page=479 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250122 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Identification of factors related to functional prognoses in craniopharyngiomas en-subtitle= kn-subtitle= en-abstract= kn-abstract=Purpose Craniopharyngiomas are histologically benign tumors, but their proximity to vital neurovascular structures can significantly deteriorate functional prognoses and severely restrict patients’ social interaction and activity. We retrospectively identified risk factors related to the functional prognoses in patients with craniopharyngioma treated at our center.
Methods A retrospective analysis was conducted on 40 patients who underwent surgery for craniopharyngioma and follow-up at our institution between 2003 and 2022. Functional prognoses were evaluated in terms of obesity (body mass index [BMI] ≥ 25 for adults, BMI-Z ≥ 1.65 for children), visual function, endocrine function, and social participation. We investigated whether patient characteristics, tumor size, tumor location, hypothalamic involvement, surgical hypothalamic damage, extent of resection, and recurrence rate correlated with these functional prognostic factors.
Results The median age at diagnosis was 28.0 years, with a median follow-up of 80.5 months. Postoperative obesity was present in 22 patients, and those with postoperative obesity had a significantly higher preoperative BMI or BMI-Z (preoperative BMI for adults: p = 0.074; preoperative BMI-Z for children: p = 0.020) and were significantly correlated with preoperative hypothalamic involvement grade 2 (p = 0.012) and surgical hypothalamic damage grade II (p = 0.0001). Deterioration in social participation was significantly associated with a larger tumor size (p = 0.023) and tumor recurrence (p = 0.0047).
Conclusions Patients with higher preoperative BMI or BMI-Z and hypothalamic involvement have a greater risk of postoperative obesity, and larger tumor size and recurrence can significantly deteriorate the rate of patients’ social participation. en-copyright= kn-copyright= en-aut-name=UmedaTsuyoshi en-aut-sei=Umeda en-aut-mei=Tsuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OtaniYoshihiro en-aut-sei=Otani en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FujiiKentaro en-aut-sei=Fujii en-aut-mei=Kentaro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=IshidaJoji en-aut-sei=Ishida en-aut-mei=Joji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HiranoShuichiro en-aut-sei=Hirano en-aut-mei=Shuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SurugaYasuki en-aut-sei=Suruga en-aut-mei=Yasuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KemmotsuNaoya en-aut-sei=Kemmotsu en-aut-mei=Naoya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=ImotoRyoji en-aut-sei=Imoto en-aut-mei=Ryoji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KegoyaYasuhito en-aut-sei=Kegoya en-aut-mei=Yasuhito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=MizutaRyo en-aut-sei=Mizuta en-aut-mei=Ryo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=InoueYohei en-aut-sei=Inoue en-aut-mei=Yohei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=HokamaMadoka en-aut-sei=Hokama en-aut-mei=Madoka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=MakiharaSeiichiro en-aut-sei=Makihara en-aut-mei=Seiichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=HasegawaKosei en-aut-sei=Hasegawa en-aut-mei=Kosei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=InagakiKenichi en-aut-sei=Inagaki en-aut-mei=Kenichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= en-aut-name=YasuharaTakao en-aut-sei=Yasuhara en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=17 ORCID= en-aut-name=TanakaShota en-aut-sei=Tanaka en-aut-mei=Shota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=18 ORCID= affil-num=1 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil= kn-affil= affil-num=10 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=11 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=12 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=13 en-affil=Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=14 en-affil=Department of Pediatrics, Okayama University Hospital kn-affil= affil-num=15 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=16 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=17 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=18 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=Craniopharyngioma kn-keyword=Craniopharyngioma en-keyword=Functional prognosis kn-keyword=Functional prognosis en-keyword=Obesity kn-keyword=Obesity en-keyword=Tumor size kn-keyword=Tumor size en-keyword=Social participation kn-keyword=Social participation en-keyword=Hypothalamic involvement kn-keyword=Hypothalamic involvement END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue=1 article-no= start-page=65 end-page=69 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202501 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Effectiveness of sensing gloves–applied virtual reality education system on hand hygiene practice: A randomized controlled trial en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: We developed a virtual reality (VR) education system and evaluated its clinical utility for promoting hand hygiene practices.
Methods: This prospective, 2-week, randomized controlled study conducted at Okayama University Hospital, Japan, from November 2023 to January 2024, involved 22 participants (18 medical students and 4 residents). A fully immersive 360° VR system (VIVE Pro Eye) using a head-mounted display and sensing gloves was used to develop 3 health care tasks in a virtual patient room—Environmental Cleaning, Gauze Exchange, and Urine Collection. After monitoring all participants' baseline usage data of portable hand-rubbing alcohol in the first week, we randomly assigned them into 1:1 groups (VR training and video lecture groups). The primary outcome was differences in hand-rubbed alcohol use before and after intervention.
Results: Before the intervention, alcohol use did not significantly differ between both groups. After the intervention, a significant increase in alcohol use was observed in the VR training group (median: 8.2 g vs 16.2 g; P = .019) but not in the video lecture group.
Conclusions: Our immersive 360° VR education system enhanced hand hygiene practices. Infection prevention and control practitioners and digital technology experts must collaborate to advance the development of superior educational devices and content. en-copyright= kn-copyright= en-aut-name=IzumiMahiro en-aut-sei=Izumi en-aut-mei=Mahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HagiyaHideharu en-aut-sei=Hagiya en-aut-mei=Hideharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OtsukaYuki en-aut-sei=Otsuka en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SoejimaYoshiaki en-aut-sei=Soejima en-aut-mei=Yoshiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=FukushimaShinnosuke en-aut-sei=Fukushima en-aut-mei=Shinnosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ShibataMitsunobu en-aut-sei=Shibata en-aut-mei=Mitsunobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=HirotaSatoshi en-aut-sei=Hirota en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KoyamaToshihiro en-aut-sei=Koyama en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=GofukuAkio en-aut-sei=Gofuku en-aut-mei=Akio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Quality Assurance Center, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=2 en-affil=Department of Infectious Diseases, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Infectious Diseases, Okayama University Hospital kn-affil= affil-num=6 en-affil=Quality Assurance Center, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=7 en-affil=Quality Assurance Center, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=8 en-affil=Department of Health Data Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=10 en-affil=Quality Assurance Center, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= en-keyword=Infection prevention and control kn-keyword=Infection prevention and control en-keyword=Medical-engineering collaboration kn-keyword=Medical-engineering collaboration END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241224 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The perception of plastic waste and composition of boathouse waste in floating villages on Tonlé Sap Lake, Cambodia en-subtitle= kn-subtitle= en-abstract= kn-abstract=Villagers living on Tonlé Sap (TS) Lake have low incomes and no access to basic public services, such as waste management, domestic water, electricity, and health care. Knowledge of the villagers’ perceptions and the composition of the waste from their boathouses will contribute to constructing a waste collection system with community participation within the framework of waste prevention and reduction. This study surveyed residents living in boathouses in four floating villages on TS Lake, Cambodia, regarding their perceptions and boathouse waste composition to assess the status of plastic waste and the villagers’ environmental awareness and their willingness to participate in waste collection. The household waste survey sought to clarify the amount of plastic waste and other recyclable waste discharged from floating houses. The perception survey revealed that in the wet season, 36% of respondents disposed of plastic waste by open burning/dumping and 40% by discharge into TS Lake; in the dry season, 76% disposed of waste by open burning/dumping, and only 4% discharged waste into TS Lake. An analysis of the boathouse plastic waste composition showed that residents of the floating villages generated 40.21 g plastic waste/day/capita, which was much lower than 340 g/day/capita in the USA, 120 g/day/capita in China, and even 70 g/day/capita in Cambodian on average, but higher than the 10 g/day/capita in India. This study proposes a novel and valuable framework to estimate and determine the level of awareness of people in floating villages related to plastic pollution effects and waste components from boathouses. At the same time, the research results provide an essential scientific basis to be able to develop an effective waste collection system in the area of TS Lake. The proposed framework of this study will help the policy decision-makers in the TS Lake area and those in similar geographical regions facing similar problems. en-copyright= kn-copyright= en-aut-name=Habuer en-aut-sei=Habuer en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FujiwaraTakeshi en-aut-sei=Fujiwara en-aut-mei=Takeshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=VinSpoann en-aut-sei=Vin en-aut-mei=Spoann kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ChandaraPhat en-aut-sei=Chandara en-aut-mei=Phat kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TsukijiMakoto en-aut-sei=Tsukiji en-aut-mei=Makoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Environmental Management Course, Architecture, Civil Engineering and Environmental Management Program, School of Engineering, Okayama University kn-affil= affil-num=2 en-affil=Environmental Management Course, Architecture, Civil Engineering and Environmental Management Program, School of Engineering, Okayama University kn-affil= affil-num=3 en-affil=Department of Economic Development, Faculty of Development Studies, Royal University of Phnom Penh kn-affil= affil-num=4 en-affil=Department of Natural Resource Management and Development, Faculty of Development Studies, Royal University of Phnom Penh kn-affil= affil-num=5 en-affil=Environmental Management Course, Architecture, Civil Engineering and Environmental Management Program, School of Engineering, Okayama University kn-affil= en-keyword=Boathouse waste composition kn-keyword=Boathouse waste composition en-keyword=Cambodia kn-keyword=Cambodia en-keyword=Floating villages kn-keyword=Floating villages en-keyword=Perception survey kn-keyword=Perception survey en-keyword=Plastic waste kn-keyword=Plastic waste END start-ver=1.4 cd-journal=joma no-vol=58 cd-vols= no-issue= article-no= start-page=119 end-page=134 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Social Skills Required for Caregivers ――Outlook for Research Topics for Educational Practice―― kn-title=介護士に必要なソーシャルスキル――教育実践に向けた研究課題の展望―― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MIYAKESayumi en-aut-sei=MIYAKE en-aut-mei=Sayumi kn-aut-name=三宅沙侑美 kn-aut-sei=三宅 kn-aut-mei=沙侑美 aut-affil-num=1 ORCID= en-aut-name=YAMANOYoichi en-aut-sei=YAMANO en-aut-mei=Yoichi kn-aut-name=山野洋一 kn-aut-sei=山野 kn-aut-mei=洋一 aut-affil-num=2 ORCID= en-aut-name=TANAKATomoko en-aut-sei=TANAKA en-aut-mei=Tomoko kn-aut-name=田中共子 kn-aut-sei=田中 kn-aut-mei=共子 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院社会文化科学研究科 affil-num=2 en-affil= kn-affil=京都産業大学　教育支援研究開発センター affil-num=3 en-affil= kn-affil=岡山大学社会文化科学学域 END start-ver=1.4 cd-journal=joma no-vol=58 cd-vols= no-issue= article-no= start-page=71 end-page=89 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Exploring the Link Between Modern Household Amenities and Health in Vietnam en-subtitle= kn-subtitle= en-abstract= kn-abstract=　The correlation between the impact of the external and internal environment of a household on its occupants’ health has been well documented by various research studies. Yet a limitation of the literature is the prevalence of modern household basic amenities and occupant health, especially in Vietnam. This paper examines the impact of modern household basic amenities on occupant health by applying the Vietnam Household Standard Survey 2018. By applying the Tobit method, it is revealed that household amenities displayed a significant association with health outcomes. For instance, individuals residing in concrete houses or employing waste collection systems exhibited decreased illness likelihood. Handwashing with soap correlated with a diminished illness probability. Tobit analysis highlights internet accessibility as significant in reducing days of work incapacity (approximately 6 days less). Gender, residential location, and total income also impact workdays. Age and education exhibit inverse relationships with workdays missed. In essence, these findings contribute to the broader discourse on public health and underscore the importance of considering diverse factors, ranging from basic amenities to socio-economic indicators, in formulating comprehensive health policies and interventions. en-copyright= kn-copyright= en-aut-name=Do Thi Hoai Giang en-aut-sei=Do Thi Hoai Giang en-aut-mei= kn-aut-name=ド ティ ホアイ ジャン kn-aut-sei=ド ティ ホアイ ジャン kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院社会文化科学研究科 en-keyword=Modern household amenity kn-keyword=Modern household amenity en-keyword=occupant health kn-keyword=occupant health en-keyword=Vietnam kn-keyword=Vietnam en-keyword=Tobit regression kn-keyword=Tobit regression en-keyword=Logit model kn-keyword=Logit model END start-ver=1.4 cd-journal=joma no-vol=741 cd-vols= no-issue= article-no= start-page=151006 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=S-adenosylmethionine and S-adenosyl-L-homocysteine metabolism is involved in the sperm motility and in vitro fertility rate in mouse en-subtitle= kn-subtitle= en-abstract= kn-abstract=Increased fragmentation of sperm DNA has been implicated in male infertility. Folate deficiency results in impaired methionine synthesis, depletion of S-adenosylmethionine (SAM) levels, an increase in S-adenosyl-l-homocysteine (SAH) levels, and increased DNA fragmentation. Disruption of the dynamic balance between SAM and SAH may also contribute, although the details of this process are not yet fully understood. We investigated the localization of SAM, SAH, and S-adenosylhomocysteine hydrolase (SAHH), and whether SAM/SAH metabolism contributes to sperm motility and fertilization rate. SAM, SAH, and SAHH levels were assessed in the acrosome, midpiece, and tail of spermatozoa. Chemical inhibition of SAM/SAH metabolism and extracellular SAH significantly decreased the straight-line velocity (VSL), curvilinear velocity (VCL), and amplitude lateral head displacement (ALH) of sperm cells, which were thus unable to swim forward and perform oscillatory movements in place. This significantly reduced the fertilization rate. Therefore, the disruption of the SAM/SAH balance may contribute to male infertility. en-copyright= kn-copyright= en-aut-name=KawaiTomoko en-aut-sei=Kawai en-aut-mei=Tomoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FujimuraAtsushi en-aut-sei=Fujimura en-aut-mei=Atsushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Department of Cellular Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Cellular Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=SAM/SAH metabolism kn-keyword=SAM/SAH metabolism en-keyword=Sperm motility kn-keyword=Sperm motility en-keyword=Fertilization rate kn-keyword=Fertilization rate END start-ver=1.4 cd-journal=joma no-vol=125 cd-vols= no-issue= article-no= start-page=106672 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202502 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Resveratrol, a food-derived polyphenol, promotes Melanosomal degradation in skin fibroblasts through coordinated activation of autophagy, lysosomal, and antioxidant pathways en-subtitle= kn-subtitle= en-abstract= kn-abstract=Resveratrol, a polyphenol found in grapes and peanuts, is known for diverse biological activities, yet its effects on dermal hyperpigmentation (so-called dark spots) remain unexplored. We investigated resveratrol's ability to enhance melanosomal degradation in human dermal fibroblasts. At concentrations of 25-50 mu M, resveratrol increased autophagy as measured by microtubule-associated protein 1A/1B-light chain 3 (LC3)-II/LC3-I ratio and enhanced lysosomal activity as assessed by a lysosomal activity reporter system. RNA sequencing revealed upregulation of lysosomal and autophagy-related genes, including cathepsins. Furthermore, reporter assays showed resveratrol's activation of antioxidant response via nuclear factor erythroid 2-related factor 2 (NRF2)mediated, leading to upregulation of transcription factor EB/transcription factor E3 (TFEB/TFE3), master regulators of lysosomal function. In fibroblasts pre-loaded with melanosomes, resveratrol reduced melanosome content compared to control by day 3. The findings reveal the activation of interconnected autophagy, lysosomal, and antioxidant pathways by resveratrol, suggesting potential applications in functional foods targeting dermal hyperpigmentation. en-copyright= kn-copyright= en-aut-name=OkamotoSaki en-aut-sei=Okamoto en-aut-mei=Saki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KakimaruSaya en-aut-sei=Kakimaru en-aut-mei=Saya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KoreishiMayuko en-aut-sei=Koreishi en-aut-mei=Mayuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SakamotoMika en-aut-sei=Sakamoto en-aut-mei=Mika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NakamuraYoshimasa en-aut-sei=Nakamura en-aut-mei=Yoshimasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=AndoHideya en-aut-sei=Ando en-aut-mei=Hideya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=TsujinoYoshio en-aut-sei=Tsujino en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=SatohAyano en-aut-sei=Satoh en-aut-mei=Ayano kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=4 en-affil=National Institute of Genetics, ROIS kn-affil= affil-num=5 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=6 en-affil=Department of Applied Chemistry and Biotechnology, Okayama University of Science kn-affil= affil-num=7 en-affil=Graduate School of Science, Technology, and Innovation, Kobe University kn-affil= affil-num=8 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= en-keyword=Antioxidant kn-keyword=Antioxidant en-keyword=Lysosomes kn-keyword=Lysosomes en-keyword=Autophagy kn-keyword=Autophagy en-keyword=Resveratrol kn-keyword=Resveratrol en-keyword=Skin fibroblasts kn-keyword=Skin fibroblasts en-keyword=Bioactive compounds kn-keyword=Bioactive compounds END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=1 article-no= start-page=39 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250109 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Effectiveness of professional-identity-formation and clinical communication-skills programs on medical students' empathy in the COVID-19 context: comparison between pre-pandemic in-person classes and during-pandemic online classes en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background Enhancing students' empathy is critical in medical school education. The COVID-19 pandemic necessitated a shift from in-person to online classes. However, the effectiveness of online classes for enhancing medical students' empathy has not been investigated sufficiently and the evidence is limited. This study compared the effectiveness of enhancing empathy between pre-pandemic in-person classes and during-pandemic online classes among medical students in Japan using pre-pandemic and during-pandemic data.
Methods This is a retrospective observational study. This study measured students' empathy using the Japanese translation of the Jefferson Scale of Empathy-Student Version (JSE-S) before and after the special programs for professional identity formation and clinical communication among first- and second-year students who matriculated from 2015-2021. This study categorized the matriculation year groups as "pre-pandemic" and "during-pandemic" groups for the first- and second-year students. This study estimated the adjusted mean score differences of the JSE-S and 95% confidence intervals (CIs) from the pre- to post-program between the pre-pandemic and during-pandemic groups in the first and second years using linear regression analysis.
Results This study's participants included 653 first-year students and 562 second-year students. In the first year, the during-pandemic group had a significantly higher mean score difference from the pre- to post-program compared to the pre-pandemic group. The adjusted regression coefficient (95% CI) was 7.6 (5.7 - 9.5), with the pre-pandemic group as the reference. In the second year, there were no significant differences between the two groups.
Conclusions The results suggest that online classes are not inferior to in-person classes or even slightly better in enhancing medical students' empathy, which should be clarified by further studies. This study's findings have important implications for medical education and implementing hybrid class formats to enhance students' empathy. en-copyright= kn-copyright= en-aut-name=KataokaHitomi en-aut-sei=Kataoka en-aut-mei=Hitomi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TokinobuAkiko en-aut-sei=Tokinobu en-aut-mei=Akiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FujiiChikako en-aut-sei=Fujii en-aut-mei=Chikako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=WatanabeMayu en-aut-sei=Watanabe en-aut-mei=Mayu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ObikaMikako en-aut-sei=Obika en-aut-mei=Mikako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Center for Diversity and Inclusion, Okayama University Hospital kn-affil= affil-num=2 en-affil=Center for Diversity and Inclusion, Okayama University Hospital kn-affil= affil-num=3 en-affil=Center for Diversity and Inclusion, Okayama University Hospital kn-affil= affil-num=4 en-affil=Division of Kidney, Diabetes and Endocrine Diseases, Okayama University Hospital kn-affil= affil-num=5 en-affil=Department of General Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=COVID-19 pandemic kn-keyword=COVID-19 pandemic en-keyword=Empathy kn-keyword=Empathy en-keyword=Jefferson Scale of Empathy kn-keyword=Jefferson Scale of Empathy en-keyword=Medical students kn-keyword=Medical students en-keyword=Online class kn-keyword=Online class END start-ver=1.4 cd-journal=joma no-vol=126 cd-vols= no-issue=1 article-no= start-page=012901 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250102 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Dynamic domain motion enhancing electro-optic performance in ferroelectric films en-subtitle= kn-subtitle= en-abstract= kn-abstract=With the rapid advancement of information technology, there is a pressing need to develop ultracompact and energy-efficient thin-film-based electro-optic (EO) devices. A high EO coefficient in ferroelectric materials is crucial. However, substrate clamping can positively or negatively influence various physical properties, including the EO response of these films, thus complicating the development of next-generation thin-film-based devices. This study demonstrates that reversible dynamic domain motion, achieved through substrate clamping, significantly enhances the EO coefficient in epitaxial ferroelectric rhombohedral Pb(Zr, Ti)O3 thin films, where the (111) and (⁠ 111⁠) domains coexist with distinct optical axes. In principle, this approach can be applied to different film-substrate systems, thereby contributing to the advancement of sophisticated EO devices based on ferroelectrics. en-copyright= kn-copyright= en-aut-name=KondoShinya en-aut-sei=Kondo en-aut-mei=Shinya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OkamotoKazuki en-aut-sei=Okamoto en-aut-mei=Kazuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SakataOsami en-aut-sei=Sakata en-aut-mei=Osami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TeranishiTakashi en-aut-sei=Teranishi en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KishimotoAkira en-aut-sei=Kishimoto en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NagasakiTakanori en-aut-sei=Nagasaki en-aut-mei=Takanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YamadaTomoaki en-aut-sei=Yamada en-aut-mei=Tomoaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Department of Energy Engineering, Nagoya University kn-affil= affil-num=3 en-affil=Japan Synchrotron Radiation Research Institute (JASRI) kn-affil= affil-num=4 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=6 en-affil=Department of Energy Engineering, Nagoya University kn-affil= affil-num=7 en-affil=Department of Energy Engineering, Nagoya University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=18 cd-vols= no-issue=52 article-no= start-page=35202 end-page=35213 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241216 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Bright Quantum-Grade Fluorescent Nanodiamonds en-subtitle= kn-subtitle= en-abstract= kn-abstract=Optically accessible spin-active nanomaterials are promising as quantum nanosensors for probing biological samples. However, achieving bioimaging-level brightness and high-quality spin properties for these materials is challenging and hinders their application in quantum biosensing. Here, we demonstrate bright fluorescent nanodiamonds (NDs) containing 0.6–1.3-ppm negatively charged nitrogen-vacancy (NV) centers by spin-environment engineering via enriching spin-less 12C-carbon isotopes and reducing substitutional nitrogen spin impurities. The NDs, readily introduced into cultured cells, exhibited improved optically detected magnetic resonance (ODMR) spectra; peak splitting (E) was reduced by 2–3 MHz, and microwave excitation power required was 20 times lower to achieve a 3% ODMR contrast, comparable to that of conventional type-Ib NDs. They show average spin-relaxation times of T1 = 0.68 ms and T2 = 3.2 μs (1.6 ms and 5.4 μs maximum) that were 5- and 11-fold longer than those of type-Ib, respectively. Additionally, the extended T2 relaxation times of these NDs enable shot-noise-limited temperature measurements with a sensitivity of approximately 0.28K/√Hz. The combination of bulk-like NV spin properties and enhanced fluorescence significantly improves the sensitivity of ND-based quantum sensors for biological applications. en-copyright= kn-copyright= en-aut-name=OshimiKeisuke en-aut-sei=Oshimi en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IshiwataHitoshi en-aut-sei=Ishiwata en-aut-mei=Hitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NakashimaHiromu en-aut-sei=Nakashima en-aut-mei=Hiromu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MandićSara en-aut-sei=Mandić en-aut-mei=Sara kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KobayashiHina en-aut-sei=Kobayashi en-aut-mei=Hina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TeramotoMinori en-aut-sei=Teramoto en-aut-mei=Minori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=TsujiHirokazu en-aut-sei=Tsuji en-aut-mei=Hirokazu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NishibayashiYoshiki en-aut-sei=Nishibayashi en-aut-mei=Yoshiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=ShikanoYutaka en-aut-sei=Shikano en-aut-mei=Yutaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=AnToshu en-aut-sei=An en-aut-mei=Toshu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=FujiwaraMasazumi en-aut-sei=Fujiwara en-aut-mei=Masazumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= affil-num=1 en-affil=Department of Chemistry, Graduate School of Life, Environmental, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=The National Institutes for Quantum Science and Technology (QST), Institute for Quantum Life Science (iQLS) kn-affil= affil-num=3 en-affil=Department of Chemistry, Graduate School of Life, Environmental, Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Department of Chemistry, Graduate School of Life, Environmental, Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Department of Chemistry, Graduate School of Life, Environmental, Natural Science and Technology, Okayama University kn-affil= affil-num=6 en-affil=Advanced Materials Laboratory, Sumitomo Electric Industries, Ltd. kn-affil= affil-num=7 en-affil=Advanced Materials Laboratory, Sumitomo Electric Industries, Ltd. kn-affil= affil-num=8 en-affil=Advanced Materials Laboratory, Sumitomo Electric Industries, Ltd. kn-affil= affil-num=9 en-affil=Institute of Systems and Information Engineering, University of Tsukuba kn-affil= affil-num=10 en-affil=School of Materials Science, Japan Advanced Institute of Science and Technology kn-affil= affil-num=11 en-affil=Department of Chemistry, Graduate School of Life, Environmental, Natural Science and Technology, Okayama University kn-affil= en-keyword=nanodiamonds kn-keyword=nanodiamonds en-keyword=nitrogen-vacancy centers kn-keyword=nitrogen-vacancy centers en-keyword=spins kn-keyword=spins en-keyword=spin-relaxation times kn-keyword=spin-relaxation times en-keyword=quantum biosensor kn-keyword=quantum biosensor en-keyword=cellular probes kn-keyword=cellular probes END start-ver=1.4 cd-journal=joma no-vol=2024 cd-vols= no-issue=12 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=202412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Multi-dimensional optimisation of the scanning strategy for the LiteBIRD space mission en-subtitle= kn-subtitle= en-abstract= kn-abstract=Large angular scale surveys in the absence of atmosphere are essential for measuring the primordial B-mode power spectrum of the Cosmic Microwave Background (CMB). Since this proposed measurement is about three to four orders of magnitude fainter than the temperature anisotropies of the CMB, in-flight calibration of the instruments and active suppression of systematic effects are crucial. We investigate the effect of changing the parameters of the scanning strategy on the in-flight calibration effectiveness, the suppression of the systematic effects themselves, and the ability to distinguish systematic effects by null-tests. Next-generation missions such as LiteBIRD, modulated by a Half-Wave Plate (HWP), will be able to observe polarisation using a single detector, eliminating the need to combine several detectors to measure polarisation, as done in many previous experiments and hence avoiding the consequent systematic effects. While the HWP is expected to suppress many systematic effects, some of them will remain. We use an analytical approach to comprehensively address the mitigation of these systematic effects and identify the characteristics of scanning strategies that are the most effective for implementing a variety of calibration strategies in the multi-dimensional space of common spacecraft scan parameters. We verify that LiteBIRD's standard configuration yields good performance on the metrics we studied. We also present Falcons.jl, a fast spacecraft scanning simulator that we developed to investigate this scanning parameter space. en-copyright= kn-copyright= en-aut-name=TakaseY. en-aut-sei=Takase en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=VacherL. en-aut-sei=Vacher en-aut-mei=L. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IshinoH. en-aut-sei=Ishino en-aut-mei=H. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=PatanchonG. en-aut-sei=Patanchon en-aut-mei=G. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MontierL. en-aut-sei=Montier en-aut-mei=L. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SteverS.L. en-aut-sei=Stever en-aut-mei=S.L. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=IshizakaK. en-aut-sei=Ishizaka en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NaganoY. 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en-aut-sei=Scott en-aut-mei=D. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=92 ORCID= en-aut-name=SekimotoY. en-aut-sei=Sekimoto en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=93 ORCID= en-aut-name=ShiraishiM. en-aut-sei=Shiraishi en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=94 ORCID= en-aut-name=SignorelliG. en-aut-sei=Signorelli en-aut-mei=G. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=95 ORCID= en-aut-name=SullivanR.M. en-aut-sei=Sullivan en-aut-mei=R.M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=96 ORCID= en-aut-name=TakakuraH. en-aut-sei=Takakura en-aut-mei=H. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=97 ORCID= en-aut-name=TerenziL. en-aut-sei=Terenzi en-aut-mei=L. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=98 ORCID= en-aut-name=TomasiM. en-aut-sei=Tomasi en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=99 ORCID= en-aut-name=TristramM. en-aut-sei=Tristram en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=100 ORCID= en-aut-name=van TentB. en-aut-sei=van Tent en-aut-mei=B. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=101 ORCID= en-aut-name=VielvaP. en-aut-sei=Vielva en-aut-mei=P. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=102 ORCID= en-aut-name=WehusI.K. en-aut-sei=Wehus en-aut-mei=I.K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=103 ORCID= en-aut-name=WestbrookB. en-aut-sei=Westbrook en-aut-mei=B. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=104 ORCID= en-aut-name=Weymann-DespresG. en-aut-sei=Weymann-Despres en-aut-mei=G. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=105 ORCID= en-aut-name=WollackE.J. en-aut-sei=Wollack en-aut-mei=E.J. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=106 ORCID= en-aut-name=ZannoniM. en-aut-sei=Zannoni en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=107 ORCID= en-aut-name=ZhouY. en-aut-sei=Zhou en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=108 ORCID= affil-num=1 en-affil=Okayama University, Department of Physics kn-affil= affil-num=2 en-affil=International School for Advanced Studies (SISSA) kn-affil= affil-num=3 en-affil=Okayama University, Department of Physics kn-affil= affil-num=4 en-affil=ILANCE, CNRS, University of Tokyo International Research Laboratory kn-affil= affil-num=5 en-affil=IRAP, Université de Toulouse, CNRS, CNES, UPS kn-affil= affil-num=6 en-affil=Okayama University, Department of Physics kn-affil= affil-num=7 en-affil=Okayama University, Department of Physics kn-affil= affil-num=8 en-affil=Okayama University, Department of Physics kn-affil= affil-num=9 en-affil=Université Paris Cité, CNRS, Astroparticule et Cosmologie kn-affil= affil-num=10 en-affil=IRAP, Université de Toulouse, CNRS, CNES, UPS kn-affil= affil-num=11 en-affil=The University of Tokyo, Department of Physics kn-affil= affil-num=12 en-affil=Dipartimento di Fisica, Università di Roma Tor Vergata kn-affil= affil-num=13 en-affil=International School for Advanced Studies (SISSA) kn-affil= affil-num=14 en-affil=Dipartimento di Fisica e Scienze della Terra, Università di Ferrara kn-affil= affil-num=15 en-affil=IRAP, Université de Toulouse, CNRS, CNES, UPS kn-affil= affil-num=16 en-affil=Instituto de Fisica de Cantabria (IFCA, CSIC-UC) kn-affil= affil-num=17 en-affil=Dipartimento di Fisica e Astronomia "G. Galilei", Università degli Studi di Padova kn-affil= affil-num=18 en-affil=School of Physics, Indian Institute of Science Education and Research Thiruvananthapuram kn-affil= affil-num=19 en-affil=Dipartimento di Fisica, Università degli Studi di Milano kn-affil= affil-num=20 en-affil=Dipartimento di Fisica e Scienze della Terra, Università di Ferrara kn-affil= affil-num=21 en-affil=Dipartimento di Fisica e Scienze della Terra, Università di Ferrara kn-affil= affil-num=22 en-affil=School of Physics and Astronomy, Cardiff University kn-affil= affil-num=23 en-affil=INFN Sezione di Ferrara kn-affil= affil-num=24 en-affil=IRAP, Université de Toulouse, CNRS, CNES, UPS kn-affil= affil-num=25 en-affil=International School for Advanced Studies (SISSA) kn-affil= affil-num=26 en-affil=Instituto de Fisica de Cantabria (IFCA, CSIC-UC) kn-affil= affil-num=27 en-affil=Jodrell Bank Centre for Astrophysics, Department of Physics and Astronomy, School of Natural Sciences, The University of Manchester kn-affil= affil-num=28 en-affil=Centre Spatial de Liège, Université de Liège kn-affil= affil-num=29 en-affil=Dipartimento di Fisica, Università La Sapienza kn-affil= affil-num=30 en-affil=Dipartimento di Fisica, Università La Sapienza kn-affil= affil-num=31 en-affil=INAF, OAS Bologna kn-affil= affil-num=32 en-affil=Dipartimento di Fisica, Università La Sapienza kn-affil= affil-num=33 en-affil=Dipartimento di Fisica, Università La Sapienza kn-affil= affil-num=34 en-affil=Institute of Particle and Nuclear Studies (IPNS), High Energy Accelerator Research Organization (KEK) kn-affil= affil-num=35 en-affil=CNRS-UCB International Research Laboratory, Centre Pierre Binétruy, UMI2007 kn-affil= affil-num=36 en-affil=INFN Sezione Milano Bicocca kn-affil= affil-num=37 en-affil=Max Planck Institute for Astrophysics kn-affil= affil-num=38 en-affil=Institute of Theoretical Astrophysics, University of Oslo kn-affil= affil-num=39 en-affil=Université Paris Cité, CNRS, Astroparticule et Cosmologie kn-affil= affil-num=40 en-affil=INAF, OAS Bologna kn-affil= affil-num=41 en-affil=Institute of Theoretical Astrophysics, University of Oslo kn-affil= affil-num=42 en-affil=Dipartimento di Fisica e Scienze della Terra, Università di Ferrara kn-affil= affil-num=43 en-affil=Institute of Theoretical Astrophysics, University of Oslo kn-affil= affil-num=44 en-affil=University of Milano Bicocca, Physics Department kn-affil= affil-num=45 en-affil=International Center for Quantum-field Measurement Systems for Studies of the Universe and Particles (QUP), High Energy Accelerator Research Organization (KEK) kn-affil= affil-num=46 en-affil=School of Physics and Astronomy, Cardiff University kn-affil= affil-num=47 en-affil=Instituto de Fisica de Cantabria (IFCA, CSIC-UC) kn-affil= affil-num=48 en-affil=Institute of Theoretical Astrophysics, University of Oslo kn-affil= affil-num=49 en-affil=Instituto de Astrofísica de Canarias kn-affil= affil-num=50 en-affil=INAF, OAS Bologna kn-affil= affil-num=51 en-affil=International Center for Quantum-field Measurement Systems for Studies of the Universe and Particles (QUP), High Energy Accelerator Research Organization (KEK) kn-affil= affil-num=52 en-affil=Université Paris-Saclay, CNRS/IN2P3, IJCLab kn-affil= affil-num=53 en-affil=Department of Physics and Astronomy, University of British Columbia kn-affil= affil-num=54 en-affil=Okayama University, Department of Physics kn-affil= affil-num=55 en-affil=Institute of Particle and Nuclear Studies (IPNS), High Energy Accelerator Research Organization (KEK) kn-affil= affil-num=56 en-affil=Dipartimento di Fisica, Università La Sapienza kn-affil= affil-num=57 en-affil=INFN Sezione di Ferrara kn-affil= affil-num=58 en-affil=Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI), UTIAS, The University of Tokyo kn-affil= affil-num=59 en-affil=Dipartimento di Fisica e Scienze della Terra, Università di Ferrara kn-affil= affil-num=60 en-affil=Laboratoire de Physique de l'École Normale Supérieure, ENS, Université PSL, CNRS, Sorbonne Université, Université de Paris kn-affil= affil-num=61 en-affil=University of California, San Diego, Department of Physics kn-affil= affil-num=62 en-affil=Aurora Technology for the European Space Agency kn-affil= affil-num=63 en-affil=Space Science Data Center, Italian Space Agency kn-affil= affil-num=64 en-affil=Université Paris-Saclay, CNRS, Institut d'Astrophysique Spatiale kn-affil= affil-num=65 en-affil=Instituto de Fisica de Cantabria (IFCA, CSIC-UC) kn-affil= affil-num=66 en-affil=Dipartimento di Fisica, Università La Sapienza kn-affil= affil-num=67 en-affil=Dipartimento di Fisica e Astronomia "G. Galilei", Università degli Studi di Padova kn-affil= affil-num=68 en-affil=Japan Aerospace Exploration Agency (JAXA), Institute of Space and Astronautical Science (ISAS) kn-affil= affil-num=69 en-affil=Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI), UTIAS, The University of Tokyo kn-affil= affil-num=70 en-affil=Dipartimento di Fisica, Università La Sapienza kn-affil= affil-num=71 en-affil=Dipartimento di Fisica, Università di Roma Tor Vergata kn-affil= affil-num=72 en-affil=Max Planck Institute for Astrophysics kn-affil= affil-num=73 en-affil=INAF, OAS Bologna kn-affil= affil-num=74 en-affil=IRAP, Université de Toulouse, CNRS, CNES, UPS kn-affil= affil-num=75 en-affil=Japan Aerospace Exploration Agency (JAXA), Institute of Space and Astronautical Science (ISAS) kn-affil= affil-num=76 en-affil=Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI), UTIAS, The University of Tokyo kn-affil= affil-num=77 en-affil=Dipartimento di Fisica, Università La Sapienza kn-affil= affil-num=78 en-affil=Japan Aerospace Exploration Agency (JAXA), Institute of Space and Astronautical Science (ISAS) kn-affil= affil-num=79 en-affil=Japan Aerospace Exploration Agency (JAXA), Institute of Space and Astronautical Science (ISAS) kn-affil= affil-num=80 en-affil=Okayama University, Department of Physics kn-affil= affil-num=81 en-affil=Dipartimento di Fisica e Scienze della Terra, Università di Ferrara kn-affil= affil-num=82 en-affil=INAF, OAS Bologna kn-affil= affil-num=83 en-affil=Dipartimento di Fisica, Università La Sapienza kn-affil= affil-num=84 en-affil=INFN Sezione di Pisa kn-affil= affil-num=85 en-affil=Space Science Data Center, Italian Space Agency kn-affil= affil-num=86 en-affil=Istituto Nazionale di Fisica Nucleare-aboratori Nazionali di Frascati (INFN-LNF) kn-affil= affil-num=87 en-affil=Dipartimento di Fisica e Scienze della Terra, Università di Ferrara kn-affil= affil-num=88 en-affil=Instituto de Fisica de Cantabria (IFCA, CSIC-UC) kn-affil= affil-num=89 en-affil=Dipartimento di Fisica, Università di Roma Tor Vergata kn-affil= affil-num=90 en-affil=Instituto de Fisica de Cantabria (IFCA, CSIC-UC) kn-affil= affil-num=91 en-affil=Suwa University of Science kn-affil= affil-num=92 en-affil=Department of Physics and Astronomy, University of British Columbia kn-affil= affil-num=93 en-affil=Japan Aerospace Exploration Agency (JAXA), Institute of Space and Astronautical Science (ISAS) kn-affil= affil-num=94 en-affil=Suwa University of Science kn-affil= affil-num=95 en-affil=Dipartimento di Fisica, Università di Pisa kn-affil= affil-num=96 en-affil=Department of Physics and Astronomy, University of British Columbia kn-affil= affil-num=97 en-affil=Japan Aerospace Exploration Agency (JAXA), Institute of Space and Astronautical Science (ISAS) kn-affil= affil-num=98 en-affil=INAF, OAS Bologna kn-affil= affil-num=99 en-affil=Dipartimento di Fisica, Università degli Studi di Milano kn-affil= affil-num=100 en-affil=Université Paris-Saclay, CNRS/IN2P3, IJCLab kn-affil= affil-num=101 en-affil=Université Paris-Saclay, CNRS/IN2P3, IJCLab kn-affil= affil-num=102 en-affil=Instituto de Fisica de Cantabria (IFCA, CSIC-UC) kn-affil= affil-num=103 en-affil=Institute of Theoretical Astrophysics, University of Oslo kn-affil= affil-num=104 en-affil=University of California, Berkeley, Department of Physics, Berkeley kn-affil= affil-num=105 en-affil=Université Paris-Saclay, CNRS/IN2P3, IJCLab kn-affil= affil-num=106 en-affil=NASA Goddard Space Flight Center kn-affil= affil-num=107 en-affil=University of Milano Bicocca, Physics Department kn-affil= affil-num=108 en-affil=International Center for Quantum-field Measurement Systems for Studies of the Universe and Particles (QUP), High Energy Accelerator Research Organization (KEK) kn-affil= en-keyword=CMBR experiments kn-keyword=CMBR experiments en-keyword=CMBR polarisation kn-keyword=CMBR polarisation en-keyword=gravitational waves and CMBR polarization kn-keyword=gravitational waves and CMBR polarization END start-ver=1.4 cd-journal=joma no-vol=222 cd-vols= no-issue= article-no= start-page=115374 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Environmental water in Kolkata is suitable for the survival of Vibrio cholerae O1 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Many patients with cholera emerge in Kolkata, India throughout the year. Such emergency indicates that cholera toxin-producing Vibrio cholerae O1 (toxigenic V. cholerae O1) are widespread in Kolkata. This suggests that the suitable conditions for replication of toxigenic V. cholerae O1 is provided in Kolkata. In previous studies, we found that the replication rate of toxigenic V. cholerae O1 is low in the low ionic aqueous solution. Then we measured the ion concentration in the environmental water of Kolkata. As a control, we measured them in Japanese environmental water. The ion concentration in the environmental water of Kolkata was significantly high. Then, we examined the survival of toxigenic V. cholerae O1 in groundwater from Kolkata and found that V. cholerae O1 survive for long time in the solution but not in the solution diluted with Milli Q water. In addition, we found that V. cholerae O1 proliferated in environmental water of Kolkata to which a small amount of nutrient was added, but did not grow in the environmental water diluted with water to which the same amount of nutrient was added. These results indicate that the environmental water from Kolkata is suitable for survival of V. cholerae O1. en-copyright= kn-copyright= en-aut-name=TakahashiEizo en-aut-sei=Takahashi en-aut-mei=Eizo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KitaharaKei en-aut-sei=Kitahara en-aut-mei=Kei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MiyoshiShin-ichi en-aut-sei=Miyoshi en-aut-mei=Shin-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ChowdhuryGoutam en-aut-sei=Chowdhury en-aut-mei=Goutam kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MukhopadhyayAsish K. en-aut-sei=Mukhopadhyay en-aut-mei=Asish K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=DuttaShanta en-aut-sei=Dutta en-aut-mei=Shanta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=OchiSadayuki en-aut-sei=Ochi en-aut-mei=Sadayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=OkamotoKeinosuke en-aut-sei=Okamoto en-aut-mei=Keinosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Collaborative Research Center of Okayama University for Infectious Diseases in India kn-affil= affil-num=2 en-affil=Collaborative Research Center of Okayama University for Infectious Diseases in India kn-affil= affil-num=3 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences of Okayama University kn-affil= affil-num=4 en-affil=National Institute of Cholera and Enteric Diseases kn-affil= affil-num=5 en-affil=National Institute of Cholera and Enteric Diseases kn-affil= affil-num=6 en-affil=National Institute of Cholera and Enteric Diseases kn-affil= affil-num=7 en-affil=Department of Health Pharmacy, Yokohama University of Pharmacy kn-affil= affil-num=8 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences of Okayama University kn-affil= en-keyword=Environmental water kn-keyword=Environmental water en-keyword=Ion kn-keyword=Ion en-keyword=Prevalence kn-keyword=Prevalence en-keyword=Survival kn-keyword=Survival en-keyword=Vibrio cholerae kn-keyword=Vibrio cholerae END start-ver=1.4 cd-journal=joma no-vol=391 cd-vols= no-issue= article-no= start-page=158 end-page=176 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250215 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Magnesium isotope composition of volcanic rocks from cold and warm subduction zones: Implications for the recycling of subducted serpentinites and carbonates en-subtitle= kn-subtitle= en-abstract= kn-abstract=Magnesium (Mg) isotopes are regarded as a sensitive tracer to the contribution from subducted serpentinites and carbonates. However, the source, distribution, and controlling factors of the Mg isotope composition of arc magmas remain unclear. In this study, we investigated the intra-arc and inter-arc variations in Mg isotope compositions of volcanic rocks from two typical cold subduction zones [NE Japan (NEJ) and Izu arcs] and a typical hot subduction zone [SW Japan (SWJ) arc] to address the question. The volcanic rocks from the frontal-arc regions of NEJ and Izu have isotopically heavy Mg (δ26Mg = –0.20 to –0.08 ‰) compared to the mantle-like δ26Mg values of most of volcanic rocks from SWJ and the rear regions of NEJ and Izu arcs (–0.28 to –0.17 ‰). It is also worth noting that NEJ arc includes samples with δ26Mg values (–0.61 to –0.39 ‰) significantly lower than the mantle, but similar to the < 110 Ma intra-continental basalts from eastern China, which is the first observation in modern arc rocks. No obvious effects of post-eruptive alteration, fractional crystallization, partial melting, or the addition of silicate-rich sediment and oceanic crust components could be identified in the Mg isotope compositions of these volcanic rocks. By contrast, the correlations between the δ26Mg values and the proxy for serpentinite component (i.e., 11B/10B and Nb/B ratios) indicate that the component exerts a strong control on the Mg-isotopic signature of these arc rocks. Considering metamorphic reactions in subduction lithologies under P-T conditions postulated for these arcs, the variations in δ26Mg values of these arc magmas are unlikely to have been controlled by dehydration of serpentinites in subducted oceanic lithosphere (slab serpentinite). Instead, the high-δ26Mg values of frontal-arc rocks are delivered by the fluids from serpentinite formed in the lowermost part of the sub-arc mantle (mantle wedge serpentinite) in channelized flow. Comparatively, such a high-δ26Mg signature is invisible in volcanic rocks from rear-arc regions of NEJ and Izu, and the entire SWJ, suggesting that the major Mg carriers in subducted serpentinites (e.g., talc, chlorite, and serpentine) were broken down completely before subducted slabs reached the depth beneath these volcanoes. Moreover, the volcanic rocks with low δ26Mg values from the rear arc of NEJ are characterized by high La/Yb and U/Nb ratios as well as low Ti/Eu, Ti/Ti*, and Hf/Hf* ratios, suggesting the involvements of carbonates in their magma sources. The quantitative modeling suggests that < 20 % of sedimentary carbonate (dolomite) was recycled into their mantle source, revealing that Mg-rich carbonate could be incorporated into a deep mantle wedge at rear-arc depths of 150–400 km in subduction zones. en-copyright= kn-copyright= en-aut-name=ZhangWei en-aut-sei=Zhang en-aut-mei=Wei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KitagawaHiroshi en-aut-sei=Kitagawa en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HuangFang en-aut-sei=Huang en-aut-mei=Fang kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=The Pheasant Memorial Laboratory for Geochemistry and Cosmochemistry, Institute for Planetary Materials, Okayama University kn-affil= affil-num=2 en-affil=The Pheasant Memorial Laboratory for Geochemistry and Cosmochemistry, Institute for Planetary Materials, Okayama University kn-affil= affil-num=3 en-affil=CAS Key Laboratory of Crust-Mantle Materials and Environments, School of Earth and Space Sciences, University of Science and Technology of China kn-affil= en-keyword=Magnesium isotopes kn-keyword=Magnesium isotopes en-keyword=Arc magmas kn-keyword=Arc magmas en-keyword=Mantle wedge serpentinite kn-keyword=Mantle wedge serpentinite en-keyword=Slab serpentinite kn-keyword=Slab serpentinite en-keyword=Carbonate recycle kn-keyword=Carbonate recycle END start-ver=1.4 cd-journal=joma no-vol=31 cd-vols= no-issue=2 article-no= start-page=102554 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241105 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Human Papillomavirus vaccination awareness and uptake among healthcare students in Japan en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: The vaccination rate for HPV (Human Papillomavirus) has remained significantly low in Japan because of the administrative suspension of active recommendation. This study investigates the awareness and uptake of the HPV vaccine among healthcare students in Japan following the reinstatement of active recommendation for young women in April 2022.
Methods: A web-based survey was administered to 2567 healthcare students from Okayama and Shujitsu Universities in Japan in July 2023. The survey assessed participants' backgrounds, immunization status, awareness of vaccine recommendations, and knowledge of cervical cancer across various demographics, including sex, academic year, and department (Medicine, Health Science, Pharmaceutical, and Dentistry).
Results: The response rate was 36.3 % (933 students; 181 male, 739 female, and 13 unspecified gender). The overall immunization rate among female students was 55.6 %, with higher rates observed in medical (73.8 %) and dental (63.0 %) students. Awareness of the government's change in vaccine recommendation was notably high among female and senior male students. Over half of the female students (54.7 %) reported receiving vaccinations based on their parents' advice. Among those unvaccinated but interested in future immunization, concerns about adverse reactions (47.4 %) and challenges in scheduling vaccinations (29.1 %) were predominant.
Conclusion: Healthcare students exhibited a higher HPV vaccination rate than the general population. Ongoing education to improve vaccine literacy is crucial for augmenting HPV vaccination rates in Japan. en-copyright= kn-copyright= en-aut-name=ShimbeMadoka en-aut-sei=Shimbe en-aut-mei=Madoka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OtsukaYuki en-aut-sei=Otsuka en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HagiyaHideharu en-aut-sei=Hagiya en-aut-mei=Hideharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamadaYoichi en-aut-sei=Yamada en-aut-mei=Yoichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Infectious Diseases, Okayama University Hospital kn-affil= affil-num=4 en-affil=School of Pharmacy, Shujitsu University kn-affil= affil-num=5 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=Cervical cancer kn-keyword=Cervical cancer en-keyword=Human Papillomavirus kn-keyword=Human Papillomavirus en-keyword=Immunization kn-keyword=Immunization en-keyword=Vaccine literacy kn-keyword=Vaccine literacy END start-ver=1.4 cd-journal=joma no-vol=101 cd-vols= no-issue=5 article-no= start-page=1030 end-page=1037.e5 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202505 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Short- and longer-term learning effects from virtual scale endoscopy videos: a useful tool for colorectal lesion size estimation (with videos) en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background and Aims: Accurate assessment of colorectal polyp size is crucial for determining treatment and surveillance policies. However, visual estimation of lesion diameter is often inaccurate, making simple and effective educational tools essential. We aimed to evaluate the learning effects of virtual scale endoscopy (VSE).
Methods: Thirty-three endoscopists first watched prelearning videos for SET1. They then estimated the diameters of 20 lesions and referred to instructional videos with VSE for self-study. Subsequently, they watched the postlearning videos for SET2 and estimated the lesion diameters. The error between the estimated and correct lesion sizes of both sets was compared. To evaluate longer-term learning effects, participants answered SET3 and SET4, which consisted of the same questions as SET2 and SET1, respectively, but 2 to 3 months later without watching the instructional video for SET2.
Results: The error in the participants’ estimation of the correct lesion diameter improved from SET1 to SET2 (34.7 ± 6.6 mm vs 30.7 ± 7.7 mm, P = .048), with a significant learning effect and error improvement specifically among nonexperts (35.2 ± 5.3 mm vs 30 ± 6.8 mm, P = .028). In SET3 and SET4, participants’ errors indicated that the learning effect was well maintained (SET2 vs SET3: 30.7 ± 7.7 mm vs 28.6 ± 7.2 mm [P = .1]; SET1 vs SET4: 34.7 ± 6.6 mm vs 31.7 ± 7.1 mm [P = .025]).
Conclusions: VSE videos are a valuable learning tool for estimating lesion diameter, particularly for novice endoscopists, both in the short and longer term. en-copyright= kn-copyright= en-aut-name=HiraiRyosuke en-aut-sei=Hirai en-aut-mei=Ryosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KinugasaHideaki en-aut-sei=Kinugasa en-aut-mei=Hideaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IshiguroMikako en-aut-sei=Ishiguro en-aut-mei=Mikako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ToyosawaJunki en-aut-sei=Toyosawa en-aut-mei=Junki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=AoyamaYuki en-aut-sei=Aoyama en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=IgawaShoko en-aut-sei=Igawa en-aut-mei=Shoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YamasakiYasushi en-aut-sei=Yamasaki en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=InokuchiToshihiro en-aut-sei=Inokuchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=TakaharaMasahiro en-aut-sei=Takahara en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=KawanoSeiji en-aut-sei=Kawano en-aut-mei=Seiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=HiraokaSakiko en-aut-sei=Hiraoka en-aut-mei=Sakiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=OtsukaMotoyuki en-aut-sei=Otsuka en-aut-mei=Motoyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= affil-num=1 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=10 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=11 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=12 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=1 article-no= start-page=48 end-page=53 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241209 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Effectiveness of oral health care intervention for stroke patients following the introduction of Oral Health Assessment Tool en-subtitle= kn-subtitle= en-abstract= kn-abstract=Aim: This study aimed to evaluate the effectiveness of oral health assessment tools in facilitating oral health care interventions by dental care providers for acute stroke patients within 48 h of admission, following a reform of the nursing system.
Methods: Data were gathered from a retrospective cohort study conducted at a stroke center, comparing 10 months before and after the implementation of the reformed system, with a 2-month interval. Parameters assessed included stroke type, severity measured using the National Institutes of Health Stroke Scale, stroke history, stroke-related factors, number of teeth, hospitalization cost and duration, occurrence of fever and pneumonia, stroke treatment, days from admission to dental intervention, and intervention frequency.
Results: Implementation of the new system significantly reduced the time before dental intervention (P < 0.001), increased the frequency of interventions (P < 0.001), and allowed for the management of more severe cases (P = 0.007). However, there was a slight increase in the occurrence of fevers and the days of fever (P = 0.039 and P = 0.015, respectively). Multiple regression analysis showed that fever days were positively correlated with stroke severity and the number of days from admission to dental intervention (P < 0.001 and P = 0.013, respectively). Even after propensity score matching adjusting for stroke severity, these associations persisted. Additional multiple regression analysis was performed after this, but fever days were positively correlated with stroke severity and sex (P < 0.001 and P = 0.008, respectively), as well as with the presence of other factors affecting the occurrence of fever.
Conclusions: Although the frequency and duration of fevers increased slightly, this approach, incorporating oral health assessment tools, made it possible to provide early dental intervention, particularly for patients with severe strokes. Geriatr Gerontol Int 2025; 25: 48–53. en-copyright= kn-copyright= en-aut-name=MatsunagaKazuyuki en-aut-sei=Matsunaga en-aut-mei=Kazuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=Yoshida‐TsuboiAyaka en-aut-sei=Yoshida‐Tsuboi en-aut-mei=Ayaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=InoharaKen en-aut-sei=Inohara en-aut-mei=Ken kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YoshidaYasuko en-aut-sei=Yoshida en-aut-mei=Yasuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NakahamaKanako en-aut-sei=Nakahama en-aut-mei=Kanako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SasakiKazuki en-aut-sei=Sasaki en-aut-mei=Kazuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SoudaFumie en-aut-sei=Souda en-aut-mei=Fumie kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TerasawaYuka en-aut-sei=Terasawa en-aut-mei=Yuka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=ShimoeYutaka en-aut-sei=Shimoe en-aut-mei=Yutaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=Takeuchi‐HatanakaKazu en-aut-sei=Takeuchi‐Hatanaka en-aut-mei=Kazu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=YamamotoTadashi en-aut-sei=Yamamoto en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=OmoriKazuhiro en-aut-sei=Omori en-aut-mei=Kazuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=KohriyamaTatsuo en-aut-sei=Kohriyama en-aut-mei=Tatsuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=TakashibaShogo en-aut-sei=Takashiba en-aut-mei=Shogo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= affil-num=1 en-affil=Department of Periodontics and Endodontics, Division of Dentistry, Okayama University Hospital kn-affil= affil-num=2 en-affil=Department of Periodontics and Endodontics, Division of Dentistry, Okayama University Hospital kn-affil= affil-num=3 en-affil=Brain Attack Center, Ota Memorial Hospital kn-affil= affil-num=4 en-affil=Brain Attack Center, Ota Memorial Hospital kn-affil= affil-num=5 en-affil=Brain Attack Center, Ota Memorial Hospital kn-affil= affil-num=6 en-affil=Brain Attack Center, Ota Memorial Hospital kn-affil= affil-num=7 en-affil=Brain Attack Center, Ota Memorial Hospital kn-affil= affil-num=8 en-affil=Brain Attack Center, Ota Memorial Hospital kn-affil= affil-num=9 en-affil=Brain Attack Center, Ota Memorial Hospital kn-affil= affil-num=10 en-affil=Department of Periodontics and Endodontics, Division of Dentistry, Okayama University Hospital kn-affil= affil-num=11 en-affil=The Center for Graduate Medical Education (Dental Division), Okayama University Hospital kn-affil= affil-num=12 en-affil=Department of Pathophysiology – Periodontal Science, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=13 en-affil=Brain Attack Center, Ota Memorial Hospital kn-affil= affil-num=14 en-affil=Department of Pathophysiology – Periodontal Science, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=acute stroke kn-keyword=acute stroke en-keyword=dental intervention kn-keyword=dental intervention en-keyword=medical and dental cooperation kn-keyword=medical and dental cooperation en-keyword=oral health assessment tool kn-keyword=oral health assessment tool en-keyword=severity kn-keyword=severity END start-ver=1.4 cd-journal=joma no-vol=4 cd-vols= no-issue= article-no= start-page=53 end-page=63 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=What is education for sustainable development?: From the perspective of international legal history kn-title=持続可能な開発のための教育とは―国際法制史の視点から― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Throughout the history of international law, sustainable development has always been acknowledged as a global responsibility. In recent years, as global environmental concerns have escalated, this responsibility has become increasingly crucial. To fulfil this mandate, education policies must transcend national boundaries. Specifically, in light of pressing global environmental issues such as climate change, education on sustainable development is pivotal for the well-being of future generations. To delve deeper into this significance, the author examines the emergence of ESD (Education for Sustainable Development), its accomplishments, and the challenges the world is currently grappling with. en-copyright= kn-copyright= en-aut-name=KAWAKAMIYoko en-aut-sei=KAWAKAMI en-aut-mei=Yoko kn-aut-name=川上陽子 kn-aut-sei=川上 kn-aut-mei=陽子 aut-affil-num=1 ORCID= affil-num=1 en-affil=Ph.D in law, Université Toulouse Capitole kn-affil= en-keyword=ESD kn-keyword=ESD en-keyword=SDGs kn-keyword=SDGs en-keyword=international environmental law kn-keyword=international environmental law en-keyword=international law kn-keyword=international law en-keyword=human rights kn-keyword=human rights END start-ver=1.4 cd-journal=joma no-vol=4 cd-vols= no-issue= article-no= start-page=19 end-page=52 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Mineralogy and geochemistry of magnetite-garnet bearing skarn deposits surrounding iron-smelting sites in the Kibi region of Japan kn-title=吉備製鉄遺跡周辺地域の磁鉄鉱ざくろ石スカルン鉄鉱石の鉱物学的・地球化学的特徴 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We conducted mineralogical and geochemical analysis of ore samples taken from locations surrounding the Jinmu, Sanpō, and Kōmoto mines in order to determine the source of iron ore uncovered from archaeological sites. The mineral composition of the magnetite-garnet bearing skarn deposits varies from mine to mine: while clinopyroxene and amphibole are present in the Jinmu and Sanpō samples, only a small amount of clinopyroxene occurs in the Kōmoto samples. The chemical compositions of magnetite and garnet are distinctive for each mine. Among the trace elements contained in the magnetite, Mg and Mn tend to be higher in the Kōmoto samples, Ti in the Jinmu samples, and Ca and Si in the Sanpō samples. The garnet from all the mines is andradite, but while the Kōmoto samples contain almost no Al, it is present in the Jinmu and Sanpō samples. Although samples were taken from a limited number of mine areas (three), our analysis provides an index for comparison with iron ore uncovered from archaeological sites, which will aid in provenance determination. en-copyright= kn-copyright= en-aut-name=TAKECHIYasushi en-aut-sei=TAKECHI en-aut-mei=Yasushi kn-aut-name=武智泰史 kn-aut-sei=武智 kn-aut-mei=泰史 aut-affil-num=1 ORCID= en-aut-name=NAKAMURADaisuke en-aut-sei=NAKAMURA en-aut-mei=Daisuke kn-aut-name=中村大輔 kn-aut-sei=中村 kn-aut-mei=大輔 aut-affil-num=2 ORCID= en-aut-name=SUZUKIShigeyuki en-aut-sei=SUZUKI en-aut-mei=Shigeyuki kn-aut-name=鈴木茂之 kn-aut-sei=鈴木 kn-aut-mei=茂之 aut-affil-num=3 ORCID= en-aut-name=RYANJoseph en-aut-sei=RYAN en-aut-mei=Joseph kn-aut-name=ライアンジョセフ kn-aut-sei=ライアン kn-aut-mei=ジョセフ aut-affil-num=4 ORCID= en-aut-name=UWAGAKITakeshi en-aut-sei=UWAGAKI en-aut-mei=Takeshi kn-aut-name=上栫武 kn-aut-sei=上栫 kn-aut-mei=武 aut-affil-num=5 ORCID= en-aut-name=NAGAHARAMasato en-aut-sei=NAGAHARA en-aut-mei=Masato kn-aut-name=長原正人 kn-aut-sei=長原 kn-aut-mei=正人 aut-affil-num=6 ORCID= en-aut-name=YOSHIEYuta en-aut-sei=YOSHIE en-aut-mei=Yuta kn-aut-name=吉江雄太 kn-aut-sei=吉江 kn-aut-mei=雄太 aut-affil-num=7 ORCID= en-aut-name=IKEHATAKei en-aut-sei=IKEHATA en-aut-mei=Kei kn-aut-name=池端慶 kn-aut-sei=池端 kn-aut-mei=慶 aut-affil-num=8 ORCID= en-aut-name=KIMURAOsamu en-aut-sei=KIMURA en-aut-mei=Osamu kn-aut-name=木村理 kn-aut-sei=木村 kn-aut-mei=理 aut-affil-num=9 ORCID= en-aut-name=HATTORIRyoichi en-aut-sei=HATTORI en-aut-mei=Ryoichi kn-aut-name=服部亮一 kn-aut-sei=服部 kn-aut-mei=亮一 aut-affil-num=10 ORCID= affil-num=1 en-affil=Kurashiki Museum of Natural History kn-affil= affil-num=2 en-affil=Okayama University, Department of Earth Sciences kn-affil= affil-num=3 en-affil=Okayama University, Department of Earth Sciences kn-affil= affil-num=4 en-affil=Okayama University, Research Institute for the Dynamics of Civilizations kn-affil= affil-num=5 en-affil=Okayama Prefectural Board of Education kn-affil= affil-num=6 en-affil=The Historical Study Group of Mining and Metallurgy of Japan kn-affil= affil-num=7 en-affil=Mitsui Mining & Smelting Co., Ltd. kn-affil= affil-num=8 en-affil=University of Tsukuba, Faculty of Life and Environmental Sciences kn-affil= affil-num=9 en-affil=Okayama University, Research Institute for the Dynamics of Civilizations kn-affil= affil-num=10 en-affil=Osaka University, Graduate School of Humanities kn-affil= en-keyword=Iron-smithing sites kn-keyword=Iron-smithing sites en-keyword=skarn deposits kn-keyword=skarn deposits en-keyword=mineral composition of ore kn-keyword=mineral composition of ore en-keyword=geochemical analysis kn-keyword=geochemical analysis END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241207 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Optimization of workflow processes for sustainable paternal involvement: case study of an academic “daddy surgeon” in Japan en-subtitle= kn-subtitle= en-abstract= kn-abstract=Work–life balance is often discussed in Japan. Yet surgeons find it challenging to take paternity leave because of their demanding surgical duties and a strong sense of responsibility. One Japanese male surgeon had his first paternity experience as a research fellow in the US. When he returned to Japan, he resumed his surgical training and started a research project to become an academic surgeon. When he and his wife were expecting their second child, they discussed his paternity participation before the delivery and decided on a sustainable paternity participation plan. By coordinating his responsibilities with his co-workers, he limited his attendance at work to daytime hours only for 1 month to manage paternity duties. This adjustment did not affect the number of main and assistant operations conducted that month and effective optimization of workflow processes decreased the extra workload for other team members. His experience suggests that the optimization of workflow processes can enhance personal life, including paternity participation. (150/150). en-copyright= kn-copyright= en-aut-name=KanayaNobuhiko en-aut-sei=Kanaya en-aut-mei=Nobuhiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KurodaShinji en-aut-sei=Kuroda en-aut-mei=Shinji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KondoYoshitaka en-aut-sei=Kondo en-aut-mei=Yoshitaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TakeharaYuko en-aut-sei=Takehara en-aut-mei=Yuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KakiuchiYoshihiko en-aut-sei=Kakiuchi en-aut-mei=Yoshihiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MinagiHitoshi en-aut-sei=Minagi en-aut-mei=Hitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SakamotoMasaki en-aut-sei=Sakamoto en-aut-mei=Masaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KagawaShunsuke en-aut-sei=Kagawa en-aut-mei=Shunsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KataokaHitomi en-aut-sei=Kataoka en-aut-mei=Hitomi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= affil-num=2 en-affil=Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= affil-num=3 en-affil=Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= affil-num=4 en-affil=Department of Surgery, Okayama Saiseikai General Hospital kn-affil= affil-num=5 en-affil=Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= affil-num=6 en-affil=Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= affil-num=7 en-affil=Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= affil-num=8 en-affil=Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= affil-num=9 en-affil=Integrated Clinical Education Center, Kyoto University Hospital kn-affil= affil-num=10 en-affil=Department of Gastroenterological Surgery, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= en-keyword=Optimization of workflow processes kn-keyword=Optimization of workflow processes en-keyword=Sustainable paternity participation kn-keyword=Sustainable paternity participation en-keyword=“Daddy surgeon” kn-keyword=“Daddy surgeon” END start-ver=1.4 cd-journal=joma no-vol=33 cd-vols= no-issue=4 article-no= start-page=213 end-page=218 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=2024 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=β-catenin Binds to Gsk-3β in Liquid-Liquid Phase Separation Compartment in HEK293 Cells en-subtitle= kn-subtitle= en-abstract= kn-abstract=Liquid-liquid phase separation (LLPS) has emerged as a significant mechanism for cellular organization, impacting various biological processes, including Wnt/β-catenin signaling. This study investigates the role of LLPS in the regulation of β-catenin in HEK293 cells, particularly in response to Wnt3a signaling. Our findings demonstrate that β-catenin is regulated by LLPS, forming spherical droplets indicative of this phenomenon. Fluorescence recovery after photobleaching (FRAP) assays revealed that these droplets exhibit reversible dynamics, further confirming their phase-separated nature. Importantly, treatment with Wnt3a led to an increase in β-catenin levels, while simultaneously reducing the recovery of fluorescence intensity in FRAP experiments, suggesting that enhanced Wnt signaling may stimulate the release of β-catenin from LLPS. Immunoprecipitation studies indicated that β-catenin binds to glycogen synthase kinase 3β (Gsk-3β) within the LLPS state, highlighting a potential regulatory mechanism whereby LLPS facilitates the phosphorylation and subsequent degradation of β-catenin. The addition of 1,6-hexanediol disrupted the β-catenin/Gsk-3β interaction, reinforcing the idea that LLPS plays a critical role in modulating these biochemical interactions. The findings presented in this study suggest that LLPS is not only crucial for the spatial organization of β-catenin but also serves as a regulatory mechanism for its signaling functions in the Wnt pathway. Given the association of aberrant Wnt signaling with various diseases, including cancer and neurodegenerative disorders, understanding the role of LLPS in this context may provide new insights into therapeutic strategies targeting these pathological conditions. en-copyright= kn-copyright= en-aut-name=KatoMari en-aut-sei=Kato en-aut-mei=Mari kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TanaiAiri en-aut-sei=Tanai en-aut-mei=Airi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FukuharaYoko en-aut-sei=Fukuhara en-aut-mei=Yoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ZhengXinyu en-aut-sei=Zheng en-aut-mei=Xinyu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SitosariHeriati en-aut-sei=Sitosari en-aut-mei=Heriati kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=YamamotoTadashi en-aut-sei=Yamamoto en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=IkegameMika en-aut-sei=Ikegame en-aut-mei=Mika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=OkamuraHirohiko en-aut-sei=Okamura en-aut-mei=Hirohiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=6 en-affil=The Center for Graduate Medical Education (Dental Division), Okayama University Hospital kn-affil= affil-num=7 en-affil=Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=8 en-affil=Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=β-catenin kn-keyword=β-catenin en-keyword=Gsk-3β kn-keyword=Gsk-3β en-keyword=LLPS kn-keyword=LLPS en-keyword=Wnt kn-keyword=Wnt END start-ver=1.4 cd-journal=joma no-vol=26 cd-vols= no-issue=51 article-no= start-page=11111 end-page=11116 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241216 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Electrogenerated Lewis Acid-Catalyzed Claisen Rearrangement of Allyl Aryl Ethers en-subtitle= kn-subtitle= en-abstract= kn-abstract=Catalysts for Claisen rearrangement have been intensively studied to overcome the need for high temperature. However, previous studies have encountered challenges, such as the need for heating, a long reaction time, and/or the need for equivalent amounts of catalyst. In this study, we introduce an effective electrogenerated boron-based Lewis acid catalyst for the aromatic Claisen rearrangement, which proceeds in a few minutes at ambient temperature. Generation of the electrogenerated Lewis acid catalyst is discussed based on NMR analysis and DFT calculations. en-copyright= kn-copyright= en-aut-name=NikiYuta en-aut-sei=Niki en-aut-mei=Yuta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MitsudoKoichi en-aut-sei=Mitsudo en-aut-mei=Koichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SatoEisuke en-aut-sei=Sato en-aut-mei=Eisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SugaSeiji en-aut-sei=Suga en-aut-mei=Seiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=74 cd-vols= no-issue=2 article-no= start-page=158 end-page=109 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241220 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Die Übersetzung von Jherings Briefe（8） kn-title=イェーリング書簡集⑻（ギーセン時代：1852－68年③） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HirataK. en-aut-sei=Hirata en-aut-mei=K. kn-aut-name=平田公夫 kn-aut-sei=平田 kn-aut-mei=公夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学名誉教授 END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=裏表紙・英文目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=奥付 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=145 end-page=151 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=What Is “Meaning” ? kn-title=意味づけするとは何か en-subtitle= kn-subtitle= en-abstract= kn-abstract=　人間はコミュニケーションの動物であると言われる。しかしその対象についての解釈（意味）が異なればコミュニケーションは成立しない。本論では意味づけするとはどういうことなのかについて考える。 en-copyright= kn-copyright= en-aut-name=MIYAZAKIHiroshi en-aut-sei=MIYAZAKI en-aut-mei=Hiroshi kn-aut-name=宮﨑宏志 kn-aut-sei=宮﨑 kn-aut-mei=宏志 aut-affil-num=1 ORCID= en-aut-name=SOBUKAWATakuya en-aut-sei=SOBUKAWA en-aut-mei=Takuya kn-aut-name=曽布川拓也 kn-aut-sei=曽布川 kn-aut-mei=拓也 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Global Education Center, Waseda University kn-affil=早稲田大学グローバルエデュケーションセンター en-keyword=素象 kn-keyword=素象 en-keyword=コミュニケーション kn-keyword=コミュニケーション en-keyword=意味づけ kn-keyword=意味づけ END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=129 end-page=143 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Comprehensive Curriculum Management Consulting Design for Kindergartens, Nursery Schools, and Certified Centers for Contemporary Early Childhood Care and Education in Japan kn-title=幼稚園・保育所・認定こども園のためのカリキュラム・マネジメント・コンサルティングの全体構想 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究では，幼稚園・保育所・認定こども園に所属する保育者の研修に関する先行研究を概観した上で，現在必要とされる研修のあり方として，カリキュラム・マネジメント・コンサルティングを提示し，その全体構想を示している。まず，カリキュラム・マネジメント・コンサルティングの意味内容を明確にすると共に，それが必要とされる理由について論じている。次に，カリキュラム・マネジメント・コンサルティングを実現可能にしている思考の仕方と実務内容の全体像と保育者の成長及び保育施設の発展についての展望を示している。その上で，私立の幼稚園・保育所・認定こども園と公立の幼稚園・保育所・認定こども園とでは経営環境が異なることを踏まえて，それぞれのためのカリキュラム・マネジメント・コンサルティングを行う際の留意点について考察している。 en-copyright= kn-copyright= en-aut-name=YOKOMATSUTomoyoshi en-aut-sei=YOKOMATSU en-aut-mei=Tomoyoshi kn-aut-name=横松友義 kn-aut-sei=横松 kn-aut-mei=友義 aut-affil-num=1 ORCID= en-aut-name=MORIHideko en-aut-sei=MORI en-aut-mei=Hideko kn-aut-name=森英子 kn-aut-sei=森 kn-aut-mei=英子 aut-affil-num=2 ORCID= en-aut-name=MAEDANobumi en-aut-sei=MAEDA en-aut-mei=Nobumi kn-aut-name=前田信美 kn-aut-sei=前田 kn-aut-mei=信美 aut-affil-num=3 ORCID= en-aut-name=KONYARyotaro en-aut-sei=KONYA en-aut-mei=Ryotaro kn-aut-name=紺谷遼太郎 kn-aut-sei=紺谷 kn-aut-mei=遼太郎 aut-affil-num=4 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Department of Child Development, Sanyo Gakuen College kn-affil=山陽学園短期大学こども育成学科 affil-num=3 en-affil=Department of Child Development, Sanyo Gakuen College kn-affil=山陽学園短期大学こども育成学科 affil-num=4 en-affil=Department of Music, Sakuyo Junior College kn-affil=作陽短期大学音楽学科 en-keyword=幼稚園 kn-keyword=幼稚園 en-keyword=保育所 kn-keyword=保育所 en-keyword=認定こども園 kn-keyword=認定こども園 en-keyword=カリキュラム・マネジメント・コンサルティング kn-keyword=カリキュラム・マネジメント・コンサルティング END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=119 end-page=127 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Analysis of The Curriculum Guidelines on Cleaning Instruction for Students with Intellectual Disabilities kn-title=知的障害のある児童生徒への掃除指導に関する学習指導要領の分析 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿では，知的障害のある児童生徒への掃除指導について，学習指導要領および学習指導要領解説に記載された内容の分析を通して，知的障害のある児童生徒への掃除指導で踏まえるべき内容を明らかにし，学校現場でその内容を教える上での課題を考察した。結果，各教科において，掃除を行う資質・能力の獲得をねらった指導が小学部段階から高等部段階にかけて系統的に位置づけられていること，道徳科や特別活動において，勤労観や責任感などの精神面の醸成に掃除指導が活用されていること，そして，異年齢集団との関わりの促進に掃除指導の場面が期待されていることが分かった。今後の課題として，学習指導要領および学習指導要領解説で示された掃除に関する資質・能力を具体化すること，掃除指導による精神面の醸成や異年齢集団との関わりの促進に重点をおいた研究を行うことが示唆された。 en-copyright= kn-copyright= en-aut-name=MATSUSHITAYoshimasa en-aut-sei=MATSUSHITA en-aut-mei=Yoshimasa kn-aut-name=松下泰将 kn-aut-sei=松下 kn-aut-mei=泰将 aut-affil-num=1 ORCID= en-aut-name=OHTAKEYoshihisa en-aut-sei=OHTAKE en-aut-mei=Yoshihisa kn-aut-name=大竹喜久 kn-aut-sei=大竹 kn-aut-mei=喜久 aut-affil-num=2 ORCID= affil-num=1 en-affil=The Joint Graduate School in Science of School Education (Doctor’s Course), Hyogo University of Teacher Education kn-affil=兵庫教育大学大学院連合学校教育学研究科（博士課程） affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=知的障害 kn-keyword=知的障害 en-keyword=掃除指導 kn-keyword=掃除指導 en-keyword=学習指導要領 kn-keyword=学習指導要領 END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=111 end-page=118 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Junior High School Students' Understanding of Truss Structures in Classroom Practice Using VR Structural Mechanics Teaching Materials kn-title=VR 構造力学教材を用いた授業実践から見える中学生のトラス構造理解 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　中学校技術・家庭科［技術分野］においてプラスチックストロー等の材料で橋を製作させる試みが行われている。橋の強度を確保するための基本はトラス構造であるが，各部材（プラスチックストロー等）に生じる力の大きさとその方向を正確に理解することは生徒にとって難しい。著者はトラス構造を学習するVR構造力学教材を開発し，ストロー橋製作の助けとなる授業実践を行ってきた。この授業実践の中で，生徒がトラス構造の各部材に生じる力を考察するときの誤りのパターンが明らかになった。本研究ではこれまでの授業実践でよく見られた誤り方を生徒に提示し，同じ誤り方をしたかどうか，なぜそのように考えたのかについて調査した上で，求められる指導方法について検討した。 en-copyright= kn-copyright= en-aut-name=IRIETakashi en-aut-sei=IRIE en-aut-mei=Takashi kn-aut-name=入江隆 kn-aut-sei=入江 kn-aut-mei=隆 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=技術分野 kn-keyword=技術分野 en-keyword=構造力学 kn-keyword=構造力学 en-keyword=トラス構造 kn-keyword=トラス構造 en-keyword=VR kn-keyword=VR en-keyword=教材 kn-keyword=教材 END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=101 end-page=110 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Research on Deepening Views of Subjects in Home Economics Training Courses: Incorporate Opportunities to Compare Home Economics and Other Subjects kn-title=家庭科教員養成課程における教科観の深化に関する研究 ― 家庭科と他教科を比較する機会の導入 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿では，森・鈴木（2017，2021），詫間・鈴木（2023）で検証した家庭科教員志望の大学生や大学院生の教科観の深化を促す方法を整理するとともに，各方法を取り入れる適切な時期を検討し，家庭科教員養成課程への導入方法を提案することを目的とした。
　家庭科と他教科を比較する方法には，各教科の共通点や相違点を整理させる【方法①】，各教科の既存の授業案を検討する【方法②】，共通テーマを設定した各教科の授業案を作成する【方法③】の三つがあり，取り入れる時期（学年）によって効果に差が出ると考えられた。そのため，教育実習前までの段階では【方法①】を，教育実習後は【方法①】と【方法②】を，大学院生時には【方法①】と【方法③】を組み合わせる等，学部から修士課程までの導入方法を提案した。 en-copyright= kn-copyright= en-aut-name=TAKUMAChiharu en-aut-sei=TAKUMA en-aut-mei=Chiharu kn-aut-name=詫間千晴 kn-aut-sei=詫間 kn-aut-mei=千晴 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=家庭科教員養成課程 kn-keyword=家庭科教員養成課程 en-keyword=教科観 kn-keyword=教科観 en-keyword=家庭科 kn-keyword=家庭科 en-keyword=他教科 kn-keyword=他教科 END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=77 end-page=99 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Research on ICT-Based Class Development for “Proactive, Interactive, and Authentic Learning” in “Home Economics” at Senior High School ( Ⅱ ): Developing and Implementing a Lesson on “Why Do We Need to Plan Meals for a Lifetime?” kn-title=高等学校「家庭」における主体的・対話的で深い学びを目指す ICT を活用した授業開発（Ⅱ） ―「 なぜ，生涯を見通した食事計画を立てる必要があるのか」の開発と実践 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本継続研究では，2016年の知識基盤社会を生きる力の育成を目的とした教育改革において，「社会に開かれた教育課程」の実現のために，授業改善の課題とされた「主体的・対話的で深い学びの実現」と「適切なICT活用による学習活動の充実」に焦点を当て，高等学校普通科目の家庭科において，「主体的・対話的で深い学び」とそれにつながるICT活用の検討による授業開発研究を行い，「主体的・対話的で深い学び」を成立させる授業構成の条件を検討することを目的とした。本稿では，家庭科の「深い学び」に不可欠な「自分と食事計画との関係」を探究する授業「なぜ，生涯を見通した食事計画を立てる必要があるのか」の開発と実践結果を中心に報告する。 en-copyright= kn-copyright= en-aut-name=SATOSono en-aut-sei=SATO en-aut-mei=Sono kn-aut-name=佐藤園 kn-aut-sei=佐藤 kn-aut-mei=園 aut-affil-num=1 ORCID= en-aut-name=HASEGAWAChika en-aut-sei=HASEGAWA en-aut-mei=Chika kn-aut-name=長谷川千華 kn-aut-sei=長谷川 kn-aut-mei=千華 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Okayama Mitsu Senior High School kn-affil=岡山県立岡山御津高等学校 en-keyword=家庭科 kn-keyword=家庭科 en-keyword=主体的・対話的で深い学び kn-keyword=主体的・対話的で深い学び en-keyword=ICT kn-keyword=ICT en-keyword=食生活学習 kn-keyword=食生活学習 en-keyword=高等学校 kn-keyword=高等学校 END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=69 end-page=76 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Basic Research on the Appreciation of Sculpture Works by Children in Schools for the Blind -Through the arrangement of issues based on the literature survey- kn-title=盲学校の児童の彫刻作品鑑賞に関する基礎研究 ― 文献調査による課題整理を通して ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究は，日本美術教育学会の兵庫支部を中心として進められている「福来四郎アートプロジェクト」（以下，FAPと表記）に関するものである。本論では，彫刻の鑑賞に関する先行研究を調査することで，彫刻の鑑賞学習における現状の課題を整理し，FAPに関する研究に期待できることを整理する。本調査では，先行研究の調査期間を2008年から2023年の16年間と設定し，美術教育に関する学会誌の三誌に掲載されている研究論文を対象とした。その結果，本調査から彫刻の鑑賞学習における課題として①視覚情報を前提とした彫刻の鑑賞学習が先行していること，②生涯教育として彫刻の鑑賞学習を捉えにくいことを確認できた。以上の結果から，FAPの研究には，触覚に基づく鑑賞学習としての有用性や，生涯教育の視点からの鑑賞学習の可能性が期待できることを分かった。 en-copyright= kn-copyright= en-aut-name=MATSUURAAi en-aut-sei=MATSUURA en-aut-mei=Ai kn-aut-name=松浦藍 kn-aut-sei=松浦 kn-aut-mei=藍 aut-affil-num=1 ORCID= en-aut-name=FujitaMasaya en-aut-sei=Fujita en-aut-mei=Masaya kn-aut-name=藤田雅也 kn-aut-sei=藤田 kn-aut-mei=雅也 aut-affil-num=2 ORCID= en-aut-name=KIYOTATetsuo en-aut-sei=KIYOTA en-aut-mei=Tetsuo kn-aut-name=清田哲男 kn-aut-sei=清田 kn-aut-mei=哲男 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Department of Children’s Studies, Junior College of Shizuoka Prefectural University kn-affil=静岡県立大学短期大学部こども学科 affil-num=3 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=美術教育 kn-keyword=美術教育 en-keyword=彫刻 kn-keyword=彫刻 en-keyword=鑑賞 kn-keyword=鑑賞 en-keyword=触覚 kn-keyword=触覚 en-keyword=視覚 kn-keyword=視覚 END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=53 end-page=67 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Comparison of Acoustic Characteristics of Performances Conducted in Different Ways and Examination of Impression Investigations of the Performances kn-title=指揮状況の違いによる音響特性の比較と演奏の印象調査の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　筆者等は，音楽授業での指揮状況を向上させる方策として，授業での教員の立ち位置と指揮の仕方に注目した。異なる立ち位置と異なる指揮の仕方で演奏した場合，各々の演奏が音響学的にどのように変化するのか音カメラ装置で測定した。併せて，各々の演奏に対して受講学生の印象調査を行った。音響特性から，指揮の仕方によって，音節が明瞭になること（スペクトログラムの濃さ），ビブラートに変化が見られること（「ゆれ」の表れ），音量が変化すること（音圧レベル），音価が異なってくること（時間軸波形）が示された。印象調査からは，指揮者が，ピアノの位置で指揮をするのに比べて，合唱者の前で指揮をすることで，アゴーギク，ディナーミック，表現の豊かさに対する演奏の評価が大きく反転した。指揮の仕方では，形式的な指揮に比べて，音楽的な要素を入れた指揮をすると，アゴーギク，ディナーミック，息の流れの演奏評価が高くなった。さらに，音響特性と音楽表現との関連性が視覚的に確認され，特に，「ゆれ」（ビブラート）の頻出は，音楽表現を豊かにすることが示された。 en-copyright= kn-copyright= en-aut-name=MUSHIAKIMasako en-aut-sei=MUSHIAKI en-aut-mei=Masako kn-aut-name=虫明眞砂子 kn-aut-sei=虫明 kn-aut-mei=眞砂子 aut-affil-num=1 ORCID= en-aut-name=ZAIMATakefumi en-aut-sei=ZAIMA en-aut-mei=Takefumi kn-aut-name=財満健史 kn-aut-sei=財満 kn-aut-mei=健史 aut-affil-num=2 ORCID= en-aut-name=OWAKIMasanao en-aut-sei=OWAKI en-aut-mei=Masanao kn-aut-name=大脇雅直 kn-aut-sei=大脇 kn-aut-mei=雅直 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学名誉教授 affil-num=2 en-affil=Technical Research &Development Institute, Kumagaigumi Co., Ltd. kn-affil=株式会社熊谷組　技術本部　技術研究所　環境工学研究室 affil-num=3 en-affil=Technical Research &Development Division, Kumagaigumi Co., Ltd. kn-affil=株式会社熊谷組　技術本部 en-keyword=指揮 kn-keyword=指揮 en-keyword=音響特性 kn-keyword=音響特性 en-keyword=印象調査 kn-keyword=印象調査 en-keyword=比較 kn-keyword=比較 en-keyword=演奏 kn-keyword=演奏 END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=43 end-page=51 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Piano Distance Education Using ICT in the Present Context-Piano Teaching Using Yamaha Disklavier at the Freiburg University of Music- kn-title=ICT を用いたピアノの遠隔教育の現状 ― フライブルク音楽大学におけるヤマハ・ディスクラビアを活用したピアノ指導 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　筆者は2023年４月，世界初のリモート入試で注目されたフライブルク音楽大学を訪問し，ヤマハ・ディスクラビアがもつリモート機能を活用した遠隔レッスンについて調査を行った。その結果，MIDIに記録された楽器の動作データを使用した「疑似アンサンブル」や「演奏の可視化」など，単にリモート機能の活用に留まらないICTをフルに活用したピアノの指導事例を見ることができた。特にMIDIデータの活用は，ICTが今後のピアノ指導の在り方に，大きな影響を与えていく可能性を秘めた事例であった。 en-copyright= kn-copyright= en-aut-name=NAGAOKAIsao en-aut-sei=NAGAOKA en-aut-mei=Isao kn-aut-name=長岡功 kn-aut-sei=長岡 kn-aut-mei=功 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=ディスクラビア kn-keyword=ディスクラビア en-keyword=ICT kn-keyword=ICT en-keyword=ピアノ指導 kn-keyword=ピアノ指導 en-keyword=可視化 kn-keyword=可視化 en-keyword=遠隔レッスン kn-keyword=遠隔レッスン END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=35 end-page=42 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Formative Activity that Creates Social Groups through Antagonism and Articulation kn-title=敵対性と節合により社会を創造する芸術実践の文献研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　This study, using literature, explores the theory of socially engaged art, along with formative activities that feature elements of socially engaged art that contribute to the realization of an educational curriculum that is open to society. This study clarified the effects of the formative activities. Therefore, the theory of socially engaged art encompasses antagonism, an experience that changes how one views, feels, and thinks about children and others, and articulation, which creates or reshapes the relationship between children and others. A literature survey revealed that emotional experiences that change the way children and others see, feel, and think can lead to a reshaping of existing relationships between children and others, as well as the formation of new relationships between children and others. This study demonstrated the effects of formative activity creating social aspects by doing things. en-copyright= kn-copyright= en-aut-name=OHIRAShuya en-aut-sei=OHIRA en-aut-mei=Shuya kn-aut-name=大平修也 kn-aut-sei=大平 kn-aut-mei=修也 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=Socially engaged art kn-keyword=Socially engaged art en-keyword=Antagonism kn-keyword=Antagonism en-keyword=Articulation kn-keyword=Articulation en-keyword=Social kn-keyword=Social en-keyword=Formative activity kn-keyword=Formative activity END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=23 end-page=33 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Issues Observed in Students Who Want to Become Childcare Workers regarding Earthquake Response during Childcare kn-title=保育者志望学生に見る保育時の地震発生対応に関する課題 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　保育者養成校での地震防災に関する授業や指導内容の再検討に示唆を得るため，保育者志望学生に見る保育現場で地震が発生した際の対応に関する不安と，保育職に就く前に学んでおきたい内容について検証した。その結果，保育時に地震が発生した際の対応に関して，①子どもを落ち着かせるための対応，②自分の冷静な行動や判断，③安全な避難や誘導，に不安を感じていることが確認できた。また，保育職に就く前に，①安全な避難の仕方や子どもを守るための方法，②子どもを落ち着かせるための方法や対応，③地震や地震防災の知識，を学びたいと考えていることが分かった。学びたい内容と学ばせたい内容をすり合わせ，確かな防災力の習得と実践力を培う授業内容の検討が今後の課題である。 en-copyright= kn-copyright= en-aut-name=BABANoriko en-aut-sei=BABA en-aut-mei=Noriko kn-aut-name=馬場訓子 kn-aut-sei=馬場 kn-aut-mei=訓子 aut-affil-num=1 ORCID= en-aut-name=SATOHDaisuke en-aut-sei=SATOH en-aut-mei=Daisuke kn-aut-name=佐藤大介 kn-aut-sei=佐藤 kn-aut-mei=大介 aut-affil-num=2 ORCID= en-aut-name=TAKAHASHIKei en-aut-sei=TAKAHASHI en-aut-mei=Kei kn-aut-name=髙橋慧 kn-aut-sei=髙橋 kn-aut-mei=慧 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Kawasaki University of Medical Welfare kn-affil=川崎医療福祉大学 affil-num=3 en-affil=Kurashiki Sakuyo University kn-affil=くらしき作陽大学 en-keyword=保育者志望学生 kn-keyword=保育者志望学生 en-keyword=保育時 kn-keyword=保育時 en-keyword=地震 kn-keyword=地震 en-keyword=課題 kn-keyword=課題 en-keyword=質問紙調査 kn-keyword=質問紙調査 END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=11 end-page=21 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Factors Shaping Followership Behavior in University Students: The Role of Club Activities in Fostering “the Ability to Contribute to the Organization” ? kn-title=大学生のフォロワーシップ行動とその形成要因 ― 部活動・サークルで培われる “組織へ貢献する力” ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究では，大学の部活動・サークルを “組織へ貢献する力” が培われる場と位置づけ，大学生のフォロワーシップ行動とその形成要因について実証的に検討した。フォロワーシップの形成に寄与する個人要因として部活動・サークルへのコミットメント，組織環境要因としてチームリーダーシップと集団フォーマル性に着目し，大学生を対象に質問紙調査を行った。125名の有効回答に対して，パス解析を行った結果，チームリーダーシップの「建設的な後押し」と集団フォーマル性が，「集団同一視コミットメント」を向上し，それが３種のフォロワーシップ行動（（「批判的行動」，「積極的行動」，「配慮的行動」）を促進するという影響過程が示唆された。 en-copyright= kn-copyright= en-aut-name=MISAWARyo en-aut-sei=MISAWA en-aut-mei=Ryo kn-aut-name=三沢良 kn-aut-sei=三沢 kn-aut-mei=良 aut-affil-num=1 ORCID= en-aut-name=IWASHITAMisaki en-aut-sei=IWASHITA en-aut-mei=Misaki kn-aut-name=岩下美咲 kn-aut-sei=岩下 kn-aut-mei=美咲 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=CAREER PLANNING Co., Ltd. kn-affil=株式会社キャリアプランニング en-keyword=フォロワーシップ kn-keyword=フォロワーシップ en-keyword=チームリーダーシップ kn-keyword=チームリーダーシップ en-keyword=集団フォーマル性 kn-keyword=集団フォーマル性 en-keyword=コミットメント kn-keyword=コミットメント END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page=1 end-page=10 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Changing of Study and Training of Teachers in the Modern China: Its Process and Issues kn-title=現代中国における現職教員研修の展開 ― その過程と課題に関する一考察 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　中華人民共和国が成立し，中国政府は国民教育を担う教員の養成と研修（在職学習）に対する関心を強めた。初等中等教育の教員研修に関する政策を順次実施し，現職教員の量と質を管理しようとした。政府の教員研修への積極的関与は，教員の学びを分散から体系化へ，無秩序から標準化へと導く過程であった。その政策的展開を緊急需要期（1949-1984 年），模索・標準化期（1985-1999 年），発展・形成期（2000-2010 年），改善・確立期（2011-現在）という４つの時期整理にもとづいて考察する。そして，政府の強力指導と近年の情報技術活用による教員研修の推進は，全国的な教員研修の水準を形成したが，課題として，地域差，教員個々の経験や意欲の多様性などに対する取組の必要を気づかせるものであったことを指摘する。教員政策における標準化と多元化のせめぎあいが，現代中国の教員研修事情から看取される。 en-copyright= kn-copyright= en-aut-name=KAJIIKazuaki en-aut-sei=KAJII en-aut-mei=Kazuaki kn-aut-name=梶井一暁 kn-aut-sei=梶井 kn-aut-mei=一暁 aut-affil-num=1 ORCID= en-aut-name=SUNYingju en-aut-sei=SUN en-aut-mei=Yingju kn-aut-name=孫瑛鞠 kn-aut-sei=孫 kn-aut-mei=瑛鞠 aut-affil-num=2 ORCID= en-aut-name=SUNChangliang en-aut-sei=SUN en-aut-mei=Changliang kn-aut-name=孫長亮 kn-aut-sei=孫 kn-aut-mei=長亮 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Nanjing University of Information Science & Technology kn-affil=南京信息工程大学 affil-num=3 en-affil=Nantong University kn-affil=南通大学 en-keyword=中国 kn-keyword=中国 en-keyword=教員研修 kn-keyword=教員研修 en-keyword=初等中等教育 kn-keyword=初等中等教育 en-keyword=国培計画 kn-keyword=国培計画 en-keyword=培訓指南 kn-keyword=培訓指南 en-keyword=評定 kn-keyword=評定 END start-ver=1.4 cd-journal=joma no-vol=187 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=表紙・目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue= article-no= start-page=1434800 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241127 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Efficacy of extracting and preventively intervening late-stage older adults who are at high risk for spending high medical costs by using the health check-up system in Japan: a pilot study en-subtitle= kn-subtitle= en-abstract= kn-abstract=Objectives: In Japan, the seven diseases (femur fracture, cerebral infarction, chronic renal failure, heart failure, dementia, pneumonia, and chronic obstructive pulmonary disease) are the top causes of inpatient medical costs among the late-stage older adults aged 75 years and over. This pilot study was conducted with the following two objectives; (1) to examine the proportion of risks of onset and severity of seven diseases among the late-stage older adults, and (2) to examine the efficacy of interventions focusing on the prevention of unplanned hospitalization.
Methods: Participants were 45,233 older adults aged 75 and over living in Kure City, Japan. In addition to the government-mandated health checkup items, the Intervention group underwent additional risk screening tests included questionnaires, physical examinations, blood tests, and educational guidance by nurses. The efficacy of the intervention was examined whether there were differences in the number of hospitalizations, the use of emergency and critical care, and the incidence of hemodialysis induction between the Intervention and control groups (Usual Health Checkup group and No Health Checkup group) for the 2 years.
Results: There were 485 participants in the Intervention group, 1,067 in the Usual Health Checkup group, and 43,712 in the No Health Checkup group. As the risks of seven diseases in the Intervention group, the largest proportion of deviations occurred for systolic blood pressure (63.3%), estimated salt intake (60.3%), and low-density lipoprotein cholesterol (51.5%). Estimated glomerular filtration rate deviated in 41.0%, N-terminal pro b-type natriuretic peptide in 37.9%. 7.5% scored <2 points on the Mini-Cog (c), and 9.1% performed the Timed Up and Go test in >12 s. The incidence of hospitalization due to any of the seven diseases was significantly higher in the No Health Checkup group (p < 0.001). There were no differences among the three groups in the use of emergency and critical care or the introduction of hemodialysis.
Conclusion: This study revealed that additional health checkup tests and intervention methods could be prevented hospitalization among the adults of 75 years and older. It is necessary to make health checkups and follow-ups more accessible those are already available within the existing health system in Japan. en-copyright= kn-copyright= en-aut-name=KazawaKana en-aut-sei=Kazawa en-aut-mei=Kana kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KawaiMadoka en-aut-sei=Kawai en-aut-mei=Madoka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MoriyamaMichiko en-aut-sei=Moriyama en-aut-mei=Michiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Health Sciences, Okayama University kn-affil= affil-num=2 en-affil=Division of Nursing Science, Graduate School of Biomedical and Health Sciences, Hiroshima University kn-affil= affil-num=3 en-affil=Division of Nursing Science, Graduate School of Biomedical and Health Sciences, Hiroshima University kn-affil= en-keyword=older adults kn-keyword=older adults en-keyword=health checkups kn-keyword=health checkups en-keyword=health risk kn-keyword=health risk en-keyword=hospitalization kn-keyword=hospitalization en-keyword=education kn-keyword=education END start-ver=1.4 cd-journal=joma no-vol=32 cd-vols= no-issue=2 article-no= start-page=292 end-page=305 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241128 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The role of C1orf50 in breast cancer progression and prognosis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Although the prognosis of breast cancer has significantly improved compared to other types of cancer, there are still some patients who expire due to recurrence or metastasis. Therefore, it is necessary to develop a method to identify patients with poor prognosis at the early stages of cancer. In the process of discovering new prognostic markers from genes of unknown function, we found that the expression of C1orf50 determines the prognosis of breast cancer patients, especially for those with Luminal A breast cancer. This study aims to elucidate the molecular role of C1orf50 in breast cancer progression. Bioinformatic analyses of the breast cancer dataset of TCGA, and in vitro analyses, reveal the molecular pathways influenced by C1orf50 expression. C1orf50 knockdown suppressed the cell cycle of breast cancer cells and weakened their ability to maintain the undifferentiated state and self-renewal capacity. Interestingly, upregulation of C1orf50 increased sensitivity to CDK4/6 inhibition. In addition, C1orf50 was found to be more abundant in breast cancer cells than in normal breast epithelium, suggesting C1orf50’s involvement in breast cancer pathogenesis. Furthermore, the mRNA expression level of C1orf50 was positively correlated with the expression of PD-L1 and its related factors. These results suggest that C1orf50 promotes breast cancer progression through cell cycle upregulation, maintenance of cancer stemness, and immune evasion mechanisms. Our study uncovers the biological functions of C1orf50 in Luminal breast cancer progression, a finding not previously reported in any type of cancer. en-copyright= kn-copyright= en-aut-name=OtaniYusuke en-aut-sei=Otani en-aut-mei=Yusuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TanakaAtsushi en-aut-sei=Tanaka en-aut-mei=Atsushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MaekawaMasaki en-aut-sei=Maekawa en-aut-mei=Masaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=PeñaTirso en-aut-sei=Peña en-aut-mei=Tirso kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=RogachevskayaAnna en-aut-sei=Rogachevskaya en-aut-mei=Anna kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=AndoTeruhiko en-aut-sei=Ando en-aut-mei=Teruhiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ItanoTakuto en-aut-sei=Itano en-aut-mei=Takuto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KatayamaHaruyoshi en-aut-sei=Katayama en-aut-mei=Haruyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=NakataEiji en-aut-sei=Nakata en-aut-mei=Eiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=OzakiToshifumi en-aut-sei=Ozaki en-aut-mei=Toshifumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=ToyookaShinichi en-aut-sei=Toyooka en-aut-mei=Shinichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=DoiharaHiroyoshi en-aut-sei=Doihara en-aut-mei=Hiroyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=RoehrlMichael H. en-aut-sei=Roehrl en-aut-mei=Michael H. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=FujimuraAtsushi en-aut-sei=Fujimura en-aut-mei=Atsushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= affil-num=1 en-affil=Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA Harvard Medical School kn-affil= affil-num=2 en-affil=Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA Harvard Medical School kn-affil= affil-num=3 en-affil=Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA Harvard Medical School kn-affil= affil-num=4 en-affil=Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA Harvard Medical School kn-affil= affil-num=5 en-affil=Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA Harvard Medical School kn-affil= affil-num=6 en-affil=Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil=Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=10 en-affil=Department of Orthopedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=11 en-affil=Department of General Thoracic Surgery and Breast and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=12 en-affil=Department of General Surgery, Kawasaki Medical School General Medical Center kn-affil= affil-num=13 en-affil=Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA Harvard Medical School kn-affil= affil-num=14 en-affil=Department of Cellular Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=C1orf50 kn-keyword=C1orf50 en-keyword=Luminal A breast cancer kn-keyword=Luminal A breast cancer en-keyword=Cell cycle kn-keyword=Cell cycle en-keyword=Immune evasion kn-keyword=Immune evasion en-keyword=YAP/TAZ kn-keyword=YAP/TAZ END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue= article-no= start-page=1445364 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241031 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Degree of twist in the Achilles tendon interacts with its length and thickness in affecting local strain magnitude: a finite element analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Introduction: The relationship between the twisting of the three subtendons of the Achilles tendon (AT) and local strain has received attention in recent years. The present study aimed to elucidate how the degree of twist in the AT affects strain using finite element (FE) analysis, while also considering other geometries (e.g., length, thickness, and width) and their combinations.
Methods: A total of 59 FE models with different degrees of twist and geometries were created. A lengthening force (z-axis) of 1,000 N was applied to each subtendon (total: 3,000 N). The average value of the first principal Lagrange strain was calculated for the middle third of the total length of the model.
Results: Statistical (stepwise) analysis revealed the effects of the degree of twist, other geometries, and their combinations on AT strain. The main findings were as follows: (1) a greater degree of twist resulted in higher average strains (t = 9.28, p < 0.0001) and (2) the effect of the degree of twist on the strain depended on dimensions of thickness of the most distal part of the AT (t = -4.49, p < 0.0001) and the length of the AT (t = -3.82, p = 0.0005). Specifically, when the thickness of the most distal part and length were large, the degree of twist had a small effect on the first principal Lagrange strain; however, when the thickness of the most distal part and length were small, a greater degree of twist results in higher first principal Lagrange strain.
Conclusion: These results indicate that the relationship between the degree of twist and local strain is complex and may not be accurately assessed by FE simulation using a single geometry. en-copyright= kn-copyright= en-aut-name=EnomotoShota en-aut-sei=Enomoto en-aut-mei=Shota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FuruuchiShunya en-aut-sei=Furuuchi en-aut-mei=Shunya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IshibashiTatsuki en-aut-sei=Ishibashi en-aut-mei=Tatsuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamadaShu en-aut-sei=Yamada en-aut-mei=Shu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OdaToshiaki en-aut-sei=Oda en-aut-mei=Toshiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Science and Technology, Keio University kn-affil= affil-num=3 en-affil=Graduate School of Science and Technology, Keio University kn-affil= affil-num=4 en-affil=Faculty of Science and Technology, Keio University kn-affil= affil-num=5 en-affil=Graduate School of Education, Hyogo University of Teacher Education kn-affil= en-keyword=achilles tendon kn-keyword=achilles tendon en-keyword=computational model kn-keyword=computational model en-keyword=small composite design kn-keyword=small composite design en-keyword=subtendon kn-keyword=subtendon en-keyword=tendinopathy kn-keyword=tendinopathy END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue=2 article-no= start-page=189 end-page=195 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=2023 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Prosthodontic treatment can improve the ingestible food profile in Japanese adult outpatients en-subtitle= kn-subtitle= en-abstract= kn-abstract=Purpose: To investigate the effect of prosthodontic treatment on the ingestible food profile in adult Japanese outpatients, and to identify the related risk factors that can deteriorate the profile.
Methods: The participants were 277 outpatients who visited university-based specialty clinics in Japan for prosthodontic treatment. The demographic data, number of present teeth assessed via intraoral examination, and oral health-related quality of life assessed by the total Oral Health Impact Profile (OHIP-J54) scores of all participants were recorded before treatment. Ingestible food profile score (IFS) was recorded using a validated food intake questionnaire. Eligible participants who answered the questionnaire before and after treatment were categorized into five groups based on the prosthodontic treatments they received (i.e., crowns, bridges, removable partial dentures, removable complete dentures, and removable complete and partial dentures).
Results: Multivariate analysis of covariance revealed a statistically significant main effect of prosthodontic intervention (time course: before and after treatment) on mean IFS (P=0.035, F=4.526), even after adjusting for covariates (age, number of present teeth, and treatment modality). Multiple linear regression analysis revealed that the low number of present teeth (r=0.427, P<0.001) and a high OHIP-J54 total score (r=-0.519, P<0.001) of the patients at the baseline were significantly associated with their baseline IFSs, even after adjusting for confounding variables.
Conclusions: The findings of this multicenter follow-up study indicate the importance of prosthodontic rehabilitation in improving patients’ ingestible food profiles. en-copyright= kn-copyright= en-aut-name=Kimura-OnoAya en-aut-sei=Kimura-Ono en-aut-mei=Aya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MaekawaKenji en-aut-sei=Maekawa en-aut-mei=Kenji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KubokiTakuo en-aut-sei=Kuboki en-aut-mei=Takuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NawachiKumiko en-aut-sei=Nawachi en-aut-mei=Kumiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=FujisawaMasanori en-aut-sei=Fujisawa en-aut-mei=Masanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SatoHironobu en-aut-sei=Sato en-aut-mei=Hironobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AitaHideki en-aut-sei=Aita en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KoyamaShigeto en-aut-sei=Koyama en-aut-mei=Shigeto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=HideshimaMasayuki en-aut-sei=Hideshima en-aut-mei=Masayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=SatoYuji en-aut-sei=Sato en-aut-mei=Yuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=WakeHiroyuki en-aut-sei=Wake en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=NagaoKan en-aut-sei=Nagao en-aut-mei=Kan kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=Kodaira-UedaYorika en-aut-sei=Kodaira-Ueda en-aut-mei=Yorika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=TamakiKatsushi en-aut-sei=Tamaki en-aut-mei=Katsushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=SadamoriShinsuke en-aut-sei=Sadamori en-aut-mei=Shinsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=TsugaKazuhiro en-aut-sei=Tsuga en-aut-mei=Kazuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= en-aut-name=NishiYasuhiro en-aut-sei=Nishi en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=17 ORCID= en-aut-name=SawaseTakashi en-aut-sei=Sawase en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=18 ORCID= en-aut-name=KoshinoHisashi en-aut-sei=Koshino en-aut-mei=Hisashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=19 ORCID= en-aut-name=MasumiShin-ichi en-aut-sei=Masumi en-aut-mei=Shin-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=20 ORCID= en-aut-name=SakuraiKaoru en-aut-sei=Sakurai en-aut-mei=Kaoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=21 ORCID= en-aut-name=IshibashiKanji en-aut-sei=Ishibashi en-aut-mei=Kanji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=22 ORCID= en-aut-name=OhyamaTakashi en-aut-sei=Ohyama en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=23 ORCID= en-aut-name=AkagawaYasumasa en-aut-sei=Akagawa en-aut-mei=Yasumasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=24 ORCID= en-aut-name=HiraiToshihiro en-aut-sei=Hirai en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=25 ORCID= en-aut-name=SasakiKeiichi en-aut-sei=Sasaki en-aut-mei=Keiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=26 ORCID= en-aut-name=KoyanoKiyoshi en-aut-sei=Koyano en-aut-mei=Kiyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=27 ORCID= en-aut-name=YataniHirofumi en-aut-sei=Yatani en-aut-mei=Hirofumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=28 ORCID= en-aut-name=MatsumuraHideo en-aut-sei=Matsumura en-aut-mei=Hideo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=29 ORCID= en-aut-name=IchikawaTetsuo en-aut-sei=Ichikawa en-aut-mei=Tetsuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=30 ORCID= en-aut-name=OhkawaShuji en-aut-sei=Ohkawa en-aut-mei=Shuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=31 ORCID= en-aut-name=BabaKazuyoshi en-aut-sei=Baba en-aut-mei=Kazuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=32 ORCID= affil-num=1 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital kn-affil= affil-num=2 en-affil=Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Meikai University School of Dentistry kn-affil= affil-num=6 en-affil=Fukuoka Dental College Graduate School of Dental Science kn-affil= affil-num=7 en-affil=Tohoku University Graduate School of Dentistry kn-affil= affil-num=8 en-affil=Tohoku University Graduate School of Dentistry, Japan kn-affil= affil-num=9 en-affil=Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences kn-affil= affil-num=10 en-affil=Showa University School of Dentistry kn-affil= affil-num=11 en-affil=Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences kn-affil= affil-num=12 en-affil=Tokushima University Graduate School of Biomedical Sciences kn-affil= affil-num=13 en-affil=Tokyo Dental College kn-affil= affil-num=14 en-affil=Kanagawa Dental University Graduate School kn-affil= affil-num=15 en-affil=Ministry of Health, Labour, and Welfare, Chugoku-Shikoku Regional Bureau of Health and Welfare kn-affil= affil-num=16 en-affil=Hiroshima University Graduate School of Biomedical and Health Sciences kn-affil= affil-num=17 en-affil=Kagoshima University Graduate School of Medical and Dental Sciences kn-affil= affil-num=18 en-affil=Nagasaki University Graduate School of Biomedical Sciences kn-affil= affil-num=19 en-affil=Health Sciences University of Hokkaido School of Dentistry kn-affil= affil-num=20 en-affil=Kyushu Dental University kn-affil= affil-num=21 en-affil=Tokyo Dental College kn-affil= affil-num=22 en-affil=Iwate Medical University School of Dentistry kn-affil= affil-num=23 en-affil=Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences kn-affil= affil-num=24 en-affil=Hiroshima University Graduate School of Biomedical and Health Sciences kn-affil= affil-num=25 en-affil=Health Sciences University of Hokkaido School of Dentistry kn-affil= affil-num=26 en-affil=Tohoku University Graduate School of Dentistry kn-affil= affil-num=27 en-affil=Kyushu University Faculty of Dental Science kn-affil= affil-num=28 en-affil=Osaka University Graduate School of Dentistry kn-affil= affil-num=29 en-affil=Nihon University School of Dentistry kn-affil= affil-num=30 en-affil=Tokushima University Graduate School of Biomedical Sciences kn-affil= affil-num=31 en-affil=Meikai University School of Dentistry kn-affil= affil-num=32 en-affil=Showa University School of Dentistry kn-affil= en-keyword=Dietary diversity kn-keyword=Dietary diversity en-keyword=Ingestible foods kn-keyword=Ingestible foods en-keyword=Oral-health quality of life kn-keyword=Oral-health quality of life en-keyword=Prosthodontic rehabilitation kn-keyword=Prosthodontic rehabilitation END start-ver=1.4 cd-journal=joma no-vol=61 cd-vols= no-issue=1 article-no= start-page=33 end-page=41 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230222 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Antimalarial effect of synthetic endoperoxide on synchronized Plasmodium chabaudi infected mice en-subtitle= kn-subtitle= en-abstract= kn-abstract=The discovery of new antimalarial drugs can be developed using asynchronized Plasmodium berghei malaria parasites in vivo in mice. Studies on a particular stage are also required to assess the effectiveness and mode of action of drugs. In this report, we used endoperoxide 6-(1,2,6,7-tetraoxaspiro [7.11] nonadec-4-yl) hexan-1-ol (N-251) as a model antimalarial compound on P. chabaudi parasites. We examined the antimalarial effect of N-251 against ring-stage- and trophozoite-stage-rich P. chabaudi parasites and asynchronized P. berghei parasites using the 4-day suppressive test. The ED50 values were 27, 22, and 22 mg/kg, respectively, and the antimalarial activity of N-251 was verified in both rodent malaria parasites. To assess the stage-specific effect of N-251 in vivo, we evaluated the change of parasitemia and distribution of parasite stages using ring-stage- and trophozoite-stage-rich P. chabaudi parasites with one-day drug administration for one life cycle. We discovered that the parasitemias decreased after 13 and 9 hours post-treatment in the ring-stage- and trophozoite-stage-rich groups, respectively. Additionally, in the ring-stage-rich N-251 treated group, the ring-stage parasites hindered trophozoite parasite development. For the trophozoite-stage-rich N-251 treated group, the distribution of the trophozoite stage was maintained without a change in parasitemia until 9 hours. Because of these findings, it can be concluded that N-251 suppressed the trophozoite stage but not the ring stage. We report for the first time that N-251 specifically suppresses the trophozoite stage using P. chabaudi in mice. The results show that P. chabaudi is a reliable model for the characterization of stage-specific antimalarial effects. en-copyright= kn-copyright= en-aut-name=AlyNagwa S. M. en-aut-sei=Aly en-aut-mei=Nagwa S. M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MatsumoriHiroaki en-aut-sei=Matsumori en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=DinhThi Quyen en-aut-sei=Dinh en-aut-mei=Thi Quyen kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SatoAkira en-aut-sei=Sato en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MiyoshiShin-Ichi en-aut-sei=Miyoshi en-aut-mei=Shin-Ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ChangKyung-Soo en-aut-sei=Chang en-aut-mei=Kyung-Soo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YuHak Sun en-aut-sei=Yu en-aut-mei=Hak Sun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KobayashiFumie en-aut-sei=Kobayashi en-aut-mei=Fumie kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KimHye-Sook en-aut-sei=Kim en-aut-mei=Hye-Sook kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil=Division of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Division of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Division of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Division of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Sanitary Microbiology, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= affil-num=6 en-affil=Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan kn-affil= affil-num=7 en-affil=Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University kn-affil= affil-num=8 en-affil=Department of Environmental Science, School of Life Environmental Science, Azabu University kn-affil= affil-num=9 en-affil=Division of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Plasmodium chabaudi kn-keyword=Plasmodium chabaudi en-keyword=synchronization kn-keyword=synchronization en-keyword=stage-specific activity kn-keyword=stage-specific activity en-keyword=antimalarial N-251 kn-keyword=antimalarial N-251 END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue=11 article-no= start-page=268 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241025 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The Change in Public Perception and Knowledge Acquisition Methods of Chronic Kidney Disease Among General Population in Okayama Prefecture, Japan en-subtitle= kn-subtitle= en-abstract= kn-abstract=CKD public education plays a very important role in effective chronic kidney disease (CKD) countermeasure. We have been conducting CKD public education programs in Okayama Prefecture since 2007. Here, we aimed to examine the actual status of CKD perceptance and changes in CKD perceptance due to these education programs. The study was conducted on individuals who underwent health checkups at 12 medical institutions across five medical regions in Okayama Prefecture between 1 October and 30 November in 2015, 2019, and 2023. The results showed that overall CKD perceptance has improved over time (perceptance of "CKD" 4% to 7%, "chronic kidney disease" 27% to 34%, 2015 vs. 2023). "Chronic kidney disease" was more commonly recognized than "CKD", and the elderly were more aware of the disease than younger people. The CKD perceptance improved across all age groups. However, the rate of CKD perceptance is still low, especially among young people. Previously, newspapers were the second most common resource of information about CKD after television. However, the Internet has recently replaced newspapers as the second most common source of information, especially among younger people. Understanding of the exact diagnosis of CKD also remains insufficient. It is necessary to continue more effective CKD public education programs through more intelligible terminology and information sources that match the demographics of target population. en-copyright= kn-copyright= en-aut-name=UmebayashiRyoko en-aut-sei=Umebayashi en-aut-mei=Ryoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=Matsuoka-UchiyamaNatsumi en-aut-sei=Matsuoka-Uchiyama en-aut-mei=Natsumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SugiyamaHitoshi en-aut-sei=Sugiyama en-aut-mei=Hitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ShikataKenichi en-aut-sei=Shikata en-aut-mei=Kenichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KashiharaNaoki en-aut-sei=Kashihara en-aut-mei=Naoki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MakinoHirofumi en-aut-sei=Makino en-aut-mei=Hirofumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=WadaJun en-aut-sei=Wada en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=UchidaHaruhito A. en-aut-sei=Uchida en-aut-mei=Haruhito A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Okayama University kn-affil= affil-num=5 en-affil=Kawasaki Geriatric Medical Center kn-affil= affil-num=6 en-affil=Okayama University kn-affil= affil-num=7 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=chronic kidney disease kn-keyword=chronic kidney disease en-keyword= CKD perceptance kn-keyword= CKD perceptance en-keyword= CKD public education programs kn-keyword= CKD public education programs END start-ver=1.4 cd-journal=joma no-vol=300 cd-vols= no-issue=6 article-no= start-page=107360 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=202406 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Nonspecific N-terminal tetrapeptide insertions disrupt the translation arrest induced by ribosome-arresting peptide sequences en-subtitle= kn-subtitle= en-abstract= kn-abstract=The nascent polypeptide chains passing through the ribosome tunnel not only serve as an intermediate of protein synthesis but also, in some cases, act as dynamic genetic information, controlling translation through interaction with the ribosome. One notable example is Escherichia coli SecM, in which translation of the ribosome arresting peptide (RAP) sequence in SecM leads to robust elongation arrest. Translation regulations, including the SecM-induced translation arrest, play regulatory roles such as gene expression control. Recent investigations have indicated that the insertion of a peptide sequence, SKIK (or MSKIK), into the adjacent N-terminus of the RAP sequence of SecM behaves as an "arrest canceler". As the study did not provide a direct assessment of the strength of translation arrest, we conducted detailed biochemical analyses. The results revealed that the effect of SKIK insertion on weakening SecM-induced translation arrest was not specific to the SKIK sequence, that is, other tetrapeptide sequences inserted just before the RAP sequence also attenuated the arrest. Our data suggest that SKIK or other tetrapeptide insertions disrupt the context of the RAP sequence rather than canceling or preventing the translation arrest. en-copyright= kn-copyright= en-aut-name=KoboAkinao en-aut-sei=Kobo en-aut-mei=Akinao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TaguchiHideki en-aut-sei=Taguchi en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ChadaniYuhei en-aut-sei=Chadani en-aut-mei=Yuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=School of Life Science and Technology, Tokyo Institute of Technology kn-affil= affil-num=2 en-affil=School of Life Science and Technology, Tokyo Institute of Technology kn-affil= affil-num=3 en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=61 cd-vols= no-issue=3 article-no= start-page=282 end-page=291 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230821 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evaluating the activity of N-89 as an oral antimalarial drug en-subtitle= kn-subtitle= en-abstract= kn-abstract=Despite the recent progress in public health measures, malaria remains a troublesome disease that needs to be eradicated. It is essential to develop new antimalarial medications that are reliable and secure. This report evaluated the pharmacokinetics and antimalarial activity of 1,2,6,7-tetraoxaspiro[7.11]nonadecane (N-89) using the rodent malaria parasite Plasmodium berghei in vivo. After a single oral dose (75 mg/kg) of N-89, its pharmacokinetic parameters were measured, and t1/2 was 0.97 h, Tmax was 0.75 h, and bioavailability was 7.01%. A plasma concentration of 8.1 ng/ml of N-89 was maintained for 8 h but could not be detected at 10 h. The dose inhibiting 50% of parasite growth (ED50) and ED90 values of oral N-89 obtained following a 4-day suppressive test were 20 and 40 mg/kg, respectively. Based on the plasma concentration of N-89, we evaluated the antimalarial activity and cure effects of oral N-89 at a dose of 75 mg/kg 3 times daily for 3 consecutive days in mice harboring more than 0.5% parasitemia. In all the N-89- treated groups, the parasites were eliminated on day 5 post-treatment, and all mice recovered without a parasite recurrence for 30 days. Additionally, administering oral N-89 at a low dose of 50 mg/kg was sufficient to cure mice from day 6 without parasite recurrence. This work was the first to investigate the pharmacokinetic characteristics and antimalarial activity of N-89 as an oral drug. In the future, the following steps should be focused on developing N-89 for malaria treatments; its administration schedule and metabolic pathways should be investigated. en-copyright= kn-copyright= en-aut-name=AlyNagwa S. M. en-aut-sei=Aly en-aut-mei=Nagwa S. M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MatsumoriHiroaki en-aut-sei=Matsumori en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=DinhThi Quyen en-aut-sei=Dinh en-aut-mei=Thi Quyen kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SatoAkira en-aut-sei=Sato en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MiyoshiShin-ichi en-aut-sei=Miyoshi en-aut-mei=Shin-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ChangKyung-Soo en-aut-sei=Chang en-aut-mei=Kyung-Soo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YuHak Sun en-aut-sei=Yu en-aut-mei=Hak Sun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KubotaTakaaki en-aut-sei=Kubota en-aut-mei=Takaaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KurosakiYuji en-aut-sei=Kurosaki en-aut-mei=Yuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=CaoDuc Tuan en-aut-sei=Cao en-aut-mei=Duc Tuan kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=RashedGehan A. en-aut-sei=Rashed en-aut-mei=Gehan A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=KimHye-Sook en-aut-sei=Kim en-aut-mei=Hye-Sook kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= affil-num=1 en-affil=Department of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Sanitary Microbiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=6 en-affil=Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan kn-affil= affil-num=7 en-affil=Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University kn-affil= affil-num=8 en-affil=Department of Natural Products Chemistry, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=9 en-affil=Department of Pharmaceutical Formulation Design, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=10 en-affil=Department of Pharmaceutical Chemistry and Quality Control, Faculty of Pharmacy, Hai Phong University of Medicine and Pharmacy kn-affil= affil-num=11 en-affil=Department of Parasitology, Benha Faculty of Medicine, Benha University kn-affil= affil-num=12 en-affil=Department of International Infectious Diseases Control, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=New antimalarial candidate kn-keyword=New antimalarial candidate en-keyword=oral N-89 kn-keyword=oral N-89 en-keyword=pharmacokinetics kn-keyword=pharmacokinetics en-keyword=in vivo kn-keyword=in vivo END start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue=3 article-no= start-page=284 end-page=291 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=2023 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Transversal Survey of Emergency Medicine Policy and Quality Metrics in Japan' s Regional Health Care Plans en-subtitle= kn-subtitle= en-abstract= kn-abstract=Introduction: It is essential to establish appropriate medical quality metrics and make improvements to safely and efficiently deliver optimum emergency medical services. The Ministry of Health, Labor and Welfare (MHLW) recommends prefectures to establish numerical quality metrics in their regional healthcare plans (RHCP). The 7th RHCP was issued by the MHLW in 2017 along with a notice of planning in covering the six-year period from 2018 to 2023. In this descriptive study, the emergency medicine policies in the 7th RHCP of each prefecture were analyzed from a quality improvement perspective.
Method: The authors examined the chapters on emergency medicine in the RHCPs of 47 prefectural governments for the overall structure, cost-benefits, and connection to community-based integrated care systems. The type and number of clinical measures listed as numerical metrics and their classification methods were emphasized.
Result: Regarding the overall plan structure, 40 prefectural governments began their description with an analysis of current surroundings. In total, 24 prefectural governments mentioned community-based integrated care systems but none mentioned cost-benefit analysis. Altogether, only 43 of 47 prefectural governments (91%) indicated numerical metrics. The maximum number of numerical targets for quality measures by prefecture was 19, the minimum was 0, and the median was 4 (IQR: 3-6.5); there were 220 metrics in total, with 82 structural, 96 process, and 42 outcome measures. Additionally, 13 prefectures (28%) classified quality measures according to the MHLW’s guidance, 6 (13%) used their own classification manner, while the others did not classify their measures.
Conclusions: There were significant differences in emergency medicine policies and quality metrics among the prefectural governments. Further research is needed to develop and establish more comprehensive and appropriate metrics based on a common methodology to improve the quality of emergency medicine. en-copyright= kn-copyright= en-aut-name=IidaAtsuyoshi en-aut-sei=Iida en-aut-mei=Atsuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SaitoShinya en-aut-sei=Saito en-aut-mei=Shinya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HamadaJun en-aut-sei=Hamada en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NakamuraShunsuke en-aut-sei=Nakamura en-aut-mei=Shunsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NojimaTsuyoshi en-aut-sei=Nojima en-aut-mei=Tsuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NaitoHiromichi en-aut-sei=Naito en-aut-mei=Hiromichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MikaneTakeshi en-aut-sei=Mikane en-aut-mei=Takeshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Graduate School of Health Sciences, Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Health and Welfare Services Management, Kawasaki University of Medical Welfare kn-affil= affil-num=4 en-affil=Department of Emergency Medicine, Japanese Red Cross Okayama Hospital kn-affil= affil-num=5 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Emergency Medicine, Japanese Red Cross Okayama Hospital kn-affil= en-keyword=emergency medicine kn-keyword=emergency medicine en-keyword=indicator kn-keyword=indicator en-keyword=measure kn-keyword=measure en-keyword=quality assurance kn-keyword=quality assurance en-keyword=quality improvement kn-keyword=quality improvement END start-ver=1.4 cd-journal=joma no-vol=36 cd-vols= no-issue=10 article-no= start-page=4585 end-page=4606 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241029 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Mobile Augmented Reality Interface for Instruction-based Disaster Preparedness Guidelines en-subtitle= kn-subtitle= en-abstract= kn-abstract=Disaster preparedness guidelines help citizens protect themselves against disasters. Nonetheless, the general public has been found not to read them. Augmented reality (AR) interfaces are known to improve knowledge transfer in studies of education, industry, and elderly assistance. However, this is achieved this by creating specific interfaces for users, not the general public. To test the performance of these interfaces for general public guidance, we designed and implemented a novel AR-assisted disaster prevention guideline that leverages object detection models to identify targets of disaster preparedness advice. We then had a diverse-age audience compare our design against a real traditional paper-based preparedness guide in a room arranged as a common remote work bedroom. By testing their usability, task load, and capacity to make users aware of their environmental hazards, we gained important insights into the performance of different age groups following media developed for the general public. Regardless of different age groups achieving similar usability scores, we found minors improving their performance scores with our novel interface and adults from 20 to 49 years old seemingly performing better than other age groups. In this study, we highlight the importance of guidance alternatives for the young and the less-technology-aware population, contributing to the under-explored area of AR interfaces for the general public. en-copyright= kn-copyright= en-aut-name=AguilarSergio De León en-aut-sei=Aguilar en-aut-mei=Sergio De León kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MatsudaYuki en-aut-sei=Matsuda en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YasumotoKeiichi en-aut-sei=Yasumoto en-aut-mei=Keiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Information Science, Nara Institute of Science and Technology kn-affil= affil-num=2 en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Information Science, Nara Institute of Science and Technology kn-affil= en-keyword=guidelines kn-keyword=guidelines en-keyword=augmented reality kn-keyword=augmented reality en-keyword=disaster preparedness kn-keyword=disaster preparedness en-keyword=object recognition kn-keyword=object recognition en-keyword=user interface kn-keyword=user interface en-keyword=knowledge transfer kn-keyword=knowledge transfer END start-ver=1.4 cd-journal=joma no-vol=24 cd-vols= no-issue=1 article-no= start-page=366 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241120 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The required experience of open pancreaticoduodenectomy before becoming a specialist in hepatobiliary and pancreatic surgeons: a multicenter, cohort study of 334 open pancreaticoduodenectomies en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background Open pancreaticoduodenectomy (OPD) is an essential surgical procedure for expert hepato-biliary-pancreatic (HBP) surgeons. However, there is no standard for how many surgeries must be performed by a surgeon in training before they are considered to have enough experience to ensure surgical safety.
Methods Cumulative Sum (CUSUM) analysis was performed using the surgical data of OPDs performed during the training period of board-certified expert surgeons of the Japanese Society of Hepato-Biliary-Pancreatic Surgery.
Results Fourteen HBP surgeons participated in this study and performed 334 OPDs during their training period. The median (interquartile range) values for operative time, blood loss, and length of hospital stay were 455 (397-519) minutes, 450 (234--716) ml, and 28 (21-38) days, respectively. CUSUM analysis showed inflection points at 20 surgeries performed for operative time. After 20 procedures, operative time was significantly shorter (461 min vs. 425 min, p = 0.021) and blood loss was significantly lower (470 ml vs. 340 ml, p = 0.038). No significant differences between within 20 and after 21 procedures were found in the complication rate (53% vs. 48%, p = 0.424) and rate of in-hospital deaths (1.5% vs.1.4%. p = 0.945). Up to 20 surgeries, PDAC and another malignant tumor had longer operative time than benign/low malignant diseases (486 min vs. 472 min vs. 429 min, p < 0.001), and higher blood loss (500 ml vs. 502 ml vs. 355 ml, p < 0.001). Mortality rate was higher at PDAC cases (5% vs. 0% vs. 0%, p = 0.01). After the 21 procedures, these outcomes were improved and no differences in by primary disease were observed. Multivariable analysis showed that within 20 surgeries were independent risk factors of longer operative time (HR2.6, p = 0.013) and higher blood loss (HR2.0, p = 0.049).
Conclusions To stabilize the surgical outcome of OPD for malignant disease, at least 20 surgeries should be performed at a certified institution during surgeon training. Trial registrationClinical trial number: Not applicable. en-copyright= kn-copyright= en-aut-name=FujiTomokazu en-aut-sei=Fuji en-aut-mei=Tomokazu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=UmedaYuzo en-aut-sei=Umeda en-aut-mei=Yuzo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TakagiKosei en-aut-sei=Takagi en-aut-mei=Kosei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HiokiMasayoshi en-aut-sei=Hioki en-aut-mei=Masayoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YoshidaRyuichi en-aut-sei=Yoshida en-aut-mei=Ryuichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=EndoYoshikatsu en-aut-sei=Endo en-aut-mei=Yoshikatsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YasuiKazuya en-aut-sei=Yasui en-aut-mei=Kazuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NobuokaDaisuke en-aut-sei=Nobuoka en-aut-mei=Daisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=MitsuhashiToshiharu en-aut-sei=Mitsuhashi en-aut-mei=Toshiharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Gastroenterological Surgery Dentistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Gastroenterological Surgery Dentistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Gastroenterological Surgery Dentistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Surgery, Fukuyama City Hospital kn-affil= affil-num=5 en-affil=Department of surgery, Hiroshima Citizens Hiroshima Citizens Hospital kn-affil= affil-num=6 en-affil=Department of Surgery, Japanese Red Cross Society Himeji Hospital kn-affil= affil-num=7 en-affil=Department of Gastroenterological Surgery Dentistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Gastroenterological Surgery, Kagawa Prefectural Central Hospital kn-affil= affil-num=9 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital kn-affil= affil-num=10 en-affil=Department of Gastroenterological Surgery Dentistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= en-keyword=Education kn-keyword=Education en-keyword=High-volume hospital kn-keyword=High-volume hospital en-keyword=Learning curve kn-keyword=Learning curve en-keyword=Pancreaticoduodenectomy kn-keyword=Pancreaticoduodenectomy END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue=11 article-no= start-page=upae196 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241022 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=SNAr hexafluoroisopropoxylation of electron-rich aryl fluoride with a catalytic electrical input en-subtitle= kn-subtitle= en-abstract= kn-abstract=Anodic oxidation–promoted SNAr reactions of electron-rich aryl fluoride were developed. The anodic oxidation of 4-fluoroanisole in hexafluoroisopropyl alcohol (HFIP) with K2CO3 led to SNAr-type hexafluoroisopropoxylation, and the reaction was completed with a catalytic electrical input. The results of cyclic voltammetry suggest that the radical cation of 4-fluoroanisole, which would react with the alkoxide of HFIP, is generated. Electron transfer between the intermediate and the starting material constructs the catalytic cycle, and the elimination of fluoride from the Meisenheimer complex produces the desired compound. en-copyright= kn-copyright= en-aut-name=SatoEisuke en-aut-sei=Sato en-aut-mei=Eisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NakahamaTomohiro en-aut-sei=Nakahama en-aut-mei=Tomohiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MitsudoKoichi en-aut-sei=Mitsudo en-aut-mei=Koichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SugaSeiji en-aut-sei=Suga en-aut-mei=Seiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= en-keyword=anodic oxidation kn-keyword=anodic oxidation en-keyword=organic electrochemistry kn-keyword=organic electrochemistry en-keyword=SNAr reaction kn-keyword=SNAr reaction END start-ver=1.4 cd-journal=joma no-vol=169 cd-vols= no-issue= article-no= start-page=106712 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20249 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The parallel stack loading problem of minimizing the exact number of relocations en-subtitle= kn-subtitle= en-abstract= kn-abstract=This study addresses the parallel stack loading problem, a general optimization problem arising in storage facilities such as container yards, slab yards, and warehouses. In this problem, we load incoming items into parallel stacks in the loading phase to minimize the number of relocations in the subsequent retrieval phase. Because of difficulties in treating the nested problem structure originating from the mutual dependence of the two phases, the existing studies approximately minimized the number of relocations using surrogate objective functions. In contrast, this study considers the parallel stack loading problem aiming to minimize the exact number of relocations. We first provide an integer programming formulation and next develop a nested branch-and-bound algorithm. In a computational study, we verify the effectiveness of the proposed branch-and-bound algorithm and evaluate the known surrogate objective functions based on the exact minimization. en-copyright= kn-copyright= en-aut-name=TanakaShunji en-aut-sei=Tanaka en-aut-mei=Shunji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ElWakilMohamed en-aut-sei=ElWakil en-aut-mei=Mohamed kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=EltawilAmr en-aut-sei=Eltawil en-aut-mei=Amr kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Environmental, Life and Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Department of Production Engineering and Mechanical Design, Faculty of Engineering, Tanta University kn-affil= affil-num=3 en-affil=Department of Industrial and Manufacturing Engineering, Egypt Japan University of Science and Technology kn-affil= en-keyword=Logistics kn-keyword=Logistics en-keyword=Parallel stack loading problem kn-keyword=Parallel stack loading problem en-keyword=Relocation kn-keyword=Relocation en-keyword=Integer programming kn-keyword=Integer programming en-keyword=Branch-and-bound algorithm kn-keyword=Branch-and-bound algorithm END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=21 article-no= start-page=11592 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241029 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Epigenetic Regulation of CXC Chemokine Expression by Environmental Electrophiles Through DNA Methyltransferase Inhibition en-subtitle= kn-subtitle= en-abstract= kn-abstract=Ubiquitously distributed environmental electrophiles covalently modify DNA and proteins, potentially leading to adverse health effects. However, the impacts of specific electrophiles on target proteins and their physiological roles remain largely unknown. In the present study, we focused on DNA methylation, which regulates gene expression and physiological responses. A total of 45 environmental electrophiles were screened for inhibitory effects on the activity of DNA methyltransferase 3B (DNMT3B), a key enzyme in DNA methylation, and four compounds were identified. We focused on 1,2-naphthoquinone (1,2-NQ), an air pollutant whose toxicity has been reported previously. Interestingly, we found that 1,2-NQ modified multiple lysine and histidine residues in DNMT3B, one of which was near the active site in DNMT3B. It was found that 1,2-NQ altered gene expression and evoked inflammatory responses in lung adenocarcinoma cell lines. Furthermore, we found that 1,2-NQ upregulated CXCL8 expression through DNA demethylation of the distal enhancer and promoted cancer cell growth. Our study reveals novel mechanisms of epigenetic regulation by environmental electrophiles through the inhibition of DNMT3B activity and suggests their physiological impact. en-copyright= kn-copyright= en-aut-name=TsuchidaTomoki en-aut-sei=Tsuchida en-aut-mei=Tomoki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KubotaSho en-aut-sei=Kubota en-aut-mei=Sho kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KamiuezonoShizuki en-aut-sei=Kamiuezono en-aut-mei=Shizuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TakasugiNobumasa en-aut-sei=Takasugi en-aut-mei=Nobumasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ItoAkihiro en-aut-sei=Ito en-aut-mei=Akihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KumagaiYoshito en-aut-sei=Kumagai en-aut-mei=Yoshito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=UeharaTakashi en-aut-sei=Uehara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Medicinal Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=School of Life Sciences, Tokyo University of Pharmacy and Life Sciences kn-affil= affil-num=6 en-affil=Graduate School of Pharmaceutical Sciences, Kyushu University kn-affil= affil-num=7 en-affil=Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=DNA methylation kn-keyword=DNA methylation en-keyword=DNA methyltransferase kn-keyword=DNA methyltransferase en-keyword=chemical modification kn-keyword=chemical modification en-keyword=chemokine kn-keyword=chemokine en-keyword=cell proliferation kn-keyword=cell proliferation en-keyword=toxicology kn-keyword=toxicology en-keyword=exposome kn-keyword=exposome en-keyword=environmental electrophiles kn-keyword=environmental electrophiles END start-ver=1.4 cd-journal=joma no-vol=2024 cd-vols= no-issue=11 article-no= start-page=113D01 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241026 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Measurement of γ-Rays Generated by Neutron Interaction with 16O at 30 MeV and 250 MeV en-subtitle= kn-subtitle= en-abstract= kn-abstract=Deep understanding of γ-ray production from the fast neutron reaction in water is crucial for various physics studies at large-scale water Cherenkov detectors. We performed test experiments using quasi-mono energetic neutron beams (⁠En = 30 and 250 MeV) at Osaka University’s Research Center for Nuclear Physics to measure γ-rays originating from the neutron–oxygen reaction with a high-purity germanium detector. Multiple γ-ray peaks which are expected to be from excited nuclei after the neutron–oxygen reaction were successfully observed. We measured the neutron beam flux using an organic liquid scintillator for the cross section measurement. With a spectral fitting analysis based on the tailored γ-ray signal and background templates, we measured cross sections for each observed γ-ray component. The results will be useful to validate neutron models employed in ongoing and future water Cherenkov experiments. en-copyright= kn-copyright= en-aut-name=TanoT. en-aut-sei=Tano en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HoraiT. en-aut-sei=Horai en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AshidaY. en-aut-sei=Ashida en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HinoY. en-aut-sei=Hino en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=IacobF. en-aut-sei=Iacob en-aut-mei=F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MaurelA. en-aut-sei=Maurel en-aut-mei=A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MoriM. en-aut-sei=Mori en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=CollazuolG. en-aut-sei=Collazuol en-aut-mei=G. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KonakaA. en-aut-sei=Konaka en-aut-mei=A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=KoshioY. en-aut-sei=Koshio en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=NakayaT. en-aut-sei=Nakaya en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=ShimaT. en-aut-sei=Shima en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=WendellR. en-aut-sei=Wendell en-aut-mei=R. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= affil-num=1 en-affil=Department of Physics, Okayama University kn-affil= affil-num=2 en-affil=Department of Physics, Okayama University kn-affil= affil-num=3 en-affil=Department of Physics and Astronomy, University of Utah kn-affil= affil-num=4 en-affil=Department of Physics, Okayama University kn-affil= affil-num=5 en-affil=Department of Physics and Astronomy, University of Padova kn-affil= affil-num=6 en-affil=Ecole Polytechnique, IN2P3-CNRS, Laboratoire Leprince-Ringuet kn-affil= affil-num=7 en-affil=National Astronomical Observatory of Japan kn-affil= affil-num=8 en-affil=Department of Physics and Astronomy, University of Padova kn-affil= affil-num=9 en-affil=TRIUMF kn-affil= affil-num=10 en-affil=Department of Physics, Okayama University kn-affil= affil-num=11 en-affil=Department of Physics, Kyoto University kn-affil= affil-num=12 en-affil=Research Center for Nuclear Physics (RCNP) kn-affil= affil-num=13 en-affil=Department of Physics, Kyoto University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=13 cd-vols= no-issue= article-no= start-page=318 end-page=326 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=2024 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Effects of Region-Specific Material Properties of Patellar Tendon on the Magnitude and Distribution of Local Stress and Strain en-subtitle= kn-subtitle= en-abstract= kn-abstract=The effects of the region-specific material properties of the patellar tendon (PT) on the magnitude and distribution of local stress and strain are poorly understood. Hence, this study investigated this issue using finite element analysis. A three-dimensional PT model was developed based on parameters obtained from previous studies, and was bisected in the frontal plane. Two models were created: one that considered region-specific material properties (two-material model) and one that did not (one-material model). An 8% strain was applied to the proximal surface, and the mean and peak first principal stress and strain were calculated. In the two-material model, the mean first principal stress observed in the anterior region was 28.5% higher than that in the posterior region. However, in the one-material model, the mean first principal stress in the anterior region was 19.5% lower than that in the posterior region. Focusing on the differences between the models, the mean and peak first principal stresses in the posterior region of the one-material model were 61.1% and 41.2% higher, respectively, compared with those in the two-material model. Furthermore, the mean and peak first principal stresses in the proximal and distal regions of the posterior region in the one-material model were 41.8-75.8% higher than those in the two-material model. These results suggest that the region-specific material properties of PT influence the stress distribution and underscore the importance of modeling that incorporates region-specific material properties in PT finite element models. en-copyright= kn-copyright= en-aut-name=EnomotoShota en-aut-sei=Enomoto en-aut-mei=Shota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OdaToshiaki en-aut-sei=Oda en-aut-mei=Toshiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Education, Hyogo University of Teacher Education kn-affil= en-keyword=computational model kn-keyword=computational model en-keyword=Mooney-Rivlin model kn-keyword=Mooney-Rivlin model en-keyword=soft tissue. kn-keyword=soft tissue. END start-ver=1.4 cd-journal=joma no-vol=300 cd-vols= no-issue=3 article-no= start-page=105679 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=202403 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Methyl vinyl ketone and its analogs covalently modify PI3K and alter physiological functions by inhibiting PI3K signaling en-subtitle= kn-subtitle= en-abstract= kn-abstract=Reactive carbonyl species (RCS), which are abundant in the environment and are produced in vivo under stress, covalently bind to nucleophilic residues such as Cys in proteins. Disruption of protein function by RCS exposure is predicted to play a role in the development of various diseases such as cancer and metabolic disorders, but most studies on RCS have been limited to simple cytotoxicity validation, leaving their target proteins and resulting physiological changes unknown. In this study, we focused on methyl vinyl ketone (MVK), which is one of the main RCS found in cigarette smoke and exhaust gas. We found that MVK suppressed PI3K-Akt signaling, which regulates processes involved in cellular homeostasis, including cell proliferation, autophagy, and glucose metabolism. Interestingly, MVK inhibits the interaction between the epidermal growth factor receptor and PI3K. Cys656 in the SH2 domain of the PI3K p85 subunit, which is the covalently binding site of MVK, is important for this interaction. Suppression of PI3K- Akt signaling by MVK reversed epidermal growth factor- induced negative regulation of autophagy and attenuated glucose uptake. Furthermore, we analyzed the effects of the 23 RCS compounds with structures similar to MVK and showed that their analogs also suppressed PI3K-Akt signaling in a manner that correlated with their similarities to MVK. Our study demonstrates the mechanism of MVK and its analogs in suppressing PI3K-Akt signaling and modulating physiological functions, providing a model for future studies analyzing environmental reactive species. en-copyright= kn-copyright= en-aut-name=MorimotoAtsushi en-aut-sei=Morimoto en-aut-mei=Atsushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakasugiNobumasa en-aut-sei=Takasugi en-aut-mei=Nobumasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=PanYuexuan en-aut-sei=Pan en-aut-mei=Yuexuan kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KubotaSho en-aut-sei=Kubota en-aut-mei=Sho kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=DohmaeNaoshi en-aut-sei=Dohmae en-aut-mei=Naoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=AbikoYumi en-aut-sei=Abiko en-aut-mei=Yumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=UchidaKoji en-aut-sei=Uchida en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KumagaiYoshito en-aut-sei=Kumagai en-aut-mei=Yoshito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=UeharaTakashi en-aut-sei=Uehara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil=Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Biomolecular Characterization Unit, Technology Platform Division, RIKEN Center for Sustainable Resource Science kn-affil= affil-num=6 en-affil=Graduate School of Biomedical Science, Nagasaki University kn-affil= affil-num=7 en-affil=Laboratory of Food Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo kn-affil= affil-num=8 en-affil=Graduate School of Pharmaceutical Sciences, Kyushu University kn-affil= affil-num=9 en-affil=Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=phosphatidylinositol 3-kinase (PI 3-kinase) kn-keyword=phosphatidylinositol 3-kinase (PI 3-kinase) en-keyword=cell signaling kn-keyword=cell signaling en-keyword=chemical modification kn-keyword=chemical modification en-keyword=autophagy kn-keyword=autophagy en-keyword=glucose uptake kn-keyword=glucose uptake END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue= article-no= start-page=e58753 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240923 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Enhancing Medical Interview Skills Through AI-Simulated PatientInteractions:Nonrandomized Controlled Trial en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: Medical interviewing is a critical skill in clinical practice, yet opportunities for practical training are limited in Japanese medical schools, necessitating urgent measures. Given advancements in artificial intelligence (AI) technology, its application in the medical field is expanding. However, reports on its application in medical interviews in medical education are scarce.
Objective: This study aimed to investigate whether medical students' interview skills could be improved by engaging with Al-simulated patients using large language models, including the provision of feedback.
Methods: This nonrandomized controlled trial was conducted with fourth-year medical students in Japan. A simulation program using large language models was provided to 35 students in the intervention group in 2023, while 110 students from 2022 who did not participate in the intervention were selected as the control group. The primary outcome was the score on the Pre-Clinical Clerkship Objective Structured Clinical Examination (pre-CC OSCE), a national standardized clinical skills examination, in medical interviewing. Secondary outcomes included surveys such as the Simulation-Based Training Quality Assurance Tool (SBT-QA10), administered at the start and end of the study.
Results: The Al intervention group showed significantly higher scores on medical interviews than the control group (Al group vs control group: mean 28.1, SD 1.6 vs 27.1, SD 2.2; P=.01). There was a trend of inverse correlation between the SBT-QA10 and pre-CC OSCE scores (regression coefficient-2.0 to-2.1). No significant safety concerns were observed.
Conclusions: Education through medical interviews using Al-simulated patients has demonstrated safety and a certain level of educational effectiveness. However, at present, the educational effects of this platform on nonverbal communication skills are limited, suggesting that it should be used as a supplementary tool to traditional simulation education. en-copyright= kn-copyright= en-aut-name=YamamotoAkira en-aut-sei=Yamamoto en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KodaMasahide en-aut-sei=Koda en-aut-mei=Masahide kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OgawaHiroko en-aut-sei=Ogawa en-aut-mei=Hiroko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MiyoshiTomoko en-aut-sei=Miyoshi en-aut-mei=Tomoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MaedaYoshinobu en-aut-sei=Maeda en-aut-mei=Yoshinobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=InoHideo en-aut-sei=Ino en-aut-mei=Hideo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Department of Hematology and Oncology, Okayama University Hospital kn-affil= affil-num=2 en-affil=Co-learning Community Healthcare Re-innovation Office, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Primary Care and Medical Education, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine kn-affil= affil-num=4 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Hematology and Oncology, Okayama University Hospital kn-affil= affil-num=6 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Center for Education in Medicine and Health Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=medical interview kn-keyword=medical interview en-keyword=generative pretrained transformer kn-keyword=generative pretrained transformer en-keyword=large language model kn-keyword=large language model en-keyword=simulation-based learning kn-keyword=simulation-based learning en-keyword=OSCE kn-keyword=OSCE en-keyword=artificial intelligence kn-keyword=artificial intelligence en-keyword=medical education kn-keyword=medical education en-keyword=simulated patients kn-keyword=simulated patients en-keyword=nonrandomized controlled trial kn-keyword=nonrandomized controlled trial END start-ver=1.4 cd-journal=joma no-vol=47 cd-vols= no-issue=10 article-no= start-page=1600 end-page=1609 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241001 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Molecular Diversity of Photosensitive Protein Opsins and Their High Potential for Optogenetic Applications en-subtitle= kn-subtitle= en-abstract= kn-abstract=Because G protein coupled receptors (GPCRs) represent the largest family of drug targets in clinical trials, GPCR signaling cascades are closely related to various physiological phenomena, attracting significant attention in pharmaceutical science. Opsins (also known as animal rhodopsins) are photoreceptive proteins containing retinal as a chromophore, which function as GPCRs and underlie the molecular basis of photoreception in animals. Recently, opsins have been progressively applied in an innovative technology called optogenetics to regulate biological activities using light. A wide variety of opsins have been identified in metazoans and characterized at the molecular and physiological levels, providing a foundation for their optogenetic applications. In this review, I briefly introduce the diversity of opsins in terms of their molecular functions, including G protein selectivity and photoreaction properties. This diversity provides a significant advantage for optically manipulating a wide variety of GPCR signaling cascades with high temporal resolution. Additionally, I discuss the rich array of opsin-based optogenetic tools used to control various physiological processes and their potential as therapeutic tools for vision restoration. Based on the introduction, I expect that the optogenetic approach will offer powerful tools to provide valuable insights into the molecular mechanisms of various physiological phenomena and next-generation treatment options for diseases beyond the capacity of traditional drugs. en-copyright= kn-copyright= en-aut-name=KojimaKeiichi en-aut-sei=Kojima en-aut-mei=Keiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=78 cd-vols= no-issue=5 article-no= start-page=357 end-page=362 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=202410 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Factors Affecting Dynamic Postural Control Ability in Adolescent Idiopathic Scoliosis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Research on postural control in patients with adolescent idiopathic scoliosis (AIS) has focused on static postural control, with few studies assessing dynamic postural control. We aimed to identify factors affecting index of postural stability (IPS), a dynamic postural control parameter, in patients with AIS. The participants comprised 50 female patients with AIS. We measured the IPS using stabilometry to evaluate dynamic postural control ability. We investigated age of the participants, major curve position (thoracic or thoracolumbar/lumbar), Cobb angle, and coronal balance. We then assessed the relationships between stabilometry parameters and other variables. IPS was analyzed with a linear regression model. Coronal balance, major curve position, and age each correlated with dynamic postural control ability. The Cobb angle showed no correlation with any of the parameters. Our results offer new insights into the assessment of postural control in patients with AIS. en-copyright= kn-copyright= en-aut-name=YamawakiRyoko en-aut-sei=Yamawaki en-aut-mei=Ryoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OdaYoshiaki en-aut-sei=Oda en-aut-mei=Yoshiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YamaneShuhei en-aut-sei=Yamane en-aut-mei=Shuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=UotaniKoji en-aut-sei=Uotani en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MisawaHaruo en-aut-sei=Misawa en-aut-mei=Haruo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KatayamaYoshimi en-aut-sei=Katayama en-aut-mei=Yoshimi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=HamadaMasanori en-aut-sei=Hamada en-aut-mei=Masanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=OzakiToshifumi en-aut-sei=Ozaki en-aut-mei=Toshifumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Division of Physical Medicine and Rehabilitation, Okayama University kn-affil= affil-num=2 en-affil=Department of Orthopaedic Surgery, Science of Functional Recovery and Reconstruction, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Division of Physical Medicine and Rehabilitation, Okayama University kn-affil= affil-num=4 en-affil=Department of Orthopaedic Surgery, Okayama University kn-affil= affil-num=5 en-affil=Ryusoh Orthopaedic Hospital kn-affil= affil-num=6 en-affil=Division of Physical Medicine and Rehabilitation, Okayama University kn-affil= affil-num=7 en-affil=Division of Physical Medicine and Rehabilitation, Okayama University kn-affil= affil-num=8 en-affil=Division of Physical Medicine and Rehabilitation, Okayama University kn-affil= en-keyword=adolescent idiopathic scoliosis kn-keyword=adolescent idiopathic scoliosis en-keyword=postural control kn-keyword=postural control en-keyword=coronal balance kn-keyword=coronal balance en-keyword=index of postural stability kn-keyword=index of postural stability en-keyword=stabilometry kn-keyword=stabilometry END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue=1 article-no= start-page=018003 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240127 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Design and performance of a gain calibration system for the POLARBEAR-2a receiver system at the Simons Array cosmic microwave background experiment en-subtitle= kn-subtitle= en-abstract= kn-abstract=We present an advanced system for calibrating the detector gain responsivity with a chopped thermal source for POLARBEAR-2a, which is the first receiver system of a cosmic microwave background (CMB) polarimetry experiment: the Simons Array. Intensity-to-polarization leakage due to calibration errors between detectors can be a significant source of systematic error for a polarization-sensitive experiment. To suppress this systematic uncertainty, POLARBEAR-2a calibrates the detector gain responsivities by observing a chopped thermal source before and after each period of science observations. The system includes a high-temperature ceramic heater that emits blackbody radiation covering a wide frequency range and an optical chopper to modulate the radiation signal. We discuss the experimental requirements of gain calibration and system design to calibrate POLARBEAR-2a. We evaluate the performance of our system during the early commissioning of the receiver system. This calibration system is promising for the future generation of CMB ground-based polarization observations. en-copyright= kn-copyright= en-aut-name=KanekoDaisuke en-aut-sei=Kaneko en-aut-mei=Daisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakatoriSayuri en-aut-sei=Takatori en-aut-mei=Sayuri kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HasegawaMasaya en-aut-sei=Hasegawa en-aut-mei=Masaya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HazumiMasashi en-aut-sei=Hazumi en-aut-mei=Masashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=InoueYuki en-aut-sei=Inoue en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=JeongOliver en-aut-sei=Jeong en-aut-mei=Oliver kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KatayamaNobuhiko en-aut-sei=Katayama en-aut-mei=Nobuhiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=LeeAdrian T. en-aut-sei=Lee en-aut-mei=Adrian T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=MatsudaFrederick en-aut-sei=Matsuda en-aut-mei=Frederick kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=NishinoHaruki en-aut-sei=Nishino en-aut-mei=Haruki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=SiritanasakPraween en-aut-sei=Siritanasak en-aut-mei=Praween kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=SuzukiAritoki en-aut-sei=Suzuki en-aut-mei=Aritoki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=TakakuraSatoru en-aut-sei=Takakura en-aut-mei=Satoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=TomaruTakayuki en-aut-sei=Tomaru en-aut-mei=Takayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= affil-num=1 en-affil=High Energy Accelerator Research Organization, International Center for Quantum-field Measurement Systems for Studies of the Universe and Particles kn-affil= affil-num=2 en-affil=Okayama University, Research Institute for Interdisciplinary Science kn-affil= affil-num=3 en-affil=High Energy Accelerator Research Organization, International Center for Quantum-field Measurement Systems for Studies of the Universe and Particles kn-affil= affil-num=4 en-affil=High Energy Accelerator Research Organization, International Center for Quantum-field Measurement Systems for Studies of the Universe and Particles kn-affil= affil-num=5 en-affil=National Central University, Center for High Energy and High Field Physics, Department of Physics kn-affil= affil-num=6 en-affil=University of California, Department of Physics kn-affil= affil-num=7 en-affil=University of Tokyo, Kavli Institute for the Physics and Mathematics of the Universe kn-affil= affil-num=8 en-affil=University of California, Department of Physics kn-affil= affil-num=9 en-affil=Japan Aerospace Exploration Agency, Institute of Space and Astronautical Science kn-affil= affil-num=10 en-affil=The University of Tokyo, Graduate School of Science, Research Center for the Early Universe kn-affil= affil-num=11 en-affil=National Astronomical Research Institute of Thailand kn-affil= affil-num=12 en-affil=Lawrence Berkeley National Laboratory, Physics Division kn-affil= affil-num=13 en-affil=Kyoto University, Department of Physics, Faculty of Science kn-affil= affil-num=14 en-affil=National Astronomical Observatory of Japan, Gravitational Wave Project Office kn-affil= en-keyword=cosmic microwave background kn-keyword=cosmic microwave background en-keyword=gain calibrator kn-keyword=gain calibrator en-keyword=detector calibration kn-keyword=detector calibration en-keyword=transition edge sensor kn-keyword=transition edge sensor END start-ver=1.4 cd-journal=joma no-vol=13 cd-vols= no-issue=9 article-no= start-page=215 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240823 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A Study of a Drawing Exactness Assessment Method Using Localized Normalized Cross-Correlations in a Portrait Drawing Learning Assistant System en-subtitle= kn-subtitle= en-abstract= kn-abstract=Nowadays, portrait drawing has gained significance in cultivating painting skills and human sentiments. In practice, novices often struggle with this art form without proper guidance from professionals, since they lack understanding of the proportions and structures of facial features. To solve this limitation, we have developed a Portrait Drawing Learning Assistant System (PDLAS) to assist novices in learning portrait drawing. The PDLAS provides auxiliary lines as references for facial features that are extracted by applying OpenPose and OpenCV libraries to a face photo image of the target. A learner can draw a portrait on an iPad using drawing software where the auxiliary lines appear on a different layer to the portrait. However, in the current implementation, the PDLAS does not offer a function to assess the exactness of the drawing result for feedback to the learner. In this paper, we present a drawing exactness assessment method using a Localized Normalized Cross-Correlation (NCC) algorithm in the PDLAS. NCC gives a similarity score between the original face photo and drawing result images by calculating the correlation of the brightness distributions. For precise feedback, the method calculates the NCC for each face component by extracting the bounding box. In addition, in this paper, we improve the auxiliary lines for the nose. For evaluations, we asked students at Okayama University, Japan, to draw portraits using the PDLAS, and applied the proposed method to their drawing results, where the application results validated the effectiveness by suggesting improvements in drawing components. The system usability was also confirmed through a questionnaire with a SUS score. The main finding of this research is that the implementation of the NCC algorithm within the PDLAS significantly enhances the accuracy of novice portrait drawings by providing detailed feedback on specific facial features, proving the system's efficacy in art education and training. en-copyright= kn-copyright= en-aut-name=ZhangYue en-aut-sei=Zhang en-aut-mei=Yue kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KongZitong en-aut-sei=Kong en-aut-mei=Zitong kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HsuChen-Chien en-aut-sei=Hsu en-aut-mei=Chen-Chien kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Graduate School of Environmental, Life, Natural Sciences and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental, Life, Natural Sciences and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Environmental, Life, Natural Sciences and Technology, Okayama University kn-affil= affil-num=4 en-affil=Department of Electrical Engineering, National Taiwan Normal University kn-affil= en-keyword=portrait drawing kn-keyword=portrait drawing en-keyword=auxiliary lines kn-keyword=auxiliary lines en-keyword=OpenPose kn-keyword=OpenPose en-keyword=OpenCV kn-keyword=OpenCV en-keyword=normalized cross-correlation (NCC) kn-keyword=normalized cross-correlation (NCC) en-keyword=exactness assessment kn-keyword=exactness assessment END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue=16 article-no= start-page=1621 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240814 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Postgraduate Year Two Medical Residents' Awareness of Personal Development as a Physician during the Management of Inpatients: A Qualitative Study en-subtitle= kn-subtitle= en-abstract= kn-abstract=Clinical experiences, helping relationships, and reflection are key factors for personal development for physicians. However, few studies have shown which experiences are important for personal growth and how medical residents specifically use their experiences for personal growth. The aim of this study was to identify from the medical residents' perspective which clinical experiences contribute to their personal development. We employed a qualitative design, conducting semi-structured interviews with ten postgraduate year two medical residents at a Japanese teaching hospital. The interviews were transcribed in interview memos, anonymized, and subjected to reflective thematic analysis to generate themes relevant to personal and professional development. Successful clinical experiences with autonomy and responsibility in clinical management were shown to be essential points for personal development as a physician. Autonomy in this study was the attitude of making one's own choices when managing patients. Responsibility was the obligation of the resident to take charge of a patient. Instructing junior trainees, appreciation received from patients, and approval granted by attending physicians reinforced their feelings of personal growth. The realization of what experiences and concepts influence medical residents' personal growth and development will make their professional development more effective. en-copyright= kn-copyright= en-aut-name=TokumasuKazuki en-aut-sei=Tokumasu en-aut-mei=Kazuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ObaraHaruo en-aut-sei=Obara en-aut-mei=Haruo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HirosawaTakanobu en-aut-sei=Hirosawa en-aut-mei=Takanobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OgawaHiroko en-aut-sei=Ogawa en-aut-mei=Hiroko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of General Internal Medicine, Okinawa Chubu Hospital kn-affil= affil-num=3 en-affil=Department of Diagnostic and Generalist Medicine, Dokkyo Medical University kn-affil= affil-num=4 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=autonomy kn-keyword=autonomy en-keyword=personal development kn-keyword=personal development en-keyword=personal growth kn-keyword=personal growth en-keyword=qualitative study kn-keyword=qualitative study en-keyword=responsibility kn-keyword=responsibility END start-ver=1.4 cd-journal=joma no-vol=13 cd-vols= no-issue=16 article-no= start-page=1373 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240817 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Direct Binding of Synaptopodin 2-Like Protein to Alpha-Actinin Contributes to Actin Bundle Formation in Cardiomyocytes en-subtitle= kn-subtitle= en-abstract= kn-abstract=Synaptopodin 2-like protein (SYNPO2L) is localized in the sarcomere of cardiomyocytes and is involved in heart morphogenesis. However, the molecular function of SYNPO2L in the heart is not fully understood. We investigated the interaction of SYNPO2L with sarcomeric alpha-actinin and actin filaments in cultured mouse cardiomyocytes. Immunofluorescence studies showed that SYNPO2L colocalized with alpha-actinin and actin filaments at the Z-discs of the sarcomere. Recombinant SYNPO2La or SYNPO2Lb caused a bundling of the actin filaments in the absence of alpha-actinin and enhanced the alpha-actinin-dependent formation of actin bundles. In addition, high-speed atomic force microscopy revealed that SYNPO2La directly bound to alpha-actinin via its globular ends. The interaction between alpha-actinin and SYNPO2La fixed the movements of the two proteins on the actin filaments. These results strongly suggest that SYNPO2L cooperates with alpha-actinin during actin bundle formation to facilitate sarcomere formation and maintenance. en-copyright= kn-copyright= en-aut-name=YamadaHiroshi en-aut-sei=Yamada en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OsakaHirona en-aut-sei=Osaka en-aut-mei=Hirona kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TatsumiNanami en-aut-sei=Tatsumi en-aut-mei=Nanami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ArakiMiu en-aut-sei=Araki en-aut-mei=Miu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=AbeTadashi en-aut-sei=Abe en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KaiharaKeiko en-aut-sei=Kaihara en-aut-mei=Keiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=TakahashiKen en-aut-sei=Takahashi en-aut-mei=Ken kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TakashimaEizo en-aut-sei=Takashima en-aut-mei=Eizo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=UchihashiTakayuki en-aut-sei=Uchihashi en-aut-mei=Takayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=NaruseKeiji en-aut-sei=Naruse en-aut-mei=Keiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=TakeiKohji en-aut-sei=Takei en-aut-mei=Kohji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= affil-num=1 en-affil=Department of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Science, Nagoya University kn-affil= affil-num=3 en-affil=Department of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=6 en-affil=Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=7 en-affil=Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=8 en-affil=Division of Malaria Research, Proteo-Science Center, Ehime University kn-affil= affil-num=9 en-affil=Graduate School of Science, Nagoya University kn-affil= affil-num=10 en-affil=Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=11 en-affil=Department of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=SYNPO2L kn-keyword=SYNPO2L en-keyword=actinin kn-keyword=actinin en-keyword=actin kn-keyword=actin en-keyword=sarcomere kn-keyword=sarcomere en-keyword=cardiomyocyte kn-keyword=cardiomyocyte END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=16 article-no= start-page=9038 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240820 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Quercetin Attenuates Acetaldehyde-Induced Cytotoxicity via the Heme Oxygenase-1-Dependent Antioxidant Mechanism in Hepatocytes en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is still unclear whether or how quercetin influences the toxic events induced by acetaldehyde in hepatocytes, though quercetin has been reported to mitigate alcohol-induced mouse liver injury. In this study, we evaluated the modulating effect of quercetin on the cytotoxicity induced by acetaldehyde in mouse hepatoma Hepa1c1c7 cells, the frequently used cellular hepatocyte model. The pretreatment with quercetin significantly inhibited the cytotoxicity induced by acetaldehyde. The treatment with quercetin itself had an ability to enhance the total ALDH activity, as well as the ALDH1A1 and ALDH3A1 gene expressions. The acetaldehyde treatment significantly enhanced the intracellular reactive oxygen species (ROS) level, whereas the quercetin pretreatment dose-dependently inhibited it. Accordingly, the treatment with quercetin itself significantly up-regulated the representative intracellular antioxidant-related gene expressions, including heme oxygenase-1 (HO-1), glutamate-cysteine ligase, catalytic subunit (GCLC), and cystine/glutamate exchanger (xCT), that coincided with the enhancement of the total intracellular glutathione (GSH) level. Tin protoporphyrin IX (SNPP), a typical HO-1 inhibitor, restored the quercetin-induced reduction in the intracellular ROS level, whereas buthionine sulphoximine, a representative GSH biosynthesis inhibitor, did not. SNPP also cancelled the quercetin-induced cytoprotection against acetaldehyde. These results suggest that the low-molecular-weight antioxidants produced by the HO-1 enzymatic reaction are mainly attributable to quercetin-induced cytoprotection. en-copyright= kn-copyright= en-aut-name=LiKexin en-aut-sei=Li en-aut-mei=Kexin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KidawaraMinori en-aut-sei=Kidawara en-aut-mei=Minori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ChenQiguang en-aut-sei=Chen en-aut-mei=Qiguang kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MunemasaShintaro en-aut-sei=Munemasa en-aut-mei=Shintaro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MurataYoshiyuki en-aut-sei=Murata en-aut-mei=Yoshiyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NakamuraToshiyuki en-aut-sei=Nakamura en-aut-mei=Toshiyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=NakamuraYoshimasa en-aut-sei=Nakamura en-aut-mei=Yoshimasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=6 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=7 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= en-keyword=quercetin kn-keyword=quercetin en-keyword=acetaldehyde kn-keyword=acetaldehyde en-keyword=glutathione kn-keyword=glutathione en-keyword=aldehyde dehydrogenase kn-keyword=aldehyde dehydrogenase en-keyword=heme oxygenase-1 kn-keyword=heme oxygenase-1 END start-ver=1.4 cd-journal=joma no-vol=137 cd-vols= no-issue=9 article-no= start-page=212 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Mutations in starch BRANCHING ENZYME 2a suppress the traits caused by the loss of ISOAMYLASE1 in barley en-subtitle= kn-subtitle= en-abstract= kn-abstract=The genetic interactions among starch biosynthesis genes can be exploited to alter starch properties, but they remain poorly understood due to the various combinations of mutations to be tested. Here, we isolated two novel barley mutants defective in starch BRANCHING ENZYME 2a (hvbe2a-1 and hvbe2a-2) based on the starch granule (SG) morphology. Both hvbe2a mutants showed elongated SGs in the endosperm and increased resistant starch content. hvbe2a-1 had a base change in HvBE2a gene, substituting the amino acid essential for its enzyme activity, while hvbe2a-2 is completely missing HvBE2a due to a chromosomal deletion. Further genetic crosses with barley isoamylase1 mutants (hvisa1) revealed that both hvbe2a mutations could suppress defects in endosperm caused by hvisa1, such as reduction in starch, increase in phytoglycogen, and changes in the glucan chain length distribution. Remarkably, hvbe2a mutations also transformed the endosperm SG morphology from the compound SG caused by hvisa1 to bimodal simple SGs, resembling that of wild-type barley. The suppressive impact was in competition with floury endosperm 6 mutation (hvflo6), which could enhance the phenotype of hvisa1 in the endosperm. In contrast, the compound SG formation induced by the hvflo6 hvisa1 mutation in pollen was not suppressed by hvbe2a mutations. Our findings provide new insights into genetic interactions in the starch biosynthetic pathway, demonstrating how specific genetic alterations can influence starch properties and SG morphology, with potential applications in cereal breeding for desired starch properties. en-copyright= kn-copyright= en-aut-name=MatsushimaRyo en-aut-sei=Matsushima en-aut-mei=Ryo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HisanoHiroshi en-aut-sei=Hisano en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KimJune-Sik en-aut-sei=Kim en-aut-mei=June-Sik kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=McNellyRose en-aut-sei=McNelly en-aut-mei=Rose kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OitomeNaoko F. en-aut-sei=Oitome en-aut-mei=Naoko F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SeungDavid en-aut-sei=Seung en-aut-mei=David kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=FujitaNaoko en-aut-sei=Fujita en-aut-mei=Naoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=SatoKazuhiro en-aut-sei=Sato en-aut-mei=Kazuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Institute of Plant Science and Resources, Okayama University kn-affil= affil-num=2 en-affil=Institute of Plant Science and Resources, Okayama University kn-affil= affil-num=3 en-affil=Institute of Plant Science and Resources, Okayama University kn-affil= affil-num=4 en-affil=John Innes Centre, Norwich Research Park kn-affil= affil-num=5 en-affil=Department of Biological Production, Akita Prefectural University kn-affil= affil-num=6 en-affil=John Innes Centre, Norwich Research Park kn-affil= affil-num=7 en-affil=Department of Biological Production, Akita Prefectural University kn-affil= affil-num=8 en-affil=Institute of Plant Science and Resources, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=1 article-no= start-page=14543 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240624 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Cervical spinal cord stimulation exerts anti-epileptic effects in a rat model of epileptic seizure through the suppression of CCL2-mediated cascades en-subtitle= kn-subtitle= en-abstract= kn-abstract=Epidural spinal cord stimulation (SCS) is indicated for the treatment of intractable pain and is widely used in clinical practice. In previous basic research, the therapeutic effects of SCS have been demonstrated for epileptic seizure. However, the mechanism has not yet been elucidated. In this study, we investigated the therapeutic effect of SCS and the influence of epileptic seizure. First, SCS in the cervical spine was performed. The rats were divided into four groups: control group and treatment groups with SCS conducted at 2, 50, and 300 Hz frequency. Two days later, convulsions were induced by the intraperitoneal administration of kainic acid, followed by video monitoring to assess seizures. We also evaluated glial cells in the hippocampus by fluorescent immunostaining, electroencephalogram measurements, and inflammatory cytokines such as C-C motif chemokine ligand 2 (CCL2) by quantitative real-time polymerase chain reaction. Seizure frequency and the number of glial cells were significantly lower in the 300 Hz group than in the control group. SCS at 300 Hz decreased gene expression level of CCL2, which induces monocyte migration. SCS has anti-seizure effects by inhibiting CCL2-mediated cascades. The suppression of CCL2 and glial cells may be associated with the suppression of epileptic seizure. en-copyright= kn-copyright= en-aut-name=OkazakiYosuke en-aut-sei=Okazaki en-aut-mei=Yosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SasakiTatsuya en-aut-sei=Sasaki en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HosomotoKakeru en-aut-sei=Hosomoto en-aut-mei=Kakeru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TanimotoShun en-aut-sei=Tanimoto en-aut-mei=Shun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KawaiKoji en-aut-sei=Kawai en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NagaseTakayuki en-aut-sei=Nagase en-aut-mei=Takayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SugaharaChiaki en-aut-sei=Sugahara en-aut-mei=Chiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=YabunoSatoru en-aut-sei=Yabuno en-aut-mei=Satoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KinKyohei en-aut-sei=Kin en-aut-mei=Kyohei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=SasadaSusumu en-aut-sei=Sasada en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=YasuharaTakao en-aut-sei=Yasuhara en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=TanakaShota en-aut-sei=Tanaka en-aut-mei=Shota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=DateIsao en-aut-sei=Date en-aut-mei=Isao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= affil-num=1 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Neurosurgery, Kure Kyosai Hospital kn-affil= affil-num=4 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=10 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=11 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=12 en-affil=Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=13 en-affil=Department of Neurosurgery, Okayama Rosai Hospital kn-affil= en-keyword=Epileptic seizure kn-keyword=Epileptic seizure en-keyword=Glial cells kn-keyword=Glial cells en-keyword=Spinal cord stimulation kn-keyword=Spinal cord stimulation en-keyword=C-C motif chemokine ligand 2 kn-keyword=C-C motif chemokine ligand 2 END start-ver=1.4 cd-journal=joma no-vol=3 cd-vols= no-issue=4 article-no= start-page=583 end-page=595 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231204 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Estimation of the Effects of Achilles Tendon Geometry on the Magnitude and Distribution of Local Strain: A Finite Element Analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=We investigated the influence of Achilles tendon (AT) geometry on local-strain magnitude and distribution during loading, using finite element analysis. We calculated the following eight AT parameters for 18 healthy men: thickness and width of the most distal part, minimum cross-sectional area (mCSA), and most proximal part; length; and position of the mCSA. To investigate the effect of AT geometry on the magnitude and distribution of local strain, we created three-dimensional numerical models by changing the AT parameter values for every one standard deviation (SD) in the range of ±2 SD. A 4000 N lengthening force was applied to the proximal surface of all the models. The mean first principal strain (FPS) was determined every 3% of the length. The highest FPS in each model was mainly observed in the proximal regions; the 86–89% site (the most proximal site was set at 100%) had the highest number of models with the highest FPS (nine models). The highest FPS was observed in the model with a distal thickness of −2 SD, which was 27.1% higher than that of the standard model observed in the 2–5% site. Therefore, the AT geometry influences local-strain magnitude and distribution during loading. en-copyright= kn-copyright= en-aut-name=EnomotoShota en-aut-sei=Enomoto en-aut-mei=Shota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OdaToshiaki en-aut-sei=Oda en-aut-mei=Toshiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Education, Hyogo University of Teacher Education kn-affil= en-keyword=computational model kn-keyword=computational model en-keyword=Mooney-Rivlin model kn-keyword=Mooney-Rivlin model en-keyword=soft tissue kn-keyword=soft tissue END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=裏表紙・英文目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=奥付 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page=79 end-page=89 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=High School Teachers’ Questions and Resource Rooms Teachers’ Explanations during Introductory Stage kn-title=通級による指導の導入期における高校教員の質問と通級担当の説明― 校内体制の整備過程に関する実践報告 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿の目的は，高校における通級による指導の導入期に着目し，校内体制の整備過程に生じた検討課題を明らかにするとともに，それに対する通級担当者による説明の特徴を捉えることであった。第一に，主な検討課題として「導入の是非」「従来の校内組織との関係」「既存の放課後の取組との関係」「従来の単位認定との関係」「障害という要配慮個人情報の取扱い」「通級による指導を生徒が希望していない場合の対応」が生じていた。第二に，通級担当者は，事例校の実情を参考に質問の背景を推測した上で説明を行うという特徴があった。結論として，校内体制の整備を円滑に進めるためには，通級による指導の導入が現在の各高校の取組等にいかなる影響があるのかを明らかにすること，自校にとって望ましい校内体制を模索するために学校の状況を共通理解することの重要性が示唆された。 en-copyright= kn-copyright= en-aut-name=MORIFutoshi en-aut-sei=MORI en-aut-mei=Futoshi kn-aut-name=森太 kn-aut-sei=森 kn-aut-mei=太 aut-affil-num=1 ORCID= en-aut-name=YOSHITOSHIMunehisa en-aut-sei=YOSHITOSHI en-aut-mei=Munehisa kn-aut-name=吉利宗久 kn-aut-sei=吉利 kn-aut-mei=宗久 aut-affil-num=2 ORCID= affil-num=1 en-affil=Doctor’s Course, Joint Graduate School in Science of School Education, Hyogo University of Teacher Education kn-affil=兵庫教育大学大学院連合学校教育学研究科博士課程 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=高等学校 kn-keyword=高等学校 en-keyword=通級による指導 kn-keyword=通級による指導 en-keyword=校内体制 kn-keyword=校内体制 en-keyword=発達障害 kn-keyword=発達障害 en-keyword=特別支援教育 kn-keyword=特別支援教育 END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page=69 end-page=78 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Proposal for Home Economics Class Design That Incorporates Knowledge and Perspective from Other Subjects: From the Characteristics of Home Economics as Seen from Subject Classification and Background Studies kn-title=他教科の知見を取り入れた家庭科授業設計の提案― 教科の分類及び背景学問にみる家庭科の特性から ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿では，教科の分類と歴史的背景から捉えた家庭科教育の位置づけ，背景学問である家政学の特徴に基づき，家庭科という教科の特性や役割について検討し，家庭科の授業設計に対する示唆を得ることを目的とした。
　その結果，他教科の知見を取り入れた家庭科の授業設計の要素として，①自己の生活を再認識する機会を設けること，②他教科から得られた知を取り入れること，③授業展開の中では，自然・社会・人文など諸科学の適切な方法論を取り入れること，④科学知と生活認識をつなげる機会を設けること，⑤他者の生活に対する考え方や見方価値観等を知る機会を設けること，⑥学習したことを踏まえて，自己の生活認識を再構成する機会を設けることの６点が示唆された。 en-copyright= kn-copyright= en-aut-name=TAKUMAChiharu en-aut-sei=TAKUMA en-aut-mei=Chiharu kn-aut-name=詫間千晴 kn-aut-sei=詫間 kn-aut-mei=千晴 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=家庭科教育 kn-keyword=家庭科教育 en-keyword=教科観 kn-keyword=教科観 en-keyword=他教科 kn-keyword=他教科 en-keyword=家政学 kn-keyword=家政学 END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page=51 end-page=67 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Research on ICT-Based Class Development for “Proactive, Interactive, and Authentic Learning” in “Home Economics” at Senior High School (Ⅰ): Developing and Implementing a Lesson on “Why We Need to Plan to Spend Money” kn-title=高等学校「家庭」における主体的・対話的で深い学びを目指すICT を活用した授業開発（Ⅰ）―「 なぜ，金銭を計画的に使う必要があるのか」の開発と実践 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本継続研究では，2016年の知識基盤社会を生きる力の育成を目的とした教育改革において，「社会に開かれた教育課程」の実現のために，授業改善の課題とされた「主体的・対話的で深い学びの実現」と「適切なICT活用による学習活動の充実」に焦点を当て，高等学校普通科目の家庭科において，「主体的・対話的で深い学び」とそれにつながるICT活用の検討による授業開発研究を行い，「主体的・対話的で深い学び」を成立させる授業構成の条件を検討することを目的とした。本稿では，家庭科の「深い学び」に不可欠な家庭経営学習の目的である「自分と金銭との関係」を探究する授業「なぜ，金銭を計画的に使う必要があるのか」の開発と実践結果を中心に報告する。 en-copyright= kn-copyright= en-aut-name=SATOSono en-aut-sei=SATO en-aut-mei=Sono kn-aut-name=佐藤園 kn-aut-sei=佐藤 kn-aut-mei=園 aut-affil-num=1 ORCID= en-aut-name=HASEGAWAChika en-aut-sei=HASEGAWA en-aut-mei=Chika kn-aut-name=長谷川千華 kn-aut-sei=長谷川 kn-aut-mei=千華 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Okayama Mitsu Senior High School kn-affil=岡山県立岡山御津高等学校 en-keyword=家庭科 kn-keyword=家庭科 en-keyword=主体的・対話的で深い学び kn-keyword=主体的・対話的で深い学び en-keyword=ICT kn-keyword=ICT en-keyword=家庭経営学習 kn-keyword=家庭経営学習 en-keyword=高等学校 kn-keyword=高等学校 END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page=43 end-page=50 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Basic Research on the Impact of Children's Creativity on Society II - Organising Issues through a Literature Review on Children's Work - kn-title=子どもの創造性が社会に与える影響についての基礎研究Ⅱ― 子どもの作品に関する文献調査による課題整理 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究の目的は，子どもの創造性と社会とを関連付ける活動を通して，大人が子どもの表現活動に対する新たな価値を獲得するよう促すことである。第一次研究の二つ目にあたる本論では，子どもの作品に関する先行研究から，美術教育における子どもの作品への捉え方について整理する。本調査では，先行研究の調査期間を2008 年から2023 年の16 年間と設定し，美術教育に関する学会誌の三誌に掲載されている研究論文を対象とした。その結果，本調査においては，小学生や未就学児の作品を取り上げる研究が多く，写実表現に向かう中学生や高校生の作品への言及がなされていないことと，子どもの作品自体の「価値を生産」する研究は散見されるものの，「価値を普及」する視点が不足していることがわかった。 en-copyright= kn-copyright= en-aut-name=MATSUURAAi en-aut-sei=MATSUURA en-aut-mei=Ai kn-aut-name=松浦藍 kn-aut-sei=松浦 kn-aut-mei=藍 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=美術教育 kn-keyword=美術教育 en-keyword=子どもの絵 kn-keyword=子どもの絵 en-keyword=表現活動 kn-keyword=表現活動 en-keyword=創造性 kn-keyword=創造性 END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page=35 end-page=42 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Characteristics of Changes in Development of Leadership Theories in the Second Half of the 20th Century: Toward Building a Framework for Global Leadership Education kn-title=20 世紀後半におけるリーダーシップ育成論の変遷の特質― グローバル・リーダー育成のフレーム・ワーク構築を目指して ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究は，20世紀後半におけるリーダーシップ育成理論の変遷をたどりながら，現在のリーダーシップ育成の特質と課題を明らかにしようとするものである。20 世紀後半のリーダーシップ論は，Stogdilの特質論アプローチに始まり，やがて個人の特性ではなく状況に注目した論が展開される。Fiedlerの状況論アプローチは，リーダーが力を発揮できる条件を明らかにした。そして，Burnsの変革型リーダーシップ論が登場する。さらに，Walumbwaのオーセンティック・リーダーシップ論は，リーダーが自分に従う者と信頼できる関係を構築することを重視する理論である。本研究では，状況意識と自己意識という概念を用いて，この変遷を分析した。最後に。以上の考察をふまえて，最後にグローバル・リーダー育成のフレーム・ワーク構築のため示唆について考察した。 en-copyright= kn-copyright= en-aut-name=KUWABARAToshinori en-aut-sei=KUWABARA en-aut-mei=Toshinori kn-aut-name=桑原敏典 kn-aut-sei=桑原 kn-aut-mei=敏典 aut-affil-num=1 ORCID= en-aut-name=GaoYu en-aut-sei=Gao en-aut-mei=Yu kn-aut-name=高雨 kn-aut-sei=高 kn-aut-mei=雨 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Graduate School of Humanities and Social Sciences, Okayama University kn-affil=岡山大学大学院社会文化科学研究科博士後期課程 en-keyword=リーダーシップ kn-keyword=リーダーシップ en-keyword=グローバル・リーダー kn-keyword=グローバル・リーダー en-keyword=状況論 kn-keyword=状況論 END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page=21 end-page=34 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Perspectives Capturing the Dialogue and Zeitlichkeit of Das Sein as Experienced by the Creator in Formative Activities kn-title=制作者が造形表現行為において経験する存在との対話と時間性を捉える視点の研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　This study aimed to develop a perspective that considers the interaction between a creator and the object they create during formative activities as a dialogue, and recognizes it as a means for the creator’s learning. To this end, we conducted a literature survey focusing on Martin Heidegger’s seminal work Sein und Zeit. Through the survey, we could provide examples of learning that creators experience while engaging in dialogue in formative activities. Additionally, we developed a perspective that considers the dialogue related to Das Sein, such as the motifs, impressions, and atmosphere, as linked to the shapes and colors they create. Furthermore, we explored the learning creators acquire as they renew themselves through this dialogic process. en-copyright= kn-copyright= en-aut-name=OHIRAShuya en-aut-sei=OHIRA en-aut-mei=Shuya kn-aut-name=大平修也 kn-aut-sei=大平 kn-aut-mei=修也 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=Formative activity kn-keyword=Formative activity en-keyword=Dialogue kn-keyword=Dialogue en-keyword=Das Sein kn-keyword=Das Sein en-keyword=Zeitlichkeit kn-keyword=Zeitlichkeit en-keyword=Phenomenology kn-keyword=Phenomenology END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page=13 end-page=20 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Career Self-Reliance Orientation and Workplace Retention among Young Workers: Are Career Support Measures a “Double-Edged Sword” ? kn-title=若年就業者におけるキャリア自律の志向性と職場定着― 支援施策は“諸刃の剣”か？ ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　キャリア自律を推進する企業が増えているが，その一方で各種の支援施策が離職や人材流出を招く懸念も指摘されている。本研究では，就業者が抱くキャリア自律の志向性を考慮した分析を行い，キャリア支援施策の活用度と職場定着に関わる心理的変数との関連を検討した。若年就業者255 名のWeb調査への回答の分析から，キャリア支援施策は離職意思の抑制と組織コミットメントの向上という職場定着に有益な効果を持つことが示された。またその効果は，就業者が業界内や専門分野での活躍など広い視野をもつ専門キャリア志向を抱く場合に，より顕著に表れることが示唆された。 en-copyright= kn-copyright= en-aut-name=MISAWARyo en-aut-sei=MISAWA en-aut-mei=Ryo kn-aut-name=三沢良 kn-aut-sei=三沢 kn-aut-mei=良 aut-affil-num=1 ORCID= en-aut-name=KOBAYASHIChinatsu en-aut-sei=KOBAYASHI en-aut-mei=Chinatsu kn-aut-name=小林千夏 kn-aut-sei=小林 kn-aut-mei=千夏 aut-affil-num=2 ORCID= en-aut-name=HASEGAWANaoko en-aut-sei=HASEGAWA en-aut-mei=Naoko kn-aut-name=長谷川尚子 kn-aut-sei=長谷川 kn-aut-mei=尚子 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Okayama Labor Bureau kn-affil=岡山労働局 affil-num=3 en-affil=Faculty of Human Sciences, Department of Psychology, Bunkyo University kn-affil=文教大学人間科学部心理学科 en-keyword=若年就業者 kn-keyword=若年就業者 en-keyword=キャリア自律 kn-keyword=キャリア自律 en-keyword=キャリア支援施策 kn-keyword=キャリア支援施策 en-keyword=職場定着 kn-keyword=職場定着 END