| ID | 54743 |
| フルテキストURL | |
| 著者 |
Takahashi Nobumasa
Department of Paediatrics, Fukuyama Medical Centre
Nojima, Ikuko
Department of Paediatrics, Fukuyama Medical Centre
Araki, Tooru
Department of Paediatrics, Fukuyama Medical Centre
Takasugi, Mizue
Department of Paediatrics, Fukuyama Medical Centre
Sakane, Tomoko
Department of Paediatrics, Fukuyama Medical Centre
Kodera, Aya
Department of Paediatrics, Fukuyama Medical Centre
Ikeda, Masanori
Department of Paediatrics, Fukuyama Medical Centre
Tsukahara, Hirokazu
Department of Paediatrics, Okayama University Hospital
Kaken ID
publons
researchmap
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| 抄録 | Objectives: To compare the diagnostic performance of two norovirus rapid immunochromatographic kits (QuickNavi(®)-Norovirus [QN] and QuickNavi®-Norovirus 2 [QN2]; Denka Seiken, Niigata, Japan) for neonatal and infant faecal specimens.
Methods: Monthly faecal samples were collected from infants from birth to 12 months of age, and tested for norovirus using QN and QN2. Real-time reverse transcription polymerase chain reaction (RT-PCR) was used as the gold standard for norovirus detection. The diagnostic performance of the kits was calculated. Results: A total of 343 specimens from 81 infants were analysed. In all samples, the specificity of QN and QN2 was 80% (275/343) and 99% (339/343), respectively. In infants aged <1 month, the specificity of QN was 33% (23/70), increasing to 93% at 4 months of age. Specificity of QN2 was ≥94% in infants between 0 and 12 months of age. Conclusions: QN2 offers improved performance and is more useful than QN for the diagnosis of norovirus infection in the neonatal and infant period. |
| キーワード | Norovirus
false positive
immunochromatography
neonate
rapid detection test
specificity
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| 発行日 | 2015-09-03
|
| 出版物タイトル |
Journal of International Medical Research
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| 巻 | 43巻
|
| 号 | 5号
|
| 出版者 | Sage
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| 開始ページ | 648
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| 終了ページ | 652
|
| ISSN | 0300-0605
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| NCID | AA00700686
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| 資料タイプ |
学術雑誌論文
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| 言語 |
英語
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| OAI-PMH Set |
岡山大学
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| 論文のバージョン | publisher
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| PubMed ID | |
| DOI | |
| Web of Science KeyUT | |
| 関連URL | isVersionOf https://doi.org/10.1177/0300060515592902
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| Citation | Takahashi N, Nojima I, Araki T, et al. Evaluation of rapid immunochromatographic tests for norovirus in neonatal and infant faecal specimens. J Int Med Res. 2015;43(5):648‐652. doi:10.1177/0300060515592902
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