フルテキストURL fulltext.pdf
著者 Sugihara, Yuusaku| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Morito, Yuki| Takahashi, Sakuma| Harada, Keita| Tanaka, Takehiro| Otsuka, Fumio| Okada, Hiroyuki|
キーワード graft-vs.-host disease terminal ileum allo-hematopoietic stem cell transplantation villous atrophy endoscopy
発行日 2020-02-21
出版物タイトル Experimental and Therapeutic Medicine
19巻
4号
出版者 Spandidos Publications
開始ページ 3076
終了ページ 3080
ISSN 1792-0981
NCID AA12610820
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Sugiharaet al.
論文のバージョン publisher
PubMed ID 32256795
DOI 10.3892/etm.2020.8538
Web of Science KeyUT 000523637100082
関連URL isVersionOf https://doi.org/10.3892/etm.2020.8538
フルテキストURL fulltext.pdf
著者 Hamada, Kenta| Kanzaki, Hiromitsu| Inoue, Masafumi| Ishiyama , Shuhei| Yamauchi, Kenji| Miyahara, Koji| Toyokawa, Tatsuya| Tsuzuki, Takao| Miyaike, Jiro| Matsubara, Minoru| Takahashi, Sakuma| Nishimura, Mamoru| Takenaka, Ryuta| Yunoki, Naoko| Hori, Shinichiro| Kobayashi, Sayo| Yamasaki, Yasushi| Kawahara, Yoshiro| Ishikawa, Hideki| Okada, Hiroyuki|
キーワード anticoagulant agent bleeding endoscopic submucosal dissection gastric cancer heparin replacement warfarin
発行日 2020-11-01
出版物タイトル Internal Medicine
59巻
21号
出版者 The Japanese Society of Internal Medicine
開始ページ 2643
終了ページ 2651
ISSN 0918-2918
NCID AA10827774
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 32641658
DOI 10.2169/internalmedicine.4998-20
Web of Science KeyUT 000589268900003
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.4998-20
フルテキストURL fulltext.pdf
著者 Kinugasa, Hideaki| Hiraoka, Sakiko| Nouso, Kazuhiro| Yamamoto, Shumpei| Hirai, Mami| Terasawa, Hiroyuki| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Yamasaki, Yasushi| Inokuchi, Toshihiro| Takahara, Masahiro| Harada, Keita| Tanaka, Takehiro| Okada, Hiroyuki|
キーワード IBD-associated neoplasia IBD-associated cancer Liquid biopsy ctDNA
発行日 2020-12-03
出版物タイトル BMC Cancer
20巻
1号
出版者 BMC
開始ページ 1188
ISSN 1471-2407
NCID AA12034763
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s). 2020
論文のバージョン publisher
PubMed ID 33272240
DOI 10.1186/s12885-020-07699-z
Web of Science KeyUT 000597268700004
関連URL isVersionOf https://doi.org/10.1186/s12885-020-07699-z
JaLCDOI 10.18926/AMO/60363
フルテキストURL 74_4_265.pdf
著者 Inokuchi, Toshihiro| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahar, Masahiro| Kawano, Seiji| Harada, Keita| Okada, Hiroyuki| Kato, Jun|
抄録 Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy.
キーワード Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-08
74巻
4号
出版者 Okayama University Medical School
開始ページ 265
終了ページ 274
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32843757
Web of Science KeyUT 000562508700001
NAID 120006880202
フルテキストURL SR9_1_11934.pdf
著者 Takahara, Masahiro| Takaki, Akinobu| Hiraoka, Sakiko| Adach, Takuya| Shimomura, Yasuyuki| Matsushita, Hiroshi| Nguyen Tien Thi Thuy| Koike, Kazuko| Ikeda, Airi| Takashima, Shiho| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Sugihara, Yusaku| Harada, Keita| Eikawa, Shingo| Morita, Hidetoshi| Udono, Heiichiro| Okada, Hiroyuki|
発行日 2019-8-15
出版物タイトル Scientific Reports
9巻
出版者 Nature Publishing Group
開始ページ 11934
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2019
論文のバージョン publisher
PubMed ID 31417110
DOI 10.1038/s41598-019-48331-w
Web of Science KeyUT 000480680800048
関連URL isVersionOf https://doi.org/10.1038/s41598-019-48331-w