Acta Medica Okayama 0289-3339 10 4 1993 加齢と運動習慣が換気性閾値に及ぼす影響 482 487 EN No potential conflict of interest relevant to this article was reported.

岡山大学教師教育開発センター Acta Medica Okayama 2186-1323 2 2012 「母校訪問」を核とする全学教職課程初年次プログラムの成果と課題 126 135 EN Daisuke Goto Hiroshi Takahata Takeshi Kashida Tomotaka Mishima Eiji Egi Kayoko Soda Kayo Takahashi Masaru Kaga 10.18926/CTED/48201 岡山大学は全学の教職課程を担う「教師教育開発センター」を平成22年度に創設し、学部の枠を超えた教員養成教育の質保証に取り組んでいる。教育実習事前事後指導や教育実習ならびに教職実践演習（平成25年度から実施）等を中心とする「全学教職コア・カリキュラム」の企画・運営だけではなく、これらの科目の教育成果とその課題を検証し、FD的視点に基づくカリキュラム開発と改善とを進めている。「母校訪問」とは、教育学部以外の学生（文学部、法学部、経済学部、理学部、工学部、環境理工学部、農学部、マッチングプログラムコース）のうち、改正後の教育職員免許法が適用される平成22 年度以降入学生（現１、２年生）を対象に、センターが独自に開発した１年次生対象のプログラムである。本稿ではその成果と課題の検証を通して、いわゆる「開放制」と「大学における教員養成」の原則に基づいた教員養成教育の可能性を検討する。 No potential conflict of interest relevant to this article was reported.

Okayama University Medical School Acta Medica Okayama 0386-300X 33 2 1979 Ultrastructure of rat renal tubular basement membrane--meshwork structure demonstration by negative staining. 133 136 EN Hirofumi Makino Zensuke Ota Yasumasa Takaya Keiko Kida Akira Miyoshi Makoto Hiramatsu Kayo Takahashi Tadashi Ofuji Brief Note 10.18926/AMO/32052 <p>The tubular basement membrane (TBM) (i.e. tubular basal lamina) of rat kidney was shown to be a fine meshwork by electron microscopy after negative staining. Strands of the meshwork formed a regular three dimensional lattice work. The pores of the meshwork were polygonal. There were two main pore sizes: one approximately 30 A in diameter, the other 42--60 A. In view of our previous observation that glomerular and alveolar basement membranes were made up fine meshwork, it is quite possible that the basement membranes of other organs are also made up such fine meshwork.</p> No potential conflict of interest relevant to this article was reported.

Okayama University Medical School Acta Medica Okayama 0386-300X 33 4 1979 Bartter's Syndrome ― Case Report ― 305 314 EN Akira Miyoshi Hirofumi Makino Makoto Hiramatsu Kayo Takahashi Yukio Yamane Jiro Takahara Shinya Suzuki Zensuke Ota Tadashi Ofuji Yoshiaki Takehisa Article 10.18926/AMO/32035 <p>A 26-year-old female with Bartter's syndrome associated with Graves' disease is reported. This patient had a history of Graves' disease from the age of 22 and anti-thyroid drug (Methimazole) had been administered for 2 years. Thyroid function returned to normal but general fatigue and polyuria continued. Hypokalemia was diagnosed at 25 years of age and she was referred to our hospital for evaluation. Blood pressure was normal and laboratory data revealed normal thyroid function, hypokalemic alkalosis, high plasma renin activity and high plasma aldosterone concentration. She showed normal pressor sensitivity to norepinephrine infusion, grossly diminished pressor sensitivity to exogenous angiotensin II infusion compared with the normal. A renal biopsy specimen showed juxtaglomerular cell hyperplasia. Electron microscopy confirmed lacis cell (agranular cell) proliferation.</p> No potential conflict of interest relevant to this article was reported.

Okayama University Medical School Acta Medica Okayama 0386-300X 41 4 1987 Fibrillar ultrastructure of the glomerular basement membrane of the rat kidney as revealed by digestive treatment. 183 185 EN Akira Ichiyasu Michio Takaoka Hirofumi Makino Kayo Takahashi Zensuke Ota Article 10.18926/AMO/31729 <p>Rat kidney glomerular basement membrane (GBM) was isolated and digested with alpha-amylase and elastase. Electron microscopy revealed a meshwork structure composed of fibrils 3 nm in width. They appeared to be type IV collagen fibrils. We succeeded in clarifying a significant ultrastructural aspect of the GBM which had been unclear until now. The findings are consistent with our previously proposed GBM molecular sieve theory.</p> No potential conflict of interest relevant to this article was reported.

Okayama University Medical School Acta Medica Okayama 0386-300X 56 5 2002 Obesity and the risk of diabetes mellitus in middle-aged Japanese men. 255 260 EN Akihiko Seki Tomoko Takigawa Takehiko Ito Etsuko Fukuoka Kayo Takahashi Shohei Kira Article 10.18926/AMO/31704 <p>The morbidity of diabetes mellitus is increasing gradually in Japanese populations. It is important to clarify the risk factors of diabetes in Japanese populations in order to take adequate measures against the increasing morbidity of diabetes. In order to evaluate the link between past and concurrent obesity and diabetes in middle-aged Japanese men, we conducted a worksite-based historical cohort study in Okayama, Japan in 1999. Annual health examination data of middle-aged male workers in a worksite were collected. The relative risks of past and concurrent obesity for developing diabetes were calculated. Subjects with a past history of obesity at between 40 and 50 years of age had a significantly higher risk of developing diabetes by age 55 than did subjects in the normal weight group. These results suggest that, in order to prevent diabetes in middle-aged Japanese men, health guidance for normal weight maintenance should be provided not only for middle-aged men, but also for men under age 40.</p> No potential conflict of interest relevant to this article was reported.

Okayama University Medical School Acta Medica Okayama 0386-300X 31 5 1977 Electron microscopic demonstration of meshwork structure in human and bovine glomerular basement membranes 339 342 EN Zensuke Ota Hirofumi Makino Akira Miyoshi Makoto Hiramatsu Kayo Takahashi Tadashi Ofuji Brief Note 10.18926/AMO/30832 <p>With the electron microscopic and the negative staining method, the glomerular basement membrane of human and bovine kidneys was shown to have a definite fine meshwork structure. The pores of the meshwork of bovine glomerular basement membrane appeared to be pentagonal or hexagonal in shape. Strands of the meshwork branched three-dimensionally and made up the whole basement membrane. The portion of the sgrand between two neighboring branches was presumed to be a structural unit of the basement membrane. Glomerular basement membrane in man showed a structure similar to that seen in cattle, although the pore size of the meshwork was smaller in man than in cattle.</p> No potential conflict of interest relevant to this article was reported.

Okayama University Medical School Acta Medica Okayama 0386-300X 60 2 2006 Assessment of total and segmental body composition in spinal cord-injured athletes in okayama prefecture of Japan. 99 106 EN Yoshihide Inukai Kayo Takahashi Da-Hong Wang Shohei Kira Article 10.18926/AMO/30736 <p>This study assessed total and segmental distribution of fat mass (FM) in athletes with spinal cord injury (SCI) and examined the relationships between segmental distribution of fat mass and age, injury level, athletic history, and training load in order to provide useful information for improvements in their physical strength and training. Twenty-five male athletes with SCI participated in the study. The whole bone composition was measured by a dual-energy X-ray absorptiometry (DXA) method for the calculation of bone minerals, FM, and fat-free mass. The percent fat of the trunk, arms, and legs was also calculated. The percent fat in the legs was highest in comparison with that in the trunk and arms (p &#60; 0.001), and the percent fat in the trunk was higher than that in the arms (p &#60; 0.001). The body fat (p &#60; 0.01), waist circumference (p &#60; 0.01), and waist-to-hip ratio (p &#60; 0.0001) were higher in the group aged 40 or older in comparison with that aged 39 or younger. Path analysis revealed that training load was a factor decreasing the percent fat on the arms and trunk (p &#60; 0.01), and athletic history was a factor reducing the percent fat on the arms (p &#60; 0.05). Our study suggests that exercise is effective in reducing the waist circumference, waist-to-hip ratio, and percent body fat of SCI individuals, and that such effects can help to enhance athletic performance and likely to protect against development of metabolic syndromes resulting from a sedentary lifestyle.</p> No potential conflict of interest relevant to this article was reported.

Okayama University Medical School Acta Medica Okayama 0386-300X 34 1 1980 Changes in the molecular sieve of glomerular basement membrane in rats with aminonucleoside nephrosis. 67 70 EN Yasumasa Takaya Zensuke Ota Hirofumi Makino Keiko Kida Akira Miyoshi Makoto Hiramatsu Kayo Takahashi Tadashi Ofuji Brief Note 10.18926/AMO/30562 Isolated and purified glomerular basement membranes (GBM) of normal and aminonucleoside (PAN) nephrosis rats were observed by electron microscopy after negative staining. Although GBM of normal rats appeared as a molecular sieve with uniform pores, GBM of nephrotic rats showed enlargement and elongation of the pores. For an average of fifty pores, the long dimension was 40.4+/-10.7 A and the short dimension 13.8+/-3.6 A in nephrosis whereas the long dimension was 12.3+/-2.5 A and the short dimension 8.4+/-1.0 A in normal rats. Changes in the pores in GBM were thought to result in increased permeability of serum protein and hence proteinuria. No potential conflict of interest relevant to this article was reported.

岡山医学会 Acta Medica Okayama 0030-1558 95 9-10 1983 原発性腎疾患における抗補体活性の検討 1003 1016 EN Kayo Takahashi The anticomplementary activity (ACA) of the sera of 81 patients with primary glomerular disease was studied. ACA was mesured by a complement consumption test, and the ACA of alternaive pathway was measured by a homolysis inhibition test, using rabbit red blood cells in EGTA buffer. In acute glomerulonephritis, the ACA of the sera with high levels of antistreptokinase and γ-globulin was significantly higher than that of the sera with low levels. The ACA of the sera of sclerosing glomerulonephritis patients was significantly higher than that of the sera of patients in other histlogical categories based on light microscpy. There were no relationships between immunofluorescence findings in the glomerulus and the ACA of the sera of patients with primary glomerular disease. In chronic glomerulonephritis, the ACA of the sera correlated with the levels of BUN, S-creatinine, PSP (15 min.) and Ccr significantly (p<0.001). The sera from uremic patients showed predominantly high ACA and contained heat stable factors (m.w.; more than 25000 daltons) witch were able to activate the classical complement pathway. There observations suggested that the anticomplementary factors in acute glomerulonephritis might be immune complexes and those in uremia might be unknown uremic toxins. No potential conflict of interest relevant to this article was reported.

岡山大学医療技術短期大学部 Acta Medica Okayama 0917-4494 9 1 1998 在宅看護における訪問看護内容の検討 ―病院を基盤とする訪問看護ステーションの事例調査― 23 31 EN Yoshie Sato Kayo Takahashi Toshiko Ikeda Mutsumi Matsueda Kanou Yanagawa 10.18926/15272 病院を基盤とした在宅看護提供機関における在宅看護の現状を調査し,在宅看護の現在の問題点を明らかにするとともに,在宅看護に携わる看護婦の役割について検討した｡本調査の結果,一人暮らしの患者は,家族に介護者のいる患者に比べ明らかにADLが高い場合も訪問看護を受けていることが分かった｡また,高齢者夫婦二人暮らしの患者と2世代以上家族の患者のADLに差はなく,このことは,高齢の介護者に相当の負担がかかっていると言える｡訪問看護内容としては, 日常生活自立度の低い患者への日常生活援助の実施率は高く,精神的支援や指導的看護技術の実施率は低かった｡在宅看護に携わる看護婦は, 日常生活援助に追われがちであるが,一次予防に焦点を当てたケア,患者や介護者の精神的支援,指導,ケアマネジメントを行うことは緊急の課題である｡ No potential conflict of interest relevant to this article was reported.

岡山医学会 Acta Medica Okayama 0030-1558 108 7-8 1996 訪問看護におけるチームケアの取り組み 275 280 EN Kenichi Takai Sachiko Ohta Toshiko Ikeda Misa Miyasato Tetzuzo Kaneshige Takako Kawai Yasumi Haruta Harumi Kitanosako Kayo Takahashi The process of establishing a network between several professions involved in the home care nursing system is reported. This system gave satisfactory support to patients in their home. The frequency of visits by occupational therapists was 45%, 44% for case workers, 44% for visiting nurses from our hospital, 7% for pharmacists, and 3% for dieticians other than doctors and community nurses. For patients residing outside the Okayama Central Hospital areas, the frequency of visits by assistants was 13%, 7% for day care units, and 6% for public health nurses other than doctors and community nurses. Co-operative involvement in the care management of patients was beneficial to the home care nursing system because the needs of patients could be more easily met by members of different professions and opinions from different perspectives improved the quality of patient care. The quality of care management was evaluated and two cases are described. No potential conflict of interest relevant to this article was reported.

岡山大学医療技術短期大学部 Acta Medica Okayama 0917-4494 7 1 1996 腎炎患者の日常生活活動強度 59 66 EN Yoshie Sato Kayo Takahashi Hisao Suzuki Toshiko Ikeda Masuko Kondo 10.18926/11777 腎炎患者の日常生活活動強度と持久性体力を明らかにするため、本研究を行った。被検者は20歳から61歳の腎炎患者7名である。日常生活活動強度の指標として、連続心拍計を用いて24時間心拍数を測定した。また、持久性体力を評価するため、換気性閾値（Ventilatory Threshold : VT）を測定した。各被験者のVTは、同性、同年齢の健常者の値に対する相対値（％VT）で評価した。被検者の％VTの平均は、93.4±18.6％で、健常者に比べて低下していた。24時間心拍数の平均は、82±8拍／分であった。24時間心拍数のうち、VT時の心拍数を越えるものは、多くても2％でしかなく、腎炎患者の日常生活の大部分は、有酸素運動であった。 No potential conflict of interest relevant to this article was reported.

Acta Medica Okayama 1983 原発性腎疾患における抗補体活性の検討 EN No potential conflict of interest relevant to this article was reported.