吉野正

Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17.

フルテキストURL	blood_119_1_285.pdf
著者	Nishimori, Hisakazu\| Maeda, Yoshinobu\| Teshima, Takanori\| Sugiyama, Haruko\| Kobayashi, Koichiro\| Yamasuji, Yoshiko\| Kadohisa, Sachiyo\| Uryu, Hidetaka\| Takeuchi, Kengo\| Tanaka, Takehiro\| Yoshino, Tadashi\| Iwakura, Yoichiro\| Tanimoto, Mitsune\|
備考	This research was originally published in Blood. 2012. © the American Society of Hematology.\|
発行日	2012-01-05
出版物タイトル	Blood
巻	119巻
号	1号
開始ページ	285
終了ページ	295
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン	publisher
PubMed ID	22077062
DOI	10.1182/blood-2011-01-332478
Web of Science KeyUT	000299012400035
関連URL	https://doi.org/10.1182/blood-2011-01-332478

De novo CD5-positive diffuse large B-cell lymphomas show high specificity for cyclin D2 expression

フルテキストURL	K0005304 other1.pdf
著者	Igawa, Takuro\| Sato, Yasuharu\| Takata, Katsuyoshi\| Iwaki, Noriko\| Tanaka, Takehiro\| Asano, Naoko\| Maeda, Yoshinobu\| Orita, Yorihisa\| Nakamura, Naoya\| Nakamura, Shigeo\| Yoshino, Tadashi\|
キーワード	Cyclin D2 CD5 Diffuse large B-cell lymphoma
備考	学位審査副論文\|
発行日	2013-05-15
出版物タイトル	Diagnostic Pathology
巻	8巻
出版者	BioMed Central
開始ページ	81
ISSN	1746-1596
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン	publisher
PubMed ID	23675804
DOI	10.1186/1746-1596-8-81
Web of Science KeyUT	000319266300002
関連URL	https://doi.org/10.1186/1746-1596-8-81 http://ousar.lib.okayama-u.ac.jp/54287

Diagnostic Value of Dual-time-point F-18 FDG PET/CT and Chest CT for the Prediction of Thymic Epithelial Neoplasms

JaLCDOI	10.18926/AMO/54978
フルテキストURL	71_2_105.pdf
著者	Shinya, Takayoshi\| Tanaka, Takashi\| Soh, Junichi\| Matsushita, Toshi\| Sato, Shuhei\| Toyooka, Shinichi\| Yoshino, Tadashi\| Miyoshi, Shinichiro\| Kanazawa, Susumu\|
抄録	We retrospectively assessed the dual-time-point (DTP) F-18 FDG PET/CT findings of thymic epithelial neoplasms (TENs) and investigated the diagnostic capacity of PET/CT compared to that of CT for predicting carcinoma. We calculated the ratio of the standardized uptake value of the tumor and that of the aortic arch (T/M ratio) for both the 90-min early scan and the 2-h delayed scan in 56 TEN patients. We used a multivariate logistic regression (MLR) analysis to estimate the CT features of carcinoma. We compared the diagnostic capacities of PET/CT and chest CT using receiver operating characteristic (ROC) analyses. The ROC curve revealed that the appropriate cut-off T/M ratio value for the highest accuracy was 2.39 with 75.0% accuracy. The area under the curve (AUC) was 0.855. The statistical analyses for DTP scans of 35 TEN patients demonstrated 74.3% accuracy and 0.838 AUC for the early scan versus 82.9% and 0.825 for the delayed scan. The MLR analysis indicated that mediastinal fat infiltration was a predictor of carcinoma. The ROC curve obtained for the model yielded an AUC of 0.853. Delayed scanning could improve the diagnostic capacity for carcinoma. The T/M ratio and mediastinal fat infiltration are predictive of carcinoma with moderate diagnostic accuracy.
キーワード	thymic epithelial neoplasm thymic carcinoma thymoma dual-time-point PET/CT chest CT
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2017-04
巻	71巻
号	2号
出版者	Okayama University Medical School
開始ページ	105
終了ページ	112
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	28420891

Two Relapsed Stage III Childhood Anaplastic Large Cell Lymphoma Patients with NPM-ALK Fusion in Bone Marrow from Initial Diagnosis

JaLCDOI	10.18926/AMO/54815
フルテキストURL	70_6_503.pdf
著者	Kanazawa, Yui\| Yamashita, Yuka\| Fujiwara, Mitsuhiro\| Muraoka, Michiko\| Washio, Kana\| Kanamitsu, Kiichiro\| Ishida, Hisashi\| Nakano, Takae\| Yamada, Miho\| Horibe, Keizo\| Tanaka, Takehiro\| Yoshino, Tadashi\| Shimada, Akira\|
抄録	Childhood anaplastic large cell lymphoma (ALCL) accounts for approx. 10–30 of cases of non-Hodgkin lymphoma, and the ALCL99 study reported 60–75 disease-free survival; however, a relatively high relapse rate was observed (25–30 ). We report 2 patients with Stage III ALCL who relapsed 6–18 months after the end of ALCL99 chemotherapy. A retrospective molecular analysis identified the nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) fusion gene in the first diagnostic bone marrow samples taken from both patients. However, antibodies against the ALK protein appeared to be relatively low in the serum of both patients (×100 and ×750). An increase in chemotherapy intensity may be beneficial if Stage III ALCL patients are shown to be NPM-ALK chimera-positive in the first diagnostic bone marrow sample.
キーワード	ALCL NPM-ALK fusion lymphoma
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2016-12
巻	70巻
号	6号
出版者	Okayama University Medical School
開始ページ	503
終了ページ	506
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	28003677

集学的治療により長期生存が得られた食道神経内分泌癌の2 例

著者	後藤田達洋\| 川野誠司\| 河野吉泰\| 三浦公\| 神崎洋光\| 岩室雅也\| 河原祥朗\| 田中健大\| 吉野正\| 白川靖博\| 田端雅弘\| 谷本光音\| 岡田裕之\|
発行日	2016-12-01
出版物タイトル	岡山医学会雑誌
巻	128巻
号	3号
資料タイプ	学術雑誌論文

拡大内視鏡検査にて形態変化を観察しえた十二指腸濾胞性リンパ腫の1例

タイトル（別表記）	Magnified observation of spontaneous morphological changes of duodenal follicular lymphoma
フルテキストURL	128_111.pdf
著者	岩室雅也\| 高田尚良\| 川野誠司\| 河原祥朗\| 吉野正\| 岡田裕之\|
抄録	A 63-year-old Japanese woman was diagnosed with duodenal follicular lymphoma. The initial esophagogastroduodenoscopic examination with magnifying observation revealed opaque white spots and enlarged whitish villi. Nine months later, esophagogastroduodenoscopy showed that the size of the lymphoma lesion decreased, and only opaque white spots were visible. The histological analysis of biopsy samples obtained during the initial endoscopy examination showed both neoplastic follicles and an inter-follicular infiltration of lymphoma cells, whereas the biopsy samples obtained at the endoscopy performed 9 months later showed only neoplastic follicle formation. These results suggest that the magnifying endoscopic features may reflect the underlying pathological mechanisms : enlarged whitish villi are probably due to lymphoma cell infiltration in the inter-follicular area, and opaque white spots are probably caused by neoplastic follicle formation.
キーワード	消化管原発濾胞性リンパ腫（primary gastrointestinal follicular lymphoma）悪性リンパ腫（malignant lymphoma）拡大内視鏡検査（magnifying endoscopy）
出版物タイトル	岡山医学会雑誌
発行日	2016-08-01
巻	128巻
号	2号
開始ページ	111
終了ページ	116
ISSN	0030-1558
関連URL	isVersionOf https://doi.org/10.4044/joma.128.111
言語	日本語
著作権者	Copyright (c) 2016 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.128.111
NAID	130005262531

Rituximab併用CHOP療法が奏効した肝原発びまん性大細胞型Ｂ細胞リンパ腫の１例

タイトル（別表記）	A primary diffuse large B-cell lymphoma of the liver treated with R-CHOP regimen
フルテキストURL	127_209.pdf
著者	岡田博\| 藤井総一郎\| 渡邉謙太郎\| 重松照伸\| 宮下雄博\| 岡崎守宏\| 小橋春彦\| 横山元浩\| 吉野正\|
抄録	A 78-year-old Japanese man was referred to our hospital after experiencing black feces. No abnormal finding was detected in the endoscopic examination of his stomach and large intestines. Computed tomography (CT) of the abdomen revealed a tumor lesion in the right lobe of the liver. A needle biopsy of the tumor under ultrasound guidance was performed. A pathological examination of the biopsy specimen showed a diffuse proliferation of lymphoma cells, which was compatible with diffuse large B-cell lymphoma (DLBCL). F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)-CT demonstrated increased FDG uptake only in the liver tumor. We made the diagnosis of primary DLBCL of the liver. After six cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP), the patient achieved complete remission and has maintained remission for 2 years since the diagnosis. The R-CHOP regimen might be effective therapy for primary DLBCL of the liver.
キーワード	びまん性大細胞型Ｂ細胞リンパ腫（diffuse large B-cell lymphoma）肝臓（liver） R-CHOP療法（R-CHOP regimen）
出版物タイトル	岡山医学会雑誌
発行日	2015-12-01
巻	127巻
号	3号
開始ページ	209
終了ページ	212
ISSN	0030-1558
関連URL	isVersionOf https://doi.org/10.4044/joma.127.209
言語	日本語
著作権者	Copyright (c) 2015 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.127.209
NAID	130005116809

Primary Duodenal Follicular Lymphoma Treated With Rituximab Monotherapy and Followed-up for 15 Years

JaLCDOI	10.18926/AMO/53676
フルテキストURL	69_5_301.pdf
著者	Seki, Anna\| Iwamuro, Masaya\| Yoshioka, Masao\| Fujii, Nobuharu\| Okada, Hiroyuki\| Nose, Soichiro\| Takata, Katsuyoshi\| Yoshino, Tadashi\| Yamamoto, Kazuhide\|
抄録	A 41-year-old woman was diagnosed with duodenal follicular lymphoma. She had no other lesions and was assigned to a "watch and wait" policy. Swelling of the inguinal lymph nodes appeared 45 months later, and rituximab monotherapy resulted in complete remission. However, follicular lymphoma recurred in the stomach, rectum and mesenteric and external iliac lymph nodes 81 months after the therapy. The patient received rituximab monotherapy again and has remained in complete remission in the fifteenth year after the initial diagnosis. This case suggests the usefulness of rituximab monotherapy in the long-term management of intestinal follicular lymphoma.
キーワード	follicular lymphoma duodenum rituximab
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2015-10
巻	69巻
号	5号
出版者	Okayama University Medical School
開始ページ	301
終了ページ	306
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	26490027
Web of Science KeyUT	000365519600006

A subset of ocular adnexal marginal zone lymphomas may arise in association with IgG4-related disease

著者	Kyotaro, Ohno\| Yasuharu, Sato\| Koh-ichi, Ohshima\| Katsuyoshi, Takata\| Tomoko, Miyata-Takata\| Mai, Takeuchi\| Yuka, Gion\| Tomoyasu, Tachibana\| Yorihisa, Orita\| Toshihiro, Ito\| Steven, H. Swerdlow\| Tadashi, Yoshino\|
発行日	2015
出版物タイトル	Scientific Reports
巻	5巻
資料タイプ	学術雑誌論文

Magnified Endoscopic Features of Duodenal Follicular Lymphoma and Other Whitish Lesions

JaLCDOI	10.18926/AMO/53120
フルテキストURL	69_1_37.pdf
著者	Iwamuro, Masaya\| Okada, Hiroyuki\| Takata, Katsuyoshi\| Kawai, Yoshinari\| Kawano, Seiji\| Nasu, Junichiro\| Kawahara, Yoshiro\| Tanaka, Takehiro\| Yoshino, Tadashi\| Yamamoto, Kazuhide\|
抄録	The sensitivity and specificity of magnified endoscopic features for differentiating follicular lymphoma from other diseases with duodenal whitish lesions have never been investigated. Here we compared the magnified endoscopic features of duodenal follicular lymphoma with those of other whitish lesions. We retrospectively reviewed the cases of patients with follicular lymphoma (n＝9), lymphangiectasia (n＝7), adenoma (n＝10), duodenitis (n＝4), erosion (n＝1), lymphangioma (n＝1), and hyperplastic polyp (n＝1). The magnified features of the nine follicular lymphomas included enlarged villi (n＝8), dilated microvessels (n＝5), and opaque white spots of various sizes (n＝9). The lymphangiectasias showed enlarged villi, dilated microvessels, and white spots, but the sizes of the white spots were relatively homogeneous and their margin was clear. Observation of the adenoma and duodenitis revealed only whitish villi. Although the lymphangioma was indistinguishable from the follicular lymphomas by magnified features, it was easily diagnosed based on the macroscopic morphology. In conclusion, magnified endoscopic features, in combination with macroscopic features, are useful for differentiating follicular lymphomas from other duodenal diseases presenting whitish lesions.
キーワード	duodenal neoplasm follicular lymphoma gastrointestinal lymphoma magnifying endoscopy
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2015-02
巻	69巻
号	1号
出版者	Okayama University Medical School
開始ページ	37
終了ページ	44
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25703169
Web of Science KeyUT	000349740300004

Low-grade B-cell lymphoma presenting primarily in the bone marrow

著者	Iwatani, Kayoko\| Takata, Katsuyoshi\| Sato, Yasuharu\| Miyata-Takata, Tomoko\| Iwaki, Noriko\| Cui, Wei\| Sawada-Kitamura, Seiko\| Sonobe, Hiroshi\| Tamura, Maiko\| Saito, Katsuhiko\| Miyatani, Katsuya\| Yamasaki, Rie\| Yamadori, Ichiro\| Fujii, Nobuharu\| Terasaki, Yasushi\| Maeda, Yoshinobu\| Tanimoto, Mitsune\| Nakamura, Naoya\| Yoshino, Tadashi\|
発行日	2014-07
出版物タイトル	Human Pathology
巻	45巻
号	7号
資料タイプ	学術雑誌論文

Histological and immunohistochemical features of gingival enlargement in a patient with AML

著者	Sonoi, Norihiro\| Soga, Yoshihiko\| Maeda, Hiroshi\| Ichimura, Koichi\| Yoshino, Tadashi\| Aoyama, Kazutoshi\| Fujii, Nobuharu\| Maeda, Yoshinobu\| Tanimoto, Mitsune\| Logan, Richard\| Raber-Durlacher, Judith\| Takashiba, Shogo\|
発行日	2012-07
出版物タイトル	Odontology
巻	100巻
号	2号
資料タイプ	学術雑誌論文

A20 (TNFAIP3) Deletion in Epstein-Barr Virus-Associated Lymphoproliferative Disorders/Lymphomas

著者	Ando, Midori\| Sato, Yasuharu\| Takata, Katsuyoshi\| Nomoto, Junko\| Nakamura, Shigeo\| Ohshima, Koichi\| Takeuchi, Tamotsu\| Orita, Yorihisa\| Kobayashi, Yukio\| Yoshino, Tadashi\|
発行日	2013-02-13
出版物タイトル	PLoS ONE
巻	8巻
号	2号
資料タイプ	学術雑誌論文

In aggressive variants of non-Hodgkin lymphomas, Ezh2 is strongly expressed and polycomb repressive complex PRC1.4 dominates over PRC1.2

著者	Abd Al Kader, Lamia\| Oka, Takashi\| Takata, Katsuyoshi\| Sun, Xu\| Sato, Hiaki\| Murakami, Ichiro\| Toji, Tomohiro\| Manabe, Akihiro\| Kimura, Hiroshi\| Yoshino, Tadashi\|
発行日	2013-11
出版物タイトル	Virchows Archiv
巻	463巻
号	5号
資料タイプ	学術雑誌論文

Distinct morphologic, phenotypic, and clinical-course characteristics of indolent peripheral T-cell lymphoma

著者	Hayashi, Eiko\| Takata, Katsuyoshi\| Sato, Yasuharu\| Tashiro, Yukie\| Tachiyama, Yoshiro\| Sawada-Kitamura, Seiko\| Hiramatsu, Yasushi\| Sugiguchi, Shun\| Nose, Soichiro\| Hirokawa, Mitsuyoshi\| Ando, Midori\| Abd Mader, Lamia\| Maeda, Yoshinobu\| Tanimoto, Mitsune\| Yoshino, Tadashi\|
発行日	2013-09
出版物タイトル	Human Pathology
巻	44巻
号	9号
資料タイプ	学術雑誌論文

Clinicopathologic Analysis of Localized Nasal/Paranasal Diffuse Large B-Cell Lymphoma

著者	Toda, Hiroko\| Sato, Yasuharu\| Takata, Katsuyoshi\| Orita, Yorihisa\| Asano, Naoko\| Yoshino, Tadashi\|
発行日	2013-02-28
出版物タイトル	PLoS ONE
巻	8巻
号	2号
資料タイプ	学術雑誌論文

Large Ulceration of the Oropharynx Induced by Methotrexate-Associated Lymphoproliferative Disorders

JaLCDOI	10.18926/AMO/51072
フルテキストURL	67_4_265.pdf
著者	Hanakawa, Hiroyuki\| Orita, Yorihisa\| Sato, Yasuharu\| Uno, Kinya\| Nishizaki, Kazunori\| Yoshino, Tadashi\|
抄録	We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.
キーワード	ulceration methotrexate oropharynx lymphoproliferative disorders
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2013-08
巻	67巻
号	4号
出版者	Okayama University Medical School
開始ページ	265
終了ページ	269
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	23970326
Web of Science KeyUT	000323470100009

Morphologic, flow cytometric, functional, and molecular analyses of S100B positive lymphocytes, unique cytotoxic lymphocytes containing S100B protein

著者	Miki, Yukari\| Gion, Yuka\| Mukae, Yuriko\| Hayashi, Atsushi\| Sato, Hiaki\| Yoshino, Tadashi\| Takahashi, Kiyoshi\|
発行日	2013-02
出版物タイトル	European Journal of Haematology
巻	90巻
号	2号
資料タイプ	学術雑誌論文

十二指腸濾胞性リンパ腫はAIDの発現を欠くがBACH2の発現を有しmemoryB細胞としての性質を有する

著者	高田尚良\| 佐藤康晴\| 中村直哉\| 徳中摩美\| 三木由香里\| 菊池イアーラ幸江\| 五十嵐和彦\| 伊藤悦郎\| 張替秀雄\| 加藤省一\| 林詠子\| 岡剛史\| 星井嘉信\| 田利晶\| 岡田裕之\| Mohamado, ABD Alkader Lamia\| 前田嘉信\| 谷本光音\| 木下朝博\| 吉野正\|
発行日	2013-08-01
出版物タイトル	岡山医学会雑誌
巻	125巻
号	2号
資料タイプ	学術雑誌論文

外傷性脳傷害に対する抗HMGB-1抗体治療

著者	大熊佑\| 劉克約\| 和気秀徳\| 春間純\| 吉野正\| 大塚愛二\| 高橋英夫\| 森秀治\| 西堀正洋\| 伊達勲\|
発行日	2013-08-01
出版物タイトル	岡山医学会雑誌
巻	125巻
号	2号
資料タイプ	学術雑誌論文

吉野 正