| JaLCDOI |
10.18926/AMO/52789
|
| フルテキストURL |
68_4_235.pdf
|
| 著者 |
Ono, Tetsuichiro|
Shikata, Kenichi|
Obika, Mikako|
Miyatake, Nobuyuki|
Kodera, Ryo|
Hirota, Daisyo|
Wada, Jun|
Kataoka, Hitomi|
Ogawa, Daisuke|
Makino, Hirofumi|
|
| 抄録 |
The aim of this study was to clarify the factors associated with the remission and/or regression of microalbuminuria in Japanese patients with type 2 diabetes mellitus. We retrospectively analyzed the data of 130 patients with type 2 diabetes mellitus with microalbuminuria for 2-6 years (3.39±1.31 years). Remission was defined as improving from microalbuminuria to normoalbuminuria using the albumin/creatinine ratio (ACR), and regression of microalbuminuria was defined as a decrease in ACR of 50% or more from baseline. Progression of microalbuminuria was defined as progressing from microalbuminuria to overt proteinuria during the follow-up period. Among 130 patients with type 2 diabetes mellitus with microalbuminuria, 57 and 13 patients were defined as having remission and regression, respectively, while 26 patients progressed to overt proteinuria. Sex (female), higher HDL cholesterol and lower HbA1c were determinant factors associated with remission/regression of microalbuminuria by logistic regression analysis. Lower systolic blood pressure (SBP) was also correlated with remission/regression, but not at a significant level. These results suggest that proper control of blood glucose, BP and lipid profiles may be associated with remission and/or regression of type 2 diabetes mellitus with microalbuminuria in clinical practice.
|
| キーワード |
microalbuminuria
type 2 diabetes mellitus
remission
regression
|
| Amo Type |
Original Article
|
| 出版物タイトル |
Acta Medica Okayama
|
| 発行日 |
2014-08
|
| 巻 |
68巻
|
| 号 |
4号
|
| 出版者 |
Okayama University Medical School
|
| 開始ページ |
235
|
| 終了ページ |
241
|
| ISSN |
0386-300X
|
| NCID |
AA00508441
|
| 資料タイプ |
学術雑誌論文
|
| 言語 |
英語
|
| 著作権者 |
CopyrightⒸ 2014 by Okayama University Medical School
|
| 論文のバージョン |
publisher
|
| 査読 |
有り
|
| PubMed ID |
25145409
|
| Web of Science KeyUT |
000340687500005
|
| 関連URL |
http://ousar.lib.okayama-u.ac.jp/metadata/52828
|
