start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=929
end-page=942
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Echinostoma hortense ASADA, 1926の生殖細胞染色体と受精に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The adult worms were collected from rats 30 days after infection with metacercariae of Echinostoma hortense which cysted on the gill of Misgurunus anguillicaudatus. The testis and ovaries of matured worms were extracted from live adult worms and there were stained with 45% aceto-orcein solution for chromosome observations. The results of the study are briefly presented as follows.
1. Ten bivalent chromosomes can be seen in both primary spermatocytes and oocytes, which signifies the diploid number of chromosomes to be 20 (2n=20).
2. A spermatocyte is divided into four spertides after binary division.
3. The spermatozac after being transformed into the same number of spermatides, pass through vas deferens and wanter out to the seminal vesicle, and after copulation there, they are ejected into the uterus.
4. When the ovum has moved to the center of ovary, it reaches the leptotene stage and is inseminated.
5. The cocyte after insemination enters into egg-shell at ootype and then migranting towards the uterus, under goes two mitotis (meitotic) division and is transformed to prenucleus.
6. Sperms are gradually enlarged within the oocyte and forming the nucleus, now are transformed to sexual pronucleus. Oocytes that have formed sexual pronucleus in the center of uterus undergo karyogamy near she periphery of uterus, and after the first cleavage of ovum, there are formed two cells of a large and a small one each having 2n=20 chromosomes. Subsequently, they undergo the second cleavage to form one large cell and three small cells. At the time of spawning the ovum is composed of the primary and secondary polocytes and a cell at the fourth cleavage as well as a vitelline cell just before disintegration.
en-copyright=
kn-copyright=

en-aut-name=KusauraTsutomu
en-aut-sei=Kusaura
en-aut-mei=Tsutomu
kn-aut-name=草浦勉
kn-aut-sei=草浦
kn-aut-mei=勉
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部寄生虫学教室
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=871
end-page=880
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=細胞貪食作用の電子顕微鏡的研究 第1編 コロイド粒子の細胞表面への附着現象
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=By using Ehrlich tumor ascites of ddN mice, the phagocytosis of ascites macrophage and the tumor cell has been observed in vitro in the medium containing chondroitin sulfric acidiron colloid.
Observations revealed that macrophage phagocytizes the colloid particles but the tumor cell does not in spite of its marked pinocytotic activity. Macrophage adsorbed the colloid particles on its surface but the tumor cell did not, indicating that the adhesion of the colloid particles induces phagocytosis. At the area where the colloid particles were adsorbed small rhopheocytotic vesicles developed and then phagocytotic vesicles were formed, suggesting that rhopheocytosis is the initial step of phagocytosis. The adsorption of the colloid particles occured on the cell surface with a certain distance but not covering whole the surface of the cell. This fact indicates that specific groups having the affinity to the colloid particle should exist on the cell surface of macrophage, by which macrophage can phagocytize the particles. The particles were found to be accumulated in the phagocytotic vesicles. This should be obtained by the membrane flow toward the inside of the cell. Generally the vesicle is connected to the cell surface by narrow tubule. The number of colloid particles in vesicle will increase with the reduction of vesicular volume by dispersing water and the small molecules into cytoplasm.
en-copyright=
kn-copyright=

en-aut-name=NakatsukaAyako
en-aut-sei=Nakatsuka
en-aut-mei=Ayako
kn-aut-name=中塚綾子
kn-aut-sei=中塚
kn-aut-mei=綾子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一病理学教室
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=827
end-page=836
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=胃炎および胃潰瘍の組織化学的研究 第2編 脱水素酵素について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Whith the use of tissue specimens obtained from 60 patients of stomach polyp, gastritis or gastric ulcer at the time of operation, some histochemical studies on 8 kinds of dehydrogenases, such as SDH, LDH, MDH, alpha-GDH, beta-HDH, G-6-PDH and ICDH were carried out, and the results are briefly summarized in the following.
1. It has been found that the activity of everyone of these dehydrogenases is slightly increased in the tissue of stomach gastritis.
2. In the case of hypertrophic gastritis such activity is still higher.
3. In atrophic gastritis the activity of everyone of these enzymes in gland cells decreases with the decrease in the number of gland cells, but the activity is maintained in proportion to the degree of inflammation.
4. The activity of SDH and NAD-linked dehydrogenases is increased in those encapsulated epithelial cells and gland cells located adjacent to the region of a marked cell infiltration.
5. On the proximal side of the capillary blood vessels in the inflammatory area, the activity of NADP-linked dehydrogenases appears faintly but it is not so noticeable as that of alkalinephosphatase.
6. Among wandering cells, the activity of SDH, LDH and MDH is high in lymphoid cells; the activity of LDH, beta-HDH, G-6-PDH and ICDH is strong in histiocytes; and the activity of SDH and LDH is relatively high in granulocytes.
7. In the neoplasm of the ulcer base, with exception of SDH, everyone of these dehydrogenases shows either a minimal or a moderate activity, but it is somewhat decreased in the region of hyaline degeneration.
8. While the enzyme activity is seen to increase transiently as the necrosis sets in, it decreases with the lapse of time, finally disappearing altogether.
9. The activity of everyone of these enzymes in the regenerated mucous epithelium is found to have increased slightly, and it is stronger than that in the proliferated area of the gastric gland cervix.
10. In those regions of intestinal metaplasia, generally each of these dehydrogenases shows a strong activity, resembling to that in the villi of duodenum.
en-copyright=
kn-copyright=

en-aut-name=TakemotoShigeru
en-aut-sei=Takemoto
en-aut-mei=Shigeru
kn-aut-name=竹本茂
kn-aut-sei=竹本
kn-aut-mei=茂
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第1外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=815
end-page=826
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=胃炎および胃潰瘍の組織化学的研究 第1編 水解酵素について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Using the human stomach tissues resected at the operation for gastric ulcer and gastritis, histochemical studies were carried on five kinds of hydrolysates such as AlP, AcP, beta-Est, AmP and beta-Gl and the following results were obtained.
1. In gastritis the AlP activity in vascular endothelial cells has been observed even in those of the capillary blood vessels of the stomach mucosa.
2. In the case of atrophic gastritis the activity of AcP, beta-Est and beta-Gl are somewhat decreased, while there can be seen no activity of AlP nor of AmP.
3. In hypertrophic gastritis the activity of AcP, beta-Est and beta-Gl in the stomach mucosa is slightly elevated, but there can be observed no activity of AlP and AmP.
4. While there can be observed a marked activity of AlP in the neoplasm at the fundus of gastric ulcer, the activity decreases as there occurs hyaline degeneration, and the regenerated blood capillary vessels in this regenerated area run perpendicularly to the ulcer base. In the stained specimens of these tissues from such a region there can be detected a slight activity of AcP and beta-Gl, but no activity of beta-Est, while that of AmP can be seen occasionally.
5. In the regenerated mucosal gland ducts in the peripheral area of ulcer the activity of AcP, beta-Est and beta-Gl is found to have increased.
6. In the case where the tissue has fallen into a degenerated necrotic state the activity of everyone of these hydrolysates is increased.
7. In the area of intestinal metaplasia, all these enzymes show strong activity, resem-bling that in the villi of duodenum.
8. In those smooth muscles adjacent to inflammatory region, the activity of beta-Est is specifically increased.
9. The activity of AcP and beta-Gl of the epithelial cells in the area with marked cell infiltration is higher than in those epithelial cells located in other regions.
en-copyright=
kn-copyright=

en-aut-name=TakemotoShigeru
en-aut-sei=Takemoto
en-aut-mei=Shigeru
kn-aut-name=竹本茂
kn-aut-sei=竹本
kn-aut-mei=茂
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第1外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=801
end-page=813
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=月経異常患者の尿中17-ketosteroid分画に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Reently, it has been discussed the menstrual disorder caused by deranged metabolism of androgens in ovaries. While the derangement may not be demonstrable by urinary total 17-KS estimation, it is necessary to study urinary 17-KS in detail such as 1) fractionation study of 17-KS, 2) adrenal suppression and gonadal stimulation, dynamic test, after Netter, 3) ratio analysis of specific 17-KS fraction, as androsterone or DHA (dehydoepiandrosterone), to total 17-KS.
The ratio analysis of urinary 17-KS after Yoshida were performed in 32 cases of menstrual disorder and 19 carses of normal female in proliferative phase and dynamic test was combined in 15 cases of menstrual disorder. 1) Specific change in urinary total 17-KS level has not been observed in the cases of menstrual disorder. 2) Urinary 17-KS fractions also did not show specific excretion pattern in these patients. 3) The ratio analysis of androsterone/total 17-KS and DHA/total 17-KS clearly revealed deranged metabolism of androgens in Primary amenorrhea patients. 4) The ratio analysis combined dynamic test demonstrated more clearly the deranged metabolism.
As the conclusion, it should be emphasized that the ratio analysis and the dynamic test were required in evaluating deranged steroid metabolism.
en-copyright=
kn-copyright=

en-aut-name=UnoAkira
en-aut-sei=Uno
en-aut-mei=Akira
kn-aut-name=宇埜昭
kn-aut-sei=宇埜
kn-aut-mei=昭
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部産婦人科
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=789
end-page=799
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=胸腺摘出の免疫能に及ぼす影響に関する実験的研究 特にその血中抗体に及ぼす影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Effects of the thymectomy at birth on immunological function, especially on humoral factor, were studied in mouse. The following results were obtained.
1. Changes in circulating lymphocytes were followed daily for fourty-five days after thymectomy. No increase of lymphocytes was observed in thymectomized mice, although ratio of lymphocytes/neutrophiles increased from two to three during growth in control gronp.
2. Changes in γ-globulin fraction were investigated by paper electrophoresis. No marked difference was found between thymectomized and control groups.
3. Anaphylactic shock was induced after sensitization with egg albumin added with hemophilus pertussis vaccine. There was found no difference in incidence and severity of shock except survival time from onset of shock to death between both groups.
4. The immunological response to foreign tumor transplant was studied using Yoshida and Hirosaki sarcoma of rat. Behavior of growth of tumor cells implanted into peritoneal cavity of mice was investigated.
Three or four days prolongation of survival time of tumor cells was only observed in thymectomized group.
These results show that suppressive effect of thymectomy at birth on immunological function is apparently relating ro cellular antibody, although perticipation of humoral antibody is not completely neglected.
en-copyright=
kn-copyright=

en-aut-name=OkataniTeruta
en-aut-sei=Okatani
en-aut-mei=Teruta
kn-aut-name=岡谷照太
kn-aut-sei=岡谷
kn-aut-mei=照太
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部砂田外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=781
end-page=788
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=膠質粒子の血管壁通過と組織内貯溜に関する研究 第2篇 正常家兎の肝および肝門リンパ節における観察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The deposition and passage of colloidal particles on and across the endothelial wall of sinusoids, their persistence in the parenchyma as well as their transportation to the regional lymph nodes have been studied, after an intravenous injection of a lage amount of India ink and saccharated iron oxide.
The injected colloidal particles are rapidly taken up for the most part by the stellate cells of Kupffer lining the sinusoids and accumlate in their cell bodies, However, a part of colloidal particles are transported to the portal lymph nodes that receive the effluent lymph from the liver, after passing through the intercellular gaps of the sinusoidal endothelium and entering into the lymph stream in the space of Disse.
The chemically stable carbon particles are gradually brough together into large masses formed by coalescence of carbon-laden phagocytes-either stellate cells in the liver or reticular cells in the portal lymph nodes-and persisted for a long time. The colloidal particles of saccharated iron dioxide, on the other hand, appear to be gradually metabolized, after having been phagocytized by either stellate cells in the liver or reticular cells in the portal lymph nodes, and disappear within a month or two. A small amount of carbon particles appear to be taken up by the liver cells during period from 1 to 30 days after the injection.
en-copyright=
kn-copyright=

en-aut-name=MachidaSeizo
en-aut-sei=Machida
en-aut-mei=Seizo
kn-aut-name=町田清三
kn-aut-sei=町田
kn-aut-mei=清三
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一解剖学教室
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=765
end-page=780
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=膠質粒子の血管壁通過と組織内貯溜に関する研究 第1編 正常家兎の骨髄における観察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The passage of colloidal particles across the endothelial wall of sinusoids and their accumulation in the marrow parenchyma have been studied, after an intravenous injection of a large amount of India-ink and saccharated iron oxide.
The injected colloidal particles are first deposited evenly on and in the sinusoidal endothelium within 30 minutes, and then beginn to enter into the marrow parenchyma, passing through the endothelial wall. Thereafter, the colloidal particles are rapidly taken up by the reticular cells in the parenchyma and accumulate in their cell bodies. In these processes of transportation of colloidal particles, the phagocytic activity of both the sinusoidal endothelium and the reticular cells in the marrow parenchyma seem to play a major role.
The chemically stable carbon particles are gradually brought together into large masses formed by coalescence of carbon-laden reticular cells and persist for a long time; whereas the colloidal particles of saccharated iron dioxibe phagocytized by reticular cslls disappear rather rapidly within a month or two, probably having been utilized in the iron metablism of the organism.
en-copyright=
kn-copyright=

en-aut-name=MachidaSeizo
en-aut-sei=Machida
en-aut-mei=Seizo
kn-aut-name=町田清三
kn-aut-sei=町田
kn-aut-mei=清三
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第1解剖学教室
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=949
end-page=954
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Anisakis (Filocapsularia) type幼線虫による肉芽腫の一例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We encoutered a patient suspected of appendicitis. and after the surgical operation we discovered four migrated worms in the submucous tissue of the small intestine. These worms, from their morphology and fine structures of the body, were proven to be larvae of Amsakis (Filocapsularia) type Nematoda.
en-copyright=
kn-copyright=

en-aut-name=InatomiSeiiti
en-aut-sei=Inatomi
en-aut-mei=Seiiti
kn-aut-name=稲臣成一
kn-aut-sei=稲臣
kn-aut-mei=成一
aut-affil-num=1
ORCID=

en-aut-name=ItoYoshihiro
en-aut-sei=Ito
en-aut-mei=Yoshihiro
kn-aut-name=伊藤義博
kn-aut-sei=伊藤
kn-aut-mei=義博
aut-affil-num=2
ORCID=

en-aut-name=SakumotoDaigoro
en-aut-sei=Sakumoto
en-aut-mei=Daigoro
kn-aut-name=作本台五郎
kn-aut-sei=作本
kn-aut-mei=台五郎
aut-affil-num=3
ORCID=

en-aut-name=ItanoKazuo
en-aut-sei=Itano
en-aut-mei=Kazuo
kn-aut-name=板野一男
kn-aut-sei=板野
kn-aut-mei=一男
aut-affil-num=4
ORCID=

en-aut-name=KusauraTutomu
en-aut-sei=Kusaura
en-aut-mei=Tutomu
kn-aut-name=草浦勉
kn-aut-sei=草浦
kn-aut-mei=勉
aut-affil-num=5
ORCID=

en-aut-name=OkahashiKiyoshi
en-aut-sei=Okahashi
en-aut-mei=Kiyoshi
kn-aut-name=岡橋清
kn-aut-sei=岡橋
kn-aut-mei=清
aut-affil-num=6
ORCID=

en-aut-name=KanbaraTakeshi
en-aut-sei=Kanbara
en-aut-mei=Takeshi
kn-aut-name=神原武志
kn-aut-sei=神原
kn-aut-mei=武志
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=7
en-affil=
kn-affil=岡山大学医学部田中外科教室
END

start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=7-9
article-no=
start-page=943
end-page=948
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1966
dt-pub=19660930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=「マアジ」に寄生していた4種幼線虫とAnisakis (Filocapsularia) type幼線虫の形態について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Morphology of four different larvae of Nematodes inclusive of Anisakis type (Filocapsularia) was studied. Larvae were collected from Trachurus japonicus on which they live as parasites. These larvae were classified by the method of Skrjabin et al, and they were found to be larvae of Raphidascaris, Anisakis (Filocapsularia), Contracaecum, and Amplicaecum. Both light and electron microscope observations were carried out with cross-section specimens of these larvae, and it was possible to obtain some characteristic morphological features of the larvae of Anisakis type. Some of these features that differ from those of other larvae are described briefly in the following.
1. The length of larvae of Anisakis type is longest of all the four kinds, and the cross-section of this larva revealed a lateral cord which has a peculiar shape and size.
2. This larva has the thickest cuticle as compared with other three kinds, and the number of muscle cells is most numerous. In addition, the arrangement of the bond of myofibrils is characteristic.
en-copyright=
kn-copyright=

en-aut-name=InatomiSeiiti
en-aut-sei=Inatomi
en-aut-mei=Seiiti
kn-aut-name=稲臣成一
kn-aut-sei=稲臣
kn-aut-mei=成一
aut-affil-num=1
ORCID=

en-aut-name=ItoYoshihiro
en-aut-sei=Ito
en-aut-mei=Yoshihiro
kn-aut-name=伊藤義博
kn-aut-sei=伊藤
kn-aut-mei=義博
aut-affil-num=2
ORCID=

en-aut-name=SakumotoDaigoro
en-aut-sei=Sakumoto
en-aut-mei=Daigoro
kn-aut-name=作本台五郎
kn-aut-sei=作本
kn-aut-mei=台五郎
aut-affil-num=3
ORCID=

en-aut-name=ItanoKazuo
en-aut-sei=Itano
en-aut-mei=Kazuo
kn-aut-name=板野一男
kn-aut-sei=板野
kn-aut-mei=一男
aut-affil-num=4
ORCID=

en-aut-name=KusauraTutomu
en-aut-sei=Kusaura
en-aut-mei=Tutomu
kn-aut-name=草浦勉
kn-aut-sei=草浦
kn-aut-mei=勉
aut-affil-num=5
ORCID=

en-aut-name=OkahashiKiyoshi
en-aut-sei=Okahashi
en-aut-mei=Kiyoshi
kn-aut-name=岡橋清
kn-aut-sei=岡橋
kn-aut-mei=清
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=2
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=3
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=4
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=5
en-affil=
kn-affil=岡山大学医学部寄生虫学教室

affil-num=6
en-affil=
kn-affil=岡山大学医学部寄生虫学教室
END