黄疸鑑別に際してのBSP試験の価値について

BSP retention and serum bilirubin level were determined in cases including 51 of acute hepatitis, 19 of extrahepatic obstructive jaundice and 9 of hepatic cancer with hyperbilirubinemia. The following results were obtained. 1) There was a tendency to show some correlation between BSP and serum bilirubin level in cases of extrahepatic obstructive jaundice. On the contrary, no significant correlation between BSP retention and serum bilirubin level was found in cases of hepatocellular jaundice. 2) Hepatis cancer, showing serum bilirubin level to be approxately 2mg/dl in all cases, exhibited BSP retention at 30min. to be 15 to 30%. 3) there was no significant difference in BSP retentions between hepatocellular jaundice and extrahepatic obstructive jaundice showing same degree of serum bilirubin level in each cases. This indicates that BSP test is not useful for differential diagnosis of these types of jaundice. 4) In the cases with hepatocellular damage, a considerable amount of BSP dye was excreted through the kidney in proportion to its retention in blood.