start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2205 end-page=2220 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Development of the abdominal musculature of Hynobius nebulosus kn-title=霞山椒魚の腹筋の発生に就て en-subtitle= kn-subtitle= en-abstract= kn-abstract=Development of the abdominal musculature of Hynobius nebulosus was studied by dissection under binocular magnifying glass and by serial sections, partly stained with some his tochemical methods, the emphasis being laid oa the origin of the transverse abdominal muscle. Differentiation of the dorsal trunk musculature derived from myotomes is performed in "the dorsal Growth-Zone", and this form of muscle-differentiation is common to that of the ven tral trunc musculature derived from the ventral myotome processes. The internal oblique mescle and the external oblique muscle are derived respectively from the inner and the external la yer of "the ventral Growth-Zone" which appears at the ventrolateral region of the early developed ventral trunk musculature. The former grows ventrally, the latter dorsally from the ventral end of the former. The rectus abdominis muscle is also formed from the veatral end of the "Growth-Zone", and grows medially from the ventral end of both oblique muscles. After the above mentioned muscles have completely differentiated, "the sabvertebral Growth-Zone" appears in the subvertebral triangular region between Chorda and the ventro nedial part of the internal oblique muscle. In this region the subvertebral muscle is formed. At the same time the transverse abdominal muscle d in the narrow space between the internal oblique muscle and Peritoneum, but it is difficult to decide whether the Growth-Zone from which the transverse abdominal muscle is derived belongs to the internal oblique muscle or Peritoneum as the space is very narrow. It mav ba sure that the taaisverse abdominal muscle has closely relation to the internal oblique muscle as both muscles differentiate at the same time. The rectus lateralis muscle dsvelops in "the Growth-Zone in the lateral line" and remaining superficial muscles of trunk also develop superficially on the precedingly differentiated trunk musculature by the same way as above mentioned muscle-differentiation. en-copyright= kn-copyright= en-aut-name=FujimotoToyoaki en-aut-sei=Fujimoto en-aut-mei=Toyoaki kn-aut-name=藤本十四秋 kn-aut-sei=藤本 kn-aut-mei=十四秋 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部解剖学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2195 end-page=2204 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ジギタリス剤使用中長時間心室性頻拍を呈し急性肝萎縮症様症状で死亡した心不全の一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=樋口祥光 kn-aut-sei=樋口 kn-aut-mei=祥光 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=玉尾博康 kn-aut-sei=玉尾 kn-aut-mei=博康 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=戸川淳志 kn-aut-sei=戸川 kn-aut-mei=淳志 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2177 end-page=2183 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=慢性腎炎の腎生検像と機能について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=網岡忠 kn-aut-sei=網岡 kn-aut-mei=忠 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=戸川淳志 kn-aut-sei=戸川 kn-aut-mei=淳志 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2151 end-page=2175 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Studies on the Relation of the Heterogene Reaction in the Serum Protein Precipitation and the Local Anaphylactic Phenomenon kn-title=血清蛋白沈降反応における副反応と局所過敏性現象に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The author examined on the chief and heterogene reaction and the local anaphylactic phenomenon in the antiserum, immunized the rabbit by using the cow serum as the antigen, and obtained the following conclusion. 1. In the antiserum, its antigen is cow serum, there has been seen the specific and the unspecific heterogene precipitation reactions. The unspecific heterogene reaction was most strongest when the goat serum, the closed relation of cow serum, is used; stronger next when guinea pig and horse serums are used; and was in proportion to the frequency of injection. 2. Unspecific heterogene reaction was strong when serum euglobulin and pseudoglobulin are used as antigen and then the specificity of serum albumin was very strong. 3. The local anaphylactic phenomenon on the skin of the sensitizing rabbit by injecting the cow serum, has been seen in case of the goat, horse and guinea pig serums as the heterogene antigen, especially in case of the frequency of immunization. 4. Unspecific local anaphylactic phenomenon was noticed in case of the both antiserum of euglobulin and pseudoglobulin. Antiserum of albumin has species specificity of a higher degree, and showed the unspecific local anaphylactic phenomenon to the goat serum alone, the closed relation for cow serum. en-copyright= kn-copyright= en-aut-name=KusanoSatoru en-aut-sei=Kusano en-aut-mei=Satoru kn-aut-name=草野了 kn-aut-sei=草野 kn-aut-mei=了 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=鹿児島大学医学部法医学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2145 end-page=2150 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An Autopsy Case of Hypoplastic Anemia occurring during the Treatment with Dilantin (Aleviatin) kn-title=Dilantin（Aleviatin）使用中に発症した再生不良性貧血の一剖検例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authors report a case of hypoplastic anemia which suddenly attacked a female, age 23, under the treatment with Dilantin (Aleviatin), an anticonvulsant and drove her to death three weeks after the onset of the disease in spite of various therapies. The chief complaints were a high fever, subcutaneous and gingival bleeding and pharyngealgia. On admission severe hyperchromic anemia, severe leukopenia with lymphocytosis (95%), thrombopenia, hemorrhagic diathesis, angina and typical myelogram were noticed. At autopsy the bone marrow showed hypoplasia and maturation arrest. It is emphasized that the single treatment with Dilantin may produce severe hematopoietic disturbance such as hypoplastic anemia that have not been reported. en-copyright= kn-copyright= en-aut-name=NakagawaShoso en-aut-sei=Nakagawa en-aut-mei=Shoso kn-aut-name=中川昌壮 kn-aut-sei=中川 kn-aut-mei=昌壮 aut-affil-num=1 ORCID= en-aut-name=NishimuraAtsushi en-aut-sei=Nishimura en-aut-mei=Atsushi kn-aut-name=西村惇 kn-aut-sei=西村 kn-aut-mei=惇 aut-affil-num=2 ORCID= en-aut-name=OgoHiroshi en-aut-sei=Ogo en-aut-mei=Hiroshi kn-aut-name=小河博之 kn-aut-sei=小河 kn-aut-mei=博之 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部妹尾病理学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2137 end-page=2144 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Case of Cushing's Syndrom kn-title=Cushing氏症候群の一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authors report a case of Cushing's syndrom with typical clinical pictures, that is, generalized adipositas, full moon face, cutaneous striae, hypertension, osteoporosis, hyperglycemia and excessive secretion of 17-ketosteroid and 17-hydrooxycorticoid. Although the patient had various clinical examination, the primary pathologic site was not found. It might be thought that the site is benign, since no general symptoms became worse during long course. en-copyright= kn-copyright= en-aut-name=WatanabeHaruo en-aut-sei=Watanabe en-aut-mei=Haruo kn-aut-name=渡辺春生 kn-aut-sei=渡辺 kn-aut-mei=春生 aut-affil-num=1 ORCID= en-aut-name=MonobeTaisei en-aut-sei=Monobe en-aut-mei=Taisei kn-aut-name=物部大成 kn-aut-sei=物部 kn-aut-mei=大成 aut-affil-num=2 ORCID= en-aut-name=NakagawaShoso en-aut-sei=Nakagawa en-aut-mei=Shoso kn-aut-name=中川昌壮 kn-aut-sei=中川 kn-aut-mei=昌壮 aut-affil-num=3 ORCID= en-aut-name=ShindoMinoru en-aut-sei=Shindo en-aut-mei=Minoru kn-aut-name=進藤稔 kn-aut-sei=進藤 kn-aut-mei=稔 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2133 end-page=2136 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An Experimental Study on Occult Blood in Feces (Experiment by Oral Administration of Human Blood) kn-title=糞便潜血反応の実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Examinations of occult blood in feces were performed after a certain amount of blood treated previously with hydrochloric acid limonnde was given into the stomach or duodenum through a Levin tube. The follwing results were obtained. 1. All the cases were positive in the reaction after the administration of more than 2 ml. of the blood. 2. No significant difference in the reaction between intragastric and intraduodenal administration. 3. The intensity of the positive reaction became weak as the acidity in gastric juice became high. 4. The longevity of the positive reaction was prolonged with larger amount of the blood given but they were not proportional when the amount of more than 3 ml. of the blood was administrated. After 4 days all the cases showed negative reaction. en-copyright= kn-copyright= en-aut-name=NakagawaShoso en-aut-sei=Nakagawa en-aut-mei=Shoso kn-aut-name=中川昌壮 kn-aut-sei=中川 kn-aut-mei=昌壮 aut-affil-num=1 ORCID= en-aut-name=HiranoYutaka en-aut-sei=Hirano en-aut-mei=Yutaka kn-aut-name=平野寛 kn-aut-sei=平野 kn-aut-mei=寛 aut-affil-num=2 ORCID= en-aut-name=YamamotoYuushi en-aut-sei=Yamamoto en-aut-mei=Yuushi kn-aut-name=山本裕士 kn-aut-sei=山本 kn-aut-mei=裕士 aut-affil-num=3 ORCID= en-aut-name=GotoShoichiro en-aut-sei=Goto en-aut-mei=Shoichiro kn-aut-name=後藤昭一郎 kn-aut-sei=後藤 kn-aut-mei=昭一郎 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2111 end-page=2132 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serological Studies on Aspergillosis Part Ⅳ Studies on prevention of mycosis kn-title=Aspergillosisの血清学的研究 第Ⅳ編 発症防禦に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=As for the treatment of mycosis, there are reported many therapeutical method using antibiotics, chemotherapeutics, vaccine or immune serum; however, there is no report on the basis of prevention of mycosis as yet. The author assumed that the situation might be caused by uncertainity on the mechanism of manifestation of the symptome and that the lung affection, that reported already on the Part Ⅰ of this thesis, was resulted from repeated and large-amounted invasion of the fungus into body. The author studied mass invasion of Aspergillus and found the specific histological change on lung following by 1 or 2 large-amounted inhalation of the fungus to mouse. Also the author observed the preventive effect of the filtrate of the broth into which Asp. oryzae was cultred and the polysaccharide prepared from prepared from pellicle of the organism in the light of the lethality and specific change on tissue. The filtrate and the polysaccharide were given to mouse subcutaneously 1-3 times before the inhalation. en-copyright= kn-copyright= en-aut-name=SeoMasakatsu en-aut-sei=Seo en-aut-mei=Masakatsu kn-aut-name=瀬尾昌克 kn-aut-sei=瀬尾 kn-aut-mei=昌克 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=香川県衛生研究所 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2091 end-page=2109 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serological Studies on Aspergillosis Part Ⅲ Studies on the changes of antigen formed kn-title=Aspergillosisの血清学研究 第Ⅲ編 抗体の消長に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is often pointed out that the immunological reaction turned out sometimes to positive on these who supposed not to he affected from candidiasis or histoplasmosis or turned out in some case to negative on patient. In order to elucidate these facts, the author studied the change on the titer of antigen formed in the light of skin reaction and hemoaggulutination reaction using the sensitized erythrocytes on the pathogene-inoculated rabbit. The change on the titer was noticed on the rabbit which was inoculated the pathogene into the lung through nasal inhalation on the basis of hemoaggulutination reaction; and the titer went down earlier period than the lowering of sensitivity on skin reaction. Hence the hemoaggulutination reaction is said to be more sensitive than the latter. Also it was observed that the skin reaction tock place in different way on rabbit and on man; it was noticed as redness on 24-48 hrs. after the injection on the former while it was noticed as swelling on 3 hrs. after that time on the latter. en-copyright= kn-copyright= en-aut-name=SeoMasakatsu en-aut-sei=Seo en-aut-mei=Masakatsu kn-aut-name=瀬尾昌克 kn-aut-sei=瀬尾 kn-aut-mei=昌克 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=香川県衛生研究所 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2069 end-page=2089 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serological Studies on Aspergillosis Part Ⅱ Serological reactions by purified antigen kn-title=Aspergillosisの血清学的研究 第Ⅱ編 精製抗原による血清反応 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is known that aggulutination reaction is highly informative in examination of mycosis above all candidiasis if the antigen used in the examination is prepared properly and that the antigenic subsatance is contained in polysaccharide obtained from fungous cell. The author already reported the specific hemoaggulutination reaction using the erythrocytes sensitized by Aspergillus with serum of patient or infected rabbit in the Part Ⅰ of this thesis. In this report the hemoaggulutination reaction and skin reaction on rabbit were studied by means of polysaccharide, protein and lipoid, all fractions were obtained from the pellicle of the organism, as antigen. And the author observed that the polysaccharide fraction showed the antigenicity to both reactions mentioned above and that the specificity of the hemoaggulutination reaction to Aspergillus group was also seen by using this polysaccharide antigen. en-copyright= kn-copyright= en-aut-name=SeoMasakatsu en-aut-sei=Seo en-aut-mei=Masakatsu kn-aut-name=瀬尾昌克 kn-aut-sei=瀬尾 kn-aut-mei=昌克 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=香川県衛生研究所 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2049 end-page=2068 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serological Studies on Aspergillosis Part Ⅰ Serological reactical reactions by impure antigen kn-title=Aspergillosisの血清学的研究 第1編 粗抗原による血清反応 en-subtitle= kn-subtitle= en-abstract= kn-abstract=As most of the fungi pathogenic for man are always demonstrable in the natural world, it can not make a diagnosis of mycosis to find a fungus in the secretion or in the excrete of the patient by mycological examinations. Also histological examination is so unpractical because of uneasiness especially in the case of deep mycosis. Thus there are remained only immunological and serological reactions in the diagnosis, still there is not so widely accepted method specific for candidiasis, histopoasmosis or cryptcoccosis. The author observed a lung affection which occured among the emplyees of a chick food factory in Kagawa prefecture in higt prevalence between 1957 and Jum. 1958, and examined all employees in mycological and serological method. The author also studied hemoaggulutination reaction using the erythrocytes sensitized by Asp. oryzae, Asp. fumigatus and a fungous strain isolated from a patient (Takabata Strain) with the serum of employees or of rabbit kept in the factory or inoculated with Asp. oryzae. Observing the higt specificity among the reaction mentioned here, the author supposed this lung affection as lung aspergillosis caused by Asp. flavus-oryzae group. en-copyright= kn-copyright= en-aut-name=SeoMasakatsu en-aut-sei=Seo en-aut-mei=Masakatsu kn-aut-name=瀬尾昌克 kn-aut-sei=瀬尾 kn-aut-mei=昌克 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=香川県衛生研究所 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2035 end-page=2047 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Respiratory Humidity: Efficiency of Humidifiers kn-title=呼吸湿度に関する研究:給湿器の効率について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Adequate humidification of inhaling gases is important for the normal functioning of the respiratory tract. Humidification facilitates expectoration, inhibits the onset of respiratory complications. and prevents them from getting worse. It is especially important in the care of postoperative patients or patients who are under oxygen therapy. There are many types of humidifiers currently being used, but no reports have appeared in the literature on their efficiency. An improved photo tube dew-point hygrometer was used for measuring humidity, which was shown on an electronic recorder automatically and continuously. The temperatures of gases before and after humidification, of water in humidifiers, and of the environment air were measured with thermocouples simultaneusly. A number of experiments were done under varying conditions to evaluate how the efficiency of a bubble-type humidifier is influenced by factors such as: (1) the environment temperature, (2) temperature of gas before it enters the humidifier, (3) temperature of water in it, (4) depth of water for bubbling, (5) number, size and directions of holes from which oxygen-bubbles emanate, (6) flow of oxygen, (7) viscosity of water, etc. The following factors were found to increase the efficiency of humidifiers, experimentally and also theoretically, and were discussed from the standpoint of practical application. (1) Maintaining temperatures of the inlet flow of oxygen, which was the gas used in most cases, and of the water in the humidifier as high as possible. This is the most obvious factor seen from a clinical standpoint. Copper water containers are recommended instead of glass containers, making it possible to maintain the water temperature very close to the environment temperature. The environment should also be kept sufficiently warm. (2) Smaller size and increased number of holes (over ten holes with a diameter of less than 1mm.) can make good humidification, even with high flow. (3) Bubbling through increased water depth (over 10cm. of depth) is recommended. (4) Downward direction of holes is recommended. But, if there are many holes, they should be directed somewhat diverted to lateral so that bubbles radiate in all directions. (5) Increased viscosity of water is not useful for better humidification. Also, the effect of foaming and spraying over the water surface was obserbed. en-copyright= kn-copyright= en-aut-name=SatoToru en-aut-sei=Sato en-aut-mei=Toru kn-aut-name=佐藤暢 kn-aut-sei=佐藤 kn-aut-mei=暢 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=2003 end-page=2016 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cytological Studies on Human Ascites by Means of Vital Staining and Carbon Particle Phagocytosis with Triphenyl Tetrazolium Chloride (T.P.T.) Reaction Part 2. A Study on Tumor Ascites kn-title=生体染色並びに墨粒貪喰による人腹水の細胞学的研究 附T.P.T（Triphenyl Tetrazolium Chloride）反応 第2編 腫瘍性腹水に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=Vital observations were carried on with 33 examples of tumor ascites in tissue culture by means of vital staining and carbon particle phagocytosis and also cytological investigations were conducted with T.P.T reaction. With further studies on the nature and cell composition of ascites the following results were obtained. 1. The average specific gravity of ascites has been found to be 1008-1027, the average protein content 3.36 g/dl., the average cell count 584/㎣, and the composition of cells reveals the increase in the appearance of neutrophils, serous cells and signet ring cells among tumor cell, and these are characteristics of the ascites. By dividing these into two groups, namely one ascites group with the appearance of less than 5 per cent of tumor cells and other with the tumor cell appearance of over 20 per cent, the characteristic traits of ascites might be understood still better. 2. The confirmation of tumor cells and tumorous signet ring cells is taken as a direct indication and cytological peculiarities of other cells are considered to be an indirect indication. 3. As for the direct indication, tumor cells and tumorous signet ring cells are generally stained well with vital staining, and the stainability of the group 2 is better than the group 1. However, that of carbon particle phagocytosis is negative. 4. Cytological peculiarities of their own can be recognized in the vital observations of various cells such as those of adenoma, simple cancer, scirrhus, colloid cancer, hepatoma, coelothelioma. 5. As for the indirect indication, coarse and large granules of various cells can be recognized, and also the acceleration of neutral red staining, phagocytic ability of phagocytes and the appearance of Janus green specific granules as well as enhancement of the neutral red stainability of neutrophils and serous cells can be observed. 6. In T.P.T. reaction tumorous ascites is always positive whereas in other ascites they are negative to this test and therefore, this point proves to be a useful indirect indication. 7. For the distinction between tumorous signet ring cells and phagocytic signet ring cells, both possess their own characteristics of original cells and carbon particle phagocytosis of the former in negative, while the latter is positive. en-copyright= kn-copyright= en-aut-name=KomatsubaraToshishige en-aut-sei=Komatsubara en-aut-mei=Toshishige kn-aut-name=小松原利繁 kn-aut-sei=小松原 kn-aut-mei=利繁 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=1993 end-page=2001 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cytological Studies on Human Ascites by means of Vital Staining and Carbon Particle Phagocytosis Part 1. A Study on Human Non-Pathologic Ascites kn-title=生体染色並びに墨粒貪喰による人腹水の細胞学的研究 第1編 人非病的腹水に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=For the purpose of cytological study of human ascites, the author conducted tissue culture of human non-pathologic ascites and investigated the cell count and the cell composition in the tissue culture by means of vital staining and carbon particle phagocytosis. The following are the results of the present investigations. 1. The average cell count proves to be 1161/㎣ and as for the cell composition definite phagocytes, which can be classified into the large and intermediate and small types, occupy 94.4 per cent of the whole, and it is found that the intermediate and small types occupy the majority in about equal proportion. Other cells such as serous cells, lymphocytes, granulocytes and mast cells can be observed in a small proportion. 2. The large and intermediate type of phagocytes are consisted of cells in such various stages as mature cells to decrepit degenerated cells, and they present variegated findings in vital staining and phagocytosis. However, in these cells the majority of them present scatteringly neutral red granules and carbon black particles in the cell doily but no successive liberation of carbon particles can be observed. 3. Mature cells believed to be the proper form of phagocytes present rosette formation of neutral red granules and the conglomeration of carbon particles within intra-cellular locus and no successive liberation of carbon particles can be observed. Judging from these and other findings (pseudopodial movement and cell morphology) it is suggestive that these cells are cells closely related to monocytes. 4. Although the small type phagocytes demonstrate an extremely poor stainability to neutral red and and a low power of carbon particle phagocytosis and differ somewhat in their morphology as compared to the large and intermediate types, they reveal the characteristics of the above mentioned mature cells. 5. By Janus green staining all the large, intermediate and small types of phagocytes are stained well, and many Janus green granules are found in the perinuclear area as well as in the indentation of the nucleus. en-copyright= kn-copyright= en-aut-name=KomatsubaraToshishige en-aut-sei=Komatsubara en-aut-mei=Toshishige kn-aut-name=小松原利繁 kn-aut-sei=小松原 kn-aut-mei=利繁 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=1939 end-page=1947 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Gerontological Studies, Especially on Epidemiology of Hypertension 4. The Effects of Habits and Surroundings on Blood Pressure kn-title=成人病特に高血圧症の疫学的研究 第4篇 習慣及び環境と血圧との関係について en-subtitle= kn-subtitle= en-abstract= kn-abstract=By investigating the effect of habits and surroundings on the blood pressure (of hypertensives) in Okayama Prefecture, the following results were obtained: 1. There was a close relation between drinking of alcoholic beverage and blood pressure but this concerned with men who acquired the habit of drinking by the force of surroundings. Strong tea and coffee, too, had something to do with blood pressure but in this case the surroundings were out of question. 2. Blood pressure was apt to rise with men who took meals hastily but it bad nothing to do with women. 3. Those who were fond of excessively salty or fatty food often suffered from hypertension. 4. Those who were particular about their food were found in the greatest number among the group of extreme hypertension. 5. Hypertension was rarely found among those with constant poor appetite. 6. Hypertension seldom attacked those who had the following complaints: To fall ill occasionally, to be always out of order, to have severe mental fatigue, to feel fatigue every morning, etc. But hereditary weak constitution had nothing to do with hypertension. 7. The blood pressure rose when the time for sleeting was less than 4 hours. It also rose with those who were easily awakened from their sleep or could not enjoy a sound sleep. But it was difficult to find any immediate relations between the failure to sleep readily or to have regular hours for sleep and the blood pressure. 8. Many heavy smokers were found among hypertensives which shows that smoking is the cause of high blood pressure. 9. The blood pressure rose of women whose household operates less than 50 area of farms while in the household with over one hectares, men's pressure rose. This is because in the former case, the stress of labor falls on women while in the latter, men bear the burden. 10. The rate of grey hair and baldness was high with the group of hypertension irrespective of sex. The same was the case with the declining of memory. en-copyright= kn-copyright= en-aut-name=DateHiroko en-aut-sei=Date en-aut-mei=Hiroko kn-aut-name=伊達寛子 kn-aut-sei=伊達 kn-aut-mei=寛子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=1929 end-page=1937 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Gerontological Studies, Especially on Epidemiology of Hypertension. 3. Investigation of Diseases and Their Subjective Symptoms kn-title=成人病特に高血圧症の疫学的研究 第3篇 自覚症及び疾病の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The subjective symptoms of the aged were studied classifying the patients by their age and blood pressure. And the following results were obtained: 1. The commonest symptom was stiff shoulder and over one half of the subjects had this. And the following symptoms arreared in the order given in their frequency. Fatigability, headache, palpitation, tinnitus, insomnia, numbness, vertigo, stomach repletion, constipation, nycturia, expectoration, caughing, trembling, belching, pyrosis. 2. The following symptoms increased with age: Constipation, numbness, trembling, insomnia, nycturia, tinnitus, caughing. Nycturia and tinnitus were most renarkable. 3. Such symptoms as belching, stomach repletion, pyrosis, fatigability and stiff shoulder decreased with the elevation of blood pressure, fatigability being most remarkable. The symptoms of digestive system came under this categary. 4. The symptoms of respiratory system were more frequent among women, caughing and expectoration being the only symptoms of this categorywhich were found among men. The following symptoms were highly frequent with women: Tinnitns, belching, constipation, numbness: trembling, insomnia, virtigo, palpitation, headache, fatigability, stiff shoulder, stomach repletion, pyrosis, nycturia, etc. Among the above, the frequency of constipation, virtigo, and headache with women was twice of men while that of stiff shoulder, palpitation, belching, numbness, and insomnia was 1.5 times. Such marked subjective symptoms with women may probably due to thier different reactions to the surroundings and their climacterium. 5. The symptoms most frequent with the group with systoric pressure of 180-209 mmHg, were tinnitus, numbness, trembling, palpitation, insomnia, and constipation. These symptoms increased in the group with 180-209 mmHg because the persons in this group were in the period when the blood pressure fluctuates sharply while it dropped with the group with over 210 mmHg as their blood pressure was stabilized. 6. It was found the disease and sex difference were two important factors for causing subjective symptoms. en-copyright= kn-copyright= en-aut-name=DateHiroko en-aut-sei=Date en-aut-mei=Hiroko kn-aut-name=伊達寛子 kn-aut-sei=伊達 kn-aut-mei=寛子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=1919 end-page=1927 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Gerontological Studies, Especially on Epidemiology of Hypertension 2. Electrocardiographic Studies kn-title=成人病特に高血圧症の疫学的研究 第2篇 心電図学的検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The relations between their electrocardiographic findings and their age, sex, ophthalmoscopic findings and blood pressure were studied on 531 persons in Okayama Prefecture, and the follwing results were obtained: 1. Abnormal electrocardiograms inceased with their age, blood pressure and the aggravation of ophthalmoscopic findings. 2. Arthmias such as premature beat and myocardidial infarction were more frequent with hypertensives and those of advanced age. Bundle branch block and auricularfibrillation were also frequent with those of advanced age. 3. As for the change of P wave, left auricolar hypertrophy was more frequent with those of advanced age. 4. Both in relation to their blood pressure and age, the left type with horizontal position of the electrical sxis predominated. This position was especially large in number with women beiween 40-60 years probably because of their physique. 5. Left ventricular hypertrophy and myocardial injury increased with the elevation of blood pressure, age and the aggravation of ophthalmoscopic findings. 6. It seems that the electrocardiograms of the aged persons were affected by such factors as their age and the blood pressure which had been rising previously. en-copyright= kn-copyright= en-aut-name=DateHiroko en-aut-sei=Date en-aut-mei=Hiroko kn-aut-name=伊達寛子 kn-aut-sei=伊達 kn-aut-mei=寛子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=1909 end-page=1917 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Gerontological Studies, Especially on Epidemiology of Hypertension. 1. Investigation of Blood Pressure kn-title=成人病特に高血圧症の疫学的研究 第1篇 血圧に関する検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Mainly on the cardiovascular system of 1,175 persons were studied for a period from 1957 to 1958. The subjects were divided into two groups of normotensive and hypertensive ones. The latter group was further sub-divided into mild, moderte and severe ones. (They were examined clinically and) The following results were obtained: 1. In the group whose systolic pressure was 150-179 mmHg and the group of 180-209 mmHg, it was found that the hypertensives who had the above ranging pressure markedly increased between the ages of 40 and 60. The mild hypertension predominated among women while the moderate and severe ones among men. 2. Heredity had much to do wich the hypertension of young peodle and its effect was more remarkable among the cases of severe hypertension. The relations between heredity and hypertension were not clear with the aged people. 3. The sclerosis of the radial artery was low among the hypertensives, and it was rather high among women. 4. Regarding albuminuria. the rate of positivity increased with blood pressure and it was highest with the moderate hypertension group. 3.2% of all subjects revealed to be positive sugar in the urine and the rate of positivity increased with the blood pressure. Moreover it was closely related to the elevation of diastric pressure. No relation was discovered between the positivity of urinary urobilinogen and the blood pressure. 5. The ophthalmoscopic findings aggravated with the persons in thier sixties and about one half of that group registered as K. W. Ⅱ degrees. But it was rather better with those in their seventies. This indicated that those with unfavorable ophthalmoscopic findings mostly die in thier sixties. 6. 23.3% of those whose ophthalmoscopic findings registered as K. W. Ⅲ degrees had albuminuria. 7. With the aggravation of ophthalmoscopic findings, the sclerosis of radial artery increased. en-copyright= kn-copyright= en-aut-name=DateHiroko en-aut-sei=Date en-aut-mei=Hiroko kn-aut-name=伊達寛子 kn-aut-sei=伊達 kn-aut-mei=寛子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=1901 end-page=1908 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Case of W-P-W Syndrome with Paroxysmal Auricular Fibrillation kn-title=心房細動発作を伴つたWPW症候群の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=38-year-old male who had paroxysmal atrial fibrillation which was electrocardiograpm-cally very mimic to ventricular tachycardia was studied. This case was also confirmed as having ventricular septal defect (Roger's disease) by means of chest roentgenograms, right heart catheterization and phonocardiogram. Some considerations on the causes, etiology, complications and therapy of this type of arrhythmia were made. en-copyright= kn-copyright= en-aut-name=SuezawaYasuko en-aut-sei=Suezawa en-aut-mei=Yasuko kn-aut-name=末沢泰子 kn-aut-sei=末沢 kn-aut-mei=泰子 aut-affil-num=1 ORCID= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=11-12 article-no= start-page=1893 end-page=1899 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Two Cases of Complete Atrioventricular Block kn-title=房室完全ブロックの2例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Two cases of complete atrioventricular block due to hypertensive cardiovascular disease were studied. The one was 68-year-old male in whom complete atrioventricular block with automaticity of His's bundle and ventricle was noted. The other was 81-year-old male in whom complete atrioventricular block with ventricular capture was noted. Some considerations on the causes and clinical manifestations of complete atrioventricular block were made. en-copyright= kn-copyright= en-aut-name=SuezawaYasuko en-aut-sei=Suezawa en-aut-mei=Yasuko kn-aut-name=末沢泰子 kn-aut-sei=末沢 kn-aut-mei=泰子 aut-affil-num=1 ORCID= en-aut-name=IshidaHidemasa en-aut-sei=Ishida en-aut-mei=Hidemasa kn-aut-name=石田秀雅 kn-aut-sei=石田 kn-aut-mei=秀雅 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=大阪医科大学病理学教室 END