start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1969 end-page=1988 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Electrophysiological Study on the Pallidofugal Fibers as the Conduction System of Epileptic Discharges kn-title=癲癇痙攣伝導路としての遠淡蒼球線維に関する生理学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this study, the auther has attempt to study electrophysiologically the aspect of pallidofugal fibers which are intermediated by the pallidum to the fibers arising from the motor area as the conduction system of epileptic discharge. Action potentials of motor cortex, basal ganglia, nuclei of the midbrain and spinal cord were recorded during major convulsive or subclinical seizures which are elicited by local administration of metrazol to the motor cortex or the thalamus of dogs. For subcortical recordings, a pair of bipor needle electrodes made of steel wire, mapproximately 200 μ in diameter on tungsten microelectrodes approximately 20 μ in diameter at the tip were used. Both steel and tungsten electrodes insulated by baking enamel except the tip. Spike discharges (duration of each spike is 20-60 msec. amplitude 50-100 μV recorded by abovementioned electrodes) are accounted for the epileptic discharges in this study. The results were as follows: 1) There are two different pathways transmitting the discharges from the motor area to the pallidum, one is direct connection between the motor cortex to the pallidum and the other has some relays the nuclei, thalamus and caudate nucleus, between them. These different pathways are connected separately to two different pallidofugal fiber group at the pallidum. 2) The pallidofugal fiber group, which is connected to the former pathways at the pallidum, are relayed at the contralateral substantia nigra and then terminated to anterior horn cells of the spinal cord. There is a fiber crossing to the other side at the midbrain between the pallidum and substantia nigra. 3) The pallidofugal fiber group connected to the latter at the pallidum does not show crossing to the other side on its course to the homolateral substantia nigra. But the downward fibers from the substantia nigra show a crossing to the other side at the pons and terminate in the contralateral anterior horn cells. en-copyright= kn-copyright= en-aut-name=FujiiShinichiro en-aut-sei=Fujii en-aut-mei=Shinichiro kn-aut-name=藤井愼一郎 kn-aut-sei=藤井 kn-aut-mei=愼一郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第1外科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1959 end-page=1968 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Iron Metabolism in Hookworm Disease by means of Radioactive Iron (Fe(59)) Administration Part 3. Effects of the Injection of Hookworm Disease Sera upon the Iron Metabolism kn-title=放射性鉄による鉤虫症の鉄代謝に関する研究 第3編 鉤虫症血清注射の鉄代謝に及ぼす影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=By oral administration of radioactive iron, Fe(59), to the rabbits injected with the serum of patient with hookworm disease or with the serum of dogs with hookworms as well as to the rebbits (the control) injected with sera of normal person or of normal dogs, the author studied the effects of toxin in the sera of hookworm disease upon the iron metabolism. As the results it has been found that the rate of iron absorption in the rabbits injected with the sera of hookworm disease is lower than that in the control, and in these test animals the rate of iron being taken into erythrocytes is also low. Fe(59) tends to be distributed more in the liver and spleen, at the same time the iron contents in organs show a tendency of increasing. This tendency is exactly identical with the results observed in the rabbits injected with hookworm emulsion (Part 2), proving that the toxin in the serum of hookworm disease is also involved in the interferance with the absorption and mobilization of iron as the case of toxin of the body of hookworm. en-copyright= kn-copyright= en-aut-name=UetsukaKaoru en-aut-sei=Uetsuka en-aut-mei=Kaoru kn-aut-name=上塚香 kn-aut-sei=上塚 kn-aut-mei=香 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1949 end-page=1958 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Iron Metabolism in Hookworm Disease by means of Radioactive Iron (Fe(59)) Administration Part 2. Effects of the Injection of Hookworm Emulsion on the Iron Metabolism kn-title=放射性鉄による鉤虫症の鉄代謝に関する研究 第2編 鉤虫乳剤注射の鉄代謝に及ぼす影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=After the oral administration of radioactive iron, Fe(59), to the rabbits injected with emulsion of hookworms from human or dogs and to normal rabbits (control), the author investigated the effects of toxin of the hookworm body on the iron metabolism. As the results the rabbits injected with hookworm emulsion show the lower rate of absorption by the digestive tract and up-take of the absorbed Fe(59) to erythrocytes when compared with the control, and Fe(59) tends to be distributed more in the liver, spleen and bone marrow. At the same time the iron contents in organs show a tendency of an increase as compared with the control. From these findings it appears that toxin in the body of hookworm plays an important role in the disturbances of the absorption and mobilization of iron. In addition, the author conducted similar experiments on the rabbits with chronic anemia by blood depletion and on the rabbits with benzol anemia and compared their results. en-copyright= kn-copyright= en-aut-name=UetsukaKaoru en-aut-sei=Uetsuka en-aut-mei=Kaoru kn-aut-name=上塚香 kn-aut-sei=上塚 kn-aut-mei=香 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1937 end-page=1948 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Iron Metabolism in Hookworm Disease by means of Radioactve Iron (Fe(59)) Administration Part 1. The Iron Metabolism in Dogs with Hookworm Disease kn-title=放射性鉄による鉤虫症の鉄代謝に関する研究 第1編 鉤虫犬の鉄代謝について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Using dogs such as ones spontaneously infected with hookworms, ones dewormed of these hookworms, those experimentally infected with hookworms showing marked intestinal hemorrhage as well as normal dogs (the control), and orally administering them radioactive iron, Fe(59), the author determined the radioactive iron in erythrocytes and plasm periodically. Then 48 hours later perfusion is given and fractionating the visceral iron by Yoneyama-Konno's method, the iron contents and Fe(59) are estimated. As the results, it has been found that the iron-absorption rate is lowest in the dogs spontaneously infected with hookworms, followed in an ascending order of normal dogs and dewormed dogs, and highest in the dogs with experimental hookworm disease. As for the distribution of Fe(59) absorbed, in the spontaneously infected dogs it is distributed mostly in the liver, spleen and bone marrow, demonstrating an extremely low portion of it taken into erythrocytes. In the dewormed dogs, on the contrary, the major portion of the absorbed Fe(59) is taken up by erythrocytes and it is sparsely distributed in the liver, spleen and bone marrow, and this tendency is still more marked in the dogs with experimental hookworm disease, Furthermore, the iron contents of various organs in the dogs spontaneously infected with hookworms, though slightly less than in the normal, are greater than those found in the dewormed dogs, proving a marked decrease in the dogs with experimental hookworm disease. From these data it is assumed that there is a definite impediment to the absorption and mobilization of iron in hookworm disease and that such an impediment together with hemorrhage induce anemia. en-copyright= kn-copyright= en-aut-name=UetsukaKaoru en-aut-sei=Uetsuka en-aut-mei=Kaoru kn-aut-name=上塚香 kn-aut-sei=上塚 kn-aut-mei=香 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1929 end-page=1936 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Experimental Studies on the Changes by Death, of the Vegetative Plankton (Diatoms) in the Organs of Drowned Bodies Report Ⅲ The Experimental Studies on the Changes by Death, of the Vegetative Plankton (Diatoms) in the Organs of Drowne Bodies at Winter kn-title=溺死体臓器における植物性Plankton珪藻の死後における消長に関する実験的研究 第Ⅲ編 冬季における溺死体臓器における植物性Plankton珪藻の死後における消長について en-subtitle= kn-subtitle= en-abstract= kn-abstract=The author has had an experiment on the changes by death, of the vegetative Plankton (diatoms) in the organs of drowned bodies at winter, and has acquired the following results: 1) There were the 11 Diatoms were found in the water of the river used for this exepriment. 2) Most Diatoms were found in the lung and femur even two months after death but in the heart, liver and kidney in which each organs became softon, found the Diatoms only one month after death. Even after treating those organs, just a few Diatoms could be found. 3) Among 11 Diatoms, Cymbells parva, Melosira islandica and Cyclotella comta were considered in the strength for resisting to decomposition; and it was Tabellaria fenestrata which was not found at the earliest time. en-copyright= kn-copyright= en-aut-name=ShiragamiKiyotoshi en-aut-sei=Shiragami en-aut-mei=Kiyotoshi kn-aut-name=白神清敏 kn-aut-sei=白神 kn-aut-mei=清敏 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部法医学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1921 end-page=1927 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cytochemical Studies on the Mitochondria of Blood Cells Part 4. Cytochemical Study on the Mitochondria of Blood Cells with the Electron Microscope kn-title=血球ミトコンドリアの細胞化学的研究 第4編 血球ミトコンドリアの細胞化学的電子顕微鏡的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In order to elucidate the microstructures of the mitochondria in blood cells in the relation with the sites of enzyme activities the author carried out electron microscopic observations on the ultra-thin sectioned specimens prepared from the normal blood cells on which the cytochemical reaction of the respiratory enzyme system has been made with the use of potassium tellurite, a heavy metal salt. As the result, it has been verified that the terminal respiratory enzyme system is localized mainly in mitochondria, and that these are significant differences in the enzyme activity of mitochondria not only between those belonging to the different kind of blood cells but also even in those found in a cell. It has also been demonstrated that these enzymes are found as a farily dense contiguous mass mainly locating in the cristae of mitochondrion, and some in the mitochondrial membrane. These observations show that there are some differences in the enzyme activity between the membrane and the cristae of mitochondria. en-copyright= kn-copyright= en-aut-name=SakaiAkira en-aut-sei=Sakai en-aut-mei=Akira kn-aut-name=酒井晃 kn-aut-sei=酒井 kn-aut-mei=晃 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1909 end-page=1913 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cytochemical Studies on the Mitochondria of Blood Cells Part 2. Cytochemical Study on the Cytochrome Oxidase System kn-title=血球ミトコンドリアの細胞化学的研究 第2編 血球のチトクローム酸化酵素系に関する細胞化学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is difficult to make an accurate cytochemical demonstration of the cytochrome oxidase system in the mitochondria of blood cells by the conventional Nadi reaction. By applying the Oda's method for the cytochemical, detection of cytochrome c-cytochrome oxidase system and cytochrome c oxdase the author succeeded in demonstrating cytochemically the cytochrome c oxidase or the cytochrome c-cytochrome oxidase system in the mitochondria of blood cells by using p-phenylenediamine as substrate and neotetrazolium salt as hydrogen acceptor with or without the addition of cytochrome c. This reaction appears in the cytoplasm of all blood cells with an exception of mature erythrocytes in the form of distinct violet-colored round or rod-like granules coinciding with mitochondria. The number, distribution and the grades of the enzyme activity of mitochondria can be seen. whose pictures are specific to each call species. Maturation and differentiation of cells generally proceed with the decrease both in number and enzyme activity. en-copyright= kn-copyright= en-aut-name=SakaiAkira en-aut-sei=Sakai en-aut-mei=Akira kn-aut-name=酒井晃 kn-aut-sei=酒井 kn-aut-mei=晃 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1897 end-page=1907 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cytochemical Studies on the Mitochondria of Blood Cells Part 1. Cytochemical Study on the Succinic Dehydrogenase System of Blood Cells kn-title=血球ミトコンドリアの細胞化学的研究 第1編 血球のコハク酸脱水素酵素系に関する細胞化学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In the field of hematology the supravital staining by Janus green has been used extensively for counting of the number of mitochondria of leucocytes. But it has been clarified that all the mitochondria can not be stained by this method. With the purpose to establish a method to stain all mitochondria the author has scrutinized the histochemical method for the respiratory system, especially the succinic dehydrogenase system, localizing solely in mitochondria and devised the color reaction to appear coinciding fairly exactly at the site of mitochondria improving the past method. For the enzyme reactions sodium succinate was used as the substrate and neotetrazolium chloride, nitro-neotetrazolium chloride or nitiro-blue tetrazolium chloride as the hyrogen acceptor. In this paper by the applicatiou of this method the author stuied the correlation between the site and intensity of the reaction in each cell species with reference to the differentiation and maturation. The results are as follows: 1. The cytochemical reaction of this enzyme appears positive in all blood cells with exception of mature erythrocytes. This enzyme reaction decreases its intensity along with the maturation and differentiation of cells. 2. The enzyme reaction appears specifically coinciding with the site of mitochondria in cells including reticulocytes. 3. This enzyme reaction is extremely useful for counting the number of mitochondria in blood cells as well as for ascertaining their enzymatic activity. en-copyright= kn-copyright= en-aut-name=SakaiAkira en-aut-sei=Sakai en-aut-mei=Akira kn-aut-name=酒井晃 kn-aut-sei=酒井 kn-aut-mei=晃 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1879 end-page=1896 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Serum- and Organ-Phosphatase, and its Production Part Ⅱ. Influences of Carbon Tetrachloride, Ligation of the Choledochus and Reticulo-endothelial System (R. E. S.) Blocking upon Serum- and Organ-Phosphatse kn-title=血清および臓器Phosphataseの研究並びにPhosphatase産生について 第2編 四塩化炭素,胆管結紮,網内系塡塞の血清並びに臓器Phosphataseに及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Phosphatases in serum and organs (the liver, adrenal gland, spleen, kidney, jejunum and the bone marrow) were estimated biochemically after subcutaneous injection of CCl(4), ligation of the choledochus and R. E. S. blocking by India ink, obtaing following results. 1) Following injection of CCl(4) the phosphatases in serum were increased temporarily and later decreased markedly, but alkali phosphatase became below the level of which before injection. Also in the rabbits ligated the choledochus those, especially alkali phosphatase, were remarkably increased, and decreased in R. E. S. blocking. 2) After injection of CCl(4) alkali phosphatse was decreased in the liver with no changes in the acid phosphatase, and no changes were observed in the liver after ligation of the choledohhus. 3) From the facts obtained in 1) and 2), it is concluded that phosphatases (at least alkali phosphatase) were produced in the liver. 4) In the R. E. S. blocking alkali phosphatase was remarkably decreased in the liver, spleen and the bone marrow. This indicates that the R. E. S. plays an important role on the phosphatase, in cooporation with decrease of acid and alkali-phosphatase in the serum. 5) Phosphatases in the adrenal gland have shown no changes by those procedures. 6) Phosphatases in the kidney were not changed by those procedures, with only exception of decrease in alkali phosphatase after ligation of the choledochus. 7) Alkali phosphatase in the jejunum was decreasd after injection of CCl(4) or ligation of the choledochus, and increased after R. E. S. blocking. 8) The spleen is related to the storage of phosphatase and has a regulation effect. 9) Acid phosphatase in the bone marrow was tended to increase after injection of CCl(4) or ligation of the choledochus, and alkali phosphatase was decreased after blocking of R. E. S. en-copyright= kn-copyright= en-aut-name=KonishiHitoshi en-aut-sei=Konishi en-aut-mei=Hitoshi kn-aut-name=小西等 kn-aut-sei=小西 kn-aut-mei=等 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第2外科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1865 end-page=1878 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Serum-and Organ Phosphatase, and its Production Part Ⅰ. Influences of the Cancer Tissue Extract on Serum-aad Organ-Phosphatase kn-title=血清および臓器Phosphataseの研究並びにPhosphatase産生について 第1編 癌組織抽出液の血清並びに臓器Phosphataseに及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Phosphatases in serum and organs (the liver, adrenal gland, spleen, jejunum and the bone marrow) were estimated biochemically after injection of the cancer tissue extract into rabbits, and following results were obtained. 1) Following injection of cancer extract serum phosphatases were decreased, though, alkali phosphatase was slightly increased only when the toxic effect was severe. 2) In the organs of normal rabbits alkali phosphatase was larger in amount than acid phosphatase, excepting only the adrenal gland in reverse. Acid phosphatse was largest in amount in the jejunum, subsequently the spleen, adrenal gland, kidney, liver and the bone marrow. Alkali phosphatse was also largest in the jejunum, subsequently the kidney, spleen, liver, bone marrow and the adrenal gland. 3) Influences of injection of the cancer extract on the phosphatases in organs were as follows: The liver; alkali phosphatse was increased but no changes in acid phosphatse. The adrenal gland; alkali phosphatse was increased but no changes in acid phosphatse. The spleen, no changes in the phosphatses were observed. The kidney; decreases in both phosphatases were seen. The je junum; decreases in both, especially marked in alkali phosphatase. The bone marrow; no changes were observed, though, alkali phosphatase was slightly increased when the toxic effect was severe. 4) It was surmised that an intimate relation between the liver and the phosphatase was present. en-copyright= kn-copyright= en-aut-name=KonishiHitoshi en-aut-sei=Konishi en-aut-mei=Hitoshi kn-aut-name=小西等 kn-aut-sei=小西 kn-aut-mei=等 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1857 end-page=1864 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cytologycal Studies on the Mechanism Inducing Allergic Inflammation Part 3. The Electronmicroscopic Observation on the peritoneal Monocytes from the Sensitized Rabbits after Exposing to Antigen kn-title=アレルギー性炎発現の機構に関する細胞学的研究 第3編 感作家兎腹腔単球に対する抗原の作用に関する電子顕微鏡的観察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The change occurring at the time when antigen it acting on the peritoneal monocytes in the rabbits sensitized with bovine serum was observed under an electronmicroscope. By the action of antigen monocytes become swollen and devoid of pseudopodia, at the same time mitochondria also swell up and cristae ase destroyed. Likewise endoplasmic reticulum swelling up, grow indistinct. Moreover, when antigen is made to act on the supra-vitally stained cells, in the case of Neutral Red there is no significant difference in the cell picture from that of cells receiving no supra-vital staining. As has previously been clarified, since Neutral Red is the substance existing in the cell as the dye droplets showing no affinity to the any one of cell organellae, the dispersion of dye particles seem to be due to the destruction of endoplasmic reticulum, which is supposed to keep the dye as droplets. Janus Green has been proved to have a special affinity to mitochondria, and in the cells previously stained supra-vitally when they come in contact with antigen, their mitochondria do not expand as much as in the case of unstained cells, but the cells show a marked agglomeration of cytoplasm. This seems to be due to the concomitant acceleration in the affinity of Janus Green to organellae other than mitochondria, and also due to the changes in molecular arrangement in the cell at the time of the swelling of endoplasmic reticulum. en-copyright= kn-copyright= en-aut-name=HayashiHiroshi en-aut-sei=Hayashi en-aut-mei=Hiroshi kn-aut-name=林弘 kn-aut-sei=林 kn-aut-mei=弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1849 end-page=1855 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cytological Studies on the Mechanism Inducing Allergic Inflammation Part 2. The Permeability of the Cell Membrane of Peritoneal Monocytes, with a Special Reference to the Changes after Antigen Action kn-title=アレルギー性炎発現の機構に関する細胞学的研究 第2編 腹腔単球の細胞膜透過性について殊に抗原作用後の変化 en-subtitle= kn-subtitle= en-abstract= kn-abstract=As reported in the previous paper in the belief that tha acceleration of the cell-membrane permeability and the resultant inflow of external-fluid into the cell are responsible for the dispersion of vital-staining dye particles within the cell when the antigen is made to act on peritoneal monocytes from the rabbits sensitized with bovine serum, the author estimated the fluctuation in the permeability of Janus green and Nile blue both before and after the action of antigen. In this series of experiments the author employed the conventional supra-vital staining combined with the method for the fixation of the dye by potassium mercuric iodide solution devised by Seno, Haba, Maki et al. and estimated the changes in the permeability under a microspectrophotometer. As the result, it has been verified that cells coming in contact with antigen increase in the cell-diameter by about 2.5μ and the permeability for dyes is accelerated 1.71 to 2.22 times in one minute. en-copyright= kn-copyright= en-aut-name=HayashiHiroshi en-aut-sei=Hayashi en-aut-mei=Hiroshi kn-aut-name=林弘 kn-aut-sei=林 kn-aut-mei=弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1839 end-page=1847 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cytological Studies on the Mechanism Inducing Allergic Inflammation Part 1. A Study on the Reaction of the Peritoneal Monocytes from the Sensitized Rabbits to the Antigen kn-title=アレルギー性炎発現の機構に関する細胞学的研究 第1編 牛血清感作家兎の腹腔単球の抗原との接触反応について en-subtitle= kn-subtitle= en-abstract= kn-abstract=The fact that the degradiation products evolving out of cell destruction in the local tissue are the factors playing an important role in a series of exsudative phenomena called as the inflammatory reaction is well-known as already reported by Menkin and others. It is difficult to distinguish the primary disturbance caused by inflammation-inducing substances from the secondary disturbance due to the products of tissue disintegration, but it may be possible to learn the manner of the inflammation-inducing cell destruction if the action of the inflammation inducing substances is so swift that the cells can be observed prior to the onset of the secondary reaction. From these viewpoints the author selected allergic inflammation as the subject for study, and first of all with the use of a phasecontrast microscope pursued the changes caused by the action of antigen on those free cells not being in inflammatory situation. When antigen is made to act on the peritoneal monocytes of the rabbits sensitized with bovine serum the cells quickly retract their pseudopodia; cells become swollen; the nuclear membrane becomes distinct and the nuclear and cytoplasmic structures become indistinct. In addition, when supra vitally-stained cells are observed, they change the shapes rapidly, and the dye, losing its granular form, spread very quickly and extensively in the cytoplasma. These phenomena seem to suggest the acceleration of permeability due to the destruction of the cell membrane with resultant flow of external fluid into the cell, a rapid change in molecular arrangement within the cell, and the demolition of the cell itself due to the activation of various catabolic enzymes, and the emigration of disintegrated substances to the outside of the cell. en-copyright= kn-copyright= en-aut-name=HayashiHiroshi en-aut-sei=Hayashi en-aut-mei=Hiroshi kn-aut-name=林弘 kn-aut-sei=林 kn-aut-mei=弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1835 end-page=1838 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study on Fixation of Vitamin B(2) and Liver Glycogen kn-title=ビタミンB(2)と肝臓糖源の定固について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Using rats, the author experimented the influence of the refined Vitamin B(2) upon the fixation of liver glycogen and obtained the following results. 1) On the lack of Vitamin, all quantity of glycogen in liver decreased. 2) The quantity of glycogen in liver increased by the injection of Vitamin B(2). 3) From the results mentioned above, Vitamin B(2) is one of causes to make a good influence upon the fixation of liver glycogen. en-copyright= kn-copyright= en-aut-name=MatsumotoMasuo en-aut-sei=Matsumoto en-aut-mei=Masuo kn-aut-name=松本増夫 kn-aut-sei=松本 kn-aut-mei=増夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山医科大学第1内科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1827 end-page=1834 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Influence of Vitamin B(2) and C Upon the Absorption of Several Kinds of Monosaccharide to the Intestinal Canal Part 2 The Influence of Vitamin C Upon the Absorption of Several Kinds of Monosaccharide to the Intestinal Canal kn-title=ビタミンB(2)およびCの各種単糖類の腸管内吸収におよぼす影響について 第2編 ビタミンCの各種単糖類の腸管内吸収におよぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The author had the experiment infusing the several kinds of monosaccharide (glucose, xylose and galactose) to the intestinal canals of rats, and investigating the influence of Vitamin C upon the absorption of monosaccharide, and obtained the following results. 1) The injection of the proper quantity of Vitamin C was effective for the absorption of glucose to the intestinal canal, but the much injection did reduce the index of absorption. 2) The same action was seen at the absorption of galactose. 3) The injection of the proper quantity of Vitamin C had no influence upon the absorption of xylose. This can be said because the absorption of xylose (pentose) is difference with that of hexose as glucose, galactose and etc. en-copyright= kn-copyright= en-aut-name=MatsumotoMasuo en-aut-sei=Matsumoto en-aut-mei=Masuo kn-aut-name=松本増夫 kn-aut-sei=松本 kn-aut-mei=増夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山医科大学第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1819 end-page=1826 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Influence of Vitamin B(2) and C Upon the Absorption of Several Kinds of Monosaccharide to the Intestinal Canal Part 1 The Influence of Vitamin B(2) Upon the Absorption of Several Kinds of Monosaccharide to the Intestinal Canal kn-title=ビタミンB(2)およびCの各種単糖類の膓管内吸収におよぼす影響について 第1編 ビタミンB(2)の各種単糖類の腸管内吸収におよぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The author had the experiment infusing the several kinds of monosaccharide (glucose, xylose and galactose) to the intestinal canals of rats and investigating the influence of Vitamin B(2) upon the absorption of monosaccharide and obtained the following results: 1) The young animals have increased their weight by the injection of the proper quantity of Vitamin B(2). In this case, the rate of increase was proportionated to the quantity of injected Vitamin B(2). 2) Owing to the injection of the proper quantity of Vitamin B(2), the absorption index of glucose to the rat's intestinal canal became to rise. In this case, the rising rate was proportionated to the quantity of the injected Vitamin B(2). 3) Owing to the injection of the proper quantity of Vitamin B(2), the absorption index of galactose to the rat's intestinal canal became to rise. In this case, the rising rate was proportionated to the quantity of the injected Vitamin B(2). 4) The absorption index of xylose to the intestinal canal has no relation with the injection of Vitamin B(2). This can be said because the absorption of xylose (pentose) is difference with that of hexose as glucose, galactose and etc. en-copyright= kn-copyright= en-aut-name=MatsumotoMasuo en-aut-sei=Matsumoto en-aut-mei=Masuo kn-aut-name=松本増夫 kn-aut-sei=松本 kn-aut-mei=増夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山医科大学第1内科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1809 end-page=1818 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on serum and brain water content of cats with latent local cerebral anaphylaxis. (LLCA) Part 2. The brain Water Content and Electroencephalography in Ctas with Latent Local Cerebral Anaphylaxis kn-title=潜在性脳局所アナフィラキシー猫(実験的癲癇症)における血清学的研究,ならびに脳含水量について 第2編 潜在性脳局所アナフィラキシー猫(実験的癲癇症)の脳含水量と脳波 en-subtitle= kn-subtitle= en-abstract= kn-abstract=LLAC were produced experimentally by injecting inactive bovine serum as antigen in cats. During 300 days after the last effective injection, brain water content of cats with LLCA was measured and their EEG was recorded. 1) The water content in the motor cortex of cat with LLCA tends to increase during a considerable period as 60 days after the last effective injection. This increasing is the edema type which mainly dues to that of free water. About half of this edema type shows an electroencephalographically dominant slow wave more markedly than the normal. 2) In cats with LLCA the stadium in which the title of antibody shows maximum and in which γ-globulin increases accordes with the existing time of brain edema. The antibody remains much longer. The increase of water content in the brain tissue is regarded to provocate or accerlate the convulsion. Therefore we can prove from the stand point of water metabolism in the berain tissue that the cats with LLCA is xperimentally disposed to convulsion. en-copyright= kn-copyright= en-aut-name=MiyatakeShozaburo en-aut-sei=Miyatake en-aut-mei=Shozaburo kn-aut-name=宮武昭三郎 kn-aut-sei=宮武 kn-aut-mei=昭三郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第1(陣内)外科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1793 end-page=1807 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on serum and brain water content of cats with latent local cerebral anaphylaxis.(LLCA) Part 1. Anaphylactic antibody and Electrophoretic Fraction of Serum Protein in Cats with Latent Local Cerebral Anaphylaxis kn-title=潜在性腦局所アナフィラキシー猫(実験的癲癇症)における血清学的研究,ならびに腦含水量について 第1編 潜在性脳局所アナフィラキシー猫(実験的癲癇症)における過敏症抗体と血清蛋白分屑の変動に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The cats with latent local cerebral anaphylaxis were produced by injecting inactive bovine serum antigen. During 300 days after the last effective injection, anaphylactic antibody in the blood and electrophoretic fraction of serum protein were investigated by precipitin reaction and the use of Tiselius apparatus. 1) The title of antibody stays at maximum meanly during 60 days after the last effective injection and then gradually decreases. After 120 days it descends markedly. But even after a considerable period of time as 300 bays it still can be proved. 2) The ups and downs of total protein and globulin shows a parallel relation with that of γ-globulin. Their increase is regarded to owe to that of γ-globulin. No difinite relation is seen between the ups and downs of protein, α-globulin and γ-globulin. 3) The ups and downs of the title of antibody and that of γ-globulin were compared. The latter shows a tendency of an earlier descending than the former but generally they have a parallel relation. In the latent local cerebral anaphylactic cats the abnormal irritability of brain nerve cells especially the descending threshold of cardiazol seizure has been proved by many works done in our institute. In such cats the title of antibody is high, can be kept during a long time and also the increase of γ-globulin is seen. This fact can be proof that cats with LLCA is disposed to convulsion by any stimulation. en-copyright= kn-copyright= en-aut-name=MiyatakeShozaburo en-aut-sei=Miyatake en-aut-mei=Shozaburo kn-aut-name=宮武昭三郎 kn-aut-sei=宮武 kn-aut-mei=昭三郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第1(陣内)外科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1785 end-page=1792 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Lighting by Fluorescent Lamp The Influence of the moving colored objects upon near point kn-title=螢光灯による人工照明―各種色彩の移動視標が眼近点距離に及ぼす影響― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Fluorescent lamp was compared with incadescent lamp concerning the influence upon the shift of the near point after the task seeing the rotating objects with colored stripes. The apparatus is shown in Fig. 1. The drum is covered by paper with stripes of white and one of the standard colors is used by Japanese Color Institution (black, red, yellow and green). Each stripe has the width of 3 cm and an angle of 45° to its moving direction. It rotates at the speed of 60 times per minute. Each examinee has to see this object through a window of 4×5cm opened in the midst of black carton paper, from the distance of 30cm for 20minutes. During the examination he is requested to number the stripes in order to fix his attention to this visual activity. Examinees were men and women of 19-33 years old, with normal vision and without any ophthalmological defect. Mazda Daylight Fluorescent Lamp (FI-200, 20 watt) and Mazda Gas-filled Lamp (100 volt, 100 watt) were used for the examination. The near point optometer by Dr. Ishihara was used for the measurement of near point. The results were as follows: 1) In the illumination of 200 lux, the near point shifts much further in fluorescent lighting than in incadescent lighting. This is true in every color. 2) In fluorescent lighting black and red are more effective than yellow and green. In incadescent lighting no distinguishable difference can be seen among the colors. 3) The examinee feels more comfortable by the case of incadescent lighting than fluorescent lighting. Yellow is the best and green follows in his subjective feeling. From the above results, the authors conclude that incadescent lighting is better than fluorescent lighting when we are engaged in works to see moving objects. en-copyright= kn-copyright= en-aut-name=MochizukiYoshio en-aut-sei=Mochizuki en-aut-mei=Yoshio kn-aut-name=望月義夫 kn-aut-sei=望月 kn-aut-mei=義夫 aut-affil-num=1 ORCID= en-aut-name=NasuShozo en-aut-sei=Nasu en-aut-mei=Shozo kn-aut-name=那須昭三 kn-aut-sei=那須 kn-aut-mei=昭三 aut-affil-num=2 ORCID= en-aut-name=KurodaTakeshi en-aut-sei=Kuroda en-aut-mei=Takeshi kn-aut-name=黒田健 kn-aut-sei=黒田 kn-aut-mei=健 aut-affil-num=3 ORCID= en-aut-name=OkahiraKazuma en-aut-sei=Okahira en-aut-mei=Kazuma kn-aut-name=岡平和磨 kn-aut-sei=岡平 kn-aut-mei=和磨 aut-affil-num=4 ORCID= en-aut-name=MurakamiSadao en-aut-sei=Murakami en-aut-mei=Sadao kn-aut-name=村上貞夫 kn-aut-sei=村上 kn-aut-mei=貞夫 aut-affil-num=5 ORCID= en-aut-name=HigashiwaraRyoei en-aut-sei=Higashiwara en-aut-mei=Ryoei kn-aut-name=東原良頴 kn-aut-sei=東原 kn-aut-mei=良頴 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部衛生学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部衛生学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部衛生学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部衛生学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部衛生学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1781 end-page=1784 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Oxidation of G-6-P, 6-P-G and R-5-P in the Epileptic Cerebral Cortex kn-title=眞正癲癇大脳皮質によるGlucose-6-phosphate, 6-PhosphogulconateおよびRibose-5-phosphateの酸化について en-subtitle= kn-subtitle= en-abstract= kn-abstract=The oxidations of G-6-P, 6-P-G and R-5-P in the human epileptic cerebral cortex were measured by Warburg's manometer and compared with those of non-epileptic cerebral cortex. The results were as follows: 1) The oxidation of G-6-P, 6-P-G and R-5-P in epileptic cerebral cortex, showed stronger tendency to be controlled than that of the non-epileptic. 2) The oxidation of G-6-P and 6-P-G were more accerelated by the addition of TPN in both cases, and then the difference of oxidation in the each cases of epileptic and non-epileptic cerebral cortex became less. 3) From the facts mentioned above, it is considered that the shunt pathway of glucose metabolism, i. e. Warburg-Dickens scheme, exists in the brain also as in the liver. en-copyright= kn-copyright= en-aut-name=OnodaOsamu en-aut-sei=Onoda en-aut-mei=Osamu kn-aut-name=小野田収 kn-aut-sei=小野田 kn-aut-mei=収 aut-affil-num=1 ORCID= en-aut-name=AsahinaMasaru en-aut-sei=Asahina en-aut-mei=Masaru kn-aut-name=朝比奈勝 kn-aut-sei=朝比奈 kn-aut-mei=勝 aut-affil-num=2 ORCID= en-aut-name=NishiharaYohichi en-aut-sei=Nishihara en-aut-mei=Yohichi kn-aut-name=西原庸一 kn-aut-sei=西原 kn-aut-mei=庸一 aut-affil-num=3 ORCID= en-aut-name=TanakaYoshinori en-aut-sei=Tanaka en-aut-mei=Yoshinori kn-aut-name=田中美登 kn-aut-sei=田中 kn-aut-mei=美登 aut-affil-num=4 ORCID= en-aut-name=MoriAkitane en-aut-sei=Mori en-aut-mei=Akitane kn-aut-name=森昭胤 kn-aut-sei=森 kn-aut-mei=昭胤 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一外科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一外科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一外科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一外科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1771 end-page=1780 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on Stored Blood Part 2. Ill effects of transfusion by stored hemolyzed blood kn-title=保存血に関する研究 第2編 保存溶血々液輸血の副作用に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=1. After the transfusion by fresh hemolyzed blood the animal become feverish, but after that with stored hemolyzed blood almost no fever is seen. 2. In case of transfusion with fresh hemolyzed blood, a descending of blood pressure is found but in that with stored hemolyzed blood it is not found. 3. After transfusion with fresh or stored blood a temporary decrease of nonprotein nitrogen is seen. It is especially marked after that with stored hemolyzed blood. 4. After transfusion with fresh hemolyzed blood the serum A/G decreases but γ-globulin increases. After that with stored hemolyzed blood the latter decreases rather weakly. 5. In the histological findings aftes transfusion with fresh or stored hemolyzed blood, in the kidney nephrosis, in the lever degeneration and in the spleen and lung a blood stagination are seen. The changes after transfusion with stored blood are much stronger. 6. From the results mentioned above, after transfusion with fresh hemolyzed blood the symptomatic effects as fever, drop of blood pressure are strong but ill effects upon nonprotein nitrogen and histological findings are weak. On this point the stored hemolyzed blood has ill effects stronger than that of the fresh hemolyzed blood. en-copyright= kn-copyright= en-aut-name=NishiharaYoichi en-aut-sei=Nishihara en-aut-mei=Yoichi kn-aut-name=西原庸一 kn-aut-sei=西原 kn-aut-mei=庸一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部陣内外科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1763 end-page=1770 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on Stored Blood Part 1. Glycolysis kn-title=保存血に関する研究 第1編 解糖作用 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Changes of glucose and lactic acid in stored blood was investigated and glycolysis of red cellswas experimentally studied. 1) As the storage becomes longer, glucose lessens but lactic acid increases. This change is marked until the third week and from the forth week they show no definite change. The dereasing of glucose and the increasing of lactic acid are nearly in proportion. 2) The glycolysis of red cells of stored blood in physiological saline solution after 24-hour and 6-hour heating was measured. 3) The glycolysing power after 24-hour heating is much stronger than that after 6-hour heating. 4) The glycolysis of red cells in stored blood shows a same tendency to that in physiological saline solution. 5) The change from glucose to lactic acid is performed in blood almost completly while in physiological saline solution it works weaker. en-copyright= kn-copyright= en-aut-name=NishiharaYoichi en-aut-sei=Nishihara en-aut-mei=Yoichi kn-aut-name=西原庸一 kn-aut-sei=西原 kn-aut-mei=庸一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部陣内外科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1705 end-page=1723 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental stadies on the circulatory disturbance of the lower colom due to the ligation of A. meseterica caudalis. Part Ⅱ Experimental study on the blood supply after Amputatio-recti and Anterior resection on high ligation of A. mesenterica caudalis kn-title=尾側腸間膜動脈結紮による大腸下部の血行障害に関する実験的研究 後編 尾側腸間膜動脈結紮による大腸下部切除乃至切断術後の血流に就いての実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=From the Ⅱ surgical department of the Okayama University Medical School. Director; formerly; Prof emeritus Seiji Tsuda, M.D. present; Prof. Terutake Sunada, M. D. The arterial arrangements and the collateral circulation have been studied after the high ligation of the inferior mesenterie artery and the anterior resection of the sigmoid colon and amputatio-recti in 15 dogs. The dogs were killed at various intervals and injected with a radiopaque medium through the thoratic aorta. Arteriographs were taken of the specimen. The collateral circulation after the anterior resection of sigmoid colon and amputatiorecti, has not been interrupted, and and necrotic change and insuficiency were not morphologically & histologically recognized. The anal function in the amputatio-recti with preservation of the sphincter has been recovered in 2 weeks after the Operation. en-copyright= kn-copyright= en-aut-name=HamamotoYasuo en-aut-sei=Hamamoto en-aut-mei=Yasuo kn-aut-name=浜本泰夫 kn-aut-sei=浜本 kn-aut-mei=泰夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科教室/平田市立平田博愛病院 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1683 end-page=1688 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Part Ⅲ. The effected upon the infants' bodily development by their adoption of kn-title=本邦離乳食の研究 第Ⅲ編 充分な医学的監理下に於ける離乳食摂取状態が乳児の身体発育に及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=After making experiments concerning 50 infants under a perfect medical guidance, the following results were revealed by an investigation of the relation between their ingestion of "weaning food" and their bodily growth in the weaning period. (1) When the period before the beginning of weaning (about six months after birth) was compared with its completion time (about one year after birth), it was found that Kaup's index number rather rose at the completion time. (2) As to those infants whose Kaup's index number at the completion period of weaning became less than the index seen before the starting time, the amount and the percentage of calorie of milk taken daily are less than in the case of those infants whose index number became greater at the completion period than at the beginning. (3) The body-weight at the completion time of weaning seemed to have a close relation with the whole amount of calorie and protein daily taken by infants. (4) The body-weight at the completion time of weaning was still influenced by the weight at birth, but it was much slighter than before the start of weaning. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=瀬之口スミ kn-aut-sei=瀬之口 kn-aut-mei=スミ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部小児科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1667 end-page=1682 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Part Ⅱ. Simple weaning food chiefly composed of kn-title=本邦離乳食の研究 第Ⅱ編 主としてInstant foodを用いた簡易離乳食とその摂取状況 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Six kinds of weaning food were made chiefly of "Instant Food" and with them 50 healthy infants were fed. As a result of this experiment the following data were gained.(1) The change in the amount of porridge daily taken dy the infants were as follows: 6 months old (30-50gr.) 7 months old (50-100gr.) 8 months old (150-200gr.) 9 months old (250-300gr.) 10 months old (400-450gr.) 11 months old (450-500gr.) (2) "Flake food", which was used in order to save time in cooking porridge, was very suitable as a weaning food in the early period, and later it could be favorably replaced by soft boiled-rice, supplying enough calorie and ample protein. As the flake food Was best ingested in the 5th experiment, it was revealed that its density should be 15 % at the beginning and less than 30 % in the later period and its quantity should be as follows: 6 months old (50-90gr.) 7 months old (100-150gr.) 8 months old (200gr.) 9 months old (200gr.) 10 months old (150gr.)(3) Though "Milk Food" is better than home-made "Instant Food" in the respect of ingestion by infants; but the former is regrettbly more expensive, and the latter should be improved on the point of taste. In addition "Oatmeal" is also considered to be quite excellent as a kind of weaning food. (4) By using "Flake Food" as a short-period weaning food, those infants who were delayed in weaning could be easily made to complete weaning in 3-4 months and at the completion period the amount of calorie and protein ingested by the infants was nearly ideal. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=瀬之ロスミ kn-aut-sei=瀬之ロ kn-aut-mei=スミ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部小児科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4-2 article-no= start-page=1655 end-page=1665 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590405 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Part Ⅰ. The actual state of kn-title=本邦離乳食の研究 第Ⅰ編 離乳食の実態とそれが乳幼児身体発育に及ぼす影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=From 1952 to 1953, in the agricultural and mountaineous villages of Okayama Pref. and Hiroshima Pref., an investigation was made about the actual state of "Weaning food" for infants and its effect exerted upon their bodily development both at the period fo weaning and at the later period of infancy; 520 infants (0-2 years old) and 626 infants (3-7 years old) were used as the subjects of investigation, giving the following results: (1) Of the 520 infants chosen (0-2 years old), the percentage of undernourished infants changed monthly as follows: (0-6 months old) 21%; (7-12 months old) 25%; (1-2 years old) 33.9%. Thus the percentage rose highest at the weaning period. (2) In the monthly change in infants' body-weight, the percentage of growth was rather low at the weaning period, the boy babies showing 80% of the standard value and the girl babies 89%. (3) The research on the actual state of weaning in those regions of Japan revealed that the starting time and the weaning food used then were almost proper, but that the delay in the development of staple chief food taken and the lack in protein taken were quite remarkable. (4) It was fonfirmed those infants who were not properly weaned were suffering from malnutrition far more than those who were properly weaned. (5) Among those who were delayed in weaning, move underdeveloped infants were found than in other cases, but it seems not to be reliable from the viewpoint of sampling statistics. Such a correlative relation as seen between the body-weight at birth and the growth of infants in the later period could not be found. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=瀬之ロスミ kn-aut-sei=瀬之ロ kn-aut-mei=スミ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部小児科教室 END