start-ver=1.4
cd-journal=joma
no-vol=111
cd-vols=
no-issue=3-8
article-no=
start-page=115
end-page=124
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=第138回　岡山外科会
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=平川方久
kn-aut-sei=平川
kn-aut-mei=方久
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=111
cd-vols=
no-issue=3-8
article-no=
start-page=105
end-page=114
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Expression of DNA topoisomerase Ⅰ and Ⅱβ in the developing cerebellar plate in rat embryos
kn-title=胎児期における小脳皮質の発生とDNAトポイソメラーゼⅠおよびⅡβの発現
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=DNA topoisomerases are enzymes that catalyze topological changes of DNA by transiently cleaving one (topo Ⅰ) and a pair of complementary DNA strands (topo Ⅱβ), participating in cellular transactions of DNA. Expression of both enzymes in the developing cerebellar plate in rat embryos was studied immunohistochemically. Neuroepitheliad cells in the ventricular layer expressed topo Ⅰ and topo Ⅱβ  on embryonic day 15 (E16) and E16, respectively. On E 16-22, cells in the intermediate layer (IML) are known to undergo extensivc differentiation to become Purkinje cells and deep cerebellar neurons. Many IML cells, immunostained with not only anti-topo Ⅰ and-Ⅱβ but also-calbindin antibodies, were differentiating and migrationg to form the Purkinje cell layer. Cells in the external germinal layer (EGL) on E17, originating from the germinal trigone and spreading over the surface of cerebellar plate, expressed topo Ⅰon E17. Topo Ⅱβ immunoreactive cells, however, were not readily recognized in EGL untill E22. The topo Ⅱβ immunopositive cells resided in the ventral half of the layer, corresponding to the premigratory zone of postnatal EGL. These date suggest the involvement of topo Ⅰand Ⅱβ in DNA metabolism associated with cerebellar development in embryos, especially that of topo Ⅱβ in the processes of neuronal differentiation.
en-copyright=
kn-copyright=

en-aut-name=OgawaMakoto
en-aut-sei=Ogawa
en-aut-mei=Makoto
kn-aut-name=小川誠
kn-aut-sei=小川
kn-aut-mei=誠
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部解剖学第三講座
en-keyword=ラット小脳発生
kn-keyword=ラット小脳発生
en-keyword=小脳板
kn-keyword=小脳板
en-keyword=DNA トポイソメラーゼⅠ
kn-keyword=DNA トポイソメラーゼⅠ
en-keyword=DNA トポイソメラーゼⅡβ
kn-keyword=DNA トポイソメラーゼⅡβ
en-keyword=免疫組織化学
kn-keyword=免疫組織化学
END

start-ver=1.4
cd-journal=joma
no-vol=111
cd-vols=
no-issue=3-8
article-no=
start-page=95
end-page=104
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Stress raises intraocular pressure in rabbits
kn-title=ストレスが眼圧に与える影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Purpose. To test whether encagement and volume load as stressors influence the intraocular pressure in rabbits.
Method. Rabbits were encaged for an hour in a horizontally-plastic tube with an internal diameter of 13.2 cm and a length of 33.2cm. After the encagement, rabbits received a rapid intraveonus drip infusion of 5% glucose solution, 20 ml per kilogram of body weight, for 5-6 minutes. All experiments were performed at the same time of day.
Results. The intraocular pressure after encagement (11.2±3.0mmHg as a mean and standard deviation) was significantly higher compared with that of control rabbits without encagement (9.2±1.0mmHg, Student t-test,p=0.046). This differnce became signifficantly larger when volume load was exerted on both groups of rabbits (p=0.0007). Serum levels of cortisol, adrenaline, and nordrenaline were significantly elevated afte encagement (n=6, p=0.0002, p=0.027, p=0.030, respectively). Venous pressure of the ear tended to increase in rabbits after encagement (15.8±3.1mmHg) compared with that of control rabbits (8.5±2.3mmHg,p=0.11), and the difference became significant when volume load was placed on each group of rabbits (p=0.021).
Conclusions.Encagement, especially in combination with volume losd, increased the intraocular pressure in rabbits. The elevation of peripheral venous pressure caused by an increase in serum catecholamines would underlie the elevation of intraocular pressure proh-ably through the increased outflow resistance.
en-copyright=
kn-copyright=

en-aut-name=MiyazakiYoshinori
en-aut-sei=Miyazaki
en-aut-mei=Yoshinori
kn-aut-name=宮﨑義則
kn-aut-sei=宮﨑
kn-aut-mei=義則
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部眼科学講座
en-keyword=stress
kn-keyword=stress
en-keyword=intraocular pressure
kn-keyword=intraocular pressure
en-keyword=cortisol
kn-keyword=cortisol
en-keyword=catecholamines
kn-keyword=catecholamines
en-keyword=venus pressure
kn-keyword=venus pressure
END

start-ver=1.4
cd-journal=joma
no-vol=111
cd-vols=
no-issue=3-8
article-no=
start-page=85
end-page=93
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Present status and problems of visiting nurse station
kn-title=病院基盤の訪問看護ステーションの問題点 ―患者67名からの検討―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We investigated the curent status of home nursing in our instiution, and visiting nurses' station "chime", to clarify current problems and possible improvements in home care service. A large number of the subjects were aged, and had various diseases usually involving cerebrovascular disorder. Patients requiring medical treatment comprised less than half, and it was considered that support was strong in the current home nursing siuation, particulrly. We examined the age status of persons who looked after the patients, and tce burden on women who provided care. Furthemore, problems with the prenent visit nursing syntem were evaluated by an anonymous questionnaire survey of patients and their attendants. Many of the subjects were worried or troubled about what to do about exacerbation or sudden chages of he patients' condition, the health of the caretakers, and the tight schedule of the caretakers'　life. Based on the results of this questionnaire, we would like to improve the cooperation among members the visting nurse staff including doctors, and physiotherapists so that each of them may better play their roles and provide more appropriate nursing based on the wishes and needs of indvidual patients patients and their caretakers rather than those of the uniform service.
en-copyright=
kn-copyright=

en-aut-name=MimuraYukari
en-aut-sei=Mimura
en-aut-mei=Yukari
kn-aut-name=三村由香里
kn-aut-sei=三村
kn-aut-mei=由香里
aut-affil-num=1
ORCID=

en-aut-name=MakinoHirofumi
en-aut-sei=Makino
en-aut-mei=Hirofumi
kn-aut-name=槇野博史
kn-aut-sei=槇野
kn-aut-mei=博史
aut-affil-num=2
ORCID=

en-aut-name=OkaYouko
en-aut-sei=Oka
en-aut-mei=Youko
kn-aut-name=岡庸子
kn-aut-sei=岡
kn-aut-mei=庸子
aut-affil-num=3
ORCID=

en-aut-name=WatanabeKimiko
en-aut-sei=Watanabe
en-aut-mei=Kimiko
kn-aut-name=渡辺君子
kn-aut-sei=渡辺
kn-aut-mei=君子
aut-affil-num=4
ORCID=

en-aut-name=KanamiHifumi
en-aut-sei=Kanami
en-aut-mei=Hifumi
kn-aut-name=金見一ニ三
kn-aut-sei=金見
kn-aut-mei=一ニ三
aut-affil-num=5
ORCID=

en-aut-name=MoriwakiKazuhiko
en-aut-sei=Moriwaki
en-aut-mei=Kazuhiko
kn-aut-name=森脇和彦
kn-aut-sei=森脇
kn-aut-mei=和彦
aut-affil-num=6
ORCID=

en-aut-name=KatayamaEriko
en-aut-sei=Katayama
en-aut-mei=Eriko
kn-aut-name=片山江里子
kn-aut-sei=片山
kn-aut-mei=江里子
aut-affil-num=7
ORCID=

en-aut-name=FujiwaraHiromichi
en-aut-sei=Fujiwara
en-aut-mei=Hiromichi
kn-aut-name=藤原弘道
kn-aut-sei=藤原
kn-aut-mei=弘道
aut-affil-num=8
ORCID=

en-aut-name=SadakaneTakazi
en-aut-sei=Sadakane
en-aut-mei=Takazi
kn-aut-name=定金卓爾
kn-aut-sei=定金
kn-aut-mei=卓爾
aut-affil-num=9
ORCID=

en-aut-name=SatouYoshiyuki
en-aut-sei=Satou
en-aut-mei=Yoshiyuki
kn-aut-name=佐藤能之
kn-aut-sei=佐藤
kn-aut-mei=能之
aut-affil-num=10
ORCID=

en-aut-name=HayashiIppei
en-aut-sei=Hayashi
en-aut-mei=Ippei
kn-aut-name=林逸平
kn-aut-sei=林
kn-aut-mei=逸平
aut-affil-num=11
ORCID=

en-aut-name=SatouKamehiro
en-aut-sei=Satou
en-aut-mei=Kamehiro
kn-aut-name=佐藤亀弘
kn-aut-sei=佐藤
kn-aut-mei=亀弘
aut-affil-num=12
ORCID=

en-aut-name=OguraToshio
en-aut-sei=Ogura
en-aut-mei=Toshio
kn-aut-name=小倉俊郎
kn-aut-sei=小倉
kn-aut-mei=俊郎
aut-affil-num=13
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学内科学第三講座

affil-num=2
en-affil=
kn-affil=岡山大学内科学第三講座

affil-num=3
en-affil=
kn-affil=明芳会訪問介護ステーション　

affil-num=4
en-affil=
kn-affil=明芳会訪問介護ステーション　

affil-num=5
en-affil=
kn-affil=明芳会佐藤病院

affil-num=6
en-affil=
kn-affil=明芳会佐藤病院

affil-num=7
en-affil=
kn-affil=明芳会佐藤病院

affil-num=8
en-affil=
kn-affil=明芳会佐藤病院

affil-num=9
en-affil=
kn-affil=明芳会佐藤病院

affil-num=10
en-affil=
kn-affil=明芳会佐藤病院

affil-num=11
en-affil=
kn-affil=明芳会佐藤病院

affil-num=12
en-affil=
kn-affil=明芳会佐藤病院

affil-num=13
en-affil=
kn-affil=岡山大学保健管理センター
en-keyword=在宅医療
kn-keyword=在宅医療
en-keyword=訪問看護
kn-keyword=訪問看護
en-keyword=脳血管障害
kn-keyword=脳血管障害
en-keyword=痴呆
kn-keyword=痴呆
en-keyword=ADL (activing of daily living)
kn-keyword=ADL (activing of daily living)
END

start-ver=1.4
cd-journal=joma
no-vol=111
cd-vols=
no-issue=3-8
article-no=
start-page=71
end-page=83
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Electroencephalographic changes during open-heart surgery with extracorporeal circulation and hypothermia in children
kn-title=体外循環と低体温法を用いた小児開心手術中の脳波変化に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=An electroencephalographic (EEG) study eith a multi-channel digital record was carried out to investigate EEG changes and their spatial characteristics accompanying hypothermia and cerebral ischemia during open-heart surgery in children. Subjects consisited of 10 children, ranging from 1 year 6 months to 4 years 6 months old, who underwent open-heart surgery with extracorporeal circulation and hypothermia. The EEG changes were evaluated visually and analyzed using a computer. (1) A discontinuous EEG pattern was notted during cooling in addition to commonly observed finding inculuding a decrease in fast waves, slowing and amplitude reduction, and was considered caused by rapid and transient suppression of cerebral function. (2) Power spectral and topographical analyses revealed a prominent decrease in fast waves and a relative increase in slow waves during cooling. Durong cerebral ischemia, in contrast, an actual increase in slow waves and decrease in fast waves were observed. (3) We noted the characteristics of bilateral synchronous rhythmic high-voltage slow waves among various types of transient EEG abnor-malities. (4) EEG changes induced by hypothermia differed by brain region. (5) EEG changes induced by hypothermia were influenced not only by body temperature itself but also by the rate of change in body temperature.
en-copyright=
kn-copyright=

en-aut-name=AkiyamaTomoyuki
en-aut-sei=Akiyama
en-aut-mei=Tomoyuki
kn-aut-name=秋山倫之
kn-aut-sei=秋山
kn-aut-mei=倫之
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部小児神経学講座
en-keyword=小児心臓手術
kn-keyword=小児心臓手術
en-keyword=低体温
kn-keyword=低体温
en-keyword=体外循環
kn-keyword=体外循環
en-keyword=脳波分析
kn-keyword=脳波分析
END

start-ver=1.4
cd-journal=joma
no-vol=111
cd-vols=
no-issue=3-8
article-no=
start-page=61
end-page=69
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Aging and exocrine pancreatic function evaluated by endoscopic retrograde aspiration of pure pancreatic juice
kn-title=膵外分泌機能の加齢による変化 ―内視鏡的純粋膵液採取法による検討―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=I syudied the relationship between aging and exocrine pancreatic function by endoscopic retrograde aspiration of pure pancreatic juice (PPJ). Control subjects consisted of 65 out-patients presenting mild vague abdominal aymptoms who fulfilled the following three criteria : 1) good general condition with no known organic diseaes ; 2) no abnormality in the live, bile duct, pancreas. kidney or metabolism ; 3) no alcohol consumption. Nineteen patients with definite pancreatitis were also studied. PPJ was collected form within the pancreatic duct by endoscopic retrograde catheterization of the papilla for 10 minutes after a bolus intravenous injection of secretion (Secrepan, Eisai co., Ltd., 100 U/bpdy). Exocrine pancreatic function was evaluated three parameters as fillows : secretory volume, maximal bicarbonate concentration or bicarbonate output, and enyme (amyase and lipase) output. The ordinary duodenal secretin test was also performed. Exocrine pancreatic function (both duct-cell and acinar-cell function) was significantly reduced in the elderly. The age-associated reduction showed a different pattern between duct-cell and acinar-cell function. The degree of duct-cell dysfunction was significantly higher than that of acinar-cell dysfuntion in the elderly. Influence of aging on maximal bicarbonate concentration was more clearly demonstrated by PPJ aspiration than by the ordinary secretin test. Elderly controls showed as much exocrine dysfuction as patients with chronic pancreatitis, making it difificult to diagnose chronic pancreatitis based on the exocrine function test alone. Therfore, clinical symptoms and findings as well as imaging tests should be considered for the correct diagnosis.
en-copyright=
kn-copyright=

en-aut-name=IshibashiTadaaki
en-aut-sei=Ishibashi
en-aut-mei=Tadaaki
kn-aut-name=石橋忠明
kn-aut-sei=石橋
kn-aut-mei=忠明
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第二内科教室
en-keyword=加齢
kn-keyword=加齢
en-keyword=膵外分泌機能
kn-keyword=膵外分泌機能
en-keyword=内視鏡的純粋膵液採取法
kn-keyword=内視鏡的純粋膵液採取法
en-keyword=セクレチン試験
kn-keyword=セクレチン試験
en-keyword=慢性膵炎
kn-keyword=慢性膵炎
END

start-ver=1.4
cd-journal=joma
no-vol=111
cd-vols=
no-issue=3-8
article-no=
start-page=51
end-page=60
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Characteristics of elderly patients who stopped receiving day service at a welfare facility
kn-title=デイサービス中断の要因 ―女性の場合―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To cope with problems resulting from a rapidly aging society with a low birth rate, effective methods must be established to support home care services through a welfare service system. Characteristics of 40 elderly women living in S City with their familes who had stopped receiving "day service" (discontinued group) were compared with 40 age-matched elderly women selected among those regularly receiving the day service st the same facility. In addition, factors that influenced the women to stop receiving "day service" were studied. A questionnaire consisting of 20 items concerning various activies of daily living (ADL), instrumental ADL(IADL), health states, ecnomical coditions, and reasons for quiting the service was completed by all subjects. The results showed that ADL, IADL and health staes were significantly lower in the discontinued group than those of the control group. About half of the elderly in the dis-continued group quit the services in order to receive medical care at medical institutes. These women were older in age and lower ADL and IADl than those who quit for other reasons. Time needed to care for their husbands and housekeeping, were also reasons for qutiting the day service in the relatively younger group whose ADL snd IADL were well maintitained. Therefore, I concluded that "day service at welfare facilities" may become competitive with medical and health facilities already supporting home care services for the aged. if knowledge increases about social resources to support home care services.
en-copyright=
kn-copyright=

en-aut-name=OkanoHatsue
en-aut-sei=Okano
en-aut-mei=Hatsue
kn-aut-name=岡野初枝
kn-aut-sei=岡野
kn-aut-mei=初枝
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部保健学科
en-keyword=Elderly
kn-keyword=Elderly
en-keyword=Day Service
kn-keyword=Day Service
en-keyword=ADL
kn-keyword=ADL
en-keyword=IADL
kn-keyword=IADL
en-keyword=Stop receiving services
kn-keyword=Stop receiving services
END

start-ver=1.4
cd-journal=joma
no-vol=111
cd-vols=
no-issue=3-8
article-no=
start-page=37
end-page=49
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990831
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Relationship between pysical and visual image qualiy of asymmetric screen-film syatems
kn-title=非対称増感紙-フィルムシステムの物理的画質と視覚的画質の関係
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We investigated the relationship betwwn physical and visual image quality of asymmetric screen/film systems. The physical image quality parameters included the characteristic curve, modulation transfer functin (MTF), and noise Wiener spectrum. The visual image quality indiecs, such as sharpness and grainiess, were determined using a method of paired compari-sons of ahest phantom radiographs. When the speeds of asymmetric systems increased, the visual evaluation for sharpness was lower but that for grainiess was higher.Both visual evaluations for sharpness and graininess were lower with higher kV X rays, Visual graininess was closely correlated with the Wiener spectrum, but sharpness was only slightly correlated with the MTF. The sharpness of the asymmetric systems was inferior to that of the conven-tional ratio of 1 : 2 for the front and back screens should be applied for clinical use of the asymmetric systems.
en-copyright=
kn-copyright=

en-aut-name=YoshidaAkira
en-aut-sei=Yoshida
en-aut-mei=Akira
kn-aut-name=吉田彰
kn-aut-sei=吉田
kn-aut-mei=彰
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学講座
en-keyword=Asymmetric screen-film system
kn-keyword=Asymmetric screen-film system
en-keyword=Imaging properties
kn-keyword=Imaging properties
en-keyword=Visual detection
kn-keyword=Visual detection
en-keyword=Method of paired comparisons
kn-keyword=Method of paired comparisons
en-keyword=Radiography
kn-keyword=Radiography
END