start-ver=1.4
cd-journal=joma
no-vol=109
cd-vols=
no-issue=1-2
article-no=
start-page=25
end-page=33
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical studies on choroidal circulatory disturbance : Relationship between central cerous chorioretinopathy and choroidal circulatory disturbance
kn-title=脈絡膜循環障害に関する臨床的研究―中心性漿液性脈絡網膜症と脈絡膜循環障害の関連について―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In order to know frequency of choroidal circulatory disturbance, 126 eyes with central serouse chorioretinopathy followed-up between Jan. 1985 and Dec. 1990 were retrospectively investigated by fundus fluorescein angiography. Appearance of choroidal circulatory disturbance was divided into two types. The type 1 showed choroidal filling delay at late retinal venous phase. The type 2 showed mosaic pattern of choroidal background at late retinal venous phase. Among the 126 eyes, 3 eyes were type 1 (2.4%) and 57 eyes were type 2 (45.2%), totaling 60 eyes (47.6%). Sixty-three eyes with normal part of branch retinal vein occlusion matching in sex and age were selected as controls. In the controls, no eye was type 1 (0%) and 8 eyes were type 2 (12.7%), totaling 8 eyes (12.7%). Distinctly, proportion of the type 2 was higher in central serous chorioretinopathy than in branch retinal vein occlusion. In conclusion, the pathogenesis of central serous chorioretinopathy is related to choroidal circulatory disturbance and especially mosaic pattern (type 2) was found to be a new type of circulatory disturbance.
en-copyright=
kn-copyright=

en-aut-name=KawanishiYouko
en-aut-sei=Kawanishi
en-aut-mei=Youko
kn-aut-name=河西葉子
kn-aut-sei=河西
kn-aut-mei=葉子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部眼科学教室
en-keyword=中心性漿液性脈絡網膜症
kn-keyword=中心性漿液性脈絡網膜症
en-keyword=フルオレセイン螢光造影
kn-keyword=フルオレセイン螢光造影
en-keyword=充盈遅延
kn-keyword=充盈遅延
en-keyword=モザイク模様
kn-keyword=モザイク模様
END

start-ver=1.4
cd-journal=joma
no-vol=109
cd-vols=
no-issue=1-2
article-no=
start-page=15
end-page=24
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Formation of lentoid body from retinal pigment epithelium of chick embryo in floating culture
kn-title=浮遊培養によるニワトリ胚網膜色素上皮細胞からの水晶体様構造の形成
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We observed the morphologic changes of tissue fragments of retinal pigment epithelium (RPE) of chick embryos in floating culture under the presence of bacic fibroblast growth factor (bFGF). At higher concentration (10 and 200 ng/ml) of bFGF, rolled up RPE sheets grew to develop non-pigmented lumps with the structure like onions, while dissociated RPE cells did not from such structure. Histologically, the onion-like structure consisted of lens-fiber-like cells, positive for anti-crystallin antibody and anti-bFGF-receptor antibody. This lentoid structure was not formed at 1 ng/ml or lower concentration of bFGF. The trans differentiation from RPE cells to lens epithelial cells was dependent upon the concentration of bFGF as well as the proper interaction among RPE cells.
en-copyright=
kn-copyright=

en-aut-name=TsutsuiYasuko
en-aut-sei=Tsutsui
en-aut-mei=Yasuko
kn-aut-name=筒井康子
kn-aut-sei=筒井
kn-aut-mei=康子
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部眼科学教室
en-keyword=浮遊培養
kn-keyword=浮遊培養
en-keyword=網膜色素上皮細胞
kn-keyword=網膜色素上皮細胞
en-keyword=分化転換
kn-keyword=分化転換
en-keyword=水晶体様構造
kn-keyword=水晶体様構造
en-keyword=bFGF
kn-keyword=bFGF
END

start-ver=1.4
cd-journal=joma
no-vol=109
cd-vols=
no-issue=1-2
article-no=
start-page=7
end-page=14
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Choroidal arteriole changes after experimental destruction of the outer layer of the retina
kn-title=実験的網膜外層障害モデルの脈絡膜血管の変化
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The purpose of the present study is to clarify the changes of choroidal circulation developing in the selective injuries of the outer layer of the retina. One, 2, 3 weeks and 3 months after intravenous administration of Monoiodoacetic acid in the rabbits, choroidal vessels were observed using indocyanine green angiography (ICG). The diameter of retinal arterioles decreased significantly at 3 weeks and 3 months after the treatment and hypofluorescence in the background was observed at 3 months. Histological examination revealed significant decrease in choriocapillaris at 3 weeks, a thickening of the endothelial cytoplasma and a disappearance of fenestration in choriocapillaris after 3 months. These histological findings were considered to be a cause of hypofluorescence of background in ICG. The results suggest that the selective damage of the outer layer of the retina induce changes in the choroidal circulation.
en-copyright=
kn-copyright=

en-aut-name=FujikawaEtsuko
en-aut-sei=Fujikawa
en-aut-mei=Etsuko
kn-aut-name=藤川えつこ
kn-aut-sei=藤川
kn-aut-mei=えつこ
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部眼科学教室
en-keyword=網膜外層障害
kn-keyword=網膜外層障害
en-keyword=脈絡膜循環
kn-keyword=脈絡膜循環
en-keyword=モノヨード酢酸
kn-keyword=モノヨード酢酸
en-keyword=インドシアニングリーン蛍光眼底造影
kn-keyword=インドシアニングリーン蛍光眼底造影
END

start-ver=1.4
cd-journal=joma
no-vol=109
cd-vols=
no-issue=1-2
article-no=
start-page=1
end-page=6
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Cerebral dysgenesis and psychomotor retardation in neonatal epilepsy
kn-title=新生児期発症のてんかんにおける脳形成障害および心身障害についての検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A clinical and neuroradiological study was carried out to clarify the relationship among cerebral dysgenesis, psychomotor retardation and neonatal epilepsy. Twenty-one cases with epilepsy developed within four weeks after birth were selected among 770 in-patients with childhood epilepsy. They consisted of one benign familial neonatal convulsion, nine of early myoclonic encephalopathy, four of Ohtahara syndrome, six of symptomatic localizationrelated epilepsy, and one of undetermined epilepsy. Seven cases with non specific types of epilepsies were investigated in detail. They developed into four of frontal lobe epilepsy, one of temporal lobe epilepsy and one severe epilepsy with multiple independent spike foci. Psychomotor retardation was observed in six of seven cases, and cerebral dysgenesis was considered to be important as an etiological factor. Proton MR spectroscopy revealed the decrease in the ratio of N-acetylaspartate/choline in the area with heterotopic gray matter and in the side of hemimegalencephaly, contrasted with a contralateral area without lesions. These findings can be inferred to reflect the decreased numbers of neuronal cell population or reduced metabolism in the lesions.
en-copyright=
kn-copyright=

en-aut-name=SanadaSatoshi
en-aut-sei=Sanada
en-aut-mei=Satoshi
kn-aut-name=真田敏
kn-aut-sei=真田
kn-aut-mei=敏
aut-affil-num=1
ORCID=

en-aut-name=OkaEiji
en-aut-sei=Oka
en-aut-mei=Eiji
kn-aut-name=岡�^次
kn-aut-sei=岡
kn-aut-mei=�^次
aut-affil-num=2
ORCID=

en-aut-name=OhtaharaShunsuke
en-aut-sei=Ohtahara
en-aut-mei=Shunsuke
kn-aut-name=大田原俊輔
kn-aut-sei=大田原
kn-aut-mei=俊輔
aut-affil-num=3
ORCID=

en-aut-name=KawaharaMichiko
en-aut-sei=Kawahara
en-aut-mei=Michiko
kn-aut-name=河原道子
kn-aut-sei=河原
kn-aut-mei=道子
aut-affil-num=4
ORCID=

en-aut-name=SakaeKatsuyoshi
en-aut-sei=Sakae
en-aut-mei=Katsuyoshi
kn-aut-name=栄勝美
kn-aut-sei=栄
kn-aut-mei=勝美
aut-affil-num=5
ORCID=

en-aut-name=HirakiYoshio
en-aut-sei=Hiraki
en-aut-mei=Yoshio
kn-aut-name=平木祥夫
kn-aut-sei=平木
kn-aut-mei=祥夫
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部小児神経科

affil-num=2
en-affil=
kn-affil=岡山大学医学部小児神経科

affil-num=3
en-affil=
kn-affil=岡山大学医学部小児神経科

affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線科

affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線科

affil-num=6
en-affil=
kn-affil=岡山大学医学部放射線科
en-keyword=新生児期
kn-keyword=新生児期
en-keyword=局在関連性てんかん
kn-keyword=局在関連性てんかん
en-keyword=心身障害
kn-keyword=心身障害
en-keyword=脳形成障害
kn-keyword=脳形成障害
en-keyword=MR スペクトロスコピー
kn-keyword=MR スペクトロスコピー
END