start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=287 end-page=291 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=第27回 岡山リウマチ研究会 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=InoueHajime en-aut-sei=Inoue en-aut-mei=Hajime kn-aut-name=井上一 kn-aut-sei=井上 kn-aut-mei=一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=281 end-page=285 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Establishment of home care patient support system: Okayama Central Hospital experience kn-title=当院における新しい在宅ケア支援システムについて en-subtitle= kn-subtitle= en-abstract= kn-abstract=We established a system to serve aged and disabled people within their neighborhood area. This system consists of visiting nursing service and an institutional care unit, both of which were directed by a managing bureau called the “Life assistance bureau”. This bureau investigates the needs of patients, negotiates with the government, supervises members and is authorized to plan budget and personnel affairs. Activities in one representative case handled by this bureau are reported. en-copyright= kn-copyright= en-aut-name=TakaiKenichi en-aut-sei=Takai en-aut-mei=Kenichi kn-aut-name=高井研一 kn-aut-sei=高井 kn-aut-mei=研一 aut-affil-num=1 ORCID= en-aut-name=IkedaToshiko en-aut-sei=Ikeda en-aut-mei=Toshiko kn-aut-name=池田俊子 kn-aut-sei=池田 kn-aut-mei=俊子 aut-affil-num=2 ORCID= en-aut-name=MiyasatoMisa en-aut-sei=Miyasato en-aut-mei=Misa kn-aut-name=宮里美佐 kn-aut-sei=宮里 kn-aut-mei=美佐 aut-affil-num=3 ORCID= en-aut-name=YamaneYoko en-aut-sei=Yamane en-aut-mei=Yoko kn-aut-name=山根洋子 kn-aut-sei=山根 kn-aut-mei=洋子 aut-affil-num=4 ORCID= en-aut-name=KaneshigeTetzuzo en-aut-sei=Kaneshige en-aut-mei=Tetzuzo kn-aut-name=金重哲三 kn-aut-sei=金重 kn-aut-mei=哲三 aut-affil-num=5 ORCID= en-aut-name=KitanosakoHarumi en-aut-sei=Kitanosako en-aut-mei=Harumi kn-aut-name=北之迫晴美 kn-aut-sei=北之迫 kn-aut-mei=晴美 aut-affil-num=6 ORCID= en-aut-name=KanemasaYasuhiro en-aut-sei=Kanemasa en-aut-mei=Yasuhiro kn-aut-name=金政泰弘 kn-aut-sei=金政 kn-aut-mei=泰弘 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山中央病院内科 affil-num=2 en-affil= kn-affil=岡山中央病院在宅医療科 affil-num=3 en-affil= kn-affil=岡山中央病院在宅医療科 affil-num=4 en-affil= kn-affil=岡山中央病院作業療法室 affil-num=5 en-affil= kn-affil=岡山中央病院泌尿器科 affil-num=6 en-affil= kn-affil=訪問看護ステーション鴻仁 affil-num=7 en-affil= kn-affil=岡山県立大学保健福祉学部看護学科 en-keyword=在宅ケア kn-keyword=在宅ケア en-keyword=生活支援部 kn-keyword=生活支援部 en-keyword=訪問看護 kn-keyword=訪問看護 END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=275 end-page=280 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Co-operative team care for home care nursing kn-title=訪問看護におけるチームケアの取り組み en-subtitle= kn-subtitle= en-abstract= kn-abstract=The process of establishing a network between several professions involved in the home care nursing system is reported. This system gave satisfactory support to patients in their home. The frequency of visits by occupational therapists was 45%, 44% for case workers, 44% for visiting nurses from our hospital, 7% for pharmacists, and 3% for dieticians other than doctors and community nurses. For patients residing outside the Okayama Central Hospital areas, the frequency of visits by assistants was 13%, 7% for day care units, and 6% for public health nurses other than doctors and community nurses. Co-operative involvement in the care management of patients was beneficial to the home care nursing system because the needs of patients could be more easily met by members of different professions and opinions from different perspectives improved the quality of patient care. The quality of care management was evaluated and two cases are described. en-copyright= kn-copyright= en-aut-name=TakaiKenichi en-aut-sei=Takai en-aut-mei=Kenichi kn-aut-name=高井研一 kn-aut-sei=高井 kn-aut-mei=研一 aut-affil-num=1 ORCID= en-aut-name=OhtaSachiko en-aut-sei=Ohta en-aut-mei=Sachiko kn-aut-name=大田祥子 kn-aut-sei=大田 kn-aut-mei=祥子 aut-affil-num=2 ORCID= en-aut-name=IkedaToshiko en-aut-sei=Ikeda en-aut-mei=Toshiko kn-aut-name=池田俊子 kn-aut-sei=池田 kn-aut-mei=俊子 aut-affil-num=3 ORCID= en-aut-name=MiyasatoMisa en-aut-sei=Miyasato en-aut-mei=Misa kn-aut-name=宮里美佐 kn-aut-sei=宮里 kn-aut-mei=美佐 aut-affil-num=4 ORCID= en-aut-name=KaneshigeTetzuzo en-aut-sei=Kaneshige en-aut-mei=Tetzuzo kn-aut-name=金重哲三 kn-aut-sei=金重 kn-aut-mei=哲三 aut-affil-num=5 ORCID= en-aut-name=KawaiTakako en-aut-sei=Kawai en-aut-mei=Takako kn-aut-name=川合貴子 kn-aut-sei=川合 kn-aut-mei=貴子 aut-affil-num=6 ORCID= en-aut-name=HarutaYasumi en-aut-sei=Haruta en-aut-mei=Yasumi kn-aut-name=春田康美 kn-aut-sei=春田 kn-aut-mei=康美 aut-affil-num=7 ORCID= en-aut-name=KitanosakoHarumi en-aut-sei=Kitanosako en-aut-mei=Harumi kn-aut-name=北之迫晴美 kn-aut-sei=北之迫 kn-aut-mei=晴美 aut-affil-num=8 ORCID= en-aut-name=TakahashiKayo en-aut-sei=Takahashi en-aut-mei=Kayo kn-aut-name=高橋香代 kn-aut-sei=高橋 kn-aut-mei=香代 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山中央病院内科 affil-num=2 en-affil= kn-affil=岡山中央病院内科 affil-num=3 en-affil= kn-affil=岡山中央病院在宅医療科 affil-num=4 en-affil= kn-affil=岡山中央病院在宅医療科 affil-num=5 en-affil= kn-affil=岡山中央病院泌尿器科 affil-num=6 en-affil= kn-affil=訪問看護ステーション鴻仁 affil-num=7 en-affil= kn-affil=訪問看護ステーション鴻仁 affil-num=8 en-affil= kn-affil=訪問看護ステーション鴻仁 affil-num=9 en-affil= kn-affil=岡山大学教育学部養護教諭養成課程 en-keyword=在宅医療 kn-keyword=在宅医療 en-keyword=チームケア kn-keyword=チームケア en-keyword=ケアマネジメント kn-keyword=ケアマネジメント en-keyword=訪問看護 kn-keyword=訪問看護 END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=267 end-page=274 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Determinant of the medical expenses of the elderly during the last seven month period of life kn-title=高齢者の死亡前医療費に関する決定要因の定量的分析 en-subtitle= kn-subtitle= en-abstract= kn-abstract=This study evaluated medical expenses during the last seven months of life in elderly patients aged seventy and over in a rulal town in Okayama prefecture from January 1992 to March 1995, using data from death certificates and medical fee claim records of the elderly. The findings were as follows : 1. The monthly expenses increased toward the last month of life. 2. In the multiple regression model, five independent variables (length of hospital stay, malignant disease, cerebral vascular desease, place of death, services of a visiting nurse) accounted for about 60% of the variance in medical expenses during the last seven-month period. 3. Inflation of medical expenses of the elderly during the premortem period of life was mainly related to long-term hospitalization. 4. In analysing medical expenses, controlling various factors related to long-term hospitalization was found to be important. en-copyright= kn-copyright= en-aut-name=TaniharaShinichi en-aut-sei=Tanihara en-aut-mei=Shinichi kn-aut-name=谷原真一 kn-aut-sei=谷原 kn-aut-mei=真一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学教室 en-keyword=老人医療費 kn-keyword=老人医療費 en-keyword=集中度 kn-keyword=集中度 en-keyword=死亡前医療費 kn-keyword=死亡前医療費 en-keyword=高齢社会 kn-keyword=高齢社会 en-keyword=重回帰分析 kn-keyword=重回帰分析 END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=253 end-page=266 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Analysis of dopamine receptor and dopamine transporter genes in schizophrenia kn-title=ドパミン受容体とドパミントランスポーターの遺伝子多型に基づいた精神分裂病の分子遺伝学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Four studies on variants of the D2 receptor gene (Ser→Cys), Bal 1 polymorphism in D3, 48-nucleotide repeat polymorphism in D4, and 40-nucleotide repeat polymorphism in the dopamine transporter gene were carried out in patients with schizophrenia (n=73), mood disorder (n=11), neurological disease (n=41) and controls (n=29). Each polymorphism was typed by amplification of genomic DNA by PCR and agarose gel electrophoresis. Eight individuals were heterozygous for Cys/Ser 311 of D2 and three of these eight were schizophrenia patients and two of the three had family histories of the illness. Two patients with schizophrenia were homozygous for the mutant form of D3 and showed a stuporous state at disease onset. It was detected that four-fold and two-fold repeats in D4, and ten-fold, nine-fold and seven-fold repeats in the dopamine transporter gene. There was no evidence of association between any of these variants and reactivity to pharmacotherapy for schizophrenia. en-copyright= kn-copyright= en-aut-name=YamaguchiKoji en-aut-sei=Yamaguchi en-aut-mei=Koji kn-aut-name=山口耕司 kn-aut-sei=山口 kn-aut-mei=耕司 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部神経精神医学教室 en-keyword=ドパミン受容体 kn-keyword=ドパミン受容体 en-keyword=ドパミントランスポーター kn-keyword=ドパミントランスポーター en-keyword=遺伝子多型 kn-keyword=遺伝子多型 en-keyword=精神分裂病 kn-keyword=精神分裂病 END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=241 end-page=252 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Hemodynamic and hormonal changes under the biventricular bypass system with ventricular fibrillated hearts kn-title=心室細動下両心バイパス型人工心臓における循環及び内分泌動態の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Hemodynamic and hormonal changes were studied in 13 sheep whose entire circulation was maintained by a biventricular bypass system with a pair of pusher-plate type blood pumps. Ventricular fibrillation was induced and pneumatically driven pumps placed outside the body kept the animals alive for 2-48 days (average: 11 days). Pump output and aortic pressure stayed within physiological ranges, but central venous pressure was elevated from 5 to 10-13 ㎜Hg after surgery. Serum levels of antidiuretic hormone, cortisol and insulin were stabilized soon after surgery. Adrenaline level and renin activity did not change significantly. For unknown reasons, the noradrenaline level showed a temporary increase after a week. Atrial natriuretic peptide (ANP) increased significantly 5 days after surgery. There were significant drops in triiodothyronine (T(3)) and thyroxine (T(4)) levels after surgery with gradual recovery afterward to 40% and 50% of the control levels, respectively. These results suggested that the biventricular bypass system maintained hemodynamic conditions similar to those maintained by the natural heart, although ANP, T(3) and T(4) values were changed. en-copyright= kn-copyright= en-aut-name=NakayamaHironobu en-aut-sei=Nakayama en-aut-mei=Hironobu kn-aut-name=中山裕宣 kn-aut-sei=中山 kn-aut-mei=裕宣 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=左右非同期 variable rate mode kn-keyword=左右非同期 variable rate mode en-keyword=両心バイパス型人工心臓 kn-keyword=両心バイパス型人工心臓 en-keyword=甲状腺ホルモン kn-keyword=甲状腺ホルモン en-keyword=心房性ナトリウム利尿ペプタイド kn-keyword=心房性ナトリウム利尿ペプタイド END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=225 end-page=240 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Spectrum analysis of arterial blood pressure waveforms kn-title=動脈圧波形の形状変化に対する周波数解析による検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is known that the shape of arterial blood pressure waveform reflects the hemodynamic status, but quantitative analyses of waveform are seldom reported. In this study, the arterial pressure wave was recorded with an intra-arterial catheter and pressure transducer, converted to digital data, and stored in a computer. The data were analyzed by two methods of spectrum analyses, i.e., fast Fourier transform (FFT for both power spectrum and phase information) and the autoregressive model (ARM). Pressure waveforms during normotension were compared with pressure waveforms during hypotension induced by vasodilators (sodium nitroprusside and nitroglycerin) in the human study, and by the vasodilators, hemorrhage or 3% isoflurane in the animal study. Reconstruction of waveforms by inverse FFT was also performed, and compared with the original waveforms. FFT is more useful than ARM for analysis of data with known frequencies, such as respiratory and heart rates. Using inverse FFT, the wave can be reconstructed by the base frequency (heart rate) to 4th harmonic data with an error margin of less than 2%. The amplitude and phase information of heart rate frequency up to its 4th harmonic, and amplitude of respiratory frequency, were found to be the essential parameters to describe the shape of the arterial pressure waveform. en-copyright= kn-copyright= en-aut-name=SaitoTomohiko en-aut-sei=Saito en-aut-mei=Tomohiko kn-aut-name=齋藤智彦 kn-aut-sei=齋藤 kn-aut-mei=智彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部麻酔・蘇生学教室 en-keyword=動脈圧波形 kn-keyword=動脈圧波形 en-keyword=周波数解析 kn-keyword=周波数解析 en-keyword=フーリエ変換 kn-keyword=フーリエ変換 en-keyword=自己回帰モデル kn-keyword=自己回帰モデル END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=215 end-page=223 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serum levels of macrophage colony stimulating factor and other acute phase reactants after open heart surgery kn-title=開心術後における Macrophage Colony-Stimulating Factor と急性相反応物質の血中動態について en-subtitle= kn-subtitle= en-abstract= kn-abstract=To clarify the phathophysiological role of macrophage colony stimulating factor (M-CSF) in the healing processes of inflammation, we studied chronological changes in serum concentrations of M-CSF and other reactants during the acute phase of inflammation in patients who underwent open heart surgery, since these patients showed a precise point of tissue damage. The number of neutrophilic leukocytes increased in the very early postoperative stage, reached a peak 48 h after surgery and declined to the basal level at day 14. The chronological changes in serum C-reactive protein level after surgery were similar to these of neutrophic leukocytes. Serum M-CSF concentrations increased gradually, reached a peak 7 days after surgery and remained at that level until day 14. Based on these phenomena, it is assumed that M-CSF plays a pathophysiological role in the healing processes of an inflammation. Measurement of the serum concentration of M-CSF would be useful for evaluating the process of inflammation. en-copyright= kn-copyright= en-aut-name=ChikakiyoHirokazu en-aut-sei=Chikakiyo en-aut-mei=Hirokazu kn-aut-name=近清裕一 kn-aut-sei=近清 kn-aut-mei=裕一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部公衆衛生学教室 en-keyword=M-CSF kn-keyword=M-CSF en-keyword=開心術 kn-keyword=開心術 en-keyword=白血球数 kn-keyword=白血球数 en-keyword=急性相反応物質 kn-keyword=急性相反応物質 en-keyword=サイトカイン kn-keyword=サイトカイン END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=203 end-page=214 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Potential role of granulocyte colony stimulating factor in treating urinary tract infection kn-title=尿路感染症治療における Granulocyte Colony-Stimulating Factor (G-CSF) の有用性に関する基礎的検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The priming effects of granulocyte colony stimulating factor (G-CSF) on neutrophil function and anti-pseudomonal activity were examined under various osmotic conditions created with urea and NaCL (280mOsm., 400mOsm., 800mOsm.) in vitro. Consequently, the prophylactic effect of G-CSF on post-operative urinary tract infection after transurethral resection of the prostate were examined experimentally. As a result, neutropil chemiluminescence was significantly enhanced by G-CSF under physiological osmotic conditions. However, enhancement was not observed under hyperosmotic conditions as in the urine. Similarly, the anti-pseudomonal activity of human neutrophils was not enhanced by G-CSF under hyperosmotic condition. However, whole blood chemiluminescence in patients after transurethral resection of the prostate was significantly enhanced by the administration of G-CSF. Moreover, postoperative urinary tract infection, considered an infection of the submucosal layer, was not obsereved, suggesting that the neutrophil priming effect occurred in the submucosal layer not in the urinary tract. en-copyright= kn-copyright= en-aut-name=HataKazuhiro en-aut-sei=Hata en-aut-mei=Kazuhiro kn-aut-name=畠和宏 kn-aut-sei=畠 kn-aut-mei=和宏 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部泌尿器科学教室 en-keyword=urinary tract infection kn-keyword=urinary tract infection en-keyword=G-CSF kn-keyword=G-CSF en-keyword=chemiluminescence kn-keyword=chemiluminescence en-keyword=neutrophil function kn-keyword=neutrophil function END