Wiley Acta Medica Okayama 2050-0904 10 7 2022 Lotus root-like appearance in the left anterior descending artery treated with a drug-coated balloon angioplasty e06028 EN Wataru Takagi Department of Cardiology, Kagawa Prefectural Central Hospital Tomoaki Okada Department of Cardiology, Kagawa Prefectural Central Hospital Kazumasa Nosaka Department of Cardiology, Kagawa Prefectural Central Hospital Toru Miyoshi Department of Cardiovascular Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Masayuki Doi Department of Cardiology, Kagawa Prefectural Central Hospital A lotus root-like appearance of the coronary artery diagnosed by optical coherence tomography (OCT) is characterized by old coronary thrombi that form small lumen channels. Herein, serial OCT images of a left anterior descending artery with a lotus root-like appearance, treated with drug-coated balloon angioplasty are described. No potential conflict of interest relevant to this article was reported.