保存血大量輪血に伴う出血傾向に対する線維素溶解現象の発現とその対策 第2編 保存血大量輸血時の線維溶解現象発現に対する対策

Therapeutic and prophylactic measures against a fibrinolysis following massive transfusion of preserved blood was studied, and following results were obtained. 1. Administration of ε-aminocaplonic acid, ACTH, and cortisone prevented a fibrinolysis following massive transfusion of preserved blood. 2. These therapeutics, especially, showed a marked preventive effect when they were applied together at early stage. 3. At the same time in the cases administed together with thromboplastin and adrenochrome preparations of every kinds as well as fresh blood, fibrinolysis was not completely prevented, but those were expected to inhibit other disturbance in coagulation mechanism accompanied with the above phenomenon.