組織酸素消費に及ぼす高水圧の影響のOxigraph的研究 第2編 諸組織酸素消費に及ぼす高水圧の影響

By Oxigraph the oxygen consumption of tissues under high hydrostatic pressure can be measured continuously during the compression. The author studied the influence of high hydrostatic pressure upon the oxygen consumption of excised tissues of frog, suspension of Bac. coli communis and lymphocytes of young dog by use of the Oxigraph. Results are as follows; (A) Excised tissues of Rana nigro-maculata 1) Oxygen consumption of excised muscle, cerebrum, heart and kidney were accelerated under 100, 300 and 500 Kg/㎠ . Such acceleration continues unchanged during the whole course of compression. 2) Under 1,000 and 1.500 Kg/㎠ . pressure, oxygen consumption of excised tissues are inhibited in proportion to the strength of applied pressure after initial acceleration in general. 3) Pressure effect, on flits It and cerebrum disappears inuuediately by decompression. On the other band, excised heart is ienerally insensitive to pressure change. (B) Suspension of Bac. coli conununis 1) Oxygen consumption of Bac. coli communis is inhibited by 100-2000 Kg/㎠ . pressure in proportion to the strength of the pressure. Inhibitory effect continues constantly under such pressures. 2) When the temperature of the medium is raised, the inhibitory effect decreases in some measure. But the oxygen consumption is never augumented above that under the normal pressure, even when the temperature rises over 37℃ . 3) Even the application of 2.000 Kg/㎠ . pressure for twenty minutes, the oxygen consumption recovers a little immediately by decompression. (C) Suspension of lymphocytes from the thymus of young dog 1) The Oxygen consumption of lymphocytes is neither increased nor decreased under 100-300 Kg/㎠ . When applied pressure exceeds 500 Kg/㎠ , inhibitory effect appears in proportion to the pressure strength. 2) By such applied presrure the inhibitory effect appears immediately and continues at a constant degree during compression for twenty minutes at least. Even in the case of 1,500 Kg/㎠ . for twenty minutes, the oxygen consumption recovers a little instantly by decompression.