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FullText URL K0005858_abstract_review.pdf K0005858_summary.pdf K0005858_fulltext.pdf
Author Sakae, Hiroyuki|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5858号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005857_abstract_review.pdf K0005857_summary.pdf K0005857_fulltext.pdf K0005857_fulltext_figure.pdf K0005857_fulltext_supplementary materials.pdf
Author Kubota, Tetsushi|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5857号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005856_abstract_review.pdf K0005856_summary.pdf K0005856_fulltext.pdf
Author Wada, Nozomu|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5856号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005855_abstract_review.pdf K0005855_summary.pdf K0005855_fulltext.pdf
Author Sakatani, Yuka|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5855号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005854_abstract_review.pdf K0005854_summary.pdf K0005854_fulltext.pdf
Author Kato, Yuka|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5854号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005853_abstract_review.pdf K0005853_summary.pdf K0005853_fulltext.pdf
Author Masuda, Kana|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5853号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005852_abstract_review.pdf K0005852_summary.pdf K0005852_fulltext.pdf
Author Ogata, Takeshi|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5852号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005851_abstract_review.pdf K0005851_summary.pdf K0005851_fulltext.pdf K0005851_fulltext_figure.pdf K0005851_fulltext_Supplementary_Figure.pdf
Author Yokomichi, Naosuke|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5851号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005850_abstract_review.pdf K0005850_summary.pdf K0005850_fulltext1.pdf
Author Fujii, Yosuke|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5850号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005849_abstract_review.pdf K0005849_Summary.pdf K0005849_fulltext.pdf
Author Kurita, Masa|
Published Date 2018-12-27
Content Type Thesis or Dissertation
Grant Number 甲第5849号
Granted Date 2018-12-27
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
JaLCDOI 10.18926/AMO/56466
FullText URL 73_1_93.pdf
Amo Type Errata
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 93
End Page 93
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/56465
FullText URL 73_1_91.pdf
Abstract In the article by Takase K et al. entitled “High-dose Dexamethasone Therapy as the Initial Treatment for Idiopathic Thrombocytopenic Purpura: Protocol for a Multicenter, Open-label, Single Arm Trial”, which appeared in the December 2018 issue, Vol.72, No.2, pp197-201, regarding the authors’ information in the first page, following corrections should be added as below.
Amo Type Errata
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 91
End Page 91
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/56464
FullText URL 73_1_85.pdf
Author Abe, Yoshiyuki| Fujibayashi, Kazutoshi| Nishizaki, Yuji| Yanagisawa, Naotake| Nojiri, Shuko| Nakano, Soichiro| Tada, Kurisu| Yamaji, Ken| Tamura, Naoto|
Abstract Pneumocystis pneumonia (PCP) due to Pneumocystis jirovecii infection is the leading cause of fatal opportunistic infections in immunocompromised patients. We will determine whether a daily sulfamethoxazole-trimethoprim (SMX/TMP) dose of 200/40 mg was non-inferior to 400/80 mg for PCP prevention in patients with systemic rheumatic disease under immunosuppressive therapy. This is a randomized, open-label, multicenter controlled trial. The primary outcome is the rate of PCP prevention at 52 weeks. The secondary outcome is the discontinuation rate of SMX/TMP. The trial will evaluate the optimal dose of SMX/TMP for PCP prevention in patients with systemic rheumatic disease under immunosuppressive therapy.
Keywords pneumocystis pneumonia prophylaxis systemic rheumatic disease sulfamethoxazole-trimethoprim conventional-dose versus half-dose
Amo Type Clinical Study Protocol
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 85
End Page 89
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30820060
JaLCDOI 10.18926/AMO/56463
FullText URL 73_1_81.pdf
Author Sugihara, Yuusaku| Harada, Keita| Oka, Shohei| Yasutomi, Eriko| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Hiraoka, Sakiko| Otsuka, Fumio| Okada, Hiroyuki|
Abstract Endoscopic submucosal dissection (ESD) is reportedly one of the standard treatment strategies for large superficial colorectal neoplasms in Japan because of its high en bloc resection rate. A few technical issues regarding ESD should be considered, one of which is the selection of the Endo-cut I mode versus the Swift-coagulation mode as the electrosurgical unit mode setting during submucosal dissection. We seek to determine which of these two modes is more suitable for submucosal dissections of colorectal tumors with regard to procedure time and safety.
Keywords endoscopic submucosal dissection electrosurgical mode colorectal tumor
Amo Type Clinical Study Protocol
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 81
End Page 84
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30820059
JaLCDOI 10.18926/AMO/56462
FullText URL 73_1_77.pdf
Author Morita, Mio| Matsumoto, Hiroshi| Shirakawa, Yasuhiro| Noma, Kazuhiro| Tanabe, Shunsuke| Kimata, Yoshihiro|
Abstract Anterior cervical plate fixation is a common surgical treatment for cervical spine trauma, disc herniation, or cervical spondylosis. Esophageal perforation following anterior cervical plate fixation is a rare but serious complication. Management of esophageal perforation is controversial; however, we suggest treating most cases surgically because this condition is slow to heal and often fatal. We managed 2 cases of esophageal perforation following anterior cervical plate fixation by flap reconstruction with the pectoralis major muscle in one case and a jejunal free flap in the other. Here, we report our experience and review the surgical indications.
Keywords anterior cervical plate fixation esophageal perforation reconstruction pectoralis major flap jejunal free flap
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 77
End Page 80
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30820058
JaLCDOI 10.18926/AMO/56461
FullText URL 73_1_71.pdf
Author Takahashi-Arimasa, Keiko| Kohno-Yamanaka, Reiko| Soga, Yoshihiko| Miura, Rumi| Morita, Manabu|
Abstract Preoperative oral care is helpful to prevent postoperative complications in patients who are undergoing esophagectomy. Here, we report the case of an 81-year-old Japanese man with an upper limb disability caused by post-polio syndrome who was receiving neoadjuvant chemotherapy for esophageal cancer. He had poor oral health status and developed oral complications as a side effect of chemotherapy. He could not brush his teeth by himself. However, infection control by oral care provided by an interprofessional collaboration successfully improved his oral hygiene, and his follow-up involved no severe complications. Interprofessional collaboration is useful especially for patients with upper limb disability.
Keywords esophageal cancer preoperative oral care post-polio syndrome neoadjuvant chemotherapy oral mucositis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 71
End Page 76
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30820057
JaLCDOI 10.18926/AMO/56460
FullText URL 73_1_67.pdf
Author Kono, Reika| Shimizu, Takehiro| Ohtsuki, Hiroshi| Hamasaki, Ichiro| Shibata, Kiyo| Kishimoto, Fumiko| Morizane, Yuki| Shiraga, Fumio|
Abstract We report a case of congenital multiple ocular motor nerve palsy combined with splitting of the lateral rectus muscle (LR). A 59-year-old Japanese female was investigated for worsening esotropia after corrective surgery. She presented with left hypertropia (35Δ) and esotropia (45-50Δ). Orbital magnetic resonance imaging (MRI) showed reduced belly sizes in the superior rectus, inferior rectus, and superior oblique muscles and splitting of the LR, extending from the origin to the belly, in the left eye. Splitting of the LR belly was detected on MRI in a case of congenital multiple ocular motor nerve palsy.
Keywords multiple ocular motor nerve palsy congenital cranial dysinnervation disorder lateral rectus muscle splitting orbital connective tissue magnetic resonance imaging
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 67
End Page 70
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30820056
JaLCDOI 10.18926/AMO/56459
FullText URL 73_1_61.pdf
Author Tamefusa, Kosuke| Ishida, Hisashi| Washio, Kana| Ishida, Toshiaki| Morita, Hirosuke| Shimada, Akira|
Abstract Patients with multi-system (MS)-type langerhans cell histiocytosis (LCH) show poor outcomes, especially congenital MS LCH cases were shown in high mortality rate. We experienced a congenital case of MS LCH with high risk organs, who needed intensive respiratory support after birth. Even though intensive chemotherapy was discontinued, this patient’s lung LCH lesions gradually became reduced and his respiratory condition recovered; therefore, we restarted and completed maintenance chemotherapy. The patient maintained complete remission for more than 4 years after the end of chemotherapy. Our case suggests that congenital MS LCH even with severe organ involvement can be treated successfully with chemotherapy.
Keywords Langerhans-cell histiocytosis congenital multisystem type
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 61
End Page 65
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30820055
JaLCDOI 10.18926/AMO/56458
FullText URL 73_1_51.pdf
Author Fujii, Masakuni| Fujimoto, Kenji| Yabe, Syuntaro| Nasu, Junichiro| Miyaike, Jiro| Yoshioka, Masao| Shiode, Junji| Yamamoto, Kazuhide| Matsuda, Shinya|
Abstract  We investigated the relationship between body mass index (BMI) and postoperative outcomes in 450 gallbladder cancer patients in Japan. We collected patient information, including sex, age, underlying disease, BMI, stage, surgery method, postoperative time to discharge, and postoperative Medicare fees, from the Japanese administrative database associated with the Diagnosis Procedure Combination system. We classified patient BMIs as underweight (BMI<18.5 kg/m2), normal (BMI≥18.5 kg/m2 and <25 kg/m2) or overweight/obese (BMI≥25 kg/m2), then investigated the relationship between these categories and two postoperative outcomes: time to discharge and postoperative Medicare fees. The median postoperative time to discharge was 12 days in all patients, and 12 days in each of the three weight groups (p=0.62, n.s.). The median postoperative Medicare fees from surgery until discharge were (USD): all patients, $5,002; underweight, $5,875; normal weight, $4,797; and overweight/obese, $5,179 (p=0.146, n.s.). A multivariate analysis with adjustment for competing risk factors revealed that BMI was not associated with increased risk of longer postoperative time to discharge (normal weight: HR 1.17, p=0.29; overweight/obese: HR 1.17, p=0.37) or higher postoperative Medicare fees (OR 0.99, p=0.86, n.s.). Thus, high BMI was not found to be a factor for poor postoperative outcomes in Japanese patients with gallbladder cancer.
Keywords body mass index gallbladder cancer surgery obesity
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 51
End Page 59
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30820054
JaLCDOI 10.18926/AMO/56457
FullText URL 73_1_43.pdf
Author Ikeda, Ailee| Takaki, Akinobu| Yasunaka, Tetsuya| Oyama, Atsushi| Adachi, Takuya| Wada, Nozomu| Onishi, Hideki| Ikeda, Fusao| Shiraha, Hidenori| Yoshida, Kazuhiro| Kuise, Takashi| Nobuoka, Daisuke| Yoshida, Ryuichi| Umeda, Yuzo| Yagi, Takahito| Fujiwara, Toshiyoshi| Okada, Hiroyuki|
Abstract Post-orthotopic liver transplantation (OLT) hepatitis B recurrence is well-controlled with a nucleos(t)ide analogue and hepatitis B immunoglobulin (HBIG) combination, but the high cost and the potential risk of unknown infection associated with HBIG remain unresolved issues. Low-cost recombinant hepatitis B virus (HBV) vaccine administration is a potential solution to these problems. We retrospectively analyzed the rate and predictive factors of HBV vaccine success in 49 post-OLT patients: liver cirrhosis-type B (LC-B), n=28 patients; acute liver failure-type B (ALF-B), n=8; and non-HBV-related end-stage liver disease (non-B ESLD) who received a liver from anti-hepatitis B core antibody-positive donors, n=13. A positive anti-hepatitis B surface antibody response was achieved in 29% (8/28) of the LC-B group, 88% (7/8) of the ALF-B group, and 44% (4/9) of the adult non-B ESLD group. All four non-B ESLD infants showed vaccine success. The predictive factors for a good response in LC-B were young age, marital donor, and high donor age. ALF-B and non-B ESLD infants are thus good vaccination candidates. LC-B patients with marital donors are also good candidates, perhaps because the donated liver maintains an efficient immune memory to HBV, as the donors had already been infected in adulthood and showed adequate anti-HBV immune responses.
Keywords acute liver failure hepatitis B hepatitis B vaccine liver cirrhosis liver transplantation
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-02
Volume volume73
Issue issue1
Publisher Okayama University Medical School
Start Page 41
End Page 50
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30820053