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JaLCDOI 10.18926/AMO/63409
FullText URL 76_2_155.pdf
Author Kimura, Jiro| Okabayashi, Takehiro| Sui, Kenta| Tabuchi, Motoyasu| Iwata, Jun| Hata, Yasuhiro| Iiyama, Tatsuo| Ono, Noriaki|
Abstract Small bowel metastasis from renal cell carcinoma (RCC) is rare, and its clinicopathological characteristics are unclear; thus, we revisited the concept of this tumor and reviewed its diagnostic and treatment modalities. We filtered MEDLINE searches of articles published in English between 1950 and 2019, and identified 100 patients who had undergone treatment, including 1 patient from our clinic. We extracted patient characteristics, treatment, and prognostic data, resulting in clinicopathological data on 100 patients (83 men, 17 women). Mean age was 63 years (range, 16-86 years). Tumor sites were duodenum, jejunum, ileum, and multiple sites in 30, 37, 25, and 7 patients, respectively. The 1-, 3-, and 5-year overall survival rates after diagnosis were 53.0%, 36.0%, and 36.0%. Curative resection patients showed 62.1% 5-year survival after surgery, vs. 27.5% in noncurative surgical management cases. Good prognoses can be expected if these tumors are identified early for complete removal. Surgery is the only curative option. To determine the best management strategy and improve prognostic accuracy, we continue to collect and analyze epidemiological and pathological data. Although this condition is rare, surgery should be considered if curative resection is expected. Prognosis after curative resection is not poor, but recurrence is not unlikely.
Keywords renal cell carcinoma small bowel metastasis intestine tumor
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 155
End Page 165
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503443
Web of Science KeyUT 000792374900007
JaLCDOI 10.18926/AMO/63408
FullText URL 76_2_145.pdf
Author Qin, Yi| Liu, Linlin| Zhu, Fanghui| Lu, Huazhen| Huang, Mingliu|
Abstract With rapidly aging populations, family care functions can become weakened, and community health services often lack unified standards. A standardized and professional community home-based long-term care model (CHLCM) for the elderly is urgently needed in many regions of China and in other countries. Here, we explored the indicators of the need for a CHLCM among elderly individuals, and we constructed a CHLCM. We created and distributed a questionnaire regarding the requirement of long-term care services, based on a literature review. The two-rounds Delphi method was used, involving 20 experts who were randomly selected from among the medical universities, community health service centers, and nursing homes in Nanning, Guangxi, China. The experts’ enthusiasm rates in the questionnaire’s two rounds were 95% and 100%, respectively. The authentic coefficient of the experts’ consulting was 0.857, and that of the experts’ academic level was 0.835; the judgement coefficient was 0.880 and the familiar coefficient was 0.855. The CHLCM includes service content and an evaluation. The coordination coefficients for the two primary, eight secondary, and 29 tertiary indicators were 0.200, 0.386, and 0.184, respectively (p<0.05). The experts’ enthusiasm and authority were high. The coordination of the experts’ agreement was sufficient, and the analysis results were reliable. The CHLCM includes 29 items that provide a foundation and references for the formulation of concrete indicators and subsequent research.
Keywords community home-based long-term care elderly indicator system
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 145
End Page 154
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503442
Web of Science KeyUT 000792374900006
JaLCDOI 10.18926/AMO/63407
FullText URL 76_2_137.pdf
Author Tsukahara, Masaru| So, Ryuhei| Yada, Yuji| Kodama, Masafumi| Kishi, Yoshiki| Yamada, Norihito|
Abstract Although reported for Caucasians, changes in plasma clozapine levels after smoking cessation in East Asians remain unclear. We here investigated plasma clozapine levels before and after smoking cessation in Japanese inpatients with schizophrenia. We conducted a retrospective chart review of 14 inpatients with schizophrenia who were being treated with clozapine between June 1, 2019, and July 31, 2019 and who were smokers as of July 1, 2019, the day on which a smoking ban was instituted in the tertiary public psychiatric hospital. The primary outcome was individual differences in plasma clozapine levels between before and after the smoking ban, which were compared using paired t-tests. The mean plasma clozapine level was significantly increased, by 213.4 ng/mL (95% CI 119.9-306.8; p<0.01) or 53.2%. Four of the 14 inpatients experienced clinically significant side effects, such as myoclonus, drooling, and amnesia, due to the development of high plasma clozapine levels. Our findings indicated that close monitoring of plasma clozapine levels before and after smoking cessation and prior dose adjustment of clozapine may be necessary, to prevent a significant risk of developing high plasma clozapine levels, even in Japanese patients.
Keywords Asian clozapine schizophrenia smoking
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 137
End Page 143
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503441
Web of Science KeyUT 000792374900005
JaLCDOI 10.18926/AMO/63406
FullText URL 76_2_129.pdf
Author Kubo, Kotaro| Nakamura, Keiichiro| Okamoto, Kazuhiro| Matsuoka, Hirofumi| Ida, Naoyuki| Haruma, Tomoko| Ogawa, Chikako| Masuyama, Hisashi|
Abstract Cancer patients have increased risk of venous thromboembolism (VTE) that must be assessed before treatment. This study aimed to determine effective VTE biomarkers in gynecologic cancer (GC). We investigated the correlation between D-dimer levels, Khorana risk score (KRS), Glasgow prognostic score (GPS), and VTE in 1499 GC patients (583 cervical cancer (CC), 621 endometrial cancer (EC), and 295 ovarian cancer (OC) patients) treated at our institution between January 2008 and December 2019. χ2 and Mann–Whitney U-tests were used to determine statistical significance. We used receiver operating characteristic-curve analysis to evaluate the discriminatory ability of each parameter. D-dimer levels were significantly correlated with KRS and GPS in patients with GC. VTE was diagnosed in 11 CC (1.9%), 27 EC (4.3%), and 39 OC patients (13.2%). Optimal D-dimer cut-off values for VTE were 3.1, 3.2, and 3.9 μg/ml in CC, EC and OC patients, respectively. D-dimer could significantly predict VTE in all GC patients. Furthermore, D-dimer combined with GPS was more accurate in predicting VTE than other VTE biomarkers in stage IIIC and IVA OC (AUC: 0.846; p<0.001). This study demonstrates that combined D-dimer and GPS are useful in predicting VTE in patients with OC.
Keywords D-dimer gynecologic cancer venous thromboembolism
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 129
End Page 135
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503440
Web of Science KeyUT 000792374900004
JaLCDOI 10.18926/AMO/63405
FullText URL 76_2_121.pdf
Author Okazaki, Yuki| Furumatsu, Takayuki| Hiranaka, Takaaki| Kamatsuki, Yusuke| Nakata, Eiji| Tetsunaga, Tomonori| Yamane, Kentaro| Ozaki, Toshifumi|
Abstract Bone marrow edema (BME) after meniscus injury and risk factors for subchondral insufficiency fracture of the knee (SIFK) have been reported. However, their association with medial meniscus posterior root tear (MMPRT) remains unknown. We investigated the association of BME volume (BME-V), posterior shinycorner lesion (PSCL), and SIFK with MMPRT to examine the correlations between BME-V and medial meniscus extrusion (MME), PSCL and duration from injury to the time of magnetic resonance imaging (duration), and SIFK and duration. Twenty-nine patients who underwent surgery for MMPRT were included (mean age, 59.2; range, 39-84). The presence of PSCL, femoral BME-V (cm3), and SIFK grade (1-4) were evaluated. Preoperative factors, such as MME (mm) and duration (weeks), were investigated using multivariate linear/ logistic regression analyses. Multivariate linear regression analysis revealed duration as a significant factor for high-grade SIFK (p<0.01). Multivariate logistic regression analysis revealed duration as a significant factor for the presence of PSCL (odds ratio=0.94, p<0.05). A long duration of MMPRT leads to severe MME and highgrade SIFK (3 and 4), often resulting in knee arthroplasty. Early diagnosis of MMPRT and pullout repair can prevent severe MME and high-grade SIFK.
Keywords medial meniscus posterior root tear subchondral insufficiency fracture bone marrow edema meniscus extrusion
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 121
End Page 127
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503439
Web of Science KeyUT 000792374900003
JaLCDOI 10.18926/AMO/63404
FullText URL 76_2_113.pdf
Author Namio, Keiichi| Miyatake, Nobuyuki| Hishii, Shuhei| Kondo, Takashi| Nishi, Hiroyuki| Katayama, Akihiko| Ujike, Kazuhiro| Koumoto, Kiichi| Suzuki, Hiromi| Hashimoto, Hiroo|
Abstract This study aimed to investigate the link between prolonged sedentary bouts and health-related quality of life (QOL) in patients on chronic hemodialysis (CHD). A total of 84 outpatients on CHD, aged 71.6±11.8 years, were enrolled in this cross-sectional study. Parameters for prolonged sedentary bouts [i.e., ≧ 30 min (% and bout) and ≧ 60 min (% and bout)] were measured using a triaxial accelerometer. Health-related QOL (HRQOL) was evaluated by the Euro-QOL (EQ-5D). Clinical parameters were obtained from medical records. Relatively prolonged sedentary bouts (%) were 44.0±18.2 (≧ 30 min) and 29.8±16.5 (≧ 60 min) for total days. Prolonged sedentary bouts (bouts) were 6.2±2.7 (≧ 30 min) and 2.7±1.6 (≧ 60 min) for total days. EQ-5D scores were 0.728±0.220. All prolonged sedentary bout parameters were negatively correlated with EQ-5D scores, except for prolonged sedentary bouts (≧ 60 min) (min) and relatively prolonged sedentary bouts (%) on hemodialysis days. Multiple regression analysis showed that prolonged sedentary bout parameters were an important factor in EQ-5D scores even after adjusting for confounding factors for total and non-hemodialysis days. Our results suggested that prolonged sedentary bouts were closely associated with HRQOL in patients on CHD, especially on non-hemodialysis days.
Keywords prolonged sedentary bouts hemodialysis EQ-5D QOL
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 113
End Page 119
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503438
Web of Science KeyUT 000792374900002
JaLCDOI 10.18926/AMO/63403
FullText URL 76_2_105.pdf
Author Takaoka, Megumi| Ohsumi, Shozo| Ikejiri, Haruka| Shidahara, Tomohiro| Miyoshi, Yuichiro| Takahashi, Mina| Takashima, Seiki| Aogi, Kenjiro|
Abstract Cases of breast cancer metastasis after achieving a pathological complete response (pCR) with neoadjuvant chemotherapy (NAC) are sometimes encountered in clinical practice. We investigated the prognostic factors for pCR in patients with breast cancer after NAC. This retrospective cohort study included patients with localized breast cancer who underwent NAC followed by surgery between 2004 and 2020 and achieved a pCR. The associations between clinical factors and distant metastasis-free survival rate were statistically analyzed. We analyzed data for 127 patients. Twelve patients (9.4%) had distant metastases, and seven (5.5%) died. For estrogen receptor (ER)-positive patients, the distant metastasis-free survival rate was 94.6% for both 5 and 8 years. In contrast, ER-negative patients had a distant metastasis-free survival rate of 87.6% and 85.4% for 5 and 8 years (p=0.094), respectively. In cT0-2 patients, the distant metastasis-free survival rate was 92.4% for 5 years and 90.5% for 8 years, whereas in cT3-4 patients, the distant metastasis-free survival rate was 83.5% for 5 years and 83.5% for 8 years (p=0.301). This study suggested that patients with ER-negative, pre-NAC cT3 or T4 breast cancer who had achieved a pCR after NAC tended to have a worse prognosis.
Keywords breast carcinoma neoadjuvant therapy prognosis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 105
End Page 111
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503437
Web of Science KeyUT 000792374900001
FullText URL 00-鹿田遺跡目次等.pdf 01-鹿田遺跡16 第1章.pdf 02-鹿田遺跡16 第2章.pdf 03-鹿田遺跡第3章.pdf 04-鹿田遺跡第4章.pdf 05-鹿田遺跡第5章.pdf 06-鹿田遺跡遺構一覧表.pdf 07-鹿田遺跡-図版.pdf 08-鹿田遺跡オルソ図版一覧表.pdf 09-鹿田遺跡報告抄録.pdf
Author Iwasaki, Shiho| 能城 修一| Oki, Yoko| 富岡 直人| (株)吉田生物研究所| パレオ・ラボAMS年代測定グループ|
Publication Title 岡山大学構内遺跡発掘調査報告
Published Date 2022-03-28
Volume volume38
language Japanese
File Version publisher
Pages 134p. 図版2枚, 50, 5p
FullText URL hss_053_contents_e.pdf
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
Title Alternative colophone
FullText URL hss_053_colophon.pdf
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
JaLCDOI 10.18926/63399
Title Alternative A Study of the "Scroll Painting of a Tale of Monsters" by Genki
FullText URL hss_053_(043).pdf
Author TSUTSUMI, Shoko|
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
Start Page (43)
End Page (61)
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
JaLCDOI 10.18926/63398
Title Alternative Japanese Translation of “Lunyu Jizhu”( 5)(Part 2) ― Xi ZHU’s Interpretation of “Confucian Analects” ―
FullText URL hss_053_(021).pdf
Author SUN, Luyi|
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
Start Page (21)
End Page (41)
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
JaLCDOI 10.18926/63397
Title Alternative A List of and Introduction to Asano Family Documents from Kasaoka Village, Oda District, Bicchu Province(1) : Economy, Distribution, Christianity
FullText URL hss_053_(001).pdf
Author HIGASHINO, Masanobu|
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
Start Page (1)
End Page (20)
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
JaLCDOI 10.18926/63396
Title Alternative Survey of Previous Studies on Husserl's Theory of the Other(2): Focusing on the Defense of Husserl
FullText URL hss_053_121.pdf
Author Satoh, Daisuke|
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
Start Page 121
End Page 141
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
JaLCDOI 10.18926/63395
Title Alternative The Factors of Tough Intransitive Verb Sentences in Japanese
FullText URL hss_053_109.pdf
Author SUN, Huixin|
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
Start Page 109
End Page 120
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
JaLCDOI 10.18926/63394
Title Alternative Analysis of Park Chung-hee's regime: Effect of the "Quasi-competitive System" on Constitutional Revision and the Yushin Regime, Part 2
FullText URL hss_053_089.pdf
Author LIM, chang yeon|
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
Start Page 89
End Page 108
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
JaLCDOI 10.18926/63393
Title Alternative On Sentences with a Predicate Composed of Word-Combinations of Sino-Japanese Verbal Nouns with Case-marker “wo” and “motarasu” in Japanese: From the Viewpoint of Voice
FullText URL hss_053_075.pdf
Author Wang, Dantong|
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
Start Page 75
End Page 88
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
JaLCDOI 10.18926/63392
Title Alternative Categorizing the Kindness Demanded by Friends, and Gender Differences ― A Preliminary Study with College Students ―
FullText URL hss_053_057.pdf
Author UCHIDA, Soma| Yamauchi, Hiroto|
Publication Title Journal of Humanities and Social Sciences
Published Date 2022-03-30
Volume volume53
Start Page 57
End Page 74
ISSN 1881-1671
language Japanese
Copyright Holders Copyright (c) 2022 岡山大学大学院社会文化科学研究科
File Version publisher
FullText URL fulltext.pdf
Author Matsuoka-Uchiyama, Natsumi| Uchida, Haruhito A.| Okamoto, Shugo| Onishi, Yasuhiro| Katayama, Katsuyoshi| Tsuchida-Nishiwaki, Mariko| Takeuchi, Hidemi| Takemoto, Rika| Hada, Yoshiko| Umebayashi, Ryoko| Kurooka, Naoko| Tsuji, Kenji| Eguchi, Jun| Nakajima, Hirofumi| Shikata, Kenichi| Wada, Jun|
Published Date 2022-01-10
Publication Title Journal Of Diabetes Research
Volume volume2022
Publisher Hindawi Ltd.
Start Page 3157841
ISSN 2314-6745
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Natsumi Matsuoka-Uchiyama et al.
File Version publisher
PubMed ID 35047644
DOI 10.1155/2022/3157841
Web of Science KeyUT 000774919000001
Related Url isVersionOf https://doi.org/10.1155/2022/3157841
FullText URL fulltext.pdf
Author Saito, Yukihiro| Nakamura, Kazufumi| Yoshida, Masashi| Sugiyama, Hiroki| Akagi, Satoshi| Miyoshi, Toru| Morita, Hiroshi| Ito, Hiroshi|
Keywords Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4 Human induced pluripotent stem cell-derived cardiomyocytes Pacing
Published Date 2022-04-01
Publication Title STEM Cell Research & Therapy
Volume volume13
Issue issue1
Publisher BMC
Start Page 141
ISSN 1757-6512
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 35365232
DOI 10.1186/s13287-022-02818-y
Web of Science KeyUT 000778298400007
Related Url isVersionOf https://doi.org/10.1186/s13287-022-02818-y