result 47919 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Uta, Daisuke| Oti, Takumi| Sakamoto, Tatsuya| Sakamoto, Hirotaka| |
| Keywords | in vivo extracellular recording in vivo whole-cell patch-clamp recording optogenetics spinal cord lamina X spinal ejaculation generator gastrin-releasing peptide neurons oxytocin |
| Published Date | 2021-03-26 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume22 |
| Issue | issue7 |
| Publisher | MDPI |
| Start Page | 3400 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 33810239 |
| DOI | 10.3390/ijms22073400 |
| NAID | 120007029875 |
| Web of Science KeyUT | 000638607100001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms22073400 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Kusumoto, Chiaki| Nakagawa, Masahiro| Kobayashi, Sayo| Yoshioka, Masao| Inaba, Tomoki| Toyokawa, Tatsuya| Hori, Shinichiro| Tanaka, Shouichi| Matsueda, Kazuhiro| Tanaka, Takehiro| Okada, Hiroyuki| |
| Published Date | 2021-04-01 |
| Publication Title | Scientific Reports |
| Volume | volume11 |
| Issue | issue1 |
| Publisher | Nature Research |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021 |
| File Version | publisher |
| PubMed ID | 33795810 |
| DOI | 10.1038/s41598-021-86893-w |
| NAID | 120007029876 |
| Web of Science KeyUT | 000636797900005 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-021-86893-w |
| JaLCDOI | 10.18926/AMO/61910 |
|---|---|
| FullText URL | 75_2_255.pdf |
| Author | Himemiya-Hakucho, Ayako| Fujimiya, Tatsuya| |
| Abstract | Alcohol has been identified as a potential precipitating factor for parasomnia, particularly sleepwalking (SW). We report an unusual case of a Japanese drunk driver who may have experienced alcohol-related SW, based on the statements of the suspect, pharmacokinetic analyses of the suspect’s breath alcohol concentration, testimonies of witnesses, driving recorder data, and medical records. The existence of sleep-related criminal acts performed while a suspect experiences memory loss under the influence of alcohol has not been sufficiently recognized, and awareness of such acts should be raised among the police, public prosecutors, and the general public in Japan. |
| Keywords | drunk driving sleepwalking parasomnia amnesia blood alcohol concentration |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 255 |
| End Page | 259 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953435 |
| NAID | 120007029877 |
| JaLCDOI | 10.18926/AMO/61909 |
|---|---|
| FullText URL | 75_2_249.pdf |
| Author | Sun, Weiying| Shiode, Yusuke| Tokumasu, Kazuki| Kimura, Shuhei| Hosokawa, Mio| Doi, Shinichiro| Takahashi, Kosuke| Matoba, Ryo| Otsuka, Fumio| Morizane, Yuki| |
| Abstract | A 79-year-old woman presented to our hospital with a 10-day history of gradually worsening binocular vision and severe backache. Further investigations revealed poor bilateral best-corrected visual acuities (BCVA), bilateral vitreous opacities, gray-white lesions scattered throughout the retina, and a left iliopsoas abscess on CT that later grew out methicillin-sensitive S. aureus. The abscess was drained and intravenous antibiotics were initiated, but the left eye additionally required intravitreal vancomycin. BCVA for both eyes normalized within 1 year. Intramuscular abscess should be considered as a possible primary lesion in cases of endogenous bacterial endophthalmitis. |
| Keywords | endogenous bacterial endophthalmitis methicillin-sensitive Staphylococcus aureus iliopsoas abscess intravitreal injection vancomycin |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 249 |
| End Page | 253 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953434 |
| NAID | 120007029878 |
| JaLCDOI | 10.18926/AMO/61908 |
|---|---|
| FullText URL | 75_2_243.pdf |
| Author | Tomita, Yusuke| Shimazu, Yosuke| Kawakami, Masato| Matsumoto, Hiroshi| Fujii, Kentaro| Kameda, Masahiro| Yasuhara, Takao| Suruga, Yasuki| Ota, Tomoyuki| Kimata, Yoshihiro| Kurozumi, Kazuhiko| Date, Isao| |
| Abstract | Ventriculitis is a rare, serious complication of neurosurgery. A 59-year-old man who had undergone a craniotomy for a paranasal adenocarcinoma, developed a right frontal cystic lesion. We performed a bifrontal craniotomy to remove the lesion. The dura was repaired with non-vascularized free fascia lata in watertight fashion. Ventriculitis occurred 3 days postoperatively. Ventricular drainage, craniectomy, and endoscopic irrigation were undertaken to remove an abscess. The dura and the resection cavity were reconstructed using a vascularized anterolateral thigh adipofascial flap. His symptoms disappeared, indicating that endoscopic irrigation and reconstruction can effectively address ventriculitis even in patients in critical clinical condition. |
| Keywords | ventriculitis surgical site infection intraventricular antimicrobial therapy anterior skull base surgery |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 243 |
| End Page | 248 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953433 |
| NAID | 120007029879 |
| JaLCDOI | 10.18926/AMO/61907 |
|---|---|
| FullText URL | 75_2_239.pdf |
| Author | Misawa, Haruo| Oda, Yoshiaki| Yamane, Kentaro| Tetsunaga, Tomoko| Ozaki, Toshifumi| |
| Abstract | One of the problems during surgery for intramedullary lipoma is the ambiguous boundary between the lipoma and the spinal cord, resulting in either incomplete resection or damage to the spinal cord. We report a case of intramedullary lipoma resection on a 61-year-old man in which the boundary between the tumor and spinal cord was repeatedly visualized with intraoperative ultrasonography. We focused on the distinctive features of fat as hyperechoic, in contrast to low-echo neural tissue. Subtotal resection of the tumor was achieved without any aggravation of neurological symptoms. Intraoperative ultrasonography may be useful for confirming tumor boundaries during intramedullary lipoma resection. |
| Keywords | intramedullary lipoma subtotal resection ultrasonography intraoperative guidance |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 239 |
| End Page | 242 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953432 |
| NAID | 120007029880 |
| JaLCDOI | 10.18926/AMO/61906 |
|---|---|
| FullText URL | 75_2_231.pdf |
| Author | Endo, Motochika| Yano, Shuya| Asano, Hiroaki| Takeda, Sho| Hamada, Yuki| Kondo, Yoshitaka| Kuroda, Shinji| Shigeyasu, Kunitoshi| Kikuchi, Satoru| Tanaka, Takehiro| Teraishi, Fuminori| Nishizaki, Masahiko| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Abstract | Targeted therapies for malignant melanoma have improved patients’ prognoses. A primary gastrointestinal malignant melanoma is very rare, with no standard treatment strategy. We treated a 78-year-old Japanese female with advanced primary gastrointestinal melanoma of the descending colon and gallbladder. We administered a multidisciplinary treatment: surgical resection of the descending colon and gallbladder tumors, resection of the metastatic lymph nodes behind the pancreas head, and immune checkpoint antibody-blockade therapy (nivolumab) for ~4 years. PET/CT demonstrated no recurrent lesion for > 3 years. Multidisciplinary therapies (e.g., surgery, chemotherapy, radiotherapy, target therapy, and immune checkpoint antibody-blockade therapy) can successfully treat primary gastrointestinal malignant melanoma. |
| Keywords | primary gastrointestinal melanoma laparoscopic surgery immune checkpoint antibody-blockade inhibitor |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 231 |
| End Page | 238 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953431 |
| NAID | 120007029881 |
| JaLCDOI | 10.18926/AMO/61905 |
|---|---|
| FullText URL | 75_2_225.pdf |
| Author | Xue, Haowei| Furumatsu, Takayuki| Okazaki, Yuki | Hiranaka, Takaaki| Kintaka, Keisuke | Zhang, Ximing| Yoshida, Aki| Ozaki, Toshifumi| |
| Abstract | A 65-year-old man presented with a left medial meniscus (MM) posterior root tear (PRT). Unicompartmental knee arthroplasty was performed 12 months after transtibial pullout repair of the MMPRT. Repaired MM posterior root tissue was subjected to histological analysis. Immunostaining and picrosirius red staining showed sufficient deposition of type I collagen, and hematoxylin-eosin staining using a polarized microscope showed well-aligned fiber orientation in the repaired tissue. The repaired posterior root (post-transtibial pullout repair) showed mature and well-aligned ligament-like tissue. Preserving the MM posterior root remnant to mimic the original posterior root tissue might be useful when performing pullout repair. |
| Keywords | medial meniscus posterior root tear unicompartmental knee arthroplasty histological analysis case report |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 225 |
| End Page | 230 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953430 |
| NAID | 120007029882 |
| JaLCDOI | 10.18926/AMO/61904 |
|---|---|
| FullText URL | 75_2_219.pdf |
| Author | Sugiura, Hiroyuki| Nishimori, Hisakazu| Matsuoka, Hirofumi| Nakamura, Keiichiro| Fujii, Keiko| Fujii, Nobuharu | Matsuoka, Ken-ichi | Maeda, Yoshinobu| |
| Abstract | Acute promyelocytic leukemia (APL) is a hematological emergency that requires urgent intervention because of the high incidence of early hemorrhagic death. When patients with APL experience a synchronous solid organ tumor, the tumor’s treatment must also be done properly. Differentiation-inducing therapy using arsenic trioxide (ATO) has less hematological toxicity compared to cytotoxic chemotherapy and might be preferable for untreated APL patients with a synchronous solid organ tumor. Here we describe the first successful case of untreated APL and synchronous endometrial cancer (in an adult Japanese woman) treated with ATO consolidation therapy and the subsequent surgery and chemotherapy for endometrial cancer. |
| Keywords | acute promyelocytic leukemia endometrial cancer arsenic trioxide synchronous multiple primary malignant tumor chemotherapy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 219 |
| End Page | 224 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953429 |
| NAID | 120007029883 |
| JaLCDOI | 10.18926/AMO/61903 |
|---|---|
| FullText URL | 75_2_213.pdf |
| Author | Miyashita, Manabi| Saragai, Yousuke| Fujimoto, Tsuyoshi| Tanaka, Shouichi| Aoki, Hideki| Sato, Yumiko | |
| Abstract | A 75-year-old Japanese man visited our hospital for further examination of liver tumors. He had a history of successful hepatitis C virus (HCV) eradication and therapy for hepatocellular carcinoma (HCC) at another hospital. Magnetic resonance imaging (MRI) revealed two tumors in the liver. He underwent anterior inferior (S5) and posterior inferior (S6) subsegmentectomy of the liver. Microscopic examination found that one tumor was HCC while the other was cholangiolocellular carcinoma (CoCC). We experienced a rare case of liver cancer with two synchronous pathologies, HCC and CoCC. |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 213 |
| End Page | 218 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953428 |
| NAID | 120007029884 |
| JaLCDOI | 10.18926/AMO/61902 |
|---|---|
| FullText URL | 75_2_205.pdf |
| Author | Hoshijima, Mitsuhiro| Kawanabe, Noriaki| Iida, Seiji| Yamashiro, Takashi| Kamioka, Hiroshi| |
| Abstract | We herein report the case of a 19-year-old female with a transverse discrepancy, skeletal Class II malocclusion, severe crowding with concerns of classic-type Ehlers-Danlos syndrome (EDS), aesthetics problems and functional problems. The main characteristics of classic EDS are loose-jointedness and fragile, easily bruised skin that heals with peculiar “cigarette-paper” scars. The anteroposterior and transverse skeletal discrepancies can generally be resolved by maxilla repositioning and mandibular advancement surgery following pre-surgical orthodontic treatment. However, this patient was treated with orthodontic camouflage but not orthognathic surgery because of the risks of skin bruising, poor healing and a temporomandibular disorder. A satisfactory dental appearance and occlusion were achieved after camouflage treatment with orthodontic anchor screws and the use of Class II elastics, including the preservation of the stomatognathic functions. Acceptable occlusion and dentition were maintained after a two-year retention period. This treatment strategy of orthodontic camouflage using temporary anchorage, such as anchor screws and Class II elastics, may be a viable treatment option for skeletal malocclusion patients with EDS. |
| Keywords | asymmetry Class II camouflage orthodontic anchor screw Ehlers-Danlos syndrome |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 205 |
| End Page | 212 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953427 |
| NAID | 120007029885 |
| JaLCDOI | 10.18926/AMO/61901 |
|---|---|
| FullText URL | 75_2_199.pdf |
| Author | Matsuda, Tatsuo| Umeda, Yuzo| Yoshida, Kazuhiro| Matsuda, Tadakazu| Uno, Masatoshi| Abe, Masaya| Asada, Noboru| Maeda, Yoshinobu| Yagi, Takahito| Fujiwara, Toshiyoshi| |
| Abstract | We present the first case of laparoscopic left lateral segmentectomy for hepatocellular carcinoma (HCC) in a patient with hemophilia A, acquired hepatitis C, and high-titer factor VIII inhibitor, which was confirmed by preoperative diagnosis. He underwent laparoscopic left lateral segmentectomy with the administration of recombinant activated factor VII. Surgery could be performed with reduced intraoperative hemorrhage. He experienced postoperative intra-abdominal wall hemorrhage, which was successfully managed with red cell concentrates transfusion and administration of recombinant activated factor VII. Laparoscopic hepatectomy can be applied for hemophilia patients with high titer inhibitors. |
| Keywords | hemophilia A hepatectomy inhibitor laparoscopy hepatocellular carcinoma |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 199 |
| End Page | 204 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953426 |
| NAID | 120007029886 |
| Author | Kunihiro, Tak| Ota, Tsutomu| Yamanaka, Masahiro| Nakamura, Eizo| |
|---|---|
| Published Date | 2021-05-17 |
| Content Type | Data or Dataset |
| JaLCDOI | 10.18926/61900 |
| FullText URL Alternative | https://dream.misasa.okayama-u.ac.jp/?q=20201021051740-459379| |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nakagawa, Ryo| Nishina, Yuta| |
| Keywords | redox potential phenazine mediator simulation DFT |
| Published Date | 2021-04-12 |
| Publication Title | Journal of Physics-Energy |
| Volume | volume3 |
| Issue | issue3 |
| Publisher | IOP Publishing Ltd |
| Start Page | 034008 |
| ISSN | 2515-7655 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Author(s). |
| File Version | publisher |
| DOI | 10.1088/2515-7655/abebc8 |
| NAID | 120007029887 |
| Web of Science KeyUT | 000639941800001 |
| Related Url | isVersionOf https://doi.org/10.1088/2515-7655/abebc8 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Okazaki, Yuki| Furumatsu, Takayuki| Hiranaka, Takaaki| Kintaka, Keisuke| Kodama, Yuya| Kamatsuki, Yusuke| Ozaki, Toshifumi| |
| Keywords | Anterior cruciate ligament Ramp lesion Risk factor Magnetic resonance imaging Proximal tibial geometry Medial tibial slope |
| Published Date | 2021-04 |
| Publication Title | Asia-Pacific Journal of Sport Medicine Arthroscopy |
| Volume | volume24 |
| Publisher | Elsevier Singapore Pte Ltd. |
| Start Page | 23 |
| End Page | 28 |
| ISSN | 2214-6873 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Asia Pacific Knee, Arthroscopy and Sports Medicine Society. |
| File Version | publisher |
| PubMed ID | 33680859 |
| DOI | 10.1016/j.asmart.2021.01.005 |
| NAID | 120007029888 |
| Web of Science KeyUT | 000636354300004 |
| Related Url | isVersionOf https://doi.org/10.1016/j.asmart.2021.01.005 |
| JaLCDOI | 10.18926/AMO/61897 |
|---|---|
| FullText URL | 75_2_187.pdf |
| Author | Fujiwara, Yuta| Sasaki, Tomoaki| Muto, Yuki| Hirano, Masaki| Kamizaki, Ryo| Murakami, Kaito| Miura, Naoya| Fujibuchi, Yutaka| Ohmukai, Nayu| Ueda, Nao | Sugimoto, Kouhei | Ota, Kazuhiro| Kamihoriuchi, Yoshiki| Sasaki, Tomoko| Kaneshige, Souichirou| |
| Abstract | The aim of this study is to evaluate how metallic artifacts in the lumbar spine can affect images obtained from magnetic resonance (MR) sequences. We performed a phantom experiment by scanning an agar containing an orthopedic metallic implant using 64-channel multidetector row computed tomography (CT) and a 3-tesla MR unit. We compared the reproducibility in each measurement, enlargement or reduction ratio of the CT and MR measurements, and signal deviation in each voxel from the control. The reproducibility on CT and multiacquisition variable-resonance image combination selective (MAVRIC SL) was good, but that on the other MR sequences showed either fixed bias or proportional bias. The reduction ratios of the distance between the nails were significantly smaller in MAVRIC SL than in the other MR sequences after CT measurements (p<0.001, respectively). MAVRIC SL was able to reduce the metallic artifact, permitting observation of the tissue surrounding the metal with good reproducibility. |
| Keywords | metallic artifact reduction implant MAVRIC SL |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 187 |
| End Page | 197 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953425 |
| NAID | 120007029889 |
| JaLCDOI | 10.18926/AMO/61896 |
|---|---|
| FullText URL | 75_2_169.pdf |
| Author | Nakada, Tetsuya| Kataoka, Takahiro| Nomura, Takaharu| Shuto, Hina| Yano, Junki| Naoe, Shota| Hanamoto, Katsumi| Yamaoka, Kiyonori| |
| Abstract | The forced swim test (FST) induces immobility in mice. Low-dose (high-dose-rate) X-irradiation inhibits FSTinduced immobility in mice due to its antioxidative function. We evaluated the effects of low-dose γ-irradiation at a low-dose-rate on the FST-induced depletion of antioxidants in mouse organs. Mice received whole-body low-dose-rate (0.6 or 3.0 mGy/h) of low-dose γ-irradiation for 1 week, followed by daily FSTs (5 days). The immobility rate on day 2 compared to day 1 was significantly lower in the 3.0 mGy/h irradiated mice than in sham irradiated mice. The FST significantly decreased the catalase (CAT) activity and total glutathione (t-GSH) content in the brain and kidney, respectively. The superoxide dismutase (SOD) activity and t-GSH content in the liver of the 3.0 mGy/h irradiated mice were significantly lower than those of the non-FST-treated mice. The CAT activity in the lungs of mice exposed to 3.0 mGy/h γ-irradiation was higher than that of non-FST treated mice and mice treated with FST. However, no significant differences were observed in the levels of these antioxidant markers between the sham and irradiated groups except for the CAT activity in lungs. These findings suggest that the effects of low-dose-rate and low-dose γ-irradiation on FST are highly organ-dependent. |
| Keywords | low-dose-rate γ-irradiation forced swim test antioxidant oxidative stress |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 169 |
| End Page | 175 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953424 |
| NAID | 120007029890 |
| JaLCDOI | 10.18926/AMO/61895 |
|---|---|
| FullText URL | 75_2_177.pdf |
| Author | Inoue, Madoka| Noda, Tomoyuki| Uehara, Takenori| Tetsunaga, Tomonori| Yamada, Kazuki| Saito, Taichi| Shimamura, Yasunori| Yamakawa, Yasuaki| Ozaki, Toshifumi| |
| Abstract | This retrospective study sought to elucidate the incidence rates of roof impaction (RI) and marginal impaction (MI) and radiological and clinical outcomes of open reduction and internal fixation (ORIF) for RI and MI in geriatric acetabular fractures. The cases of 68 patients aged ≥ 65 years (mean 71 years) treated with ORIF were analyzed. MI was present in 12 fractures (67%) and an RI of the weight-bearing surface was present in 24 (46%) of the potential fracture types. Regarding the reduction quality, 54% of the reductions were graded as anatomical, 37% as imperfect, and 9% as poor. In the clinical evaluations of the 45 patients who had > 1-year follow-up (follow-up rate: 66.2%), 18% were graded as excellent, 53% as good, 16% as fair, and 13% as poor. An anatomic reduction was strongly associated with good or excellent clinical and radiological outcomes. CT was superior to radiographs for detecting the residual displacement postoperatively. Postoperative deep infection occurred in four patients. Three patients (6.7%) underwent a total hip arthroplasty conversion due to secondary osteoarthritis of the hip. We recommend ORIF as the preferred surgical treatment option for displaced acetabular fractures in elderly patients. |
| Keywords | acetabular fracture osteosynthesis marginal impaction roof impaction elderly patient |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 177 |
| End Page | 185 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953423 |
| NAID | 120007029891 |
| JaLCDOI | 10.18926/AMO/61894 |
|---|---|
| FullText URL | 75_2_153.pdf |
| Author | Shimaoka, Shigeyoshi| Hamaoka, Hitomi| Inoue, Junji| Asanuma, Masato| Tooyama, Ikuo| Kondo, Yoichi| |
| Abstract | Lactoferrin (Lf) is an iron-binding glycoprotein mainly found in exocrine secretions and the secondary granules of neutrophils. In the central nervous system (CNS), expression of the Lf protein has been reported in the lesions of some neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, as well as in the aged brain. Lf is primarily considered an iron chelator, protecting cells from potentially toxic iron or iron-requiring microorganisms. Other biological functions of Lf include immunomodulation and transcriptional regulation. However, the roles of Lf in the CNS have yet to be fully clarified. In this study, we raised an antiserum against mouse Lf and investigated the immunohistochemical localization of Lf-like immunoreactivity (Lf-LI) throughout the CNS of adult mice. Lf-LI was found in some neuronal populations throughout the CNS. Intense labeling was found in neurons in the olfactory systems, hypothalamic nuclei, entorhinal cortex, and a variety of brainstem nuclei. This study provides detailed information on the Lf-LI distribution in the CNS, and the findings should promote further understanding of both the physiological and pathological significance of Lf in the CNS. |
| Keywords | lactoferrin immunohistochemistry brain mapping |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 153 |
| End Page | 167 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953422 |
| NAID | 120007029892 |
| FullText URL | interdisciplinary_1_colophon.pdf |
|---|---|
| Publication Title | Interdisciplinary Science |
| Published Date | 2021-03-31 |
| Volume | volume1 |
| ISSN | 2436-3227 |
| language | Japanese |
| File Version | publisher |
