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JaLCDOI 10.18926/AMO/71341
FullText URL 80_5_317.pdf
Author Saito, Hayato| Fukui, Ryohei| Sugihara, Hanako| Tada, Akihiro| Nagao, Shoji| Iguchi, Toshihiro|
Abstract This study evaluated the feasibility of predicting pathogenic BRCA1/2 variants in ovarian cancer using radiogenomic analysis of contrast-enhanced MRI. Twenty six patients were analyzed, including 14 with pathogenic BRCA1/2 variants and 12 without. Contrast enhanced MRI was used to generate two dimensional (2D) and three dimensional (3D) tumor segmentations. Radiomic features extracted with PyRadiomics were reduced using least absolute shrinkage and selection operator (LASSO) regression, yielding two selected features. Linear discriminant analysis (LDA) models were trained on 18 patients and tested on 8, with performance assessed using sensitivity, specificity, accuracy, and the area under the receiver operating characteristic (ROC) curve. The DeLong test compared AUCs between segmentation methods. Automated machine learning (AutoML) was performed with a training set of 20 patients and a test set of 6, with multiple performance metrics calculated. LDA achieved approximately 60% accuracy in both 2D and 3D test datasets. AUCs were 0.80 (3D) and 0.77 (2D), with no significant difference (p=0.85). AutoML identified CatBoost_BAG_L2_FULL as the optimal model, achieving accuracy above 80%. MRI-based radiogenomic analysis demonstrated moderate classification performance for identifying pathogenic BRCA1/2 variants in ovarian cancer. These preliminary findings suggest a potential role for noninvasive prediction, warranting further validation in larger cohorts.
Keywords ovarian cancer BRCA1/2 radiogenomics machine learning MRI
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 317
End Page 325
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71339
FullText URL 80_5_299.pdf
Author Xu, Tao| Zheng, Ying| Huang, Xuemei| Luo, Hong|
Abstract This study evaluated the prognostic significance of the C-reactive protein–albumin–lymphocyte (CALLY) index and systemic immune-inflammation (SII) index in predicting postoperative outcomes in patients with esophageal squamous cell carcinoma (ESCC). A retrospective analysis was performed on clinical data from 102 patients with ESCC who underwent surgical resection at Western Theater General Hospital of China between January 2020 and July 2023. The associations between preoperative CALLY and SII indices and relapse-free survival (RFS) and overall survival (OS) were examined. Survival curves were generated using the Kaplan–Meier method, and prognostic factors were identified using Cox proportional hazards regression analysis. Patients with a high CALLY index had significantly longer RFS (HR=0.30, 95% CI: 0.13-0.71), and those with a low SII index also had significantly longer RFS (HR=2.23, 95% CI: 1.12-4.41). Similarly, patients with a high CALLY index had significantly longer OS (HR=0.27, 95% CI: 0.13-0.55), and those with a low SII index had significantly longer OS (HR=2.27, 95% CI: 1.09-4.71). When patients were stratified into four groups, the low-CALLY–high-SII group showed significantly shorter RFS than the high-CALLY–low-SII group (HR=0.26, 95% CI: 0.11-0.61; p=0.013), and OS was also significantly worse in the low-CALLY–high-SII group (HR=0.22, 95% CI: 0.09-0.54; p=0.016). Univariate Cox regression analysis identified both CALLY and SII as significant prognostic factors. In multivariate analysis, the CALLY index and N stage were independently associated with RFS, whereas only tumor size remained independently associated with OS. The combined assessment of preoperative CALLY and SII indices may be useful for prognostic stratification in patients with ESCC undergoing upfront surgical resection. It may help identify high-risk patient subgroups with distinct survival outcomes, thereby providing a potential rationale for stratifying postoperative surveillance and tailoring individualized adjuvant strategies, although validation in larger prospective cohorts is warranted.
Keywords CALLY index SII index esophageal squamous cell carcinoma prognosis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 299
End Page 308
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71336
FullText URL 80_5_271.pdf
Author Sato, Ryosuke| Matsumoto, Kazuyuki| Otsuka, Motoyuki|
Abstract Peroral cholangioscopy (POCS) enables direct intraductal visualization and targeted biopsies for indeterminate biliary strictures. However, its diagnostic performance remains operator-dependent and is limited by sampling error. As artificial intelligence (AI) has rapidly advanced in gastrointestinal endoscopy, AI-assisted cholangioscopy has progressed from proof-of-concept image classification to multicenter validation, feature detection, and real-time application. Recent studies using digital single-operator cholangioscopy have reported diagnostic accuracy comparable to that of experts in differentiating malignant from benign strictures, and feature-based approaches can automatically detect tumor vessels and other key visual characteristics. Beyond classification, generative models may enhance mucosal and margin visualization through virtual chromoendoscopy, potentially improving lesion-margin assessment. Furthermore, new models compatible with multiple systems are emerging to address device heterogeneity, which is a key barrier to routine practice. This review summarizes the current evidence on AI-assisted POCS, discusses practical considerations for clinical translation, and highlights future directions, including real-time integration and multimodal decision support.
Keywords peroral cholangioscopy artificial intelligence biliary stricture deep learning virtual chromoendoscopy
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 271
End Page 277
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
Author Mimura, Souta| Kanda, Takefumi| Yamaguchi, Daisuke| Kubo, Kazuki| Wakimoto, Shuichi|
Note This is an Accepted Manuscript of an article published by IOP Publishing.| This fulltext file will be available in Apr. 2027.|
Published Date 2026-04-06
Publication Title Japanese Journal of Applied Physics
Volume volume65
Issue issue7
Publisher IOP Publishing
Start Page 07SP13
ISSN 0021-4922
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Japan Society of Applied Physics.
File Version author
DOI 10.35848/1347-4065/ae5116
Web of Science KeyUT 001733382700001
Related Url isVersionOf https://doi.org/10.35848/1347-4065/ae5116
FullText URL fulltext.pdf
Author Higaki, Fumiyo| Hiramatsu, Masafumi| Yasuhara, Takao| Sasada, Susumu| Otani, Yoshihiro| Haruma, Jun| Inoue, Tomohiro| Morimitsu, Yusuke| Akagi, Noriaki| Matsui, Yusuke| Iguchi, Toshihiro| Hiraki, Takao|
Keywords Photon-counting detector CT Energy-integrating detector CT CT angiography Neuroimaging Spine
Published Date 2024-09-16
Publication Title Japanese Journal of Radiology
Volume volume43
Issue issue2
Publisher Springer Science and Business Media LLC
Start Page 143
End Page 151
ISSN 1867-1071
NCID AA12375935
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39283532
DOI 10.1007/s11604-024-01661-w
Web of Science KeyUT 001313551500001
Related Url isVersionOf https://doi.org/10.1007/s11604-024-01661-w
FullText URL fulltext.pdf
Author Takahama, Wataru| Otsuka, Kosei| Ishihara, Ayumi| Hojo, Rikuto| Mogami, Tomofumi| Toyoda, Kazuhiro| Suzuki, Kohtaku| Takahashi, Yasushi|
Keywords photonic crystal waveguides potential sensors radiation-tolerant sensors space silicon photonics spacecrafts charging
Published Date 2026-09
Publication Title Advanced Sensor Research
Volume volume5
Issue issue9
Publisher Wiley
Start Page e70208
ISSN 2751-1219
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
DOI 10.1002/adsr.70208
Related Url isVersionOf https://doi.org/10.1002/adsr.70208
FullText URL fulltext.pdf
Author Suzuki, Etsuji|
Keywords attributable fraction causal inference confounding counterfactual model covariate balance etiologic fraction mediation sufficient cause model
Published Date 2025
Publication Title JMA Journal
Volume volume8
Issue issue2
Publisher Japan Medical Association
Start Page 323
End Page 337
ISSN 2433-3298
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Japan Medical Association
File Version publisher
PubMed ID 40416012
DOI 10.31662/jmaj.2024-0246
Web of Science KeyUT 001473764500001
Related Url isVersionOf https://doi.org/10.31662/jmaj.2024-0246
FullText URL fulltext.pdf
Author Yanagihara, Tsubasa| Shoji, Ryohei| Yoshida, Yusuke| Kanaya, Nobuhiko| Matsumi, Yuki| Shigeyasu, Kunitoshi| Kondo, Yoshitaka| Fujiwara, Toshiyoshi|
Keywords Hartmann’s reversal single-incision laparoscopic surgery parastomal hernia perioperative anaphylaxis chlorhexidine allergy
Published Date 2026
Publication Title Surgical Case Reports
Volume volume12
Issue issue1
Publisher Japan Surgical Society
Start Page cr.26-0206
ISSN 2198-7793
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
DOI 10.70352/scrj.cr.26-0206
CRID 1390590226643700736
Web of Science KeyUT 001814129200001
Related Url isVersionOf https://doi.org/10.70352/scrj.cr.26-0206
FullText URL fulltext.pdf
Author Kobayashi, Yasuyuki| Sano, Shunji| Tokuda, Yuhei| Kimura, Ayari| Staffa, Steven J.| Zurakowski, David| Kasahara, Shingo| Kotani, Yasuhiro|
Keywords asplenia syndrome atrioventricular valve regurgitation heterotaxy pulmonary atresia total anomalous pulmonary vein
Published Date 2026-02-03
Publication Title Journal of the American Heart Association
Volume volume15
Issue issue3
Publisher Ovid Technologies (Wolters Kluwer Health)
Start Page e044756
ISSN 2047-9980
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 41614290
DOI 10.1161/jaha.125.044756
Web of Science KeyUT 001679128200001
Related Url isVersionOf https://doi.org/10.1161/jaha.125.044756
FullText URL fulltext.pdf
Author Kondo, Ryoji| Ohashi, Kazuhito|
Keywords machine tool finite volume method temperature field thermal displacement real-time estimation
Published Date 2026-09-05
Publication Title International Journal of Automation Technology
Volume volume20
Issue issue5
Publisher Fuji Technology Press Ltd.
Start Page 466
End Page 477
ISSN 1883-8022
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Fuji Technology Press Ltd.
File Version publisher
DOI 10.20965/ijat.2026.p0466
Web of Science KeyUT 001868980600009
Related Url isVersionOf https://doi.org/10.20965/ijat.2026.p0466
Title Alternative Optimization of Smart Grid Operation Considering Diverse Electricity Consumption Patterns
FullText URL fultext_20260907-01.pdf
Author Kawamoto, Takaki| Toda, Yuriko| Hasuike, Takashi|
Keywords スマートグリッド (smart grid) マイクログリッド (microgrid) 再生可能エネルギー (renewable energy) 電力融通 (power interchange)
Note This is an Accepted Manuscript of an article published by 一般社団法人 電気学会.|
Published Date 2026-09-01
Publication Title IEEJ Transactions on Electronics, Information and Systems
Volume volume146
Issue issue9
Publisher 一般社団法人 電気学会
Start Page 864
End Page 876
ISSN 0385-4221
NCID AN10065950
Content Type Journal Article
language Japanese
OAI-PMH Set 岡山大学
Copyright Holders © 2026 電気学会
File Version author
DOI 10.1541/ieejeiss.146.864
Related Url isVersionOf https://doi.org/10.1541/ieejeiss.146.864
FullText URL fulltext.pdf
Author Tran, Thi Hai Yen| Kurita, Yoshihiko| Kondo, Maiko| Fukushima, Yosuke| Shigemitsu, Yusuke| Kawamoto, Yuya| Hara, Mayuko| Tsukahara, Hirokazu| Iwasaki, Tatsuo| Kasahara, Shingo| Baba, Kenji|
Keywords Fontan operation Spontaneous fenestration closure Fenestration recreation Longitudinal hemodynamic changes
Published Date 2026-05-09
Publication Title Pediatric Cardiology
Publisher Springer Science and Business Media LLC
ISSN 0172-0643
NCID AA00361536
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026
File Version publisher
PubMed ID 42105109
DOI 10.1007/s00246-026-04274-4
Web of Science KeyUT 001761259600001
Related Url isVersionOf https://doi.org/10.1007/s00246-026-04274-4
FullText URL fulltext.pdf
Author Matsuzaki, Kumiko| Matsuzaki, Hidenobu| Tabata, Tomoko| Aoyama, Hideki| Yoshio, Kotaro| Kosaki, Hirotaka| Ohara, Naoko| Sadr, Alireza| Soga, Yoshihiko| Shimada, Yasushi|
Keywords Radiation-induced caries Dental enamel Dentin Radiation effects Swept-source optical coherence tomography
Published Date 2026-07-11
Publication Title Scientific Reports
Volume volume16
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 22258
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026
File Version publisher
PubMed ID 42436170
DOI 10.1038/s41598-026-56971-y
Web of Science KeyUT 001822908900001
Related Url isVersionOf https://doi.org/10.1038/s41598-026-56971-y
Author Ichinose, Rikuto| Yamasaki, Shoei| Ishihara, Ayumi| Kanemaru, Yuta| Asano, Takashi| Noda, Susumu| Takahashi, Yasushi|
Abstract We demonstrated a Raman silicon nanocavity laser that enables wavelength conversion from the S-band to the L-band. Compared with Raman lasers operating from the E-band to the C-band, a degradation in lasing threshold was observed.
Published Date 2026
Publication Title CLEO 2026
Start Page FM4B.2
ISBN 9781957171586
language English
Copyright Holders © 2026 The Author(s)
File Version author
DOI 10.1364/cleo_fs.2026.fm4b.2
FullText URL fulltext.pdf
Author Furukawa, Saya| Yamamoto, Sakiya| Nakayama, Haruki| Ohashi, Ayaka| Satoh, Akira|
Keywords Molecular biology Evolutionary biology Developmental biology
Published Date 2026-06
Publication Title iScience
Volume volume29
Issue issue6
Publisher Elsevier BV
Start Page 116256
ISSN 2589-0042
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 42291206
DOI 10.1016/j.isci.2026.116256
Web of Science KeyUT 001794920600001
Related Url isVersionOf https://doi.org/10.1016/j.isci.2026.116256
JaLCDOI 10.18926/AMO/71070
FullText URL 80_4_259.pdf
Author Yabuno, Satoru| Yunoki, Masatoshi| Takeuchi, Saori| Hirashita, Koji|
Abstract Diffuse idiopathic skeletal hyperostosis (DISH) predisposes the spine to highly unstable fractures because of long lever-arm biomechanics. Unstable injuries, including AO Spine Osteoporotic Fracture (OF) type 5, are typically treated with long-segment posterior instrumentation; however, pedicle-screw fixation may be infeasible in very elderly patients with severe osteoporosis, critically narrow pedicles, and/or significant comorbidities. A 93-year-old Japanese woman presented with severe back pain without apparent trauma. Computed tomography (CT) revealed a T12 fracture with DISH, classified as OF5. The pedicles were critically narrow (3.7-4.1 mm), and dual-energy X-ray absorptiometry confirmed severe osteoporosis. Because conventional pedicle-screw fixation was considered technically unsafe and excessively invasive, limited posterior stabilization was performed using a single spinous process plate spanning T10-L1. The operative time was 48 min and the estimated blood loss was 10 ml. Immediate postoperative CT confirmed appropriate implant positioning and maintained alignment. At the 1-year follow-up, CT demonstrated solid bony union with preserved alignment and no implant failure; the patient had remained pain-free and ambulatory. This case demonstrates that spinous process-plate fixation can be a minimally invasive salvage option for carefully selected very-elderly patients with DISH when pedicle-screw instrumentation is not feasible.
Keywords DISH vertebral fracture osteoporosis spinous process plate
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-08
Volume volume80
Issue issue4
Publisher Okayama University Medical School
Start Page 259
End Page 264
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71067
FullText URL 80_4_241.pdf
Author Hasegawa, Yuta| Tsujimoto, Hironori| Uehata, Naoyuki| Kariya, Risa| Ide, Asuma| Suzuki, Takafumi| Fujishima, Seiichiro| Kouzu, Keita| Yaguchi, Yoshihisa| Miyai, Kosuke| Kurihara, Ayumu| Ogata, Sho| Matsukuma, Susumu| Ueno, Hideki|
Abstract Primary hyperparathyroidism (pHPT) is typically caused by a parathyroid adenoma, although some cases arise from ectopic glands. Accurate preoperative localization is essential for guiding surgical strategy, particularly for mediastinal lesions. We report successful video-assisted thoracoscopic surgery (VATS) for an upper mediastinal parathyroid adenoma. A 68-year-old woman was referred for hypercalcemia during evaluation for recurrent ureteral stones. Laboratory tests revealed elevated serum calcium (13.2 mg/dl) and intact parathyroid hormone (iPTH) levels (266 pg/ml). Contrast-enhanced computed tomography, magnetic resonance imaging, and 99mTc-methoxyisobutylisonitrile scintigraphy identified a 20-mm mass adjacent to the right esophageal wall. VATS was performed due to the tumor’s mediastinal location. The lesion was resected with intraoperative nerve monitoring (IONM) to avoid recurrent laryngeal nerve damage. Postoperatively, iPTH and calcium levels rapidly normalized. Transient hypocalcemia and mild hoarseness occurred but resolved with calcium supplementation and conservative management. Pathological examination confirmed a parathyroid adenoma without malignancy. VATS offers a safe and minimally invasive approach for upper mediastinal parathyroid adenomas. IONM and vigilant calcium management are crucial for minimizing these complications. This case highlights the importance of comprehensive imaging, surgical planning, and postoperative care in managing upper mediastinal pHPT.
Keywords primary hyperparathyroidism parathyroid neoplasm ectopic tissue video-assisted thoracoscopic surgery
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-08
Volume volume80
Issue issue4
Publisher Okayama University Medical School
Start Page 241
End Page 246
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
FullText URL fulltext.pdf
Author NEMOTO, Yuki| TANABE, Yoshinori| ONIZUKA, Ryouta| NAKAICHI, Munekazu|
Keywords feline Monte Carlo nasal lymphoma orthovoltage
Published Date 2026
Publication Title Journal of Veterinary Medical Science
Volume volume88
Issue issue8
Publisher Japanese Society of Veterinary Science
Start Page 1239
End Page 1245
ISSN 0916-7250
NCID AA10796138
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Japanese Society of Veterinary Science
File Version publisher
PubMed ID 42270411
DOI 10.1292/jvms.25-0305
CRID 1390027652838985984
Web of Science KeyUT 001839448400019
Related Url isVersionOf https://doi.org/10.1292/jvms.25-0305
FullText URL fulltext.pdf
Author Ida, Naoyuki| Nagao, Shoji| Fujikawa, Atsushi| Tanaka, Yui| Tanioka, Momoko| Imatani, Ryoko| Tani, Yoshinori| Sugihara, Hanako| Matsuoka, Hirofumi| Okamoto, Kazuhiro| Haraga, Junko| Ogawa, Chikako| Nakamura, Keiichiro| Masuyama, Hisashi|
Keywords anterolateral thigh flap extra-pelvic invasion gynecologic oncology low-grade serous ovarian carcinoma multidisciplinary surgery surgical limit
Published Date 2026-02-25
Publication Title Frontiers in Oncology
Volume volume16
Publisher Frontiers Media SA
Start Page 1762009
ISSN 2234-943X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 Ida, Nagao, Fujikawa, Tanaka, Tanioka, Imatani, Tani, Sugihara, Matsuoka, Okamoto, Haraga, Ogawa, Nakamura and Masuyama.
File Version publisher
PubMed ID 41821878
DOI 10.3389/fonc.2026.1762009
Web of Science KeyUT 001710573300001
Related Url isVersionOf https://doi.org/10.3389/fonc.2026.1762009
FullText URL fulltext.pdf
Author Kanaya, Nobuhiko| Kuroda, Shinji| Kakiutchi, Yoshihiko| Kashima, Hajime| Kikuchi, Satoru| Nishizaki, Masahiko| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Keywords gastric cancer long-term outcome prospective study robotic gastrectomy short-term outcome
Published Date 2025-02-15
Publication Title Cureus
Volume volume17
Issue issue2
Publisher Springer Science and Business Media LLC
Start Page e79063
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2025 Kanaya et al.
File Version publisher
PubMed ID 40104481
DOI 10.7759/cureus.79063
Related Url isVersionOf https://doi.org/10.7759/cureus.79063