result 4547 件
| Author | Fujikawa, Tatsuya| Shiraha, Hidenori| Yamamoto, Kazuhide| |
|---|---|
| Published Date | 2009-04-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume121 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/14842 |
|---|---|
| Title Alternative | The relationship between the magnetic resonance imaging of the lumbar spine and lowback pain |
| FullText URL | 72_066_070.pdf |
| Author | Takata, Shingo| Yokoi, Tadashi| Nishida, Norikazu| Okamoto, Makoto| Tsugeno, Hirofumi| Ashida, Kozo| Hosaki, Yasuhiro| Mifune, Takashi| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| Niiya, Kenji| Tanimoto, Mitsune| |
| Abstract | (目的) MRlは腰痛をきたす疾患の診断に必須な検査法である｡腰痛と腰椎MRl所見との関係を明らかにすることを目的として検討した｡(対象と方法)腰痛を訴えた30例を対象とし､腰椎MRl所見の頻度を調査した｡全例に温泉療法を施行した｡ (結果)全症例において腰椎MRl上異常所見を認めた｡少なくとも1つ以上の椎間板の変性病変をもつ症例は30例中27例(90% )で､椎間板変性はL4/5levelで最も多く認められた(30例中18例)｡椎間板ヘルニア を示す症例は30例中10例(33.3% )であった｡神経根圧迫を持つ症例は30例中8例(26.7% )であった｡腰椎圧迫骨折を持つ症例は30例中6例(20% )であった｡温泉療法により腰痛が改善した症例は30例中17例(56.7% )であった｡ (結論)腰痛症患者は腰椎MR止異常所見を有した｡温泉療法により腰痛の改善を認めたので､MRL上で認めた形態学的異常は必ずしも機能的異常や症状に直結しないと思われた｡ |
| Keywords | 腰痛症 (Disc disease) MRl (Magnetic resonance imaglng) 椎間板変性 (Lumbar spine) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 2002-02-01 |
| Volume | volume72 |
| Start Page | 66 |
| End Page | 70 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308103 |
| Author | A.I.. ABDUL| Murata, Atsuo| A.E. OLULEYE| |
|---|---|
| Published Date | 2008-12-11 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Ishii Masataka| Tanaka Yoshiyuki| Tsuji Toshio| Imamura Nobuaki| |
|---|---|
| Published Date | 2008-12-11 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Mehdi Eghbal| Yorino Naoto| Zoka Yoshifumi| |
|---|---|
| Published Date | 2008-12-11 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Hara Akira| Ichimura Takumi| |
|---|---|
| Published Date | 2008-12-11 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Matsubara, Fumie| Inoue, Taeko| 光延 彰子| Nagata, Takuya| Tanizaki, Yoshiro| |
|---|---|
| Published Date | 2004-02-01 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Volume | volume73 |
| Content Type | Data or Dataset |
| Author | Wang Shuguang| Murata, Atsuo| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Hanaa, E.Sayed| Hossam, A.Gabbar| Soheir, A. Fouadc| Khalil, M. Ahmedc| Miyazaki, Shigeji| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Handa, Hisashi| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| JaLCDOI | 10.18926/14784 |
|---|---|
| Title Alternative | 長期間の喫煙は高齢者気管支喘息における気道過敏性と関連した白血球LTB4産生を亢進させる |
| FullText URL | 74_018_025.pdf |
| Author | Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Iwagaki, Naofumi| Nagata, Takuya| Fujii, Makoto| Takata, Shingo| Yokoi, Tadashi| Hamada, Masanori| Tanizaki, Yoshiro| |
| Abstract | Abstract : Influence of cigarette smoking on leukotriene 84 (LTB4) generation by leucocytes associated with bronchial hyperresponsiveness was examined in 110 patients with asthma. l. The frequency of positive RAST score for inhalant allergens and LTB4 generation by leucocytes were significantly larger in previous and current smokers than in nonsmokers. 2. In nonsmokers, bronchial hyperresponsiveness was significantly higher in asthmatics under the age of 49 years compared with that in patients between 50 and 59 years, between 60 and 69 years, and those over age 70 years. In contrast, no significant differences were present between bronchial hyperresponsiveness and patient age in previous and current smokers. 3. In patients over age 60, bronchial hyperresponsiveness was significantly higher in previous and current smokers than in nonsmokers. In these patients, LTB4 generation was significantly more increased in previous and current smokers than in nonsmokers. 4. A significant correlation was observed in asthmatics of nonsmokers between LTB4 generation and bronchial hyperresponsiveness . 5. LTC4 generation was significantly higher in previous and current smokers than in nonsmokers in patients under age 49 years. These results show that in patients over age 60 years, cigarette smoking induces an increase in the generation of LTB4, leading to an increase in bronchial hyperresponsiveness . |
| Keywords | cigarette smoking asthma LTB4 generation LTC4 generation bronchial hyperresponsiveness |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2004-02-01 |
| Volume | volume74 |
| Start Page | 18 |
| End Page | 25 |
| ISSN | 1348-1258 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308359 |
| Author | Matsubara, Fumie| 光延 彰子| Nagata, Takuya| Tanizaki, Yoshiro| |
|---|---|
| Published Date | 2003-02-01 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Volume | volume73 |
| Content Type | Data or Dataset |
| JaLCDOI | 10.18926/14775 |
|---|---|
| Title Alternative | A case of anti - neutrophil cytoplasmic autoantibody-associated vasculitis: Resolution after early diagnosis |
| FullText URL | 73_088_092.pdf |
| Author | Ichikawa, Hirohisa| Ashida, Kozo| Ono, Katsuichiro| Takata, Shingo| Yokoi, Tadashi| Nagata, Takuya| Okamoto, Makoto| Tsugeno, Hirohumi| Nishida, Norikazu| Hosaki, Yasuhiro| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| Noguchi, Yoshinori| Tanimoto, Mitsune| |
| Abstract | 症例は76歳男性03年前肺気腫と診断された｡今回呼吸器リハビリテーション目的で当院に入院の運びとなった｡入院時より37-38'Cの発熱を認め,下気道感染を疑い抗生剤で加療したが改善しなかった.入院時の検尿検査で蛋白･潜血陽性であり,血清MPO-ANCAが307U/mlと高値を示した｡血清クレアチニン値も徐々に上昇してきたため,MPO-ANCA関連血管炎と診断した.プレドニゾロン投与を開始したところ,症状及び検査所見は速やかに改善した. |
| Keywords | ANCA関連血管炎 早期診断 顕微鏡的多発血管炎 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2003-02-01 |
| Volume | volume73 |
| Start Page | 88 |
| End Page | 92 |
| ISSN | 1348-1258 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308580 |
| JaLCDOI | 10.18926/14773 |
|---|---|
| Title Alternative | ’あくび’と胸痛を訴えた気管支喘息の1症例 |
| FullText URL | 73_081_083.pdf |
| Author | Mitsunobu, Fumihiro| Ashida, Kozo| Hosaki, Yasuhiro| Tsugeno, Hirofumi| Okamoto, Makoto| Nishida, Norikazu| Nagata, Takuya| Takata, Shingo| Tanizaki, Yoshiro| |
| Abstract | We present a case of a patient with asthma who developed yawning associated with anterior chest pain. She was admitted due to severe anterior chest pain, wheezing and dyspnea. Although the frequency of the symptoms decreased, she began to experience frequent episodes of yawning at night accompanied by tears. While she experienced yawning, although PEF (peak expiratory flow) decreased, no asthmatic symptoms, such as wheezing or dyspnea were observed. The yawning was improved markedly by bronchodilators and a leukotriene receptor antagonist, and moderately improved by corticosteroids. We speculated that yawning is a clinical manifestation of asthma that responds to treatment. |
| Keywords | yawning chest pain nocturnal dyspnea asthma |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2003-02-01 |
| Volume | volume73 |
| Start Page | 81 |
| End Page | 83 |
| ISSN | 1348-1258 |
| language | English |
| File Version | publisher |
| NAID | 120002308373 |
| JaLCDOI | 10.18926/14769 |
|---|---|
| Title Alternative | The level of plasma BNP continued remarkably high in the elderly presented with old myocardial infarction. |
| FullText URL | 73_064_071.pdf |
| Author | Nishida, Norikazu| Ashida, Kozo| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Tsugeno, Hirofumi| Okamoto, Makoto| Nagata, Takuya| Yokoi, Tadashi| Nakai, Mutsuo| Makino, Hirofumi| Tanizaki, Yoshiro| |
| Abstract | 心不全が比較的良好にコントロールされているのにもかかわらず,高齢の陳旧性心筋梗塞後患者等で脳性ナトリウム利尿ペプチド(BNP)の異常高値が持続する場合がある.今回,また超高齢の心不全患者で同所見を認めたので,考察を含めて報告する. 93歳高齢の陳急性心筋梗塞患者で,BNP1600-1200の著明な高値が持続した.主に心尖部と一部の前側壁の陳旧性心筋梗塞症であったが,利尿薬等による治療によって心不全はコントロールできており,救急入院時を除いては,鬱血性心不全の状態ではなかった.心願超音 波検査でも心内圧の上昇や下大静脈の拡張も認めなかった.利尿薬を増量するとむしろ脱水による腎機能障害の増悪を認めていた. 入院中に狭心痛を認めることがあり,心筋逸脱酔素の軽度の上昇を認めた.BNPの著明な高値持続は,陳旧性心筋梗塞後の心臓機能障害や左室肥大,僧帽弁閉頚不全等による慢性心不全･心負荷のための心筋でのBNP合成･分泌元進の他に,新たな小梗塞(非貫壁性心筋梗塞)や持続する無症候性の心筋虚血による心筋でのBNP合成･分泌亢進,高齢によるBNPクリアランスの低下と分泌の持続的亢進,慢性腎機能障害によるBNPクリアランスの低下,心筋障害後の心筋再構築(リモデリング)の訳節と心筋繊維化抑制の為に合成が元進していると考えられる.更に,いわゆる老人肺･慢性呼吸機能低下による右心系の負荷による心室からの分泌元進,ステロイドホルモン内服による鉱井コルチコイド作用,貧血,低栄養状態等の様々な要因が重なっているものと考えられた. 心臓でBNPの産生･分泌が亢進するのは,心不全に伴う全身の体液量バランスや血行動態等の悪化を改善,調節するためだけではなく,心臓自身のリモデリングの調節･抑制,再構築の調薪のため,さらには心臓･心筋の繊維化や拡張障害の増悪を抑制するための自己防衛 機構としても機能している.心臓は,単に循環系のポンプではなく,利尿ペプチドホルモンを分泌する内分泌器官でもある. 一般的に加齢に伴いBNPは上昇してくる.特に70歳以上の高齢者では顕著になる.考察ではその点についても新たな文献的考察も含めて報告し,高齢者のBNPの捉え方と治療についても述べる. |
| Keywords | bronchial asthma spa therapy perilla seed oil alpha -linolenic acid Leukotriene C4 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2003-02-01 |
| Volume | volume73 |
| Start Page | 64 |
| End Page | 71 |
| ISSN | 1348-1258 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308534 |
| JaLCDOI | 10.18926/14768 |
|---|---|
| Title Alternative | 気管支喘息に対する温泉療法とα-リノレン酸強化食の効果 |
| FullText URL | 73_055_063.pdf |
| Author | Okamoto, Makoto| Ashida, Kozo| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Tsugeno, Hirofumi| Nishida, Norikazu| Nagata, Takuya| Yokoi, Tadashi| Takata, Shingo| Tanizaki, Yoshiro| Tnimoto, Mitsune| |
| Abstract | N-3 fatty acids are reportedly effective for asthma. In addition, spa therapy has been reported to be effective for patients with asthma. In the present study, the effects of spa therapy combined with perilla seed oil- rich diet (rich in n-3 fatty acid)were examined on asthma. A total of 14 asthmatic patients had a complex spa therapy and consumed a perilla seed oil- rich diet - rich in a -linolenic acid (alpha-LNA) for 8 weeks. Generation of leukotriene (LT) C4 by leucocytes, respiratory function were analyzed. The generation of LTC4 by leucocytes decreased significantly for 2, 4 and 8 weeks (P |
| Keywords | bronchial asthma spa therapy perilla seed oil alpha -linolenic acid Leukotriene C4 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2003-02-01 |
| Volume | volume73 |
| Start Page | 55 |
| End Page | 63 |
| ISSN | 1348-1258 |
| language | English |
| File Version | publisher |
| NAID | 120002308428 |
| Author | Matsubara, Fumie| Inoue, Taeko| 光延 彰子| Takata, Shingo| Tanizaki, Yoshiro| |
|---|---|
| Published Date | 2004-12-01 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Volume | volume75 |
| Content Type | Data or Dataset |
| JaLCDOI | 10.18926/14752 |
|---|---|
| Title Alternative | アルルギー性鼻炎を合併したアトピー性喘息患者におけるロイコトリエン産生能と気道過敏性 |
| FullText URL | 075_037_044.pdf |
| Author | Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Iwagaki, Naofumi| Fujii, Makoto| Takata, Shingo| Hamada, Masanori| Tanizaki, Yoshiro| |
| Abstract | Rhinitis frequently precedes asthma, and treating allergic rhinitis has benefi-cial effects on asthma, suggesting upper airway disease ia a risk factor for asthma. The aim of the present study was to investigate the influence of allergic rhinitis on se-rum IgE level, leukotriene generation by peripheral leukocytes, and bronchial hyperresponsiveness (BHR) to methacholine in patients with atopic asthma. Seventy-one asthmatic subjects (mean age, 59.5±12.5, years ; 37 women, 34 men) were recruited, and 48 asthmatics had allergic rhinitis and 23 asthmatics did not have allergic rhinitis. The log10 (Dmin) was significantly lower for those with allergic rhinitis than those with-out allergic rhinitis (P<0.05), implying that those with allergic rhinitis developed BHR to a greater degree than those without allergic rhinitis. LTC4 generation from periph-eral leukocytes was significantly greater for atopic astmatics with allergic rhinitis than those without allergic rhinitis (p<0.05). In contrast, the amount of LTB4 produced from peripheral leukocytes did not significantly differ between asthmatic patients with and without allergic rhinitis. These results suggest that the presence of allergic rhinitis enhances BHR by enhancing LTC4 production. while the presence of allergic rhinitis did not affect LTB4 production in patients with atopic asthma. |
| Keywords | asthma (気管支喘息) allergic rhinitis (アレルギー性鼻炎) leukotriene generation (ロイコトリエン産性能) bronchial hyperresponsiveness (気道過敏性) |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2004-12-01 |
| Volume | volume75 |
| Start Page | 37 |
| End Page | 44 |
| ISSN | 1348-1258 |
| language | English |
| File Version | publisher |
| NAID | 120002308204 |
| Author | Yamashita, Hidetoshi| |
|---|---|
| Published Date | 1991 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume103 |
| Issue | issue11-12 |
| Content Type | Journal Article |
| Title Alternative | Toward Understanding of Regional Climate in East Asia around the Last Glacial Maximum with Attention to the Seasonal Cycle and Daily Meteorological Systems |
|---|---|
| FullText URL | erc_028_017_027.pdf |
| Author | Kato, Kuranoshin| Ikeda, Shoichiro| Abe, Kana| |
| Abstract | Regional climate system in East Asia shows the characteristic seasonal cycle affected by the Asian monsoon with various types of its sub-systems. The seasonal cycle there is also related greatly to behaviors of the frontal zones which are the boundaries of these sub-systems. Since the variation of global-scale environment such as the global warming influences on each monsoon sub-system in rather different manner, it is necessary to understand the joint effects of these subsystems, in order to predict the regional climate change in East Asia in the global warming. In such research, it would be also useful to examine the features in the ice age, as an opposite extreme situation against the global warming. Thus the present paper will discuss some viewpoints in investigating the regional climate in the Last Glacial Maximum with attention to the seasonal cycle and daily meteorological systems. |
| Keywords | Climate in East Asia Seasonal cycle Frontal zone Last Glacial Maximum |
| Publication Title | 環境制御 |
| Published Date | 2006-12 |
| Volume | volume28 |
| Start Page | 17 |
| End Page | 27 |
| ISSN | 0917-1533 |
| language | Japanese |
| File Version | publisher |
