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Title Alternative Questionnaire survey of junior and mid-career otolaryngologists' attitudes towards clinical research
Author Uraguchi, Kensuke| Yorifuji, Takashi| Takao, Soshi| Sugaya, Akiko| Ando, Mizuo|
Abstract  Introduction : Clinical research is crucial for the advancement of medicine, but modern otolaryngologists' attitudes regarding clinical research have not been known. This study was conducted to survey the background, knowledge, and interest in clinical research among junior and mid-career otolaryngologists.
 Methods : A questionnaire survey was distributed to 34 otolaryngologists with ≤15 years' clinical experience working at Okayama University and its affiliated facilities. The respondents were divided into junior (non-specialists) and mid-career otolaryngologists (specialists) based on whether they were board-certified otolaryngologists. The survey assessed their background, understanding, and interest in clinical research.
 Results : Twenty-nine otolaryngologists (83%) responded (10 junior and 19 mid-career otolaryngologists). There was significant individual variation in their interest and knowledge of clinical research. However, approximately half of the respondents indicated that they were not interested in and/or had never engaged in clinical research.
 Conclusion : The data collected by this survey contribute to our understanding of the current state of clinical research engagement among junior and mid-career otolaryngologists, and they can serve as a basis for exploring future strategies to increase this engagement.
Keywords 臨床研究 (clinical research) 統計解析 (statistical analysis) ビッグデータ (bigdata) 質問紙調査 (questionnaire survey)
Publication Title Journal of Okayama Medical Association
Published Date 2025-04-01
Volume volume137
Issue issue1
Start Page 20
End Page 24
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.137.20
language Japanese
Copyright Holders Copyright (c) 2025 岡山医学会
File Version publisher
DOI 10.4044/joma.137.20
Author Gonçalves, Bronner P.| Suzuki, Etsuji|
Keywords Causal inference Effect modification Principal stratification Transportability
Note This is a non-final version of an article published in final form in Gonçalves, Bronner P.a; Suzuki, Etsujib,c. Effect Modification in Settings with “Truncation by Death”. Epidemiology 36(3):p 374-380, May 2025. | DOI: 10.1097/EDE.0000000000001834.| This fulltext file will be available in May 2026.|
Published Date 2025-05
Publication Title Epidemiology
Volume volume36
Issue issue3
Publisher Ovid Technologies (Wolters Kluwer Health)
Start Page 374
End Page 380
ISSN 1044-3983
NCID AA10832184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 Wolters Kluwer Health, Inc.
File Version author
PubMed ID 39855255
DOI 10.1097/ede.0000000000001834
Web of Science KeyUT 001465446900002
Related Url isVersionOf https://doi.org/10.1097/ede.0000000000001834
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Obara, Takafumi| Hongo, Takashi| Nojima, Tsuyoshi| Tsukahara, Kohei| Hisamura, Masaki| Nakao, Atsunori| Yorifuji, Takashi| Naito, Hiromichi|
Keywords Ambulance diversion Bed occupancy Brain death Emergency medical services Intensive care units Organ donation
Published Date 2025-04-12
Publication Title Scientific Reports
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 12633
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40221631
DOI 10.1038/s41598-025-97198-7
Web of Science KeyUT 001466042000027
Related Url isVersionOf https://doi.org/10.1038/s41598-025-97198-7
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Obara, Takafumi| Hongo, Takashi| Iida, Atsuyoshi| Tsukahara, Kohei| Katsura, Morihiro| Kondo, Yutaka| Yasuda, Hideto| Kushimoto, Shigeki| Yorifuji, Takashi| Naito, Hiromichi| Nakao, Atsunori| SHIPPs Study Group|
Keywords Abdominal injuries Blood transfusions Hemoglobin Hemostasis Shock index
Published Date 2025-03-12
Publication Title Scientific Reports
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 8502
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40074821
DOI 10.1038/s41598-025-92673-7
Web of Science KeyUT 001443941100009
Related Url isVersionOf https://doi.org/10.1038/s41598-025-92673-7
JaLCDOI 10.18926/AMO/68363
FullText URL 79_1_059.pdf
Author Minakawa, Shun| Hirano, Masayuki| Takahashi, Kazuya| Imamura, Yuta| Watanabe, Takashi|
Abstract Intraorbital arteriovenous fistulas (IOAVFs) are rare vascular abnormalities. We describe a case of an IOAVF featuring a direct shunt between the accessory meningeal artery and the superior ophthalmic artery. A 55-year-old woman presented with a 1-month history of visual impairment in her right eye, and magnetic resonance imaging (MRI) revealed optic neuritis-like findings. Steroid pulse therapy temporarily resolved visual impairment. However, 1 month later, she experienced decreased visual acuity, ocular conjunctival hyperemia, edema, and a pulsatile murmur. Contrast-enhanced MRI and digital subtraction angiography revealed compression optic neuropathy due to an IOAVF. Following successful treatment with transarterial embolization, her symptoms disappeared.
Keywords intraorbital arteriovenous fistula compressive optic neuropathy accessory meningeal artery superior ophthalmic vein
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-02
Volume volume79
Issue issue1
Publisher Okayama University Medical School
Start Page 59
End Page 64
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40012161
Web of Science KeyUT 001440463800008
JaLCDOI 10.18926/AMO/68361
FullText URL 79_1_047.pdf
Author Kojima, Kazunori| Ujikawa, Takuya| Ono, Toshiro|
Abstract We assessed the immediate effects of a home-based rehabilitation (HBR) program on the balance performance and toe-grip strength of 29 older adults (mean±SD age of 75.1±9.9; 16 males, 13 females) who were participating in HBR services provided by Japan’s nursing care insurance system. Their toe-grip strength and balance performance were measured before and after the HBR program. The subjects’ toe-grip strength was significantly improved after the treatment. The subjects who had had a stroke showed a significant improvement after HBR. Contrarily, no significant difference was observed in the subjects’ functional reach results or their one-leg standing time. These results indicate that the exercise regimen provided in the HBR program led to increased excitability of motor units and immediately enhanced the subjects’ toe-grip strength.
Keywords home-based rehabilitation toe-grip strength balance performance
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-02
Volume volume79
Issue issue1
Publisher Okayama University Medical School
Start Page 47
End Page 50
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40012159
Web of Science KeyUT 001440463800006
JaLCDOI 10.18926/AMO/68355
FullText URL 79_1_021.pdf
Author Yamamoto, Yasuhiro| Haraguchi, Takafumi| Matsuda, Kaori| Okazaki, Yoshio| Kimoto, Shin| Tanji, Nozomu| Matsumoto, Atsushi| Kobayashi, Yasuyuki| Mimura, Hidefumi| Hiraki, Takao|
Abstract We developed a machine learning model for predicting prostate cancer (PCa) grades using radiomic features of magnetic resonance imaging. 112 patients diagnosed with PCa based on prostate biopsy between January 2014 and December 2021 were evaluated. Logistic regression was used to construct two prediction models, one using radiomic features and prostate-specific antigen (PSA) values (Radiomics model) and the other Prostate Imaging-Reporting and Data System (PI-RADS) scores and PSA values (PI-RADS model), to differentiate high-grade (Gleason score [GS] ≥ 8) from intermediate or low-grade (GS < 8) PCa. Five imaging features were selected for the Radiomics model using the Gini coefficient. Model performance was evaluated using AUC, sensitivity, and specificity. The models were compared by leave-one-out cross-validation with Ridge regularization. Furthermore, the Radiomics model was evaluated using the holdout method and represented by a nomogram. The AUC of the Radiomics and PI-RADS models differed significantly (0.799, 95% CI: 0.712-0.869; and 0.710, 95% CI: 0.617-0.792, respectively). Using holdout method, the Radiomics model yielded AUC of 0.778 (95% CI: 0.552-0.925), sensitivity of 0.769, and specificity of 0.778. It outperformed the PI-RADS model and could be useful in predicting PCa grades, potentially aiding in determining appropriate treatment approaches in PCa patients.
Keywords prostate cancer machine learning prostate Imaging-Reporting and Data System radiomics Gleason score
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-02
Volume volume79
Issue issue1
Publisher Okayama University Medical School
Start Page 21
End Page 30
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40012156
Web of Science KeyUT 001440463800003
FullText URL fulltext.pdf
Author Kobayashi, Yasuyuki| Sano, Shunji| Narumiya, Yuto| Kimura, Ayari| Suzuki, Etsuji| Kasahara, Shingo| Kotani, Yasuhiro|
Keywords Truncus arteriosus Staged repair Primary repair Pulmonary artery banding Risk stratification
Note The version of record of this article, first published in Pediatric Cardiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00246-025-03790-z|
Published Date 2025-01-30
Publication Title Pediatric Cardiology
Publisher Springer Science and Business Media LLC
ISSN 0172-0643
NCID AA00361536
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 39883183
DOI 10.1007/s00246-025-03790-z
Web of Science KeyUT 001409350800001
Related Url isVersionOf https://doi.org/10.1007/s00246-025-03790-z
FullText URL fulltext.pdf
Author Matsumoto, Naomi| Mitsui, Takashi| Tamai, Kei| Hirota, Tomoya| Masuyama, Hisashi| Yorifuji, Takashi|
Keywords Cesarean delivery Delivery methods Long-term outcome Child development Outcome-wide approach
Published Date 2025-01-20
Publication Title Scientific Reports
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 2485
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 39833288
DOI 10.1038/s41598-025-87043-2
Web of Science KeyUT 001402008500024
Related Url isVersionOf https://doi.org/10.1038/s41598-025-87043-2
FullText URL fulltext.pdf
Author Shigehara, Kenji| Matsumoto, Naomi| Tsuge, Mitsuru| Uda, Kazuhiro| Saito, Yukie| Yashiro, Masato| Yorifuji, Takashi| Ikeda, Masanori| Tsukahara, Hirokazu|
Keywords Allergic rhinitis Bronchial asthma Atopic dermatitis National cohort study Passive smoking
Note The version of record of this article, first published in Allergy, Asthma & Clinical Immunology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13223-025-00952-9|
Published Date 2025-01-16
Publication Title Allergy, Asthma & Clinical Immunology
Volume volume21
Issue issue1
Publisher BMC
Start Page 4
ISSN 1710-1492
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025.
File Version publisher
PubMed ID 39825417
DOI 10.1186/s13223-025-00952-9
Web of Science KeyUT 001397990900001
Related Url isVersionOf https://doi.org/10.1186/s13223-025-00952-9
FullText URL fulltext.pdf
Author Kitajima, Takuma| Hisamatsu, Takashi| Kanda, Hideyuki| Tabuchi, Takahiro|
Keywords cross-sectional survey heated tobacco products logistic regression nicotine dependence tobacco dependence screener
Published Date 2025-01-09
Publication Title Neuropsychopharmacology Reports
Volume volume45
Issue issue1
Publisher Wiley
Start Page e12512
ISSN 2574-173X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 39780643
DOI 10.1002/npr2.12512
Web of Science KeyUT 001391927500001
Related Url isVersionOf https://doi.org/10.1002/npr2.12512
Author Fukushima, Shinnosuke| Sumida, Takaomi| Kawamata, Osamu| Hidani, Yoshimi| Hagiya, Hideharu|
Keywords Global warming Japanese spotted fever Tick bite Tick-borne diseases
Note © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2026.|
Published Date 2024-12-02
Publication Title Journal of Infection and Chemotherapy
Volume volume31
Issue issue2
Publisher Elsevier
Start Page 102570
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 39631676
DOI 10.1016/j.jiac.2024.11.020
Web of Science KeyUT 001400947800001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2024.11.020
FullText URL fulltext.pdf
Author Nakamura, Naoko| Mitsuhashi, Toshiharu| Nakashima, Yasuko| Matsumoto, Naomi| Yorifuji, Takashi|
Keywords community health planning diagnostic screening programmes home visits postpartum depression postnatal care quasi-experimental study
Published Date 2023-07-19
Publication Title Family Practice
Publisher Oxford University Press (OUP)
Start Page cmad074
ISSN 1460-2229
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37467366
DOI 10.1093/fampra/cmad074
Web of Science KeyUT 001030159100001
Related Url isVersionOf https://doi.org/10.1093/fampra/cmad074
Title Alternative Effects of parity on the associations between evacuation and psychological distress and cardiovascular disease among women after the Great East Japan Earthquake : A cross-sectional study of the Fukushima Health Management Survey
Author Yasukawa, Sumiyo| Eguchi, Eri| Ohira, Tetsuya| Hayashi, Fumikazu| Sakai, Akira| Shimabukuro, Michio| Fujimori, Keiya| Miura, Itaru| Yabe, Hirooki| Maeda, Masaharu| Yasumura, Seiji|
Abstract  Introduction : Women are more likely to be physically, mentally, and socially vulnerable after disasters because of the physical, socioeconomical, and lifestyle-related factors that are often related to their parity. Here, we analyzed the effects of women's parity on the association between evacuation and psychological distress, trauma reactions, and cardiovascular disease (CVD).
 Participants and Methods : The participants were residents living in 13 municipalities in the evacuation zone of Japan's Fukushima Prefecture after the March 11, 2011 Great East Japan Earthquake who responded to the Fukushima Health Management Survey in FY2012. A total of 30,709 women aged 40-90 years were included in the analyses. We performed a logistic regression analysis to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) adjusted for CVD risk factors.
 Results : A multivariate analysis revealed that among the parous women (n = 19,608), evacuation was associated with psychological distress (adjusted OR 1.30, 95%CI : 1.17-1.44), trauma reactions (OR 1.22, 95%CI : 1.11-1.35), and heart disease (OR 1.14, 95%CI : 1.03-1.26) compared to the non-evacuation status. Among the nulliparous women (n = 1,794), there was no association between the evacuation and any outcomes.
 Conclusion : The evacuation of individuals after the Great East Japan Earthquake was associated with psychological distress, trauma reactions, and heart disease, especially among parous women.
Keywords 東日本大震災(the Great East Japan Earthquake) 大規模災害(large disaster) 出産歴(parity) 精神的苦痛(psychological distress) 循環器疾患(cardiovascular disease)
Publication Title Journal of Okayama Medical Association
Published Date 2024-12-02
Volume volume136
Issue issue3
Start Page 120
End Page 126
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.120
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.120
FullText URL fulltext.pdf
Author Akagi, Shinsuke| Takao, Soshi| Matsuo, Rumi| Matsumoto, Naomi| Yorifuji, Takashi|
Keywords all-cause mortality cardiovascular disease hypertension Japanese older adults survival analysis
Published Date 2024-12-12
Publication Title Geriatrics & Gerontology International
Volume volume25
Issue issue1
Publisher Wiley
Start Page 82
End Page 89
ISSN 1444-1586
NCID AA1155729X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version publisher
PubMed ID 39663894
DOI 10.1111/ggi.15046
Web of Science KeyUT 001374668300001
Related Url isVersionOf https://doi.org/10.1111/ggi.15046
FullText URL fulltext.pdf
Author Fukushima, Shinnosuke| Saito, Takashi| Iwamoto, Yoshitaka| Takehara, Yuko| Yamada, Haruto| Fujita, Koji| Yoshida, Masayo| Nakano, Yasuhiro| Hagiya, Hideharu|
Keywords Epidemiology Group A Streptococcus Necrotizing fasciitis Streptococcal toxic shock syndrome Surveillance
Note The version of record of this article, first published in European Journal of Clinical Microbiology & Infectious Diseases, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10096-024-05015-2|
Published Date 2024-12-16
Publication Title European Journal of Clinical Microbiology & Infectious Diseases
Publisher Springer Science and Business Media LLC
ISSN 0934-9723
NCID AA10686413
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39680263
DOI 10.1007/s10096-024-05015-2
Web of Science KeyUT 001378370400001
Related Url isVersionOf https://doi.org/10.1007/s10096-024-05015-2
JaLCDOI 10.18926/AMO/67877
FullText URL 78_6_469.pdf
Author Hirata, Yuichi| Nagase, Takayuki| Sasada, Susumu| Ayada, Yoshiyuki| Miyake, Hayato| Sugahara, Chiaki| Yamamoto, Hidetaka| Oda, Yoshinao| Yasuhara, Takao| Tanaka, Shota|
Abstract Tenosynovial giant cell tumor (TGCT) is a fibrous histiocytic tumor originating in the synovial membrane. While cervical TGCT may not be considered a common diagnosis preoperatively because it is relatively rare, it has a high recurrence rate and should be considered. Total resection is preferable, but it can be challenging due to the risk of damaging the vertebral artery. Denosumab has shown effectiveness as a postoperative treatment for osteolytic bone lesion. Denosumab administration coupled with close follow-up might offer an effective postoperative treatment option for unresectable TGCT with bone invasion.
Keywords tenosynovial giant cell tumor bone tumor spine
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-12
Volume volume78
Issue issue6
Publisher Okayama University Medical School
Start Page 469
End Page 474
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39719321
Web of Science KeyUT 001397269500003
JaLCDOI 10.18926/AMO/67872
FullText URL 78_6_459.pdf
Author Sakamoto, Shinya| Tabuchi, Motoyasu| Yoshimatsu, Rika| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro|
Abstract Traumatic neuroma is an abnormal proliferation of injured nerves resulting from trauma or surgery. We present a case of traumatic neuroma arising in the cystic duct after cholecystectomy. A 66-year-old man was referred to our department due to a biliary tumor. He had undergone cholecystectomy 20 years prior. Cholangioscopy showed an elevated lesion covered with smooth mucosa. Histological examination revealed normal bile duct mucosa. Although benign disease was suspected, the possibilities of malignant disease could not be excluded. Extrahepatic bile duct resection was planned to include intraoperative rapid-freezing of a biopsy specimen followed by histopathological examination. These intraoperative histology results showed proliferation of nerve and fibrous tissue only, resulting in the diagnosis of traumatic neuroma, so no lymph nodes were removed. To avoid excessive surgical intervention, histopathological examination of an intraoperative rapid-frozen biopsy specimen may be important for diagnosing traumatic neuroma.
Keywords traumatic neuroma biliary stricture cholecystectomy cholangiography intraoperative rapid-frozen biopsy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-12
Volume volume78
Issue issue6
Publisher Okayama University Medical School
Start Page 459
End Page 464
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39719319
Web of Science KeyUT 001397269500001
FullText URL fulltext.pdf
Author Matsumoto, Naomi| Mitsui, Takashi| Kadowaki, Tomoka| Mitsuhashi, Toshiharu| Hirota, Tomoya| Masuyama, Hisashi| Yorifuji, Takashi|
Keywords In vitro fertilization (IVF) Assisted reproductive technology (ART) Long-term outcome Development
Published Date 2024-11-18
Publication Title European Journal of Pediatrics
Volume volume184
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 24
ISSN 1432-1076
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39557744
DOI 10.1007/s00431-024-05883-y
Web of Science KeyUT 001363062300001
Related Url isVersionOf https://doi.org/10.1007/s00431-024-05883-y
FullText URL fulltext.pdf
Author Matsumoto, Naomi| Mitsuhashi, Toshiharu| Matsuo, Rumi| Kadowaki, Tomoka| Takao, Soshi| Yorifuji, Takashi|
Keywords COVID-19 Vaccine Omicron Prevention Pneumonia
Published Date 2023
Publication Title JMA Journal
Volume volume6
Issue issue4
Publisher Japan Medical Association
Start Page 463
End Page 469
ISSN 2433-3298
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Japan Medical Association
File Version publisher
PubMed ID 37941689
DOI 10.31662/jmaj.2023-0019
Web of Science KeyUT 001117541000004
Related Url isVersionOf https://doi.org/10.31662/jmaj.2023-0019