result 357 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Oti, Takumi| Satoh, Keita| Uta, Daisuke| Nagafuchi, Junta| Tateishi, Sayaka| Ueda, Ryota| Takanami, Keiko| Young, Larry J.| Galione, Antony| Morris, John F.| Sakamoto, Tatsuya| Sakamoto, Hirotaka| |
| Keywords | oxytocin localized volume transmission spinal cord male sexual activity gastrin-releasing peptide spinal ejaculation generator |
| Note | © 2020 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.cub.2020.09.089] .| |
| Published Date | 2020-10-29 |
| Publication Title | Current Biology |
| Volume | volume31 |
| Issue | issue1 |
| Publisher | Elsevier |
| Start Page | 103 |
| End Page | 114.e5 |
| ISSN | 0960-9822 |
| NCID | AA1081652X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| PubMed ID | 33125871 |
| DOI | 10.1016/j.cub.2020.09.089 |
| Related Url | isVersionOf https://doi.org/10.1016/j.cub.2020.09.089 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Katayama, Yukitoshi| Saito, Kazuhiro| Sakamoto, Tatsuya| |
| Keywords | stressors thirst angiotensin II corticosteroids amphibious fish |
| Published Date | 2020-09-14 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume21 |
| Issue | issue18 |
| Publisher | MDPI |
| Start Page | 6748 |
| ISSN | 1422-0067 |
| NCID | AA12038549 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by the authors. |
| File Version | publisher |
| PubMed ID | 32938015 |
| DOI | 10.3390/ijms21186748 |
| Web of Science KeyUT | 000580799600001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms21186748 |
| Author | Sakamoto, Syunya| |
|---|---|
| Published Date | 2013-05-03 |
| Publication Title | Multimedia and Ubiquitous Engineering |
| Content Type | Book |
| JaLCDOI | 10.18926/AMO/60808 |
|---|---|
| FullText URL | 74_5_455.pdf |
| Author | Yamanouchi, Kosho| Kuba, Sayaka| Matsumoto, Megumi| Yano, Hiroshi| Morita, Michi| Sakimura, Chika| Otsubo, Ryota| Kanetaka, Kengo| Nagayasu, Takeshi| Eguchi, Susumu| |
| Abstract | Taxanes are key drugs for patients with breast cancer. A major adverse effect associated with the administration of the taxane docetaxel is chemotherapy-induced peripheral neuropathy (CIPN). We are conducting a singlecenter, single-arm, open-label historical control trial to evaluate the ability of compression therapy using stockings or sleeves to prevent CIPN due to docetaxel treatment. The primary endpoint is the incidence of all-grade CIPN according to patients’ records until 3 weeks after the fourth docetaxel administration. This study’s results will clarify whether compression therapy using stockings or sleeves can prevent CIPN in breast cancer patients. |
| Keywords | breast cancer docetaxel neuropathy compression |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-10 |
| Volume | volume74 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 455 |
| End Page | 459 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33106704 |
| Web of Science KeyUT | 000581970100013 |
| NAID | 120006892934 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kawakami, Natsuko| Otubo, Akito| Maejima, Sho| Talukder, Ashraf H.| Satoh, Keita| Oti, Takumi| Takanami, Keiko| Ueda, Yasumasa| Itoi, Keiichi| Morris, John F.| Sakamoto, Tatsuya| Sakamoto, Hirotaka| |
| Keywords | copeptin hypothalamo‐pituitary–adrenal system immunohistochemistry paraventricular nucleus of the hypothalamus processing vasopressin RRID: AB_2722604 RRID: AB_2061966 RRID: AB_2314234 RRID: AB_10013361 RRID: AB_2313960 RRID: AB_2722605 RRID: AB_90782 |
| Published Date | 2020-09-06 |
| Publication Title | Journal of Comparative Neurology |
| Volume | volume529 |
| Issue | issue7 |
| Publisher | Wiley |
| Start Page | 1372 |
| End Page | 1390 |
| ISSN | 0021-9967 |
| NCID | AA00695917 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors. |
| File Version | publisher |
| PubMed ID | 32892351 |
| DOI | 10.1002/cne.25026 |
| Web of Science KeyUT | 000571267600001 |
| Related Url | isVersionOf https://doi.org/10.1002/cne.25026 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsutsui, Naoaki| Kobayashi, Yasuhisa| Izumikawa, Kouichi| Sakamoto, Tatsuya| |
| Keywords | peptide hormone Marsupenaeus japonicus ovary reproduction transcriptome vitellogenesis |
| Published Date | 2020-08-19 |
| Publication Title | Frontiers in Endocrinology |
| Volume | volume11 |
| Publisher | Frontiers Media |
| Start Page | 541 |
| ISSN | 1664-2392 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 Tsutsui, Kobayashi, Izumikawa and Sakamoto. |
| File Version | publisher |
| DOI | 10.3389/fendo.2020.00541 |
| Web of Science KeyUT | 000566191000001 |
| Related Url | isVersionOf https://doi.org/10.3389/fendo.2020.00541 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sakamoto, Yumi| Okui, Tatsuo| Yoneda, Toshiyuki| Ryumon, Shoji| Nakamura, Tomoya| Kawai, Hotaka| Kunisada, Yuki| Ibaragi, Soichiro| Masui, Masanori| Ono, Kisho| Obata, Kyoichi| Shimo, Tsuyoshi| Sasaki, Akira| |
| Keywords | Oral squamous cell cancer HMGB1 Bone destruction Osteoclasts |
| Published Date | 2020-10-20 |
| Publication Title | Biochemical and Biophysical Research Communications |
| Volume | volume531 |
| Issue | issue3 |
| Publisher | Elsevier |
| Start Page | 422 |
| End Page | 430 |
| ISSN | 0006-291X |
| NCID | AA00564395 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors |
| File Version | publisher |
| PubMed ID | 32800556 |
| DOI | 10.1016/j.bbrc.2020.07.120 |
| Web of Science KeyUT | 000571663900011 |
| Related Url | isVersionOf https://doi.org/10.1016/j.bbrc.2020.07.120 |
| JaLCDOI | 10.18926/AMO/60367 |
|---|---|
| FullText URL | 74_4_293.pdf |
| Author | Yoshioka, Takashi| Omae, Kenji| Kawada, Tatsushi| Inoue, Yosuke| Sugimoto, Morito| Oeda, Tadashi| Uehara, Shinya| Araki, Motoo| Fukuhara, Shunichi| |
| Abstract | In this retrospective single-center cohort study, we investigated the impact of preoperative use of an alpha-1 adrenergic receptor (AR) blocker on the outcome of single-session extracorporeal shock wave lithotripsy (SWL) in 193 male patients who underwent SWL for a single ureteral calculus between 2006 and 2016. We reviewed their medical records to obtain the data on the preoperative use of alpha-1 AR blockers. The primary outcome was treatment success after single-session SWL. We performed a multivariable logistic regression analysis adjusting for clinically important confounders to examine the association between preoperative use of alpha-1 AR blockers and the treatment success of SWL. Among the 193 patients, 15 (7.8%) were taking an alpha-1 AR blocker preoperatively. A multivariable analysis showed that preoperative use of an alpha-1 AR blocker was a significant negative predictor for treatment success of SWL (adjusted odds ratio 0.17; 95% confidence intervals, 0.04-0.74). Our findings suggest that the preoperative use of an alpha-1 AR blocker was a negative predictor of treatment success of SWL in male patients with a single ureteral calculus. Clinicians should pay more attention to the preoperative drug use in determining an appropriate stone therapy modality. |
| Keywords | urolithiasis extracorporeal shockwave therapy adrenergic alpha-1 receptor antagonists |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-08 |
| Volume | volume74 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 293 |
| End Page | 299 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32843760 |
| Web of Science KeyUT | 000562508700004 |
| NAID | 120006880206 |
| JaLCDOI | 10.18926/AMO/60364 |
|---|---|
| FullText URL | 74_4_275.pdf |
| Author | Muro, Taiko| Nakamura, Shinichiro| Takaki, Akinobu| Onishi, Hideki| Wada, Nozomu| Yasunaka, Tetsuya| Uchida, Daisuke| Oyama, Atsushi| Adachi, Takuya| Shiraha, Hidenori| Okada, Hiroyuki| |
| Abstract | Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) is a promising method for controlling tumors, although it does not entirely eliminate recurrence. Oxidative stress is associated with the progression of hepatocarcinogenesis, while also acting as an anticancer response. The objective of the present study was to investigate the factors influencing post-RFA outcomes. We recruited 235 newly diagnosed HCC patients who received RFA for single tumors. The patients with recurrence were sub-grouped into early and segmental recurrence groups. The characteristics of the sub-grouped patients were evaluated, including by measuring oxidative stress marker reactive oxygen metabolites and antioxidant marker OXY-adsorbent tests. The factors associated with poor survival were a high Child-Pugh score and early recurrence within 2 years in the same segment. The patients who experienced recurrence within 2 years in the same segment showed a larger tumor diameter than did others. According to a multivariate analysis, the OXY values were also significantly low in these patients. In conclusion, maintaining the antioxidant reservoir function with a high OXY value might be necessary to prevent early recurrence within the RFA-treated segment. |
| Keywords | oxidative stress hepatocellular carcinoma recurrence, radiofrequency ablation |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-08 |
| Volume | volume74 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 275 |
| End Page | 283 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32843758 |
| Web of Science KeyUT | 000562508700002 |
| NAID | 120006880203 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sakamoto, Junji| Tada, Naoya| Uemori, Takeshi| Kuniyasu, Hayato| |
| Keywords | nondestructive inspection crack detection low loading surface profile turbine blade finite element analysis |
| Published Date | 2020-07-16 |
| Publication Title | Applied Sciences |
| Volume | volume10 |
| Issue | issue14 |
| Publisher | MDPI |
| Start Page | 4883 |
| ISSN | 2076-3417 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by the authors. |
| File Version | publisher |
| DOI | 10.3390/app10144883 |
| Web of Science KeyUT | 000554160000001 |
| Related Url | isVersionOf https://doi.org/10.3390/app10144883 |
| FullText URL | Colloid_Surf_A_fulltext.pdf |
|---|---|
| Author | Watanabe, Takaichi| Sakamoto, Yui| Inooka, Tetsuya| Kimura, Yukitaka| Ono, Tsutomu| |
| Published Date | 2017-02-20 |
| Publication Title | Colloids and Surfaces A: Physicochemical and Engineering Aspects |
| Volume | volume520 |
| Publisher | Elsevier |
| Start Page | 764 |
| End Page | 770 |
| ISSN | 0927-7757 |
| NCID | AA10892561 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1016/j.colsurfa.2017.02.039 |
| Web of Science KeyUT | 000401401100085 |
| Related Url | isVersionOf https://doi.org/10.1016/j.colsurfa.2017.02.039 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Fa, Shixin| Yamamoto, Masanori| Nishihara, Hirotomo| Sakamoto, Ryota| Kamiya, Kazuhide| Nishina, Yuta| Ogoshi, Tomoki| |
| Published Date | 2020-06-01 |
| Publication Title | Chemical Science |
| Volume | volume11 |
| Issue | issue23 |
| Publisher | Royal Society of Chemistry |
| Start Page | 5866 |
| End Page | 5873 |
| ISSN | 2041-6539 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Royal Society of Chemistry 2020 |
| File Version | publisher |
| DOI | 10.1039/d0sc02422h |
| Web of Science KeyUT | 000544372300003 |
| Related Url | isVersionOf https://doi.org/10.1039/d0sc02422h |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ikeda, Tomoka| Gion, Yuka| Sakamoto, Misa| Tachibana, Tomoyasu| Nishikori, Asami| Nishimura, Midori Filiz| Yoshino, Tadashi| Sato, Yasuharu| |
| Keywords | Lymphoid tissues Lymphoma |
| Published Date | 2020-06-19 |
| Publication Title | Modern Pathology |
| Volume | volume33 |
| Issue | issue12 |
| Publisher | Springer Nature |
| Start Page | 2437 |
| End Page | 2448 |
| ISSN | 0893-3952 |
| NCID | AA1067307X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Authors |
| File Version | author |
| PubMed ID | 32561847 |
| DOI | 10.1038/s41379-020-0599-8 |
| Web of Science KeyUT | 000541317200003 |
| Related Url | isVersionOf https://doi.org/10.1038/s41379-020-0599-8 |
| JaLCDOI | 10.18926/AMO/59958 |
|---|---|
| FullText URL | 74_3_245.pdf |
| Author | Yamamoto, Shumpei| Takayama, Hiroshi| Shimodate, Yuichi| Takezawa, Rio| Nishimura, Naoyuki| Doi, Akira| Mouri, Hirokazu| Matsueda, Kazuhiro| Mizuno, Motowo| Okada, Hiroyuki| |
| Abstract | Antithrombotic therapy is a major risk factor for delayed bleeding after endoscopic submucosal dissection (ESD) for gastric neoplasia. A potassium-competitive acid blocker, vonoprazan, is expected to prevent delayed bleeding better than conventional proton pomp inhibitors (PPIs), but the evidence is controversial. We sought to clarify the efficacy of vonoprazan for prevention of delayed bleeding after gastric ESD in patients under antithrombotic therapy. We prospectively registered 50 patients who underwent gastric ESD while receiving antithrombotic therapy and vonoprazan in our institution between October 2017 and September 2018. The incidence of delayed bleeding was compared with that in a historical control group of 116 patients treated with conventional PPI. We also evaluated risk factors associated with delayed bleeding. Delayed bleeding was observed in 8 of 50 patients (16.0%), which was not dissimilar from the incidence in the historical control group (12.1%) (p=0.49). In the univariate analysis, age (> 70 years) (p=0.034), multiple antithrombotic drug use (p<0.01), procedure time (> 200 min) (p=0.038) and tumor size (> 40 mm) (p<0.01) were associated with delayed bleeding after gastric ESD, but vonoprazan was not (p=0.49). Vonoprazan may not be more effective than conventional PPIs in preventing delayed bleeding after gastric ESD in patients receiving antithrombotic therapy. |
| Keywords | vonoprazan endoscopic submucosal dissection antithrombotic drug gastric cancer |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-06 |
| Volume | volume74 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 245 |
| End Page | 250 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32577023 |
| Web of Science KeyUT | 000543363400008 |
| NAID | 120006862799 |
| JaLCDOI | 10.18926/AMO/59954 |
|---|---|
| FullText URL | 74_3_221.pdf |
| Author | Yagura, Takuma| Oe, Kenichi| Paku, Masaaki| Tajima, Takeshi| Nakamura, Masaya| Iida, Hirokazu| Saito, Takanori| |
| Abstract | We retrospectively evaluated the cases of 169 hip fracture patients, their previous fractures, and the contralateral hip joint’s morphology. A history of contralateral hip fracture was present in 23 patients (Contra group). The other patients had a unilateral hip fracture: a trochanteric fracture (Troch group, n=73) or a femoral neck fracture (Neck group, n=73). In the Troch and Neck groups, we used anteroposterior and cross-table axialview radiographs of the contralateral hip to evaluate the proximal femur’s anatomy. In the Contra group, the concordance rate between the first and second types of hip fracture was 65.2%, and the second hip fracture’s morphology indicated that the trochanteric fracture had a cam deformity in terms of the femoral head-neck ratio. The average alpha angle and femoral head-neck offset in the Troch group were significantly larger than those in the Neck group. In the Neck group, pistol-grip deformities of Arbeitsgemeinschaft für Osteosynthesefragen types B1 (subcapital), B2 (transcervical), and B3 (displaced) were observed in 42.1%, 75%, and 6% of cases, respectively. There was a smaller alpha angle and a larger femoral head-neck offset in the contralateral hip of femoral neck fractures; thus, the “cam deformity” may protect against femoral neck fractures. |
| Keywords | cam deformity femoral neck fracture trochanteric fracture bilateral hip fractures |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-06 |
| Volume | volume74 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 221 |
| End Page | 227 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32577020 |
| Web of Science KeyUT | 000543363400006 |
| NAID | 120006862796 |
| FullText URL | K0006111_abstract_review.pdf K0006111_summary.pdf K0006111_fulltext.pdf |
|---|---|
| Author | Sakamoto, Shuichi| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6111号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| JaLCDOI | 10.18926/AMO/58272 |
|---|---|
| FullText URL | 74_2_137.pdf |
| Author | Isozaki, Hiroshi| Yamamoto, Yasuhisa| Sakai, Kunihiko| Sho, Tatuo| Ishihara, Kiyohiro| Murakami, Shigeki| Matsumoto, Sasau| Takama, Takehiro| |
| Abstract | Mucinous carcinoma (MC) of the breast is a rare and special type of malignancy, with a substantial amount of extracellular mucin. We compared the clinicopathological features and the long-term survival of MC patients with those of invasive ductal carcinoma-no special type (IDC-NST) patients, and we examined prognostic factors of MC. A total of 116 patients with mucinous carcinoma and 3,258 patients with IDC-NST who underwent surgery at our hospital (1977-2008) were enrolled. The 10-year overall survival rate and breast cancer-specific survival rate (BSS) of the MC patients (88.3%, 93.7%) were both significantly higher than those of IDC-NST patients (81.6%, 85.0%) (p=0.015, p=0.005, respectively). A Cox regression analysis demonstrated that MC tended to be an independent prognostic factor (hazard ratio 0.44, p=0.098). The BSS of the MC patients with positive lymph node (LN) metastasis was significantly poorer than that of the patients without it, by univariate analysis (p=0.002). The tumor size in the MC patients with positive LN metastasis (mean 3.2 cm) was significantly larger than that in the patients without it (mean 1.9 cm) (p=0.0004). Although a Cox regression analysis revealed no independent factor, MC patients with positive LN metastasis should be treated for advanced invasive ductal breast cancer. |
| Keywords | breast cancer mucinous carcinoma clinicopathological features long-term prognosis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 137 |
| End Page | 143 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341588 |
| Web of Science KeyUT | 000528278500007 |
| NAID | 120006839451 |
| JaLCDOI | 10.18926/AMO/58269 |
|---|---|
| FullText URL | 74_2_115.pdf |
| Author | Kotani, Sayoko| Kamada, Yasuhiko| Shimizu, Keiko| Sakamoto, Ai| Nakatsuka, Mikiya| Hiramatsu, Yuji| Masuyama, Hisashi| |
| Abstract | Thrombosis in decidual vessels is one of the mechanisms of pregnancy loss. However, few studies have assessed the relation between platelet activation, which is known to cause of thrombosis, and recurrent pregnancy loss (RPL). We investigated platelet activation in women with RPL compared to controls by measuring plasma levels of platelet factor 4 (PF4) and β-thromboglobulin (βTG), and assessed correlations between PF4/βTG and coagulative risk factors associated with RPL. The study group included 135 women who had experienced two or more consecutive pregnancy losses. The control group included 28 age-matched healthy women who had never experienced pregnancy loss. PF4 and βTG plasma levels were significantly higher in the women with RPL than controls (PF4: 14.0 [8.0-20.0] vs. 9.0 [6.0-12.0] ng/ml, p=0.043; βTG: 42.0 [24.3-59.8] vs. 31.5 [26.6-36.4] ng/ml, p=0.002). There was a significant association between βTG and anti-phosphatidylethanolamine antibody immunoglobulin M (aPE IgM) (p=0.048). Among the women with RPL, 18 of those who were positive for PF4 (45%) and 18 of those who were positive for βTG (37%) were negative for all known coagulative risk factors associated with RPL. Measurements of PF4 and βTG may be important because they help identify women who are at risk of RPL. |
| Keywords | recurrent pregnancy loss platelet factor 4 β-thromboglobulin platelet activation |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 115 |
| End Page | 122 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341585 |
| Web of Science KeyUT | 000528278500004 |
| NAID | 120006839448 |
| JaLCDOI | 10.18926/AMO/58268 |
|---|---|
| FullText URL | 74_2_109.pdf |
| Author | Ogawa, Chikako| Nakamura, Keiichiro| Matsuoka, Hirofumi| Matsubara, Yuko| Haraga, Junko| Masuyama, Hisashi| |
| Abstract | This study aimed to determine whether the risk conferred by gynecologic cancer (GC) as second primary cancer (SPC) differs from that associated with GC as first primary cancer (FPC). We investigated the correlations between FPC/SPC and the characteristics and prognoses of 1,645 GC patients (701 with cervical cancer [CC], 641 with endometrial cancer [EM], and 303 with ovarian cancer [OV]). The χ2 test and the Kaplan–Meier method were used to determine whether FPC/SPC and the characteristics and prognoses of GC patients. Of the SPC patients, 26 (3.7%) had CC, 53 (8.3%) had EM, and 31 (10.2%) had OV. The most common previous cancer type in SPC of GC patients was breast cancer, which was observed in 13 patients (50.0%) with CC, 23 (43.4%) with EM, and 16 (51.6%) with OV. In all patients with CC, EM, and OV as SPC, the stage was significantly associated with recurrence. There were no significant differences in the morbidity or mortality of CC, EM, or OV patients between those with FPC and those with SPC. The risk of SPC development in GC patients varied, ranging from 3.5% (CC) to 10.3% (OV) of patients. |
| Keywords | second primary cancer gynecologic cancer prognosis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 109 |
| End Page | 114 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341584 |
| Web of Science KeyUT | 000528278500003 |
| NAID | 120006839447 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ueki, Yushi| Saito, Ken| Iioka, Hidekazu| Sakamoto, Izumi| Kanda, Yasuhiro| Sakaguchi, Masakiyo| Horii, Arata| Kondo, Eisaku| |
| Keywords | Cancer Molecular Biology |
| Published Date | 2020-01-18 |
| Publication Title | iScience |
| Volume | volume23 |
| Issue | issue2 |
| Publisher | Cell Press |
| Start Page | 100850 |
| ISSN | 25890042 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Author(s). |
| File Version | publisher |
| PubMed ID | 32058962 |
| DOI | 10.1016/j.isci.2020.100850 |
| Web of Science KeyUT | 000518637100047 |
| Related Url | isVersionOf https://doi.org/10.1016/j.isci.2020.100850 |
