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JaLCDOI 10.18926/AMO/64358
FullText URL 77_1_29.pdf
Author Yamamoto, Shusei| Sato, Ikumi| Fujii, Moe| Kakimoto, Mai| Honma, Koki| Akiyama, Natsumi| Sakai, Miku| Fukuhama, Natsuki| Kumazaki, Shota| Hirohata, Satoshi| Kitamori, Kazuya| Yamori, Yukio| Watanabe, Shogo|
Abstract The SHRSP5/Dmcr is a useful animal model for the development of nonalcoholic steatohepatitis (NASH) pathology when fed a high-fat, high-cholesterol diet, and further drug interventions can lead to concomitant cardiovascular disease. While SHRSP5/Dmcr rats have been used for basic research related to NASH, details of their bile acid metabolism in this condition are unknown. In this study, we aimed to clarify the changes in the serum bile acid (BA) fractions associated with NASH and found that glycine-conjugated and unconjugated bile acid increased with worsening NASH and cardiovascular disease while taurine-conjugated BA relatively decreased.
Keywords SHRSP5/Dmc nonalcoholic steatohepatitis cardiovascular disease glycine-conjugated bile acids unconjugated bile acids
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 29
End Page 36
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849143
Web of Science KeyUT 000953019200001
FullText URL fulltext.pdf
Author Takagi, Kosei| Umeda, Yuzo| Yoshida, Ryuichi| Fuji, Tomokazu| Yasui, Kazuya| Kimura, Jiro| Hata, Nanako| Yagi, Takahito| Fujiwara, Toshiyoshi|
Keywords pancreatoduodenectomy robotic surgery gastrojejunostomy delayed gastric emptying
Published Date 2023-01-16
Publication Title Journal Of Clinical Medicine
Volume volume12
Issue issue2
Publisher MDPI
Start Page 732
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 36675661
DOI 10.3390/jcm12020732
Web of Science KeyUT 000914818600001
Related Url isVersionOf https://doi.org/10.3390/jcm12020732
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Kono, Yoshiyasu| Kawano, Seiji| Okada, Horoyuki|
Keywords nivolumab ipilimumab immune -related adverse events immune checkpoint inhibitor esophagogastroduodenoscopy
Published Date 2022-12-19
Publication Title CUREUS JOURNAL OF MEDICAL SCIENCE
Volume volume14
Issue issue12
Publisher Cureus
Start Page e32710
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Iwamuro et al.
File Version publisher
PubMed ID 36686096
DOI 10.7759/cureus.32710
Web of Science KeyUT 000905471200003
Related Url isVersionOf https://doi.org/10.7759/cureus.32710
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Matsumura, Akifumi| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki|
Published Date 2022-12-31
Publication Title Case Reports In Gastrointestinal Medicine
Volume volume2022
Publisher Hindawi Ltd
Start Page 4637707
ISSN 2090-6528
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Masaya Iwamuro et al.
File Version publisher
PubMed ID 36624891
DOI 10.1155/2022/4637707
Web of Science KeyUT 000910999400001
Related Url isVersionOf https://doi.org/10.1155/2022/4637707
FullText URL fulltext.pdf
Author Ojima, Hinako| Kuraoka, Sakiko| Okanoue, Shyoutarou| Okada, Hiroyuki| Gotoh, Kazuyoshi| Matsushita, Osamu| Watanabe, Akari| Yokota, Kenji|
Keywords Helicobacter pylori nitrate-reducing bacteria IL-8 TNF-alpha cell cycle
Published Date 2022-12-16
Publication Title Microorganisms
Volume volume10
Issue issue12
Publisher MDPI
Start Page 2495
ISSN 2076-2607
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36557748
DOI 10.3390/microorganisms10122495
Web of Science KeyUT 000903731600001
Related Url isVersionOf https://doi.org/10.3390/microorganisms10122495
FullText URL fulltext20230110-1.pdf Table1_20230110-1.pdf Table2_20230110-1.pdf Table3_20230110-1.pdf Table4_20230110-1.pdf Figure 1A.jpg Figure 1B.jpg Figure 1C.jpg Figure 1D.jpg Figure 1E.jpg Figure 1F.jpg
Author Matsumoto, Kazuyuki| Kato, Hironari|
Keywords ablation techniques endoscopic ultrasonography ethanol pancreatic neoplasms radiofrequency ablation
Note This is the peer reviewed version of the following article: [Matsumoto, K. and Kato, H. (2023), Endoscopic ablation therapy for the pancreatic neoplasms. Digestive Endoscopy. https://doi.org/10.1111/den.14468], which has been published in final form at [https://doi.org/10.1111/den.14468]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This full-text file will be available in Dec. 2023.|
Published Date 2022-12-13
Publication Title Digestive Endoscopy
Volume volume35
Issue issue4
Publisher Wiley
Start Page 430
End Page 442
ISSN 0915-5635
NCID AA10907137
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Japan Gastroenterological Endoscopy Society.
File Version author
PubMed ID 36366955
DOI 10.1111/den.14468
Web of Science KeyUT 000897965200001
Related Url isVersionOf https://doi.org/10.1111/den.14468
FullText URL fulltext.pdf
Author Fujii, Yuki| Matsumoto, Kazuyuki| Miyamoto, Kazuya| Matsumi, Akihiro| Morimoto, Kosaku| Terasawa, Hiroyuki| Yamazaki, Tatsuhiro| Horiguchi, Shigeru| Tsutsumi, Koichiro| Kato, Hironari|
Keywords biliary stent endoscope migration perforation
Published Date 2022-12-02
Publication Title MEDICINE
Volume volume101
Issue issue48
Publisher LIPPINCOTT WILLIAMS & WILKINS
Start Page e31868
ISSN 0025-7974
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 the Author(s).
File Version publisher
PubMed ID 36482637
DOI 10.1097/MD.0000000000031868
Web of Science KeyUT 000895502600121
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000031868
FullText URL fulltext.pdf
Author Takagi, Kosei| Umeda, Yuzo| Yoshida, Ryuichi| Fuji, Tomokazu| Yasui, Kazuya| Kimura, Jiro| Hata, Nanako| Mishima, Kento| Yagi, Takahito| Fujiwara, Toshiyoshi|
Keywords robotic surgery pancreatoduodenectomy surgical approach superior mesenteric artery pancreatic cancer
Published Date 2022-11-30
Publication Title Journal Of Clinical Medicine
Volume volume11
Issue issue23
Publisher MDPI
Start Page 7112
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36498684
DOI 10.3390/jcm11237112
Web of Science KeyUT 000896167800001
Related Url isVersionOf https://doi.org/10.3390/jcm11237112
FullText URL fulltext.pdf
Author Umeda, Yuzo| Takagi, Kosei| Matsuda, Tatsuo| Fuji, Tomokazu| Kojima, Toru| Satoh, Daisuke| Hioki, Masayoshi| Endo, Yoshikatsu| Inagaki, Masaru| Oishi, Masahiro| Yagi, Takahito| Fujiwara, Toshiyoshi|
Keywords intrahepatic cholangiocarcinoma lymphadenectomy multicenter study retrospective study
Published Date 2022-11-27
Publication Title Annals Of Gastroenterological Surgery
Publisher Wiley
ISSN 2475-0328
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
DOI 10.1002/ags3.12642
Web of Science KeyUT 000891179400001
Related Url isVersionOf https://doi.org/10.1002/ags3.12642
FullText URL fulltext.pdf
Author Takeuchi, Yasuto| Kato, Hironari| Horiguchi, Shigeru| Oyama, Atsushi| Adachi, Takuya| Wada, Nozomu| Onishi, Hideki| Shiraha, Hidenori| Takaki, Akinobu|
Keywords NETs TAE clinical trial
Published Date 2022
Publication Title Clinical Medicine Insights-Oncology
Volume volume16
Publisher Sage Publications Ltd.
Start Page 1
End Page 5
ISSN 1179-5549
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 36387610
DOI 10.1177/11795549221127750
Web of Science KeyUT 000888437000001
Related Url isVersionOf https://doi.org/10.1177/11795549221127750
FullText URL fulltext.pdf
Author Kakiuchi, Yoshihiko| Kikuchi, Satoru| Kuroda, Shinji| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Keywords Remnant gastric cancer Prognostic factor Tumor-infiltrating lymphocytes CD8(+) T cell Tumor immunity
Published Date 2022-11-30
Publication Title World Journal Of Surgical Oncology
Volume volume20
Issue issue1
Publisher BMC
Start Page 374
ISSN 1477-7819
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 36451224
DOI 10.1186/s12957-022-02853-2
Web of Science KeyUT 000892980100002
Related Url isVersionOf https://doi.org/10.1186/s12957-022-02853-2
FullText URL fulltext20221215-1.pdf figures20221215-1.pdf Supple_Figures20221215-1.pdf Supple_Table20221215-1.pdf
Author Kajiwara, Yoshinori| Tazawa, Hiroshi| Yamada, Motohiko| Kanaya, Nobuhiko| Fushimi, Takuro| Kikuchi, Satoru| Kuroda, Shinji| Ohara, Toshiaki| Noma, Kazuhiro| Yoshida, Ryuichi| Umeda, Yuzo| Urata, Yasuo| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Keywords Pancreatic cancer Chemoresistance MDSC GM-CSF Oncolytic virus
Note This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00262-022-03334-x| This full-text of the article will be available in Nov. 2023.|
Published Date 2022-11-27
Publication Title Cancer Immunology, Immunotherapy
Volume volume72
Issue issue5
Publisher Springer Science and Business Media LLC
Start Page 1285
End Page 1300
ISSN 0340-7004
NCID AA00598499
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022
File Version author
PubMed ID 36436021
DOI 10.1007/s00262-022-03334-x
Web of Science KeyUT 000889040300003
Related Url isVersionOf https://doi.org/10.1007/s00262-022-03334-x
FullText URL fulltext.pdf
Author Sato, Hiroaki| Noma, Kazuhiro| Ohara, Toshiaki| Kawasaki, Kento| Akai, Masaaki| Kobayashi, Teruki| Nishiwaki, Noriyuki| Narusaka, Toru| Komoto, Satoshi| Kashima, Hajime| Katsura, Yuki| Kato, Takuya| Kikuchi, Satoru| Tazawa, Hiroshi| Kagawa, Shunsuke| Shirakawa, Yasuhiro| Kobayashi, Hisataka| Fujiwara, Toshiyoshi|
Published Date 2022-11-23
Publication Title Scientific Reports
Volume volume12
Issue issue1
Publisher Nature Portfolio
Start Page 20152
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 36418422
DOI 10.1038/s41598-022-24313-3
Web of Science KeyUT 000887936300054
Related Url isVersionOf https://doi.org/10.1038/s41598-022-24313-3
FullText URL fulltext20221130-3.pdf
Author Sato, Ryosuke| Matsumoto, Kazuyuki| Kanzaki, Hiromitsu| Matsumi, Akihiro| Miyamoto, Kazuya| Morimoto, Kosaku| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Tsutsumi, Koichiro| Horiguchi, Shigeru| Kato, Hironari|
Keywords Endoscopic ultrasound-guided fine needle aspiration Linitis plastica Autoimmune pancreatitis Paraneoplastic syndromes Case report
Note Sato R, Matsumoto K, Kanzaki H, Matsumi A, Miyamoto K, Morimoto K, Terasawa H, Fujii Y, Yamazaki T, Uchida D, Tsutsumi K, Horiguchi S, Kato H. Gastric linitis plastica with autoimmune pancreatitis diagnosed by an endoscopic ultrasonography-guided fine-needle biopsy: A case report. World J Clin Cases 2022; 10(31): 11607-11616 [PMID: 36387831 DOI: 10.12998/wjcc.v10.i31.11607]|
Published Date 2022-11-6
Publication Title World Journal of Clinical Cases
Volume volume10
Issue issue31
Publisher Baishideng Publishing Group Inc.
Start Page 11607
End Page 11616
ISSN 2307-8960
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders ©The Author(s) 2022
File Version publisher
PubMed ID 36387831
DOI 10.12998/wjcc.v10.i31.11607
Web of Science KeyUT 000885256200043
FullText URL fulltext.pdf
Author Tsuge, Mitsuru| Kodera, Aya| Sumitomo, Hiromi| Araki, Tooru| Yoshida, Ryuichi| Yasui, Kazuya| Sato, Hiroki| Washio, Yosuke| Washio, Kana| Shigehara, Kenji| Yashiro, Masato| Yagi, Takahito| Tsukahara, Hirokazu|
Keywords Neonatal hemochromatosis Thalassemia Liver transplantation Gestational alloimmune liver disease Case report Hepcidin Ineffective erythropoiesis Growth differentiation factor-15
Published Date 2022-10-29
Publication Title BMC Pediatrics
Volume volume22
Issue issue1
Publisher BMC
Start Page 622
ISSN 1471-2431
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 36309641
DOI 10.1186/s12887-022-03706-3
Web of Science KeyUT 000876287400002
Related Url isVersionOf https://doi.org/10.1186/s12887-022-03706-3
JaLCDOI 10.18926/AMO/64120
FullText URL 76_6_695.pdf
Author Onishi, Hideki| Nouso, Kazuhiro| Takaki, Akinobu| Oyama, Atsushi| Adachi, Takuya| Wada, Nozomu| Takeuchi, Yasuto| Shiraha, Hidenori| Okada, Hiroyuki|
Abstract This study sought to identify factors that are predictive of a therapeutic response to hepatic arterial infusion chemotherapy (HAIC) by focusing on the number of prior transcatheter arterial chemoembolization (TACE) sessions. To determine the parameters predicting a good response to HAIC, we retrospectively analyzed 170 patients with hepatocellular carcinoma (HCC) who received HAIC regimens comprising low-dose cisplatin combined with 5-fluorouracil (LFP) or cisplatin (CDDP) for the first time. In both the LFP and CDDP regimens, the response rates were significantly lower in patients with three or more prior TACE sessions than in those with two or fewer prior TACE sessions (LFP 57% versus 28%; p=0.01, CDDP 27% versus 6%; p=0.01). Multivariable logistic regression analysis revealed that the number of prior TACE sessions (≥ 3) was significantly associated with non-responder status (odds ratio 4.17, 95% Confidence Interval (CI) 1.76-9.86) in addition to the HAIC regimen. Multivariable analysis using the Cox proportional hazards model revealed that a larger number of prior TACE sessions (≥ 3) was a significant risk factor for survival (hazard ratio 1.60, 95% CI 1.12-2.29) in addition to Child-Pugh class, serum alpha-fetoprotein concentration, and maximum diameter of HCC. HCC patients who receive fewer prior TACE sessions (≤ 2) were found to be better responders to HAIC.
Keywords hepatic arterial infusion chemotherapy hepatocellular carcinoma refractory transcatheter arterial chemoembolization
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-12
Volume volume76
Issue issue6
Publisher Okayama University Medical School
Start Page 695
End Page 703
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36549772
Web of Science KeyUT 000905195100010
JaLCDOI 10.18926/AMO/64043
FullText URL 76_5_605.pdf
Author Teraishi, Fuminori| Jikuhara, Atsushi| Ogawa, Ryunosuke| Fujiwara, Toshiyoshi|
Abstract An 84-year-old female underwent open right hemicolectomy with D3 lymph node dissection for cecal cancer, pathologically identified as pT4aN2M0 Stage IIIc and BRAF mutation-positive. Due to early recurrence of abdominal wall and right lateral lymph nodes, the patient was treated with FOLFOXIRI+Bevacizumab. Imaging after 5 courses of chemotherapy found tumor shrinkage and no new metastases. The patient did not tolerate chemotherapy well, and tumor resection was performed. Microsatellite instability (MSI) testing using multiplex polymerase chain reaction (PCR) fragment analysis revealed MSI-high status. The patient is currently recurrence-free without chemotherapy at 1 year postoperatively. BRAF-mutated colorectal cancer has a poor prognosis, and may require resection of the metastatic or recurrent tumor after comprehensive evaluation.
Keywords BRAF V600E mutation cecal cancer, MSI-high
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2022-10
Volume volume76
Issue issue5
Publisher Okayama University Medical School
Start Page 605
End Page 608
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36352809
Web of Science KeyUT 000884907100015
FullText URL fulltext.pdf
Author Araki, Hiroyuki| Tazawa, Hiroshi| Kanaya, Nobuhiko| Kajiwara, Yoshinori| Yamada, Motohiko| Hashimoto, Masashi| Kikuchi, Satoru| Kuroda, Shinji| Yoshida, Ryuichi| Umeda, Yuzo| Urata, Yasuo| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Published Date 2022-12-15
Publication Title Molecular Therapy - Oncolytics
Volume volume27
Publisher Cell Press
Start Page 3
End Page 13
ISSN 2372-7705
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Author(s).
File Version publisher
PubMed ID 36212775
DOI 10.1016/j.omto.2022.09.003
Web of Science KeyUT 000870232500001
Related Url isVersionOf https://doi.org/10.1016/j.omto.2022.09.003
FullText URL fulltext.pdf
Author Takagi, Kosei| Murotani, Kenta| Kamoshita, Satoru| Kuroda, Akiyoshi|
Keywords Parenteral nutrition Lipid injectable emulsion Medical inpatient Clinical outcome Real-world data
Published Date 2022-10-27
Publication Title BMC Medicine
Volume volume20
Issue issue1
Publisher BMC
Start Page 371
ISSN 1741-7015
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 36289527
DOI 10.1186/s12916-022-02568-x
Web of Science KeyUT 000873785800002
Related Url isVersionOf https://doi.org/10.1186/s12916-022-02568-x
FullText URL fulltext.pdf
Author Matsumoto, Kazuyuki| Mitsuhashi, Toshiharu| Kawamoto, Hirofumi| Ishida, Etsuji| Fujii, Masakuni| Akimoto, Yutaka| Seki, Hiroyuki| Ishihara, Yuki| Ogawa, Taiji| Yamazaki, Tatsuhiro| Fujii, Yuki| Kato, Hironari|
Keywords bilateral drainage bile duct obstruction endoscopic biliary drainage neoplasms self-expandable metallic stents
Published Date 2022-10-07
Publication Title Medicine
Volume volume101
Issue issue40
Publisher Lippincott Williams & Wilkins
Start Page e30857
ISSN 0025-7974
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 the Author(s).
File Version publisher
PubMed ID 36221399
DOI 10.1097/MD.0000000000030857
Web of Science KeyUT 000865518700110
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000030857