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Author Hirosuna, Kensuke| Kashima, Hajime| Shoji, Ryohei| Matsumi, Yuki| Kakiuchi, Yoshihiko| Kikuchi, Satoru| Kuroda, Shinji| Teraishi, Fuminori| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Keywords obese patient gastric diverticulum sleeve gastrectomy metabolic surgery bariatric surgery endoscopic measurement
Published Date 2025
Publication Title Surgical Case Reports
Volume volume11
Issue issue1
Publisher Japan Surgical Society
Start Page cr.25-0141
ISSN 2198-7793
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40511451
DOI 10.70352/scrj.cr.25-0141
Web of Science KeyUT 001533538200002
Related Url isVersionOf https://doi.org/10.70352/scrj.cr.25-0141
FullText URL fulltext.pdf
Author Mimata, Yudai| Kanaya, Nobuhiko| Kondo, Yoshitaka| Minagi, Hitoshi| Kakiuchi, Yoshihiko| Kuroda, Shinji| Shigeyasu, Kunitoshi| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Keywords segmental arterial mediolysis laparoscopic partial omentectomy hemoperitoneum
Published Date 2025
Publication Title Surgical Case Reports
Volume volume11
Issue issue1
Publisher Japan Surgical Society
Start Page cr.25-0262
ISSN 2198-7793
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40667458
DOI 10.70352/scrj.cr.25-0262
CRID 1390586344769723136
Web of Science KeyUT 001531844700001
Related Url isVersionOf https://doi.org/10.70352/scrj.cr.25-0262
FullText URL fulltext.pdf
Author Tanaka, Shin| Umeda, Masashi| Ujike, Hiroyuki| Ryuko, Tsuyoshi| Tomioka, Yasuaki| Miyoshi, Kentaroh| Okazaki, Mikio| Sugimoto, Seiichiro| Toyooka, Shinichi|
Keywords Lung preservation Donation after circulatory death Abdominal normothermic regional perfusion
Note The version of record of this article, first published in General Thoracic and Cardiovascular Surgery, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11748-025-02137-y|
Published Date 2025-03-16
Publication Title General Thoracic and Cardiovascular Surgery
Publisher Springer Science and Business Media LLC
ISSN 1863-6705
NCID AA12201344
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40089938
DOI 10.1007/s11748-025-02137-y
Web of Science KeyUT 001446042300001
Related Url isVersionOf https://doi.org/10.1007/s11748-025-02137-y
FullText URL fulltext.pdf correction.pdf
Author Miyahara, Hiroyuki| Shigeyasu, Yoshie| Fujii, Chikako| Tanaka, Chie| Mana, Hanzawa| Sugihara, Akiko| Okada, Ayumi| Tsukahara, Hirokazu|
Keywords Anorexia nervosa Dehydration Glomerular filtration rate estimated using creatinine Glomerular filtration rate estimated using cystatin-C Hypokalemia Low free triiodothyronine syndrome
Note The version of record of this article, first published in BioPsychoSocial Medicine, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13030-024-00316-6|
Published Date 2024-09-29
Publication Title BioPsychoSocial Medicine
Volume volume18
Issue issue1
Publisher BMC
Start Page 19
ISSN 1751-0759
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 39343908
DOI 10.1186/s13030-024-00316-6
Web of Science KeyUT 001321447000001
Related Url isVersionOf https://doi.org/10.1186/s13030-024-00316-6
JaLCDOI 10.18926/AMO/67554
FullText URL 78_4_349.pdf
Author Tominaga, Yuichiro| Sugaya, Akiko| Kariya, Shin| Shimizu, Aiko| Kataoka, Yuko| Ando, Mizuo|
Abstract Middle-ear salivary gland choristoma (SGCh) is a rare, benign tumor that causes conductive hearing loss owing to middle-ear morphological abnormalities. Early diagnosis is challenging, and surgical resection is indispensable for a definitive diagnosis. We report the case of a 3-year-old boy diagnosed with middle-ear SGCh during the follow-up period for left-sided hearing loss discovered at newborn hearing screening (NHS). Long-term follow-up after the NHS result, subsequent computed tomography/magnetic resonance imaging, and surgical resection led to its relatively early diagnosis and treatment.
Keywords middle-ear salivary gland choristoma middle-ear morphological abnormalities newborn hearing screening unilateral hearing loss surgical resection
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-08
Volume volume78
Issue issue4
Publisher Okayama University Medical School
Start Page 349
End Page 355
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39198990
Web of Science KeyUT 001310557400004
FullText URL fulltext20240531-01.pdf
Author Tanaka, Takaaki| Taoka, Masataka| Makimoto, Go| Ninomiya, Kiichiro| Higo, Hisao| Fujii, Masanori| Ichihara, Eiki| Ohashi, Kadoaki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu|
Keywords immune checkpoint inhibitor nivolumab ipilimumab cytokine release syndrome immune effector cell-associated neurotoxicity syndrome
Published Date 2024-05-01
Publication Title Internal Medicine
Volume volume63
Issue issue9
Publisher Japanese Society of Internal Medicine
Start Page 1261
End Page 1267
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 37722894
DOI 10.2169/internalmedicine.2429-23
Web of Science KeyUT 001223220900001
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.2429-23
JaLCDOI 10.18926/AMO/66148
FullText URL 77_6_567.pdf
Author Matsumoto, Naomi| Higuchi, Chigusa| Miyaji, Chikara| Mitsuhashi, Toshiharu| Hagiya, Hideharu| Takao, Soshi| Yorifuji, Takashi|
Abstract This paper presents the results of a series of surveys conducted from July 2021 to March 2023 to investigate the post-vaccination adverse reactions to the mRNA-1273 (Moderna) vaccine among faculty, staff, and students at Okayama University. These studies complement the official surveys conducted by the Ministry of Health, Labour and Welfare (MHLW) and provide a more representative picture of adverse reactions in the general population including large numbers of healthy young people. Pain, swelling, redness at the injection site, fever, headache, and malaise were the main adverse reactions reported. The proportion of adverse reactions was generally higher after the second vaccination and decreased with each additional vaccination. No statistically significant differences in the adverse reactions were found for males and females and those with/without a history of allergy, but a lower proportion of fever was observed in older participants and those with underlying medical conditions. We also evaluated the association between adverse reactions and antibody titers after the third vaccination and found no significant differences in antibody levels one month after vaccination. This series of studies highlights the importance of conducting surveys in diverse populations to provide a more representative picture of post-vaccination adverse reactions during a pandemic.
Keywords coronavirus disease 2019 adverse reactions mRNA vaccine antibody titers young adults
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 567
End Page 575
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145930
Web of Science KeyUT 001164631200001
JaLCDOI 10.18926/AMO/65748
FullText URL 77_4_377.pdf
Author Morimoto, Kosaku| Takeuchi, Yasuto| Takaki, Akinobu| Wada, Nozomu| Oyama, Atsushi| Adachi, Takuya| Onishi, Hideki| Shiraha, Hidenori| Okada, Hiroyuki|
Abstract Liver fibrosis is an important phenomenon in non-alcoholic fatty liver disease (NAFLD) progression. Standard markers reflecting liver fibrosis, including the FIB-4 index, increase with age. This study aimed to identify fibrosis progression-related markers that are diagnostically beneficial even in aged individuals. Serum levels of pro- and anti-inflammatory cytokines were measured by multiple enzyme-linked immunosorbent assay. Two standard NAFLD or fibrosis progression-related markers — the FIB-4 index and APRI score — were analyzed along with cytokine levels to define the best approach to discriminate advanced fibrosis. Ninety-eight NAFLD patients were enrolled: 59 and 39 patients with fibrosis stages 1-2 and 3-4 respectively. In addition to the FIB-4 index and APRI score, the following factors showed significant differences between stages 1-2 and stages 3-4 in a multivariate analysis: platelet counts, IP-10, and RANTES. The fibrosis stage, FIB-4, APRI, PDGF-BB, and RANTES were related to the prognosis. In aged patients, IP-10, GM-CSF, and RANTES differed between stages 1-2 and stages 3-4. FIB-4 and APRI were beneficial for their correlation with fibrosis. However, to stratify either young or elderly advanced fibrosis patients, and to identify patients likely to have a bad outcome, RANTES was the best marker.
Keywords NAFLD NASH liver fibrosis chemokine FIB-4
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 377
End Page 385
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635138
Web of Science KeyUT 001163659800009
FullText URL fulltext.pdf
Author Matsuoka-Uchiyama, Natsumi| Tsuji, Kenji| Takahashi, Kensaku| Fukushima, Kazuhiko| Takeuchi, Hidemi| Kitamura, Shinji| Inagaki, Kenichi| Uchida, Haruhito A. A.| Wada, Jun|
Keywords hypothyroidism kidney function urinary creatinine excretion
Published Date 2023-02-10
Publication Title Diagnostics
Volume volume13
Issue issue4
Publisher MDPI
Start Page 669
ISSN 2075-4418
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 36832157
DOI 10.3390/diagnostics13040669
Web of Science KeyUT 000939117200001
Related Url isVersionOf https://doi.org/10.3390/diagnostics13040669
JaLCDOI 10.18926/AMO/64364
FullText URL 77_1_71.pdf
Author Yamakawa, Yasuaki| Kamatsuki, Yusuke| Noda, Tomoyuki| Kure, Miho| Miyazawa, Shinichi| Ozaki, Toshifumi|
Abstract We report a case of ipsilateral periprosthetic fractures above and below the knee that occurred at different times due to navigation tracker pin and bone fragility. A 66-year-old Japanese woman with rheumatoid arthritis (RA) underwent a total knee arthroplasty. Four months post-surgery, a periprosthetic fracture above the knee at the navigation pin hole was detected. She underwent osteosynthesis and could walk independently, but she developed an ipsilateral tibial component fracture. Conservative treatment with a splint was followed by bone union. Patients with RA treated with oral steroids tend to develop ipsilateral periprosthetic fractures around the knee due to bone fragility.
Keywords periprosthetic fracture total knee arthroplasty navigation system bone fragility
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 71
End Page 74
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849147
Web of Science KeyUT 000952992100005
FullText URL fulltext20230110-1.pdf Table1_20230110-1.pdf Table2_20230110-1.pdf Table3_20230110-1.pdf Table4_20230110-1.pdf Figure 1A.jpg Figure 1B.jpg Figure 1C.jpg Figure 1D.jpg Figure 1E.jpg Figure 1F.jpg
Author Matsumoto, Kazuyuki| Kato, Hironari|
Keywords ablation techniques endoscopic ultrasonography ethanol pancreatic neoplasms radiofrequency ablation
Note This is the peer reviewed version of the following article: [Matsumoto, K. and Kato, H. (2023), Endoscopic ablation therapy for the pancreatic neoplasms. Digestive Endoscopy. https://doi.org/10.1111/den.14468], which has been published in final form at [https://doi.org/10.1111/den.14468]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This full-text file will be available in Dec. 2023.|
Published Date 2022-12-13
Publication Title Digestive Endoscopy
Volume volume35
Issue issue4
Publisher Wiley
Start Page 430
End Page 442
ISSN 0915-5635
NCID AA10907137
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Japan Gastroenterological Endoscopy Society.
File Version author
PubMed ID 36366955
DOI 10.1111/den.14468
Web of Science KeyUT 000897965200001
Related Url isVersionOf https://doi.org/10.1111/den.14468
FullText URL fulltext.pdf
Author Matsuoka-Uchiyama, Natsumi| Tsuji, Kenji| Sang, Yizhen| Takahashi, Kensaku| Fukushima, Kazuhiko| Takeuchi, Hidemi| Inagaki, Kenichi| Uchida, Haruhito A.| Kitamura, Shinji| Sugiyama, Hitoshi| Wada, Jun|
Published Date 2022-09-02
Publication Title Scientific Reports
Volume volume12
Issue issue1
Publisher Nature Portfolio
Start Page 14999
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 36056164
DOI 10.1038/s41598-022-19226-0
Web of Science KeyUT 000849436000046
Related Url isVersionOf https://doi.org/10.1038/s41598-022-19226-0
FullText URL fulltext.pdf
Author Hashimoto, Masashi| Shirakawa, Yasuhiro| Tanabe, Shunsuke| Tanaka, Takehiro| Maeda, Naoaki| Sakurama, Kazufumi| Noma, Kazuhiro| Fujiwara, Toshiyoshi|
Keywords Esophagectomy Verrucous carcinoma Esophageal squamous cell carcinoma
Published Date 2022-07-04
Publication Title Surgical Case Reports
Volume volume8
Issue issue1
Publisher Springer
Start Page 128
ISSN 2198-7793
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 35781764
DOI 10.1186/s40792-022-01486-7
Web of Science KeyUT 000820644000001
Related Url isVersionOf https://doi.org/10.1186/s40792-022-01486-7
JaLCDOI 10.18926/AMO/62817
FullText URL 75_6_751.pdf
Author Endo, Hirosuke| Yamada, Kazuki| Testunaga, Tomonori| Furumatsu, Takayuki| Mitani, Shigeru| Ozaki, Toshifumi|
Abstract The improved cemented cup technique has attained excellent long-term results in primary total hip arthroplasty. When cup revision surgery was performed, the cemented cup, which was loosened at the bone-cement interface, was easily removed. However, with a well-fixed bone-cement interface, it remains difficult to remove the cemented cup for a revision in the event of a recurring dislocation. In addition, protrusions in the cement can cause unpredictable bone defects. A new removal device was created and used successfully to remove a well-fixed cemented cup safely and efficiently. This report introduces the device and the technique used in cemented cup removal.
Keywords total hip arthroplasty revision surgery well-fixed cemented cup
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-12
Volume volume75
Issue issue6
Publisher Okayama University Medical School
Start Page 751
End Page 754
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34955545
Web of Science KeyUT 000735319800003
NAID 120007180275
JaLCDOI 10.18926/AMO/62410
FullText URL 75_4_543.pdf
Author Yoshida, Ryuichi| Yagi, Takahito| Yasui, Kazuya| Umeda, Yuzo| Yoshida, Kazuhiro| Fuji, Tomokazu| Takagi, Kosei| Kumano, Kenjiro| Yoshimoto, Masashi| Fujiwara, Toshiyoshi|
Abstract The outcomes of pancreatectomy with resection and reconstruction of the involved arteries for locally advanced pancreatic cancer following chemotherapy have improved in recent years. In pancreatic head cancers in which there is contact with the common and proper hepatic arteries, margin-negative resection requires pancreati-coduodenectomy, with the resection of these arteries and the restoration of hepatic arterial flow. Here, we describe a middle colic artery transposition technique in hepatic arterial reconstruction during pancreatoduo-denectomy for an initially unresectable locally advanced pancreatic cancer. This technique was effective and may provide a new option for hepatic artery reconstruction in such cases.
Keywords hepatic artery locally advanced pancreatic cancer middle colic artery pancreatoduodenectomy reconstruction technique
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 543
End Page 548
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511625
Web of Science KeyUT 000696755800004
NAID 120007146036
FullText URL fulltext20210831-3.pdf
Author Shirakawa, Yasuhiro| Tazawa, Hiroshi| Tanabe, Shunsuke| Kanaya, Nobuhiko| Noma, Kazuhiro| Koujima, Takeshi| Kashima, Hajime| Kato, Takuya| Kuroda, Shinji| Kikuchi, Satoru| Kagawa, Shunsuke| Katsui, Kuniaki| Kanazawa, Susumu| Urata, Yasuo| Fujiwara, Toshiyoshi|
Keywords Telomerase adenovirus radiotherapy esophageal cancer immunotherapy
Note © 2021 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.ejca.2021.04.043] .|
Published Date 2021-8
Publication Title European Journal of Cancer
Volume volume153
Publisher Elsevier BV
Start Page 98
End Page 108
ISSN 0959-8049
NCID AA1075407X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Elsevier Ltd.
File Version author
PubMed ID 34153720
DOI 10.1016/j.ejca.2021.04.043
Web of Science KeyUT 000686051300013
Related Url isVersionOf https://doi.org/10.1016/j.ejca.2021.04.043
JaLCDOI 10.18926/AMO/61906
FullText URL 75_2_231.pdf
Author Endo, Motochika| Yano, Shuya| Asano, Hiroaki| Takeda, Sho| Hamada, Yuki| Kondo, Yoshitaka| Kuroda, Shinji| Shigeyasu, Kunitoshi| Kikuchi, Satoru| Tanaka, Takehiro| Teraishi, Fuminori| Nishizaki, Masahiko| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Abstract Targeted therapies for malignant melanoma have improved patients’ prognoses. A primary gastrointestinal malignant melanoma is very rare, with no standard treatment strategy. We treated a 78-year-old Japanese female with advanced primary gastrointestinal melanoma of the descending colon and gallbladder. We administered a multidisciplinary treatment: surgical resection of the descending colon and gallbladder tumors, resection of the metastatic lymph nodes behind the pancreas head, and immune checkpoint antibody-blockade therapy (nivolumab) for ~4 years. PET/CT demonstrated no recurrent lesion for > 3 years. Multidisciplinary therapies (e.g., surgery, chemotherapy, radiotherapy, target therapy, and immune checkpoint antibody-blockade therapy) can successfully treat primary gastrointestinal malignant melanoma.
Keywords primary gastrointestinal melanoma laparoscopic surgery immune checkpoint antibody-blockade inhibitor
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 231
End Page 238
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953431
NAID 120007029881
JaLCDOI 10.18926/AMO/61439
FullText URL 75_1_87.pdf
Author Shiotani, Toshio| Sugimoto, Seiichiro| Araki, Kota| Tomioka, Yasuaki| Miyoshi, Kentaroh| Otani, Shinji| Yamane, Masaomi| Toyooka, Shinichi|
Abstract Although chronic kidney disease (CKD) commonly develops after lung transplantation (LT), living-donor kid-ney transplantation (LDKT) for CKD after LT is known to provide favorable outcomes. We describe the long-term follow-up findings of a patient who underwent LDKT after bilateral cadaveric LT. A 37-year-old male underwent LDKT for CKD 18 years after receiving bilateral cadaveric LT. He developed chronic lung allograft dysfunction (CLAD) 20 years after the LT; however, at 26 years after the initial LT, he is still alive with no pro-gression of CLAD or CKD. KT could be a viable option for CKD even after LT in Japan.
Keywords lung transplantation kidney transplantation chronic kidney disease non-tuberculous mycobacterial infection chronic lung allograft dysfunction
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-02
Volume volume75
Issue issue1
Publisher Okayama University Medical School
Start Page 87
End Page 89
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33649618
JaLCDOI 10.18926/AMO/60799
FullText URL 74_5_401.pdf
Author Tsukioki, Takahiro| Shien, Tadahiko| Ohtani, Yusuke| Fujihara, Miwa| Suzuki, Yoko| Kajihara, Yukiko| Hatono, Minami| Kawada, Kengo| Kochi, Mariko| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Doihara, Hiroyoshi|
Abstract Differentiated thyroid carcinoma (DTC) in juvenile patients is often an extensive and aggressive disease with a high frequency of recurrence. However, the prognosis is excellent, with a low mortality rate even when advanced disease is present, although prognostic factors and treatment strategy remain uncertain. Between April 2004 and March 2017, 33 juvenile patients (< 30 years old) were diagnosed with DTC and treated at our institution. We retrospectively investigated prognosis and factors including sex, reason for discovery, treatment, pathological factors and treatment progress to clarify the risk factors. All patients underwent curative surgical treatment. Pathologically, lymph node metastasis was identified in 25 patients (75%). Thirteen patients (39%) had bilateral cervical metastasis. In addition, 9 (27%) had more than 10 metastatic lymph nodes. The 2 patients with more than 20 metastatic lymph nodes were treated with radioactive iodine (RAI). Five patients (15%) had local recurrences and received surgery. There have been no further recurrences or deaths. However, no factors were determined to significantly predict the recurrence of juvenile DTC. Local recurrent disease was treated with surgery and/or RAI until remission, and survival was excellent in juvenile DTC.
Keywords differentiated thyroid carcinoma juvenile children
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-10
Volume volume74
Issue issue5
Publisher Okayama University Medical School
Start Page 401
End Page 406
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33106695
Web of Science KeyUT 000581970100004
NAID 120006892925
JaLCDOI 10.18926/AMO/60797
FullText URL 74_5_381.pdf
Author Yamamoto, Koichiro| Hanayama, Yoshihisa| Hasegawa, Kou| Tokumasu, Kazuki| Miyoshi, Tomoko| Hagiya, Hideharu| Ogawa, Hiroko| Obika, Mikako| Itoshima, Koichi| Otsuka, Fumio|
Abstract To clarify the relevance of prolactin (PRL) to clinical parameters in patients who visited our general medicine department, medical records of 353 patients in whom serum PRL levels were measured during the period from 2016 to 2018 were retrospectively reviewed. Data for 140 patients (M/F: 42/98) were analyzed after excluding patients lacking detailed records and patients taking dopaminergic agents. Median serum PRL levels were significantly lower in males than females: 6.5 ng/ml (IQR: 4.2-10.3) versus 8.1 ng/ml (5.9-12.9), respectively. Pain and general fatigue were the major symptoms at the first visit, and past histories of hypertension and dyslipidemia were frequent. Male patients with relatively high PRL levels (≥ 10 ng/ml) had significantly lower levels of serum albumin and significantly higher levels of serum LDH than those with low PRL (< 10 ng/ml). There were significant correlations of male PRL level with the erythrocyte sedimentation rate (R=0.62), serum LDH level (R=0.39) and serum albumin level (R=−0.52), while the level of serum CRP (R=0.33) showed an insignificant but weak positive correlation with PRL level. Collectively, these results show that PRL levels had gender-specific relevance to various clinical factors, with PRL levels in males being significantly related to inflammatory status.
Keywords hormones hyperprolactinemia inflammation pituitary prolactin
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-10
Volume volume74
Issue issue5
Publisher Okayama University Medical School
Start Page 381
End Page 389
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33106693
Web of Science KeyUT 000581970100002
NAID 120006892923